#  @robinwjsia Robin Sia Robin Sia posts on X about ibm, copd, glp1, lithium the most. They currently have [---] followers and [---] posts still getting attention that total [------] engagements in the last [--] hours. ### Engagements: [------] [#](/creator/twitter::1488268922680131584/interactions)  - [--] Week [------] +481% - [--] Month [------] +8,031% - [--] Months [------] +7,228% - [--] Year [------] +3,226% ### Mentions: [--] [#](/creator/twitter::1488268922680131584/posts_active)  ### Followers: [---] [#](/creator/twitter::1488268922680131584/followers)  - [--] Week [---] +52% - [--] Month [---] +110% - [--] Months [---] +144% - [--] Year [---] +222% ### CreatorRank: [---------] [#](/creator/twitter::1488268922680131584/influencer_rank)  ### Social Influence **Social category influence** [currencies](/list/currencies) [finance](/list/finance) [stocks](/list/stocks) [technology brands](/list/technology-brands) **Social topic influence** [ibm](/topic/ibm), [copd](/topic/copd), [glp1](/topic/glp1), [lithium](/topic/lithium), [rifampicin](/topic/rifampicin), [aion](/topic/aion), [weight loss](/topic/weight-loss), [pfizer](/topic/pfizer), [tac](/topic/tac), [enzyme](/topic/enzyme) **Top assets mentioned** [IBM (IBM)](/topic/ibm) [GLP1 (GLP1)](/topic/glp1) [Lithium (LITH)](/topic/lithium) [Rifampicin (RIF)](/topic/rifampicin) [Pfizer, Inc. (PFE)](/topic/pfizer) [Enzyme (MLN)](/topic/enzyme) [Neuron (NRN)](/topic/neuron) [Waves (WAVES)](/topic/waves) ### Top Social Posts Top posts by engagements in the last [--] hours "Acute disease ie GN pulse steroids + MMF/CYC. Can trial CNI/Ritux" [X Link](https://x.com/robinwjsia/status/1702687485355258111) 2023-09-15T14:15Z [---] followers, [--] engagements "Associated with APLS - If have SLE and APLS with thrombotic event will likely require VKOA lifelong with target INR [---] 3.5" [X Link](https://x.com/robinwjsia/status/1702687487095886086) 2023-09-15T14:15Z [---] followers, [--] engagements "OSA: Menopause Craniofacial abnormalities Mallampati score MVA metabolic risk pulmonary HTN Nocturnal bradyarrhythmia most common arrhythmia from OSA STOPBANG Questionaire OSA50 score" [X Link](https://x.com/robinwjsia/status/1746425841385721943) 2024-01-14T06:55Z [---] followers, [--] engagements "OSA: STOPBANG Questionaire OSA50 score Weight loss avoid meds (BZD worsen and opioids) Mouth guards CPAP Uvulopalatopharyngioplasty Positional therapy (to avoid lying supine) 65% adherent to CPAP by [--] years Poor adherence - [--] hrs per night of CPAP" [X Link](https://x.com/robinwjsia/status/1746425843499643065) 2024-01-14T06:55Z [---] followers, [--] engagements "Steroids does not reduce mortality in COPD" [X Link](https://x.com/robinwjsia/status/1783073513886339467) 2024-04-24T10:00Z [---] followers, [--] engagements "A discussion at dinner recently held by @pfizer who sponsors XELJANZ (Tofacitinib): SEMAPHORE trial (2022) - use of Actemra (Tocilizumab) in PMR. It's still up in the air but trials are promising to reduce PNL burden although duration remains unclear" [X Link](https://x.com/robinwjsia/status/1825109107256566241) 2024-08-18T09:54Z [---] followers, [--] engagements "Treatment depends on organ manifestation: - Hydroxychloroquine remains cornerstone (and safe for pregnancy) - MMF CYC for renal involvement - CNI (TAC and CsA) good adjunct without haematological complications - RTX and Belimumab Anifrolumab as further treatment" [X Link](https://x.com/robinwjsia/status/1847798129422381338) 2024-10-20T00:32Z [---] followers, [--] engagements "- IV CYC for CNS involvement and severe lupus nephritis - MTX and AZA can also be considered as steroid sparing agents Aspirin for APLS. Warfarin for thrombosis (INR 2-3 3-4 if arterial thrombosis)" [X Link](https://x.com/robinwjsia/status/1847798131662229986) 2024-10-20T00:32Z [---] followers, [--] engagements "VEXAS syndrome 🩸: V - Vacuolisation of cells E - E1 ubiquitin enzyme encoded by UBA1 gene X- Found on X chromosome A - Autoinflammation S - Somatic mutation (not inherited) #MedX #rheumatology" [X Link](https://x.com/robinwjsia/status/1860635854810796401) 2024-11-24T10:45Z [---] followers, [--] engagements "SUMMIT trial - GLP1 for improvement in cardiac health. A new era of GLP1 taking over SGLT2i https://pubmed.ncbi.nlm.nih.gov/39566869/ https://pubmed.ncbi.nlm.nih.gov/39566869/" [X Link](https://x.com/robinwjsia/status/1860637551088025634) 2024-11-24T10:52Z [---] followers, [--] engagements "A relatively new ECG waveform: Bundgaard syndrome: Unexplained concave-upward ST depression in at least [--] leads 90ms after J point ST elevation in lead aVR 0.1mV ECG findings are persistent with time Autosomal dominant pattern of inheritance Source: LITFL #MedX" [X Link](https://x.com/robinwjsia/status/1860638398480052632) 2024-11-24T10:55Z [---] followers, [--] engagements "Differentials for immune-mediated inner ear disease (IMIED): Cogan syndrome Susac syndrome Vogt-Koyanagi-Harada syndrome AAV Behcets Sarcoidosis RP SLE/APLS Sjogtens RA IBD KID (keratosis ichthyosis deafness) syndrome Syphilis Lymphoma Whipples" [X Link](https://x.com/robinwjsia/status/1861175648045380042) 2024-11-25T22:30Z [---] followers, [--] engagements "@OGdukeneurosurg C- motor neuron disease (MND) with mix of pure motor deficit (both UMNL and LMNL) D - length dependent peripheral neuropathy including AIDP CIDP and other GBS-variants" [X Link](https://x.com/robinwjsia/status/1863326163009188036) 2024-12-01T20:55Z [---] followers, [---] engagements "EBV - EBV Viral capsid antigen (VCA) - IgG IgM - EBNA (6-12 weeks after onset positive lifelong)" [X Link](https://x.com/robinwjsia/status/1865581144261144589) 2024-12-08T02:16Z [---] followers, [--] engagements "Drugs that can cause serotonin syndrome: 1) Reduce breakdown - MAOI abx (linezolid) 2) Decrease uptake - SSRI SNRI TCA opioids anti-seizures anti-emetics 3) Increased agonist - lithium 4) Increased release - amphetamines cocaine" [X Link](https://x.com/robinwjsia/status/1868045577977741371) 2024-12-14T21:29Z [---] followers, [--] engagements "5 mechanism for serotonin syndrome: 1) Decreased breakdown - MAOI abx (linezolid) 2) Decreased reuptake - SSRI SNRI TCA Opioids Antiepileptics Antiemetics 3) Increased agonist - Lithium fentanyl 4) Increased release - stimulants anorectics drugs of abuse 5) CYP2D6 and CYP3A4 inh" [X Link](https://x.com/robinwjsia/status/1868553794138874117) 2024-12-16T07:08Z [---] followers, [--] engagements "AST and ALT: AST: liver skeletal and cardiac muscle kidney and brain AST mostly in mitochonrial (mAST) 80% and the rest in cytoplasmic (cAST) There's more AST than ALT but half life shorter 18hr vs 36hrs for ALT makes the ratio 1:1" [X Link](https://x.com/robinwjsia/status/1868575794953646461) 2024-12-16T08:36Z [---] followers, [--] engagements "In cirrhosis: ASTALT - reduced sinusoidal clearance of AST in EtOH B6 reduces production of ALT Also mitochondrial damage causing higher AST release" [X Link](https://x.com/robinwjsia/status/1868575797143109998) 2024-12-16T08:36Z [---] followers, [--] engagements "Functions & lesions of different brain