[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]  Neuroscience News [@NeuroscienceNew](/creator/twitter/NeuroscienceNew) on x 504.1K followers Created: 2025-07-02 20:40:46 UTC Brain Taps Lipid Stores for Energy During Activity Contrary to long-held assumptions, neurons can break down fat for energy when glucose is in short supply. In a new study, researchers found that lipid droplets inside neurons are activated by synaptic electrical activity and metabolized into fatty acids that fuel mitochondria. This fat-burning process is controlled by the brain's activity level—more active neurons burn more fat. Disrupting the pathway that transports fatty acids into mitochondria led to a torpor-like state in mice, highlighting its biological importance. The findings challenge the view that fat metabolism is irrelevant to brain function. They also suggest new avenues for understanding neurodegenerative diseases that involve disrupted energy metabolism.  XXXXXX engagements  **Related Topics** [brains](/topic/brains) [coins energy](/topic/coins-energy) [Post Link](https://x.com/NeuroscienceNew/status/1940510987352002968)
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Neuroscience News @NeuroscienceNew on x 504.1K followers
Created: 2025-07-02 20:40:46 UTC
Brain Taps Lipid Stores for Energy During Activity
Contrary to long-held assumptions, neurons can break down fat for energy when glucose is in short supply.
In a new study, researchers found that lipid droplets inside neurons are activated by synaptic electrical activity and metabolized into fatty acids that fuel mitochondria.
This fat-burning process is controlled by the brain's activity level—more active neurons burn more fat.
Disrupting the pathway that transports fatty acids into mitochondria led to a torpor-like state in mice, highlighting its biological importance.
The findings challenge the view that fat metabolism is irrelevant to brain function.
They also suggest new avenues for understanding neurodegenerative diseases that involve disrupted energy metabolism.
XXXXXX engagements
Related Topics brains coins energy