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# Ionis Pharmaceuticals, Inc. Common Stock (IONS)

Metagenomi will present preclinical data supporting a new collaboration target of APOC3 with Ionis Pharmaceuticals at an upcoming Nature Conference. This news follows recent analyst upgrades and positive trial results.

### About Ionis Pharmaceuticals, Inc. Common Stock
Ionis Pharmaceuticals, Inc. is a biotechnology company focused on developing RNA-targeted therapeutics.  
Ionis Pharmaceuticals, Inc. Common Stock uses the ticker $IONS for trading. Listed in the [Stocks](/list/stocks) category within the [Healthcare](/list/stocks/healthcare) sectors.

### Insights
- Ionis Pharmaceuticals, Inc. Common Stock (IONS) social dominance hit XXXXXX which is XXX% higher than it's daily average.
- Ionis Pharmaceuticals, Inc. Common Stock (IONS) trading volume is up XXXXXX% from the previous X months.
- Ionis Pharmaceuticals, Inc. Common Stock (IONS) sentiment is up XXXXX% from the previous year.

### Price: $XXXXX
![Price Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:close/iv:1d.svg)  
[Price 24-Hour Time-Series Raw Data](/topic/$ions/time-series/close.tsv)  
The stock price is experiencing a significant surge, hitting a 52-week high, driven by positive analyst sentiment, strong Q3 earnings, and promising Phase X trial results for key drugs. This positive momentum is outweighing a minor FDA hold, and social media sentiment is overwhelmingly positive.  

24-Hour: -XXXX%
7-Day: -XXXX%
30-Day: XXXX%

1-Year High: $XXXXX on 2025-11-28  
1-Year Low: $XXXXX on 2025-04-08  
  
  
### AltRank: XXX
![AltRank Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:alt_rank/iv:1d.svg)  
[AltRank 24-Hour Time-Series Raw Data](/topic/$ions/time-series/alt_rank.tsv)  
Ionis Pharmaceuticals, Inc. Common Stock (IONS) is currently AltRank #634 based on combined combined social and market metrics
Daily Average: XXX  
X Week: XXX -XXX  
X Month: XXX -XXX  
X Months: XXX -XXX  
X Year: XXX +80  
1-Year High: XXXXX on 2025-08-06  
1-Year Low: XX on 2025-01-11  
  
  
### Galaxy Score: XXXXX
![Galaxy Score Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:galaxy_score/iv:1d.svg)  
[Galaxy Score 24-Hour Time-Series Raw Data](/topic/$ions/time-series/galaxy_score.tsv)  
Current Value: XXXXX  
Daily Average: XX  
X Week: XX no change  
X Month: XX +2  
X Months: XX -X  
X Year: XX -XX  
1-Year High: XX on 2025-04-07  
1-Year Low: XX on 2025-07-08  
  
  
### Engagements: XXXXX (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/$ions/time-series/interactions.tsv)  
Current Value: XXXXX  
Daily Average: XXXXXX  
X Week: XXXXXX -XX%  
X Month: XXXXXXX +25%  
X Months: XXXXXXXXX +41%  
X Year: XXXXXXXXX +123%  
1-Year High: XXXXXXX on 2025-02-19  
1-Year Low: XXXXX on 2025-03-09  

Engagements by network (24h):
News: XXX
Reddit: XX
X: XXXXX
YouTube: XXXXX

  
  
### Mentions: XX (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/$ions/time-series/posts_active.tsv)  
Current Value: XX  
Daily Average: XXX  
X Week: XXX -XX%  
X Month: XXXXX +57%  
X Months: XXXXX +81%  
X Year: XXXXX +161%  
1-Year High: XXX on 2025-09-03  
1-Year Low: XX on 2025-01-27  

Mentions by network (24h):
News: XX
Reddit: X
X: XXX
YouTube: XX

  
  
### Creators: XX (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/$ions/time-series/contributors_active.tsv)  
XX unique social accounts have posts mentioning Ionis Pharmaceuticals, Inc. Common Stock (IONS) in the last XX hours which is down XX% from XX in the previous XX hours
Daily Average: XX  
X Week: XXX -XX%  
X Month: XXX +35%  
X Months: XXXXX +152%  
X Year: XXXXX +182%  
1-Year High: XXX on 2025-06-28  
1-Year Low: XX on 2025-01-28  

