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# ![@gregmushen Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::14200022.png) @gregmushen Greg Mushen

Greg Mushen posts on X about colon, carnivore, drops, protocol the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXX engagements in the last XX hours.

### Engagements: XXXXX [#](/creator/twitter::14200022/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::14200022/c:line/m:interactions.svg)

- X Week XXXXXXX +44%
- X Month XXXXXXX +79%
- X Months XXXXXXXXX -XX%
- X Year XXXXXXXXXX +2,758%

### Mentions: XX [#](/creator/twitter::14200022/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::14200022/c:line/m:posts_active.svg)

- X Week XXX -XXXX%
- X Month XXX +123%
- X Months XXX +60%
- X Year XXX +303%

### Followers: XXXXXX [#](/creator/twitter::14200022/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::14200022/c:line/m:followers.svg)

- X Week XXXXXX +0.85%
- X Month XXXXXX +2.30%
- X Months XXXXXX +23%
- X Year XXXXXX +92%

### CreatorRank: XXXXXXX [#](/creator/twitter::14200022/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::14200022/c:line/m:influencer_rank.svg)

### Social Influence [#](/creator/twitter::14200022/influence)
---

**Social category influence**
[celebrities](/list/celebrities)  XXXX% [musicians](/list/musicians)  XXXX%

**Social topic influence**
[colon](/topic/colon) 1.72%, [carnivore](/topic/carnivore) 1.72%, [drops](/topic/drops) 0.86%, [protocol](/topic/protocol) 0.86%, [dolly parton](/topic/dolly-parton) 0.86%, [beta](/topic/beta) 0.86%, [gum](/topic/gum) 0.86%, [bananas](/topic/bananas) 0.86%, [dna](/topic/dna) 0.86%, [surge](/topic/surge) XXXX%

**Top accounts mentioned or mentioned by**
[@davidgmillsatty](/creator/undefined) [@arteesun](/creator/undefined) [@lebosquet](/creator/undefined) [@ultimape](/creator/undefined) [@veganchristian3](/creator/undefined) [@bowtiedgatordds](/creator/undefined) [@tuckergoodrich](/creator/undefined) [@nutrivorec](/creator/undefined) [@xdb500](/creator/undefined) [@drbreteho](/creator/undefined) [@jcdfitness](/creator/undefined) [@manjelievskaiaj](/creator/undefined) [@nutridetect](/creator/undefined) [@coffeeblackmd](/creator/undefined) [@bowtiedhrt](/creator/undefined) [@william_chris2p](/creator/undefined) [@tuluminati888](/creator/undefined) [@gregnotsure](/creator/undefined) [@drryanpdaly](/creator/undefined) [@bwhite4363](/creator/undefined)
### Top Social Posts [#](/creator/twitter::14200022/posts)
---
Top posts by engagements in the last XX hours

"What happens to gut health on Keto/Carnivore Can you still have a health gut"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948925808879477114) 2025-07-26 01:58:16 UTC 24.2K followers, 14.2K engagements


"Branched SCFA (BCFA) BCFA is a marker of protein fermentation. While it is similar chemically to SCFA but a weak agonist of FFAR2 The problem is BCFA arent a harmless byproduct. They are associated with ammonia p-cresol and biogenic amines. They are potentially cytotoxic and pro inflammatory to colonocytes"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948925855239209207) 2025-07-26 01:58:27 UTC 24.2K followers, 1193 engagements


"Summary - Butyrate drops XX percent - Colonocytes starve and trigger autophagy - BHB is not butyrate - Colon pH rises favoring proteolytic bacteria - Branched chain SCFA ammonia and ImP increase - Mucin fermentation cannot keep up - Zonulin rises the barrier breaks"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948925858095530337) 2025-07-26 01:58:28 UTC 24.2K followers, 1089 engagements


