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![gregmushen Avatar](https://lunarcrush.com/gi/w:24/cr:twitter::14200022.png) Greg Mushen [@gregmushen](/creator/twitter/gregmushen) on x 24.2K followers
Created: 2025-07-26 01:58:27 UTC

Branched SCFA (BCFA)

BCFA is a marker of protein fermentation. While it is similar chemically to SCFA, but a weak agonist of FFAR2

The problem is BCFA aren’t a harmless byproduct. They are associated with ammonia, p-cresol, and biogenic amines.

They are potentially cytotoxic and pro inflammatory to colonocytes.

![](https://pbs.twimg.com/media/Gwv5vHUboAAcheM.jpg)

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