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[@bryan_johnson](/creator/twitter/bryan_johnson)
"Dont choke your partner during sex. A study tested XX college-aged women: half had been choked during sex 4+ times in the past month the other half hadnt. Women who were frequently choked had significantly higher levels of S100B (brain injury marker p = .002). This marker is often elevated in people with concussion brain swelling or blood-brain barrier damage. Here its elevated after repeated sexual strangulation"  
[X Link](https://x.com/bryan_johnson/status/1942650385774305508) [@bryan_johnson](/creator/x/bryan_johnson) 2025-07-08T18:21Z 662.6K followers, 2.9M engagements


"Defeating death would be humanity's greatest accomplishment"  
[X Link](https://x.com/bryan_johnson/status/1960742139366924737) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-27T16:32Z 662.6K followers, 3M engagements


"A single night of X hour sleep can drop insulin sensitivity by up to 25%. Your body handles carbs worse stores more fat and spikes glucose longer. Chronic poor sleep can lead to prediabetes. What to do: + Prioritize 7.5+ hrs of sleep + Eat earlier (at least X hrs before bed) + No coffee X hours before bed + No heavy exercise X hours before bed + Keep your room dark and cool + Avoid blue light and screens XX hrs before sleep"  
[X Link](https://x.com/bryan_johnson/status/1973215541419458696) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T02:37Z 662.6K followers, 377.4K engagements


"Going on a date and considering activities. What vibe should I hit + electrolyte mocktails + red light rave before 6pm + cooking with glucose monitors + holding hands during a blood draw + testing blood types to see if were compatible"  
[X Link](https://x.com/bryan_johnson/status/1973946860835344685) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-03T03:03Z 662.6K followers, 204.4K engagements


"Here is some motivation to never eat McDonalds again. Scientific studies link ingredients like trans fats AGEs and high sugar loads to increased risk of heart disease cancer and metabolic dysfunction. 1) The burgers and fries are loaded with trans fats aldehydes and advanced glycation products (AGEs) which are associated with increasing the risk of heart disease and cancer while accelerating aging throughout your body. 2) TBHQ a preservative used in their frying oils has been described in laboratory and animal studies as a DNA-damaging compound that can suppress immune cell activity. While"  
[X Link](https://x.com/bryan_johnson/status/1974594262298927113) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-04T21:55Z 662.6K followers, 78.8K engagements


"There's now an active betting market on @Polymarket for my nighttime erections. A few things to consider when making your wager: + I return from China on the 16th of Dec and measurement will take place during the final week of the month. I've not previously measured how much international travel affects NTE however I know from casual observation that it significantly decreases them. The body get's pretty messed up with such a large time zone change. It's TBD how long it takes my body to adjust normal NTE. + My baseline NTE measurement was two hours and XX minutes (ave for a XX yr old). My"  
[X Link](https://x.com/bryan_johnson/status/1866608220128809402) [@bryan_johnson](/creator/x/bryan_johnson) 2024-12-10T22:17Z 662.5K followers, 1.1M engagements


"Brush your teeth immediately when you wake up. Overnight your mouth fills with acid-producing bacteria due to lower salivary flow. When you eat or drink carbs or sugars without brushing first you feed this bacteria which immediately producing acids acidity increases beyond the tolerance threshold and immediately starts damaging your enamel. Also an epidemiological 2010 study linked poor oral hygiene to higher levels of systemic inflammation and increased cardiovascular risk due to the spread of oral pathogens into the bloodstream. A 2020 nationwide study in Korea following 161286 subjects for"  
[X Link](https://x.com/bryan_johnson/status/1937641637091639568) [@bryan_johnson](/creator/x/bryan_johnson) 2025-06-24T22:39Z 662.5K followers, 1.3M engagements


"0/ What the product has: + X biomimetic peptides more than any other product. And in the highest concentrations. + We put every peptide in its own patented delivery system so it reaches the exact receptor its designed to target for maximum impact. + We integrated patented nanofluorosome technology that is activated by the Blueprint Laser Cap (avail in Sept). The serum is water-based lightweight and dries completely residue free. Layers of interventions and actives stacked upon each other"  
[X Link](https://x.com/bryan_johnson/status/1958233603495883205) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-20T18:24Z 662.6K followers, 132.2K engagements


"This is big. OpenAI and Retro used a custom model to make cellular reprogramming into stem cells XX better faster and safer. Similar Wright brothers glider to a jet engine overnight. We may be the first generation who won't die. Let's take a look at what they did. 🧵"  
[X Link](https://x.com/bryan_johnson/status/1962217985931874429) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-31T18:16Z 662.6K followers, 976.3K engagements


"MDMA is different from addictions like + social media + notifications + on-demand streaming + fast food + sugar + porn MDMA promotes shared connection over instant gratification. Its signature is oxytocin not just dopamine. A study showed MDMA increased emotional empathy happiness and social behavior. Empathy was measured using the Multifaceted Empathy Test (MET). The study included XX healthy young adults (16 women XX men age 20-31) given a single dose of MDMA (125 mg). This was all done with medical supervision. Kids dont try this at home"  
[X Link](https://x.com/bryan_johnson/status/1963346029203603596) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-03T20:59Z 662.6K followers, 456.5K engagements


"Im going to trial PEMF. Exploring if it will boost my vascular function blood flow performance and bone health. Here is my protocol and what I expect to achieve. 🧵"  
[X Link](https://x.com/bryan_johnson/status/1963652824111485232) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-04T17:18Z 662.5K followers, 115.8K engagements


"Most builders fail to understand that they are cognition athletes. They compete on intellect. Yet they live life ruining their brain power with poor sleep and nutrition and little exercise. So simple yet so counterintuitive of todays twisted norms"  
[X Link](https://x.com/bryan_johnson/status/1973398660332335395) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T14:44Z 662.5K followers, 869.4K engagements


"A new longevity stem cell therapy in monkeys showed an estimated XX yrs of biological age reversal across XX% of tissues. Scaled cautiously to humans could correspond to XXX years of rejuvenation. If this replicates it's a big deal. 🧵"  
[X Link](https://x.com/bryan_johnson/status/1974107386827977011) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-03T13:40Z 662.5K followers, 285.5K engagements


"my updated morning routine 5-10am in bed 8:30 pm + X hrs restorative sleep + X to X wake events + sleep stress X% wake up standing tall water pik floss brush teeth apply blueprint hair serum wear red light cap X min while. getting 10000 lux light in eyes shower + shampoo hair + use blueprint scalp treatment breakfast blueprint stack + longevity mix + X pills + protein collagen peptides evoo creatine berries XX min exercise (cardio strength flexibility balance) XX min dry sauna 200F w/ ice on boys X min red/nir light therapy X J/cm XX min Intermittent HypoxicHyperoxic Training (IHHT) XX min"  
[X Link](https://x.com/bryan_johnson/status/1974527667707011380) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-04T17:30Z 662.6K followers, 349.3K engagements


"MDMA increased oxytocin levels 10-30x. Increasing friendliness and sociability for X hours. Study was XX healthy volunteers. XXX mg dose"  
[X Link](https://x.com/bryan_johnson/status/1975978895200674283) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-08T17:37Z 662.6K followers, 410.4K engagements