"SCFAs such a butyrate are produced primarily from fermentable fiber in the gut. On diets like carnivore there can still be SCFA production but its suboptimal and comes at a cost. - collagen can produce SCFA via proteolytic fermentation of amino acids - bile acid resistant microbiata can flourish but this can lead to imbalance - Akkermansia muciniphila can ferment mucins from the gut lining but this comes at the cost of long term barrier integrity - fermented meats and cheeses can be added. The Masai would do it this way by drinking tons of fermented milk - Supplements - either through"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1946288739229356340) 2025-07-18 19:19:30 UTC 24.2K followers, 2514 engagements


"Whos one person living or dead youd like to see on X Ill go first"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1947302216068632804) 2025-07-21 14:26:42 UTC 24.2K followers, 3933 engagements


"Since butyrate production is low there is a fallback mechanism: mucin or the gut lining. Some butyrate is needed for ATP for colonocytes. Colonocytes get around XX% of their ATP from butyrate. Taxa such as Akkermansia can ferment mucin to butyrate"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949684487581024302) 2025-07-28 04:12:59 UTC 24.2K followers, 1269 engagements


"This was the protocol PJ used. The Xs contain things that were in the protocol that he didnt use. Circles are things he did. Your doctor is right. Even with this we dont know it works. We dont know even if its lower if itll lead to better outcomes. My hypothesis is that it might be but its experimental wildly unproven and should just be interpreted as an n=2. Note that these compounds have risks and always talk to a doctor. While some of these are generally regarded as safe we dont know the impacts of stacking them. In other words talk to a doctor before you take any changes to make sure its"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1917320648122327292) 2025-04-29 20:50:39 UTC 24.2K followers, XXX engagements


"I referenced about five studies so let me know which one and I can do a more detailed breakdown. But to summarize them altogether - we know which taxa we need - we know what pH we roughly need to have those - carnivore since it lacks fiber will be at a much higher pH - higher pH will mean more proteolytic taxa - fiber is needed to bring ph down"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948012854956917234) 2025-07-23 13:30:31 UTC 24.2K followers, XX engagements


"Pathogens and inflammatory tone Higher pH oxygen leakage and nitrate favor Proteobacteria as mentioned (E. coli Salmonella). Their LPS and flagellin sustain a low grade inflammatory tone and metabolic endotoxemia"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949684531373670682) 2025-07-28 04:13:10 UTC 24.2K followers, XXX engagements


"Common misconception. Gluconeogensis is demand driven not supply driven"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948178631442022507) 2025-07-24 00:29:15 UTC 24.2K followers, 14.4K engagements


"How To Construct a Fiber Heavy Tsimane Diet To get 70g of fiber and 55g of resistant starch this is what a day of eating would look like: - 350g green plantain (boiled and cooled) - 400g red potato (cooked and cooled) - 300g jasmine rice (cooked and cooled) - 250g pinto beans (pressure cooked) - 150g of blueberries - 200g of mixed vegetables - 30g of raw mixed nuts - 390g of chicken - X tbsp of olive oil Macros Calories: 2665 Protein: 161g Carbohydrate: 347g Fat: 43g Fiber: 70g Resistant starch: 55g This would be a propionate rich SCFA profile like the Tsimane"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949273155513839714) 2025-07-27 00:58:30 UTC 24.2K followers, 16.4K engagements


"Italian food is just roman-mesoamerican fusion"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1950035035639161064) 2025-07-29 03:25:57 UTC 24.2K followers, XXX engagements


"@ManjelievskaiaJ Oh cool. Wouldnt have expected that to be at a Dolly Parton gift shop"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949564934011904432) 2025-07-27 20:17:56 UTC 24.2K followers, XX engagements


"The more I look into the microbiome and what it responds to the more it makes me think that most of the plants we evolved to eat are lost. The fibers are microbiome responds to well appear to be somewhat rare. Green bananas chicory root plantains guar gum acacia inulin from tubers beta glucan from oats. These resemble wild like plants bark roots unripe starches cooked starches that were roasted on a fire to be edible and then later cooled rhizomes (tumeric ginger galangal etc.) etc. Could explain both why some people dont do well on fiber and also why just adding more fiber without the"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949191439604490269) 2025-07-26 19:33:48 UTC 24.2K followers, 18.8K engagements


