[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @andrewcaravello Andrew Caravello, DO Andrew Caravello, DO posts on X about $nwbo, $mrk, $amgn, infrastructure the most. They currently have XXXXX followers and XXX posts still getting attention that total XXX engagements in the last XX hours. ### Engagements: XXX [#](/creator/twitter::244291506/interactions)  - X Week XXXXXX +99% - X Month XXXXXX -XX% - X Months XXXXXXXXX +9,519% - X Year XXXXXXXXX +2,754% ### Mentions: XX [#](/creator/twitter::244291506/posts_active)  - X Week XX -X% - X Month XX -XX% - X Months XXX +2,671% - X Year XXX +1,043% ### Followers: XXXXX [#](/creator/twitter::244291506/followers)  - X Week XXXXX +1% - X Month XXXXX +2% - X Months XXXXX +153% - X Year XXXXX +141% ### CreatorRank: XXXXXXXXX [#](/creator/twitter::244291506/influencer_rank)  ### Social Influence [#](/creator/twitter::244291506/influence) --- **Social category influence** [stocks](/list/stocks) XXXX% [countries](/list/countries) XXXX% [cryptocurrencies](/list/cryptocurrencies) XXXX% [technology brands](/list/technology-brands) XXXX% **Social topic influence** [$nwbo](/topic/$nwbo) #3, [$mrk](/topic/$mrk) #37, [$amgn](/topic/$amgn) #11, [infrastructure](/topic/infrastructure) #2101, [$zeoaf](/topic/$zeoaf) 0.39%, [ohio](/topic/ohio) 0.39%, [snaps](/topic/snaps) 0.39%, [withdrawal](/topic/withdrawal) 0.39%, [$nvo](/topic/$nvo) 0.39%, [novartis](/topic/novartis) XXXX% **Top accounts mentioned or mentioned by** [@alphavestcap](/creator/undefined) [@dcvaxdefender](/creator/undefined) [@d_stock07734](/creator/undefined) [@maveric92283613](/creator/undefined) [@peterdfellow](/creator/undefined) [@flemmingbruce](/creator/undefined) [@dstock07734](/creator/undefined) [@andrewecker829](/creator/undefined) [@tonyverazzanno](/creator/undefined) [@dcvaxcohenm](/creator/undefined) [@dogesec](/creator/undefined) [@cohenmilstein](/creator/undefined) [@jaygreco194737](/creator/undefined) [@advancegradert](/creator/undefined) [@aponiaanalytics](/creator/undefined) [@kauricapital](/creator/undefined) [@jascanlan](/creator/undefined) [@theroaringkitty](/creator/undefined) [@wallstreetbets](/creator/undefined) [@mhragovuk](/creator/undefined) **Top assets mentioned** [Merck & Co., Inc. (MRK)](/topic/$mrk) [Amgen, Inc. (AMGN)](/topic/$amgn) [Novo-Nordisk (NVO)](/topic/$nvo) [Novartis AG (NVS)](/topic/novartis) [Bluefin (BLUE)](/topic/$blue) [Gilead Sciences, Inc. (GILD)](/topic/$gild) [Vertex Protocol (VRTX)](/topic/$vrtx) [Regeneron Pharmaceuticals Inc (REGN)](/topic/$regn) ### Top Social Posts [#](/creator/twitter::244291506/posts) --- Top posts by engagements in the last XX hours "🧬 The Immune OS Theory How $NWBO #DCVax Network May Quietly Align $MRK $AMGN $ZEOAF Advent and #RevImmune into a Global Architecture Poised to Launch. Absolutely @mazzulo_lorie this is where the whole map finally snaps into focus. Everything weve been piecing together #AdventBioServices in the UK Mercks Winterfell fortress in Pennsylvania Amgens digital citadel in Ohio Zeons polymer-and-microfluidic ecosystem the Eden automation engine and RevImmunes IL-7 renewal layer now forms a single logical picture. It remains a theory built entirely from public data and reasoned inference but the" [X Link](https://x.com/andrewcaravello/status/1978663140733702548) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-16T03:23Z 1262 followers, 3300 engagements "🧬 The Duffy Vector How a Nine-Month Detour Quietly Aligned $MRK with $NWBO and Why Winterfell Exists #DCVax #Keytruda #Yervoy #Merck #NWBO #BMS #Winterfell #PolyICLC #IL2 #IL7 🕯 Prologue A Line on a Rsum In September 2019 a small Maryland company called Northwest Biotherapeutics announced that Kevin T. Duffy Ph.D. M.B.A.a senior scientist from Merck & Co. who had spent five years orchestrating Keytrudas scientific-affairs networkwas joining as Vice President of Medical Affairs and External Collaborations. To most it was a footnote. To those who trace corporate choreography through quiet" [X Link](https://x.com/andrewcaravello/status/1978578954098528476) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-15T21:49Z 1262 followers, 3892 engagements "🧩 The Great Retreat: How $NWBO #DCVax and #AdventBioServices Built the Immune Infrastructure Big Pharma Walked Away From TLDR Between 2023 and 2025 nearly every major pharmaceutical company that once promised a revolution in cell therapy has stepped back. $NVO (Novo Nordisk) $TAK (Takeda) $GILD (Gilead) $RHHBY (Roche / Genentech) $VRTX (Vertex) $NVS (Novartis) and $BLUE (Bluebird Bio) have all scaled down or abandoned programs once hailed as the future of medicine. The official languagestrategic focus portfolio optimization efficiency realignmentmasks a deeper truth: the biology works the" [X Link](https://x.com/andrewcaravello/status/1978954812940026168) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-16T22:42Z 1262 followers, 2546 engagements "🧬 The Signal Beneath the Silence: How Manufacturing Became the Brain of the Immune OS with $NWBO #AdventBioServices $MRK $REGN $AMGN and the #PromisingPathwayAct Preface This essay expands on a single question: why would Northwest Biotherapeutics need a U.S. manufacturing site before approval The answer reveals how manufacturing regulation and biology have merged into one living system. TLDR Mercks abrupt retreat from the United Kingdom the United States one-hundred-percent tariff on imported branded drugs and Northwest Biotherapeutics preparing a U.S. site are not isolated events. They are" [X Link](https://x.com/andrewcaravello/status/1979150989958562094) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-17T11:42Z 1262 followers, 1664 engagements "🧬 LTI92355 $RNTX: Cav1 Trapdoor Booster to Prime $NWBO #DCVax A Yorkville Signal TLDR Caveolin1 (Cav1) is a small structural protein that builds trapdoors in cell membranes. These trapdoors decide three critical things: whether dendritic cells can reach lymph nodes to teach whether Tcells can cross barriers like the bloodbrain barrier and whether tumor antigens are visible as targets. In 2025 Rein Therapeutics showed in human tissue that its Cav1 peptide drug LTI92355 could restore this function making diseased immune cells better at phagocytosis and less suppressive. Northwest" [X Link](https://x.com/andrewcaravello/status/1968027863728459962) [@andrewcaravello](/creator/x/andrewcaravello) 2025-09-16T19:03Z 1259 followers, 1988 engagements "Thats a great point and I appreciate you bringing it up. Youre right that Kevin Duffy appears to be at Regeneron now and that actually aligns with the way his career has evolved. Its reasonable to think that his work at NWBO was project-based. His background has always been in building bridges between science infrastructure and regulatory readiness. At Merck he helped coordinate external collaborations around the Keytruda program and when he joined NWBO his focus seemed to be evaluating and aligning the companys scientific and operational framework ahead of regulatory engagement. People with" [X Link](https://x.com/andrewcaravello/status/1978857330725818623) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-16T16:15Z 1260 followers, XXX engagements "🧬 The Leadership Equation and the #AWS Model Behind $NWBO Next Chapter Its natural to ask what happens when a company like Northwest Biotherapeutics led for two decades by its founding team finally crosses from regulatory limbo to commercial reality. Linda Powers turns XX next year. Les Goldman Dr. Marnix Bosch and the rest of the early guard are all veterans of the field. So the question feels obvious: can they keep running the company after MHRA approval The short answer is yes not only can they stay but there are powerful reasons why they should. 