# uniQure N.V. (QURE)

uniQure announces updated preliminary AMT-191 Phase I/IIa data showing sustained increases in enzyme activity. Institutional holdings data shows State Street Corp increasing its stake significantly.

### About uniQure N.V.
uniQure N.V. is a biotechnology company focused on gene therapy for severe diseases.  
uniQure N.V. uses the ticker $QURE for trading. Listed in the [Stocks](/list/stocks) category within the [Healthcare](/list/stocks/healthcare) sectors.

### Insights
- uniQure N.V. (QURE) market dominance near a 52-week low at [-------].
- uniQure N.V. (QURE) social dominance is up 21.83% from the previous month.
- uniQure N.V. (QURE) creators is up 86.32% from the previous week.
- uniQure N.V. (QURE) mentions is up 143.68% from the previous week.

### Price: $20.50
![Price Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:close/iv:1d.svg)  
[Price 24-Hour Time-Series Raw Data](/topic/$qure/time-series/close.tsv)  
The stock price has seen a significant increase, driven by positive news regarding the FDA Type A meeting for AMT-130 and renewed hope for accelerated approval, as reflected in increased social media engagement and positive sentiment. Unusual options activity shows significant call buying at the $70 strike, indicating strong bullish sentiment.  

24-Hour: -8.14%
7-Day: -17.98%
30-Day: -10.25%

1-Year High: $70.60 on 2025-10-29  
1-Year Low: $8.30 on 2025-04-08  
  
  
### AltRank: [---]
![AltRank Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:alt_rank/iv:1d.svg)  
[AltRank 24-Hour Time-Series Raw Data](/topic/$qure/time-series/alt_rank.tsv)  
uniQure N.V. (QURE) is currently AltRank #659 based on combined combined social and market metrics
Daily Average: [---]  
[--] Week: [---] +560  
[--] Month: [---] +324  
[--] Months: [---] +647  
[--] Year: [---] +27  
1-Year High: [-----] on 2026-01-28  
1-Year Low: [--] on 2025-09-27  
  
  
### Galaxy Score: [-----]
![Galaxy Score Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:galaxy_score/iv:1d.svg)  
[Galaxy Score 24-Hour Time-Series Raw Data](/topic/$qure/time-series/galaxy_score.tsv)  
Current Value: [-----]  
Daily Average: [--]  
[--] Week: [--] [---]  
[--] Month: [--] [---]  
1-Year High: [--] on 2026-01-09  
1-Year Low: [--] on 2025-12-11  
  
  
### Engagements: [------] (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/$qure/time-series/interactions.tsv)  
Current Value: [------]  
Daily Average: [------]  
[--] Week: [-------] -24%  
[--] Month: [---------] +1.50%  
[--] Months: [----------] +346%  
[--] Year: [----------] +506%  
1-Year High: [---------] on 2025-09-24  
1-Year Low: [-----] on 2025-03-08  

Engagements by network (24h):
News: [---]
Reddit: [--]
YouTube: [--]
X: [------]

  
  
### Mentions: [---] (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/$qure/time-series/posts_active.tsv)  
Current Value: [---]  
Daily Average: [---]  
[--] Week: [---] +144%  
[--] Month: [-----] -3.40%  
[--] Months: [------] +523%  
[--] Year: [------] +353%  
1-Year High: [-----] on 2025-09-25  
1-Year Low: [--] on 2025-04-07  

Mentions by network (24h):
News: [--]
Reddit: [--]
YouTube: [--]
X: [---]

  
  
### Creators: [---] (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/$qure/time-series/contributors_active.tsv)  
[---] unique social accounts have posts mentioning uniQure N.V. (QURE) in the last [--] hours which is down 5.80% from [---] in the previous [--] hours
Daily Average: [---]  
[--] Week: [---] +86%  
[--] Month: [---] -15%  
[--] Months: [-----] +353%  
[--] Year: [-----] +543%  
1-Year High: [-----] on 2025-09-25  
1-Year Low: [--] on 2025-04-07  

