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# Protagonist Therapeutics, Inc (PTGX)

Protagonist Therapeutics (PTGX) presents positive 52-week data for Rusfertide at ASH 2025, showing durable response and hematocrit control in Polycythemia Vera. The company also expects a BLA submission for Rusfertide in Q4 2025, fueling investor optimism.

### About Protagonist Therapeutics, Inc
Protagonist Therapeutics, Inc. is a biotechnology company focused on developing novel peptide-based therapeutics.  
Protagonist Therapeutics, Inc uses the ticker $PTGX for trading. Listed in the [Stocks](/list/stocks) category within the [Healthcare](/list/stocks/healthcare) sectors.

### Insights
- Protagonist Therapeutics, Inc (PTGX) social dominance hit XXXXXX which is XXX% higher than it's daily average.
- Protagonist Therapeutics, Inc (PTGX) trading volume is up XXXXXX% from the previous week.
- Protagonist Therapeutics, Inc (PTGX) social dominance is up 1287.5% from the previous year.
- Protagonist Therapeutics, Inc Price hit a 52-Week high of $XXXXX for the hour
- Protagonist Therapeutics, Inc Price hit an all time of $XXXXX for the hour

### Price: $XXXXX
![Price Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:close/iv:1d.svg)  
[Price 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/close.tsv)  
The stock price is near a 52-week high, driven by positive clinical trial results for icotrokinra, increased social engagement, and speculation about a potential acquisition by Johnson & Johnson, leading to higher trading volumes.  

24-Hour: -XXXX%
7-Day: XXXX%
30-Day: XXXX%

1-Year High: $XXXXX on 2025-12-08  
1-Year Low: $XXXXX on 2025-02-25  
  
  
### AltRank: XXX
![AltRank Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:alt_rank/iv:1d.svg)  
[AltRank 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/alt_rank.tsv)  
Protagonist Therapeutics, Inc (PTGX) is currently AltRank #260 based on combined combined social and market metrics
Daily Average: XXX  
X Week: XXX +66  
X Month: XXX +1  
X Months: XXX -XX  
1-Year High: XXXXX on 2025-08-07  
1-Year Low: XX on 2025-10-10  
  
  
### Galaxy Score: XXXXX
![Galaxy Score Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:galaxy_score/iv:1d.svg)  
[Galaxy Score 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/galaxy_score.tsv)  
Current Value: XXXXX  
Daily Average: XX  
X Week: XX -XX  
X Month: XX -XX  
X Months: XX -XX  
1-Year High: XX on 2025-03-10  
1-Year Low: XX on 2025-08-01  
  
  
### Engagements: XXXXXX (24h)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:interactions/iv:1d.svg)  
[Engagements 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/interactions.tsv)  
Current Value: XXXXXX  
Daily Average: XXXXXX  
X Week: XXXXXXX -XX%  
X Month: XXXXXXXXX -XX%  
X Months: XXXXXXXXXX +1,089%  
X Year: XXXXXXXXXX +1,103%  
1-Year High: XXXXXXXXX on 2025-11-01  
1-Year Low: XXX on 2025-08-01  

Engagements by network (24h):
Reddit: XXX
TikTok: XXXXX
X: XXXXXX
YouTube: XXXXXX

  
  
### Mentions: XXX (24h)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:posts_active/iv:1d.svg)  
[Mentions 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/posts_active.tsv)  
Current Value: XXX  
Daily Average: XX  
X Week: XXX -XXXX%  
X Month: XXXXX -X%  
X Months: XXXXX +561%  
X Year: XXXXX +854%  
1-Year High: XXX on 2025-06-28  
1-Year Low: XX on 2025-02-04  

Mentions by network (24h):
Reddit: XX
TikTok: XXX
X: XXX
YouTube: XXX

  
  
### Creators: XXX (24h)
![Creators Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:contributors_active/iv:1d.svg)  
[Creators 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/contributors_active.tsv)  
XXX unique social accounts have posts mentioning Protagonist Therapeutics, Inc (PTGX) in the last XX hours which is down XX% from XXX in the previous XX hours
Daily Average: XX  
X Week: XXX -XXXX%  
X Month: XXXXX -XX%  
X Months: XXXXX +977%  
X Year: XXXXX +1,229%  
1-Year High: XXX on 2025-06-28  
1-Year Low: X on 2025-01-28  