The most influential creators that mention Ionis Pharmaceuticals, Inc. Common Stock in the last XX hours

| Creator                                              | Rank | Followers | Posts | Engagements |
| -------                                              | ---- | --------- | ----- | ----------- |
| [@BuyTheUgly](/creator/twitter/BuyTheUgly)           | X    | XX        | X     | XXX         |
| [@ParadiseTraderr](/creator/twitter/ParadiseTraderr) | X    | XXX       | X     | XXX         |
| [@Fredbenz0](/creator/twitter/Fredbenz0)             | X    | XXXXX     | X     | XXX         |
| [@TheOptionsBull2](/creator/twitter/TheOptionsBull2) | X    | XXX       | X     | XXX         |
| [@ice_blockchain](/creator/twitter/ice_blockchain)   | X    | XXXXXXXXX | X     | XXX         |
| [@RNAiAnalyst](/creator/twitter/RNAiAnalyst)         | X    | XXXXXX    | X     | XXX         |
| [@Biobeats99](/creator/twitter/Biobeats99)           | X    | XXX       | X     | XX          |
| [@StockMKTNewz](/creator/twitter/StockMKTNewz)       | X    | XXXXXXX   | X     | XX          |
| [@ArtsStocks](/creator/twitter/ArtsStocks)           | X    | XXX       | X     | XX          |
| [@seedytx19](/creator/twitter/seedytx19)             | XX   | XXXXX     | X     | XX          |

[View More](/list/creators/$ions/100)
  
  
### Sentiment: XX%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/$ions/time-series/sentiment.tsv)  
Current Value: XX%  
Daily Average: XX%  
X Week: XXX% +33%  
X Month: XXX% +31%  
X Months: XXX% +24%  
X Year: XXX% +38%  
1-Year High: XXX% on 2025-01-30  
1-Year Low: XX% on 2025-01-26  

Most Supportive Themes:
- Analyst Upgrades and Price Targets: (30%) Analysts are increasing their confidence and price targets for Ionis Pharmaceuticals.
- Positive Phase X Trial Results: (25%) Promising results from Phase X trials for olezarsen and zilganersen are leading to planned regulatory filings.
- Strong Q3 Earnings Report: (20%) Ionis Pharmaceuticals reported strong Q3 earnings, exceeding expectations and raising its full-year revenue outlook.
- 52-Week High Stock Price: (15%) The stock has reached a 52-week high, reflecting positive market sentiment and strong community engagement.
  
Most Critical Themes:
- FDA Holds on Drug Testing: (5%) The FDA has placed a hold on certain drug testing, which could potentially delay study readouts and impact investor sentiment.
  
  
  
### Social Dominance: XXXXX%
![Social Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:social_dominance/iv:1d.svg)  
[Social Dominance 24-Hour Time-Series Raw Data](/topic/$ions/time-series/social_dominance.tsv)  
Current Value: XXXXX%  
Daily Average: XXXXX%  
X Week: XXXXXX% +0.0006999999999999992%  
X Month: XXXXX% +0.046%  
X Months: XXXXX% +0.043%  
X Year: XXXXX% +0.036%  
1-Year High: XXXXX% on 2024-12-22  
1-Year Low: XXXXXX% on 2025-10-24  
  
  
### Market Dominance: XXXXX%
![Market Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:market_dominance/iv:1d.svg)  
[Market Dominance 24-Hour Time-Series Raw Data](/topic/$ions/time-series/market_dominance.tsv)  
Current Value: XXXXX%  
Daily Average: X%  
1-Year High: XXXXX% on 2025-12-02  
1-Year Low: XXXXXXX% on 2025-04-02  
  
  
### Market Cap: $XXXXXXXXXXXXXX
![Market Cap Line Chart](https://lunarcrush.com/gi/w:600/t:$ions/c:line/m:market_cap/iv:1d.svg)  
[Market Cap 24-Hour Time-Series Raw Data](/topic/$ions/time-series/market_cap.tsv)  
Current Value: $XXXXXXXXXXXXXX  
Daily Average: $XXXXXXXXXXXXX  
X Week: $XXXXXXXXXXXXXX -$3%  
X Month: $XXXXXXXXXXXXXX +$7.20%  
X Months: $XXXXXXXXXXXXXX +$125%  
X Year: $XXXXXXXXXXXXXX +$110%  
1-Year High: $XXXXXXXXXXXXXX on 2025-11-28  
1-Year Low: $XXXXXXXXXXXXX on 2025-04-08  