"My daily intake of high quality plant proteins provides a complete spectrum of essential amino acids with methionine as the only intentional exception. This enables partial methionine restriction a strategy supported by evidence linking modest reductions in methionine intake to enhanced metabolic health and potential longevity benefits. I obtain the remainder of my protein from collagen peptides and whole food sources bringing my total daily intake to approximately XXX g (1.6 g/kg/day) which is the upper range shown to maximize muscle protein synthesis and metabolic function without"  
[X Link](https://x.com/bryan_johnson/status/1976344638161367448) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-09T17:50Z 662.6K followers, 38.9K engagements


"Will you thrive or die with AGI Take this test. AI is advancing fast. Faster than any technology shift in history. Electricity took XX years to reach mass adoption. The smartphone XX. ChatGPT reached XXX million in two months. Studies show that humans handle incremental change well but struggle with exponential change because our brains have evolved for linear prediction. Were probing at this situation when we ask: will AI take my job No one knows the answer to this question. What we do know: change is happening and it could be more radical than we can imagine. The question is: will you be"  
[X Link](https://x.com/bryan_johnson/status/1977076353263714479) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-11T18:18Z 662.6K followers, 193.1K engagements


"Most of the hate I get is understandable. Wealthy guy doing unusual things for health. Looks weird. Acts weird. Says weird things. Ok. Theres also something else going on. Ultraprocessed foods emerged in the 1970s. Those in adolescence / early adulthood (now 50-64) exposed to these foods now have nearly 2x the food addiction rates than the generation immediately preceding them (now 65-80). More than half of U.S. calories now come from ultra-processed foods: XX% for adults and XX% for youth. Contending only with tobacco and ultra-processed foods now seems quaint. In recent decades the most"  
[X Link](https://x.com/bryan_johnson/status/1977139591280050561) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-11T22:29Z 662.6K followers, 858.7K engagements


"Updates this past week: + 9th week of cycling metformin (currently in off stage) + exploring a psilocybin protocol for longevity + 5th week of PEMF therapy + exploring harvesting my cells iPSCs organoids + sent out urine for heavy metals testing + waiting for my semen microplastic results + 2nd week of peptides: SLU + SS-31 tirzepitide cerebrolysin"  
[X Link](https://x.com/bryan_johnson/status/1977888331582128323) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-14T00:05Z 662.6K followers, 146.8K engagements


"@PeterSchiff Peter waking up and checking your phone fractures sleep integrity. The blue light and cognitive arousal suppress melatonin elevate cortisol and reset circadian timing by XX to XX min. Lowering your willpower and metabolic regulation the following day"  
[X Link](https://x.com/bryan_johnson/status/1978463469830586482) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T14:10Z 662.6K followers, 121.3K engagements


"Your testosterone plummets when you miss sleep. When healthy young men were restricted to X hours of sleep per night for X nights their daytime testosterone levels fell by 1015% (compared with a rested condition)"  
[X Link](https://x.com/bryan_johnson/status/1978575024807182490) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T21:33Z 662.6K followers, 71K engagements


"People are confused by me and my intentions. Im called a narcissist a tech bro vampire grifter and health freak. Let me be clear about what Im doing: my goal is to build the worlds next major moral framework. An ideology that bridges human and machine biology and intelligence the ancient and the emergent. The coming psychosis A real possibility in the coming years is that society becomes dangerously psychotic. Yes we are already psychotic. Addicted fragmented and self-destructive. But I mean clinically psychotic and on a civilizational scale. We are already showing precursor symptoms: record"  
[X Link](https://x.com/bryan_johnson/status/1979631886415880350) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-18T19:33Z 662.6K followers, 366.2K engagements


"What are you listening to today"  
[X Link](https://x.com/bryan_johnson/status/1810044975331315987) [@bryan_johnson](/creator/x/bryan_johnson) 2024-07-07T20:15Z 661.9K followers, 77.2K engagements


"To everyone offering me ill will I offer you goodwill in return"  
[X Link](https://x.com/bryan_johnson/status/1877021219708412114) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-08T15:55Z 661.9K followers, 507.8K engagements


"I don't eat red meat. This is why. You can eat meat. I'm cool with that"  
[X Link](https://x.com/bryan_johnson/status/1880016353731719643) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-16T22:16Z 662.2K followers, 1.7M engagements


"My life is so bizarre. I go around trying to convince people that dying is dumb and get called a weird motherfucker"  
[X Link](https://x.com/bryan_johnson/status/1899511346976448810) [@bryan_johnson](/creator/x/bryan_johnson) 2025-03-11T17:22Z 662K followers, 1.6M engagements


"Today plan your week out: . what time you'll go to bed . when you'll turn off screens . the days you'll exercise Then achieve XXX% of your goals and be proud of yourself"  
[X Link](https://x.com/bryan_johnson/status/1911419565772320792) [@bryan_johnson](/creator/x/bryan_johnson) 2025-04-13T14:01Z 661.6K followers, 231.9K engagements


"Your body wants to prevent aging but is too busy digesting that late night snack"  
[X Link](https://x.com/bryan_johnson/status/1952123039405285518) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-03T21:42Z 661.9K followers, 328.8K engagements


"if our food isn't trying to kill us then explain radioactive shrimp"  
[X Link](https://x.com/bryan_johnson/status/1962992430350737848) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-02T21:34Z 661.7K followers, 77.3K engagements


"My 4+ hour daily routine resets my blood vessels to perform like they did in my teenage years. 🧵"  
[X Link](https://x.com/bryan_johnson/status/1963317382547739092) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-03T19:05Z 662.2K followers, 118.9K engagements


"Don't Die right now is the world's largest ideology"  
[X Link](https://x.com/bryan_johnson/status/1969486892526981330) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-20T19:40Z 662.1K followers, 133.8K engagements


"If you're depressed or anxious do this: X. asleep at the same time every day X. final meal/snack X hrs before bed X. screens off XX before bed X. eliminate all processed sugars X. exercise every day"  
[X Link](https://x.com/bryan_johnson/status/1970180520450629751) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-22T17:36Z 662K followers, 381.5K engagements


"its freaky friday. who do I swap lives with"  
[X Link](https://x.com/bryan_johnson/status/1971730757619273798) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-27T00:17Z 661.5K followers, 120.1K engagements


"@ZbynekDrab they want you to be in service of the King"  
[X Link](https://x.com/bryan_johnson/status/1975682936075919813) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-07T22:01Z 661.9K followers, 20.7K engagements


"@jeligooch Heres the reasoning and data"  
[X Link](https://x.com/bryan_johnson/status/1977922552812228668) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-14T02:20Z 661.6K followers, 4312 engagements


"@thegnars_eth you are forgiven this shall pass and you have learned"  
[X Link](https://x.com/bryan_johnson/status/1978482344131727512) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T15:25Z 661.9K followers, 25.9K engagements


"this person is impaired by sleep deprivation"  
[X Link](https://x.com/bryan_johnson/status/1839756357404438905) [@bryan_johnson](/creator/x/bryan_johnson) 2024-09-27T19:57Z 662.5K followers, 701K engagements


"My HBOT protocol: . session XX today (60 total) . total time in chamber 4470 min . X ATA . XX min XXX% oxygen X min break . chamber by @hpotech_medical . will complete post therapy measurements this thursday . my max HR has increased by 15%"  
[X Link](https://x.com/bryan_johnson/status/1878183234225545545) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-11T20:52Z 662.5K followers, 341.8K engagements


