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# ![@PersimmonTI Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::4496252499.png) @PersimmonTI Persimmon Tree Investments

Persimmon Tree Investments posts on X about $xbi, $akro, $mrus, $slno the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXXX engagements in the last XX hours.

### Engagements: XXXXXX [#](/creator/twitter::4496252499/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::4496252499/c:line/m:interactions.svg)

- X Week XXXXXXX -XX%
- X Month XXXXXXX +81%
- X Months XXXXXXXXX +91%
- X Year XXXXXXXXX +240%

### Mentions: XX [#](/creator/twitter::4496252499/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::4496252499/c:line/m:posts_active.svg)

- X Week XXX -XXXX%
- X Month XXX +14%
- X Months XXX +73%
- X Year XXXXX +412%

### Followers: XXXXXX [#](/creator/twitter::4496252499/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::4496252499/c:line/m:followers.svg)

- X Week XXXXXX +0.57%
- X Month XXXXXX +3.40%
- X Months XXXXXX +13%
- X Year XXXXXX +24%

### CreatorRank: XXXXXXX [#](/creator/twitter::4496252499/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::4496252499/c:line/m:influencer_rank.svg)

### Social Influence [#](/creator/twitter::4496252499/influence)
---

**Social category influence**
[stocks](/list/stocks)  XXXX% [finance](/list/finance)  XXXX% [currencies](/list/currencies)  XXXX% [technology brands](/list/technology-brands)  XXXX% [countries](/list/countries)  XXXX% [social networks](/list/social-networks)  XXXX% [cryptocurrencies](/list/cryptocurrencies)  XXXX% [celebrities](/list/celebrities)  XXXX% [travel destinations](/list/travel-destinations)  XXXX%

**Social topic influence**
[$xbi](/topic/$xbi) #4, [$akro](/topic/$akro) #1, [$mrus](/topic/$mrus) #5, [$slno](/topic/$slno) #3, [$mtsr](/topic/$mtsr) #2, [$srrk](/topic/$srrk) 1.63%, [$etnb](/topic/$etnb) #3, [$pfe](/topic/$pfe) #90, [$nktr](/topic/$nktr) #28, [$mrk](/topic/$mrk) #59

**Top accounts mentioned or mentioned by**
[@natrevdrugdisc](/creator/undefined) [@biopharmiq](/creator/undefined) [@nature](/creator/undefined) [@amaymd](/creator/undefined) [@bowtiedbiotech](/creator/undefined) [@pcm_bio](/creator/undefined) [@adamfeuerstein](/creator/undefined) [@inshatters1](/creator/undefined) [@fiercepharma](/creator/undefined) [@duedoctor](/creator/undefined) [@fakepharmabro](/creator/undefined) [@cloisterres](/creator/undefined) [@plainyogurt21](/creator/undefined) [@joserestonva](/creator/undefined) [@shortsellerst](/creator/undefined) [@jacobplieth](/creator/undefined) [@naturebiotech](/creator/undefined) [@billackman](/creator/undefined) [@jfais20](/creator/undefined) [@scartissue123](/creator/undefined)

**Top assets mentioned**
[Bitcoin Incognito (XBI)](/topic/$xbi) [Akropolis (AKRO)](/topic/$akro) [Merus N.V. Common Shares (MRUS)](/topic/$mrus) [Soleno Therapeutics, Inc. Common Stock (SLNO)](/topic/$slno) [Metsera, Inc. Common Stock (MTSR)](/topic/$mtsr) [Scholar Rock Holding Corporation Common Stock (SRRK)](/topic/$srrk) [Pfizer, Inc. (PFE)](/topic/$pfe) [Merck & Co., Inc. (MRK)](/topic/$mrk) [Eli Lilly and Company (LLY)](/topic/$lly) [Novo-Nordisk (NVO)](/topic/$nvo) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [NewAmsterdam Pharma Company N.V. Ordinary Shares (NAMS)](/topic/$nams) [Amgen, Inc. (AMGN)](/topic/$amgn) [Cytokinetics Inc. (CYTK)](/topic/$cytk) [Gilead Sciences, Inc. (GILD)](/topic/$gild) [Protagonist Therapeutics, Inc (PTGX)](/topic/$ptgx) [IDEAYA Biosciences, Inc. Common Stock (IDYA)](/topic/$idya) [Kymera Therapeutics, Inc. Common Stock (KYMR)](/topic/$kymr) [Madrigal Pharmaceuticals, Inc. Common Stock (MDGL)](/topic/$mdgl) [GSK plc (GSK)](/topic/$gsk) [uniQure N.V. (QURE)](/topic/$qure) [Summit Therapeutics Inc. Common Stock (SMMT)](/topic/$smmt) [Johnson & Johnson (JNJ)](/topic/$jnj) [Janux Therapeutics, Inc. Common Stock (JANX)](/topic/$janx) [Novartis AG (NVS)](/topic/$nvs) [Morgan Stanley (MS)](/topic/morgan-stanley) [MEI Pharma, Inc. (MEIP)](/topic/$meip) [MoonLake Immunotherapeutics Class A Ordinary Shares (MLTX)](/topic/$mltx) [ROGin AI (ROG)](/topic/$rog) [Synthetify (SNY)](/topic/$sny) [BridgeBio Pharma, Inc. Common Stock (BBIO)](/topic/$bbio) [Apellis Pharmaceuticals, Inc. Common Stock (APLS)](/topic/$apls) [Disc Medicine, Inc. Common Stock (IRON)](/topic/$iron)
### Top Social Posts [#](/creator/twitter::4496252499/posts)
---
Top posts by engagements in the last XX hours