lobes: #MedX #MedTwitter #Neurology Frontal lobe - motor - personality - primitive reflexes - expressive dysphasia - anosmia - optic nerve compression - gait apraxia" [X Link](https://x.com/robinwjsia/status/1868589178805780856) 2024-12-16T09:29Z [---] followers, [--] engagements "Parietal lobe - sensory cortex - Gerstmann syndrome - inf quadrantanopia - construction/dressing apraxia - spatial" [X Link](https://x.com/robinwjsia/status/1868589180714115191) 2024-12-16T09:29Z [---] followers, [--] engagements "Classical pathway for complement - C4 C1 C2 Alternative pathway - C3 Factor H IBD and Properdin. Low C3 and C4 - post-strep SLE Low C3 only - MPGN Low C4 only - SLE" [X Link](https://x.com/robinwjsia/status/1870386433758040092) 2024-12-21T08:30Z [---] followers, [--] engagements "Increased TLCO: - Pulmonary haemorrhage - Asthma - L to R shunt Reduced TLCO: - ILD - COPD - Lung resection - pHTN - Anaemia - NM Weakness" [X Link](https://x.com/robinwjsia/status/1870391850068308295) 2024-12-21T08:52Z [---] followers, [--] engagements "CYP inducers: - Quinidine - Barbiturates - St Johns Wart - Phen - Nevirapine - Rifampicin - Griseofulvin - Carbamazepine - Chronic Alcohol - Glucocorticoids" [X Link](https://x.com/robinwjsia/status/1870394866481705325) 2024-12-21T09:04Z [---] followers, [--] engagements "P-gp - Inducers- St Johns Wart Rifampicin - Substrates - Atorvastatin Tacrolimus Dabigatran Rivaroxaban Losartan Digoxin - Inhibitor - Verapamil Amiodarone Ketoconazole Ritonavir Tacrolimus" [X Link](https://x.com/robinwjsia/status/1870398051816521953) 2024-12-21T09:17Z [---] followers, [--] engagements "Haemolysis can be divided to extravascular or intravascular:" [X Link](https://x.com/robinwjsia/status/1872575376750415927) 2024-12-27T09:28Z [---] followers, [--] engagements "Extravascular (outside of vessels) - Intracorpuscular - RBC defects haemoglobinopathies enzyme deficiencies - extracorpuscular - hypersplenism" [X Link](https://x.com/robinwjsia/status/1872575379556458909) 2024-12-27T09:28Z [---] followers, [--] engagements "JVP: - a wave- atrial contraction - c wave - closure of tricuspid valve - x wave- atrial relaxation - v wave - ventricular contraction - y wave - ventricular emptying" [X Link](https://x.com/robinwjsia/status/1874304442285383897) 2025-01-01T03:59Z [---] followers, [--] engagements "@MayoClinicINFD Gram negative diplococci of neiserria gonorrhoeae. Can cause reactive arthritis or sometimes Reiter's syndrome (urethritis/epididymitis tenosynovitis/enthesitis/synovitis uveitis) PID (Fitz-Hugh-Curtis Syndrome) - rare" [X Link](https://x.com/robinwjsia/status/1875872046061891627) 2025-01-05T11:48Z [---] followers, [---] engagements "DPP4i causes physiological GLP1 levels and elevated incretin which acts on alpha cells" [X Link](https://x.com/robinwjsia/status/1879105654935392312) 2025-01-14T09:57Z [---] followers, [--] engagements "Non-invasive ventilation - only proven for COPD and acute pulmonary edema" [X Link](https://x.com/robinwjsia/status/1880864193802559545) 2025-01-19T06:25Z [---] followers, [--] engagements "Odds ratio - ratio of exposure in cases to ratio of exposure in control" [X Link](https://x.com/robinwjsia/status/1901596923540258898) 2025-03-17T11:30Z [---] followers, [--] engagements "Goodpasture's syndrome is associated with anti-alpha3 chain of type IV collagen" [X Link](https://x.com/robinwjsia/status/1903597091764805752) 2025-03-22T23:58Z [---] followers, [--] engagements "P-gp substrates: Atorvastatin Tacrolimus Dabigatran Rivaroxaban losartan digoxin P-gp inhibitors: Verapamil amiodarone ketoconazole ritonavir tacrolimus. P-gp inducers - Rifampicin St John's Wart" [X Link](https://x.com/robinwjsia/status/1907375623049502936) 2025-04-02T10:12Z [---] followers, [--] engagements "Pulmonary artery hypertension is related to endothelin A and B causing vasoconstriction" [X Link](https://x.com/robinwjsia/status/1908435996682969429) 2025-04-05T08:26Z [---] followers, [--] engagements "Classes of antibiotics: 1) Cell wall synthesis inhibitor - Fosfomycin - Beta-lactams (Cephalosporins penicillin carbapenems monobactam) - Glycopeptides (Vancomycin teicoplanin) - Lipopeptides - Daptomycin" [X Link](https://x.com/robinwjsia/status/1908662883497762878) 2025-04-05T23:27Z [---] followers, [--] engagements "2) DNA synthesis inhibitor - Nitroimidazoles - Metronidazole - Fluoroquinolones - Ciprofloxacin 3) RNA synthesis inhibitor - Rifampicin 4) Ribosome inhibitors - Nitrofurantoin - Oxazolidinones (linezolid) - macrolides - azithro clarithromycin - lincosamides - clindamycin - tetracycline - doxycycline - aminoglycosides - gentamicin 5) metabolite inhibitors - folate antagonist - TMP/SMX" [X Link](https://x.com/robinwjsia/status/1908662885339083181) 2025-04-05T23:27Z [---] followers, [--] engagements "MecA gene in MRSA leads to PBP2A (less affinity to beta-lactams)" [X Link](https://x.com/robinwjsia/status/1908768607997469171) 2025-04-06T06:27Z [---] followers, [--] engagements "Incretin cells - from L and K cells - GLP1/GIP works on this - DPP4 destroys incretins" [X Link](https://x.com/robinwjsia/status/1909196721344905237) 2025-04-07T10:49Z [---] followers, [--] engagements "Types of FTD: - Behavioural - Semantin - Primary progressive aphasia - Non-motor" [X Link](https://x.com/robinwjsia/status/1909706546793337147) 2025-04-08T20:34Z [---] followers, [--] engagements "Bohr effect - acidity - oxygens binds less well to Hb. Haldane effect - High O2 CO2 binds less well to Hb facilitating release in lungs" [X Link](https://x.com/robinwjsia/status/1910983585970176174) 2025-04-12T09:09Z [---] followers, [--] engagements "Interferon-gamma release assay detects T-cell responses to ESAT-6 and CFP-10 antigens which are absent in most non-tuberculous mycobacteria but are expressed by a few species such as M. kansasii and M. marinum leading to rare false-positive results" [X Link](https://x.com/robinwjsia/status/1911327644156825872) 2025-04-13T07:56Z [---] followers, [--] engagements "So what's the difference between SS and NMS - NMS is usually after days to weeks - NMS is caused by DA withdrawal and overdose - NMS has BRADYreflexia and enhanced rigidity without NM excitation Criteria for SS - Hunter and Sternbach" [X Link](https://x.com/robinwjsia/status/1925806581133771167) 2025-05-23T06:50Z [---] followers, [--] engagements "Treatment: BZD Non-serotonergic antiemetics Severe (Severe hyperthermia and hypoventilation from rigidity) - cyproheptadine and chlorpramazine WH SSRI (Sertraline washout of [--] weeks fluoxetine washout of [--] weeks)" [X Link](https://x.com/robinwjsia/status/1925806583272902744) 2025-05-23T06:50Z [---] followers, [--] engagements "SLC3A9 gene determines TPMT enzyme function" [X Link](https://x.com/robinwjsia/status/1926288521754476923) 2025-05-24T14:45Z [---] followers, [--] engagements "KLRG1 on highly differentiated T cells are one of the main pathophysiology for IBM" [X Link](https://x.com/robinwjsia/status/1936338121538650517) 2025-06-21T08:19Z [---] followers, [--] engagements "Pain is interpretered at the somatosensory cortex via