The most influential creators that mention uniQure N.V. in the last [--] hours

| Creator                                              | Rank | Followers | Posts | Engagements |
| -------                                              | ---- | --------- | ----- | ----------- |
| [@RNAiAnalyst](/creator/twitter/RNAiAnalyst)         | [--]    | [------]    | [--]     | [-----]       |
| [@AB1001_disciple](/creator/twitter/AB1001_disciple) | [--]    | [---]       | [--]     | [-----]       |
| [@Lucy3370](/creator/twitter/Lucy3370)               | [--]    | [-----]     | [--]     | [-----]       |
| [@TraderNorway](/creator/twitter/TraderNorway)       | [--]    | [---]       | [--]    | [-----]       |
| [@Andre_AGTC](/creator/twitter/Andre_AGTC)           | [--]    | [-----]     | [--]     | [-----]       |
| [@DesertDweller93](/creator/twitter/DesertDweller93) | [--]    | [-----]     | [--]     | [-----]       |
| [@from1to3000000](/creator/twitter/from1to3000000)   | [--]    | [-----]     | [--]     | [---]         |
| [@peter_mantas](/creator/twitter/peter_mantas)       | [--]    | [-----]     | [--]     | [---]         |
| [@jawnzilla](/creator/twitter/jawnzilla)             | [--]    | [---]       | [--]     | [---]         |
| [@biopharmacaster](/creator/twitter/biopharmacaster) | [--]   | [-----]     | [--]     | [---]         |

[View More](/list/creators/$qure/100)
  
  
### Sentiment: 76%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/$qure/time-series/sentiment.tsv)  
Current Value: 76%  
Daily Average: 83%  
[--] Week: 71% -20%  
[--] Month: 74% -2%  
[--] Months: 74% -18%  
[--] Year: 74% -13%  
1-Year High: 100% on 2025-03-14  
1-Year Low: 40% on 2025-04-14  

Most Supportive Themes:
- Positive Clinical Trial Results: (30%) Posts highlight recent positive clinical trial data, suggesting potential for future growth and success in the company's gene therapy treatments.
- Analyst Recommendations: (25%) Users are referencing positive analyst ratings and price targets, indicating a belief that the stock is currently undervalued.
- Stock Picks and Strategies: (20%) QURE is frequently recommended as a stock pick by users sharing investment strategies, suggesting confidence in its market performance.
  
Most Critical Themes:
- Concerns Over Clinical Trial Data Validity: (40%) Some posts express skepticism regarding the reliability of the clinical trial data and the potential for negative outcomes.
- Market Volatility Concerns: (35%) Users are discussing the impact of overall market conditions and potential volatility on QURE's stock price.
  
  
  
### Social Dominance: 0.02%
![Social Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:social_dominance/iv:1d.svg)  
[Social Dominance 24-Hour Time-Series Raw Data](/topic/$qure/time-series/social_dominance.tsv)  
Current Value: 0.02%  
Daily Average: 0.025%  
[--] Week: 0.033% +0.0042%  
[--] Month: 0.048% +0.0086%  
[--] Months: 0.048% +0.035%  
[--] Year: 0.048% +0.04%  
1-Year High: 0.228% on 2025-09-25  
1-Year Low: 0.0049% on 2025-04-07  
  
  
### Market Dominance: 0.00146%
![Market Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:market_dominance/iv:1d.svg)  
[Market Dominance 24-Hour Time-Series Raw Data](/topic/$qure/time-series/market_dominance.tsv)  
Current Value: 0.00146%  
Daily Average: 0%  
1-Year High: 0.116% on 2025-10-31  
1-Year Low: 0.00145% on 2026-02-13  
  
  
### Market Cap: $1,289,437,424
![Market Cap Line Chart](https://lunarcrush.com/gi/w:600/t:$qure/c:line/m:market_cap/iv:1d.svg)  
[Market Cap 24-Hour Time-Series Raw Data](/topic/$qure/time-series/market_cap.tsv)  
Current Value: $1,289,437,424  
Daily Average: $2,099,320,193  
[--] Week: $1,280,093,675 -18%  
[--] Month: $1,289,437,424 -7.40%  
1-Year High: $4,348,610,195 on 2025-10-29  
1-Year Low: $761,004,319 on 2025-09-19  

