[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @NightOwlBiotech Night Owl Biotech Research Group Night Owl Biotech Research Group posts on X about $xbi, $jazz, $fold, $sndx the most. They currently have XXXXX followers and XXX posts still getting attention that total XXX engagements in the last XX hours. ### Engagements: XXX [#](/creator/twitter::1680659305698033664/interactions)  - X Week XXXXXX -XX% - X Month XXXXXX -XX% - X Months XXXXXXX +265% - X Year XXXXXXX +6,968% ### Mentions: XX [#](/creator/twitter::1680659305698033664/posts_active)  - X Week XX -XX% - X Month XX +2.60% - X Months XXX +160% - X Year XXX +1,350% ### Followers: XXXXX [#](/creator/twitter::1680659305698033664/followers)  - X Week XXXXX +3.30% - X Month XXXXX +12% - X Months XXXXX +208% ### CreatorRank: XXXXXXXXX [#](/creator/twitter::1680659305698033664/influencer_rank)  ### Social Influence [#](/creator/twitter::1680659305698033664/influence) --- **Social category influence** [stocks](/list/stocks) [cryptocurrencies](/list/cryptocurrencies) [finance](/list/finance) [countries](/list/countries) [currencies](/list/currencies) **Social topic influence** [$xbi](/topic/$xbi), [$jazz](/topic/$jazz), [$fold](/topic/$fold), [$sndx](/topic/$sndx), [$tars](/topic/$tars), [$tgtx](/topic/$tgtx), [$nbix](/topic/$nbix), [$apls](/topic/$apls), [$axsm](/topic/$axsm), [$srpt](/topic/$srpt) **Top assets mentioned** [Bitcoin Incognito (XBI)](/topic/$xbi) [Jazz Pharmaceuticals, Inc. (JAZZ)](/topic/$jazz) [Amicus Therapeutics, Inc (FOLD)](/topic/$fold) [TG Therapeutics, Inc. (TGTX)](/topic/$tgtx) [Neurocrine Biosciences, Inc. (NBIX)](/topic/$nbix) [Apellis Pharmaceuticals, Inc. Common Stock (APLS)](/topic/$apls) [Axsome Therapeutics, Inc (AXSM)](/topic/$axsm) [Sarepta Therapeutics, Inc. (SRPT)](/topic/$srpt) [SuperRare (RARE)](/topic/$rare) [SpringWorks Therapeutics, Inc. Common Stock (SWTX)](/topic/$swtx) [Intra-Cellular Therapies Inc. (ITCI)](/topic/$itci) [Madrigal Pharmaceuticals, Inc. Common Stock (MDGL)](/topic/$mdgl) [PTC Therapeutics, Inc. (PTCT)](/topic/$ptct) [Iovance Biotherapeutics, Inc. Common Stock (IOVA)](/topic/$iova) [Acadia Pharmaceuticals Inc. (ACAD)](/topic/$acad) [Corcept Therapeutics Inc. (CORT)](/topic/$cort) [Immunogen Inc (IMGN)](/topic/$imgn) [Agios Pharmaceuticals, Inc. (AGIO)](/topic/$agio) [Incyte Corporation (INCY)](/topic/$incy) [Exelixis Inc (EXEL)](/topic/$exel) [NovoCure Limited Ordinary Shares (NVCR)](/topic/$nvcr) [Geron Corp (GERN)](/topic/$gern) [Soleno Therapeutics, Inc. Common Stock (SLNO)](/topic/$slno) [Merus N.V. Common Shares (MRUS)](/topic/$mrus) [ImmunityBio, Inc. Common Stock (IBRX)](/topic/$ibrx) [Dawn Protocol (DAWN)](/topic/$dawn) [Ionis Pharmaceuticals, Inc. Common Stock (IONS)](/topic/$ions) [Alkermes Inc. plc (ALKS)](/topic/$alks) [BioMarin Pharmaceutical, Inc. (BMRN)](/topic/$bmrn) [Catalyst Pharmaceutical Inc. (CPRX)](/topic/$cprx) [BridgeBio Pharma, Inc. Common Stock (BBIO)](/topic/$bbio) [Insmed, Inc. (INSM)](/topic/$insm) [One Cash (ONC)](/topic/$onc) [Blueprint Medicines Corporation (BPMC)](/topic/$bpmc) [Morgan Stanley (MS)](/topic/morgan-stanley) [Scholar Rock Holding Corporation Common Stock (SRRK)](/topic/$srrk) [Summit Therapeutics Inc. Common Stock (SMMT)](/topic/$smmt) [Janux Therapeutics, Inc. Common Stock (JANX)](/topic/$janx) [Reata Pharmaceuticals, Inc. Class A Common Stock (RETA)](/topic/$reta) [Prothena Corporation plc