# Upstream Bio, Inc. (UPB)

Upstream Bio's Phase [--] trial data for severe asthma drug Verekitug released, showing mixed efficacy across dosing regimens. Stock price plummets over 30% following the announcement.

### About Upstream Bio, Inc.
Upstream Bio, Inc. is a biotechnology company focused on developing treatments for severe conditions.  
Upstream Bio, Inc. uses the ticker $UPB for trading. Listed in the [Stocks](/list/stocks) category.

### Insights
- Upstream Bio, Inc. (UPB) trading volume is up 715.28% from the previous month.
- Upstream Bio, Inc. (UPB) social dominance is up 1772.22% from the previous year.
- Upstream Bio, Inc. (UPB) Galaxy Score™ is up 80.77% from the previous month.
- Upstream Bio, Inc. (UPB) sentiment is up 90.91% from the previous week.
- Upstream Bio, Inc. (UPB) creators is up 163.16% from the previous week.
- Upstream Bio, Inc. (UPB) engagements is up 426.2% from the previous week.
- Upstream Bio, Inc. (UPB) mentions is up 120.17% from the previous week.
- Upstream Bio, Inc. (UPB) posts created is up 901.21% from the previous year.
- Upstream Bio, Inc. Mentions hit a 52-Week high of [---] for the day
- Upstream Bio, Inc. Mentions hit an all time of [---] for the day
- Upstream Bio, Inc. Galaxy Score™ hit a 52-Week high of [--] for the hour
- Upstream Bio, Inc. Galaxy Score™ hit an all time of [--] for the hour
- Upstream Bio, Inc. Price hit a 52-Week high of $32.80 for the hour
- Upstream Bio, Inc. Price hit an all time of $32.80 for the hour

### Price: $8.80
![Price Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:close/iv:1d.svg)  
[Price 24-Hour Time-Series Raw Data](/topic/$upb/time-series/close.tsv)  
The stock price has experienced a significant decline, dropping over 30% in the last [--] hours, following the release of Phase [--] trial data for their severe asthma drug, Verekitug. Mixed efficacy results appear to have spooked investors, leading to a sharp sell-off.  

24-Hour: -31.25%
7-Day: -66.6%
30-Day: -71.77%

1-Year High: $32.60 on 2026-01-13  
1-Year Low: $8.80 on 2026-02-13  
  
  
### AltRank: [---]
![AltRank Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:alt_rank/iv:1d.svg)  
[AltRank 24-Hour Time-Series Raw Data](/topic/$upb/time-series/alt_rank.tsv)  
Upstream Bio, Inc. (UPB) is currently AltRank #642 based on combined combined social and market metrics
Daily Average: [-----]  
[--] Week: [---] +56  
1-Year High: [-----] on 2026-02-05  
1-Year Low: [---] on 2026-01-25  
  
  
### Galaxy Score: [-----]
![Galaxy Score Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:galaxy_score/iv:1d.svg)  
[Galaxy Score 24-Hour Time-Series Raw Data](/topic/$upb/time-series/galaxy_score.tsv)  
Current Value: [-----]  
Daily Average: [--]  
[--] Week: [--] +14  
[--] Month: [--] +21  
[--] Months: [--] +2  
[--] Year: [--] [---]  
1-Year High: [--] on 2026-01-26  
1-Year Low: [--] on 2025-10-02  
  
  
### Engagements: [------] (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/$upb/time-series/interactions.tsv)  
Current Value: [------]  
Daily Average: [-----]  
[--] Week: [-------] +426%  
[--] Month: [-------] +301%  
[--] Months: [-------] +7.90%  
[--] Year: [---------] +265%  
1-Year High: [-------] on 2025-03-11  
1-Year Low: [--] on 2025-05-09  

Engagements by network (24h):
Reddit: [--]
YouTube: [--]
X: [------]
News: [--]

  
  
### Mentions: [---] (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/$upb/time-series/posts_active.tsv)  
Current Value: [---]  
Daily Average: [--]  
[--] Week: [---] +120%  
1-Year High: [---] on 2026-02-13  
1-Year Low: [--] on 2025-05-09  

Mentions by network (24h):
Reddit: [--]
YouTube: [--]
X: [---]
News: [--]

  
  
### Creators: [---] (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/$upb/time-series/contributors_active.tsv)  
[---] unique social accounts have posts mentioning Upstream Bio, Inc. (UPB) in the last [--] hours which is down 22% from [---] in the previous [--] hours
Daily Average: [--]  
[--] Week: [---] +163%  
1-Year High: [---] on 2025-06-28  
1-Year Low: [--] on 2025-05-09  

The most influential creators that mention Upstream Bio, Inc. in the last [--] hours

| Creator                                              | Rank | Followers | Posts | Engagements |
| -------                                              | ---- | --------- | ----- | ----------- |
| [@BiopharmIQ](/creator/twitter/BiopharmIQ)           | [--]    | [------]    | [--]     | [-----]       |
| [@stocktreats](/creator/twitter/stocktreats)         | [--]    | [-----]     | [--]     | [---]         |
| [@BPharmCatalyst](/creator/twitter/BPharmCatalyst)   | [--]    | [------]    | [--]     | [---]         |
| [@OptionRunners](/creator/twitter/OptionRunners)     | [--]    | [------]    | [--]     | [---]         |
| [@BOSSTRADING0](/creator/twitter/BOSSTRADING0)       | [--]    | [-----]     | [--]     | [---]         |
| [@ElMonoGran42994](/creator/twitter/ElMonoGran42994) | [--]    | [---]       | [--]     | [---]         |
| [@monaco_biotech](/creator/twitter/monaco_biotech)   | [--]    | [-----]     | [--]     | [---]         |
| [@RosaJim94865433](/creator/twitter/RosaJim94865433) | [--]    | [---]       | [--]     | [---]         |
| [@BiotechTV](/creator/twitter/BiotechTV)             | [--]    | [------]    | [--]     | [---]         |
| [@MiriamF24887120](/creator/twitter/MiriamF24887120) | [--]   | [--]        | [--]     | [---]         |

