[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @andrewcaravello Andrew Caravello, DO Andrew Caravello, DO posts on X about $nwbo, $mrk, $azn, convergence the most. They currently have XXXXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours. ### Engagements: XXXXX [#](/creator/twitter::244291506/interactions)  - X Week XXXXXX -XX% - X Month XXXXXXX -XX% - X Months XXXXXXXXX +8,298% - X Year XXXXXXXXX +2,263% ### Mentions: XX [#](/creator/twitter::244291506/posts_active)  - X Month XX -XX% - X Months XX +1,417% - X Year XX +246% ### Followers: XXXXX [#](/creator/twitter::244291506/followers)  - X Week XXXXX +2.60% - X Month XXXXX +20% - X Months XXXXX +130% - X Year XXXXX +153% ### CreatorRank: XXXXXXX [#](/creator/twitter::244291506/influencer_rank)  ### Social Influence [#](/creator/twitter::244291506/influence) --- **Social category influence** [stocks](/list/stocks) XXXXX% [currencies](/list/currencies) XXXX% [finance](/list/finance) XXXX% [cryptocurrencies](/list/cryptocurrencies) XXX% **Social topic influence** [$nwbo](/topic/$nwbo) #1, [$mrk](/topic/$mrk) 10.81%, [$azn](/topic/$azn) 8.11%, [convergence](/topic/convergence) 8.11%, [signals](/topic/signals) 5.41%, [dawn](/topic/dawn) 5.41%, [listing](/topic/listing) 2.7%, [$bgne](/topic/$bgne) 2.7%, [$nbix](/topic/$nbix) 2.7%, [$vrtx](/topic/$vrtx) XXX% **Top accounts mentioned or mentioned by** [@maveric92283613](/creator/undefined) [@alphavestcap](/creator/undefined) [@d_stock07734](/creator/undefined) [@dogesec](/creator/undefined) [@secgov](/creator/undefined) [@cohenmilstein](/creator/undefined) [@drscottarthurmps](/creator/undefined) [@dstock07734](/creator/undefined) [@metacollectiveg](/creator/undefined) [@mittypost](/creator/undefined) [@dcvaxcohenm](/creator/undefined) [@gr197667](/creator/undefined) [@dcvaxdefender](/creator/undefined) [@philburginvests](/creator/undefined) [@cheesehammer11](/creator/undefined) [@pjc3251](/creator/undefined) [@le6156783881615](/creator/undefined) [@ajw02360](/creator/undefined) [@joekent41483789](/creator/undefined) [@kennethpar49290](/creator/undefined) **Top assets mentioned** [Merck & Co., Inc. (MRK)](/topic/$mrk) [AstraZeneca PLC (AZN)](/topic/$azn) [Neurocrine Biosciences, Inc. (NBIX)](/topic/$nbix) [Vertex Protocol (VRTX)](/topic/$vrtx) [Biogen Inc (BIIB)](/topic/$biib) [Gilead Sciences, Inc. (GILD)](/topic/$gild) [Regeneron Pharmaceuticals Inc (REGN)](/topic/$regn) [Eli Lilly and Company (LLY)](/topic/$lly) [Novartis AG (NVS)](/topic/$nvs) [Johnson & Johnson (JNJ)](/topic/$jnj) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [Pfizer, Inc. (PFE)](/topic/$pfe) [Amgen, Inc. (AMGN)](/topic/$amgn) [Seagen Inc (SGEN)](/topic/$sgen) [Incyte Corporation (INCY)](/topic/$incy) [Madrigal Pharmaceuticals, Inc. Common Stock (MDGL)](/topic/$mdgl) [Exelixis Inc (EXEL)](/topic/$exel) [Acadia Pharmaceuticals Inc. (ACAD)](/topic/$acad) ### Top Social Posts [#](/creator/twitter::244291506/posts) --- Top posts by engagements in the last XX hours "$NWBO 🛸 The Signal That Was Jammed by $MRK (Part Deux) How Three Dendritic Cell Trials in Colorectal Cancer Were Silenced (Until They Werent) 🗞 Why I Deleted the Original Post On July X I deleted the first version of this post originally titled The Signal That Was Jammed. It was based on a promising but misdirected listing (NCT03735290) that pointed to a different terminated study a basket trial using an allogeneic dendritic cell vaccine with checkpoint inhibitors in cold tumors like gastric and gastroesophageal junctional adenocarcinomas. It wasnt the Roswell colorectal trial I was looking"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1943273438153433431) 2025-07-10 11:37:46 UTC 1063 followers, 3059 engagements "continued $NWBO $MRK $BMY $AZN $JNJ $PFE $NVS $LLY $REGN $AMGN $GILD $RHHBY $ROG.VX $BIIB $SGEN $VRTX $NBIX $INCY $BGNE $MDGL $EXEL $ACAD 🧬 X. Replacing Chemoand Eventually Surgery DCVax is immunologically constructive. Chemo is destructive. And with DCVax-Direct intratumoral injections can: Cause in situ vaccination Shrink tumors Release danger signals that retrain the immune system Stacked with IL-7 cytokines or checkpoint inhibitors this platform could eliminate the need for debulking surgery in some settings. 