# ![@Skinfolder Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::1922420367819202561.png) @Skinfolder Daniella

Daniella posts on X about skin, food, if you, health the most. They currently have [---] followers and [--] posts still getting attention that total [------] engagements in the last [--] hours.

### Engagements: [------] [#](/creator/twitter::1922420367819202561/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::1922420367819202561/c:line/m:interactions.svg)

- [--] Week [------] +60%
- [--] Month [------] +89%

### Mentions: [--] [#](/creator/twitter::1922420367819202561/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::1922420367819202561/c:line/m:posts_active.svg)


### Followers: [---] [#](/creator/twitter::1922420367819202561/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::1922420367819202561/c:line/m:followers.svg)

- [--] Week [---] +26%
- [--] Month [---] +406%

### CreatorRank: [-------] [#](/creator/twitter::1922420367819202561/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::1922420367819202561/c:line/m:influencer_rank.svg)

### Social Influence

**Social category influence**
[finance](/list/finance)  8.86% [currencies](/list/currencies)  3.8% [technology brands](/list/technology-brands)  2.53% [countries](/list/countries)  1.27% [travel destinations](/list/travel-destinations)  1.27%

**Social topic influence**
[skin](/topic/skin) 10.13%, [food](/topic/food) 6.33%, [if you](/topic/if-you) 6.33%, [health](/topic/health) 6.33%, [theory](/topic/theory) 3.8%, [in the](/topic/in-the) 3.8%, [science](/topic/science) 2.53%, [the most](/topic/the-most) 2.53%, [growth](/topic/growth) 2.53%, [events](/topic/events) 2.53%

**Top accounts mentioned or mentioned by**
[@lindsay14769520](/creator/undefined) [@drericberg](/creator/undefined) [@baileybillyb](/creator/undefined) [@alpacaaurelius](/creator/undefined) [@mkmlee](/creator/undefined) [@rainmaker1973](/creator/undefined) [@iterintellectus](/creator/undefined) [@frontrangepaws](/creator/undefined) [@soveyx](/creator/undefined) [@notyourpleaser](/creator/undefined) [@iloveveganpvssy](/creator/undefined) [@bowtiedum](/creator/undefined) [@hakk236728](/creator/undefined) [@_christinaward](/creator/undefined) [@m_kmlee](/creator/undefined)
### Top Social Posts
Top posts by engagements in the last [--] hours

"True. The liver doesn't have pain receptors so by the time you feel something dysfunction is significant. Those symptoms come from liver enlargement (hepatomegaly) putting pressure on surrounding structures and referred pain patterns. When your liver is congested with fat inflamed or struggling to process toxins it swells. This pushes against the diaphragm and rib cage - that's the right-side tightness and shoulder pain (referred via phrenic nerve). Bloating happens because bile production and flow are compromised which wrecks fat digestion and causes gas buildup. Other overlooked liver"  
[X Link](https://x.com/Skinfolder/status/2021219069710512161)  2026-02-10T13:45Z [---] followers, [---] engagements


"Longevity influencers bombarding themselves with botox and recommending bogus supplements. When they ACTIVELY do those things and seem to age faster don't fool yourself - It's not the quest to beat aging. It's a quest to make money from ridiculous treatments"  
[X Link](https://x.com/Skinfolder/status/2021415148246966303)  2026-02-11T02:45Z [---] followers, [--] engagements


"Most "natural" supplements don't move the needle on actual insulin resistance. BERBERINE DOES. An umbrella meta-analysis of [--] meta-analyses (covering thousands of patients in randomized controlled trials) shows berberine significantly lowers fasting glucose HbA1c insulin resistance and multiple inflammatory markers. The mechanism isn't single-target like metformin - it's coordinating metabolic improvements across liver muscle pancreas gut and adipose tissue simultaneously. https://twitter.com/i/web/status/2021429764129497529 https://twitter.com/i/web/status/2021429764129497529"  
[X Link](https://x.com/Skinfolder/status/2021429764129497529)  2026-02-11T03:43Z [---] followers, [---] engagements


"The path to truth is more ruthless than the path to delusion. Delusion lets you follow the crowd trust authority figures and avoid the cognitive load of evaluating evidence yourself. Truth demands you question narratives even when it's socially costly. Take the vaccine example The comfortable path: "Experts say it's safe and effective the CDC recommends it everyone's doing it case closed." You get social approval you're "following the science" and you don't have to think hard"  
[X Link](https://x.com/Skinfolder/status/2021441459258368393)  2026-02-11T04:29Z [---] followers, [--] engagements


