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# Agios Pharmaceuticals, Inc. (AGIO)

Agios Pharmaceuticals (AGIO) stock sees volatility as FDA review of mitapivat for Thalassemia continues post-PDUFA date, while mixed Phase X sickle cell trial results weigh on sentiment.

### About Agios Pharmaceuticals, Inc.
Agios Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing therapies for rare genetic diseases and cancer.  
Agios Pharmaceuticals, Inc. uses the ticker $AGIO for trading. Listed in the [Stocks](/list/stocks) category within the [Healthcare](/list/stocks/healthcare) sectors.

### Insights
- Agios Pharmaceuticals, Inc. (AGIO) Galaxy Score™ is up XXXXX% from the previous X months.
- Agios Pharmaceuticals, Inc. (AGIO) sentiment is up XXXXXX% from the previous week.

### Price: $XXXXX
![Price Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:close/iv:1d.svg)  
[Price 24-Hour Time-Series Raw Data](/topic/$agio/time-series/close.tsv)  
The stock price has experienced a significant decrease, primarily driven by the mixed Phase X trial results for their sickle cell drug, which failed to meet key endpoints. This negative news has overshadowed positive developments like the CHMP opinion and analyst price targets.  

24-Hour: XXXX%
7-Day: XXXX%
30-Day: -XXXXX%

1-Year High: $XXXXX on 2025-11-18  
1-Year Low: $XXXXX on 2025-11-19  
  
  
### AltRank: XXXXX
![AltRank Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:alt_rank/iv:1d.svg)  
[AltRank 24-Hour Time-Series Raw Data](/topic/$agio/time-series/alt_rank.tsv)  
Agios Pharmaceuticals, Inc. (AGIO) is currently AltRank #1,303 based on combined combined social and market metrics
Daily Average: XXX  
X Week: XXXXX +450  
X Month: XXXXX +263  
X Months: XXXXX +565  
X Year: XXXXX +1,115  
1-Year High: XXXXX on 2025-08-03  
1-Year Low: X on 2024-12-29  
  
  
### Galaxy Score: XXXXX
![Galaxy Score Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:galaxy_score/iv:1d.svg)  
[Galaxy Score 24-Hour Time-Series Raw Data](/topic/$agio/time-series/galaxy_score.tsv)  
Current Value: XXXXX  
Daily Average: XX  
X Week: XX +24  
X Month: XX +12  
X Months: XX -X  
X Year: XX -X  
1-Year High: XX on 2025-06-26  
1-Year Low: X on 2025-08-28  
  
  
### Engagements: XXXXX (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/$agio/time-series/interactions.tsv)  
Current Value: XXXXX  
Daily Average: XXXXX  
X Week: XXXXXX -XX%  
X Month: XXXXXXX +868%  
X Months: XXXXXXXXX +47%  
X Year: XXXXXXXXX -XX%  
1-Year High: XXXXXX on 2025-11-19  
1-Year Low: XXX on 2025-04-20  

Engagements by network (24h):
X: XXXXX

  
  
### Mentions: XX (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/$agio/time-series/posts_active.tsv)  
Current Value: XX  
Daily Average: XX  
X Week: XXX -XX%  
X Month: XXX +114%  
X Months: XXXXX +56%  
X Year: XXXXX -XX%  
1-Year High: XXX on 2025-11-26  
1-Year Low: XX on 2025-04-19  

Mentions by network (24h):
X: XXX

  
  
### Creators: XX (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/$agio/time-series/contributors_active.tsv)  
XX unique social accounts have posts mentioning Agios Pharmaceuticals, Inc. (AGIO) in the last XX hours which is down XX% from XX in the previous XX hours
Daily Average: XX  
X Week: XXX -XX%  
X Month: XXX +190%  
X Months: XXXXX +184%  
X Year: XXXXX +140%  
1-Year High: XXX on 2025-06-28  
1-Year Low: X on 2025-04-21  

The most influential creators that mention Agios Pharmaceuticals, Inc. in the last XX hours

| Creator                                              | Rank | Followers | Posts | Engagements |
| -------                                              | ---- | --------- | ----- | ----------- |
| [@seedy19tron](/creator/twitter/seedy19tron)         | X    | XXXXX     | X     | XXX         |
| [@Fredbenz0](/creator/twitter/Fredbenz0)             | X    | XXXXX     | X     | XXX         |
| [@TheOptionsBull2](/creator/twitter/TheOptionsBull2) | X    | XXX       | X     | XXX         |
| [@Ssunten_](/creator/twitter/Ssunten_)               | X    | XXX       | X     | XX          |
| [@seedytx19](/creator/twitter/seedytx19)             | X    | XXXXX     | X     | XX          |

[View More](/list/creators/$agio/100)
  
  
### Sentiment: XXX%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/$agio/time-series/sentiment.tsv)  
Current Value: XXX%  
Daily Average: XX%  
X Week: XXX% +64%  
X Month: XXX% +60%  
X Months: XXX% +10%  
X Year: XXX% +51%  
1-Year High: XXX% on 2025-02-22  
1-Year Low: XX% on 2025-09-08  

Most Supportive Themes:
- Positive CHMP Opinion: (20%) Agios Pharmaceuticals received a positive opinion from the CHMP for PYRUKYND, a significant step towards global approvals.
- Analyst Price Targets: (15%) Analysts are issuing price targets for Agios Pharmaceuticals, indicating potential upside and investor interest.
  