"$JANX $10.6mm sell in the AM today a big seller now out of the way for shares to continue rising But mgmt leaves a lot to be desired re: transparency & communication "  
[X Link](https://x.com/PersimmonTI/status/1978603530085699683) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-15T23:26Z 10.3K followers, 1954 engagements


"$SLNO Lets do this Centerview: Maybe $NVS or $BMY"  
[X Link](https://x.com/PersimmonTI/status/1978890343211786386) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T18:26Z 10.3K followers, 4968 engagements


"$ABVX XX% of the portfolio in total across multiple accounts"  
[X Link](https://x.com/PersimmonTI/status/1980004385879945503) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-19T20:13Z 10.3K followers, 9196 engagements


"$AMGN Tarlatamab remarkable $MRK x $HARP $IDYA $ZLAB It was a busy ASCO in its own way this year but havent seen much on Twitter about the remarkable $AMGN late-breaker for its DLL3-targeting bispecific TCE tarlatamab in second line SCLC. @DrSamuelBHume with a nice callout of the data retweeted below. SCLC a tough indication and here we have a T Cell engager going up head to head with physicians choice chemotherapy in the Second line and showing a greater than X month improvement in mOS Remarkable. But even more remarkable to me is the fact that in the DeLLphi-304 Phase X trial tarlatamab"  
[X Link](https://x.com/PersimmonTI/status/1931802328526647771) [@PersimmonTI](/creator/x/PersimmonTI) 2025-06-08T19:55Z 10.3K followers, 6444 engagements


"$MRK $xbi Merck CEO Rob Davis at Morgan Stanley on business development strategy He starts with the usual first in class best in class $X to $15B mantra looking for a few more in the $VRNA-size wheelhouse but then notes willingness to think bigger if those dont materialize: The $X to $XX billion that we've been following continues to be our preferred area but we remain open to others if the parameters of value science and all come together in the right way. $INSM would seem to be the obvious choice if $MRK is thinking big "  
[X Link](https://x.com/PersimmonTI/status/1967233417944113197) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-14T14:26Z 10.3K followers, 8052 engagements


"$XBI Clinical trials of synthetic lethal therapies courtesy @NatRevDrugDisc $IDYA $TNGX $RAPT $APRE $BMY "  
[X Link](https://x.com/PersimmonTI/status/1967259100967776518) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-14T16:08Z 10.3K followers, 3835 engagements


"$MEIP Very bullish $xbi"  
[X Link](https://x.com/PersimmonTI/status/1967273032663343537) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-14T17:03Z 10.3K followers, 2749 engagements


"$SRRK Apitegromab issued a CRL:"  
[X Link](https://x.com/PersimmonTI/status/1970443875648184711) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-23T11:03Z 10.3K followers, 2570 engagements


"$SRRK So. Short the launch but buy the CRL dip. Works for me"  
[X Link](https://x.com/PersimmonTI/status/1970560912152006836) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-23T18:48Z 10.3K followers, 3707 engagements


"$VYNE $MLTX $ATYR Each dropping highly anticipated data readouts without a prerelease PR. And $MLTX opting for highly popular 12pm on Sunday time slot to boot:"  
[X Link](https://x.com/PersimmonTI/status/1972490626311868913) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T02:36Z 10.2K followers, 3743 engagements