"The ruthless path: read the actual clinical trial data not the press releases. Notice the endpoints were relative risk reduction not absolute. Check who funded the studies. Look at adverse event reporting systems. Examine the conflicts of interest in regulatory agencies where officials rotate between pharma companies and approval boards. Ask why liability was waived. Question why we're calling something "safe and effective" when long-term data doesn't exist yet. https://twitter.com/i/web/status/2021441671695605963 https://twitter.com/i/web/status/2021441671695605963"  
[X Link](https://x.com/Skinfolder/status/2021441671695605963)  2026-02-11T04:30Z [---] followers, [--] engagements


"But truth doesn't care about comfort. It doesn't care if questioning the narrative costs you relationships or makes you an outcast. The institutions telling you to "trust the science" have lied before - tobacco opioids sugar vs fat. Believing them without scrutiny isn't rationality it's obedience. https://twitter.com/i/web/status/2021442326917169454 https://twitter.com/i/web/status/2021442326917169454"  
[X Link](https://x.com/Skinfolder/status/2021442326917169454)  2026-02-11T04:33Z [---] followers, [--] engagements


"Vitamin A (retinol not beta-carotene) is the most underrated. Your mucosal barriers- respiratory tract gut lining urogenital tract - are your first line of defense. Before anything gets to your immune cells it has to cross mucosa. Vitamin A maintains the integrity of these barriers by regulating epithelial cell differentiation and mucus production. Without adequate retinol your barriers break down and pathogens walk right in. Vitamin A also directly regulates T-cell differentiation. Retinoic acid (active form of vitamin A) determines whether naive T-cells become regulatory T-cells (Tregs) or"  
[X Link](https://x.com/Skinfolder/status/2021590802669965582)  2026-02-11T14:23Z [---] followers, [---] engagements


"The bigger issue nobody talks about - mycotoxins. Ochratoxin A and aflatoxin B1 from mold contamination during storage - both classified as potential carcinogens. These survive processing far better than pesticides do. Decaf is even worse because caffeine naturally inhibits mold growth and the chemical decaffeination process (methylene chloride) adds another layer of exposure. So the real protocol: organic wet-processed whole bean (less surface area for mold) dark roast (higher thermal degradation) and drink it black or with grass-fed butter/ghee. Skip anything from bulk commodity sources in"  
[X Link](https://x.com/Skinfolder/status/2021604819350225085)  2026-02-11T15:18Z [---] followers, [----] engagements


"@m_kmlee @dr_ericberg Not a coffee drinker myself but some of my clients enjoy Kion coffee which looks quite safe. Lifeboost coffee also seems great in theory but i don't know enough about them to give a clear recommendation"  
[X Link](https://x.com/Skinfolder/status/2021614162867040354)  2026-02-11T15:55Z [---] followers, [---] engagements


"The ER in my area is filled with people below the age of [--] stroke and heart events. Till [--] years ago I didn't know anyone below the age of [--] that even had a stroke. We know why and most of the ways they're doing it to us but this shit must he stopped. Hijacking our bodies one after one. https://twitter.com/i/web/status/2021618991307862231 https://twitter.com/i/web/status/2021618991307862231"  
[X Link](https://x.com/Skinfolder/status/2021618991307862231)  2026-02-11T16:15Z [---] followers, [--] engagements


"@Baileybillyb @dr_ericberg Sure Wrote it on another comment to someone else that asked check it out"  
[X Link](https://x.com/Skinfolder/status/2021625838744342606)  2026-02-11T16:42Z [---] followers, [--] engagements


"Appreciate it 🤣🤣 The best incentive to solve a problem is to have it I have higher glutamate than normal so any misalignment whether its covid or just a sleepless night is slightly felt. Magnesium agmatine and a lot of sun will improve most glutamate(AMPA) dyregulation cases. @Skinfolder @Rainmaker1973 https://t.co/zabsvOgh3w @Skinfolder @Rainmaker1973 https://t.co/zabsvOgh3w"  
[X Link](https://x.com/Skinfolder/status/2021674365436223810)  2026-02-11T19:55Z [---] followers, [---] engagements