"Can you still get all your nutrients from food A common belief is that our food supply is too depleted and that hitting all your micros from food alone is nearly impossible. That can be true if youre not tracking micros and not being intentional with your food selection. But if you do track and build your meals around nutrient density its absolutely possible. Personally Ive been tracking my micronutrients and consistently hitting all targets from food alone except for vitamin D (VDR polymorphism and low light Seattle) and B vitamins (MTRR polymorphism). My go to for magnesium is a daily"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1931769809395761358) 2025-06-08 17:46:27 UTC 24.2K followers, 31.7K engagements


"@CoffeeBlackMD Haha. True. I was too lazy to make filtered coffee as well and I noticed unfiltered impacts my lipids. Ugh tradeoffs"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1927061145497559052) 2025-05-26 17:55:54 UTC 24.2K followers, 1124 engagements


"A FFAR2 agonist peptide would be 🔥 FFAR2 inhibits adipocyte lipolysis increases PYY and GLP-1 endogenously would help restore gut barrier function could reduce visceral adipose inflammation and modulate immune function. Or you could just eat more fiber"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948561929339105424) 2025-07-25 01:52:21 UTC 24.2K followers, 2197 engagements


"Proteolytic Toxins Surge Protein-fermenting taxa bloom flooding the lumen with ammonia branched-chain fatty acids p-cresol indoles and hydrogen sulfide compounds that are cytotoxic DNA damaging and genotoxic to colonocytes"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949684525610705153) 2025-07-28 04:13:08 UTC 24.2K followers, XXX engagements


"Yes. Although with some important distinctions. Also I absolutely share your frustration with microbiome research. Butyrate production is extremely important in the colon for many reasons but one of the top reasons is it supplies XX% of ATP to the colonocytes. Butyrate is mainly produced by saccharolytic bacteria in the colon. They ferment fiber to butyrate acetate and propionate. SCFA is acidic so the production or lack thereof is the primary driver of colonic pH. pH is the driver of what genera live and which ones dominate. In higher pH proteolytic genera are favored and in the instance of"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949131922548093175) 2025-07-26 15:37:18 UTC 24.2K followers, XXX engagements


"Analyzing Fiber Patterns of the Hadza So the Hadza dont really eat any fiber but they do drink 2-3L of fermented milk. They eat loads of saturated fat yet have very low chronic disease. They dont have much CVD but they do have measured plaque buildup. Fermented milk contains SCFA which is acetate dominant. It is hard to determine an exact fiber equivalent since its all exogenous. 1g of fermentable fiber yields 0.6g of SCFA. 3L of fermented milk would yield about 3.2-4.0g of type X fiber but yields mostly acetate. The remainder of their SCFAs likely come from mucin which would be about 10mmol"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949267917239177720) 2025-07-27 00:37:41 UTC 24.2K followers, 2770 engagements


"There isnt a single thing you could eat that does more than fiber. And ironically its the one thing you dont technically need to survive"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1947683263084171717) 2025-07-22 15:40:50 UTC 24.2K followers, 44K engagements


"My toxic trait is if I find a rabbit hole I cant help but jump down it"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949146799220166861) 2025-07-26 16:36:24 UTC 24.2K followers, 3360 engagements


"The more neutral pH/low oxygen environment of the gut makes it perfect for pathogens. With the gut barrier integrity compromised and pathogens like C. rodentium Salmonella and others expand rapidly. This triggers epithelial inflammation and systemic disease"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949684493574701374) 2025-07-28 04:13:01 UTC 24.2K followers, 1141 engagements