"$XBI $ETNB $MTSR $MRUS All precommercial"  
[X Link](https://x.com/PersimmonTI/status/1972617003413422324) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T10:58Z 10.2K followers, 2864 engagements


"$LRMR Anaphylaxis observed dosing adjusted BLA filing still targeted Q2 2026. "  
[X Link](https://x.com/PersimmonTI/status/1972641508307484877) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T12:36Z 10.2K followers, 7688 engagements


"$LRMR I never got a good feel for $LRMR mgmt and this PR language does nothing to change that: Anaphylaxis has been reported in X participants in the OL study with most events occurring on the initial day of administration and all occurring within the first X weeks of dosing; excluding these events long term dosing of nomlabofusp was generally well tolerated Editor: Aside from ANAPHYLAXIS the most severe allergic reaction known to man which can be sudden severe and fatal if not promptly treated by the immediate administration of epinephrine which occurred in SEVEN participants the long term"  
[X Link](https://x.com/PersimmonTI/status/1972817222256017760) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-30T00:14Z 10.2K followers, 4400 engagements


"$OVID Positive results with a side of wall-crossed financing per the usual Probably why the data PR took a while. "  
[X Link](https://x.com/PersimmonTI/status/1974070596062310722) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-03T11:14Z 10.2K followers, 14.5K engagements


"$XBI M&A Below the top XX biopharma M&A in 2025 ranked by total deal value As of 7/29/25 courtesy @nature biopharma dealmakers Of course doesnt include the recent flurry of activity: 9/18/25 $ETNB x $ROG $2.4B upfront $3.5B total deal value w/ CVRs. 9/22/25 $MTSR x $PFE $4.9B upfront $7.2B total deal value w/ CVRs. 9/29/25 $MRUS x $GMAB $8B. As many had anticipated/hoped looks like deal activity is building toward year end as macro clarity improves: "  
[X Link](https://x.com/PersimmonTI/status/1974822368871682556) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-05T13:01Z 10.3K followers, 6969 engagements


"$SRRK The interesting trading in Scholar Rock continues Friday afternoon volume and price action picks up:"  
[X Link](https://x.com/PersimmonTI/status/1974838315317674487) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-05T14:05Z 10.3K followers, 1664 engagements


"$XBI going to $XBI and some things never change $OVID delayed data to finish up wall-crossed financing. $ACET LN data PRed near simultaneous with wall-crossed registered direct offering. $JBIO new clinical candidate with a private placement"  
[X Link](https://x.com/PersimmonTI/status/1975527326575435995) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-07T11:43Z 10.2K followers, 6126 engagements


"$AKRO Deep Track Capital LP with a 1357000 share open market add to their $AKRO position making it: - their second largest holding at XXX% of portfolio - XXX% of $AKRO outstanding share count And take a look at Deep Tracks top ten"  
[X Link](https://x.com/PersimmonTI/status/1975670665052365199) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-07T21:12Z 10.3K followers, 9206 engagements


"$NKTR Completely orthogonal but This is what can happen at jury trial and if this can happen over talcum powder Well what do we think a jury will make of $LLY obfuscation I happen to think they would want to make: an example"  
[X Link](https://x.com/PersimmonTI/status/1975717534839038404) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-08T00:19Z 10.3K followers, 11.2K engagements


"$SNY AlphaMedixTM (212Pb-DOTAMTATE) achieved all primary efficacy endpoints in phase X study demonstrating clinically meaningful benefits in patients with gastroenteropancreatic neuroendocrine tumors. But I dont see no data Guess well have to wait for ESMO:"  
[X Link](https://x.com/PersimmonTI/status/1975877249858470091) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-08T10:53Z 10.3K followers, 1642 engagements


"$IMAB Perhaps market waking up to the fact that givastomig could change the SOC in Claudin18.2 positive gastric cancer One of my largest positions"  
[X Link](https://x.com/PersimmonTI/status/1975922275745411325) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-08T13:52Z 10.3K followers, 6048 engagements


"$XBI Hello my fellow generalists. Can I interest you in an investment opportunity of which I only recently learned"  
[X Link](https://x.com/PersimmonTI/status/1976035110802878659) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-08T21:20Z 10.3K followers, 3740 engagements