### Top Ionis Pharmaceuticals, Inc. Common Stock News
Top news links shared on social in the last XX hours  

*Showing a maximum of X news posts for non-authenticated requests. Use your API key in requests for full results.*  

"Metagenomi to Present Preclinical Data Supporting New Collaboration Target of APOC3 with Ionis Pharmaceuticals at Upcoming Nature Conference"  
[News Link](https://finance.yahoo.com/news/metagenomi-present-preclinical-data-supporting-120000890.html) [@YahooFinance](/creator/x/YahooFinance) 2025-12-01T13:37Z 228.6M followers, 3013 engagements



### Top Ionis Pharmaceuticals, Inc. Common Stock Social Posts
Top posts by engagements in the last XX hours

*Showing only X posts for non-authenticated requests. Use your API key in requests for full results.*

"Highly impressed with this setup $CGEM $STOK $TVTX $CLDX $SNDX $VYGR $AMTI $EWTX $OYST $VIR $SMMT $KYMR $ADCT $HARP $INSM $IMAB $XBIT $AXSM $PASG $ZGNX $IONS $ETNB $OTLK $RYTM $RGNX $NGM $UTHR $IMVT $REGN $ADAP $NBIX $PDSB $IGMS"  
[X Link](https://x.com/BuyTheUgly/status/1998485125680738411) [@BuyTheUgly](/creator/x/BuyTheUgly) 2025-12-09T20:09Z XX followers, XXX engagements


"Stock market watchlist #1 $RUBI #2 $ASST#3 $FGL #4 $RELI #5 $VNRX #6 $IVP #7 $CHR #8 $BNED#9 $CMND $SMMT $CPRX $CRMD $HUMA $MREO $TCRX $SCPL $VTGN $SCPH $ADMA $BMRN $FOLD $ICPT $IONS $INTL $SGMO $CLDX $INO $KRTX $ONTX $ARVN $MGNX $EIGR $SPR $NVAX $SRPT $ABEO $ANVS $BCEL"  
[X Link](https://x.com/ParadiseTraderr/status/1998484362669768941) [@ParadiseTraderr](/creator/x/ParadiseTraderr) 2025-12-09T20:06Z XXX followers, XXX engagements


"9/10 Thats why $ARWR is totally miscomped. The right peers are $ALNY and $IONS platforms that repeatedly generate drugs and earn higher multiples"  
[X Link](https://x.com/BioBoyScout/status/1998463023363600721) [@BioBoyScout](/creator/x/BioBoyScout) 2025-12-09T18:41Z 4012 followers, XXX engagements


"Top losing stocks last hour $TMUS $MRK $META $LLY $ABBV $JNJ $HD $AZN $NFLX $GE $FERG $BIDU $XPEV $ASTS $SMMT $IONS $ORLY $XP $WELL $DEO"  
[X Link](https://x.com/KathleenHGraham/status/1998430081677447200) [@KathleenHGraham](/creator/x/KathleenHGraham) 2025-12-09T16:30Z XXX followers, XX engagements

[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

Ionis Pharmaceuticals, Inc. Common Stock (IONS)

Metagenomi will present preclinical data supporting a new collaboration target of APOC3 with Ionis Pharmaceuticals at an upcoming Nature Conference. This news follows recent analyst upgrades and positive trial results.

About Ionis Pharmaceuticals, Inc. Common Stock

Ionis Pharmaceuticals, Inc. is a biotechnology company focused on developing RNA-targeted therapeutics.
Ionis Pharmaceuticals, Inc. Common Stock uses the ticker $IONS for trading. Listed in the Stocks category within the Healthcare sectors.

Insights

Ionis Pharmaceuticals, Inc. Common Stock (IONS) social dominance hit XXXXXX which is XXX% higher than it's daily average.
Ionis Pharmaceuticals, Inc. Common Stock (IONS) trading volume is up XXXXXX% from the previous X months.
Ionis Pharmaceuticals, Inc. Common Stock (IONS) sentiment is up XXXXX% from the previous year.