Most Critical Themes:
- Mixed Phase X Trial Results: (50%) The stock price has seen a significant decrease, likely due to mixed Phase X trial results for their sickle cell drug, which failed to meet statistical significance on key endpoints.
- Risk Factors Update: (10%) Agios Pharmaceuticals' 10-Q filing highlights significant risks including reliance on PYRUKYND success, competition, and financial volatility.
  
  
  
### Social Dominance: XXXXXXX%
![Social Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:social_dominance/iv:1d.svg)  
[Social Dominance 24-Hour Time-Series Raw Data](/topic/$agio/time-series/social_dominance.tsv)  
Current Value: XXXXXXX%  
Daily Average: XXXXX%  
X Week: XXXXXX% -XXXXXX%  
X Month: XXXXXX% -XXXXXX%  
X Months: XXXXXX% +0.0012%  
X Year: XXXXXX% -XXXXX%  
1-Year High: XXXXX% on 2024-12-26  
1-Year Low: XXXXXX% on 2025-10-24  
  
  
### Market Dominance: XXXXXXX%
![Market Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:market_dominance/iv:1d.svg)  
[Market Dominance 24-Hour Time-Series Raw Data](/topic/$agio/time-series/market_dominance.tsv)  
Current Value: XXXXXXX%  
Daily Average: X%  
1-Year High: XXXXX% on 2025-11-18  
1-Year Low: XXXXXXX% on 2025-12-10  
  
  
### Market Cap: $XXXXXXXXXXXXX
![Market Cap Line Chart](https://lunarcrush.com/gi/w:600/t:$agio/c:line/m:market_cap/iv:1d.svg)  
[Market Cap 24-Hour Time-Series Raw Data](/topic/$agio/time-series/market_cap.tsv)  
Current Value: $XXXXXXXXXXXXX  
Daily Average: $XXXXXXXXXXXXX  
X Week: $XXXXXXXXXXXXX no change  
X Month: $XXXXXXXXXXXXX -$34%  
X Months: $XXXXXXXXXXXXX -$21%  
X Year: $XXXXXXXXXXXXX -$43%  
1-Year High: $XXXXXXXXXXXXX on 2025-11-18  
1-Year Low: $XXXXXXXXXXXXX on 2025-11-19  

### Top Agios Pharmaceuticals, Inc. Social Posts
Top posts by engagements in the last XX hours

*Showing only X posts for non-authenticated requests. Use your API key in requests for full results.*

"$OCUL $SAIL $SMMT $SOC $SATS $BYND $LCID $RDW $CAPR $NKE $RZLV $ORCL $SNDK $SLS $INSE $HNST $IMMX $AGIO $CCOI $SKYT $CSIQ $KSS $JSPR $CETX $PATH $SEI $SOLV $UNFI 💎 12/08/25-Part X 💎Top Unusual Implied Volatility Watchlist & Database 💎IV Change Details For 100+ Stocks (Secondary Unusual Options Alert)"  
[X Link](https://x.com/Fredbenz0/status/1998403189813498054) [@Fredbenz0](/creator/x/Fredbenz0) 2025-12-09T14:43Z 2692 followers, XXX engagements


"$AGIO +0.87% today as Agios Provides Update on U.S. sNDA for Mitapivat in Thalassemia More Info:"  
[X Link](https://x.com/OzmosiHealth/status/1998048681417703520) [@OzmosiHealth](/creator/x/OzmosiHealth) 2025-12-08T15:15Z 3011 followers, XXX engagements


"$CFLT $KYMR $COGT $AVGO $AGIO $CRWV $ITT $MRVL $TSLA PRE-MARKET MOVERS: Currently Higher: - Kymera Therapeutics (KYMR) up XXXX% after reporting clinical results from the BroADen Phase 1b atopic dermatitis clinical trial of KT-621 - Cogent Biosciences (COGT) up XXXX% after announcing results of APEX trial of bezuclastinib - Confluent (CFLT) up XXXX% after entering into a definitive agreement under which IBM (IBM) will acquire all of the issued and outstanding common shares of the company for $XX per share - Broadcom (AVGO) up XXX% after The Information reported Microsoft (MSFT) is in talks to"  
[X Link](https://x.com/CorleoneDon77/status/1998031428135579888) [@CorleoneDon77](/creator/x/CorleoneDon77) 2025-12-08T14:06Z 6606 followers, XXX engagements


"Morning Movers: Confluent surges following deal to be bought by IBM $CFLT $KYMR $AVGO $AGIO $CRWV $ITT $MRVL $TSLA"  
[X Link](https://x.com/theflynews/status/1998030047069012045) [@theflynews](/creator/x/theflynews) 2025-12-08T14:00Z 28.8K followers, XXX engagements