[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]  Neuroscience News [@NeuroscienceNew](/creator/twitter/NeuroscienceNew) on x 504.1K followers Created: 2025-07-08 20:35:11 UTC Later-Born Neurons Mature Faster to Keep Networks in Balance The brain’s balance between excitatory and inhibitory neurons is vital for healthy function, yet how this balance is maintained during development was unclear. New research shows that inhibitory neurons born later mature more quickly than earlier ones, ensuring they are ready to integrate into neural circuits on time. This catch-up process is driven by changes in the chromatin landscape, which alters DNA accessibility and gene expression in precursor cells. Without this adjustment, neural networks risk imbalance, with some neurons forming too many or too few connections. The findings also reveal how mutations in these processes could contribute to disorders like autism or epilepsy. Understanding these timing mechanisms could help explain differences in brain development across species.  XXXXX engagements  **Related Topics** [neural](/topic/neural) [brains](/topic/brains) [Post Link](https://x.com/NeuroscienceNew/status/1942683909080150100)
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Neuroscience News @NeuroscienceNew on x 504.1K followers
Created: 2025-07-08 20:35:11 UTC
Later-Born Neurons Mature Faster to Keep Networks in Balance
The brain’s balance between excitatory and inhibitory neurons is vital for healthy function, yet how this balance is maintained during development was unclear.
New research shows that inhibitory neurons born later mature more quickly than earlier ones, ensuring they are ready to integrate into neural circuits on time.
This catch-up process is driven by changes in the chromatin landscape, which alters DNA accessibility and gene expression in precursor cells.
Without this adjustment, neural networks risk imbalance, with some neurons forming too many or too few connections.
The findings also reveal how mutations in these processes could contribute to disorders like autism or epilepsy.
Understanding these timing mechanisms could help explain differences in brain development across species.
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