Dark | Light
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

# ![@johnkmason Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::2421442308.png) @johnkmason John Mason

John Mason posts on X about $qure, for all, $sprb, maga the most. They currently have XXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours.

### Engagements: XXXXX [#](/creator/twitter::2421442308/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::2421442308/c:line/m:interactions.svg)

- X Week XXXXXX +641%
- X Month XXXXXX +147%
- X Months XXXXXXX +119%
- X Year XXXXXXX +98%

### Mentions: X [#](/creator/twitter::2421442308/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::2421442308/c:line/m:posts_active.svg)

- X Week X -XX%
- X Month XX +14%
- X Months XXX +88%
- X Year XXX +59%

### Followers: XXX [#](/creator/twitter::2421442308/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::2421442308/c:line/m:followers.svg)

- X Week XXX +4.70%
- X Month XXX +14%
- X Months XXX +47%
- X Year XXX +72%

### CreatorRank: XXXXXXXXX [#](/creator/twitter::2421442308/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::2421442308/c:line/m:influencer_rank.svg)

### Social Influence

**Social category influence**
[technology brands](/list/technology-brands)  XXXX%

**Social topic influence**
[$qure](/topic/$qure) #4, [for all](/topic/for-all) 8.33%, [$sprb](/topic/$sprb) 8.33%, [maga](/topic/maga) 4.17%, [staff](/topic/staff) 4.17%, [longterm](/topic/longterm) 4.17%, [just a](/topic/just-a) 4.17%, [sap](/topic/sap) 4.17%, [$qures](/topic/$qures) 4.17%, [the latest](/topic/the-latest) XXXX%

**Top accounts mentioned or mentioned by**
[@sowingalphaseed](/creator/undefined) [@ab1001disciple](/creator/undefined) [@alvaro6v](/creator/undefined) [@brainymarsupial](/creator/undefined) [@yoyoyogim23490](/creator/undefined) [@ab1001_disciple](/creator/undefined) [@drmakaryfda](/creator/undefined) [@lizzylaw](/creator/undefined) [@kingdomcapadv](/creator/undefined) [@natstewart5](/creator/undefined) [@mrneutralman](/creator/undefined) [@dalfornocapital](/creator/undefined) [@hparkerevans](/creator/undefined) [@mayhem4markets](/creator/undefined) [@petersarsby](/creator/undefined) [@docrodwong](/creator/undefined) [@finfreedom414](/creator/undefined) [@mstyhodler](/creator/undefined) [@shmuellon](/creator/undefined) [@finphysnerd](/creator/undefined)

**Top assets mentioned**
[uniQure N.V. (QURE)](/topic/$qure)
### Top Social Posts
Top posts by engagements in the last XX hours

"Last thought re: $QURE. Just thinking through the patient cohorts again I strongly believe that the modal outcome for AMT-130 will be FDA requiring the last X patients in the high-dose group to report XX mo (and first XX report XX mo) before BLA submission"  
[X Link](https://x.com/johnkmason/status/1996788046164119646)  2025-12-05T03:45Z XXX followers, 7516 engagements


"This is truly fucking insane. @DrMakaryFDA is having AIDES vote on DRUG APPROVALS Absolutely disgusting. Any MAGA Trumpers wanna look at this and explain how this isn't absurd $QURE"  
[X Link](https://x.com/johnkmason/status/1991946395415126332)  2025-11-21T19:06Z XXX followers, 19K engagements


"Re: $QURE. Would love to hear some pushback from folks on some recent thoughts. FDA turmoil aside I'm toying with the idea that $QURE is actually a great long-term hold in IRAs (to avoid PFIC). 🧵"  
[X Link](https://x.com/johnkmason/status/1996414351285366903)  2025-12-04T03:00Z XXX followers, 3196 engagements


"Talking to my scientist-in-training wife re: $QURE I realized there's a third possibility. 🧵"  
[X Link](https://x.com/johnkmason/status/1996445148377665602)  2025-12-04T05:03Z XXX followers, 5028 engagements


