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![NeuroscienceNew Avatar](https://lunarcrush.com/gi/w:24/cr:twitter::32302688.png) Neuroscience News [@NeuroscienceNew](/creator/twitter/NeuroscienceNew) on x 504.4K followers
Created: 2025-07-17 21:43:40 UTC

Neurons Store Backup Energy to Power the Brain Under Stress

Neurons have long been thought to depend entirely on support cells for their energy needs. 

However, a new study shows neurons store their own glycogen, acting as emergency fuel during metabolic stress. 

Using C. elegans worms and advanced biosensors, researchers discovered neurons activate glycogen reserves when oxygen is low or mitochondria are impaired. 

This backup system, called “glycogen-dependent glycolytic plasticity,” helps neurons stay functional under adverse conditions. 

The findings reshape the understanding of how the brain fuels itself. 

They also point to potential strategies for protecting neurons in stroke and neurodegenerative diseases.

![](https://pbs.twimg.com/media/GwFyq7HX0AALPGR.jpg)

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