🧠The Continuity Argument: Experience Is" [X Link](https://x.com/andrewcaravello/status/1978773666134360490) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-16T10:43Z 1262 followers, XXX engagements "The Disappearing Combo How a withdrawn trial at #UCLA revealed the quiet architecture connecting $BMS $MRK and $NWBO and the people who taught the immune system to remember Prologue The Vanished Trial The notice appeared without ceremony. A single line on described a new study at UCLAs Jonsson Comprehensive Cancer Center. Patients with lethal brain tumors would receive two of Bristol Myers Squibbs most famous checkpoint inhibitorsYervoy (ipilimumab) and Opdivo (nivolumab)alongside a dendritic-cell vaccine made from their own tumors. It was small careful and quietly revolutionary: acceleration" [X Link](https://x.com/andrewcaravello/status/1977918273191661711) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-14T02:03Z 1262 followers, 4063 engagements "$NWBO #DCVax #GBM Why the Trial Disappeared A Working Theory What follows isnt confirmed fact but reasoned speculation based on public information clinical timelines and whats known about the patents and people involved. No one outside those meetings knows exactly what happened but when you line up the evidence a picture begins to form. X. The Visible Part: A Trial That Blinked Out In 2023 UCLA registered a small ambitious study. Patients with brain tumors would receive Bristol Myers Squibbs two major checkpoint inhibitors Yervoy (ipilimumab) and Opdivo (nivolumab) alongside a dendritic-cell" [X Link](https://x.com/andrewcaravello/status/1978056008036433973) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-14T11:11Z 1262 followers, 2545 engagements "CAR-T cells are indeed living but they are genetically engineered artificial in design and short-lived in function. They begin as a patients own T cells but in the lab they are reprogrammed with a synthetic gene that encodes a Chimeric Antigen Receptor (CAR) an artificial structure made by fusing antibody and T-cell signaling domains that do not naturally exist together in the body. This modification forces the cell to attack one specific antigen bypassing the immune systems normal checks and balances. Because they are hyper-activated and engineered CAR-T therapies often cause significant" [X Link](https://x.com/andrewcaravello/status/1979181642477437184) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-17T13:44Z 1262 followers, XX engagements "🧬 Re-Educating the Immune System: How a $NWBO #DCVax Platform Could End Vasculitis Forever (Based on Nature Scientific Reports 2025: 🧠I. The Disease That Steals Sight Giant Cell Arteritis (GCA) sometimes called temporal arteritis is the most common primary systemic vasculitis in adults over XX. Its not a trivial headache disorderits an immunologic emergency capable of blinding a patient within hours. The inflammation targets the medium and large arteries especially the temporal branches of the carotid the ophthalmic and sometimes the aorta itself. Symptoms unfold like a warning in slow" [X Link](https://x.com/andrewcaravello/status/1979268393988505636) [@andrewcaravello](/creator/x/andrewcaravello) 2025-10-17T19:28Z 1262 followers, XXX engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@andrewcaravello Andrew Caravello, DO
Andrew Caravello, DO posts on X about $nwbo, $mrk, $amgn, infrastructure the most. They currently have XXXXX followers and XXX posts still getting attention that total XXX engagements in the last XX hours.
