[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] [@MichaelOkun](/creator/twitter/MichaelOkun) "Nicotine in Parkinsons is it a friend or foe There is a long-standing puzzle in Parkinsons research that smokers have a lower risk of developing Parkinsons disease. A new deep-dive review by Kumari Cooke and Olsen in the Journal of Parkinsons Disease explores the many mechanisms by which nicotine (and not smoking) might protect the brain. Spoiler alert: dont light up or run out to get patches. Key Points: - Nicotine protects dopamine neurons in lab and animal models by reducing oxidative stress modulating mitochondrial function and by dampening inflammation. - Nicotinic receptors and"  [@MichaelOkun](/creator/x/MichaelOkun) on [X](/post/tweet/1944713204598284446) 2025-07-14 10:58:53 UTC 37.9K followers, 4691 engagements "RIP Ozzy Osbourne (1948 2025). As a global rock icon Ozzy inspired millions with his music but even more profoundly he moved the Parkinsons community by bravely sharing his diagnosis and becoming a pioneer in the conversation around advanced therapies including stem cell treatments. His transparency gave hope to countless individuals and families navigating this challenging journey. I am grateful for his courage candor and commitment to progress in Parkinsons research. We honored his story and explained the type of Parkinson's he had (PARKIN gene) in the publication The Conversation which can"  [@MichaelOkun](/creator/x/MichaelOkun) on [X](/post/tweet/1947747755864297658) 2025-07-22 19:57:07 UTC 37.9K followers, 14.4K engagements "Could your diabetes medication protect your brain from Parkinson's Alzheimer's and dementia A just-published study in JAMA Network Open by Lin and colleagues adds serious weight to the idea that drugs like semaglutide (Ozempic Wegovy) and tirzepatide (Mounjaro Zepbound) may do more than lower blood sugar and trim your waistline. Could they shield your brain and blood vessels from long-term damage Key Points: - The authors showed that there was a lower dementia risk w/ GLP-1 drugs. - Semaglutide and tirzepatide were associated w/ a XX% reduced risk of dementia in type X diabetes and in those"  [@MichaelOkun](/creator/x/MichaelOkun) on [X](/post/tweet/1946546899688825202) 2025-07-19 12:25:20 UTC 37.9K followers, 6125 engagements "Can specialized physical therapy help you to live longer with Parkinsons What if physical therapy did more than improve balance and reduce falls A new Dutch study by Ypinga Bloem and colleagues just dropped and the results are fascinating. Specialized physical therapy like that provided through the ParkinsonNet model was linked to a modest but real reduction in mortality for people w/ Parkinsons. Key Points: - Specialized physical therapy for Parkinsons was linked to an XX% lower risk of death compared to usual care. - The benefit was specific to therapy focused on Parkinsons related"  [@MichaelOkun](/creator/x/MichaelOkun) on [X](/post/tweet/1948377120209612968) 2025-07-24 13:37:59 UTC 37.9K followers, 2461 engagements "What about using nanoparticles to treat Parkinson's Could we guide Parkinsons repair one axon at a time Could magnetic nanoparticles help repair the Parkinsons brain A new study in Advanced Science delivers one of the most creative strategies yet. It is called nano-pulling. By using gentle mechanical forces scientists directed stem cell derived dopamine neurons to grow in a specific direction. Think of the technique as a potential 'GPS system for brain wiring.' Key Points: - Nano-pulling uses magnetic nanoparticles and external magnetic fields to guide axonal growth of transplanted"  [@MichaelOkun](/creator/x/MichaelOkun) on [X](/post/tweet/1948729965186306087) 2025-07-25 13:00:04 UTC 37.9K followers, XXX engagements "How does the brain stop a thought in its tracks Ever get stuck on a thought you just can't shake Whether it's an unwanted memory an intrusive worry or a pathological mental loop a new paper in Nature Reviews Neuroscience by Michael Anderson and colleagues shines light on how it all works. Key Points: - 'Thought stopping' engages a domain general brain system. - The system is centered in the right dorsolateral and ventrolateral prefrontal cortex. - There is overlap w/ the circuitry for action stopping. - There are unique connections to memory. - There is a fronto-temporal inhibitory control"  [@MichaelOkun](/creator/x/MichaelOkun) on [X](/post/tweet/1939654610173460493) 2025-06-30 11:57:50 UTC 37.9K followers, 84.5K engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@MichaelOkun