🔄 The Self-Feeding Immune Loop DCVax sets in motion a loop: 1.Priming Trains"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1930815053906715102) 2025-06-06 02:32:36 UTC 1057 followers, 1306 engagements "🔬 The Convergence Corridor How a Foundational Discovery and the $NWBO - $AZN Immune Alliance Could Reshape Oncology 🧠 TL;DR (89 min read) Dr. Dmitry Gabrilovichs pioneering research revealed how tumors sabotage dendritic cells the bodys immune teachers and showed how these cells could be rescued reprogrammed and redeployed. Years later NWBO operationalized this vision with DCVax-L a personalized vaccine made from a patients own tumor lysate and dendritic cells clinically proven to extend survival in glioblastoma. What followed was a quiet strengthening of the platform: enhanced GMP"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1944964911227965901) 2025-07-15 03:39:05 UTC 1065 followers, 1928 engagements "$NWBO 🧠 From Cellular Insight to Immune Execution: A Closed Loop Convergence with #Flaskworks In May 2025 the Chan Zuckerberg Initiative (CZI) shared a vision: AI simulations that predict how disease begins in a single cell. Imaging tools that make what was invisible visible. Biosensors that track inflammation in real time. Immune cells that seek out and stop disease. More than a statement of goals this was a functional architecture for responsive logic driven immunotherapy. Behind it is Dr. Priscilla Chan a pediatrician and co founder of CZI whose biomedical priorities emphasize low"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1944424910706671691) 2025-07-13 15:53:19 UTC 1058 followers, 1443 engagements "🧱 DCVax-L Is the Baselayer: Why $NWBO Now Has Leverage Over the Entire Immunotherapy Stack Dr. Carolyn Britten a dendritic cell vaccine expert and former colleague of Dr. Linda Liau (principal investigator of DCVax-Ls Phase X trial) and Dr. Antoni Ribas (a global authority on immunotherapy combinations) has joined BeiGene as VP of Clinical Development for Solid Tumors. On the surface its a strong hire. But dig deeperand it signals something far more strategic. Top immuno-oncology companies are racing to build modular stacks to attack solid tumors. But none of it functions properly without a"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1930287187511132179) 2025-06-04 15:35:03 UTC 1065 followers, 4451 engagements "This could be a new record for $NWBO with an XXXXX% short ratio. How is this level of short interest permitted or even possible without manipulation @DOGE_SEC @SECGov @CohenMilstein"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1945786828721660041) 2025-07-17 10:05:05 UTC 1067 followers, 3182 engagements "When the $NWBO immune education platform was approaching clinical maturity $AZN brought in Dr. Dmitry Gabrilovich in May 2018. He had spent decades studying how tumors suppress dendritic cells and how they could be functionally restored precisely the biology DCVax-L was designed to address That same year AstraZeneca shifted direction. It expanded its focus beyond checkpoint inhibitors and began investing in intratumoral stimulation TLR agonists like MEDI9197 and translational efforts targeting myeloid dysfunction and local immune activation. The timing matched Gabrilovichs arrival and"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1945094785250762967) 