spinothalamic fibres" [X Link](https://x.com/robinwjsia/status/1936560014396944397) 2025-06-21T23:01Z [---] followers, [---] engagements "JVP waves: - a wave - atrial contraction - c wave - closure of tricuspid valve - x wave - atrial relaxation - v wave - volume filling - y wave - atrial emptying into ventricles" [X Link](https://x.com/robinwjsia/status/1939135016161944054) 2025-06-29T01:33Z [---] followers, [--] engagements "Alzheimer's finding in FDG-PET - loss of temporo-parietal cortex and posterior cingulate cortex (as opposed to anterior cingulate cortex for FTD)" [X Link](https://x.com/robinwjsia/status/1939167191104192558) 2025-06-29T03:41Z [---] followers, [--] engagements "Targeting TRVB9 in AxS Exciting https://pubmed.ncbi.nlm.nih.gov/37872223/ https://pubmed.ncbi.nlm.nih.gov/37872223/" [X Link](https://x.com/robinwjsia/status/1939223486465241339) 2025-06-29T07:24Z [---] followers, [--] engagements "Choice of management for APLS - arterial requires antiplatelet and venous usually anticoagulant but often can be trickier. HCQ in only sAPLS ie in pt with SLE #APLAR25 #APLAR" [X Link](https://x.com/robinwjsia/status/1964599911699403113) 2025-09-07T08:01Z [---] followers, [---] engagements "Serum IgG4 5x ULN has PPV of 75% for IgG4RD" [X Link](https://x.com/robinwjsia/status/1966096115138453654) 2025-09-11T11:06Z [---] followers, [---] engagements "Central to problem representation is: 1) Who is the patient 2) What is the tempo 3) Is there a syndrome" [X Link](https://x.com/robinwjsia/status/1967177861800006052) 2025-09-14T10:45Z [---] followers, [--] engagements "Cocaine is a crystalline alkaloid from cocoa plants with its content of 70% levamisole which is used to cut cocaine - it is a antihelminth agent and previously used for RA and CRC but off the market due to risk of agranulocytosis" [X Link](https://x.com/robinwjsia/status/1972933082597785762) 2025-09-30T07:54Z [---] followers, [--] engagements "GLP1 comes from L cells and GIP comes from K cells in the SI" [X Link](https://x.com/robinwjsia/status/1890729559336575358) 2025-02-15T11:47Z [---] followers, [--] engagements "@modernHealthMe Hyperk" [X Link](https://x.com/robinwjsia/status/1922035657729269982) 2025-05-12T21:06Z [---] followers, [----] engagements "4H and 4Ts of PEA: - Hypoxia - Hypovolemia - Hypothermia - Hypo/hyperK - Thrombosis (Coronary & Pulmonary) - Tamponade - Tension pneumothorax - Toxins" [X Link](https://x.com/robinwjsia/status/1926457974202978424) 2025-05-25T01:59Z [---] followers, [--] engagements "@simplify_drugs Hyperk as it inhibits RAAS" [X Link](https://x.com/robinwjsia/status/1936259390073717049) 2025-06-21T03:06Z [---] followers, [---] engagements "4H and Ts of PEA: - hypoxia hypovolemia hypothermia and hypo/hyperK - thrombus tension pneumothorax toxin and tamponade" [X Link](https://x.com/robinwjsia/status/1947630176571167187) 2025-07-22T12:09Z [---] followers, [--] engagements "HLADRB1*11:01 is associated with statin induced myositis" [X Link](https://x.com/robinwjsia/status/1967008016693404149) 2025-09-13T23:30Z [---] followers, [---] engagements "RTX and TCZ are the best options for patients with ILD with CTD" [X Link](https://x.com/robinwjsia/status/1977344410950975556) 2025-10-12T12:03Z [---] followers, [---] engagements "Causes of cardiac mass: 1) Thrombus 2) Vegetations (endocarditis) 3) Benign masses - atrial myxoma papillary fibroelastoma lipoma rhabdomyoma 4) Malignant masses - angiosarcoma rhabdomyosarcoma metastases (lung breast kidney melanoma) 5) Cardiac lymphoma Definity TTE PET transcutaneous catheter with biopsy could be useful. https://twitter.com/i/web/status/1989852785236676892 https://twitter.com/i/web/status/1989852785236676892" [X Link](https://x.com/robinwjsia/status/1989852785236676892) 2025-11-16T00:27Z [---] followers, [--] engagements "Classes of antihistamines: 1st gen - chlorphenamine promethazine and diphenhydramine 2nd gen - loratidine ceterizine and fexofenadine" [X Link](https://x.com/robinwjsia/status/1989873629627388416) 2025-11-16T01:50Z [---] followers, [--] engagements "HSV encephalitis tends to affect medial temporal orbitofrontal and insular cortex" [X Link](https://x.com/robinwjsia/status/1991980467294441621) 2025-11-21T21:22Z [---] followers, [--] engagements "Babinski-negotte syndrome is associated with mixed medial and lateral medullary syndromes ie involvement of sympathetic pathway + Wallenberg syndrome" [X Link](https://x.com/robinwjsia/status/2003951009060868566) 2025-12-24T22:08Z [---] followers, [--] engagements "@MTD_MED @IhabFathiSulima Lamotrigine is the most common cause of SJS/TENS among AEDs although genotype HLAB1502 carries the risk for CMZ" [X Link](https://x.com/robinwjsia/status/2004370154919285162) 2025-12-26T01:54Z [---] followers, [----] engagements "@hemo_shk @IhabFathiSulima En coup de sabre a form of Morphea" [X Link](https://x.com/robinwjsia/status/2007037147422031919) 2026-01-02T10:31Z [---] followers, [---] engagements "@DrMedica_13 Fe def with angular stomatitis" [X Link](https://x.com/robinwjsia/status/2012285932234490053) 2026-01-16T22:08Z [---] followers, [--] engagements "Gout can present with occular manifestations ie scleritis scleral tophii and other red eye symptoms" [X Link](https://x.com/robinwjsia/status/2012464637476778204) 2026-01-17T09:58Z [---] followers, [--] engagements "@knowmedge Colchicine Followed by AZA IL-1 and IVIg" [X Link](https://x.com/robinwjsia/status/2014864371319767128) 2026-01-24T00:54Z [---] followers, [---] engagements "@DrAkhilX @BJSurgery Thomas sign of malignancy at ampulla of vater" [X Link](https://x.com/robinwjsia/status/2022427761315582262) 2026-02-13T21:48Z [---] followers, [----] engagements "Pizotifen (used in migraine prophylaxis) can cause weight gain" [X Link](https://x.com/robinwjsia/status/1611646187719000066) 2023-01-07T08:49Z [---] followers, [---] engagements "Low albumin can cause a falsely low anion gap" [X Link](https://x.com/robinwjsia/status/2016451939509362718) 2026-01-28T10:03Z [---] followers, [---] engagements "Class III and IV lupus nephritis are the window to aggressive treatment albeit with MMF vs AZA CNI Belimumab +/- Ritux HCQ and RAASi" [X Link](https://x.com/robinwjsia/status/2016840070393975102) 2026-01-29T11:45Z [---] followers, [---] engagements "Although in RAVE trial the use of rituximab in induction of AAV did not include patients with severe renal impairment the RITUXVAS trial has proven that it is in fact non-inferior to CYC or AZA in induction. Furthermore MAINRITSAN trials prove RTX to be a fantastic drug for maintenance in AAV (mainly GPA and MPA) #Rheumatology #MedX https://twitter.com/i/web/status/2017498823686557994 https://twitter.com/i/web/status/2017498823686557994" [X Link](https://x.com/robinwjsia/status/2017498823686557994) 2026-01-31T07:22Z [---] followers, [---] engagements "Migratory oligoarthritis: Gonococcal Rheumatic fever SLE AAV (especially GPA)" [X Link](https://x.com/robinwjsia/status/2018046463327277244) 2026-02-01T19:39Z [---] followers, [---] engagements "HIV testing can be falsely negative within the [--] days of