"a lot of people intensely want me to fail and I appreciate all of you who had my back on this"  
[X Link](https://x.com/bryan_johnson/status/1878837839988982254) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-13T16:13Z 662.4K followers, 979.2K engagements


"The future is going to be different than the present and even though I dont know what the future will be it gives me hope"  
[X Link](https://x.com/bryan_johnson/status/1886058897737445602) [@bryan_johnson](/creator/x/bryan_johnson) 2025-02-02T14:27Z 662.4K followers, 84.2K engagements


"When AI can think better than you in every way what are you going to think about"  
[X Link](https://x.com/bryan_johnson/status/1898770841653170403) [@bryan_johnson](/creator/x/bryan_johnson) 2025-03-09T16:20Z 662.5K followers, 394.9K engagements


"You can start your party at X pm instead of X pm and be just as cool"  
[X Link](https://x.com/bryan_johnson/status/1900542364948578606) [@bryan_johnson](/creator/x/bryan_johnson) 2025-03-14T13:39Z 662.4K followers, 2.7M engagements


"The best advice is to ignore advice. They're just dumping their baggage on you"  
[X Link](https://x.com/bryan_johnson/status/1924258601092452759) [@bryan_johnson](/creator/x/bryan_johnson) 2025-05-19T00:19Z 662.5K followers, 282K engagements


"First I shocked my Johnson and performance improved. Then I shocked my sprained ankle and recovered faster. Now Im shocking my entire body 🧵"  
[X Link](https://x.com/bryan_johnson/status/1924885203497189728) [@bryan_johnson](/creator/x/bryan_johnson) 2025-05-20T17:49Z 662.5K followers, 222.9K engagements


"Before bed tonight read for XXX min. + reduce stress levels by up to XX% + better than music (61%) tea (54%) or walk (42%)"  
[X Link](https://x.com/bryan_johnson/status/1945659290217525757) [@bryan_johnson](/creator/x/bryan_johnson) 2025-07-17T01:38Z 662.4K followers, 768.9K engagements


"resting heart rate before bed is the #1 indicator of great sleep"  
[X Link](https://x.com/bryan_johnson/status/1955429771565003203) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-13T00:42Z 662.5K followers, 122.4K engagements


"Phones carry XX more bacteria than toilet seats. Wipe your screen daily with microfiber and XX% alcohol. This will cut down on bacteria like MRSA or strep that may live on your phone. Its unclear if these bacteria make you ill. Direct infection trials dont exist. But most experts agree that touching fewer germs is a hygiene win"  
[X Link](https://x.com/bryan_johnson/status/1960053862909575620) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-25T18:57Z 662.4K followers, 218.8K engagements


"One of the best new habits I've started lately is calling friends for XX seconds. I'll say hi tease them or share something funny. Then it's immediately over. No lingering. No fuss. It's great"  
[X Link](https://x.com/bryan_johnson/status/1960776685516881924) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-27T18:49Z 662.4K followers, 519.3K engagements


"we ask for longer lives we get labubus"  
[X Link](https://x.com/bryan_johnson/status/1964013121607225577) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-05T17:09Z 662.4K followers, 213.2K engagements


"1/ Every X hour per day spent sitting increases death risk in the next X years by 3%. A Chinese study tracked 17265 participants (ages 42-61) in rural communities and gathered data on their self-reported sitting time. After excluding cases of pre-existing cancer heart disease and deaths occurring within the first year of the study numbers remained elevated: + sitting 4-8 hours/day: +13% increased risk + sitting 8-11 hours/day: +32% increased risk + sitting XX hours/day: +42% increased risk Figures adjusted to account for demographics socioeconomic status and health risk factors like BMI blood"  
[X Link](https://x.com/bryan_johnson/status/1965167481867395438) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-08T21:36Z 662.4K followers, 60.2K engagements


"Ironically happiness is not the fulfillment of your desires but overcoming them"  
[X Link](https://x.com/bryan_johnson/status/1965459676944089292) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-09T16:57Z 662.4K followers, 572.9K engagements


"we both have beef"  
[X Link](https://x.com/bryan_johnson/status/1970228948228546665) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-22T20:49Z 662.4K followers, 121.1K engagements


"owning a dog lowers your risk of death by XX% so i got 12"  
[X Link](https://x.com/bryan_johnson/status/1970900430541684860) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-24T17:17Z 662.4K followers, 265.4K engagements


"The first generation raised on junk food is exhibiting addiction rates comparable to those of drugs and alcohol linked to physical and mental health consequences. The 1970s and 1980s marked a crucial period for the increased prevalence of junk foods (Ultra-Processed Foods UPFs) in the U.S. food supply. Consequently individuals who were children or teenagers during this time (now aged 5064) show nearly double the addiction rates compared to adults aged 6580 according to a nationally representative survey of 2713 U.S. adults aged 5080 Prevalence of food addiction by Age group Age group 50-64:"  
[X Link](https://x.com/bryan_johnson/status/1972736060729012289) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-29T18:51Z 662.5K followers, 37.5K engagements


"@pepijnniesten psychedelics are the closest and many people report breath work and mediation give them a magic altered state"  
[X Link](https://x.com/bryan_johnson/status/1973495788757196993) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T21:10Z 662.5K followers, 37.8K engagements


"Going to bed on time is the most heroic act possible in 2025"  
[X Link](https://x.com/bryan_johnson/status/1976048124688056449) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-08T22:12Z 662.5K followers, 162.5K engagements


"The 22x increase was from introducing sauna HBOT and most recently IHHT. + XX HBOT sessions almost tripled my VEGF (22 XX pg/mL). + XX additional HBOT sessions (total 128) with XX initial sauna sessions increased my VEGF again by XXX more folds (64 XXX pg/mL). + Continued daily sauna for XX more sessions (total 120) XX additional HBOT sessions (total 140) and XX IHHT sessions further boosted my VEGF from XXX pg/dL to its current level of XXX pg/dL"  
[X Link](https://x.com/bryan_johnson/status/1976747894297469189) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T20:33Z 662.4K followers, 5248 engagements


"Esha good decision. Watermelon is XX% cellular structured water replenishing plasma volume enhancing electrolyte balance and supporting renal filtration. Improves vascular elasticity lowers blood pressure and enhances endothelial function. Contains lycopene protecting against oxidative stress and lipid peroxidation in cell membranes. Beta carotene and vitamin C work together to regenerate the bodys antioxidant network. High in magnesium and potassium. Low calorie density activates AMPK promotes fat oxidation and metabolic efficiency. The fiber+polyphenol pairing supports short-chain fatty"  
[X Link](https://x.com/bryan_johnson/status/1977736517700452572) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-13T14:01Z 662.4K followers, 103.2K engagements


"On @netflix Jan X 2025 is the year of dont die"  
[X Link](https://x.com/bryan_johnson/status/1866832888605598099) [@bryan_johnson](/creator/x/bryan_johnson) 2024-12-11T13:10Z 662.6K followers, 6.2M engagements