"Good explanation. The part that makes this so terrifying is where the damage happens. It's almost always the brainstem - the tiny bridge between your brain and your body. Everything above it still works perfectly. You think you feel you understand. But every signal your brain sends to move speak or breathe gets cut off right at that bridge. Most cases come from a stroke hitting the pons - a specific part of the brainstem that carries all motor commands from brain to body. The eye movement survives because those nerve pathways run through a slightly different route. Some people have"  
[X Link](https://x.com/Skinfolder/status/2021906227681272003)  2026-02-12T11:16Z [---] followers, [---] engagements


"The engineering is real but the markup is the bigger story. The same stent that costs $120 in Germany costs $670+ in the US before you even factor in hospital fees. What nobody tells you after getting one: the stent isn't a fix it's a bridge. The artery clogged once and it can - again. Restenosis - re-narrowing inside the stent - happens in 10-20% of cases within the first year. What actually matters post-stent: don't skip the blood thinners. Dual antiplatelet therapy (usually aspirin + clopidogrel) for at least 6-12 months prevents clots forming on the stent's metal surface before your"  
[X Link](https://x.com/Skinfolder/status/2021927802266644755)  2026-02-12T12:42Z [---] followers, [--] engagements


"Balding ISN'T a sign of "high DHT." This is backwards. Systemic DHT levels don't correlate well with hair loss - plenty of guys with sky-high DHT have full heads of hair. The real issue is local scalp environment. When blood flow to the scalp drops (chronic tension in the galea aponeurotica sedentary lifestyle poor posture) you get reduced oxygen and nutrient delivery to follicles. That hypoxic environment upregulates local 5-alpha reductase activity - converting more testosterone to DHT right at the follicle and in general less estrogen at most of the scalp. The causal chain: poor scalp"  
[X Link](https://x.com/Skinfolder/status/2022733393490837591)  2026-02-14T18:03Z [---] followers, 10.9K engagements


"Solid base - mix it with pumpkin seed oil and you get a synergistic effect most people don't know about - pumpkin seed oil inhibits 5-alpha reductase locally at the scalp reducing DHT conversion right where it matters without nuking your hormones systemically. Combined with castor oil's ricinoleic acid - which is a potent anti-inflammatory that increases prostaglandin E2 at the follicle - you're simultaneously halting miniaturization deepening the follicle root and increasing blood flow to the dermal papilla. That's the trifecta: lower local DHT reduced inflammation better perfusion. Add a"  
[X Link](https://x.com/Skinfolder/status/2022829797936660780)  2026-02-15T00:26Z [---] followers, [----] engagements


"Spot on. The cholesterol-heart disease narrative has been one of the most profitable mistakes in medical history. LDL alone tells you almost nothing - what matters is whether it's oxidized and what's causing the oxidation. Processed oils chronic inflammation insulin resistance - those are the drivers of arterial damage not the cholesterol trying to repair it. Blaming cholesterol for heart disease is like blaming firefighters for the fire because they keep showing up at burning buildings. Statins lower the number on the lab sheet while doing nothing about the oxidative environment that made"  
[X Link](https://x.com/Skinfolder/status/2022831917431713798)  2026-02-15T00:34Z [---] followers, [---] engagements


"@lindsay14769520 @dr_ericberg Happy to hear that Did you have very obvious deficencies And also tried to do a thyroid panel"  
[X Link](https://x.com/Skinfolder/status/2022843720664531131)  2026-02-15T01:21Z [---] followers, [--] engagements


"Jawline and chin acne This is hormonal. Menstrual cycle fluctuations blood sugar crashes PCOS or androgen imbalance. If it's cyclical it's your hormones"  
[X Link](https://x.com/Skinfolder/status/2007929445680837042)  2026-01-04T21:37Z [--] followers, [--] engagements


"Neck and chest breakouts Sweat friction product overflow. Sports bras perfume hair oils sitting on your skin not washing off sunscreen or makeup at night"  
[X Link](https://x.com/Skinfolder/status/2007929517776711764)  2026-01-04T21:37Z [--] followers, [--] engagements


"99% of people using "acne oils" are making their skin worse. Here's how to actually use them:"  
[X Link](https://x.com/Skinfolder/status/2007960979280400874)  2026-01-04T23:42Z [--] followers, [--] engagements