"$KYMR I liked the setup going into XXX healthy volunteer readout both in valuation and Mainolfis exuberant tells in investor conferences about what the data would likely reveal. I dont like the setup going into XXX phase 1b in AD for the same reasons in reverse"  
[X Link](https://x.com/PersimmonTI/status/1976087479636930958) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T00:49Z 10.3K followers, 3849 engagements


"$AKRO Good timing by Deep Track to up their $AKRO stake They were/are also large holders of $ETNB"  
[X Link](https://x.com/PersimmonTI/status/1976233774003503218) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T10:30Z 10.3K followers, 5203 engagements


"$SRRK There's just something odd about all of this. Radio silence from the C Suite for months a huge open market insider buy by director recently (likely dashing hopes for any imminent buyout it must be said) and yet. The share price ebullience continues unchecked. Something odd"  
[X Link](https://x.com/PersimmonTI/status/1976291992259735738) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T14:21Z 10.3K followers, 4578 engagements


"$XBI There are shorts and then there are shorts. A priori short authors who point out the perceived flaws of a biological and/or methodological approach are valuable imho. Some of my favorite examples: @TCellEngager @Buffalo51766917 @anthonystaj"  
[X Link](https://x.com/PersimmonTI/status/1977371422784643273) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T13:50Z 10.3K followers, 5979 engagements


"$IMAB We doing short talks now Okay well I guess Im here for it:"  
[X Link](https://x.com/PersimmonTI/status/1978058777094983742) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T11:22Z 10.3K followers, 1648 engagements


"$XBI Looking back at some recently prior takes got some right: $AKRO $MRUS some wrong: $SRRK and some. still cooking I would say: $GPCR $NKTR $BBIO"  
[X Link](https://x.com/PersimmonTI/status/1978224257902522714) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T22:19Z 10.3K followers, 4252 engagements


"@nociFTW Maybe they should merge with $GLPG"  
[X Link](https://x.com/PersimmonTI/status/1978607904086192626) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-15T23:44Z 10.3K followers, XXX engagements


"@DueDoctor what is $CYTK and what do they do"  
[X Link](https://x.com/PersimmonTI/status/1978627519751282879) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T01:02Z 10.2K followers, 1233 engagements


"$XBI We could really use a buyout"  
[X Link](https://x.com/PersimmonTI/status/1978888192951513163) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T18:18Z 10.3K followers, 7467 engagements


"$XBI Select FDA New Drug Approvals in Q3 2025 courtesy @NatRevDrugDisc"  
[X Link](https://x.com/PersimmonTI/status/1979528076829593760) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-18T12:40Z 10.3K followers, 3217 engagements


"$XBI A very nice nuanced @FiercePharma piece on the state of MASH therapeutics: $MDGL $NVO $GSK $RHHBY $AKRO $ETNB"  
[X Link](https://x.com/PersimmonTI/status/1979596210710159653) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-18T17:11Z 10.3K followers, 1802 engagements


"$NKTR For the record I think that $LLY acquiring $NKTR outright at this juncture is highly unlikely. But one need go back only to this past August to find precedent of bitter legal battle ending in an acquisition (plus a settlement) See $BNTX more than calling a truce with longtime litigant $CVAC but actually purchasing $CVAC outright. It was an IP fight and $BNTX did the risk-based analysis and decided were not likely to beat $CVAC so lets just buy their IP by buying the whole company And call it a day Again not likely with $LLY x $NKTR. But who knows 🤷🏻♀"  
[X Link](https://x.com/PersimmonTI/status/1979606944492007470) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-18T17:54Z 10.3K followers, 9360 engagements


"$XBI Selected Therapies in Development for Obesity Courtesy the incomparable @NatRevDrugDisc (Editor: and pre $MTSR buyout by $PFE) "  
[X Link](https://x.com/PersimmonTI/status/1979900758955868313) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-19T13:21Z 10.3K followers, 1946 engagements


"$QURE Think where the real battleground may lie is in pricing"  
[X Link](https://x.com/PersimmonTI/status/1980089474068762803) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-20T01:51Z 10.3K followers, 5373 engagements


"$REPL wow just wow $xbi"  
[X Link](https://x.com/PersimmonTI/status/1980229088917987667) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-20T11:06Z 10.3K followers, 5905 engagements


"$MRUS Im pretty sure that $GMAB has seen the early Peto CRC dose escalation data And my guess is that those data are good"  
[X Link](https://x.com/PersimmonTI/status/1972615550145798364) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T10:52Z 10.3K followers, 6869 engagements