"0/ How it works Heat exposure in a sauna puts your body under mild stress triggering natural repair processes that improve overall health. Finnish dry saunas specifically use controlled heat to stimulate these beneficial responses including: + Repairing and maintaining proteins (heat shock proteins) + Improving blood flow and relaxing blood vessels + Boosting antioxidant activity + Optimizing metabolism + Enhancing fitness + Reducing inflammation + Strengthening immunity + Recycling and repairing cells (autophagy) All these processes combine to give whole-body health benefits"  
[X Link](https://x.com/bryan_johnson/status/1920216898790412627) [@bryan_johnson](/creator/x/bryan_johnson) 2025-05-07T20:39Z 662.5K followers, 103.9K engagements


"This morning I discovered the towel Ive been taking into the sauna is XX% cotton and XX% polyester. In my effort to detox I've accidentally been rubbing plastic on my body. I hope this brings you some joy"  
[X Link](https://x.com/bryan_johnson/status/1941913033452011800) [@bryan_johnson](/creator/x/bryan_johnson) 2025-07-06T17:32Z 662.5K followers, 1M engagements


"it's my birthday tomorrow"  
[X Link](https://x.com/bryan_johnson/status/1958715629835624899) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-22T02:19Z 662.5K followers, 3.5M engagements


"things ppl will do before going to bed on time: NAD drips exotic peptides cold plunge five day fasts umbilical stem cells just south of the border"  
[X Link](https://x.com/bryan_johnson/status/1970558668723925273) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-23T18:39Z 662.5K followers, 110.4K engagements


"Drinking coffee to keep you awake after XX cancels out all longevity benefits Coffee drinkers live longer but only if you drink it in the morning Morning-only drinkers: + XX% lower risk of death + XX% lower risk of cardiovascular death Compared to non coffee-drinkers If you drink coffee all day theres no clear benefit. This is according to a study of 40725 US adults with a XX year follow-up. Why timing matters: the half-life of caffeine in blood is XX hrs. A X pm cup leaves you with the equivalent of half a cup in your system at X pm. Some are genetically slow metabolizers. Factors like"  
[X Link](https://x.com/bryan_johnson/status/1971616123494998206) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-26T16:41Z 662.5K followers, 280.6K engagements


"Health is forgotten until its the only thing that matters"  
[X Link](https://x.com/bryan_johnson/status/1972674688087445603) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-29T14:47Z 662.6K followers, 335.1K engagements


"The 197080s were the dawn of ultra-processed foods. That generation now shows 2x the addiction rates of the 1950s60s generation. And now showing debilitating health effects. 🧵"  
[X Link](https://x.com/bryan_johnson/status/1972735443142902067) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-29T18:49Z 662.5K followers, 60.3K engagements


"Who's controlling who Your phone is always there in your pocket in the restroom at the stop light. Stealing sleep focus and energy"  
[X Link](https://x.com/bryan_johnson/status/1972786827628249379) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-29T22:13Z 662.5K followers, 152.3K engagements


"fix your posture and youll feel much better about life"  
[X Link](https://x.com/bryan_johnson/status/1973063911504298265) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-30T16:34Z 662.5K followers, 245.9K engagements


"hey rich people you shouldn't be spending more than $50000/yr on top tier health care. Even an all-out at-home clinic like mine is $300k. The most powerful health and longevity therapies available to you are no alcohol finishing eating X hrs before bed screens off XX min before sleep 7+ hours of sleep morning light avoiding junk food eating from the Don't Die food guide and exercising every day. These alone will move the needle more than any IV drip stem cell exosome or any other fancy protocol out there. If you're going to spend money spend it wisely: + Measure your biomarkers + Create a"  
[X Link](https://x.com/bryan_johnson/status/1973463294804701673) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T19:01Z 662.6K followers, 1.6M engagements


"Heavy marijuana users are 4x more likely to die of an opioid or other drug overdose This is according to a study on users diagnosed with Cannabis Use Disorder (CUD). Being hospitalized for CUD showed: + XXX% increase in 5-year all cause mortality risk + XXX% increase in suicide risk increased + XXX% increase in lung cancer death"  
[X Link](https://x.com/bryan_johnson/status/1973513001283018834) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T22:19Z 662.5K followers, 213.2K engagements


"Don't Die food guide"  
[X Link](https://x.com/bryan_johnson/status/1973525267877667239) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T23:07Z 662.5K followers, 137.4K engagements


"My bad posture almost killed me. We discovered that I have genetically narrow internal jugular veins and my posture was cutting off the flow of blood out of my brain and back to my heart. Even with normal jugular veins you may be doing the same by slouching. Studies found that looking down at a XX degree angle puts a XX lb load on your cervical disc. Instead: + hold your screen at eye level especially for long durations + prop up elbows + use a laptop stand or monitor instead of a phone when possible"  
[X Link](https://x.com/bryan_johnson/status/1973797247625408867) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-02T17:08Z 662.6K followers, 236.2K engagements


"Here are some of the effects in more detail. SRCs = are special stem cells engineered with a FOXO3 tweak that makes them resistant to aging WTCs = are the normal wild-type cells without that upgrade Brain + Cortical thickness and volume restored toward youthful levels: SRC up to 5070% vs WTC 1020% (inferred from imaging and figure analysis; not direct author statistics). + Hippocampus sn-transcriptAge: SRC XXX years (WTC not reported). + Cognition: significant improvement with SRC; modest effect with WTC. Blood / Immune + Age-related gene programs reversed: SRC XX% (upregulated) / 30%"  
[X Link](https://x.com/bryan_johnson/status/1974107391676629187) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-03T13:40Z 662.5K followers, 37.1K engagements


"At a recent social gathering someone challenged me to explain why I dont want to die. I told him that I dont need a reason why. Existence requires no defense. To be is its own justification"  
[X Link](https://x.com/bryan_johnson/status/1974126612745761271) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-03T14:57Z 662.5K followers, 108.9K engagements


"Japan has XX centenarians per 100k people The U.S. is XX per 100k What explains the difference"  
[X Link](https://x.com/bryan_johnson/status/1974247038708531314) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-03T22:55Z 662.5K followers, 1.1M engagements


"Testosterone starts dropping by X% per year after age XX in men Testosterone is important for: + building muscle and bone + regulating mood focus and motivation + protecting against fat gain and insulin resistance Low T leads to weak muscles poor sleep brain fog and faster aging Good sleep nutrition and exercise all improve testosterone"  
[X Link](https://x.com/bryan_johnson/status/1975268547254493358) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-06T18:34Z 662.5K followers, 514.9K engagements


"I dont eat meat for two reasons. First scientific evidence paints a path to optimal health without it. Second very soon AI may be as powerful and dominant to us as we are to animals. Its prudent to keep this in mind"  
[X Link](https://x.com/bryan_johnson/status/1976302461431521535) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-09T15:03Z 662.6K followers, 1M engagements


"My VEGF is in the top X% of the healthy population. While VEGF function and signaling are known to decline with age serum VEGF levels do not exhibit a clear age-dependent decline. A study of XX healthy adults aged XX to XX reported serum VEGF levels between XX and XXX pg/mL with an average of XXX pg/mL (145 pg/mL in men and XXX pg/mL in women). Compared to this cohort of healthy blood donors my latest VEGF level is considered elite placing me in the top 1%"  
[X Link](https://x.com/bryan_johnson/status/1976747896268898322) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T20:33Z 662.5K followers, 5084 engagements