Ordinary Shares (PRTA)](/topic/$prta) [Perrigo Company PLC (PRGO)](/topic/$prgo) ### Top Social Posts [#](/creator/twitter::1680659305698033664/posts) --- Top posts by engagements in the last XX hours "$FOLD was upgraded by Morgan Stanley this AM. Attached is a comparison of FOLD's 10-year revenue multiple v. peers (M&A & independents). $TARS & $APLS also trade at lower multiples (there may be good reason too) $XBI $AXSM $MDGL $ACAD $PTCT $MIRM $IONS $ALKS $CORT $SLNO $NBIX"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1945827086632993083) 2025-07-17 12:45:03 UTC 1178 followers, 2704 engagements "$INKT 's 1-day gain of XXX% appears to be a record going back to 1/1/2022 (post $XBI crash). Others north of XXX% since 1/1/2022 incl $VTGN $MNPR $PROK $SLNO $JSPR $SNTI $SRRK $PHVS $SYRE $CADL $SMMT $MDGL (watch dilutives) $CRBP $SPRO $BDTX $GYRE $JANX $NBTX $KALA $CMRX $RETA"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1944249350542045221) 2025-07-13 04:15:42 UTC 1178 followers, 3731 engagements "15 larger comm'l-stage bio valuations v. cumulative 10-year projected sales. Peers $IMGN $SWTX & X others were acquired @ XXXX - 0.78X 10-year projected sales (median = XXXX ave. =0.43) $RARE $SRPT $APLS $FOLD $HRMY $ANIP $NBIX $BMRN $JAZZ $AXSM $ACAD $PTCT $ASND $TGTX $MDGL"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1928935593481736501) 2025-05-31 22:04:18 UTC 1178 followers, 9010 engagements "$FOLD is X of the few comm'l-stage non-oncology focused bios whose share price has not recovered from $XBI lows of early April 2025. Should FOLD's share price not recover in line w/peers then FOLD needs to be acquired. $CPRX $BCRX $AGIO $MIRM $RARE $ACAD $TARS $ARQT $SPRY $TVTX"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1930609045498413210) 2025-06-05 12:54:00 UTC 1176 followers, 2273 engagements "$SNDX is up but off XX% since 7/16/24 Revuforj's projected sales profile (w/a 10/25 label exp) is consistent w/peers acq for $1.7-$2.2B (CTIC SRRA $KDMN $KYTH AGIO) 1st year Niktimvo sales $ projected to be XX% more than Rezurock acq for $1.9B. SNDX owns 1/3 of Niktimvo $XBI"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1947745795173646782) 2025-07-22 19:49:19 UTC 1174 followers, XXX engagements "93% of bios w/MCs $50+ are up since $XBI closed @ its 4/8/25 low. $PRTA is X of the worst over this time but there appears no news. PRTA has a Q225 P3 read so we suggest you look. Attached are all bios listed as from Ireland like PRTA so tariffs $ALKS $PRGO $GHRS $AVDL $MURA"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1917745571252576460) 2025-05-01 00:59:08 UTC 1177 followers, 2187 engagements "Comm'l-stage bio values as multiples of 10-year projected revenues v. recent peer M&A. $SRPT trades @ 0.12X cumulative 10-year projected analysts revenue est where $ITCI was acquired @ 0.41X. $XBI $NBI $IBBQ $RARE $APLS $FOLD $HRMY $ANIP $JAZZ $AXSM $NBIX $ACAD $PTCT $ASND $TGTX"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1926292767065436616) 2025-05-24 15:02:39 UTC 1177 followers, 6006 engagements "Expanded peer group showing market caps as multiples of cumulative 10-year analyst revenue estimates (some may or may not rely on new products) v. historic M&A peer group. More to come ASAP. $XBI $RARE $HRMY $APLS $FOLD $SRPT $NBIX $PTCT $JAZZ $AXSM $TGTX $ASND $ITCI $IMGN"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1919545615651873016) 