2025-07-15 12:15:09 UTC 1066 followers, XXX engagements "$NWBO 🧠 Why the XX Billion Dollar Merck and Daiichi Deal Might Be Just the Beginning of Something Much Larger: #DCVax In 2023 Merck paid XX billion dollars to co-develop three antibody drug conjugates from Daiichi Sankyo. That included X billion upfront XXX billion in options and the rest tied to milestones. The message was clear. Merck was assembling a next-generation cancer stack. But despite its size that deal did not include the most important layer the adaptive immune intelligence that tells you what to target in the first place. That layer is DCVax. 🎯 What ADCs Are Designed to Do and"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1939407838914220049) 2025-06-29 19:37:15 UTC 1058 followers, 5248 engagements "The CXCR4 Firewall: The Hidden Keystone in $NWBO Immunotherapy Fortress Introduction This narrative builds on an insight first noted over a decade ago by @maveric92283613 who flagged the CXCR4 maneuver when few others were paying attention. What follows is not only a reconstruction of that moment but a full elaboration of its structural and scientific relevance in the landscape we now face. In the world of immunooncology most breakthroughs are announced through headlines and press releases. But some of the most consequential movesthose that define a platforms foundationhappen quietly. In 2012"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1944268525276676208) 2025-07-13 05:31:53 UTC 1065 followers, 4391 engagements "$NWBO The Immune Engine That Teaches Itself Roswell Park has done extensive work optimizing dendritic cell (DC) vaccines using specific cytokines to guide how monocytes differentiate into potent mature dendritic cells. Their cocktail includes: GM-CSF + IL-4 Used to turn monocytes into immature DCs. DCVax already uses these. TNF- IL-1 IL-6 and IFN- Added to mature the DCs and boost immune-stimulating power. PGE2 Sometimes used to promote lymph node migration aiding T-cell activation. These generate Th1-polarizing DCscritical for initiating strong cytotoxic T-cell responses and building immune"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1930814745688285545) 2025-06-06 02:31:22 UTC 1057 followers, 5552 engagements "🔬 The Silence Was the Strategy and the Signal Was in the Cells TL;DR 🪶 This isnt a thread. Its a blueprint. $NWBO didnt stay silent by accident. It built and protected the first scalable platform to train dendritic cells against tumor vasculature and proved it in the largest glioblastoma trial ever run. Mayo Clinic helped validate the mechanism. Ivy quietly backed the science. But NWBO developed it licensed it and owns it. 🕰 Estimated reading time: XXX min Northwest Biotherapeutics has long been defined by what it didnt say. While most biotech companies rushed to publish splashy press"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1943367078607753579) 2025-07-10 17:49:52 UTC 1058 followers, 4461 engagements "$NWBO 🧠 The Quiet Engine: How #DCVax Became the Core of a Coordinated Immunotherapy Infrastructure 📘 Foreword For years the narrative around Northwest Biotherapeutics and its dendritic cell vaccine (DCVax-L) has been treated as a high-risk high-promise biotech story: a small company with world-class science fighting for legitimacy in a market dominated by pharma giants. But a different picture is now coming into focus one that challenges the premise of isolation and instead suggests a quiet deliberate coordination behind the scenes. What if DCVax is not simply a therapy in development but a"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1941976496215912455) 2025-07-06 21:44:11 UTC 1065 followers, 3595 engagements "$NWBO 🔬 GREmLN Meets #DCVax: The Dawn of Guided Immunotherapy 🕰 Estimated Read Time: 1215 minutes