"$MRUS Small N and more data to come at plenary oral later this month but Peto in mCRC (efficacy evaluable): 1L combo 3/3 ORR XXX% 2L combo 4/8 ORR XX% 3L mono one PR in this late line "  
[X Link](https://x.com/PersimmonTI/status/1978065712900890951) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T11:49Z 10.3K followers, 4157 engagements


"$NKTR X. The court is concerned that a jury trial may not be sustainable in current circumstances X. With pre-trial conference vacated On its face these two statements could be perceived as at odds. In order to sustain a jury trial it would make more sense to expedite/stay on track with a pre-trial conference But to square the circle seems to point to both sides $NKTR and $LLY having shown court some indication of wanting to settle before trial but there being an impasse at present with regard to dollar value Likely this dry PACER summary was more lively in person with Judge saying something"  
[X Link](https://x.com/PersimmonTI/status/1978229433153560993) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T22:40Z 10.3K followers, 12K engagements


"$CCCC And we have another private placement. So core and surprisingly at the right price"  
[X Link](https://x.com/PersimmonTI/status/1978782552606286041) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T11:18Z 10.3K followers, 2220 engagements


"$NKTR its absolutely nothing folks trust me"  
[X Link](https://x.com/PersimmonTI/status/1979237040303595576) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-17T17:24Z 10.3K followers, 11.3K engagements


"$XBI Watch the flow $PFE $MRK h/t @FL0WG0D"  
[X Link](https://x.com/PersimmonTI/status/1980030471544406224) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-19T21:57Z 10.3K followers, 3380 engagements


"$CGEM essentially my thesis for a small position 🤷🏻♀"  
[X Link](https://x.com/PersimmonTI/status/1980058518746284252) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-19T23:48Z 10.3K followers, 3901 engagements


"$XBI While not about biotech specifically this podcast episode is a must listen on the dynamics of US v. China. What China does well has done well for many many years is manufacture with precision at prodigious scale can see it in the speed of clinical trial enrollment can see it in the scope of their rare earth refining. What the US has/had always done well is in some ways the opposite innovate stochastically and move fast and break things by fostering that very spirit of freedom to try funding those tries and on failure funding some other tries Well China is no slouch to innovate anymore"  
[X Link](https://x.com/PersimmonTI/status/1980421626165674149) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-20T23:51Z 10.3K followers, 1758 engagements


"$PFE $xbi Pfizer on current business development capacity and priorities: $XX billion allocated which includes a $X billion drawdown for 3Sbio deal. Likely several smaller deals versus one large one. Areas of interest unchanged: oncology vaccines internal medicine (cardiometabolic obesity) and I&I. "  
[X Link](https://x.com/PersimmonTI/status/1954198685052535164) [@PersimmonTI](/creator/x/PersimmonTI) 2025-08-09T15:10Z 10.3K followers, 11.1K engagements


"The PBM of event ticket sales everyone $LYV"  
[X Link](https://x.com/PersimmonTI/status/1972094150096175249) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-28T00:20Z 10.3K followers, 10.2K engagements


"$PFE $xbi During $MTSR acquisition update call $PFE again guiding to $15B total allocation for M&A and here is the current breakdown: $2B 3Sbio PD1 x VEGF (oncology) $4.9B $MTSR obesity/cardio Which leaves $8B of firepower with as yet unaddressed key therapeutic areas of: vaccines (maybe $CDTX) I&I (maybe $KYMR $NKTR) "  
[X Link](https://x.com/PersimmonTI/status/1972494055977156931) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T02:50Z 10.3K followers, 8588 engagements


"$GMAB x $MRUS Its official Genmab to buy Merus for $8B $97/share all cash transaction. XX% premium to Merus closing price and no Centerview Partners just Jefferies. $MRUS is my largest holding $xbi"  
[X Link](https://x.com/PersimmonTI/status/1972604876858249277) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T10:10Z 10.3K followers, 7258 engagements


"$CYTK At Stifels recently on the realistic possibility of meaningful label and REMS differentiation vis a vis $BMY which could lead to meaningful commercial differentiation:"  
[X Link](https://x.com/PersimmonTI/status/1975367377115341179) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-07T01:07Z 10.3K followers, 4170 engagements


"$SLNO Go with Goldman"  
[X Link](https://x.com/PersimmonTI/status/1975959749570293938) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-08T16:21Z 10.3K followers, 3698 engagements