"Based on all of $QURE's comms isn't this the most plausible explanation Not accepting the current data based on XX patients at 36-months and holding out for all XX high-dose at 36-months (plus the initial XX at 48-months) seems FAR more likely than ENTIRELY new RCT"  
[X Link](https://x.com/johnkmason/status/1996788047996707014)  2025-12-05T03:45Z XXX followers, XXX engagements


"This is conditional on: X. You believe AMT-130 works. I do. X. You believe Vinay Prasad will not require a Ph X RCT. The subsequent cash burn and dilution kills this case. If the above two things are true this will still be a 3-4x in X years"  
[X Link](https://x.com/johnkmason/status/1996414353177026560)  2025-12-04T03:00Z XXX followers, 7844 engagements


"@basadomente @Jonny_fun_guy So the sham surgery patients should have been asked to just accept XX% of the permanent degeneration required to die of Huntingtons Come on man. Do you really think that Even when they have dose dependent response as a pseudo control"  
[X Link](https://x.com/johnkmason/status/1996780067381235880)  2025-12-05T03:14Z XXX followers, XXX engagements


"This means we have to wait until Thanksgiving next year at the latest to wait for the 36-mo to be reached (and reported out) for all X of those remaining patients. I'll be placing my bets accordingly"  
[X Link](https://x.com/johnkmason/status/1996788806104817987)  2025-12-05T03:48Z XXX followers, XXX engagements


"I just keep reading today's presser "the FDA conveyed that data submitted from the Phase I/II studies of AMT-130 are CURRENTLY unlikely to provide the primary evidence to support a BLA submission.""  
[X Link](https://x.com/johnkmason/status/1996790586225930342)  2025-12-05T03:55Z XXX followers, XXX engagements


"The "currently" keeps bouncing around in my head. Currently- based on XX high/12 low patients at XX mo vs XX at 36mo and XX high/12 low at 48mo. Plus I just don't believe the Vinay Prasad who gave that NORD preso would require $QURE to do a brand-new RCT + X more years"  
[X Link](https://x.com/johnkmason/status/1996791454371594630)  2025-12-05T03:59Z XXX followers, XXX engagements


"Loaded up on $SPRB here below $XX. If you have been paying attention you know that this drop is due to the Oct XX S-3 filing. The corresponding EFFECT filing hit last week on Nov 26"  
[X Link](https://x.com/johnkmason/status/1995591273093497205)  2025-12-01T20:30Z XXX followers, 1571 engagements


"Wrote a quick writeup of $SPRB. Would love feedback from folks @Biohazard3737 @BrainyMarsupial @MartinShkreli @peter_mantas @AB1001_disciple @A_May_MD @seedy19tron @blankspacenom @MattyKirsh"  
[X Link](https://x.com/johnkmason/status/1997700089863967168)  2025-12-07T16:09Z XXX followers, 4690 engagements

[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

@johnkmason Avatar @johnkmason John Mason

John Mason posts on X about $qure, for all, $sprb, maga the most. They currently have XXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours.

Engagements: XXXXX #

Engagements Line Chart

  • X Week XXXXXX +641%
  • X Month XXXXXX +147%
  • X Months XXXXXXX +119%
  • X Year XXXXXXX +98%

Mentions: X #

Mentions Line Chart

  • X Week X -XX%
  • X Month XX +14%
  • X Months XXX +88%
  • X Year XXX +59%

Followers: XXX #

Followers Line Chart

  • X Week XXX +4.70%
  • X Month XXX +14%
  • X Months XXX +47%
  • X Year XXX +72%

CreatorRank: XXXXXXXXX #

CreatorRank Line Chart

Social Influence

Social category influence technology brands XXXX%

Social topic influence $qure #4, for all 8.33%, $sprb 8.33%, maga 4.17%, staff 4.17%, longterm 4.17%, just a 4.17%, sap 4.17%, $qures 4.17%, the latest XXXX%