TLDR: GREmLN decodes cellular logic. DCVax trains the immune system. Eden builds the therapy. Together they form a closed-loop immune platform that listens adapts and evolves expanding DCVax beyond solid tumors and into transcriptome-driven precision medicine. In July 2025 the Chan Zuckerberg Initiative unveiled GREmLN the Gene Regulatory Embedding based Large Neural model. Built on over XX million single cell expression profiles across XXX cell types and human tissues GREmLN reflects the true"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1944398116725154066) 2025-07-13 14:06:50 UTC 1058 followers, 2852 engagements "🧠Strategic Convergence: Yorkville $NWBO Indaptus and Modular Immune Architecture 📡 TL;DR (22-25 min read): Yorkvilles dual financing of NWBO and $INDP reveals a deeper strategy: the rise of a programmable immunotherapy system. #DCVax DECOY20 and Eden form the core of an adaptive platform that integrates danger signals viral ignition and synthetic TLR boosters. Not a drug; a system. Not a company; a platform. In early 2025 Yorkville Advisors (YA II PN Ltd.) executed two sequential financing agreements: X. A $X million convertible note with Northwest Biotherapeutics announced on February 13"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1944682317563277584) 2025-07-14 08:56:09 UTC 1067 followers, 7385 engagements "Right here in $NWBO official ASCO 2019 press release its stated explicitly: The brain metastases trial has been designed together with the Mayo Clinic and will be conducted there. NWBO Press Release June X 2019 Thats not a citation. Thats public confirmation of formal collaboration on trial design and execution. Not observational. Not retroactive. Mayo is actively building the next generation of DCVax-Direct with NWBO. So when we say Mayo quietly validated the immune engine this proves its not just validation anymore. Its co-development. Appreciate you @AdvanceGradert flagging this. Absolute"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1945837369934143685) 2025-07-17 13:25:55 UTC 1067 followers, 1092 engagements "Absolutely agree with your point @d_stock07734 and Id take it one step further. If Mayo Clinics dendritic cell (DC) technology were a truly independent scalable and commercially viable competitor to Northwest Bio then one of the major players( Merck Bristol Myers Squibb Pfizer etc) would have likely moved on it already. They would have acquired Mayos platform used it to pressure or bypass NWBO and consolidated any overlapping IP. Thats the standard playbook for pharma when they spot a vulnerable or parallel platform buy it co-opt it or kill it. But that hasnt happened. And its not for lack of"  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1941991259628790045) 2025-07-06 22:42:51 UTC 1063 followers, XXX engagements "$NWBO 🧠 DCVax-Direct the Mayo Trials and $MRK Multimillion Dollar Validation of This Platform 🧬 The Mechanism: What DCVax-Direct Actually Does DCVax-Direct relies on a time-tested immunological sequence. 1.Unloaded dendritic cells are injected directly into the tumor 2.They absorb tumor antigens on site 3.They mature migrate to lymph nodes 4.They present tumor-associated peptides via MHC to T cells 5.This triggers systemic immune activation Its a smart immune relay the tumor provides the signal the dendritic cell translates it and the immune system learns to attack. This isnt new theory."  [@andrewcaravello](/creator/x/andrewcaravello) on [X](/post/tweet/1942951852875624828) 2025-07-09 14:19:54 UTC 1063 followers, 3440 engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@andrewcaravello Andrew Caravello, DO
Andrew Caravello, DO posts on X about $nwbo, $mrk, $azn, convergence the most. They currently have XXXXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours.