2025-05-06 00:11:52 UTC 1177 followers, 2826 engagements "FY26 multiples for all XX comm'l-stage (& pre) oncology (MCs $200MM+) & all XX non-oncology (MCs $600MM+) focused bios $IOVA data in certain lung cancers imminent We'd guess M&A candidates incl $TARS $AGIO $JAZZ $TVTX $FOLD $TGTX $SNDX via $INCY $MRUS $BBIO $CORT $IONS $INSM"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1944063284342403080) 2025-07-12 15:56:20 UTC 1178 followers, 4324 engagements "17 of all XX comm'l-stage oncology focused bios $200MM+ MC are off 10%+ from 1H 6/2025 highs while $XBI is off 3%. Why We'll post non-oncology next $ONC $GMAB $INCY $EXEL $JAZZ $LEGN $MRUS $IBRX $NVCR $IMCR $GERN $ZYME $FENC $IOVA $KURA $URGN $NUVB $REPL $DCTH $RIGL $SNDX $CTOR"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1936813714809946338) 2025-06-22 15:49:08 UTC 1177 followers, 3080 engagements "We added $SRRA to our list of peer M&A as it was acquired pre FDA approval $KURA but nonetheless @ roughly the same multiple. Oncology still trails non-oncology even on a good day. $VSTM $TARS $ARDX $FOLD $DAWN $SNDX $XBI $NBI"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1940422906162684324) 2025-07-02 14:50:46 UTC 1178 followers, 3889 engagements "$VRNA is being acq by $MRK @ 0.45X 10-year analyst consensus sales ests ($10B EV). This appears on the high end v peers. VRNA will file a 14D9 in X weeks w/projected sales provided MRK that may differ from analysts $TARS $SNDX have recent approvals $FOLD $ARDX $TVTX $MIRM $XBI"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1942983664054276306) 2025-07-09 16:26:19 UTC 1175 followers, 5432 engagements "FY28 (Year 4) revenue multiples of comm'l-stage non-oncology focused bios w/$1B+ MC + $ARDX b/c it trades @ a low multiple (w/FY34 patent exp). $ITCI was acq @ 5.5X & $SWTX @ 2.6X $XBI $SRPT $PCRX $HRMY $JAZZ $APLS $TVTX $TARS $RARE $BHVN $ARQT $AXSM $NBIX $BCRX $AUPH $AGIO $SPRY"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1926324810226786386) 2025-05-24 17:09:58 UTC 1177 followers, 6789 engagements "Top shows EVs paid as multiples of cumulative 10-year projected revenues/GM from XX recent larger comm'l-stage bio M&A. Range = 0.26X $SWTX - 0.78X $IMGN Bottom shows like multiples of pot'l M&A candidates $FOLD $RARE $APLS $TARS $AXSM $JAZZ $BMRN $MDGL $PTCT $ASND $TGTX $NBIX"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1935371443212271740) 2025-06-18 16:18:04 UTC 1175 followers, 2658 engagements "Centerview notes a peer median year X M&A revenue multiple of 1.7X in the $CMRX peer group v. 6.0X in $MRTX (see snapshots). 10-year revenue forecasts suggest the higher the revenue $ the higher the multiple $SWTX $TGTX $MDGL $CYTK $AVDL $XERS $ARDX $SPRY $HROW $PHAT $ESPR $AUPH"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1903831053741015379) 2025-03-23 15:27:49 UTC 1178 followers, 14.7K engagements "FY28 (Year 4) multiples of comm'l-stage oncology focused bios w/MCs $400MM+. $ITCI was acq @ 5.5X FY28 & $SWTX @ 2.6X. $XBI $NBI $IOVA $AUTL $DAWN $JAZZ $GERN $SNDX $LEGN $INCY $NVCR $GMAB $IMCR $IBRX $ONC $DCTH $EXEL $BPMC $ZYME $TLX $MRUS. PDUFAs = $REPL $NUVB $VSTM (P2) $CRDF"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1926331827553251710) 2025-05-24 17:37:51 UTC 1175 followers, 10.9K engagements "$NVCR reported Q225 sales this morning. NVCR trades at XXX - $3.0X FY2025 consensus which is lower than peer $EXEL at 