The most influential creators that mention Protagonist Therapeutics, Inc in the last XX hours

| Creator                                                    | Rank | Followers | Posts | Engagements |
| -------                                                    | ---- | --------- | ----- | ----------- |
| [@art](/creator/youtube/art)                               | X    | XXXXXXX   | X     | XXXXX       |
| [@semodough](/creator/twitter/semodough)                   | X    | XXXXXX    | X     | XXXXX       |
| [@Biotech2k1](/creator/twitter/Biotech2k1)                 | X    | XXXXXX    | XX    | XXX         |
| [@yodaez](/creator/youtube/yodaez)                         | X    | XXXXXX    | X     | XXX         |
| [@doepke_michel](/creator/twitter/doepke_michel)           | X    | XXXXX     | X     | XXX         |
| [@protocolrecordings](/creator/youtube/protocolrecordings) | X    | XXXXXXX   | X     | XXX         |
| [@AponiaAnalytics](/creator/twitter/AponiaAnalytics)       | X    | XXXXX     | X     | XX          |
| [@seedytx19](/creator/twitter/seedytx19)                   | X    | XXXXX     | X     | XX          |
| [@ChartMill](/creator/twitter/ChartMill)                   | X    | XXXXXX    | X     | XX          |
| [@rezfszubagoly](/creator/twitter/rezfszubagoly)           | XX   | XXX       | X     | XX          |

[View More](/list/creators/$ptgx/100)
  
  
### Sentiment: XX%
![Sentiment Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:sentiment/iv:1d.svg)  
[Sentiment 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/sentiment.tsv)  
Current Value: XX%  
Daily Average: XX%  
X Week: XX% +7%  
X Month: XX% +4%  
X Months: XX% -XX%  
X Year: XX% -XX%  
1-Year High: XXX% on 2024-12-11  
1-Year Low: XX% on 2025-01-01  

Most Supportive Themes:
- Positive Clinical Trial Results: (40%) Protagonist Therapeutics announced positive clinical trial results for icotrokinra, a novel peptide-based therapeutic for psoriasis.
- Increased Trading Volume and Social Activity: (35%) Significant increases in trading volume, social dominance, and engagements indicate heightened market interest and community interaction.
- Analyst Recommendations and Price Targets: (15%) Analyst ratings and price targets suggest potential upside, contributing to positive sentiment and investor confidence.
  
Most Critical Themes:
- Market Volatility and General Market Sentiment: (10%) Overall market sentiment is neutral, with some discussions acknowledging general market volatility.
  
  
  
### Social Dominance: XXXXX%
![Social Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:social_dominance/iv:1d.svg)  
[Social Dominance 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/social_dominance.tsv)  
Current Value: XXXXX%  
Daily Average: XXXXX%  
X Week: XXXXX% +0.0054%  
X Month: XXXXX% +0.058%  
X Months: XXXXX% +0.082%  
X Year: XXXXX% +0.082%  
1-Year High: XXXXX% on 2025-12-10  
1-Year Low: XXXXX% on 2025-09-07  
  
  
### Market Dominance: XXXXXXX%
![Market Dominance Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:market_dominance/iv:1d.svg)  
[Market Dominance 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/market_dominance.tsv)  
Current Value: XXXXXXX%  
Daily Average: X%  
1-Year High: XXXXX% on 2025-03-31  
1-Year Low: XXXXXXX% on 2025-02-27  
  
  
### Market Cap: $XXXXXXXXXXXXX
![Market Cap Line Chart](https://lunarcrush.com/gi/w:600/t:$ptgx/c:line/m:market_cap/iv:1d.svg)  
[Market Cap 24-Hour Time-Series Raw Data](/topic/$ptgx/time-series/market_cap.tsv)  
Current Value: $XXXXXXXXXXXXX  
Daily Average: $XXXXXXXXXXXXX  
X Week: $XXXXXXXXXXXXX +$4.80%  
X Month: $XXXXXXXXXXXXX +$12%  
X Months: $XXXXXXXXXXXXX +$59%  
1-Year High: $XXXXXXXXXXXXX on 2025-12-08  
1-Year Low: $XXXXXXXXXXXXX on 2025-02-27  

### Top Protagonist Therapeutics, Inc Social Posts
Top posts by engagements in the last XX hours

*Showing only X posts for non-authenticated requests. Use your API key in requests for full results.*

"214 high prot low carb low cal huge dinner bowl"  
[Reddit Link](https://redd.it/1pijiue) [@seven_1312](/creator/reddit/seven_1312) 2025-12-09T21:24Z X followers, XX engagements


"@TalonFey7 @AdinHaykin1 This is not from the Roman Catholic Church. This is the Orthodox Church Canon law and the apostolic canons which predate the Bible. Wake up silly prot. Youre in a cult"  
[X Link](https://x.com/wrightwingman/status/1998403769835352234) [@wrightwingman](/creator/x/wrightwingman) 2025-12-09T14:46Z 2115 followers, XXX engagements


