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# ONC

ONC's BRUKINSA shows strong PFS data in frontline CLL, while its BTK degrader also posts high ORR. However, concerns arise regarding sonrotoclax safety with TEAE-related deaths noted in a trial.

### About ONC
ONC refers to BeOne Medicines, a biopharmaceutical company focused on oncology treatments.  

### Insights
- onc sentiment is up XXXXX% from the previous month.

### Engagements: XXX (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:onc/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/onc/time-series/interactions.tsv)  
Current Value: XXX  
Daily Average: XXXXXXX  
X Week: XXXXXX -XX%  
X Month: XXXXXXX -XX%  
X Months: XXXXXXXXXX +103%  
X Year: XXXXXXXXXX +293%  
1-Year High: XXXXXXXXXX on 2025-08-11  
1-Year Low: X on 2025-11-04  

Engagements by network (24h):
Reddit: XX
TikTok: XX
X: XX
YouTube: XXX

  
  
### Mentions: XX (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:onc/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/onc/time-series/posts_active.tsv)  
Current Value: XX  
Daily Average: XXX  
X Week: XXX -XX%  
X Month: XXXXX +44%  
X Months: XXXXX +21%  
X Year: XXXXXX +118%  
1-Year High: XXX on 2025-06-28  
1-Year Low: X on 2025-11-02  

Mentions by network (24h):
Reddit: X
TikTok: X
X: XX
YouTube: X

  
  
### Creators: XX (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:onc/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/onc/time-series/contributors_active.tsv)  
XX unique social accounts have posts mentioning ONC in the last XX hours which is down XX% from XX in the previous XX hours
Daily Average: XXX  
X Week: XXX -XX%  
X Month: XXX +31%  
X Months: XXXXX +29%  
X Year: XXXXX +110%  
1-Year High: XXX on 2025-06-28  
1-Year Low: X on 2025-11-02  

The most influential creators that mention ONC in the last XX hours

| Creator                                              | Rank | Followers | Posts | Engagements |
| -------                                              | ---- | --------- | ----- | ----------- |
| [@AponiaAnalytics](/creator/twitter/AponiaAnalytics) | X    | XXXXX     | X     | XX          |

[View More](/list/creators/onc/100)
  
  
### Sentiment: XX%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:onc/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/onc/time-series/sentiment.tsv)  
Current Value: XX%  
Daily Average: XX%  
X Week: XXX% +27%  
X Month: XXX% +43%  
X Months: XXX% +22%  
X Year: XXX% +26%  
1-Year High: XXX% on 2025-11-02  
1-Year Low: X% on 2025-06-24  

Most Supportive Themes:
- Oncology Research and Treatment: (30%) Discussions around advancements in cancer research, clinical trials, and treatment methodologies, particularly in breast cancer and general oncology.
- Medical Professionals and Education: (25%) Content featuring medical professionals, their experiences, educational insights, and discussions within the medical community, including nursing and specialized fields.
- Healthcare System and Policy: (20%) Posts touching upon healthcare systems, policy discussions, and the operational aspects of medical institutions, including recruitment and program development.
  
Most Critical Themes:
- Geopolitical and Social Commentary: (15%) Content expressing strong opinions on geopolitical events, immigration, and social issues, often with a critical or controversial stance.
- Criticism of Media and Institutions: (10%) Posts that criticize media outlets or international organizations for their perceived biases or inaction on certain global issues.
  

### Top ONC Social Posts
Top posts by engagements in the last XX hours

*Showing only X posts for non-authenticated requests. Use your API key in requests for full results.*

"$ONC 🦉 BeOne flags standout ASH data: BRUKINSA hit XX% six-year PFS in frontline CLL and topped ibrutinib in long-term R/R follow-up. And BTK degrader BGB-16673 posted XX% ORR in heavily pretreated CLL"  
[X Link](https://x.com/AponiaAnalytics/status/1998127485205250475) [@AponiaAnalytics](/creator/x/AponiaAnalytics) 2025-12-08T20:28Z 5121 followers, XXX engagements


"I actually want ONC to do "doomed one-sided attraction because of sexuality " in Season 5"  
[Reddit Link](https://redd.it/1phl9mn) [@TRDraqula](/creator/reddit/TRDraqula) 2025-12-08T19:16Z X followers, XXX engagements


"$ONC 🦉 BRUKINSA posts a shockingly strong XX% six-year PFS in frontline CLL while BeOnes BTK degrader delivers XX% ORR at RP2D. The data tightens its grip on the CLL market"  
[X Link](https://x.com/AponiaAnalytics/status/1998077142190686613) [@AponiaAnalytics](/creator/x/AponiaAnalytics) 2025-12-08T17:08Z 5121 followers, XXX engagements


"$ONC assuages sonrotoclax safety concerns with full presentation at #ASH25"  
[X Link](https://x.com/ByMadeleineA/status/1998056058984530274) [@ByMadeleineA](/creator/x/ByMadeleineA) 2025-12-08T15:44Z 8161 followers, XXX engagements