"We werent meant to snack all day. Oh really Hadza men graze constantly while hunting. Berries baobab honey whatever they find. By the time theyre back theyve eaten XX% of their calories. And they have some of the best metabolic health on Earth. They also move a lot"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1947421029678387649) 2025-07-21 22:18:49 UTC 24.2K followers, 31.1K engagements


"@hybridathlete8 What if it is grass fed Himalayan yak butter grazed at XX ft blessed by virgin monks and mixed with coffee and shilajit. Is unlimited OK there"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949483026527957189) 2025-07-27 14:52:27 UTC 24.2K followers, XXX engagements


"I think what may be difficult to determine is a single cause. It could be a combination of factors that make it difficult to fuse table or associated a single cause. I think the root cause is caloric flux but then describing in broad trends whats caused that is likely multifactorial. - Decreased exercise - Increase reliance on processed food - More processed food means less fermentable fiber - Less fermentable fiber means less SCFA - Less SCFA means less FFAR2 signaling which then means less endogenous GLP-1/PYY increased insulin resistance less hormonal satiation increased adiposity -"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1948865264965353803) 2025-07-25 21:57:41 UTC 24.2K followers, XX engagements


"@eddycurran @lebosquet Yes. Plant diversity plays a role for sure. What I dont know is how big of a role. Is it just fiber diversity or is it fiber diversity + unique plant compounds I do know the Hadza eat about XXX unique plants a year"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949373361425158431) 2025-07-27 07:36:41 UTC 24.2K followers, XXX engagements


"@nntaleb Couldnt agree more. Theres also a risk of upregulation of glycolic reliance"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1947411965124755478) 2025-07-21 21:42:48 UTC 24.2K followers, 7679 engagements


"@ManjelievskaiaJ Thats so cool. Was it a vintage find"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1949555993387626510) 2025-07-27 19:42:24 UTC 24.2K followers, XX engagements


"Circadian rhythm governs the SCN or master clock. Incredibly important. But its not the only clock we have. We have other peripheral clocks. SCN signals these peripheral clocks but they also respond to independent stimuli such as food. 👇"  
![@gregmushen Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::14200022.png) [@gregmushen](/creator/x/gregmushen) on [X](/post/tweet/1947804334588367114) 2025-07-22 23:41:56 UTC 24.2K followers, 9912 engagements

[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

@gregmushen Avatar @gregmushen Greg Mushen

Greg Mushen posts on X about colon, carnivore, drops, protocol the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXX engagements in the last XX hours.

Engagements: XXXXX #

Engagements Line Chart

  • X Week XXXXXXX +44%
  • X Month XXXXXXX +79%
  • X Months XXXXXXXXX -XX%
  • X Year XXXXXXXXXX +2,758%

Mentions: XX #

Mentions Line Chart

  • X Week XXX -XXXX%
  • X Month XXX +123%
  • X Months XXX +60%
  • X Year XXX +303%

Followers: XXXXXX #

Followers Line Chart

  • X Week XXXXXX +0.85%
  • X Month XXXXXX +2.30%
  • X Months XXXXXX +23%
  • X Year XXXXXX +92%

CreatorRank: XXXXXXX #

CreatorRank Line Chart

Social Influence #


Social category influence celebrities XXXX% musicians XXXX%

Social topic influence colon 1.72%, carnivore 1.72%, drops 0.86%, protocol 0.86%, dolly parton 0.86%, beta 0.86%, gum 0.86%, bananas 0.86%, dna 0.86%, surge XXXX%

Top accounts mentioned or mentioned by @davidgmillsatty @arteesun @lebosquet @ultimape @veganchristian3 @bowtiedgatordds @tuckergoodrich @nutrivorec @xdb500 @drbreteho @jcdfitness @manjelievskaiaj @nutridetect @coffeeblackmd @bowtiedhrt @william_chris2p @tuluminati888 @gregnotsure @drryanpdaly @bwhite4363

Top Social Posts #


Top posts by engagements in the last XX hours

"What happens to gut health on Keto/Carnivore Can you still have a health gut"
@gregmushen Avatar @gregmushen on X 2025-07-26 01:58:16 UTC 24.2K followers, 14.2K engagements