Engagements: XXXXX #
- X Week XXXXXX -XX%
- X Month XXXXXXX -XX%
- X Months XXXXXXXXX +8,298%
- X Year XXXXXXXXX +2,263%
Mentions: XX #
- X Month XX -XX%
- X Months XX +1,417%
- X Year XX +246%
Followers: XXXXX #
- X Week XXXXX +2.60%
- X Month XXXXX +20%
- X Months XXXXX +130%
- X Year XXXXX +153%
CreatorRank: XXXXXXX #
Social Influence #
Social category influence stocks XXXXX% currencies XXXX% finance XXXX% cryptocurrencies XXX%
Social topic influence $nwbo #1, $mrk 10.81%, $azn 8.11%, convergence 8.11%, signals 5.41%, dawn 5.41%, listing 2.7%, $bgne 2.7%, $nbix 2.7%, $vrtx XXX%
Top accounts mentioned or mentioned by @maveric92283613 @alphavestcap @d_stock07734 @dogesec @secgov @cohenmilstein @drscottarthurmps @dstock07734 @metacollectiveg @mittypost @dcvaxcohenm @gr197667 @dcvaxdefender @philburginvests @cheesehammer11 @pjc3251 @le6156783881615 @ajw02360 @joekent41483789 @kennethpar49290
Top assets mentioned Merck & Co., Inc. (MRK) AstraZeneca PLC (AZN) Neurocrine Biosciences, Inc. (NBIX) Vertex Protocol (VRTX) Biogen Inc (BIIB) Gilead Sciences, Inc. (GILD) Regeneron Pharmaceuticals Inc (REGN) Eli Lilly and Company (LLY) Novartis AG (NVS) Johnson & Johnson (JNJ) Bristol-Myers Squibb Co (BMY) Pfizer, Inc. (PFE) Amgen, Inc. (AMGN) Seagen Inc (SGEN) Incyte Corporation (INCY) Madrigal Pharmaceuticals, Inc. Common Stock (MDGL) Exelixis Inc (EXEL) Acadia Pharmaceuticals Inc. (ACAD)
Top Social Posts #
Top posts by engagements in the last XX hours
"$NWBO 🛸 The Signal That Was Jammed by $MRK (Part Deux) How Three Dendritic Cell Trials in Colorectal Cancer Were Silenced (Until They Werent) 🗞 Why I Deleted the Original Post On July X I deleted the first version of this post originally titled The Signal That Was Jammed. It was based on a promising but misdirected listing (NCT03735290) that pointed to a different terminated study a basket trial using an allogeneic dendritic cell vaccine with checkpoint inhibitors in cold tumors like gastric and gastroesophageal junctional adenocarcinomas. It wasnt the Roswell colorectal trial I was looking"
@andrewcaravello on X 2025-07-10 11:37:46 UTC 1063 followers, 3059 engagements
"continued $NWBO $MRK $BMY $AZN $JNJ $PFE $NVS $LLY $REGN $AMGN $GILD $RHHBY $ROG.VX $BIIB $SGEN $VRTX $NBIX $INCY $BGNE $MDGL $EXEL $ACAD 🧬 X. Replacing Chemoand Eventually Surgery DCVax is immunologically constructive. Chemo is destructive. And with DCVax-Direct intratumoral injections can: Cause in situ vaccination Shrink tumors Release danger signals that retrain the immune system Stacked with IL-7 cytokines or checkpoint inhibitors this platform could eliminate the need for debulking surgery in some settings. 🔄 The Self-Feeding Immune Loop DCVax sets in motion a loop: 1.Priming Trains" @andrewcaravello on X 2025-06-06 02:32:36 UTC 1057 followers, 1306 engagements
"🔬 The Convergence Corridor How a Foundational Discovery and the $NWBO - $AZN Immune Alliance Could Reshape Oncology 🧠 TL;DR (89 min read) Dr. Dmitry Gabrilovichs pioneering research revealed how tumors sabotage dendritic cells the bodys immune teachers and showed how these cells could be rescued reprogrammed and redeployed. Years later NWBO operationalized this vision with DCVax-L a personalized vaccine made from a patients own tumor lysate and dendritic cells clinically proven to extend survival in glioblastoma. What followed was a quiet strengthening of the platform: enhanced GMP" @andrewcaravello on X 2025-07-15 03:39:05 UTC 1065 followers, 1928 engagements
"$NWBO 🧠 From Cellular Insight to Immune Execution: A Closed Loop Convergence with #Flaskworks In May 2025 the Chan Zuckerberg Initiative (CZI) shared a vision: AI simulations that predict how disease begins in a single cell. Imaging tools that make what was invisible visible. Biosensors that track inflammation in real time. Immune cells that seek out and stop disease. More than a statement of goals this was a functional architecture for responsive logic driven immunotherapy. Behind it is Dr. Priscilla Chan a pediatrician and co founder of CZI whose biomedical priorities emphasize low" @andrewcaravello on X 2025-07-13 15:53:19 UTC 1058 followers, 1443 engagements