5.0X+ & $LEGN at 7.0X+ (though NVCR gross margins are in the 70s where most peers are in the 90s). $XBI $NBI"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1948375421457711489) 2025-07-24 13:31:14 UTC 1177 followers, XXX engagements "$NBIX $SRPT & $JAZZ trade at multiples of 10-year analyst revenue estimates that are meaningfully lower than multiples paid to acquire peers (of course analyst estimates could be wrong). NBIX multiples do not reflect its $2B cash. $HRMY & $APLS also provided. $XBI $ITCI $IMGN"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1913318313167298995) 2025-04-18 19:46:48 UTC 1177 followers, 2353 engagements "$SNDX $INCY Niktimvo US sales forecast using $RPRX data points in its 11/24 investor deck To repay $822.5MM (2.35X the $350MM invested) via XXXX% royalties requires $5.96B in cumulative FY25-38 sales Royalties noted would = XXXX% IRR v "low single-digits" per RPRX Pushback"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1948855624022048855) 2025-07-25 21:19:23 UTC 1178 followers, XXX engagements "All XX comm'l-stage oncology focused bios v. all XX non-oncology w/MCs $1.5B+ & v. all XX w/MCs $160MM to $1.5B. Oncology as a whole trades @ lower FY28 multiples & have fared worse as a peer group YTD $XBI $NBI $IOVA $JAZZ $LEGN $GMAB $SNDX $ARGX $BBIO $CORT $KNSA $TWST $SPRY"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1947016379896385898) 2025-07-20 19:30:53 UTC 1177 followers, 3155 engagements "The next 2-3 weeks are the most exciting every quarter. 1st comm'l-stage oncology focused bio to report Q2 sales & update guidance this coming Thursday = $NVCR. $SNDX s/b next on 8/1/25 Attached see SP chge since 5/19/25 (after Q125 earnings). $DCTH $AUTL $GERN $DAWN $IMCR $XBI"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1946644840424382944) 2025-07-19 18:54:31 UTC 1178 followers, 2350 engagements "$TARS trades @ 0.17X 10-year analyst consensus revenue ests (as of 6/10/25). Attached are like multiples paid in XX peer comm'l-stage bio M&A trxs. "Mid-size" peer group were acq @ a median 0.40X multiple (but range from XXXX - 0.78X). $BPMC $SWTX $ITCI $ARQT $AGIO $XBI $NBI"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1932614817518420148) 2025-06-11 01:44:13 UTC 1177 followers, 2478 engagements "Table notes the share price today v. @ FDA approval date for all XXX new comm'l-stage non-oncology focused bios since 1/1/13. These are tracked manually so o/c we may have missed X or X (or a split). $XBI Biggest winners: $VCEL $CPRX $ADMA $INSM $ZEAL $TGTX $LQDA $ALNY $RYTM"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1946950812783010219) 2025-07-20 15:10:21 UTC 1176 followers, 8659 engagements "Changes ($%) for all XX comm'l-stage oncology & XX non-oncology (MC $500MM+) bios since 6/28/24. Non-oncology clearly outperformed Biggest winners $VRNA $AKBA $CRMD $RIGL $CORT $SPRY $XERS $TGTX $SLNO $EXEL $TVTX Losers $SRPT $XFOR $IOVA $ADAP $KURA $MGNX $KPTI $GERN $IBRX"  [@NightOwlBiotech](/creator/x/NightOwlBiotech) on [X](/post/tweet/1939050544506507492) 2025-06-28 19:57:30 UTC 1178 followers, 3802 engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@NightOwlBiotech Night Owl Biotech Research Group
Night Owl Biotech Research Group posts on X about $xbi, $jazz, $fold, $sndx the most. They currently have XXXXX followers and XXX posts still getting attention that total XXX engagements in the last XX hours.