"Branched SCFA (BCFA) BCFA is a marker of protein fermentation. While it is similar chemically to SCFA but a weak agonist of FFAR2 The problem is BCFA arent a harmless byproduct. They are associated with ammonia p-cresol and biogenic amines. They are potentially cytotoxic and pro inflammatory to colonocytes"
@gregmushen Avatar @gregmushen on X 2025-07-26 01:58:27 UTC 24.2K followers, 1193 engagements

"Summary - Butyrate drops XX percent - Colonocytes starve and trigger autophagy - BHB is not butyrate - Colon pH rises favoring proteolytic bacteria - Branched chain SCFA ammonia and ImP increase - Mucin fermentation cannot keep up - Zonulin rises the barrier breaks"
@gregmushen Avatar @gregmushen on X 2025-07-26 01:58:28 UTC 24.2K followers, 1089 engagements

"SCFAs such a butyrate are produced primarily from fermentable fiber in the gut. On diets like carnivore there can still be SCFA production but its suboptimal and comes at a cost. - collagen can produce SCFA via proteolytic fermentation of amino acids - bile acid resistant microbiata can flourish but this can lead to imbalance - Akkermansia muciniphila can ferment mucins from the gut lining but this comes at the cost of long term barrier integrity - fermented meats and cheeses can be added. The Masai would do it this way by drinking tons of fermented milk - Supplements - either through"
@gregmushen Avatar @gregmushen on X 2025-07-18 19:19:30 UTC 24.2K followers, 2514 engagements

"Whos one person living or dead youd like to see on X Ill go first"
@gregmushen Avatar @gregmushen on X 2025-07-21 14:26:42 UTC 24.2K followers, 3933 engagements

"Since butyrate production is low there is a fallback mechanism: mucin or the gut lining. Some butyrate is needed for ATP for colonocytes. Colonocytes get around XX% of their ATP from butyrate. Taxa such as Akkermansia can ferment mucin to butyrate"
@gregmushen Avatar @gregmushen on X 2025-07-28 04:12:59 UTC 24.2K followers, 1269 engagements

"This was the protocol PJ used. The Xs contain things that were in the protocol that he didnt use. Circles are things he did. Your doctor is right. Even with this we dont know it works. We dont know even if its lower if itll lead to better outcomes. My hypothesis is that it might be but its experimental wildly unproven and should just be interpreted as an n=2. Note that these compounds have risks and always talk to a doctor. While some of these are generally regarded as safe we dont know the impacts of stacking them. In other words talk to a doctor before you take any changes to make sure its"
@gregmushen Avatar @gregmushen on X 2025-04-29 20:50:39 UTC 24.2K followers, XXX engagements

"I referenced about five studies so let me know which one and I can do a more detailed breakdown. But to summarize them altogether - we know which taxa we need - we know what pH we roughly need to have those - carnivore since it lacks fiber will be at a much higher pH - higher pH will mean more proteolytic taxa - fiber is needed to bring ph down"
@gregmushen Avatar @gregmushen on X 2025-07-23 13:30:31 UTC 24.2K followers, XX engagements

"Pathogens and inflammatory tone Higher pH oxygen leakage and nitrate favor Proteobacteria as mentioned (E. coli Salmonella). Their LPS and flagellin sustain a low grade inflammatory tone and metabolic endotoxemia"
@gregmushen Avatar @gregmushen on X 2025-07-28 04:13:10 UTC 24.2K followers, XXX engagements

"Common misconception. Gluconeogensis is demand driven not supply driven"
@gregmushen Avatar @gregmushen on X 2025-07-24 00:29:15 UTC 24.2K followers, 14.4K engagements