"Gene Therapies for VEGF: Modest Results Compared to Lifestyle Interventions These findings have fueled interest in experimental VEGF gene therapies for boosting performance and longevity in addition to their established use in vascular diseases. However studies on plasmid VEGF gene therapy have shown no significant systemic increases despite improving heart perfusion in patients with advanced coronary artery disease. Even viral vectorscurrently too risky for longevity applications due to high complicationsbarely provide a 3-fold increase. This pales in comparison to the results I've achieved"  
[X Link](https://x.com/bryan_johnson/status/1976747900773544317) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T20:33Z 662.6K followers, 34.2K engagements


"I accidentally drank XX grams of sugar testing a microbiome drink (basically a coke). I hope you enjoy"  
[X Link](https://x.com/bryan_johnson/status/1977835385733722253) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-13T20:34Z 662.6K followers, 410.4K engagements


"If this model is accurate it shows that dont die is native to our biology and the first step is to realize its the goal we want to achieve from the molecular to individual to societal level"  
[X Link](https://x.com/bryan_johnson/status/1978183336972693933) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-14T19:37Z 662.6K followers, 140.2K engagements


"My meeting budget: X min - meet someone new XX min - solve a problem XX min - identify + solve a problem Parkinsons law: work expands so as to fill the time available for its completion"  
[X Link](https://x.com/bryan_johnson/status/1978540812955766884) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T19:17Z 662.6K followers, 84.1K engagements


"Each day humanity: + speaks XXX trillion words + types XX trillion words + uses XXX quadrillion muscle movements to collectively generate $XXX billion in economic output"  
[X Link](https://x.com/bryan_johnson/status/1978570365698748606) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T21:15Z 662.6K followers, 70.8K engagements


"Who is the clearest thinker of AI and what it means for the future of human existence"  
[X Link](https://x.com/bryan_johnson/status/1978635763245003185) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-16T01:35Z 662.6K followers, 499.6K engagements


"If youre on the fence about exercising today take the first step and then decide"  
[X Link](https://x.com/bryan_johnson/status/1979564018588344779) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-18T15:03Z 662.6K followers, 66.7K engagements


"@seafairyservant -sauna without ice on the balls -alcohol before sleep -argue with strangers -spike water with forever chemicals"  
[X Link](https://x.com/bryan_johnson/status/1979687149822963771) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-18T23:12Z 662.6K followers, 203.4K engagements


"Bryan Johnson vs XX Skeptics Filming with @jubileemedia today: Ending death must be humanity's #1 goal Sleep should be your top life priority We may be the first generation to not die No one should eat fast food"  
[X Link](https://x.com/bryan_johnson/status/1979971771475661154) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-19T18:03Z 662.6K followers, 109.6K engagements


"The new cartel waging war on institutional death"  
[X Link](https://x.com/bryan_johnson/status/1735094503026118657) [@bryan_johnson](/creator/x/bryan_johnson) 2023-12-14T00:29Z 662.5K followers, 493.2K engagements


"Even if you dont get it your kids will"  
[X Link](https://x.com/bryan_johnson/status/1880351378947862591) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-17T20:27Z 662.5K followers, 325.6K engagements


"Don't Die Certified will be the world's largest and most trusted repository of clean food. Foods will be tested for nutritional label accuracy heavy metals agrochemicals and microplastics. That data will then be on an updated food label. We'll do restaurant certification too. I'm looking for a founder to build this with me. If you want to eat clean food without thinking about it refer to me the most capable founder you know. dd certified will provide consumers with a trusted source of clean foods that they can consume with confidence. Customers will earn rewards for eating dd certified foods."  
[X Link](https://x.com/bryan_johnson/status/1881080636255195495) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-19T20:45Z 662.5K followers, 374.5K engagements


"Nighttime erection data from my 19-year-old son @talmagejohnson_ and me. His duration is two minutes longer than mine. Raise children to stand tall be firm and be upright"  
[X Link](https://x.com/bryan_johnson/status/1882190186723082318) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-22T22:14Z 662.5K followers, 34.6M engagements


"I love this for @karpathy follow his lead"  
[X Link](https://x.com/bryan_johnson/status/1884363982586470604) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-28T22:12Z 662.5K followers, 203.5K engagements


"Exercise for optimal testosterone + weightlifting (3x wk): increase LH & natural testosterone production + HIIT (2-3x wk): bouts of free testosterone increased receptor binding + cardio (3x wk): optimizes metabolism keeps insulin from interfering testosterone production"  
[X Link](https://x.com/bryan_johnson/status/1928523908233441794) [@bryan_johnson](/creator/x/bryan_johnson) 2025-05-30T18:48Z 662.5K followers, 407.5K engagements


"Throw it in the trash. You're not hungry"  
[X Link](https://x.com/bryan_johnson/status/1934374115085033938) [@bryan_johnson](/creator/x/bryan_johnson) 2025-06-15T22:15Z 662.5K followers, 375.5K engagements


"Ive reduced the microplastics in my blood by 93%. In October my blood contained XX particles. My latest sample contained only X particle. This is my best result to date. Only XXX% of tests contain fewer microplastics. This comes from the largest dataset in the world on microplastics in people. Totaling 2663 results. New protocols started since October that may have contributed to this reduction: + Sauna (200 F XX min daily) + Total Plasma Exchange (TPE) + Tried to remove as much plastic from my life as possible"  
[X Link](https://x.com/bryan_johnson/status/1937194358027190637) [@bryan_johnson](/creator/x/bryan_johnson) 2025-06-23T17:01Z 662.5K followers, 1.3M engagements


"I'm making my health protocol available for everyone. AI-first build. Am looking for a SF based CEO and CTO. I handed my health over to an algorithm years ago and it was the best life decision I've made"  
[X Link](https://x.com/bryan_johnson/status/1944827383531573442) [@bryan_johnson](/creator/x/bryan_johnson) 2025-07-14T18:32Z 662.6K followers, 361.5K engagements


"Who is saying something about the future that you think is correct but is not being heard"  
[X Link](https://x.com/bryan_johnson/status/1949116352947777632) [@bryan_johnson](/creator/x/bryan_johnson) 2025-07-26T14:35Z 662.5K followers, 499.9K engagements


"10 McNuggets have XXX g of sodium over XX % of the daily limit. Population data shows each extra gram of salt raises heart-disease risk roughly X %. McNugget batter contains aluminum salts that can supply up to XXX mg aluminum per XX nuggets a dose exceeding the XXX mg/day threshold linked to higher dementia incidence with long term exposure. High-temperature frying in refined oils at high heat generates toxic aldehydes and race trans-fats even after the U.S. trans-fat ban. The oil is stabilized with TBHQ a chemical with genotoxic and carcinogenic effects shown to exacerbate tumors in rodent"  
[X Link](https://x.com/bryan_johnson/status/1951422077397012606) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-01T23:17Z 662.5K followers, 244.9K engagements


"My urine is now blue. Started Methylene Blue today"  
[X Link](https://x.com/bryan_johnson/status/1952859246942666844) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-05T22:28Z 662.5K followers, 2.5M engagements


"hello mtv welcome to my crib"  
[X Link](https://x.com/bryan_johnson/status/1961482859501568439) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-29T17:35Z 662.5K followers, 463.8K engagements