Engagements: XXX #
- X Week XXXXXX -XX%
- X Month XXXXXX -XX%
- X Months XXXXXXX +265%
- X Year XXXXXXX +6,968%
Mentions: XX #
- X Week XX -XX%
- X Month XX +2.60%
- X Months XXX +160%
- X Year XXX +1,350%
Followers: XXXXX #
- X Week XXXXX +3.30%
- X Month XXXXX +12%
- X Months XXXXX +208%
CreatorRank: XXXXXXXXX #
Social Influence #
Social category influence stocks cryptocurrencies finance countries currencies
Social topic influence $xbi, $jazz, $fold, $sndx, $tars, $tgtx, $nbix, $apls, $axsm, $srpt
Top assets mentioned Bitcoin Incognito (XBI) Jazz Pharmaceuticals, Inc. (JAZZ) Amicus Therapeutics, Inc (FOLD) TG Therapeutics, Inc. (TGTX) Neurocrine Biosciences, Inc. (NBIX) Apellis Pharmaceuticals, Inc. Common Stock (APLS) Axsome Therapeutics, Inc (AXSM) Sarepta Therapeutics, Inc. (SRPT) SuperRare (RARE) SpringWorks Therapeutics, Inc. Common Stock (SWTX) Intra-Cellular Therapies Inc. (ITCI) Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) PTC Therapeutics, Inc. (PTCT) Iovance Biotherapeutics, Inc. Common Stock (IOVA) Acadia Pharmaceuticals Inc. (ACAD) Corcept Therapeutics Inc. (CORT) Immunogen Inc (IMGN) Agios Pharmaceuticals, Inc. (AGIO) Incyte Corporation (INCY) Exelixis Inc (EXEL) NovoCure Limited Ordinary Shares (NVCR) Geron Corp (GERN) Soleno Therapeutics, Inc. Common Stock (SLNO) Merus N.V. Common Shares (MRUS) ImmunityBio, Inc. Common Stock (IBRX) Dawn Protocol (DAWN) Ionis Pharmaceuticals, Inc. Common Stock (IONS) Alkermes Inc. plc (ALKS) BioMarin Pharmaceutical, Inc. (BMRN) Catalyst Pharmaceutical Inc. (CPRX) BridgeBio Pharma, Inc. Common Stock (BBIO) Insmed, Inc. (INSM) One Cash (ONC) Blueprint Medicines Corporation (BPMC) Morgan Stanley (MS) Scholar Rock Holding Corporation Common Stock (SRRK) Summit Therapeutics Inc. Common Stock (SMMT) Janux Therapeutics, Inc. Common Stock (JANX) Reata Pharmaceuticals, Inc. Class A Common Stock (RETA) Prothena Corporation plc Ordinary Shares (PRTA) Perrigo Company PLC (PRGO)
Top Social Posts #
Top posts by engagements in the last XX hours
"$FOLD was upgraded by Morgan Stanley this AM. Attached is a comparison of FOLD's 10-year revenue multiple v. peers (M&A & independents). $TARS & $APLS also trade at lower multiples (there may be good reason too) $XBI $AXSM $MDGL $ACAD $PTCT $MIRM $IONS $ALKS $CORT $SLNO $NBIX"
@NightOwlBiotech on X 2025-07-17 12:45:03 UTC 1178 followers, 2704 engagements
"$INKT 's 1-day gain of XXX% appears to be a record going back to 1/1/2022 (post $XBI crash). Others north of XXX% since 1/1/2022 incl $VTGN $MNPR $PROK $SLNO $JSPR $SNTI $SRRK $PHVS $SYRE $CADL $SMMT $MDGL (watch dilutives) $CRBP $SPRO $BDTX $GYRE $JANX $NBTX $KALA $CMRX $RETA" @NightOwlBiotech on X 2025-07-13 04:15:42 UTC 1178 followers, 3731 engagements