Top accounts mentioned or mentioned by @sowingalphaseed @ab1001disciple @alvaro6v @brainymarsupial @yoyoyogim23490 @ab1001_disciple @drmakaryfda @lizzylaw @kingdomcapadv @natstewart5 @mrneutralman @dalfornocapital @hparkerevans @mayhem4markets @petersarsby @docrodwong @finfreedom414 @mstyhodler @shmuellon @finphysnerd

Top assets mentioned uniQure N.V. (QURE)

Top Social Posts

Top posts by engagements in the last XX hours

"Last thought re: $QURE. Just thinking through the patient cohorts again I strongly believe that the modal outcome for AMT-130 will be FDA requiring the last X patients in the high-dose group to report XX mo (and first XX report XX mo) before BLA submission"
X Link 2025-12-05T03:45Z XXX followers, 7516 engagements

"This is truly fucking insane. @DrMakaryFDA is having AIDES vote on DRUG APPROVALS Absolutely disgusting. Any MAGA Trumpers wanna look at this and explain how this isn't absurd $QURE"
X Link 2025-11-21T19:06Z XXX followers, 19K engagements

"Re: $QURE. Would love to hear some pushback from folks on some recent thoughts. FDA turmoil aside I'm toying with the idea that $QURE is actually a great long-term hold in IRAs (to avoid PFIC). 🧵"
X Link 2025-12-04T03:00Z XXX followers, 3196 engagements

"Talking to my scientist-in-training wife re: $QURE I realized there's a third possibility. 🧵"
X Link 2025-12-04T05:03Z XXX followers, 5028 engagements

"Based on all of $QURE's comms isn't this the most plausible explanation Not accepting the current data based on XX patients at 36-months and holding out for all XX high-dose at 36-months (plus the initial XX at 48-months) seems FAR more likely than ENTIRELY new RCT"
X Link 2025-12-05T03:45Z XXX followers, XXX engagements

"This is conditional on: X. You believe AMT-130 works. I do. X. You believe Vinay Prasad will not require a Ph X RCT. The subsequent cash burn and dilution kills this case. If the above two things are true this will still be a 3-4x in X years"
X Link 2025-12-04T03:00Z XXX followers, 7844 engagements

"@basadomente @Jonny_fun_guy So the sham surgery patients should have been asked to just accept XX% of the permanent degeneration required to die of Huntingtons Come on man. Do you really think that Even when they have dose dependent response as a pseudo control"
X Link 2025-12-05T03:14Z XXX followers, XXX engagements

"This means we have to wait until Thanksgiving next year at the latest to wait for the 36-mo to be reached (and reported out) for all X of those remaining patients. I'll be placing my bets accordingly"
X Link 2025-12-05T03:48Z XXX followers, XXX engagements

"I just keep reading today's presser "the FDA conveyed that data submitted from the Phase I/II studies of AMT-130 are CURRENTLY unlikely to provide the primary evidence to support a BLA submission.""
X Link 2025-12-05T03:55Z XXX followers, XXX engagements

"The "currently" keeps bouncing around in my head. Currently- based on XX high/12 low patients at XX mo vs XX at 36mo and XX high/12 low at 48mo. Plus I just don't believe the Vinay Prasad who gave that NORD preso would require $QURE to do a brand-new RCT + X more years"
X Link 2025-12-05T03:59Z XXX followers, XXX engagements

"Loaded up on $SPRB here below $XX. If you have been paying attention you know that this drop is due to the Oct XX S-3 filing. The corresponding EFFECT filing hit last week on Nov 26"
X Link 2025-12-01T20:30Z XXX followers, 1571 engagements

"Wrote a quick writeup of $SPRB. Would love feedback from folks @Biohazard3737 @BrainyMarsupial @MartinShkreli @peter_mantas @AB1001_disciple @A_May_MD @seedy19tron @blankspacenom @MattyKirsh"
X Link 2025-12-07T16:09Z XXX followers, 4690 engagements

@johnkmason
/creator/twitter::johnkmason