"How To Construct a Fiber Heavy Tsimane Diet To get 70g of fiber and 55g of resistant starch this is what a day of eating would look like: - 350g green plantain (boiled and cooled) - 400g red potato (cooked and cooled) - 300g jasmine rice (cooked and cooled) - 250g pinto beans (pressure cooked) - 150g of blueberries - 200g of mixed vegetables - 30g of raw mixed nuts - 390g of chicken - X tbsp of olive oil Macros Calories: 2665 Protein: 161g Carbohydrate: 347g Fat: 43g Fiber: 70g Resistant starch: 55g This would be a propionate rich SCFA profile like the Tsimane"
@gregmushen Avatar @gregmushen on X 2025-07-27 00:58:30 UTC 24.2K followers, 16.4K engagements

"Italian food is just roman-mesoamerican fusion"
@gregmushen Avatar @gregmushen on X 2025-07-29 03:25:57 UTC 24.2K followers, XXX engagements

"@ManjelievskaiaJ Oh cool. Wouldnt have expected that to be at a Dolly Parton gift shop"
@gregmushen Avatar @gregmushen on X 2025-07-27 20:17:56 UTC 24.2K followers, XX engagements

"The more I look into the microbiome and what it responds to the more it makes me think that most of the plants we evolved to eat are lost. The fibers are microbiome responds to well appear to be somewhat rare. Green bananas chicory root plantains guar gum acacia inulin from tubers beta glucan from oats. These resemble wild like plants bark roots unripe starches cooked starches that were roasted on a fire to be edible and then later cooled rhizomes (tumeric ginger galangal etc.) etc. Could explain both why some people dont do well on fiber and also why just adding more fiber without the"
@gregmushen Avatar @gregmushen on X 2025-07-26 19:33:48 UTC 24.2K followers, 18.8K engagements

"Can you still get all your nutrients from food A common belief is that our food supply is too depleted and that hitting all your micros from food alone is nearly impossible. That can be true if youre not tracking micros and not being intentional with your food selection. But if you do track and build your meals around nutrient density its absolutely possible. Personally Ive been tracking my micronutrients and consistently hitting all targets from food alone except for vitamin D (VDR polymorphism and low light Seattle) and B vitamins (MTRR polymorphism). My go to for magnesium is a daily"
@gregmushen Avatar @gregmushen on X 2025-06-08 17:46:27 UTC 24.2K followers, 31.7K engagements

"@CoffeeBlackMD Haha. True. I was too lazy to make filtered coffee as well and I noticed unfiltered impacts my lipids. Ugh tradeoffs"
@gregmushen Avatar @gregmushen on X 2025-05-26 17:55:54 UTC 24.2K followers, 1124 engagements

"A FFAR2 agonist peptide would be 🔥 FFAR2 inhibits adipocyte lipolysis increases PYY and GLP-1 endogenously would help restore gut barrier function could reduce visceral adipose inflammation and modulate immune function. Or you could just eat more fiber"
@gregmushen Avatar @gregmushen on X 2025-07-25 01:52:21 UTC 24.2K followers, 2197 engagements

"Proteolytic Toxins Surge Protein-fermenting taxa bloom flooding the lumen with ammonia branched-chain fatty acids p-cresol indoles and hydrogen sulfide compounds that are cytotoxic DNA damaging and genotoxic to colonocytes"
@gregmushen Avatar @gregmushen on X 2025-07-28 04:13:08 UTC 24.2K followers, XXX engagements

"Yes. Although with some important distinctions. Also I absolutely share your frustration with microbiome research. Butyrate production is extremely important in the colon for many reasons but one of the top reasons is it supplies XX% of ATP to the colonocytes. Butyrate is mainly produced by saccharolytic bacteria in the colon. They ferment fiber to butyrate acetate and propionate. SCFA is acidic so the production or lack thereof is the primary driver of colonic pH. pH is the driver of what genera live and which ones dominate. In higher pH proteolytic genera are favored and in the instance of"
@gregmushen Avatar @gregmushen on X 2025-07-26 15:37:18 UTC 24.2K followers, XXX engagements