acquisition" [X Link](https://x.com/robinwjsia/status/2019497306282946572) 2026-02-05T19:44Z [---] followers, [---] engagements "B) LBD characterized by fluctuation in hallucinations mimicking delirium with lilliputian hallucinations. Often presents with motor symptoms approximately a year after. Minimal response to dopamine replacement/agonists trial of anti-acetylcholinesterase inhibitors recommended https://twitter.com/i/web/status/2020248677361795482 https://twitter.com/i/web/status/2020248677361795482" [X Link](https://x.com/robinwjsia/status/2020248677361795482) 2026-02-07T21:29Z [---] followers, [---] engagements "Tests for rotator cuff: - Hawkin's test (impingement) - Full can and empty can - supraspinatous - External rotation - infraspinatous - Lift off test or belly test - subscapularis - Hornblower test - teres minor" [X Link](https://x.com/robinwjsia/status/2020365911870566816) 2026-02-08T05:15Z [---] followers, [----] engagements "Tests for SIJ: - FABER test - Yeaman's test - Gaelan's test" [X Link](https://x.com/robinwjsia/status/2020365996226408595) 2026-02-08T05:16Z [---] followers, [----] engagements "Anti-Jo1 ASyS is associated with HLADRB1*03:01 whereas HMGCr Myositis is associated with HLADRB1*11:01" [X Link](https://x.com/robinwjsia/status/2020369421412483534) 2026-02-08T05:29Z [---] followers, [----] engagements "Polymyositis is now exceedingly rare with the absence if extramuscular manifestation and current data demonstrates it can be likely divided into IMNM ASyS and overlap myositis" [X Link](https://x.com/robinwjsia/status/2020369754922578192) 2026-02-08T05:31Z [---] followers, [---] engagements "IBM is unique in which it affects knee extensors and finger flexors" [X Link](https://x.com/robinwjsia/status/2020370093902086179) 2026-02-08T05:32Z [---] followers, [---] engagements "Secondary causes of Raynauds: - CTD - medications (beta-blockers amphetamine migraine meds IFN chemotherapy) - paraneoplastic - haematological ie cryoglobulin cold agglutinin" [X Link](https://x.com/robinwjsia/status/2020948393808495062) 2026-02-09T19:50Z [---] followers, [----] engagements "For treatment of Raynauds: - PDE5 is sildenafil - prostacyclin analogue ie Illoprost treprostenil - DHPCCB ie nifedipine For prevention of Raynauds; - endothelin antagonist ie bosentan - prostacyclin analogue ie Illoprost treprostenil - DHPCCB ie nifedipine" [X Link](https://x.com/robinwjsia/status/2020948887973003444) 2026-02-09T19:52Z [---] followers, [----] engagements "Using a 512Hz tuning fork: Rinne's test - Placed over mastoid process usually ACBC but if BCAC - Conductive hearing loss Confirming that with Weber test: - sound localizes to bad sidee in conductive HL and to the good side in SNHL" [X Link](https://x.com/robinwjsia/status/2021162507256135826) 2026-02-10T10:01Z [---] followers, [---] engagements "Flecainide and Ajmalline challenge test could be used to diagnose Brugada syndrome" [X Link](https://x.com/robinwjsia/status/2021303941883892108) 2026-02-10T19:23Z [---] followers, [---] engagements "Use of beta-blockers in phaeochromocytoma may lead to unopposed alpha-adrenergic stimulation" [X Link](https://x.com/robinwjsia/status/2021710241658982529) 2026-02-11T22:17Z [---] followers, [----] engagements "Approach to N&V: 1) Ask if it's related to a syndrome ie Headache SOB 2) Episodic ie triggered by food Consider sphincter obstruction 3) Continuous Severe - CNS Cardiac GI pathology - non-severe - consider metabolic causes ie drugs toxins electrolyte disturbances" [X Link](https://x.com/robinwjsia/status/2022428229597110614) 2026-02-13T21:50Z [---] followers, [----] engagements "Cancer risk in inflammatory myopathies: 1) High risk - TIF1gamma and NXP2 dysphagia cutaneous persistently high disease activity age40 onset 2) Medium risk - SAE HMGCR MI2 MDA5 male sex 3) Low risk - Jo-1 SRP cN1a(IBM) ILD arthropathy Raynaud's #Rheumatology #MedX" [X Link](https://x.com/anyuser/status/2022787649833177477) 2026-02-14T21:38Z [---] followers, [----] engagements "In glomerulonephritis: - Low C3 and C4 - Lupus nephritis - Low C4 - cryoglobulinaemia - Low C3 - MPGN and post-infectious GN" [X Link](https://x.com/robinwjsia/status/2020370946222354857) 2026-02-08T05:35Z [---] followers, 39.5K engagements "t814 - Burkitt lymphoma t1114 - Mantle cell lymphoma t14:18 - Follicular lymphoma" [X Link](https://x.com/robinwjsia/status/2021696074935685536) 2026-02-11T21:21Z [---] followers, [----] engagements "Opthalmic manifestations of GCA - AION - PION - CRAO - BRAO - Choroidal ischaemia" [X Link](https://x.com/anyuser/status/2022799883976216969) 2026-02-14T22:27Z [---] followers, [----] engagements "Among all inflammatory myopathies ASyS overlap myositis and IBM are most associated with gastrointestinal symptoms. Articular ASyS and overlap myositis. Cardiac ASyS and IMNM" [X Link](https://x.com/robinwjsia/status/2022839916296822806) 2026-02-15T01:06Z [---] followers, [---] engagements "What a wonderful experience at #ARANZRA24 . It was filled with so much learning and fantastic interactions Also a huge thank you to [--] very inspirational mentors of mine Dr Andrew Foote and Dr Mueed Mian for guiding me through my research projects. @AusRheum" [X Link](https://x.com/anyuser/status/1792816095117930796) 2024-05-21T07:14Z [---] followers, [----] engagements "OSA can cause right heart failure through cor pulmonale- however with time it can cause left heart failure too secondary to chronically high intrathoracic pressure sympathetic drive and afterload" [X Link](https://x.com/anyuser/status/2023123839618785697) 2026-02-15T19:54Z [---] followers, [---] engagements "Darier sign where mild trauma can induce erythema and itch can be found in urticaria pigmentosa or systemic mastocytosis" [X Link](https://x.com/anyuser/status/2023123580309880850) 2026-02-15T19:53Z [---] followers, [---] engagements "Testicular germ-cell tumour: - Seminomas - normal AFP sometimes high bHCG and LDH - Non-seminomas - high AFP and more commonly high bHCG and LDH" [X Link](https://x.com/anyuser/status/2022940934552588760) 2026-02-15T07:47Z [---] followers, [----] engagements "Ovoid palatal patch can be seen in TIF1gamma DM. https://scispace.com/pdf/ovoid-palatal-patch-in-dermatomyositis-a-novel-finding-5aqpn1nfwz.pdf https://scispace.com/pdf/ovoid-palatal-patch-in-dermatomyositis-a-novel-finding-5aqpn1nfwz.pdf" [X Link](https://x.com/anyuser/status/2022940487553105924) 2026-02-15T07:46Z [---] followers, [---] engagements "Among all inflammatory myopathies ASyS overlap myositis and IBM are most associated with gastrointestinal symptoms. Articular ASyS and overlap myositis. Cardiac ASyS and IMNM" [X Link](https://x.com/robinwjsia/status/2022839916296822806) 2026-02-15T01:06Z [---] followers, [---] engagements "Differentials for PMR: - seronegative RA - regional soft tissue rheumatism - subacromial bursitis or supraspinatous tendonitis - myeloma - myositis - drug-induced myopathy - parkinson's (coat-hanger) - central sensitization" [X Link](https://x.com/anyuser/status/2022801251793027416) 2026-02-14T22:32Z [---] followers, [---] engagements "Opthalmic manifestations of GCA - AION - PION - CRAO - BRAO - Choroidal ischaemia" [X Link](https://x.com/anyuser/status/2022799883976216969) 2026-02-14T22:27Z [---] followers, [----] engagements "4 subtypes of GCA - GCA with cranial symptoms - Symptoms of LVV ie limb claudication - Fever subtype - PMR with vasculitis on imaging" [X Link](https://x.com/anyuser/status/2022799611513995441) 2026-02-14T22:26Z [---] followers, [---] engagements "Giant cell arteritis (GCA) can involve any arteries including external carotid branches (temporal and occipital) opthalmic vertebral distal subclavian and axillary arteries thoracic aorta" [X Link](https://x.com/anyuser/status/2022789840702779791) 2026-02-14T21:47Z [---] followers, [----] engagements "Interstitial lung disease patterns: NSIP - bilateral GGO with fine reticulation and traction bronchiectasis lower lobe predominant and subpleural sparing UIP - honey combing traction bronchiectasis basal subpleural reticulation LIP - GGO with thin-walled cysts and interlobular septal thickening OP - Patchy consolidation reverse halo sign AIP - Rapidly progressive diffuse alveolar opacities #Rheumatology #Pulmonology #MedX" [X Link](https://x.com/anyuser/status/2022788447497486564) 2026-02-14T21:42Z [---] followers, [----] engagements "Cancer risk in inflammatory myopathies: 1) High risk - TIF1gamma and NXP2 dysphagia cutaneous persistently high disease activity age40 onset 2) Medium risk - SAE HMGCR MI2 MDA5 male sex 3) Low risk - Jo-1 SRP cN1a(IBM) ILD arthropathy Raynaud's #Rheumatology #MedX" [X Link](https://x.com/anyuser/status/2022787649833177477) 2026-02-14T21:38Z [---] followers, [----] engagements "Screening panel: - CT- neck thorax abdomen and pelvis - cervical screening - mammography - PSA - CA125 - pelvic/transvaginal ultrasonography - FOBT - nasoendoscopy - FDG-PET" [X Link](https://x.com/anyuser/status/2022787651896820172) 2026-02-14T21:38Z [---] followers, [---] engagements "Loading medications are sometimes used in medications with long half life" [X Link](https://x.com/anyuser/status/2022610093951643837) 2026-02-14T09:53Z [---] followers, [---] engagements "Ketamine can cause bladder dysfunction" [X Link](https://x.com/anyuser/status/2022609987005222960) 2026-02-14T09:52Z [---] followers, [---] engagements "Duchenne muscular dystrophy can sometimes lead to dilated cardiomyopathy" [X Link](https://x.com/anyuser/status/2022602704963719472) 2026-02-14T09:23Z [---] followers, [---] engagements "Topiramate causes renal calculi via alkalisation of urine and hypocitraturia" [X Link](https://x.com/anyuser/status/2022602351572549958) 2026-02-14T09:22Z [---] followers, [---] engagements "Avacopan can be used as induction for ANCA vasculitis" [X Link](https://x.com/anyuser/status/2022558879671099504) 2026-02-14T06:29Z [---] followers, [---] engagements "Pauci-immune RPGN is characteristic of ANCA vasculitis" [X Link](https://x.com/anyuser/status/2022556741788160089) 2026-02-14T06:21Z [---] followers, [---] engagements "10% of patients with ANCA vasculitis are seronegative" [X Link](https://x.com/anyuser/status/2022556155843875229) 2026-02-14T06:18Z [---] followers, [---] engagements "Classes of lupus nephritis: Class [--] - minimal mental Class [--] - mesangioproliferative Class [--] - focal proliferative Class [--] - diffuse proliferative Class [--] - membranous Class [--] - advanced sclerosing #nephrology #medX" [X Link](https://x.com/anyuser/status/2022473956079604119) 2026-02-14T00:52Z [---] followers, [----] engagements Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing
@robinwjsia Robin SiaRobin Sia posts on X about ibm, copd, glp1, lithium the most. They currently have [---] followers and [---] posts still getting attention that total [------] engagements in the last [--] hours.
Social category influence currencies finance stocks technology brands
Social topic influence ibm, copd, glp1, lithium, rifampicin, aion, weight loss, pfizer, tac, enzyme
Top assets mentioned IBM (IBM) GLP1 (GLP1) Lithium (LITH) Rifampicin (RIF) Pfizer, Inc. (PFE) Enzyme (MLN) Neuron (NRN) Waves (WAVES)
Top posts by engagements in the last [--] hours
"Acute disease ie GN pulse steroids + MMF/CYC. Can trial CNI/Ritux"
X Link 2023-09-15T14:15Z [---] followers, [--] engagements
"Associated with APLS - If have SLE and APLS with thrombotic event will likely require VKOA lifelong with target INR [---] 3.5"
X Link 2023-09-15T14:15Z [---] followers, [--] engagements
"OSA: Menopause Craniofacial abnormalities Mallampati score MVA metabolic risk pulmonary HTN Nocturnal bradyarrhythmia most common arrhythmia from OSA STOPBANG Questionaire OSA50 score"
X Link 2024-01-14T06:55Z [---] followers, [--] engagements
"OSA: STOPBANG Questionaire OSA50 score Weight loss avoid meds (BZD worsen and opioids) Mouth guards CPAP Uvulopalatopharyngioplasty Positional therapy (to avoid lying supine) 65% adherent to CPAP by [--] years Poor adherence - [--] hrs per night of CPAP"
X Link 2024-01-14T06:55Z [---] followers, [--] engagements
"Steroids does not reduce mortality in COPD"
X Link 2024-04-24T10:00Z [---] followers, [--] engagements
"A discussion at dinner recently held by @pfizer who sponsors XELJANZ (Tofacitinib): SEMAPHORE trial (2022) - use of Actemra (Tocilizumab) in PMR. It's still up in the air but trials are promising to reduce PNL burden although duration remains unclear"
X Link 2024-08-18T09:54Z [---] followers, [--] engagements
"Treatment depends on organ manifestation: - Hydroxychloroquine remains cornerstone (and safe for pregnancy) - MMF CYC for renal involvement - CNI (TAC and CsA) good adjunct without haematological complications - RTX and Belimumab Anifrolumab as further treatment"
X Link 2024-10-20T00:32Z [---] followers, [--] engagements
"- IV CYC for CNS involvement and severe lupus nephritis - MTX and AZA can also be considered as steroid sparing agents Aspirin for APLS. Warfarin for thrombosis (INR 2-3 3-4 if arterial thrombosis)"
X Link 2024-10-20T00:32Z [---] followers, [--] engagements
"VEXAS syndrome 🩸: V - Vacuolisation of cells E - E1 ubiquitin enzyme encoded by UBA1 gene X- Found on X chromosome A - Autoinflammation S - Somatic mutation (not inherited) #MedX #rheumatology"
X Link 2024-11-24T10:45Z [---] followers, [--] engagements
"SUMMIT trial - GLP1 for improvement in cardiac health. A new era of GLP1 taking over SGLT2i https://pubmed.ncbi.nlm.nih.gov/39566869/ https://pubmed.ncbi.nlm.nih.gov/39566869/"
X Link 2024-11-24T10:52Z [---] followers, [--] engagements
"A relatively new ECG waveform: Bundgaard syndrome: Unexplained concave-upward ST depression in at least [--] leads 90ms after J point ST elevation in lead aVR 0.1mV ECG findings are persistent with time Autosomal dominant pattern of inheritance Source: LITFL #MedX"
X Link 2024-11-24T10:55Z [---] followers, [--] engagements
"Differentials for immune-mediated inner ear disease (IMIED): Cogan syndrome Susac syndrome Vogt-Koyanagi-Harada syndrome AAV Behcets Sarcoidosis RP SLE/APLS Sjogtens RA IBD KID (keratosis ichthyosis deafness) syndrome Syphilis Lymphoma Whipples"