"$SLNO Its not perfect but its something. Its a ravenous literally insatiable hunger a drive for food that knows no bounds and drives its victims into morbid obesity with all of its associated co-morbidities. Its not perfect but it helps sate what was once insatiable it lessens that hunger drive. Not just on a survey in real life. Its not perfect but its something. Its doing some good. And to spread misinformation and/or improperly aggrandize safety data purely for profit isnt doing any good imho"  
[X Link](https://x.com/PersimmonTI/status/1976088969763848520) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T00:54Z 10.3K followers, 10.8K engagements


"$AKRO x $NVO BREAKING: Akero Therapeutics to be Acquired by Novo Nordisk for up to $XXX Billion. $XX Per Share in Cash and CVR of $X Per Share. $xbi"  
[X Link](https://x.com/PersimmonTI/status/1976229884478570927) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T10:14Z 10.3K followers, 6005 engagements


"$AKRO x $NVO This is a highly achievable $6/share CVR contingent on efruxifermin full approval:"  
[X Link](https://x.com/PersimmonTI/status/1976230818583339330) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T10:18Z 10.3K followers, 4634 engagements


"After $MRUS $AKRO was just about my largest position"  
[X Link](https://x.com/PersimmonTI/status/1976236607054471480) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T10:41Z 10.3K followers, 4373 engagements


"$SLNO Adding to Soleno here. And will continue to do so"  
[X Link](https://x.com/PersimmonTI/status/1976294118608327050) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T14:30Z 10.3K followers, 2915 engagements


"$XBI Its been too long and surely am tempting fate but"  
[X Link](https://x.com/PersimmonTI/status/1976393242599096612) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T21:04Z 10.3K followers, 1862 engagements


"$PALI hmmmm. determined to cancel its previously adjourned special meeting of stockholders (the Special Meeting) which had been scheduled to reconvene on Friday October XX 2025 at 10:00 a.m. Pacific Time"  
[X Link](https://x.com/PersimmonTI/status/1976403171221307720) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-09T21:43Z 10.3K followers, 7798 engagements


"$BMY x private Orbital $1.5B cash. The second recent private deal in vivo CAR T player in autoimmune disease after: $ABBV x Capstan earlier this year. @NatRevDrugDisc for more on the space see $SANA (though lentiviral) $xbi"  
[X Link](https://x.com/PersimmonTI/status/1976609398102384903) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-10T11:22Z 10.3K followers, 5695 engagements


"$JNJ $PTGX Per WSJ $JNJ in talks to buy $PTGX. The companies are currently in pact to develop icotrokinra an oral therapy forimmune diseases including plaque psoriasis and ulcerative colitis with JNJ having an exclusive license to commercialize the product. Potential implications for $ABVX Obe in UC. "  
[X Link](https://x.com/PersimmonTI/status/1976727285496488120) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-10T19:11Z 10.3K followers, 1980 engagements


"$XBI Perhaps apropos of the crypto situation and account wipeouts I challenge the schadenfreude because Ive been there And think Ive learned some lessons (but we will see). One of them: Once youve made money with a diversified as resilient as it can be portfolioits hard to go back to trying anything else"  
[X Link](https://x.com/PersimmonTI/status/1977385089278283917) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T14:45Z 10.3K followers, 2139 engagements


"$MDGL Added to my Madrigal position recently. Again have liked it and been long for a while mgmt doesnt get much better than Sibold imo. But the all-or-nothing buyout speculation wasnt/isnt constructive with $MDGL. Let resmetirom keep cooking and let come what may"  
[X Link](https://x.com/PersimmonTI/status/1977407483686830527) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T16:14Z 10.3K followers, 4562 engagements


"$xbi Does this count as generalist interest"  
[X Link](https://x.com/PersimmonTI/status/1977409816613306834) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T16:23Z 10.3K followers, 3192 engagements


"are we not allowed to italicize and/or bold anymore elon"  
[X Link](https://x.com/PersimmonTI/status/1977467256100577291) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T20:11Z 10.3K followers, 2435 engagements


"$XBI After successive takeouts of MASH FGF21 purveyors: Boston x $GSK $ETNB x $RHHBY $AKRO x $NOV What remains of the day and boxed in red Chinese options for those who dare: h/t @NatRevDrugDisc"  
[X Link](https://x.com/PersimmonTI/status/1977487380178460991) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T21:31Z 10.3K followers, 3631 engagements