"My skin was a disaster always dry. Tried everything - creams antibiotics cutting dairy cutting sugar. Nothing worked"  
[X Link](https://x.com/Skinfolder/status/2008156157555417367)  2026-01-05T12:38Z [--] followers, [--] engagements


"Then I read studies about Vitamin A deficiency and dryness+acne. Started eating liver twice a week. Cleared in [--] weeks. Not because the other stuff was wrong - because I was missing one critical piece. Most "solutions" are just noise when you haven't fixed the foundation"  
[X Link](https://x.com/Skinfolder/status/2008156326531305498)  2026-01-05T12:39Z [--] followers, [--] engagements


"Respect your body. Respect your time. Respect your goals. Spend time with family. Get sunlight daily. Eat nutrient-dense food. Move with purpose. Everything else becomes easier when your basics are dialed in"  
[X Link](https://x.com/Skinfolder/status/2008622356273786901)  2026-01-06T19:31Z [--] followers, [--] engagements


"B1 raised my baseline energy and it actually stuck - even after I dropped the dose way down. I was running high-dose thiamine and honestly the changes were pretty wild. Energy baseline just went up and stayed there. It's not like caffeine where you crash after it's a real lasting change. Mental endurance got way better too. Could focus for hours without feeling completely fried. Memory retrieval improved a lot which was unexpected but probably the biggest mental shift I noticed. The skin stuff though literally nobody talks about this and it's a shame. My skin got way less reactive. After"  
[X Link](https://x.com/Skinfolder/status/2008650790706012489)  2026-01-06T21:24Z [--] followers, [--] engagements


"GPT nutritionists will tell you to eat chicken breast brown rice and steamed broccoli for "glowing skin" then wonder why you look like a corpse after [--] months. Your skin needs fat-soluble vitamins (A D E K) cholesterol for hormone production and collagen from actual animal products"  
[X Link](https://x.com/Skinfolder/status/2008730608701170028)  2026-01-07T02:41Z [--] followers, [--] engagements


"Lean protein and vegetables won't do much for your skin. You need: - Egg yolks - Butter - Liver - Bone broth - Fatty fish But ChatGPT will keep recommending you eat like a bodybuilder from [----] and expect results. Your skin is made of fat and protein. Feed it accordingly"  
[X Link](https://x.com/Skinfolder/status/2008730902416027699)  2026-01-07T02:42Z [--] followers, [--] engagements


"Another big one: chronic inflammation. Inflammation keeps you holding water weight drives insulin and leptin resistance and suppresses thyroid function. Even in a calorie deficit weight loss will stall when inflammation has hijacked your hormones. Common culprits: Processed oils poor sleep gut issues chronic stress high sugar. You can be doing everything right on paper but if inflammation is high the scale won't move and your hormones won't allow fat burning. Fix inflammation first then fat loss actually becomes possible. https://twitter.com/i/web/status/2009994683271794927"  
[X Link](https://x.com/Skinfolder/status/2009994683271794927)  2026-01-10T14:24Z [--] followers, [---] engagements


"Premature skin aging and poor wound healing are huge warning signs most people ignore. Collagen breakdown thin skin that bruises easily slow healing - all signs of Vitamin C copper or protein deficiency or insulin resistance. Your face shows internal problems before blood tests do. https://twitter.com/i/web/status/2010131726996000909 https://twitter.com/i/web/status/2010131726996000909"  
[X Link](https://x.com/Skinfolder/status/2010131726996000909)  2026-01-10T23:28Z [--] followers, [---] engagements


"Key thing to miss any of these works significantly better if your baseline inflammation is controlled. High sugar diet processed oils chronic stress poor sleep - all of these block the benefits of vitamin D omega-3s and red light therapy by keeping mitochondria dysfunctional. Fix the damage sources first then optimization actually has ROI. https://twitter.com/i/web/status/2010133118699876557 https://twitter.com/i/web/status/2010133118699876557"  
[X Link](https://x.com/Skinfolder/status/2010133118699876557)  2026-01-10T23:34Z [--] followers, [----] engagements


"Natto is also one of the richest sources of Vitamin K2 (MK-7) which has its own anti-cancer properties. K2 activates matrix Gla-protein (MGP) which prevents calcification and has been shown to suppress tumor growth independently. So you're getting both nattokinase (anti-angiogenic) and K2 (anti-calcification pro-apoptosis in cancer cells) together. Among the many reasons traditional Japanese diets accompany such low cancer rates. https://twitter.com/i/web/status/2010137651127463939 https://twitter.com/i/web/status/2010137651127463939"  
[X Link](https://x.com/Skinfolder/status/2010137651127463939)  2026-01-10T23:52Z [--] followers, [---] engagements