"Hey @ElizabethHolmes yes happy to help you out. This is what I'd eat in prison with the options they give you. Breakfast Quick oats ( cup dry) + almond milk (1 cup) Raisins (1 oz) Almonds (1 oz handful) Lunch (option 1) Brown rice (1 cup cooked) Dried broccoli + veg flakes Tuna (1 can XX g) (limit canned tuna to twice a week due to heavy metal contamination) Olive oil (1 tbsp) Lunch (option 2) Chili with beans (legume proteins and fibers) Shredded beef (optional add once a week) (add only if Lactoferrin or similar iron supplementation is not available) Snack Protein bar Cashews (1 oz) Dinner"  
[X Link](https://x.com/bryan_johnson/status/1964456315092422883) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-06T22:30Z 662.5K followers, 889K engagements


"Weve built politics on hate. Media on outrage. Social media on spectacle. Technology on addiction. Food on poison. Culture on martyrdom. We ingest it non-stop. Its now our biology. Were inmates in our own asylum. Were sleep deprived drunk. At the moment were giving birth to super intelligence. We need Dont Die to make it through this next stage"  
[X Link](https://x.com/bryan_johnson/status/1966563844702232614) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-12T18:05Z 662.5K followers, 238.8K engagements


"I might have to try shrooms (for science)"  
[X Link](https://x.com/bryan_johnson/status/1967656981038240011) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-15T18:29Z 662.5K followers, 339.4K engagements


"master these five habits"  
[X Link](https://x.com/bryan_johnson/status/1968045055899496783) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-16T20:11Z 662.5K followers, 307K engagements


"French fries are linked to type X diabetes. Cutting out X servings a week lowers your risk by 19%. X key findings: X. Each additional X weekly servings (4-6 ounces per serving) of fries were linked to a XX% increased risk of type X diabetes. X. General potato consumption had a X% increase in type X diabetes risk. X. Boiled mashed or baked potatoes showed no association with increased risk"  
[X Link](https://x.com/bryan_johnson/status/1968362346583351648) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-17T17:12Z 662.5K followers, 337.2K engagements


"I consume more extra virgin olive oil than any other food. Olive oil thats high in polyphenols (366 ppm) showed favorable effects on cholesterol markers compared to ones with medium levels of polyphenols (164 ppm) according to a randomized crossover clinical trial. EVOO quality varies dramatically. Just because it says extra virgin gives no information about the actual quality. You want to see a third party lab report that shows high polyphenols among other things. What I consume daily has XXX% more polyphenols than avg olive oil (400 ppm)"  
[X Link](https://x.com/bryan_johnson/status/1968489456031408610) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-18T01:37Z 662.5K followers, 238.5K engagements


"Fertility is down XX% in the past XX years. Whats the solution"  
[X Link](https://x.com/bryan_johnson/status/1969221724886442314) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-20T02:07Z 662.5K followers, 2M engagements


"I wonder why i never get quality sleep"  
[X Link](https://x.com/bryan_johnson/status/1970309391657136410) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-23T02:09Z 662.5K followers, 362.3K engagements


"Can ecstasy save a relationship This study showed it boosted cooperation trust bliss and insight. XXX mg of MDMA (ecstasy) given to XX men in a placebo controlled cross-over trial showed: + XXX% increase in cooperation with trustworthy partners + MDMA helped participants overcome a breach of trust and cooperate with other players again but not with those who showed themselves untrustworthy in previous rounds"  
[X Link](https://x.com/bryan_johnson/status/1970962996689240467) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-24T21:26Z 662.5K followers, 327.1K engagements


"In my 20s with a few young kids and building a start up my sleep was total chaos. My sleep stress was so intense that I'd do wild and dangerous things at night. I'd dream that one of my children was in bed with me and I was accidentally smothering them so I'd jump up and remove all the covers off the bed to liberate them. Only to find out it had been an imagination. The kids were safely in their rooms. Each of my children did have a time where they'd occasionally end up in the bed so my mind had reason to believe it was real. Or that a bookshelf was about to fall and crush one of my children."  
[X Link](https://x.com/bryan_johnson/status/1971206518533161126) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-25T13:33Z 662.5K followers, 263.7K engagements


"Toxic chemicals are used in period underwear and pads. PFAS are toxins linked to chronic diseases endocrine reproductive and hormonal disruption and developmental abnormalities. There is no safe level of PFAS. A new study reported concentrations of PFAS at levels indicating intentional use (100+ parts per million). AKA theyre a feature not a bug. Toxic PFAS were found in: + XX% of reusable period underwear + XX% of reusable period pads One reusable period underwear tested was made of + XXX% PFAS (77000 parts per million). If you prefer reusable hygiene products purchase from a brand making"  
[X Link](https://x.com/bryan_johnson/status/1973435239327473718) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-01T17:10Z 662.5K followers, 100.9K engagements


"Defeating death must be humanitys #1 objective. Big things are happening right now in our small corner of the galaxy. The most important: super intelligence is in the birth canal on planet earth. Companies and countries are racing towards it. The financial military and psychological incentives are so powerful that nothing can stop it. Not regulation not caution not even fear. We humans have a strong bias to think about this development from our self-interested perspective: will we have jobs What will we do with our time Will we and our families be safe Will AI or humans with AI superimpose"  
[X Link](https://x.com/bryan_johnson/status/1974927414234153200) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-05T19:59Z 662.5K followers, 362.9K engagements


"@rickygervais Ricky do these X things: X. final food of the day X hours before bed X. no alcohol X. screens off XX min before bed X. read a book for XX min before bed They will lower your resting heart rate improve your sleep and give you a boost of willpower and give you more energy"  
[X Link](https://x.com/bryan_johnson/status/1975243100546343150) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-06T16:53Z 662.6K followers, 447K engagements


"My home runs on the rhythm of the sun. Lights rarely turn on. Guests find it strange. When darkness falls only red light remains"  
[X Link](https://x.com/bryan_johnson/status/1975270760932647281) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-06T18:43Z 662.5K followers, 316.3K engagements


"I want nothing other than time"  
[X Link](https://x.com/bryan_johnson/status/1975611551051927729) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-07T17:17Z 662.6K followers, 225.9K engagements


"Never eat McDonalds again Most brush it off thinking its inconsequential. An innocent act of occasional indulgence. Whats the matter Wake up. McDonalds is a drive-thru confessional. Its a philosophy of decay + a global religion built on pleasure + trading vitality for comfort + opium for the masses + soothing our pain for a moment + profiting as you bankrupt + a cathedral of end-times They use a clown to mask the manipulation. Toys to disguise the trap. Bright colors to camouflage your decay. It reveals what we have become: creatures who would rather indulge than be alive. At the golden"  
[X Link](https://x.com/bryan_johnson/status/1975661671848026227) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-07T20:37Z 662.5K followers, 1.5M engagements


"GLP-1s reveal what people really want but couldnt"  
[X Link](https://x.com/bryan_johnson/status/1975906234638516330) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-08T12:48Z 662.5K followers, 112.3K engagements


"Omega-3s help muscles recover faster. XX% less soreness at 24h XX% less damage markers post-exercise With EPA/DHA athletes maintained muscle strength and range of motion. Those on placebo lost up to XX% of muscle strength and XX% of range of motion"  
[X Link](https://x.com/bryan_johnson/status/1975913821031284792) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-08T13:19Z 662.5K followers, 280.1K engagements


