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![NeuroscienceNew Avatar](https://lunarcrush.com/gi/w:24/cr:twitter::32302688.png) Neuroscience News [@NeuroscienceNew](/creator/twitter/NeuroscienceNew) on x 504.5K followers
Created: 2025-07-23 19:17:35 UTC

“Neurobiotic Sense” Tells Brain When You’ve Had Enough

Researchers have identified a new “neurobiotic sense,” showing how the gut directly signals the brain to help control appetite. 

Specialized cells in the colon, called neuropods, detect a microbial protein called flagellin and send messages through the vagus nerve. 

In mice, this signal suppressed eating, but disrupting the pathway caused overeating and weight gain. 

The findings reveal a real-time connection between gut microbes and behavior, beyond immune and inflammatory responses. 

This discovery may also shed light on how diet and microbiota influence mood and health. 

Future research could explore how altering gut microbes might treat obesity and psychiatric conditions.

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**Related Topics**
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