"/4 Heart rhythm destabilizes. Potassium controls electrical signaling in your heart. Deficiency causes irregular heartbeat elevated resting heart rate palpitations and arrhythmias. Many people on heart medications are just severely potassium deficient"  
[X Link](https://x.com/Skinfolder/status/2010747034844999693)  2026-01-12T16:13Z [--] followers, [--] engagements


"/5 Functional strength collapses. Potassium regulates muscle contraction through sodium-potassium pumps. Low potassium means difficulty with stairs trouble getting up from chairs balance problems and progressive weakness. This isn't aging or weakness - it's deficiency"  
[X Link](https://x.com/Skinfolder/status/2010747233793098179)  2026-01-12T16:14Z [--] followers, [--] engagements


"/6 Growth hormone and IGF-1 drop by approxiametly 30%. Needed to repair tissue maintain bone density prevent muscle loss. Potassium deficiency accelerates sarcopenia and slows recovery. Hard to build or maintain muscle without adequate potassium regardless of protein intake"  
[X Link](https://x.com/Skinfolder/status/2010747539943735410)  2026-01-12T16:15Z [--] followers, [--] engagements


"/7 Muscle hydration fails. Potassium pulls water into muscle cells. Low potassium causes muscle dehydration while water accumulates outside cells as bloating. Result: weak muscles AND water retention simultaneously"  
[X Link](https://x.com/Skinfolder/status/2010747682017759728)  2026-01-12T16:16Z [--] followers, [--] engagements


"@AlpacaAurelius Unironically effective. Tryptophan calcium and fat. Together they stabilize blood sugar overnight and support melatonin production. Hard cheeses work best for me - cheddar parmesan aged gouda. Avoid processed cheese and aged if you have histamine issues"  
[X Link](https://x.com/Skinfolder/status/2010750039782465724)  2026-01-12T16:25Z [--] followers, [---] engagements


"@IterIntellectus Im afraid we may have AI-designed proteins and CRISPR therapies for infants while 70% of adults still can't figure out that processed oils and carbs are destroying their metabolism. Programmable biology for the 1% basic nutrition still unsolved for everyone else"  
[X Link](https://x.com/Skinfolder/status/2010812241046597716)  2026-01-12T20:32Z [--] followers, [---] engagements


"The funniest part about flipping the food pyramid is people thinking it represents some breakthrough in nutritional science. No. Institutional shifts don't happen because they discovered the truth. They happen because the lies became too radical to maintain credibility"  
[X Link](https://x.com/Skinfolder/status/2010813335860548006)  2026-01-12T20:37Z [--] followers, [--] engagements


"When 70% of the population is obese and metabolically broken following your guidelines for [--] years the only chess move left is a controlled pivot and pretending you knew all along"  
[X Link](https://x.com/Skinfolder/status/2010813492169670805)  2026-01-12T20:37Z [--] followers, [--] engagements


"@AlpacaAurelius Turns out sitting in a Herman Miller chair staring at Excel for [--] hours daily is worse for your testosterone than lifting stuff in broad daylight. Who could have predicted this haha"  
[X Link](https://x.com/Skinfolder/status/2010820770285465771)  2026-01-12T21:06Z [--] followers, [---] engagements


"Indeed. Except things that reduce plaque accumulation like shitty oils and refined carbs - the next best thing is to ensure proper mineral status and blood flow. Potassium Magnesium and Vitamin E all lack in our diets and cause more cardiac events than peolle would like to believe. https://twitter.com/i/web/status/2010864914710008004 https://twitter.com/i/web/status/2010864914710008004"  
[X Link](https://x.com/Skinfolder/status/2010864914710008004)  2026-01-13T00:02Z [--] followers, [--] engagements


"Most people are SEVERLY choline deficient and don't realize it's wrecking their brain liver and metabolism. Choline is essential for: - Acetylcholine production (focus memory learning) - Hippocampus development (long-term memory formation) - Neurotransmitter balance (mood regulation emotional stability) - Liver fat metabolism (prevents fatty liver) - Cell membrane integrity (brain and body function) Without adequate choline fat accumulates in your liver cognitive function declines and mood destabilizes. Best food sources: - Egg yolks (147mg per egg) - Beef liver (350mg per 3oz) - Salmon (90mg"  
[X Link](https://x.com/Skinfolder/status/2011180232028610790)  2026-01-13T20:55Z [--] followers, [--] engagements