"15 larger comm'l-stage bio valuations v. cumulative 10-year projected sales. Peers $IMGN $SWTX & X others were acquired @ XXXX - 0.78X 10-year projected sales (median = XXXX ave. =0.43) $RARE $SRPT $APLS $FOLD $HRMY $ANIP $NBIX $BMRN $JAZZ $AXSM $ACAD $PTCT $ASND $TGTX $MDGL" @NightOwlBiotech on X 2025-05-31 22:04:18 UTC 1178 followers, 9010 engagements
"$FOLD is X of the few comm'l-stage non-oncology focused bios whose share price has not recovered from $XBI lows of early April 2025. Should FOLD's share price not recover in line w/peers then FOLD needs to be acquired. $CPRX $BCRX $AGIO $MIRM $RARE $ACAD $TARS $ARQT $SPRY $TVTX" @NightOwlBiotech on X 2025-06-05 12:54:00 UTC 1176 followers, 2273 engagements
"$SNDX is up but off XX% since 7/16/24 Revuforj's projected sales profile (w/a 10/25 label exp) is consistent w/peers acq for $1.7-$2.2B (CTIC SRRA $KDMN $KYTH AGIO) 1st year Niktimvo sales $ projected to be XX% more than Rezurock acq for $1.9B. SNDX owns 1/3 of Niktimvo $XBI" @NightOwlBiotech on X 2025-07-22 19:49:19 UTC 1174 followers, XXX engagements
"93% of bios w/MCs $50+ are up since $XBI closed @ its 4/8/25 low. $PRTA is X of the worst over this time but there appears no news. PRTA has a Q225 P3 read so we suggest you look. Attached are all bios listed as from Ireland like PRTA so tariffs $ALKS $PRGO $GHRS $AVDL $MURA" @NightOwlBiotech on X 2025-05-01 00:59:08 UTC 1177 followers, 2187 engagements
"Comm'l-stage bio values as multiples of 10-year projected revenues v. recent peer M&A. $SRPT trades @ 0.12X cumulative 10-year projected analysts revenue est where $ITCI was acquired @ 0.41X. $XBI $NBI $IBBQ $RARE $APLS $FOLD $HRMY $ANIP $JAZZ $AXSM $NBIX $ACAD $PTCT $ASND $TGTX" @NightOwlBiotech on X 2025-05-24 15:02:39 UTC 1177 followers, 6006 engagements
"Expanded peer group showing market caps as multiples of cumulative 10-year analyst revenue estimates (some may or may not rely on new products) v. historic M&A peer group. More to come ASAP. $XBI $RARE $HRMY $APLS $FOLD $SRPT $NBIX $PTCT $JAZZ $AXSM $TGTX $ASND $ITCI $IMGN" @NightOwlBiotech on X 2025-05-06 00:11:52 UTC 1177 followers, 2826 engagements
"FY26 multiples for all XX comm'l-stage (& pre) oncology (MCs $200MM+) & all XX non-oncology (MCs $600MM+) focused bios $IOVA data in certain lung cancers imminent We'd guess M&A candidates incl $TARS $AGIO $JAZZ $TVTX $FOLD $TGTX $SNDX via $INCY $MRUS $BBIO $CORT $IONS $INSM" @NightOwlBiotech on X 2025-07-12 15:56:20 UTC 1178 followers, 4324 engagements