[View More](/list/creators/$upb/100)
  
  
### Sentiment: 59%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/$upb/time-series/sentiment.tsv)  
Current Value: 59%  
Daily Average: 82%  
[--] Week: 63% +30%  
[--] Month: 52% +10%  
[--] Months: 52% +2%  
[--] Year: 52% -48%  
1-Year High: 100% on 2025-02-15  
1-Year Low: 10% on 2026-01-20  

Most Supportive Themes:
- Creator Engagement: (99%) The number of engagements on posts mentioning $upb has seen a significant increase over the past year, indicating growing community interest and interaction.
- Creator Activity: (95%) The number of unique creators posting about $upb has also shown substantial growth over the past year, suggesting a broadening base of influencers discussing the topic.
  
Most Critical Themes:
- Recent Engagement Dip: (-71%) While yearly trends are positive, recent 24-hour engagements are down significantly compared to the daily average, suggesting a temporary lull in immediate community buzz.
- Mentions Decline: (-71%) The number of mentions has decreased over the past month, which could indicate a slight reduction in overall conversation volume around $upb.
  
  
  
### Social Dominance: 0.021%
![Social Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:social_dominance/iv:1d.svg)  
[Social Dominance 24-Hour Time-Series Raw Data](/topic/$upb/time-series/social_dominance.tsv)  
Current Value: 0.021%  
Daily Average: 0.00431%  
[--] Week: 0.017% +0.015%  
[--] Month: 0.034% +0.03%  
[--] Months: 0.034% +0.031%  
[--] Year: 0.034% +0.032%  
1-Year High: 0.049% on 2025-03-11  
1-Year Low: 0.0002% on 2025-05-09  
  
  
### Market Dominance: 0.0005385293472783949%
![Market Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:market_dominance/iv:1d.svg)  
[Market Dominance 24-Hour Time-Series Raw Data](/topic/$upb/time-series/market_dominance.tsv)  
Current Value: 0.0005385293472783949%  
Daily Average: 0%  
1-Year High: 0.00205% on 2026-01-13  
1-Year Low: 0.00054% on 2026-02-14  
  
  
### Market Cap: $475,539,601
![Market Cap Line Chart](https://lunarcrush.com/gi/w:600/t:$upb/c:line/m:market_cap/iv:1d.svg)  
[Market Cap 24-Hour Time-Series Raw Data](/topic/$upb/time-series/market_cap.tsv)  
Current Value: $475,539,601  
Daily Average: $1,498,572,005  
[--] Week: $475,539,601 -66%  
[--] Month: $472,837,671 -72%  
1-Year High: $1,761,658,067 on 2026-01-13  
1-Year Low: $472,837,671 on 2026-02-13  

### Top Upstream Bio, Inc. Social Posts
Top posts by engagements in the last [--] hours

*Showing a maximum of [--] top social posts without a LunarCrush subscription.*

"🧬 Biotech Weekly News Largest single-day stock moves during the week ending 02/13/26 📈 $EVMN 71% EVO301 Topline data $NKTR 51% REZOLVE-AD Maintenance Data $HUMA 30% New Defense Funding for Blood Vessels $PHIO 24% Positive SMC wrap-up on PH-762 $NVCR 19% FDA Approves Optune Pax for Cancer 📉 $UPB -47% VALIANT Trial Results $MCRB -42% Program and Corporate Updates $CHRS -20% Pricing of Public Offering $1.75/sh $OKYO -19% Pricing of $20M Offering $1.85/sh $RGNX -14% Regulatory Update on RGX-121 BLA See image below. *** AD momentum continues. $NKTR maintenance data + early Ph2a from $EVMN in a"  
[X Link](https://x.com/BiopharmIQ/status/2022672827145650554) [@BiopharmIQ](/creator/x/BiopharmIQ) 2026-02-14T14:02Z 28.9K followers, [----] engagements


"$UPB- $CGTL- $ELPW   # #_ # https://x.com/messages/composerecipient_id=2000471938528092160 https://x.com/messages/composerecipient_id=2000471938528092160"  
[X Link](https://x.com/layaal_ahmed654/status/2022643800775307571) [@layaal_ahmed654](/creator/x/layaal_ahmed654) 2026-02-14T12:07Z [--] followers, [---] engagements


"VIDEO: U.S. Stock Markets Evening Report Price Actions Recap - (26/02/13) Featured Stocks: $ATOM $FSLY $MGRT $MITK $CRSR $CGTL $PLYX $PFSA $HCWB $UPB $AEHL $NUS $TWAV $TPH $BFAM . #stocks #stockmarket #stockstowatch #stockinsights https://www.youtube.com/watchv=mn0udBC79Z8 https://www.youtube.com/watchv=mn0udBC79Z8"  
[X Link](https://x.com/stocktreats/status/2022515931713261878) [@stocktreats](/creator/x/stocktreats) 2026-02-14T03:39Z [----] followers, [---] engagements


"New 3-Month Lows (Top 10): $POAS -83.490% $INTS -32.580% $UPB -31.640% $ONCO -26.950% $OBAI -26.350% $LIMN -22.490% $IRON -21.910% $TWAV -21.800% $HCWB -21.230% $BFAM -18.250% #stocks #stockmarket #stockstowatch"  
[X Link](https://x.com/stocktreats/status/2022465390597595348) [@stocktreats](/creator/x/stocktreats) 2026-02-14T00:18Z [----] followers, [---] engagements

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