"I consume 130g of protein daily from flax pea hemp legumes (lentils peas beans) vegetables collagen peptides nuts and seeds"  
[X Link](https://x.com/bryan_johnson/status/1976303958688973247) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-09T15:09Z 662.6K followers, 182.4K engagements


"@benln Good decision Faecal indicator bacteria on indoor floors linked to exterior sidewalk contamination in New York City"  
[X Link](https://x.com/bryan_johnson/status/1976442800301592809) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T00:20Z 662.5K followers, 39.2K engagements


"4/ Keep these two points in mind when monitoring your VEGF Serum vs plasma: make sure you check whether your VEGF is being measured in serum or plasma; serum values are much higher in short because the platelets are the major reservoir for VEGF in circulation. This is because serum is taken after the blood is allowed to clot in the process platelets release their high content of vegf into the serum that does not happen in plasma in which clotting is inhibited and then the sample is centrifuged to separate the cell from liquid compartments. Warning: While beneficial for health and longevity"  
[X Link](https://x.com/bryan_johnson/status/1976747902619074690) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T20:33Z 662.6K followers, 29.4K engagements


"I'm getting hearing aids"  
[X Link](https://x.com/bryan_johnson/status/1977040335214989717) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-11T15:55Z 662.6K followers, 283K engagements


"Julie a good learning experience. These 2050 calories will cause a massive insulin spike followed by a post-meal crash. Increased hunger 3-4 hr later. Your arteries constrict and blood vesselsl stiffen. The nitrites are a group X carcinogen (increased colorectal cancer risk). Acute oxidative stress. Impaired endothelial function by 20-40% for several hours. Gut microbiome will shift towards pro-inflammatory Firmicutes an obesity-like profile. The dopamine spike from fat+sugar+salt mimics an addiction reward pathway. Repeated will desensitize dopamine receptors causing you to escalate"  
[X Link](https://x.com/bryan_johnson/status/1977085040531324973) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-11T18:53Z 662.5K followers, 210.9K engagements


"@AutismCapital what will you say at my eulogy"  
[X Link](https://x.com/bryan_johnson/status/1977838501199815145) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-13T20:46Z 662.6K followers, 37K engagements


"Am at a hotel. At midnight while in deep sleep someone walks in turns on all lights. Alarming. Its a hotel guest oh weird they gave me this room. Im discombobulated. Turned over and went back to sleep. If I die at least itll be with optimal melatonin production"  
[X Link](https://x.com/bryan_johnson/status/1978476344855216254) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T15:01Z 662.6K followers, 369K engagements


"@MuldoonMartin chaining the door is now part of the protocol"  
[X Link](https://x.com/bryan_johnson/status/1978477171569238167) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T15:04Z 662.6K followers, 30K engagements


"This is remarkable: AI generated a novel cancer fighting hypothesis and labs confirmed. The model demonstrated fluency in the language of human biology. Listening to what cells were saying understanding their context and talking back with a new idea that nature validated"  
[X Link](https://x.com/bryan_johnson/status/1978585079929876674) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T22:13Z 662.6K followers, 546.8K engagements


"confession time. what was your last debaucherous act this is a safe space"  
[X Link](https://x.com/bryan_johnson/status/1979325423529136456) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-17T23:15Z 662.6K followers, 214.8K engagements


"@caloriesproper2 post consumption what would you rate it 1-5"  
[X Link](https://x.com/bryan_johnson/status/1979333503763517771) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-17T23:47Z 662.6K followers, 10.7K engagements


"@NakaSompo you are forgiven as you have learned carry forward"  
[X Link](https://x.com/bryan_johnson/status/1979335027973591491) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-17T23:53Z 662.6K followers, 9082 engagements


"haters what's your beef with me"  
[X Link](https://x.com/bryan_johnson/status/1877033945444782198) [@bryan_johnson](/creator/x/bryan_johnson) 2025-01-08T16:45Z 662.6K followers, 1.7M engagements


"Moved my office into my hyperbaric oxygen chamber"  
[X Link](https://x.com/bryan_johnson/status/1893010094251745351) [@bryan_johnson](/creator/x/bryan_johnson) 2025-02-21T18:49Z 662.6K followers, 16.4M engagements


"Avoid high intensity exercise X hours before sleep. It impairs sleep and recovery according to a new study. Study (from @WHOOP) found that late night exercise. - Delayed sleep onset - Shorter total sleep duration - Lower sleep quality - Higher resting heart rate (RHR) - Decreased heart rate variability (HRV) More details Sleep onset Even workouts ending X hours before bed delayed sleep if they were high or maximal strain. Maximal intensity at X hours before bed = 36-minute delay in falling asleep vs. light exercise. Sleep duration Exercise within XX hours of bedtime associated with shorter"  
[X Link](https://x.com/bryan_johnson/status/1914818988271657452) [@bryan_johnson](/creator/x/bryan_johnson) 2025-04-22T23:09Z 662.6K followers, 305.4K engagements


"Most men think the average erect penis is XXX inches. Its not. That data is self-reported. The actual global average is XXXX inches (13.61 cm) according to a 2020 meta-analysis of XX studies. Heres how to collect your own penis size data accurately"  
[X Link](https://x.com/bryan_johnson/status/1950974686260863380) [@bryan_johnson](/creator/x/bryan_johnson) 2025-07-31T17:39Z 662.6K followers, 212.9K engagements


"If you have anxiety try scheduling your worry time earlier in the day so it doesnt interfere with your sleep"  
[X Link](https://x.com/bryan_johnson/status/1960425544023236701) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-26T19:34Z 662.6K followers, 1.8M engagements


"Nietzsche agrees with me on sleep ht @Grimezsz"  
[X Link](https://x.com/bryan_johnson/status/1962245471176687744) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-31T20:05Z 662.6K followers, 177.4K engagements


"Before Don't Die I built in payments founding Braintree Venmo. Excited for the next frontier with Stable and @paoloardoino"  
[X Link](https://x.com/bryan_johnson/status/1962262170684842005) [@bryan_johnson](/creator/x/bryan_johnson) 2025-08-31T21:12Z 662.6K followers, 401.3K engagements


"People once trembled at lunar and solar eclipses. Kings staged sacrifices crowds beat drums all to fight shadows they couldnt understand. Death is our modern eclipse. We fear it surrender to it ritualize it. Soon as our knowledge advances fearing death will seem as absurd as fearing the Moons shadow"  
[X Link](https://x.com/bryan_johnson/status/1964765674569613534) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-07T19:00Z 662.6K followers, 134.1K engagements


"Have we gone too far Sparkling protein with a splash of sucralose for microbiome damage and insulin resistance"  
[X Link](https://x.com/bryan_johnson/status/1971379477214265652) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-26T01:01Z 662.6K followers, 258.5K engagements


"Something catastrophic has happened. Yesterday I traveled to the mountains stayed up past my bedtime and didnt have a wind down routine. My sleep deprived state has slowed my reaction times impaired judgment and put me at risk of making bad decisions. What do I do"  
[X Link](https://x.com/bryan_johnson/status/1971576711126081742) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-26T14:04Z 662.6K followers, 288.1K engagements


"my near death experience"  
[X Link](https://x.com/bryan_johnson/status/1971665810432446767) [@bryan_johnson](/creator/x/bryan_johnson) 2025-09-26T19:58Z 662.6K followers, 204.8K engagements