"17 of all XX comm'l-stage oncology focused bios $200MM+ MC are off 10%+ from 1H 6/2025 highs while $XBI is off 3%. Why We'll post non-oncology next $ONC $GMAB $INCY $EXEL $JAZZ $LEGN $MRUS $IBRX $NVCR $IMCR $GERN $ZYME $FENC $IOVA $KURA $URGN $NUVB $REPL $DCTH $RIGL $SNDX $CTOR" @NightOwlBiotech on X 2025-06-22 15:49:08 UTC 1177 followers, 3080 engagements
"We added $SRRA to our list of peer M&A as it was acquired pre FDA approval $KURA but nonetheless @ roughly the same multiple. Oncology still trails non-oncology even on a good day. $VSTM $TARS $ARDX $FOLD $DAWN $SNDX $XBI $NBI" @NightOwlBiotech on X 2025-07-02 14:50:46 UTC 1178 followers, 3889 engagements
"$VRNA is being acq by $MRK @ 0.45X 10-year analyst consensus sales ests ($10B EV). This appears on the high end v peers. VRNA will file a 14D9 in X weeks w/projected sales provided MRK that may differ from analysts $TARS $SNDX have recent approvals $FOLD $ARDX $TVTX $MIRM $XBI" @NightOwlBiotech on X 2025-07-09 16:26:19 UTC 1175 followers, 5432 engagements
"FY28 (Year 4) revenue multiples of comm'l-stage non-oncology focused bios w/$1B+ MC + $ARDX b/c it trades @ a low multiple (w/FY34 patent exp). $ITCI was acq @ 5.5X & $SWTX @ 2.6X $XBI $SRPT $PCRX $HRMY $JAZZ $APLS $TVTX $TARS $RARE $BHVN $ARQT $AXSM $NBIX $BCRX $AUPH $AGIO $SPRY" @NightOwlBiotech on X 2025-05-24 17:09:58 UTC 1177 followers, 6789 engagements
"Top shows EVs paid as multiples of cumulative 10-year projected revenues/GM from XX recent larger comm'l-stage bio M&A. Range = 0.26X $SWTX - 0.78X $IMGN Bottom shows like multiples of pot'l M&A candidates $FOLD $RARE $APLS $TARS $AXSM $JAZZ $BMRN $MDGL $PTCT $ASND $TGTX $NBIX" @NightOwlBiotech on X 2025-06-18 16:18:04 UTC 1175 followers, 2658 engagements
"Centerview notes a peer median year X M&A revenue multiple of 1.7X in the $CMRX peer group v. 6.0X in $MRTX (see snapshots). 10-year revenue forecasts suggest the higher the revenue $ the higher the multiple $SWTX $TGTX $MDGL $CYTK $AVDL $XERS $ARDX $SPRY $HROW $PHAT $ESPR $AUPH" @NightOwlBiotech on X 2025-03-23 15:27:49 UTC 1178 followers, 14.7K engagements
"FY28 (Year 4) multiples of comm'l-stage oncology focused bios w/MCs $400MM+. $ITCI was acq @ 5.5X FY28 & $SWTX @ 2.6X. $XBI $NBI $IOVA $AUTL $DAWN $JAZZ $GERN $SNDX $LEGN $INCY $NVCR $GMAB $IMCR $IBRX $ONC $DCTH $EXEL $BPMC $ZYME $TLX $MRUS. PDUFAs = $REPL $NUVB $VSTM (P2) $CRDF" @NightOwlBiotech on X 2025-05-24 17:37:51 UTC 1175 followers, 10.9K engagements
"$NVCR reported Q225 sales this morning. NVCR trades at XXX - $3.0X FY2025 consensus which is lower than peer $EXEL at 5.0X+ & $LEGN at 7.0X+ (though NVCR gross margins are in the 70s where most peers are in the 90s). $XBI $NBI" @NightOwlBiotech on X 2025-07-24 13:31:14 UTC 1177 followers, XXX engagements
