[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@boredbuyside BB
BB posts on X about potent, $4578t, $4768t, wk the most. They currently have XXX followers and XX posts still getting attention that total XXX engagements in the last XX hours.
Engagements: XXX #
- X Week XXX +386%
- X Months XXX -XX%
- X Year XXXXX +24%
Mentions: X #
Followers: XXX #
- X Week XXX +5.30%
- X Months XXX +16%
CreatorRank: XXXXXXXXX #
Social Influence #
Social topic influence potent 15.38%, $4578t #9, $4768t #9, wk 7.69%, superior XXXX%
Top Social Posts #
Top posts by engagements in the last XX hours
"This ultra-low Kd suggests maximum neutralization potential in HS. Since IL-1 is a fundamental upstream driver a highly potent and selective blocker like AVTX-009 aims to suppress the inflammatory cascade effectively"
X Link @boredbuyside 2025-10-14T18:44Z XXX followers, XX engagements
"Am I right in thinking there are only two ways to play IL-1RAP publicly - Almirall & Otsuka Otsuka at least says it minimized the effector function which is what we want in autoimmune dz. Struggle to find much on the Almirall/Inchnos molecule"
X Link @boredbuyside 2025-10-15T13:52Z XXX followers, XX engagements
"An anti-IL-1 agent (like AVTX-009) works because IL-1 is UPSTREAM of IL-17 and TNF. Blocking this "spark" halts the inflammatory cascade specifically reducing IL-17 production and the resulting neutrophilic inflammation"
X Link @boredbuyside 2025-10-14T18:38Z XXX followers, XX engagements
"BIMZELX treats HS by disrupting the potent IL-17 pathway reducing neutrophil recruitment & tissue damage. Phase X trials showed HiSCR50 achieved in 48-52% of Q2W patients vs. 29-32% on placebo at Wk XX. This validates IL-17 as a key target"
X Link @boredbuyside 2025-10-14T18:38Z XXX followers, XX engagements
"Anakinra (IL-1Ra) is a recombinant antagonist blocking both IL-1/ signaling. It binds the IL-1R1 receptor tightly (Kd XXX pM). Due to its short serum half-life (46 h) it requires daily SC injection"
X Link @boredbuyside 2025-10-14T18:44Z XXX followers, XX engagements
"I guess Cantargia (source of Otsuka molecule) is another way but micro-cap with an oncology focus that doesn't make much sense"
X Link @boredbuyside 2025-10-15T15:02Z XXX followers, XXX engagements
"AVTX-009 (formerly LY2189102) is an IL-1-specific mAb (IgG4) with ultra-high affinity: Kd XXXX pM. This superior affinity significantly tighter than other IL-1 antagonists is characterized by an extremely slow off-rate"
X Link @boredbuyside 2025-10-14T18:44Z XXX followers, XX engagements
"IL-1RAP would address IL-1a/b question in addition to addressing IL-33 & IL-36 which would bring in pulmonary indications & pustular diseases"
X Link @boredbuyside 2025-10-15T13:52Z XXX followers, XXX engagements
"Both IL-1 and its sibling IL-1 signal via the same IL-1R1 receptor complex. IL-1 however is considered an "alarmin" released upon cell damage and its expression is only minimally increased in HS lesions"
X Link @boredbuyside 2025-10-14T18:44Z XXX followers, XXX engagements