"Nicotine in Parkinsons is it a friend or foe There is a long-standing puzzle in Parkinsons research that smokers have a lower risk of developing Parkinsons disease. A new deep-dive review by Kumari Cooke and Olsen in the Journal of Parkinsons Disease explores the many mechanisms by which nicotine (and not smoking) might protect the brain. Spoiler alert: dont light up or run out to get patches. Key Points: - Nicotine protects dopamine neurons in lab and animal models by reducing oxidative stress modulating mitochondrial function and by dampening inflammation. - Nicotinic receptors and"
@MichaelOkun on X 2025-07-14 10:58:53 UTC 37.9K followers, 4691 engagements
"RIP Ozzy Osbourne (1948 2025). As a global rock icon Ozzy inspired millions with his music but even more profoundly he moved the Parkinsons community by bravely sharing his diagnosis and becoming a pioneer in the conversation around advanced therapies including stem cell treatments. His transparency gave hope to countless individuals and families navigating this challenging journey. I am grateful for his courage candor and commitment to progress in Parkinsons research. We honored his story and explained the type of Parkinson's he had (PARKIN gene) in the publication The Conversation which can" @MichaelOkun on X 2025-07-22 19:57:07 UTC 37.9K followers, 14.4K engagements
"Could your diabetes medication protect your brain from Parkinson's Alzheimer's and dementia A just-published study in JAMA Network Open by Lin and colleagues adds serious weight to the idea that drugs like semaglutide (Ozempic Wegovy) and tirzepatide (Mounjaro Zepbound) may do more than lower blood sugar and trim your waistline. Could they shield your brain and blood vessels from long-term damage Key Points: - The authors showed that there was a lower dementia risk w/ GLP-1 drugs. - Semaglutide and tirzepatide were associated w/ a XX% reduced risk of dementia in type X diabetes and in those" @MichaelOkun on X 2025-07-19 12:25:20 UTC 37.9K followers, 6125 engagements
"Can specialized physical therapy help you to live longer with Parkinsons What if physical therapy did more than improve balance and reduce falls A new Dutch study by Ypinga Bloem and colleagues just dropped and the results are fascinating. Specialized physical therapy like that provided through the ParkinsonNet model was linked to a modest but real reduction in mortality for people w/ Parkinsons. Key Points: - Specialized physical therapy for Parkinsons was linked to an XX% lower risk of death compared to usual care. - The benefit was specific to therapy focused on Parkinsons related" @MichaelOkun on X 2025-07-24 13:37:59 UTC 37.9K followers, 2461 engagements
"What about using nanoparticles to treat Parkinson's Could we guide Parkinsons repair one axon at a time Could magnetic nanoparticles help repair the Parkinsons brain A new study in Advanced Science delivers one of the most creative strategies yet. It is called nano-pulling. By using gentle mechanical forces scientists directed stem cell derived dopamine neurons to grow in a specific direction. Think of the technique as a potential 'GPS system for brain wiring.' Key Points: - Nano-pulling uses magnetic nanoparticles and external magnetic fields to guide axonal growth of transplanted" @MichaelOkun on X 2025-07-25 13:00:04 UTC 37.9K followers, XXX engagements
"How does the brain stop a thought in its tracks Ever get stuck on a thought you just can't shake Whether it's an unwanted memory an intrusive worry or a pathological mental loop a new paper in Nature Reviews Neuroscience by Michael Anderson and colleagues shines light on how it all works. Key Points: - 'Thought stopping' engages a domain general brain system. - The system is centered in the right dorsolateral and ventrolateral prefrontal cortex. - There is overlap w/ the circuitry for action stopping. - There are unique connections to memory. - There is a fronto-temporal inhibitory control" @MichaelOkun on X 2025-06-30 11:57:50 UTC 37.9K followers, 84.5K engagements