"wts lfb blackpink ph Up Blackpink funko pop pink venom X pack (Hot topic exclusive) Repriced from 3700 + XXX for the protector "to 2950" - price : 2950 w/ prot na *See alt T. Deadline blackpink blink jennie lisa jisoo ros shutdown collector collection figure born pink"  
[X Link](https://x.com/zashikko/status/1998251392583266504) [@zashikko](/creator/x/zashikko) 2025-12-09T04:40Z XXX followers, XXX engagements


"🎢🎡 "Interplanetarian (The Ride Home Remix) 🎢🎡"  
[YouTube Link](https://youtube.com/watch?v=vG6D0LAvkgY) [@toyboxnostalgia](/creator/youtube/toyboxnostalgia) 2025-12-08T22:01Z 1510 followers, XX engagements

[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

Protagonist Therapeutics, Inc (PTGX)

Protagonist Therapeutics (PTGX) presents positive 52-week data for Rusfertide at ASH 2025, showing durable response and hematocrit control in Polycythemia Vera. The company also expects a BLA submission for Rusfertide in Q4 2025, fueling investor optimism.

About Protagonist Therapeutics, Inc

Protagonist Therapeutics, Inc. is a biotechnology company focused on developing novel peptide-based therapeutics.
Protagonist Therapeutics, Inc uses the ticker $PTGX for trading. Listed in the Stocks category within the Healthcare sectors.

Insights

  • Protagonist Therapeutics, Inc (PTGX) social dominance hit XXXXXX which is XXX% higher than it's daily average.
  • Protagonist Therapeutics, Inc (PTGX) trading volume is up XXXXXX% from the previous week.
  • Protagonist Therapeutics, Inc (PTGX) social dominance is up 1287.5% from the previous year.
  • Protagonist Therapeutics, Inc Price hit a 52-Week high of $XXXXX for the hour
  • Protagonist Therapeutics, Inc Price hit an all time of $XXXXX for the hour

Price: $XXXXX

Price Line Chart
Price 24-Hour Time-Series Raw Data
The stock price is near a 52-week high, driven by positive clinical trial results for icotrokinra, increased social engagement, and speculation about a potential acquisition by Johnson & Johnson, leading to higher trading volumes.

24-Hour: -XXXX% 7-Day: XXXX% 30-Day: XXXX%

1-Year High: $XXXXX on 2025-12-08
1-Year Low: $XXXXX on 2025-02-25

AltRank: XXX

AltRank Line Chart
AltRank 24-Hour Time-Series Raw Data
Protagonist Therapeutics, Inc (PTGX) is currently AltRank #260 based on combined combined social and market metrics Daily Average: XXX
X Week: XXX +66
X Month: XXX +1
X Months: XXX -XX
1-Year High: XXXXX on 2025-08-07
1-Year Low: XX on 2025-10-10

Galaxy Score: XXXXX

Galaxy Score Line Chart
Galaxy Score 24-Hour Time-Series Raw Data
Current Value: XXXXX
Daily Average: XX
X Week: XX -XX
X Month: XX -XX
X Months: XX -XX
1-Year High: XX on 2025-03-10
1-Year Low: XX on 2025-08-01

Engagements: XXXXXX (24h)

Engagements Line Chart
Engagements 24-Hour Time-Series Raw Data
Current Value: XXXXXX
Daily Average: XXXXXX
X Week: XXXXXXX -XX%
X Month: XXXXXXXXX -XX%
X Months: XXXXXXXXXX +1,089%
X Year: XXXXXXXXXX +1,103%
1-Year High: XXXXXXXXX on 2025-11-01
1-Year Low: XXX on 2025-08-01

Engagements by network (24h): Reddit: XXX TikTok: XXXXX X: XXXXXX YouTube: XXXXXX

Mentions: XXX (24h)

Mentions Line Chart
Mentions 24-Hour Time-Series Raw Data
Current Value: XXX
Daily Average: XX
X Week: XXX -XXXX%
X Month: XXXXX -X%
X Months: XXXXX +561%
X Year: XXXXX +854%
1-Year High: XXX on 2025-06-28
1-Year Low: XX on 2025-02-04

Mentions by network (24h): Reddit: XX TikTok: XXX X: XXX YouTube: XXX

Creators: XXX (24h)