X Link 2024-11-25T22:30Z [---] followers, [--] engagements
"@OGdukeneurosurg C- motor neuron disease (MND) with mix of pure motor deficit (both UMNL and LMNL) D - length dependent peripheral neuropathy including AIDP CIDP and other GBS-variants"
X Link 2024-12-01T20:55Z [---] followers, [---] engagements
"EBV - EBV Viral capsid antigen (VCA) - IgG IgM - EBNA (6-12 weeks after onset positive lifelong)"
X Link 2024-12-08T02:16Z [---] followers, [--] engagements
"Drugs that can cause serotonin syndrome: 1) Reduce breakdown - MAOI abx (linezolid) 2) Decrease uptake - SSRI SNRI TCA opioids anti-seizures anti-emetics 3) Increased agonist - lithium 4) Increased release - amphetamines cocaine"
X Link 2024-12-14T21:29Z [---] followers, [--] engagements
"5 mechanism for serotonin syndrome: 1) Decreased breakdown - MAOI abx (linezolid) 2) Decreased reuptake - SSRI SNRI TCA Opioids Antiepileptics Antiemetics 3) Increased agonist - Lithium fentanyl 4) Increased release - stimulants anorectics drugs of abuse 5) CYP2D6 and CYP3A4 inh"
X Link 2024-12-16T07:08Z [---] followers, [--] engagements
"AST and ALT: AST: liver skeletal and cardiac muscle kidney and brain AST mostly in mitochonrial (mAST) 80% and the rest in cytoplasmic (cAST) There's more AST than ALT but half life shorter 18hr vs 36hrs for ALT makes the ratio 1:1"
X Link 2024-12-16T08:36Z [---] followers, [--] engagements
"In cirrhosis: ASTALT - reduced sinusoidal clearance of AST in EtOH B6 reduces production of ALT Also mitochondrial damage causing higher AST release"
X Link 2024-12-16T08:36Z [---] followers, [--] engagements
"Functions & lesions of different brain lobes: #MedX #MedTwitter #Neurology Frontal lobe - motor - personality - primitive reflexes - expressive dysphasia - anosmia - optic nerve compression - gait apraxia"
X Link 2024-12-16T09:29Z [---] followers, [--] engagements
"Parietal lobe - sensory cortex - Gerstmann syndrome - inf quadrantanopia - construction/dressing apraxia - spatial"
X Link 2024-12-16T09:29Z [---] followers, [--] engagements
"Classical pathway for complement - C4 C1 C2 Alternative pathway - C3 Factor H IBD and Properdin. Low C3 and C4 - post-strep SLE Low C3 only - MPGN Low C4 only - SLE"
X Link 2024-12-21T08:30Z [---] followers, [--] engagements
"Increased TLCO: - Pulmonary haemorrhage - Asthma - L to R shunt Reduced TLCO: - ILD - COPD - Lung resection - pHTN - Anaemia - NM Weakness"
X Link 2024-12-21T08:52Z [---] followers, [--] engagements
"CYP inducers: - Quinidine - Barbiturates - St Johns Wart - Phen - Nevirapine - Rifampicin - Griseofulvin - Carbamazepine - Chronic Alcohol - Glucocorticoids"
X Link 2024-12-21T09:04Z [---] followers, [--] engagements
"P-gp - Inducers- St Johns Wart Rifampicin - Substrates - Atorvastatin Tacrolimus Dabigatran Rivaroxaban Losartan Digoxin - Inhibitor - Verapamil Amiodarone Ketoconazole Ritonavir Tacrolimus"
X Link 2024-12-21T09:17Z [---] followers, [--] engagements
"Haemolysis can be divided to extravascular or intravascular:"
X Link 2024-12-27T09:28Z [---] followers, [--] engagements
"Extravascular (outside of vessels) - Intracorpuscular - RBC defects haemoglobinopathies enzyme deficiencies - extracorpuscular - hypersplenism"
X Link 2024-12-27T09:28Z [---] followers, [--] engagements
"JVP: - a wave- atrial contraction - c wave - closure of tricuspid valve - x wave- atrial relaxation - v wave - ventricular contraction - y wave - ventricular emptying"
X Link 2025-01-01T03:59Z [---] followers, [--] engagements
"@MayoClinicINFD Gram negative diplococci of neiserria gonorrhoeae. Can cause reactive arthritis or sometimes Reiter's syndrome (urethritis/epididymitis tenosynovitis/enthesitis/synovitis uveitis) PID (Fitz-Hugh-Curtis Syndrome) - rare"
X Link 2025-01-05T11:48Z [---] followers, [---] engagements
"DPP4i causes physiological GLP1 levels and elevated incretin which acts on alpha cells"
X Link 2025-01-14T09:57Z [---] followers, [--] engagements
"Non-invasive ventilation - only proven for COPD and acute pulmonary edema"
X Link 2025-01-19T06:25Z [---] followers, [--] engagements
"Odds ratio - ratio of exposure in cases to ratio of exposure in control"
X Link 2025-03-17T11:30Z [---] followers, [--] engagements
"Goodpasture's syndrome is associated with anti-alpha3 chain of type IV collagen"
X Link 2025-03-22T23:58Z [---] followers, [--] engagements
"P-gp substrates: Atorvastatin Tacrolimus Dabigatran Rivaroxaban losartan digoxin P-gp inhibitors: Verapamil amiodarone ketoconazole ritonavir tacrolimus. P-gp inducers - Rifampicin St John's Wart"
X Link 2025-04-02T10:12Z [---] followers, [--] engagements
"Pulmonary artery hypertension is related to endothelin A and B causing vasoconstriction"
X Link 2025-04-05T08:26Z [---] followers, [--] engagements
"Classes of antibiotics: 1) Cell wall synthesis inhibitor - Fosfomycin - Beta-lactams (Cephalosporins penicillin carbapenems monobactam) - Glycopeptides (Vancomycin teicoplanin) - Lipopeptides - Daptomycin"
X Link 2025-04-05T23:27Z [---] followers, [--] engagements
"2) DNA synthesis inhibitor - Nitroimidazoles - Metronidazole - Fluoroquinolones - Ciprofloxacin 3) RNA synthesis inhibitor - Rifampicin 4) Ribosome inhibitors - Nitrofurantoin - Oxazolidinones (linezolid) - macrolides - azithro clarithromycin - lincosamides - clindamycin - tetracycline - doxycycline - aminoglycosides - gentamicin 5) metabolite inhibitors - folate antagonist - TMP/SMX"
X Link 2025-04-05T23:27Z [---] followers, [--] engagements
"MecA gene in MRSA leads to PBP2A (less affinity to beta-lactams)"
X Link 2025-04-06T06:27Z [---] followers, [--] engagements
"Incretin cells - from L and K cells - GLP1/GIP works on this - DPP4 destroys incretins"
X Link 2025-04-07T10:49Z [---] followers, [--] engagements
"Types of FTD: - Behavioural - Semantin - Primary progressive aphasia - Non-motor"
X Link 2025-04-08T20:34Z [---] followers, [--] engagements
"Bohr effect - acidity - oxygens binds less well to Hb. Haldane effect - High O2 CO2 binds less well to Hb facilitating release in lungs"
X Link 2025-04-12T09:09Z [---] followers, [--] engagements
"Interferon-gamma release assay detects T-cell responses to ESAT-6 and CFP-10 antigens which are absent in most non-tuberculous mycobacteria but are expressed by a few species such as M. kansasii and M. marinum leading to rare false-positive results"
X Link 2025-04-13T07:56Z [---] followers, [--] engagements
"So what's the difference between SS and NMS - NMS is usually after days to weeks - NMS is caused by DA withdrawal and overdose - NMS has BRADYreflexia and enhanced rigidity without NM excitation Criteria for SS - Hunter and Sternbach"
X Link 2025-05-23T06:50Z [---] followers, [--] engagements
"Treatment: BZD Non-serotonergic antiemetics Severe (Severe hyperthermia and hypoventilation from rigidity) - cyproheptadine and chlorpramazine WH SSRI (Sertraline washout of [--] weeks fluoxetine washout of [--] weeks)"
X Link 2025-05-23T06:50Z [---] followers, [--] engagements
"SLC3A9 gene determines TPMT enzyme function"
X Link 2025-05-24T14:45Z [---] followers, [--] engagements
"KLRG1 on highly differentiated T cells are one of the main pathophysiology for IBM"