"MY FAVOURITE CHOLINE SUPPLEMENTS (when food isn't enough): CDP-Choline (Citicoline): Best for - general deficiency liver support neuroprotection. Converts to both choline AND uridine (supports brain cell membranes). Highly effective for fatty liver prevention and cognitive enhancement. Great for long-term use. Phosphatidylcholine: Best for - liver health cell membrane repair fat metabolism. Directly provides the form your liver needs to export fat. Excellent for reversing fatty liver. Also supports brain cell membranes. Safe for long-term supplementation. Alpha-GPC: Best for - acute cognitive"  
[X Link](https://x.com/Skinfolder/status/2011181246848643078)  2026-01-13T20:59Z [--] followers, [--] engagements


"Excellent breakdown. The liver-blood sugar isn't being talked about enough. Fixing gut health stabilized my blood sugar better than any dietary intervention. No more afternoon crashes no more waking up at 3am with adrenaline surges. The gut-liver-stress axis is real and most people have no idea it's driving their anxiety. https://twitter.com/i/web/status/2011451256967938367 https://twitter.com/i/web/status/2011451256967938367"  
[X Link](https://x.com/Skinfolder/status/2011451256967938367)  2026-01-14T14:52Z [--] followers, [---] engagements


"Important to make the BEST from sulforaphane- it needs the enzyme myrosinase to activate. Lightly steaming or eating raw preserves myrosinase. Overcooking destroys it. Broccoli sprouts have 10-100x more sulforaphane than mature broccoli. Easy to grow at home for pennies. Add mustard powder when cooking to restore myrosinase if you prefer cooked vegetables. https://twitter.com/i/web/status/2011577911166279817 https://twitter.com/i/web/status/2011577911166279817"  
[X Link](https://x.com/Skinfolder/status/2011577911166279817)  2026-01-14T23:15Z [--] followers, [---] engagements


"The most insteresting part is that the organs aging first (heart kidneys liver) are your highest metabolic rate tissues. They're getting hammered by oxidative stress and glycation earliest. Protecting mitochondrial function and keeping metabolic health at it's peak espescially before reaching 30's will propel slower aging trajectory although it's never too late to fix it. https://twitter.com/i/web/status/2011827577866920295 https://twitter.com/i/web/status/2011827577866920295"  
[X Link](https://x.com/Skinfolder/status/2011827577866920295)  2026-01-15T15:47Z [--] followers, [---] engagements


"Before doing it make sure you understand WHICH TYPE of tumor you have and the metabolic pathways to it. Some tumors actually thrive on ketones more than on sugar which is the dangerous part and then metabolic understanding may be the key to unlock healing from another direction even. If your tumor feeds on sugar or even on ketones+sugar I really saw some interesting results with fasting and it's worth investigating. Always make sure to understand your cancer type AS MUCH AS YOU can before going either way"  
[X Link](https://x.com/Skinfolder/status/2011828632411570251)  2026-01-15T15:51Z [--] followers, 15K engagements


"The problem is that niacin deficiency mimics a dozen other conditions. Fatigue = "stress" brain fog = "aging" skin issues = "eczema." Meanwhile it's just inadequate NAD+ production affecting every metabolic pathway. EVEN WORSE: high-carb diets require MORE niacin for glucose metabolism while providing less (no tryptophan from protein). Easy to test though some portions of muscle meat can help identify B3 deficency and then temporary focus on muscle meats and targeted supplementaion will resolve it in no-time. https://twitter.com/i/web/status/2012236656548401606"  
[X Link](https://x.com/Skinfolder/status/2012236656548401606)  2026-01-16T18:52Z [--] followers, [---] engagements


"You can't just avoid fructose - you need to get rid of the stored fat. Caloric deficit + resistance training (improves hepatic insulin sensitivity) high protein (prevents muscle loss during fat loss) and also sufficient carbs and fats for insulin sensitivity maintenance and hormonal production. Choline supplementation 500-700mg or eat 3-4 eggs daily (required for fat export from liver). Track progress with liver enzymes not just weight. https://twitter.com/i/web/status/2012326266276294941 https://twitter.com/i/web/status/2012326266276294941"  
[X Link](https://x.com/Skinfolder/status/2012326266276294941)  2026-01-17T00:49Z [--] followers, [---] engagements