Creators Line Chart
Creators 24-Hour Time-Series Raw Data
XXX unique social accounts have posts mentioning Protagonist Therapeutics, Inc (PTGX) in the last XX hours which is down XX% from XXX in the previous XX hours Daily Average: XX
X Week: XXX -XXXX%
X Month: XXXXX -XX%
X Months: XXXXX +977%
X Year: XXXXX +1,229%
1-Year High: XXX on 2025-06-28
1-Year Low: X on 2025-01-28

The most influential creators that mention Protagonist Therapeutics, Inc in the last XX hours

Creator Rank Followers Posts Engagements
@art X XXXXXXX X XXXXX
@semodough X XXXXXX X XXXXX
@Biotech2k1 X XXXXXX XX XXX
@yodaez X XXXXXX X XXX
@doepke_michel X XXXXX X XXX
@protocolrecordings X XXXXXXX X XXX
@AponiaAnalytics X XXXXX X XX
@seedytx19 X XXXXX X XX
@ChartMill X XXXXXX X XX
@rezfszubagoly XX XXX X XX

View More

Sentiment: XX%

Sentiment Line Chart
Sentiment 24-Hour Time-Series Raw Data
Current Value: XX%
Daily Average: XX%
X Week: XX% +7%
X Month: XX% +4%
X Months: XX% -XX%
X Year: XX% -XX%
1-Year High: XXX% on 2024-12-11
1-Year Low: XX% on 2025-01-01

Most Supportive Themes:

  • Positive Clinical Trial Results: (40%) Protagonist Therapeutics announced positive clinical trial results for icotrokinra, a novel peptide-based therapeutic for psoriasis.
  • Increased Trading Volume and Social Activity: (35%) Significant increases in trading volume, social dominance, and engagements indicate heightened market interest and community interaction.
  • Analyst Recommendations and Price Targets: (15%) Analyst ratings and price targets suggest potential upside, contributing to positive sentiment and investor confidence.

Most Critical Themes:

  • Market Volatility and General Market Sentiment: (10%) Overall market sentiment is neutral, with some discussions acknowledging general market volatility.

Social Dominance: XXXXX%

Social Dominance Line Chart
Social Dominance 24-Hour Time-Series Raw Data
Current Value: XXXXX%
Daily Average: XXXXX%
X Week: XXXXX% +0.0054%
X Month: XXXXX% +0.058%
X Months: XXXXX% +0.082%
X Year: XXXXX% +0.082%
1-Year High: XXXXX% on 2025-12-10
1-Year Low: XXXXX% on 2025-09-07

Market Dominance: XXXXXXX%

Market Dominance Line Chart
Market Dominance 24-Hour Time-Series Raw Data
Current Value: XXXXXXX%
Daily Average: X%
1-Year High: XXXXX% on 2025-03-31
1-Year Low: XXXXXXX% on 2025-02-27

Market Cap: $XXXXXXXXXXXXX

Market Cap Line Chart
Market Cap 24-Hour Time-Series Raw Data
Current Value: $XXXXXXXXXXXXX
Daily Average: $XXXXXXXXXXXXX
X Week: $XXXXXXXXXXXXX +$4.80%
X Month: $XXXXXXXXXXXXX +$12%
X Months: $XXXXXXXXXXXXX +$59%
1-Year High: $XXXXXXXXXXXXX on 2025-12-08
1-Year Low: $XXXXXXXXXXXXX on 2025-02-27

Top Protagonist Therapeutics, Inc Social Posts

Top posts by engagements in the last XX hours

Showing only X posts for non-authenticated requests. Use your API key in requests for full results.

"214 high prot low carb low cal huge dinner bowl"
Reddit Link @seven_1312 2025-12-09T21:24Z X followers, XX engagements

"@TalonFey7 @AdinHaykin1 This is not from the Roman Catholic Church. This is the Orthodox Church Canon law and the apostolic canons which predate the Bible. Wake up silly prot. Youre in a cult"
X Link @wrightwingman 2025-12-09T14:46Z 2115 followers, XXX engagements

"wts lfb blackpink ph Up Blackpink funko pop pink venom X pack (Hot topic exclusive) Repriced from 3700 + XXX for the protector "to 2950" - price : 2950 w/ prot na *See alt T. Deadline blackpink blink jennie lisa jisoo ros shutdown collector collection figure born pink"
X Link @zashikko 2025-12-09T04:40Z XXX followers, XXX engagements

"🎢🎡 "Interplanetarian (The Ride Home Remix) 🎢🎡"
YouTube Link @toyboxnostalgia 2025-12-08T22:01Z 1510 followers, XX engagements

Protagonist Therapeutics, Inc (PTGX)
/topic/$ptgx