X Link 2025-06-21T08:19Z [---] followers, [--] engagements
"Pain is interpretered at the somatosensory cortex via spinothalamic fibres"
X Link 2025-06-21T23:01Z [---] followers, [---] engagements
"JVP waves: - a wave - atrial contraction - c wave - closure of tricuspid valve - x wave - atrial relaxation - v wave - volume filling - y wave - atrial emptying into ventricles"
X Link 2025-06-29T01:33Z [---] followers, [--] engagements
"Alzheimer's finding in FDG-PET - loss of temporo-parietal cortex and posterior cingulate cortex (as opposed to anterior cingulate cortex for FTD)"
X Link 2025-06-29T03:41Z [---] followers, [--] engagements
"Targeting TRVB9 in AxS Exciting https://pubmed.ncbi.nlm.nih.gov/37872223/ https://pubmed.ncbi.nlm.nih.gov/37872223/"
X Link 2025-06-29T07:24Z [---] followers, [--] engagements
"Choice of management for APLS - arterial requires antiplatelet and venous usually anticoagulant but often can be trickier. HCQ in only sAPLS ie in pt with SLE #APLAR25 #APLAR"
X Link 2025-09-07T08:01Z [---] followers, [---] engagements
"Serum IgG4 5x ULN has PPV of 75% for IgG4RD"
X Link 2025-09-11T11:06Z [---] followers, [---] engagements
"Central to problem representation is: 1) Who is the patient 2) What is the tempo 3) Is there a syndrome"
X Link 2025-09-14T10:45Z [---] followers, [--] engagements
"Cocaine is a crystalline alkaloid from cocoa plants with its content of 70% levamisole which is used to cut cocaine - it is a antihelminth agent and previously used for RA and CRC but off the market due to risk of agranulocytosis"
X Link 2025-09-30T07:54Z [---] followers, [--] engagements
"GLP1 comes from L cells and GIP comes from K cells in the SI"
X Link 2025-02-15T11:47Z [---] followers, [--] engagements
"@modernHealthMe Hyperk"
X Link 2025-05-12T21:06Z [---] followers, [----] engagements
"4H and 4Ts of PEA: - Hypoxia - Hypovolemia - Hypothermia - Hypo/hyperK - Thrombosis (Coronary & Pulmonary) - Tamponade - Tension pneumothorax - Toxins"
X Link 2025-05-25T01:59Z [---] followers, [--] engagements
"@simplify_drugs Hyperk as it inhibits RAAS"
X Link 2025-06-21T03:06Z [---] followers, [---] engagements
"4H and Ts of PEA: - hypoxia hypovolemia hypothermia and hypo/hyperK - thrombus tension pneumothorax toxin and tamponade"
X Link 2025-07-22T12:09Z [---] followers, [--] engagements
"HLADRB1*11:01 is associated with statin induced myositis"
X Link 2025-09-13T23:30Z [---] followers, [---] engagements
"RTX and TCZ are the best options for patients with ILD with CTD"
X Link 2025-10-12T12:03Z [---] followers, [---] engagements
"Causes of cardiac mass: 1) Thrombus 2) Vegetations (endocarditis) 3) Benign masses - atrial myxoma papillary fibroelastoma lipoma rhabdomyoma 4) Malignant masses - angiosarcoma rhabdomyosarcoma metastases (lung breast kidney melanoma) 5) Cardiac lymphoma Definity TTE PET transcutaneous catheter with biopsy could be useful. https://twitter.com/i/web/status/1989852785236676892 https://twitter.com/i/web/status/1989852785236676892"
X Link 2025-11-16T00:27Z [---] followers, [--] engagements
"Classes of antihistamines: 1st gen - chlorphenamine promethazine and diphenhydramine 2nd gen - loratidine ceterizine and fexofenadine"
X Link 2025-11-16T01:50Z [---] followers, [--] engagements
"HSV encephalitis tends to affect medial temporal orbitofrontal and insular cortex"
X Link 2025-11-21T21:22Z [---] followers, [--] engagements
"Babinski-negotte syndrome is associated with mixed medial and lateral medullary syndromes ie involvement of sympathetic pathway + Wallenberg syndrome"
X Link 2025-12-24T22:08Z [---] followers, [--] engagements
"@MTD_MED @IhabFathiSulima Lamotrigine is the most common cause of SJS/TENS among AEDs although genotype HLAB1502 carries the risk for CMZ"
X Link 2025-12-26T01:54Z [---] followers, [----] engagements
"@hemo_shk @IhabFathiSulima En coup de sabre a form of Morphea"
X Link 2026-01-02T10:31Z [---] followers, [---] engagements
"@DrMedica_13 Fe def with angular stomatitis"
X Link 2026-01-16T22:08Z [---] followers, [--] engagements
"Gout can present with occular manifestations ie scleritis scleral tophii and other red eye symptoms"
X Link 2026-01-17T09:58Z [---] followers, [--] engagements
"@knowmedge Colchicine Followed by AZA IL-1 and IVIg"
X Link 2026-01-24T00:54Z [---] followers, [---] engagements
"@DrAkhilX @BJSurgery Thomas sign of malignancy at ampulla of vater"
X Link 2026-02-13T21:48Z [---] followers, [----] engagements
"Pizotifen (used in migraine prophylaxis) can cause weight gain"
X Link 2023-01-07T08:49Z [---] followers, [---] engagements
"Low albumin can cause a falsely low anion gap"
X Link 2026-01-28T10:03Z [---] followers, [---] engagements
"Class III and IV lupus nephritis are the window to aggressive treatment albeit with MMF vs AZA CNI Belimumab +/- Ritux HCQ and RAASi"
X Link 2026-01-29T11:45Z [---] followers, [---] engagements
"Although in RAVE trial the use of rituximab in induction of AAV did not include patients with severe renal impairment the RITUXVAS trial has proven that it is in fact non-inferior to CYC or AZA in induction. Furthermore MAINRITSAN trials prove RTX to be a fantastic drug for maintenance in AAV (mainly GPA and MPA) #Rheumatology #MedX https://twitter.com/i/web/status/2017498823686557994 https://twitter.com/i/web/status/2017498823686557994"
X Link 2026-01-31T07:22Z [---] followers, [---] engagements
"Migratory oligoarthritis: Gonococcal Rheumatic fever SLE AAV (especially GPA)"
X Link 2026-02-01T19:39Z [---] followers, [---] engagements
"HIV testing can be falsely negative within the [--] days of acquisition"
X Link 2026-02-05T19:44Z [---] followers, [---] engagements
"B) LBD characterized by fluctuation in hallucinations mimicking delirium with lilliputian hallucinations. Often presents with motor symptoms approximately a year after. Minimal response to dopamine replacement/agonists trial of anti-acetylcholinesterase inhibitors recommended https://twitter.com/i/web/status/2020248677361795482 https://twitter.com/i/web/status/2020248677361795482"
X Link 2026-02-07T21:29Z [---] followers, [---] engagements
"Tests for rotator cuff: - Hawkin's test (impingement) - Full can and empty can - supraspinatous - External rotation - infraspinatous - Lift off test or belly test - subscapularis - Hornblower test - teres minor"
X Link 2026-02-08T05:15Z [---] followers, [----] engagements
"Tests for SIJ: - FABER test - Yeaman's test - Gaelan's test"
X Link 2026-02-08T05:16Z [---] followers, [----] engagements
"Anti-Jo1 ASyS is associated with HLADRB103:01 whereas HMGCr Myositis is associated with HLADRB111:01"
X Link 2026-02-08T05:29Z [---] followers, [----] engagements
"Polymyositis is now exceedingly rare with the absence if extramuscular manifestation and current data demonstrates it can be likely divided into IMNM ASyS and overlap myositis"
X Link 2026-02-08T05:31Z [---] followers, [---] engagements
"IBM is unique in which it affects knee extensors and finger flexors"
X Link 2026-02-08T05:32Z [---] followers, [---] engagements