"For mechanical and internal support also worth trying - Elevate legs for [--] min a few times daily. Walk regularly. Walking does two things - activates your calf muscle pump and triggers angiogenesis (your body forms new blood vessels to create alternate routes). This is huge for long-term circulation improvement. Horse chestnut extract 300mg 2x daily actually has solid clinical data for reducing swelling and heaviness. https://twitter.com/i/web/status/2012329130591739924 https://twitter.com/i/web/status/2012329130591739924"  
[X Link](https://x.com/Skinfolder/status/2012329130591739924)  2026-01-17T01:00Z [--] followers, [---] engagements


"- Grip strength: can hang from pull-up bar 40+ seconds - Body temperature stable 97.8-98.6F (good thyroid) - Breath hold after normal exhale: 40+ seconds (CO2 tolerance) - Wounds close within 3-5 days (protein synthesis working) - Nails grow fast and strong (mineral status is good) https://twitter.com/i/web/status/2012507275911418054 https://twitter.com/i/web/status/2012507275911418054"  
[X Link](https://x.com/Skinfolder/status/2012507275911418054)  2026-01-17T12:48Z [--] followers, [---] engagements


"Most of these come down to one thing: your liver can't process fat properly. When fat metabolism breaks you can't absorb vitamins A and E (chicken skin) can't clear estrogen (spider veins red palms) and lipids get deposited wrong (cholesterol around eyes). Main culprits: choline deficiency insulin resistance seed oils oxidizing in liver tissue. Fix it by eating 3-4 eggs daily bitter foods for bile (coffee arugula) resistance training cut seed oils. These aren't separate issues. They're all pointing to broken liver fat metabolism. https://twitter.com/i/web/status/2012668231803101677"  
[X Link](https://x.com/Skinfolder/status/2012668231803101677)  2026-01-17T23:27Z [--] followers, [----] engagements


"Capsaicin is solid for inflammation but there's a massive difference depending on the source: - Paprika: 0.01-0.3% (negligible) - Cayenne: 0.1-0.5% (effective) - Jalapeos: 0.03% (moderate) - Habanero: 0.8-1.5% (high) Effective anti-inflammatory dose is 5-10mg/day capsaicin. Practical ways to get it: - Two 500mg cayenne capsules (40000 SHU standard) - 1/2 tsp cayenne powder in meals Fresh hot peppers with lunch/dinner - Capsaicin extract (10mg) Builds heat tolerance fast - start low. Also increases metabolism improves circulation may help insulin sensitivity. Paprika is fine for cooking and"  
[X Link](https://x.com/Skinfolder/status/2013378865414955310)  2026-01-19T22:31Z [--] followers, [--] engagements


"Puzzle for centuries Your grandpa used to sit with MyFitnessPal It all started with the normalization of those fake fats and carbs. Just eat real foods eat eggs potatoes meat fruits seafood squashes milk real foods. You'll never be protein deficient you will have normal hunger signals you'll feel what you need. https://twitter.com/i/web/status/2013684513759486086 https://twitter.com/i/web/status/2013684513759486086"  
[X Link](https://x.com/Skinfolder/status/2013684513759486086)  2026-01-20T18:46Z [--] followers, [---] engagements


"Food wayyy less oxidized. Most omega-3 supplements arrive already oxidized from heat light and oxygen during processing. If your fish oil burps taste rancid it's oxidized - you're consuming lipid peroxides which is inflammatory. Whole fish like salmon sardines mackerel and cod protect omega-3s naturally. Plus you get vitamin D selenium B12 iodine. Cod liver is especially good - high EPA/DHA plus vitamins A and D. The real issue isn't omega-3 deficiency it's omega-6 overload. The average person the ratio of 20:1 due yo processed oils when it should 3:1 ideally."  
[X Link](https://x.com/Skinfolder/status/2013733509534249102)  2026-01-20T22:00Z [--] followers, [---] engagements