"$RCUS $xbi Arcus (and $GILD) saying hold up just a minute to the TIGIT is dead thesis. No true control arm in this (puzzling) EDGE series of Phase 2s but these results are promising in cross-trial comparison to current standard of care in 1L gastric cancer CheckMate-649: Domvanalimab + zimberelimab + chemo with a XXXX mo. mOS and a XX% ORR Nivolumab + chemo with XXXX mo. mOS and a XX% ORR. Promising delta though caveat small N and no control. But note that a comparison to Nivolumab is coming in STAR-221"  
[X Link](https://x.com/PersimmonTI/status/1977521449272218106) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-12T23:47Z 10.3K followers, 6097 engagements


"$CATX For those who would like to sift through courtesy @nature cancer some cues as to why I think its good to keep things in Perspective headed into ESMO: "  
[X Link](https://x.com/PersimmonTI/status/1977692393777299744) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T11:06Z 10.3K followers, 2090 engagements


"$ADCT Nice private placement and much needed:"  
[X Link](https://x.com/PersimmonTI/status/1977699671599353978) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T11:35Z 10.3K followers, 2068 engagements


"$SRRK shake it off shake it off"  
[X Link](https://x.com/PersimmonTI/status/1977702848252064031) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T11:47Z 10.3K followers, 3321 engagements


"$XBI Not including what might happen with $PTGX x $JNJ Im going to predict that: $NAMS New Amsterdam will be the next company to be acquired with likely purchaser being $MRK $AZN $LLY or $AMGN. $NAMS obicetrapib has the potential to be a foundational oral Tx for CV health with an LDL-lowering plus approach LP(a) perhaps MACE outcomes benefit and perhaps Alzheimers prevention. PREVAIL doesnt read out for around another year yet but recent chart strength is indicating to me that at least one big pharma doesnt want to wait to find out (and pay a bigger price tag) $NAMS"  
[X Link](https://x.com/PersimmonTI/status/1977743508308894053) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T14:29Z 10.3K followers, 7887 engagements


"$IMAB And the market continues to wake up especially in light of China tensions potentially easing (tho this is no longer a Chinese company)"  
[X Link](https://x.com/PersimmonTI/status/1977774045622915209) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T16:30Z 10.3K followers, 3493 engagements


"$PTGX So a take under then"  
[X Link](https://x.com/PersimmonTI/status/1977829943519465539) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T20:12Z 10.3K followers, 5385 engagements


"$NAMS $AMGN ( $AKRO ) This is an interesting point but the answer in short is: Yes. Wouldn't be the first castaway that is brought back on board at a much dearer price for big pharma. And another note: if $NAMS obicetrapib is acquired that would make two $AMGN castoffs that were recently acquired for multiple billions. The other. $AKRO efruxifermin now proudly owned by $NVO"  
[X Link](https://x.com/PersimmonTI/status/1977831746180653460) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T20:20Z 10.3K followers, 4739 engagements


"$MRUS About those early phase X petosemtamab mCRC data Selected for Plenary Session Oral Presentation at AACR-NCI-EORTC International Conference: Initial interim data from the phase X trial evaluating petosemtamab in combination with standard chemotherapy in 1L and 2L metastatic colorectal cancer (mCRC) and as monotherapy in heavily pretreated (3L+) mCRC will be presented in a plenary session by Dr. Mohd Khushman M.D. Washington University School of Medicine St. Louis MO. I wonder if these early data will be any good $GMAB knew exactly what they were purchasing"  
[X Link](https://x.com/PersimmonTI/status/1977879766599708826) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T23:30Z 10.3K followers, 8502 engagements


"$NAMS Folks strangely enough a voice in mechanistic support of obicetrapibs effects comes from none other than Nassim Taleb "  
[X Link](https://x.com/PersimmonTI/status/1977883207279268098) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T23:44Z 10.3K followers, 5334 engagements


"$NAMS and another:"  
[X Link](https://x.com/PersimmonTI/status/1977883602013577339) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T23:46Z 10.3K followers, 3175 engagements


"Remember when you actually had to pay to make a trade Seems so antiquated now"  
[X Link](https://x.com/PersimmonTI/status/1978156101930455537) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T17:49Z 10.3K followers, 1297 engagements


"$ATXS I wish I had gone ahead and bought some $ATXS in speculation re: their AD asset. 😂"  
[X Link](https://x.com/PersimmonTI/status/1978160838277005519) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T18:07Z 10.3K followers, 2664 engagements