"Secondary causes of Raynauds: - CTD - medications (beta-blockers amphetamine migraine meds IFN chemotherapy) - paraneoplastic - haematological ie cryoglobulin cold agglutinin"
X Link 2026-02-09T19:50Z [---] followers, [----] engagements
"For treatment of Raynauds: - PDE5 is sildenafil - prostacyclin analogue ie Illoprost treprostenil - DHPCCB ie nifedipine For prevention of Raynauds; - endothelin antagonist ie bosentan - prostacyclin analogue ie Illoprost treprostenil - DHPCCB ie nifedipine"
X Link 2026-02-09T19:52Z [---] followers, [----] engagements
"Using a 512Hz tuning fork: Rinne's test - Placed over mastoid process usually ACBC but if BCAC - Conductive hearing loss Confirming that with Weber test: - sound localizes to bad sidee in conductive HL and to the good side in SNHL"
X Link 2026-02-10T10:01Z [---] followers, [---] engagements
"Flecainide and Ajmalline challenge test could be used to diagnose Brugada syndrome"
X Link 2026-02-10T19:23Z [---] followers, [---] engagements
"Use of beta-blockers in phaeochromocytoma may lead to unopposed alpha-adrenergic stimulation"
X Link 2026-02-11T22:17Z [---] followers, [----] engagements
"Approach to N&V: 1) Ask if it's related to a syndrome ie Headache SOB 2) Episodic ie triggered by food Consider sphincter obstruction 3) Continuous Severe - CNS Cardiac GI pathology - non-severe - consider metabolic causes ie drugs toxins electrolyte disturbances"
X Link 2026-02-13T21:50Z [---] followers, [----] engagements
"Cancer risk in inflammatory myopathies: 1) High risk - TIF1gamma and NXP2 dysphagia cutaneous persistently high disease activity age40 onset 2) Medium risk - SAE HMGCR MI2 MDA5 male sex 3) Low risk - Jo-1 SRP cN1a(IBM) ILD arthropathy Raynaud's #Rheumatology #MedX"
X Link 2026-02-14T21:38Z [---] followers, [----] engagements
"In glomerulonephritis: - Low C3 and C4 - Lupus nephritis - Low C4 - cryoglobulinaemia - Low C3 - MPGN and post-infectious GN"
X Link 2026-02-08T05:35Z [---] followers, 39.5K engagements
"t814 - Burkitt lymphoma t1114 - Mantle cell lymphoma t14:18 - Follicular lymphoma"
X Link 2026-02-11T21:21Z [---] followers, [----] engagements
"Opthalmic manifestations of GCA - AION - PION - CRAO - BRAO - Choroidal ischaemia"
X Link 2026-02-14T22:27Z [---] followers, [----] engagements
"Among all inflammatory myopathies ASyS overlap myositis and IBM are most associated with gastrointestinal symptoms. Articular ASyS and overlap myositis. Cardiac ASyS and IMNM"
X Link 2026-02-15T01:06Z [---] followers, [---] engagements
"What a wonderful experience at #ARANZRA24 . It was filled with so much learning and fantastic interactions Also a huge thank you to [--] very inspirational mentors of mine Dr Andrew Foote and Dr Mueed Mian for guiding me through my research projects. @AusRheum"
X Link 2024-05-21T07:14Z [---] followers, [----] engagements
"OSA can cause right heart failure through cor pulmonale- however with time it can cause left heart failure too secondary to chronically high intrathoracic pressure sympathetic drive and afterload"
X Link 2026-02-15T19:54Z [---] followers, [---] engagements
"Darier sign where mild trauma can induce erythema and itch can be found in urticaria pigmentosa or systemic mastocytosis"
X Link 2026-02-15T19:53Z [---] followers, [---] engagements
"Testicular germ-cell tumour: - Seminomas - normal AFP sometimes high bHCG and LDH - Non-seminomas - high AFP and more commonly high bHCG and LDH"
X Link 2026-02-15T07:47Z [---] followers, [----] engagements
"Ovoid palatal patch can be seen in TIF1gamma DM. https://scispace.com/pdf/ovoid-palatal-patch-in-dermatomyositis-a-novel-finding-5aqpn1nfwz.pdf https://scispace.com/pdf/ovoid-palatal-patch-in-dermatomyositis-a-novel-finding-5aqpn1nfwz.pdf"
X Link 2026-02-15T07:46Z [---] followers, [---] engagements
"Among all inflammatory myopathies ASyS overlap myositis and IBM are most associated with gastrointestinal symptoms. Articular ASyS and overlap myositis. Cardiac ASyS and IMNM"
X Link 2026-02-15T01:06Z [---] followers, [---] engagements
"Differentials for PMR: - seronegative RA - regional soft tissue rheumatism - subacromial bursitis or supraspinatous tendonitis - myeloma - myositis - drug-induced myopathy - parkinson's (coat-hanger) - central sensitization"
X Link 2026-02-14T22:32Z [---] followers, [---] engagements
"Opthalmic manifestations of GCA - AION - PION - CRAO - BRAO - Choroidal ischaemia"
X Link 2026-02-14T22:27Z [---] followers, [----] engagements
"4 subtypes of GCA - GCA with cranial symptoms - Symptoms of LVV ie limb claudication - Fever subtype - PMR with vasculitis on imaging"
X Link 2026-02-14T22:26Z [---] followers, [---] engagements
"Giant cell arteritis (GCA) can involve any arteries including external carotid branches (temporal and occipital) opthalmic vertebral distal subclavian and axillary arteries thoracic aorta"
X Link 2026-02-14T21:47Z [---] followers, [----] engagements
"Interstitial lung disease patterns: NSIP - bilateral GGO with fine reticulation and traction bronchiectasis lower lobe predominant and subpleural sparing UIP - honey combing traction bronchiectasis basal subpleural reticulation LIP - GGO with thin-walled cysts and interlobular septal thickening OP - Patchy consolidation reverse halo sign AIP - Rapidly progressive diffuse alveolar opacities #Rheumatology #Pulmonology #MedX"
X Link 2026-02-14T21:42Z [---] followers, [----] engagements
"Cancer risk in inflammatory myopathies: 1) High risk - TIF1gamma and NXP2 dysphagia cutaneous persistently high disease activity age40 onset 2) Medium risk - SAE HMGCR MI2 MDA5 male sex 3) Low risk - Jo-1 SRP cN1a(IBM) ILD arthropathy Raynaud's #Rheumatology #MedX"
X Link 2026-02-14T21:38Z [---] followers, [----] engagements
"Screening panel: - CT- neck thorax abdomen and pelvis - cervical screening - mammography - PSA - CA125 - pelvic/transvaginal ultrasonography - FOBT - nasoendoscopy - FDG-PET"
X Link 2026-02-14T21:38Z [---] followers, [---] engagements
"Loading medications are sometimes used in medications with long half life"
X Link 2026-02-14T09:53Z [---] followers, [---] engagements
"Ketamine can cause bladder dysfunction"
X Link 2026-02-14T09:52Z [---] followers, [---] engagements
"Duchenne muscular dystrophy can sometimes lead to dilated cardiomyopathy"
X Link 2026-02-14T09:23Z [---] followers, [---] engagements
"Topiramate causes renal calculi via alkalisation of urine and hypocitraturia"
X Link 2026-02-14T09:22Z [---] followers, [---] engagements
"Avacopan can be used as induction for ANCA vasculitis"
X Link 2026-02-14T06:29Z [---] followers, [---] engagements
"Pauci-immune RPGN is characteristic of ANCA vasculitis"
X Link 2026-02-14T06:21Z [---] followers, [---] engagements
"10% of patients with ANCA vasculitis are seronegative"
X Link 2026-02-14T06:18Z [---] followers, [---] engagements
"Classes of lupus nephritis: Class [--] - minimal mental Class [--] - mesangioproliferative Class [--] - focal proliferative Class [--] - diffuse proliferative Class [--] - membranous Class [--] - advanced sclerosing #nephrology #medX"
X Link 2026-02-14T00:52Z [---] followers, [----] engagements
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