"Is choking during sex good or bad"  
[X Link](https://x.com/bryan_johnson/status/1974174306948280629) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-03T18:06Z 662.6K followers, 232.1K engagements


"If you're scrolling with one hand and snacking with the other you're a human GPU"  
[X Link](https://x.com/bryan_johnson/status/1975018746575278431) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-06T02:02Z 662.6K followers, 104.2K engagements


"Its Monday. On average people feel a bit lower mood Monday blues. Some even show higher cumulative stress hormone levels tied to how anxious they feel that day. How are you doing"  
[X Link](https://x.com/bryan_johnson/status/1975178438052126859) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-06T12:36Z 662.6K followers, 84.3K engagements


"GLP-1s raise your resting rate which can degrade sleep quality and lower HRV. I microdosed Tirzepatide (0.5mg/day) and it increased my RHR by X bpm and lowered my HRV by X. + Liraglutide: +610 bpm + Semaglutide: +24 bpm + Tirzepatide: +1.53.5 bpm Good to know in case youre wondering why your heart rate is higher or your sleep a bit worse"  
[X Link](https://x.com/bryan_johnson/status/1975322172345421951) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-06T22:08Z 662.6K followers, 687.1K engagements


"Most people tell me the future has to be a certain way for them to want it. That sounds like hell Im eager to suspend all my ideas of existence. Open to all possibilities. After all humans are notoriously bad at knowing what they will or wont want"  
[X Link](https://x.com/bryan_johnson/status/1975570767111962950) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-07T14:35Z 662.6K followers, 56.1K engagements


"Its been really helpful to try and think deeply about fast food and what it reveals about us as a species. I think McDonalds and others are fundamentally a philosophy of decay and we like to dismiss it as inconsequential to avoid reconciling with this disturbing truth"  
[X Link](https://x.com/bryan_johnson/status/1975672378228416791) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-07T21:19Z 662.6K followers, 98.6K engagements


"Works every time"  
[X Link](https://x.com/bryan_johnson/status/1975711277432643614) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-07T23:54Z 662.6K followers, 105.7K engagements


"Eating spicy chili peppers might reduce your risk of death. A study of 500000+ people found that regular chili eaters: + XX% lower rate of all-cause death + XX% lower rate of cardiovascular death + XX% lower rate of cancer death Compared to those who rarely ate chili. Hot ones im ready for you"  
[X Link](https://x.com/bryan_johnson/status/1976359318267232556) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-09T18:49Z 662.6K followers, 312.3K engagements


"Oxytocin: i love you Dopamine: pls like me"  
[X Link](https://x.com/bryan_johnson/status/1976416885659873454) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-09T22:38Z 662.6K followers, 141.9K engagements


"Dont mouthwash after a workout. Rinsing with antiseptic mouthwash after exercise can blunt the benefits of a workout. Antibacterial mouthwash cut over XX% of exercises blood-pressure-lowering effect after X hour. And fully canceled it X hours post-exercise"  
[X Link](https://x.com/bryan_johnson/status/1976734750036631700) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T19:41Z 662.6K followers, 152.1K engagements


"Ppl spend hundreds of thousands on gene therapies to boost VEGF by 2-3x. My morning routine boosted my VEGF by 22x now top X% of healthy individuals. VEGF is vital for blood vessel maintenance remodeling and growth (angiogenesis)"  
[X Link](https://x.com/bryan_johnson/status/1976747892372390136) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-10T20:33Z 662.6K followers, 90.1K engagements


"will explain more soon"  
[X Link](https://x.com/bryan_johnson/status/1977040420120281109) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-11T15:55Z 662.6K followers, 50.7K engagements


"For those of you who want to rebel against societal addictions and reclaim yourself join me this week: X. final food X hr before bed X. screens off XX min before sleep X. read book in hand XX min before bed The self respect will feel amazing. Commit with a like tell me how you did when I post again about this on Saturday. Eating earlier will lower your resting heart rate which will boost your sleep. High quality sleep boosts your will power. Will power boosts good decision making everywhere. Late night eating increases blood glucose insulin and core body temp suppressing melatonin release."  
[X Link](https://x.com/bryan_johnson/status/1977793059816652840) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-13T17:46Z 662.6K followers, 212.7K engagements


"dropping this week"  
[X Link](https://x.com/bryan_johnson/status/1977810430832812230) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-13T18:55Z 662.6K followers, 110.9K engagements


"I'm thinking of retiring from Don't Die and building Die. Wondering who'd be interested in that"  
[X Link](https://x.com/bryan_johnson/status/1977881061330755790) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-13T23:36Z 662.6K followers, 277.6K engagements


"Young people feel guilty about getting high quality sleep. This is the moral inversion of rest. Sleep is sin. Fatigue as virtue and rejuvenation as vice"  
[X Link](https://x.com/bryan_johnson/status/1978501889240027312) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-15T16:43Z 662.6K followers, 117.2K engagements


"I reduced a cognitive decline marker by XX% using HBOT and sauna. Serum pTAU217 is a marker for Alzheimer's disease. A year ago my pTAU217 level was in the upper normal range at XXXX pg/mL (with XXXX pg/mL being a commonly used cut-off value). This was mildly concerning even in the absence of any signs of plaque in my routine brain MRI. Following XX HBOT sessions my pTAU-levels dropped by XX% to the mid-normal range at XXXX pg/mL. This improvement lasted over X months with continued HBOT and the addition of sauna to my morning routine. A few months ago I observed a further small improvement a"  
[X Link](https://x.com/bryan_johnson/status/1978926605360926885) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-16T20:50Z 662.6K followers, 118.4K engagements


"what i'm eating this week"  
[X Link](https://x.com/bryan_johnson/status/1978984465390043237) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-17T00:40Z 662.6K followers, 1.1M engagements


"Self-view on zoom makes you feel bad distracted and fatigued.but only if you're naturally self-conscious. Try turning it off. If you're not self-conscious self-view can be reassuring and even positive"  
[X Link](https://x.com/bryan_johnson/status/1979663650723086484) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-18T21:39Z 662.6K followers, 65.7K engagements


"Veronica cool youre trying things to improve your health. This CO inhalation therapy carries real risk of unintended harm. CO is a waste product of mitochondrial respiration. The body works constantly to eliminate it not accumulate it. Theres no evidence that inhaling CO boosts metabolism or energy. In fact elevated CO (hypercapnia) is linked to mitochondrial dysfunction reduced energy capacity inflammation and immune suppression. Whats often overlooked is that CO is the bodys main signal for breathing regulation. Specialized sensors in the brainstem and carotid arteries continuously monitor"  
[X Link](https://x.com/bryan_johnson/status/1980307024283099320) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-20T16:16Z 662.6K followers, 170.5K engagements


"@Tallowtwins I could be mistaken but it looks like driver took pic while traveling XX mph using one hand to hold the cheese and the other to take the pic her left knee steering. Creating a 12x increased crash risk. The 4-6 sec required to take pic means they traveled XXX ft blind"  
[X Link](https://x.com/bryan_johnson/status/1980353180149117339) [@bryan_johnson](/creator/x/bryan_johnson) 2025-10-20T19:19Z 662.6K followers, 59.4K engagements