Engagements: XXX #
- X Week XXXXXX +99%
- X Month XXXXXX -XX%
- X Months XXXXXXXXX +9,519%
- X Year XXXXXXXXX +2,754%
Mentions: XX #
- X Week XX -X%
- X Month XX -XX%
- X Months XXX +2,671%
- X Year XXX +1,043%
Followers: XXXXX #
- X Week XXXXX +1%
- X Month XXXXX +2%
- X Months XXXXX +153%
- X Year XXXXX +141%
CreatorRank: XXXXXXXXX #
Social Influence #
Social category influence stocks XXXX% countries XXXX% cryptocurrencies XXXX% technology brands XXXX%
Social topic influence $nwbo #3, $mrk #37, $amgn #11, infrastructure #2101, $zeoaf 0.39%, ohio 0.39%, snaps 0.39%, withdrawal 0.39%, $nvo 0.39%, novartis XXXX%
Top accounts mentioned or mentioned by @alphavestcap @dcvaxdefender @d_stock07734 @maveric92283613 @peterdfellow @flemmingbruce @dstock07734 @andrewecker829 @tonyverazzanno @dcvaxcohenm @dogesec @cohenmilstein @jaygreco194737 @advancegradert @aponiaanalytics @kauricapital @jascanlan @theroaringkitty @wallstreetbets @mhragovuk
Top assets mentioned Merck & Co., Inc. (MRK) Amgen, Inc. (AMGN) Novo-Nordisk (NVO) Novartis AG (NVS) Bluefin (BLUE) Gilead Sciences, Inc. (GILD) Vertex Protocol (VRTX) Regeneron Pharmaceuticals Inc (REGN)
Top Social Posts #
Top posts by engagements in the last XX hours
"🧬 The Immune OS Theory How $NWBO #DCVax Network May Quietly Align $MRK $AMGN $ZEOAF Advent and #RevImmune into a Global Architecture Poised to Launch. Absolutely @mazzulo_lorie this is where the whole map finally snaps into focus. Everything weve been piecing together #AdventBioServices in the UK Mercks Winterfell fortress in Pennsylvania Amgens digital citadel in Ohio Zeons polymer-and-microfluidic ecosystem the Eden automation engine and RevImmunes IL-7 renewal layer now forms a single logical picture. It remains a theory built entirely from public data and reasoned inference but the"
X Link @andrewcaravello 2025-10-16T03:23Z 1262 followers, 3300 engagements
"🧬 The Duffy Vector How a Nine-Month Detour Quietly Aligned $MRK with $NWBO and Why Winterfell Exists #DCVax #Keytruda #Yervoy #Merck #NWBO #BMS #Winterfell #PolyICLC #IL2 #IL7 🕯 Prologue A Line on a Rsum In September 2019 a small Maryland company called Northwest Biotherapeutics announced that Kevin T. Duffy Ph.D. M.B.A.a senior scientist from Merck & Co. who had spent five years orchestrating Keytrudas scientific-affairs networkwas joining as Vice President of Medical Affairs and External Collaborations. To most it was a footnote. To those who trace corporate choreography through quiet"
X Link @andrewcaravello 2025-10-15T21:49Z 1262 followers, 3892 engagements
"🧩 The Great Retreat: How $NWBO #DCVax and #AdventBioServices Built the Immune Infrastructure Big Pharma Walked Away From TLDR Between 2023 and 2025 nearly every major pharmaceutical company that once promised a revolution in cell therapy has stepped back. $NVO (Novo Nordisk) $TAK (Takeda) $GILD (Gilead) $RHHBY (Roche / Genentech) $VRTX (Vertex) $NVS (Novartis) and $BLUE (Bluebird Bio) have all scaled down or abandoned programs once hailed as the future of medicine. The official languagestrategic focus portfolio optimization efficiency realignmentmasks a deeper truth: the biology works the"
X Link @andrewcaravello 2025-10-16T22:42Z 1262 followers, 2546 engagements
"🧬 The Signal Beneath the Silence: How Manufacturing Became the Brain of the Immune OS with $NWBO #AdventBioServices $MRK $REGN $AMGN and the #PromisingPathwayAct Preface This essay expands on a single question: why would Northwest Biotherapeutics need a U.S. manufacturing site before approval The answer reveals how manufacturing regulation and biology have merged into one living system. TLDR Mercks abrupt retreat from the United Kingdom the United States one-hundred-percent tariff on imported branded drugs and Northwest Biotherapeutics preparing a U.S. site are not isolated events. They are"
X Link @andrewcaravello 2025-10-17T11:42Z 1262 followers, 1664 engagements
"🧬 LTI92355 $RNTX: Cav1 Trapdoor Booster to Prime $NWBO #DCVax A Yorkville Signal TLDR Caveolin1 (Cav1) is a small structural protein that builds trapdoors in cell membranes. These trapdoors decide three critical things: whether dendritic cells can reach lymph nodes to teach whether Tcells can cross barriers like the bloodbrain barrier and whether tumor antigens are visible as targets. In 2025 Rein Therapeutics showed in human tissue that its Cav1 peptide drug LTI92355 could restore this function making diseased immune cells better at phagocytosis and less suppressive. Northwest"