Price: $XXXXX

Price 24-Hour Time-Series Raw Data
The stock price is experiencing a significant surge, hitting a 52-week high, driven by positive analyst sentiment, strong Q3 earnings, and promising Phase X trial results for key drugs. This positive momentum is outweighing a minor FDA hold, and social media sentiment is overwhelmingly positive.

24-Hour: -XXXX% 7-Day: -XXXX% 30-Day: XXXX%

1-Year High: $XXXXX on 2025-11-28
1-Year Low: $XXXXX on 2025-04-08

AltRank: XXX

AltRank Line Chart
AltRank 24-Hour Time-Series Raw Data
Ionis Pharmaceuticals, Inc. Common Stock (IONS) is currently AltRank #634 based on combined combined social and market metrics Daily Average: XXX
X Week: XXX -XXX
X Month: XXX -XXX
X Months: XXX -XXX
X Year: XXX +80
1-Year High: XXXXX on 2025-08-06
1-Year Low: XX on 2025-01-11

Galaxy Score: XXXXX

Galaxy Score Line Chart
Galaxy Score 24-Hour Time-Series Raw Data
Current Value: XXXXX
Daily Average: XX
X Week: XX no change
X Month: XX +2
X Months: XX -X
X Year: XX -XX
1-Year High: XX on 2025-04-07
1-Year Low: XX on 2025-07-08

Engagements: XXXXX (24h)

Engagements Line Chart
Engagements 24-Hour Time-Series Raw Data
Current Value: XXXXX
Daily Average: XXXXXX
X Week: XXXXXX -XX%
X Month: XXXXXXX +25%
X Months: XXXXXXXXX +41%
X Year: XXXXXXXXX +123%
1-Year High: XXXXXXX on 2025-02-19
1-Year Low: XXXXX on 2025-03-09

Engagements by network (24h): News: XXX Reddit: XX X: XXXXX YouTube: XXXXX

Mentions: XX (24h)

Mentions Line Chart
Mentions 24-Hour Time-Series Raw Data
Current Value: XX
Daily Average: XXX
X Week: XXX -XX%
X Month: XXXXX +57%
X Months: XXXXX +81%
X Year: XXXXX +161%
1-Year High: XXX on 2025-09-03
1-Year Low: XX on 2025-01-27

Mentions by network (24h): News: XX Reddit: X X: XXX YouTube: XX

Creators: XX (24h)

Creators Line Chart
Creators 24-Hour Time-Series Raw Data
XX unique social accounts have posts mentioning Ionis Pharmaceuticals, Inc. Common Stock (IONS) in the last XX hours which is down XX% from XX in the previous XX hours Daily Average: XX
X Week: XXX -XX%
X Month: XXX +35%
X Months: XXXXX +152%
X Year: XXXXX +182%
1-Year High: XXX on 2025-06-28
1-Year Low: XX on 2025-01-28

The most influential creators that mention Ionis Pharmaceuticals, Inc. Common Stock in the last XX hours

Creator	Rank	Followers	Posts	Engagements
@BuyTheUgly	X	XX	X	XXX
@ParadiseTraderr	X	XXX	X	XXX
@Fredbenz0	X	XXXXX	X	XXX
@TheOptionsBull2	X	XXX	X	XXX
@ice_blockchain	X	XXXXXXXXX	X	XXX
@RNAiAnalyst	X	XXXXXX	X	XXX
@Biobeats99	X	XXX	X	XX
@StockMKTNewz	X	XXXXXXX	X	XX
@ArtsStocks	X	XXX	X	XX
@seedytx19	XX	XXXXX	X	XX

Sentiment: XX%

Sentiment Line Chart
Sentiment 24-Hour Time-Series Raw Data
Current Value: XX%
Daily Average: XX%
X Week: XXX% +33%
X Month: XXX% +31%
X Months: XXX% +24%
X Year: XXX% +38%
1-Year High: XXX% on 2025-01-30
1-Year Low: XX% on 2025-01-26

Most Supportive Themes:

Analyst Upgrades and Price Targets: (30%) Analysts are increasing their confidence and price targets for Ionis Pharmaceuticals.
Positive Phase X Trial Results: (25%) Promising results from Phase X trials for olezarsen and zilganersen are leading to planned regulatory filings.
Strong Q3 Earnings Report: (20%) Ionis Pharmaceuticals reported strong Q3 earnings, exceeding expectations and raising its full-year revenue outlook.
52-Week High Stock Price: (15%) The stock has reached a 52-week high, reflecting positive market sentiment and strong community engagement.