"Analyzing Fiber Patterns of the Hadza So the Hadza dont really eat any fiber but they do drink 2-3L of fermented milk. They eat loads of saturated fat yet have very low chronic disease. They dont have much CVD but they do have measured plaque buildup. Fermented milk contains SCFA which is acetate dominant. It is hard to determine an exact fiber equivalent since its all exogenous. 1g of fermentable fiber yields 0.6g of SCFA. 3L of fermented milk would yield about 3.2-4.0g of type X fiber but yields mostly acetate. The remainder of their SCFAs likely come from mucin which would be about 10mmol"
@gregmushen Avatar @gregmushen on X 2025-07-27 00:37:41 UTC 24.2K followers, 2770 engagements

"There isnt a single thing you could eat that does more than fiber. And ironically its the one thing you dont technically need to survive"
@gregmushen Avatar @gregmushen on X 2025-07-22 15:40:50 UTC 24.2K followers, 44K engagements

"My toxic trait is if I find a rabbit hole I cant help but jump down it"
@gregmushen Avatar @gregmushen on X 2025-07-26 16:36:24 UTC 24.2K followers, 3360 engagements

"The more neutral pH/low oxygen environment of the gut makes it perfect for pathogens. With the gut barrier integrity compromised and pathogens like C. rodentium Salmonella and others expand rapidly. This triggers epithelial inflammation and systemic disease"
@gregmushen Avatar @gregmushen on X 2025-07-28 04:13:01 UTC 24.2K followers, 1141 engagements

"We werent meant to snack all day. Oh really Hadza men graze constantly while hunting. Berries baobab honey whatever they find. By the time theyre back theyve eaten XX% of their calories. And they have some of the best metabolic health on Earth. They also move a lot"
@gregmushen Avatar @gregmushen on X 2025-07-21 22:18:49 UTC 24.2K followers, 31.1K engagements

"@hybridathlete8 What if it is grass fed Himalayan yak butter grazed at XX ft blessed by virgin monks and mixed with coffee and shilajit. Is unlimited OK there"
@gregmushen Avatar @gregmushen on X 2025-07-27 14:52:27 UTC 24.2K followers, XXX engagements

"I think what may be difficult to determine is a single cause. It could be a combination of factors that make it difficult to fuse table or associated a single cause. I think the root cause is caloric flux but then describing in broad trends whats caused that is likely multifactorial. - Decreased exercise - Increase reliance on processed food - More processed food means less fermentable fiber - Less fermentable fiber means less SCFA - Less SCFA means less FFAR2 signaling which then means less endogenous GLP-1/PYY increased insulin resistance less hormonal satiation increased adiposity -"
@gregmushen Avatar @gregmushen on X 2025-07-25 21:57:41 UTC 24.2K followers, XX engagements

"@eddycurran @lebosquet Yes. Plant diversity plays a role for sure. What I dont know is how big of a role. Is it just fiber diversity or is it fiber diversity + unique plant compounds I do know the Hadza eat about XXX unique plants a year"
@gregmushen Avatar @gregmushen on X 2025-07-27 07:36:41 UTC 24.2K followers, XXX engagements

"@nntaleb Couldnt agree more. Theres also a risk of upregulation of glycolic reliance"
@gregmushen Avatar @gregmushen on X 2025-07-21 21:42:48 UTC 24.2K followers, 7679 engagements

"@ManjelievskaiaJ Thats so cool. Was it a vintage find"
@gregmushen Avatar @gregmushen on X 2025-07-27 19:42:24 UTC 24.2K followers, XX engagements

"Circadian rhythm governs the SCN or master clock. Incredibly important. But its not the only clock we have. We have other peripheral clocks. SCN signals these peripheral clocks but they also respond to independent stimuli such as food. 👇"
@gregmushen Avatar @gregmushen on X 2025-07-22 23:41:56 UTC 24.2K followers, 9912 engagements

@gregmushen
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