X Link @andrewcaravello 2025-09-16T19:03Z 1259 followers, 1988 engagements
"Thats a great point and I appreciate you bringing it up. Youre right that Kevin Duffy appears to be at Regeneron now and that actually aligns with the way his career has evolved. Its reasonable to think that his work at NWBO was project-based. His background has always been in building bridges between science infrastructure and regulatory readiness. At Merck he helped coordinate external collaborations around the Keytruda program and when he joined NWBO his focus seemed to be evaluating and aligning the companys scientific and operational framework ahead of regulatory engagement. People with"
X Link @andrewcaravello 2025-10-16T16:15Z 1260 followers, XXX engagements
"🧬 The Leadership Equation and the #AWS Model Behind $NWBO Next Chapter Its natural to ask what happens when a company like Northwest Biotherapeutics led for two decades by its founding team finally crosses from regulatory limbo to commercial reality. Linda Powers turns XX next year. Les Goldman Dr. Marnix Bosch and the rest of the early guard are all veterans of the field. So the question feels obvious: can they keep running the company after MHRA approval The short answer is yes not only can they stay but there are powerful reasons why they should. 🧠The Continuity Argument: Experience Is"
X Link @andrewcaravello 2025-10-16T10:43Z 1262 followers, XXX engagements
"The Disappearing Combo How a withdrawn trial at #UCLA revealed the quiet architecture connecting $BMS $MRK and $NWBO and the people who taught the immune system to remember Prologue The Vanished Trial The notice appeared without ceremony. A single line on described a new study at UCLAs Jonsson Comprehensive Cancer Center. Patients with lethal brain tumors would receive two of Bristol Myers Squibbs most famous checkpoint inhibitorsYervoy (ipilimumab) and Opdivo (nivolumab)alongside a dendritic-cell vaccine made from their own tumors. It was small careful and quietly revolutionary: acceleration"
X Link @andrewcaravello 2025-10-14T02:03Z 1262 followers, 4063 engagements
"$NWBO #DCVax #GBM Why the Trial Disappeared A Working Theory What follows isnt confirmed fact but reasoned speculation based on public information clinical timelines and whats known about the patents and people involved. No one outside those meetings knows exactly what happened but when you line up the evidence a picture begins to form. X. The Visible Part: A Trial That Blinked Out In 2023 UCLA registered a small ambitious study. Patients with brain tumors would receive Bristol Myers Squibbs two major checkpoint inhibitors Yervoy (ipilimumab) and Opdivo (nivolumab) alongside a dendritic-cell"
X Link @andrewcaravello 2025-10-14T11:11Z 1262 followers, 2545 engagements
"CAR-T cells are indeed living but they are genetically engineered artificial in design and short-lived in function. They begin as a patients own T cells but in the lab they are reprogrammed with a synthetic gene that encodes a Chimeric Antigen Receptor (CAR) an artificial structure made by fusing antibody and T-cell signaling domains that do not naturally exist together in the body. This modification forces the cell to attack one specific antigen bypassing the immune systems normal checks and balances. Because they are hyper-activated and engineered CAR-T therapies often cause significant"
X Link @andrewcaravello 2025-10-17T13:44Z 1262 followers, XX engagements
"🧬 Re-Educating the Immune System: How a $NWBO #DCVax Platform Could End Vasculitis Forever (Based on Nature Scientific Reports 2025: 🧠I. The Disease That Steals Sight Giant Cell Arteritis (GCA) sometimes called temporal arteritis is the most common primary systemic vasculitis in adults over XX. Its not a trivial headache disorderits an immunologic emergency capable of blinding a patient within hours. The inflammation targets the medium and large arteries especially the temporal branches of the carotid the ophthalmic and sometimes the aorta itself. Symptoms unfold like a warning in slow"
X Link @andrewcaravello 2025-10-17T19:28Z 1262 followers, XXX engagements