[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

![mtheory11bio Avatar](https://lunarcrush.com/gi/w:24/cr:twitter::1555606459.png) Chris Carper [@mtheory11bio](/creator/twitter/mtheory11bio) on x 4891 followers
Created: 2025-07-22 11:45:20 UTC

I get that investors are nervous about single arm trials being adequate for approval after the $REPL CRL, but that’s why $QURE agreed with the FDA on a SAP using a matched external control.

If the bar for approval has been lifted, $QURE is still above it in my opinion.


XXXXX engagements

![Engagements Line Chart](https://lunarcrush.com/gi/w:600/p:tweet::1947623998184989170/c:line.svg)

**Related Topics**
[sap](/topic/sap)
[$qure](/topic/$qure)
[$repl](/topic/$repl)

[Post Link](https://x.com/mtheory11bio/status/1947623998184989170)