# Spruce Biosciences, Inc. (SPRB)

Spruce Biosciences (SPRB) faces regulatory uncertainty following a CRL for Disc Medicine (IRON), impacting SPRB's price. Investors are closely watching for regulatory tailwinds and considering buying dips amidst speculative interest.

### About Spruce Biosciences, Inc.
Spruce Biosciences, Inc. is a biotechnology company focused on developing therapies for rare diseases.  
Spruce Biosciences, Inc. uses the ticker $SPRB for trading. Listed in the [Stocks](/list/stocks) category.

### Insights
- Spruce Biosciences, Inc. (SPRB) mentions hit [---] which is 192% higher than it's daily average.
- Spruce Biosciences, Inc. (SPRB) creators hit [---] which is 138% higher than it's daily average.
- Spruce Biosciences, Inc. (SPRB) social dominance hit [------] which is 128% higher than it's daily average.
- Spruce Biosciences, Inc. (SPRB) trading volume is up 723.41% from the previous month.
- Spruce Biosciences, Inc. (SPRB) social dominance is up 2220% from the previous [--] months.
- Spruce Biosciences, Inc. (SPRB) Galaxy Score™ is up 275% from the previous [--] months.
- Spruce Biosciences, Inc. (SPRB) engagements is up 79.61% from the previous week.
- Spruce Biosciences, Inc. (SPRB) mentions is up 12.45% from the previous week.
- Spruce Biosciences, Inc. (SPRB) posts created is up 130.77% from the previous week.
- Spruce Biosciences, Inc. Price hit a 52-Week high of $86.90 for the hour
- Spruce Biosciences, Inc. Price hit an all time of $86.90 for the hour

### Price: $66.30
![Price Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:close/iv:1d.svg)  
[Price 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/close.tsv)  
SPRB's price action is likely influenced by regulatory uncertainty and positive sentiment around technological advancements, with investors showing interest in buying dips.  

24-Hour: -18.84%
7-Day: -8.19%
30-Day: -9.85%

1-Year High: $182.60 on 2025-10-07  
1-Year Low: $0.06 on 2025-06-09  
  
  
### AltRank: [---]
![AltRank Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:alt_rank/iv:1d.svg)  
[AltRank 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/alt_rank.tsv)  
Spruce Biosciences, Inc. (SPRB) is currently AltRank #159 based on combined combined social and market metrics
Daily Average: [---]  
[--] Week: [---] +107  
1-Year High: [-----] on 2026-02-05  
1-Year Low: [--] on 2026-01-24  
  
  
### Galaxy Score: [-----]
![Galaxy Score Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:galaxy_score/iv:1d.svg)  
[Galaxy Score 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/galaxy_score.tsv)  
Current Value: [-----]  
Daily Average: [--]  
[--] Week: [--] +8  
[--] Month: [--] +21  
[--] Months: [--] +40  
[--] Year: [--] +23  
1-Year High: [--] on 2026-02-02  
1-Year Low: [--] on 2025-06-01  
  
  
### Engagements: [------] (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/interactions.tsv)  
Current Value: [------]  
Daily Average: [------]  
[--] Week: [------] +80%  
[--] Month: [-------] -0.29%  
[--] Months: [---------] +2,242%  
[--] Year: [---------] +1,098%  
1-Year High: [---------] on 2025-10-06  
1-Year Low: [--] on 2025-08-11  

Engagements by network (24h):
YouTube: [--]
Reddit: [--]
News: [--]
X: [------]
TikTok: [--]

  
  
### Mentions: [---] (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/posts_active.tsv)  
Current Value: [---]  
Daily Average: [--]  
[--] Week: [---] +12%  
1-Year High: [-----] on 2025-10-07  
1-Year Low: [--] on 2025-09-11  

Mentions by network (24h):
YouTube: [--]
Reddit: [--]
News: [--]
X: [---]
TikTok: [--]

  
  
### Creators: [---] (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/contributors_active.tsv)  
[---] unique social accounts have posts mentioning Spruce Biosciences, Inc. (SPRB) in the last [--] hours which is up 163% from [--] in the previous [--] hours
Daily Average: [--]  
[--] Week: [---] +8.20%  
1-Year High: [-----] on 2025-10-07  
1-Year Low: [--] on 2025-09-11  

The most influential creators that mention Spruce Biosciences, Inc. in the last [--] hours

| Creator                                              | Rank | Followers | Posts | Engagements |
| -------                                              | ---- | --------- | ----- | ----------- |
| [@surferbackpack](/creator/twitter/surferbackpack)   | [--]    | [---]       | [--]     | [-----]       |
| [@EmuConspiracy](/creator/twitter/EmuConspiracy)     | [--]    | [---]       | [--]     | [-----]       |
| [@BayStreetBull](/creator/twitter/BayStreetBull)     | [--]    | [---]       | [--]     | [-----]       |
| [@jacobg0121](/creator/twitter/jacobg0121)           | [--]    | [---]       | [--]     | [---]         |
| [@Relic57647069](/creator/twitter/Relic57647069)     | [--]    | [--]        | [--]     | [---]         |
| [@Trade_market100](/creator/twitter/Trade_market100) | [--]    | [--]        | [--]     | [---]         |
| [@MiriamF24887120](/creator/twitter/MiriamF24887120) | [--]    | [--]        | [--]     | [---]         |
| [@Lola59652](/creator/twitter/Lola59652)             | [--]    | [--]         | [--]     | [---]         |
| [@Trade_market30](/creator/twitter/Trade_market30)   | [--]    | [--]        | [--]     | [---]         |
| [@Stock_Analysis6](/creator/twitter/Stock_Analysis6) | [--]   | [---]       | [--]     | [---]         |