### Top uniQure N.V. News
Top news links shared on social in the last [--] hours  

*Showing a maximum of [--] news posts without a LunarCrush subscription.*  

"uniQure N.V. Ordinary Shares (QURE) Institutional Holdings Nasdaq Find the latest institutional holdings data for uniQure N.V. Ordinary Shares (QURE) including shareholders ownership summaries and holding activities at Nasdaq.com"  
[News Link](https://www.nasdaq.com/market-activity/stocks/qure/institutional-holdings) [@Nasdaq](/creator/x/Nasdaq) 2026-02-09T13:25Z 170.5K followers, [----] engagements


"uniQure Announces Updated Preliminary AMT-191 Phase I/IIa Data Showing Sustained Increases in -Gal A Enzyme Activity in Patients with Fabry Disease Supraphysiological expression of -Gal A activity maintained for over a year in longest treated patient as of data cutoff date  Stable Lyso-Gb3 levels maintained post-dosing regardless of enzyme replacement therapy status across all cohorts  Six of [--] patients have discontinued enzyme replacement therapy as of data cutoff date LEXINGTON Mass. and AMSTERDAM Feb. [--] [----] (GLOBE NEWSWIRE) -- uniQure N.V. (NASDAQ: QURE) a leading gene therapy company"  
[News Link](https://finance.yahoo.com/news/uniqure-announces-updated-preliminary-amt-120500052.html) [@YahooFinance](/creator/x/YahooFinance) 2026-02-06T12:51Z 2M followers, 11.9K engagements



### Top uniQure N.V. Social Posts
Top posts by engagements in the last [--] hours

*Showing a maximum of [--] top social posts without a LunarCrush subscription.*

"$beam $qure $mltx what to make of any positive regulatory 'alignments' when leftist saboteur Prasad can interject himself last minute $qure alignment e.g. last year occurred under new admin so this does not only impact developments started under old FDA"  
[X Link](https://x.com/RNAiAnalyst/status/2022606342842978549) [@RNAiAnalyst](/creator/x/RNAiAnalyst) 2026-02-14T09:38Z 21.2K followers, [----] engagements


"$QURE Analyst Target price for Today. 💸➡ https://discord.com/invite/z8jYkTU72W https://discord.com/invite/z8jYkTU72W"  
[X Link](https://x.com/Crypto_Update26/status/2022536677575790740) [@Crypto_Update26](/creator/x/Crypto_Update26) 2026-02-14T05:01Z [--] followers, [---] engagements


"So let's think on one of the probabilities measured in the AMT-130 trial. We have quite a rich array of studied endpoints (stick with me here - I'll disclose I think the FDA is using $QURE as a poster child for using Bayesian math rather than just shooting them down): https://www.uniqure.com/investors-media/press-releases https://www.uniqure.com/investors-media/press-releases"  
[X Link](https://x.com/jawnzilla/status/2022534046773903618) [@jawnzilla](/creator/x/jawnzilla) 2026-02-14T04:51Z [---] followers, [---] engagements


"Let's consider two facts: - $QURE went with a novel trial design wherein they have no placebo (basically barbaric to do with a lengthy invasive brain infusion procedure in a devastating and fast moving disease like Huntington) and rely on real world data from actual Huntington patients that have demographics comparable to those of trial patients. - New Bayesian guidance seems to QUITE explicitly allow for use of real world data as a prior probability. https://twitter.com/i/web/status/2022531983310537130 https://twitter.com/i/web/status/2022531983310537130"  
[X Link](https://x.com/jawnzilla/status/2022531983310537130) [@jawnzilla](/creator/x/jawnzilla) 2026-02-14T04:42Z [---] followers, [---] engagements

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