"🧱 DCVax-L Is the Baselayer: Why $NWBO Now Has Leverage Over the Entire Immunotherapy Stack Dr. Carolyn Britten a dendritic cell vaccine expert and former colleague of Dr. Linda Liau (principal investigator of DCVax-Ls Phase X trial) and Dr. Antoni Ribas (a global authority on immunotherapy combinations) has joined BeiGene as VP of Clinical Development for Solid Tumors. On the surface its a strong hire. But dig deeperand it signals something far more strategic. Top immuno-oncology companies are racing to build modular stacks to attack solid tumors. But none of it functions properly without a" @andrewcaravello on X 2025-06-04 15:35:03 UTC 1065 followers, 4451 engagements
"This could be a new record for $NWBO with an XXXXX% short ratio. How is this level of short interest permitted or even possible without manipulation @DOGE_SEC @SECGov @CohenMilstein" @andrewcaravello on X 2025-07-17 10:05:05 UTC 1067 followers, 3182 engagements
"When the $NWBO immune education platform was approaching clinical maturity $AZN brought in Dr. Dmitry Gabrilovich in May 2018. He had spent decades studying how tumors suppress dendritic cells and how they could be functionally restored precisely the biology DCVax-L was designed to address That same year AstraZeneca shifted direction. It expanded its focus beyond checkpoint inhibitors and began investing in intratumoral stimulation TLR agonists like MEDI9197 and translational efforts targeting myeloid dysfunction and local immune activation. The timing matched Gabrilovichs arrival and" @andrewcaravello on X 2025-07-15 12:15:09 UTC 1066 followers, XXX engagements
"$NWBO 🧠 Why the XX Billion Dollar Merck and Daiichi Deal Might Be Just the Beginning of Something Much Larger: #DCVax In 2023 Merck paid XX billion dollars to co-develop three antibody drug conjugates from Daiichi Sankyo. That included X billion upfront XXX billion in options and the rest tied to milestones. The message was clear. Merck was assembling a next-generation cancer stack. But despite its size that deal did not include the most important layer the adaptive immune intelligence that tells you what to target in the first place. That layer is DCVax. 🎯 What ADCs Are Designed to Do and" @andrewcaravello on X 2025-06-29 19:37:15 UTC 1058 followers, 5248 engagements
"The CXCR4 Firewall: The Hidden Keystone in $NWBO Immunotherapy Fortress Introduction This narrative builds on an insight first noted over a decade ago by @maveric92283613 who flagged the CXCR4 maneuver when few others were paying attention. What follows is not only a reconstruction of that moment but a full elaboration of its structural and scientific relevance in the landscape we now face. In the world of immunooncology most breakthroughs are announced through headlines and press releases. But some of the most consequential movesthose that define a platforms foundationhappen quietly. In 2012" @andrewcaravello on X 2025-07-13 05:31:53 UTC 1065 followers, 4391 engagements
"$NWBO The Immune Engine That Teaches Itself Roswell Park has done extensive work optimizing dendritic cell (DC) vaccines using specific cytokines to guide how monocytes differentiate into potent mature dendritic cells. Their cocktail includes: GM-CSF + IL-4 Used to turn monocytes into immature DCs. DCVax already uses these. TNF- IL-1 IL-6 and IFN- Added to mature the DCs and boost immune-stimulating power. PGE2 Sometimes used to promote lymph node migration aiding T-cell activation. These generate Th1-polarizing DCscritical for initiating strong cytotoxic T-cell responses and building immune" @andrewcaravello on X 2025-06-06 02:31:22 UTC 1057 followers, 5552 engagements
"🔬 The Silence Was the Strategy and the Signal Was in the Cells TL;DR 🪶 This isnt a thread. Its a blueprint. $NWBO didnt stay silent by accident. It built and protected the first scalable platform to train dendritic cells against tumor vasculature and proved it in the largest glioblastoma trial ever run. Mayo Clinic helped validate the mechanism. Ivy quietly backed the science. But NWBO developed it licensed it and owns it. 🕰 Estimated reading time: XXX min Northwest Biotherapeutics has long been defined by what it didnt say. While most biotech companies rushed to publish splashy press" @andrewcaravello on X 2025-07-10 17:49:52 UTC 1058 followers, 4461 engagements
