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![BowTiedBiotech Avatar](https://lunarcrush.com/gi/w:24/cr:twitter::1462941795520638981.png) BowTiedBiotech 🧪🔬🧬 [@BowTiedBiotech](/creator/twitter/BowTiedBiotech) on x 19.7K followers
Created: 2025-05-22 11:43:00 UTC

🔸 The Asset: SSGJ-707

3SBio’s PD-1 x VEGF bispecific is showing strong data:

👉🏼 XX% ORR, XXX% DCR as monotherapy in 1L PD-L1+ NSCLC

👉🏼 XX% ORR in squamous NSCLC combo

👉🏼 XX% ORR in ≥3L mCRC

🧐Pfizer’s likely plan? Combine it with MMAE-based ADCs like Padcev to drive real differentiation.

👷And critically: manufacturing will happen in the U.S.

Sanford, NC (drug substance)
McPherson, KS (drug product)

![](https://pbs.twimg.com/media/GrjQMEeXwAA6pK4.jpg)

XXXXX engagements

![Engagements Line Chart](https://lunarcrush.com/gi/w:600/p:tweet::1925517750169899273/c:line.svg)

**Related Topics**
[combo](/topic/combo)

[Post Link](https://x.com/BowTiedBiotech/status/1925517750169899273)