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![BowTiedBiotech Avatar](https://lunarcrush.com/gi/w:24/cr:twitter::1462941795520638981.png) BowTiedBiotech 🧪🔬🧬 [@BowTiedBiotech](/creator/twitter/BowTiedBiotech) on x 19.7K followers
Created: 2025-07-22 22:54:55 UTC

RIP @Sports_bios IYKYK

This is $ABVX obefazimod ABTECT Ph3 induction readout – XX mg QD meets FDA CR @ wk-8 w/ ∆19.3 % (105) & XXXX % (106) – all key 2° (endo-imp, clin-resp, HEMI-1) stat-sig – caveat: XX mg misses CR in XXX but pooled clin-resp ∆28.6 % – trial ~47 % adv-Tx exp incl biggest JAK-fail pop ever in UC Ph3 – safety looks clean, TEAE-d/c ≤5 %, no new sigs – 678/1,275 responders roll into XX wk maint (readout 2Q26) – resp-only maint design so need ≥40 % CR to lock best-in-class oral – cash ≈€61 M so expect raise or BD pre-NDA – jmho


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[Post Link](https://x.com/BowTiedBiotech/status/1947792502066417706)