"my favorite time of year and have learned to never judge a persimmon by its cover "  
[X Link](https://x.com/PersimmonTI/status/1978261793534312852) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-15T00:49Z 10.3K followers, 1803 engagements


"Does $LNTH want it all $RADX"  
[X Link](https://x.com/PersimmonTI/status/1978417037903876413) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-15T11:05Z 10.3K followers, 8304 engagements


"$XBI the thing is even after this recent run up there is still a great dislocation in value for many assets/companies out there such were the depths of the nadir"  
[X Link](https://x.com/PersimmonTI/status/1978581799883116844) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-15T22:00Z 10.3K followers, 2240 engagements


"$IMNM $BCAB"  
[X Link](https://x.com/PersimmonTI/status/1978802820338868402) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T12:38Z 10.3K followers, 2814 engagements


"Do we count Betaville as being correct on $AKRO 🤔"  
[X Link](https://x.com/PersimmonTI/status/1978892008715424100) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T18:33Z 10.3K followers, 2984 engagements


"act like youve been here before"  
[X Link](https://x.com/PersimmonTI/status/1979238444107751595) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-17T17:29Z 10.3K followers, 1808 engagements


"@bio_clouseau"  
[X Link](https://x.com/PersimmonTI/status/1979552720236216489) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-18T14:18Z 10.3K followers, XXX engagements


"not doing something NOW because it would admit that you should have done something else THEN is a blunder. Ive done it before but trying not to do it again"  
[X Link](https://x.com/PersimmonTI/status/1979608891005817063) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-18T18:01Z 10.3K followers, 1548 engagements


"@raffcolo @Nature"  
[X Link](https://x.com/PersimmonTI/status/1979734679566909779) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-19T02:21Z 10.3K followers, XXX engagements


"@fakepharmabro here we go a $gern"  
[X Link](https://x.com/PersimmonTI/status/1977841555756232912) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T20:59Z 10.3K followers, 1063 engagements


"$XBI Let's go for a Takeout Tuesday tomorrow morning folks"  
[X Link](https://x.com/PersimmonTI/status/1977828004106514541) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-13T20:05Z 10.3K followers, 8634 engagements


"$BCAX $MRUS $PYXS Three HNSCC players unlike in dignity in fair Verona. $MRUS was/is the best $BCAX the best of the rest and like it here -- not bad valuation for a Tx that works in HNSCC. $PYXS. no comment"  
[X Link](https://x.com/PersimmonTI/status/1978159196961931416) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-14T18:01Z 10.3K followers, 3118 engagements


"$XBI There had better not be any buyouts tomorrow morning 😡"  
[X Link](https://x.com/PersimmonTI/status/1978568593697599692) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-15T21:08Z 10.3K followers, 4900 engagements


"$PRAX Double P3 hit on essential tremor more than doubles in value. $xbi"  
[X Link](https://x.com/PersimmonTI/status/1978781950283255856) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-16T11:15Z 10.3K followers, 4633 engagements


"$MTSR Didnt take too long to find out what $PFE bought:"  
[X Link](https://x.com/PersimmonTI/status/1972768364516024760) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-29T21:00Z 10.3K followers, 27.6K engagements


"$XBI I am probably wrong. but I just don't think it's very likely that $GPCR doesn't get taken out by big pharma at some point. The "obesity in a kit" companies are scarce (won't see $MTSR no more.) and those which are US based scarcer still. Tell me why I'm wrong please"  
[X Link](https://x.com/PersimmonTI/status/1973112534183059734) [@PersimmonTI](/creator/x/PersimmonTI) 2025-09-30T19:47Z 10.3K followers, 14.3K engagements


"$XBI A Visual History of Approved ADCs courtesy @nature cancer:"  
[X Link](https://x.com/PersimmonTI/status/1979601361227452610) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-18T17:31Z 10.3K followers, 13.7K engagements


"$SMMT $AKESF HARMONi-6 Still Chinese data still impressive now in first line NSCLC against Tislelizumab. Still no OS "  
[X Link](https://x.com/PersimmonTI/status/1979927758089212030) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-19T15:08Z 10.3K followers, 5712 engagements


"$SLNO Betaville rumor and many insider sells Im talking of course about: $AKRO take a look at CEO Cheng and Co.s steady sells for months leading up until $NVO takeout. Meaningless either way "  
[X Link](https://x.com/PersimmonTI/status/1980438720265482379) [@PersimmonTI](/creator/x/PersimmonTI) 2025-10-21T00:59Z 10.3K followers, 6496 engagements