[View More](/list/creators/$sprb/100)
  
  
### Sentiment: 62%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/sentiment.tsv)  
Current Value: 62%  
Daily Average: 77%  
[--] Week: 60% -15%  
[--] Month: 54% -6%  
[--] Months: 54% +4%  
[--] Year: 54% -16%  
1-Year High: 100% on 2025-02-17  
1-Year Low: 18% on 2026-01-16  

Most Supportive Themes:
- Community Building: (40%) Discussions focus on strengthening the community through events and collaborations.
- Technological Advancements: (30%) Updates and insights into the ongoing development and improvements of the currency's technology.
- Adoption and Use Cases: (20%) Sharing news and examples of how the currency is being adopted and used in real-world applications.
  
Most Critical Themes:
- Regulatory Uncertainty: (60%) Concerns and discussions surrounding potential government regulations and their impact on the currency.
- Market Volatility: (40%) Analysis and reactions to the currency's price fluctuations and overall market sentiment.
  
  
  
### Social Dominance: 0.016%
![Social Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:social_dominance/iv:1d.svg)  
[Social Dominance 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/social_dominance.tsv)  
Current Value: 0.016%  
Daily Average: 0.01%  
[--] Week: 0.015% +0.00985%  
[--] Month: 0.023% +0.02%  
[--] Months: 0.023% +0.022%  
[--] Year: 0.023% +0.017%  
1-Year High: 0.269% on 2025-10-07  
1-Year Low: 0.0001% on 2025-09-11  
  
  
### Market Dominance: 0.00010056002162869987%
![Market Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:market_dominance/iv:1d.svg)  
[Market Dominance 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/market_dominance.tsv)  
Current Value: 0.00010056002162869987%  
Daily Average: 0%  
1-Year High: 0.00388% on 2026-02-12  
1-Year Low: 0.0001% on 2026-02-13  
  
  
### Market Cap: $88,797,895
![Market Cap Line Chart](https://lunarcrush.com/gi/w:600/t:$sprb/c:line/m:market_cap/iv:1d.svg)  
[Market Cap 24-Hour Time-Series Raw Data](/topic/$sprb/time-series/market_cap.tsv)  
Current Value: $88,797,895  
Daily Average: $83,413,071  
[--] Week: $72,068,012 -9.50%  
[--] Month: $70,954,827 -11%  
1-Year High: $91,238,339 on 2026-01-22  
1-Year Low: $70,954,827 on 2026-02-13  

### Top Spruce Biosciences, Inc. Social Posts
Top posts by engagements in the last [--] hours

*Showing a maximum of [--] top social posts without a LunarCrush subscription.*

"$sprb FDA complete response letter to peer Disc Medicine (IRON) triggered SPRB's 20% plunge"  
[X Link](https://x.com/bkfViking123/status/2022553388542545953) [@bkfViking123](/creator/x/bkfViking123) 2026-02-14T06:07Z 16.7K followers, [---] engagements


"$SPRB a top investment of [----] at these prices https://youtu.be/VxFDeN3ughw https://youtu.be/VxFDeN3ughw"  
[X Link](https://x.com/Deepvalue69420/status/2022528164241772833) [@Deepvalue69420](/creator/x/Deepvalue69420) 2026-02-14T04:27Z [----] followers, [---] engagements


"i actually don't know much about the $IRON biomarker. or the $SPRB one. but if you guys want a good primer you ought to dig into MRD for myeloma. this is ostensibly a great biomarker for disease that gets propped up by almost every KOL pretty regularly and which lead to the ODAC approval in [----]. this was reaffirmed a couple weeks ago by the current FDA as a surrogate endpoint in AA for NDMM *with* some guardrails the idea of MRD in myeloma is straightforward: low myeloma cells (10-5 10-6) means good response. since myeloma cells are the disease this makes sense. so this is a sound statement"  
[X Link](https://x.com/anthonystaj/status/2022525183727202673) [@anthonystaj](/creator/x/anthonystaj) 2026-02-14T04:15Z [----] followers, [----] engagements


"$SPRB adding on Monday. $IRON : PPIX had no validation as an endpoint. Weak correlation with clinical outcomes. Focused on reduction of PPIX. $RGNX : [--] year trial data Used HS-D2S6 (noisy). Focused on reduction. $SPRB : [--] year data HS-NRE Focused on Normalization"  
[X Link](https://x.com/surferbackpack/status/2022513647109705771) [@surferbackpack](/creator/x/surferbackpack) 2026-02-14T03:30Z [---] followers, [---] engagements

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