[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]  Andrew Caravello, DO [@andrewcaravello](/creator/twitter/andrewcaravello) on x 1073 followers Created: 2025-07-18 14:53:55 UTC $NWBO 🧬 DCVax for Narcissism? A Thought Experiment on Immune Calibration and Self-Obsession Narcissism is not classified as an immune disorder, but maybe it should be. At its core, narcissism is the pathological over-recognition of the self. It is a psychological state where the internal signal of “me” is amplified beyond all proportion, often at the expense of empathy, regulation, or external truth. Now consider what dendritic cells do. Dendritic cells are immune instructors. Their job is to distinguish self from non-self, and to train the immune system to respond appropriately. They maintain tolerance to normal tissue while activating attack against true threats. When dendritic cells are immature or dysregulated, the result is either • under-response to danger (as in cancer), or • over-response to the self (as in autoimmunity) And in narcissism, the response to self is not just preserved, it is glorified. So here is the hypothesis. What if narcissism is a cognitive mirror of immune dysfunction, where the antigen presentation is hijacked by identity reinforcement? What if the system is trained to elevate “me” as the only acceptable signal, and to suppress all foreign input as irrelevant? That is where DCVax becomes interesting. DCVax does not simply provoke an immune response. It re-educates it. By pulsing autologous dendritic cells with tumor antigens, then maturing them ex vivo using tightly defined cytokine signals, DCVax retrains the immune system to stop tolerating what it once ignored. Now imagine this applied to narcissism. A therapeutic reset that breaks the loop of pathological self-recognition, and reopens the cognitive immune window to external signals. DCVax as cognitive immunotherapy. Self-awareness as antigen. Empathy as immune rebound. Would it work? Not in any literal psychiatric setting. But as a metaphor, it lands. Sometimes the most dangerous tumors are not physical. They are the ones that convince the host they are the whole body. And those, too, may need re-education. XXXXX engagements  **Related Topics** [$nwbo](/topic/$nwbo) [Post Link](https://x.com/andrewcaravello/status/1946221903770943870)
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
Andrew Caravello, DO @andrewcaravello on x 1073 followers
Created: 2025-07-18 14:53:55 UTC
$NWBO 🧬 DCVax for Narcissism? A Thought Experiment on Immune Calibration and Self-Obsession
Narcissism is not classified as an immune disorder, but maybe it should be.
At its core, narcissism is the pathological over-recognition of the self. It is a psychological state where the internal signal of “me” is amplified beyond all proportion, often at the expense of empathy, regulation, or external truth.
Now consider what dendritic cells do.
Dendritic cells are immune instructors. Their job is to distinguish self from non-self, and to train the immune system to respond appropriately. They maintain tolerance to normal tissue while activating attack against true threats.
When dendritic cells are immature or dysregulated, the result is either • under-response to danger (as in cancer), or • over-response to the self (as in autoimmunity)
And in narcissism, the response to self is not just preserved, it is glorified.
So here is the hypothesis. What if narcissism is a cognitive mirror of immune dysfunction, where the antigen presentation is hijacked by identity reinforcement? What if the system is trained to elevate “me” as the only acceptable signal, and to suppress all foreign input as irrelevant?
That is where DCVax becomes interesting.
DCVax does not simply provoke an immune response. It re-educates it. By pulsing autologous dendritic cells with tumor antigens, then maturing them ex vivo using tightly defined cytokine signals, DCVax retrains the immune system to stop tolerating what it once ignored.
Now imagine this applied to narcissism. A therapeutic reset that breaks the loop of pathological self-recognition, and reopens the cognitive immune window to external signals.
DCVax as cognitive immunotherapy. Self-awareness as antigen. Empathy as immune rebound.
Would it work? Not in any literal psychiatric setting. But as a metaphor, it lands.
Sometimes the most dangerous tumors are not physical. They are the ones that convince the host they are the whole body. And those, too, may need re-education.
XXXXX engagements
Related Topics $nwbo