"$NBIX $SRPT & $JAZZ trade at multiples of 10-year analyst revenue estimates that are meaningfully lower than multiples paid to acquire peers (of course analyst estimates could be wrong). NBIX multiples do not reflect its $2B cash. $HRMY & $APLS also provided. $XBI $ITCI $IMGN" @NightOwlBiotech on X 2025-04-18 19:46:48 UTC 1177 followers, 2353 engagements
"$SNDX $INCY Niktimvo US sales forecast using $RPRX data points in its 11/24 investor deck To repay $822.5MM (2.35X the $350MM invested) via XXXX% royalties requires $5.96B in cumulative FY25-38 sales Royalties noted would = XXXX% IRR v "low single-digits" per RPRX Pushback" @NightOwlBiotech on X 2025-07-25 21:19:23 UTC 1178 followers, XXX engagements
"All XX comm'l-stage oncology focused bios v. all XX non-oncology w/MCs $1.5B+ & v. all XX w/MCs $160MM to $1.5B. Oncology as a whole trades @ lower FY28 multiples & have fared worse as a peer group YTD $XBI $NBI $IOVA $JAZZ $LEGN $GMAB $SNDX $ARGX $BBIO $CORT $KNSA $TWST $SPRY" @NightOwlBiotech on X 2025-07-20 19:30:53 UTC 1177 followers, 3155 engagements
"The next 2-3 weeks are the most exciting every quarter. 1st comm'l-stage oncology focused bio to report Q2 sales & update guidance this coming Thursday = $NVCR. $SNDX s/b next on 8/1/25 Attached see SP chge since 5/19/25 (after Q125 earnings). $DCTH $AUTL $GERN $DAWN $IMCR $XBI" @NightOwlBiotech on X 2025-07-19 18:54:31 UTC 1178 followers, 2350 engagements
"$TARS trades @ 0.17X 10-year analyst consensus revenue ests (as of 6/10/25). Attached are like multiples paid in XX peer comm'l-stage bio M&A trxs. "Mid-size" peer group were acq @ a median 0.40X multiple (but range from XXXX - 0.78X). $BPMC $SWTX $ITCI $ARQT $AGIO $XBI $NBI" @NightOwlBiotech on X 2025-06-11 01:44:13 UTC 1177 followers, 2478 engagements
"Table notes the share price today v. @ FDA approval date for all XXX new comm'l-stage non-oncology focused bios since 1/1/13. These are tracked manually so o/c we may have missed X or X (or a split). $XBI Biggest winners: $VCEL $CPRX $ADMA $INSM $ZEAL $TGTX $LQDA $ALNY $RYTM" @NightOwlBiotech on X 2025-07-20 15:10:21 UTC 1176 followers, 8659 engagements
"Changes ($%) for all XX comm'l-stage oncology & XX non-oncology (MC $500MM+) bios since 6/28/24. Non-oncology clearly outperformed Biggest winners $VRNA $AKBA $CRMD $RIGL $CORT $SPRY $XERS $TGTX $SLNO $EXEL $TVTX Losers $SRPT $XFOR $IOVA $ADAP $KURA $MGNX $KPTI $GERN $IBRX" @NightOwlBiotech on X 2025-06-28 19:57:30 UTC 1178 followers, 3802 engagements