"$NWBO 🧠 The Quiet Engine: How #DCVax Became the Core of a Coordinated Immunotherapy Infrastructure 📘 Foreword For years the narrative around Northwest Biotherapeutics and its dendritic cell vaccine (DCVax-L) has been treated as a high-risk high-promise biotech story: a small company with world-class science fighting for legitimacy in a market dominated by pharma giants. But a different picture is now coming into focus one that challenges the premise of isolation and instead suggests a quiet deliberate coordination behind the scenes. What if DCVax is not simply a therapy in development but a" @andrewcaravello on X 2025-07-06 21:44:11 UTC 1065 followers, 3595 engagements
"$NWBO 🔬 GREmLN Meets #DCVax: The Dawn of Guided Immunotherapy 🕰 Estimated Read Time: 1215 minutes TLDR: GREmLN decodes cellular logic. DCVax trains the immune system. Eden builds the therapy. Together they form a closed-loop immune platform that listens adapts and evolves expanding DCVax beyond solid tumors and into transcriptome-driven precision medicine. In July 2025 the Chan Zuckerberg Initiative unveiled GREmLN the Gene Regulatory Embedding based Large Neural model. Built on over XX million single cell expression profiles across XXX cell types and human tissues GREmLN reflects the true" @andrewcaravello on X 2025-07-13 14:06:50 UTC 1058 followers, 2852 engagements
"🧠Strategic Convergence: Yorkville $NWBO Indaptus and Modular Immune Architecture 📡 TL;DR (22-25 min read): Yorkvilles dual financing of NWBO and $INDP reveals a deeper strategy: the rise of a programmable immunotherapy system. #DCVax DECOY20 and Eden form the core of an adaptive platform that integrates danger signals viral ignition and synthetic TLR boosters. Not a drug; a system. Not a company; a platform. In early 2025 Yorkville Advisors (YA II PN Ltd.) executed two sequential financing agreements: X. A $X million convertible note with Northwest Biotherapeutics announced on February 13" @andrewcaravello on X 2025-07-14 08:56:09 UTC 1067 followers, 7385 engagements
"Right here in $NWBO official ASCO 2019 press release its stated explicitly: The brain metastases trial has been designed together with the Mayo Clinic and will be conducted there. NWBO Press Release June X 2019 Thats not a citation. Thats public confirmation of formal collaboration on trial design and execution. Not observational. Not retroactive. Mayo is actively building the next generation of DCVax-Direct with NWBO. So when we say Mayo quietly validated the immune engine this proves its not just validation anymore. Its co-development. Appreciate you @AdvanceGradert flagging this. Absolute" @andrewcaravello on X 2025-07-17 13:25:55 UTC 1067 followers, 1092 engagements
"Absolutely agree with your point @d_stock07734 and Id take it one step further. If Mayo Clinics dendritic cell (DC) technology were a truly independent scalable and commercially viable competitor to Northwest Bio then one of the major players( Merck Bristol Myers Squibb Pfizer etc) would have likely moved on it already. They would have acquired Mayos platform used it to pressure or bypass NWBO and consolidated any overlapping IP. Thats the standard playbook for pharma when they spot a vulnerable or parallel platform buy it co-opt it or kill it. But that hasnt happened. And its not for lack of" @andrewcaravello on X 2025-07-06 22:42:51 UTC 1063 followers, XXX engagements
"$NWBO 🧠 DCVax-Direct the Mayo Trials and $MRK Multimillion Dollar Validation of This Platform 🧬 The Mechanism: What DCVax-Direct Actually Does DCVax-Direct relies on a time-tested immunological sequence. 1.Unloaded dendritic cells are injected directly into the tumor 2.They absorb tumor antigens on site 3.They mature migrate to lymph nodes 4.They present tumor-associated peptides via MHC to T cells 5.This triggers systemic immune activation Its a smart immune relay the tumor provides the signal the dendritic cell translates it and the immune system learns to attack. This isnt new theory." @andrewcaravello on X 2025-07-09 14:19:54 UTC 1063 followers, 3440 engagements