Most Critical Themes:

FDA Holds on Drug Testing: (5%) The FDA has placed a hold on certain drug testing, which could potentially delay study readouts and impact investor sentiment.

Social Dominance: XXXXX%

Social Dominance Line Chart
Social Dominance 24-Hour Time-Series Raw Data
Current Value: XXXXX%
Daily Average: XXXXX%
X Week: XXXXXX% +0.0006999999999999992%
X Month: XXXXX% +0.046%
X Months: XXXXX% +0.043%
X Year: XXXXX% +0.036%
1-Year High: XXXXX% on 2024-12-22
1-Year Low: XXXXXX% on 2025-10-24

Market Dominance: XXXXX%

Market Dominance Line Chart
Market Dominance 24-Hour Time-Series Raw Data
Current Value: XXXXX%
Daily Average: X%
1-Year High: XXXXX% on 2025-12-02
1-Year Low: XXXXXXX% on 2025-04-02

Market Cap: $XXXXXXXXXXXXXX

Market Cap Line Chart
Market Cap 24-Hour Time-Series Raw Data
Current Value: $XXXXXXXXXXXXXX
Daily Average: $XXXXXXXXXXXXX
X Week: $XXXXXXXXXXXXXX -$3%
X Month: $XXXXXXXXXXXXXX +$7.20%
X Months: $XXXXXXXXXXXXXX +$125%
X Year: $XXXXXXXXXXXXXX +$110%
1-Year High: $XXXXXXXXXXXXXX on 2025-11-28
1-Year Low: $XXXXXXXXXXXXX on 2025-04-08

Top Ionis Pharmaceuticals, Inc. Common Stock News

Top news links shared on social in the last XX hours

Showing a maximum of X news posts for non-authenticated requests. Use your API key in requests for full results.

"Metagenomi to Present Preclinical Data Supporting New Collaboration Target of APOC3 with Ionis Pharmaceuticals at Upcoming Nature Conference"
News Link @YahooFinance 2025-12-01T13:37Z 228.6M followers, 3013 engagements

Top Ionis Pharmaceuticals, Inc. Common Stock Social Posts

Top posts by engagements in the last XX hours

Showing only X posts for non-authenticated requests. Use your API key in requests for full results.

"Highly impressed with this setup $CGEM $STOK $TVTX $CLDX $SNDX $VYGR $AMTI $EWTX $OYST $VIR $SMMT $KYMR $ADCT $HARP $INSM $IMAB $XBIT $AXSM $PASG $ZGNX $IONS $ETNB $OTLK $RYTM $RGNX $NGM $UTHR $IMVT $REGN $ADAP $NBIX $PDSB $IGMS"
X Link @BuyTheUgly 2025-12-09T20:09Z XX followers, XXX engagements

"Stock market watchlist #1 $RUBI #2 $ASST#3 $FGL #4 $RELI #5 $VNRX #6 $IVP #7 $CHR #8 $BNED#9 $CMND $SMMT $CPRX $CRMD $HUMA $MREO $TCRX $SCPL $VTGN $SCPH $ADMA $BMRN $FOLD $ICPT $IONS $INTL $SGMO $CLDX $INO $KRTX $ONTX $ARVN $MGNX $EIGR $SPR $NVAX $SRPT $ABEO $ANVS $BCEL"
X Link @ParadiseTraderr 2025-12-09T20:06Z XXX followers, XXX engagements

"9/10 Thats why $ARWR is totally miscomped. The right peers are $ALNY and $IONS platforms that repeatedly generate drugs and earn higher multiples"
X Link @BioBoyScout 2025-12-09T18:41Z 4012 followers, XXX engagements

"Top losing stocks last hour $TMUS $MRK $META $LLY $ABBV $JNJ $HD $AZN $NFLX $GE $FERG $BIDU $XPEV $ASTS $SMMT $IONS $ORLY $XP $WELL $DEO"
X Link @KathleenHGraham 2025-12-09T16:30Z XXX followers, XX engagements