"@frontrangepaws gave great recommendations for general health but regarding O3 intake the form of O3 in plants (alpha linoleic acid) isn't absorbed nearly as well. I would aspire to get shellfish when getting fish isnt possible (oysters mussels shrimps squid). If even that isn't possible by all means aspire to get some plant form O3 (Chiaflax and hemp are all good indeed) and try to find a source of O3 supplement that shows proof of oxidation markers and keeps the product refrigerated. I know in some areas fish are very expensive most of my clients that have tight budget were able to locate a"  
[X Link](https://x.com/Skinfolder/status/2013778325886402798)  2026-01-21T00:59Z [--] followers, [--] engagements


"Nutrition matters but the puberty timing piece is what most people miss. Early puberty = shorter final height but higher bone density. Late puberty = taller final height but lower bone density. The trade-off is controlled by estrogen timing. Bone age X-rays are supposedly the "gold standard" for predicting growth potential but they're not that accurate. Estrogen peak dictates growth plate fusion way more than bone age. This is why girls stop growing around 14-15 despite sometimes having "younger" bone ages - the estrogen surge closes the plates. High estrogen = earlier fusion = less height"  
[X Link](https://x.com/Skinfolder/status/2013987515850522957)  2026-01-21T14:50Z [--] followers, [---] engagements


"Metformin is prescribed LIKE CANDY for longevity and metabolic health but nobody talks about the longevity long term damage it causes. Here's what actually happens when you take it long-term: Metformin inhibits Complex I of the mitochondrial electron transport chain. This directly reduces NAD+ regeneration by blocking the conversion of NADH back to NAD+. Lower NAD+ means impaired mitochondrial function reduced ATP production and accelerated cellular aging. You're literally taking a "longevity drug" that ages your cells faster at the mitochondrial level. This pushes longevity "experts" to take"  
[X Link](https://x.com/Skinfolder/status/2013992578937425979)  2026-01-21T15:10Z [--] followers, [--] engagements


"AI is an accelerator in biology LLMs can help you map pathways tools like claude skills and NotebookLM can help you archive important pieces of information. Heck I even use claude code to build big files that look like crime sketchbooks mapping over time the pathways to every disease. Never let it replace your critical thinking or writing every source and every word should be your choice. This is what our goal is about after all. https://twitter.com/i/web/status/2014132811599417353 https://twitter.com/i/web/status/2014132811599417353"  
[X Link](https://x.com/Skinfolder/status/2014132811599417353)  2026-01-22T00:27Z [--] followers, [--] engagements


"Taking metformin for longevity is PEAK IRONY. You're inhibiting NAD+ (mitochondrial function) muscular function and blocking B12 absorption - all just to activate AMPK and get higher insulin sensitivity which simple herbs can do more effectively with minimum side effects"  
[X Link](https://x.com/Skinfolder/status/2014138041594483159)  2026-01-22T00:48Z [--] followers, [--] engagements


"@SoveyX You can sleep quietly. It'll never happen. Universal high income is a very obvious communism synonym. Our sleep should be bothered from how they'll reach this point and the price we will pay for it"  
[X Link](https://x.com/Skinfolder/status/2014149909889331246)  2026-01-22T01:35Z [--] followers, [--] engagements


"Most of it honestly. The "low serotonin causes depression" theory hold any merit - it was pharmaceutical marketing that became accepted as fact. The reason is quite interesting - When you force serotonin to stay in the synapse longer by blocking reuptake it activates specific serotonin receptors (particularly 5-HT1A) that trigger BDNF release. (BDNF and other growth factors can be induced in much better much lower risk ways) Here's the conflation problem: when researchers measure serotonin in depression studies they're usually measuring blood/platelet serotonin or metabolites in urine/CSF."  
[X Link](https://x.com/Skinfolder/status/2014435963770941555)  2026-01-22T20:32Z [--] followers, [--] engagements


"/4 The "evidence" for the serotonin theory was mostly backwards reasoning: SSRIs increase serotonin signaling and sometimes help depression therefore depression must be from low serotonin. That's like saying headaches are caused by aspirin deficiency"  
[X Link](https://x.com/Skinfolder/status/2014464943773380703)  2026-01-22T22:27Z [--] followers, [--] engagements


"/5 SSRIs do work for some people but probably not through the mechanism we think. The therapeutic effect comes from downstream BDNF upregulation and neurogenesis in the hippocampus which takes 2-4 weeks to start and few months to peak"  
[X Link](https://x.com/Skinfolder/status/2014465245981352422)  2026-01-22T22:28Z [--] followers, [--] engagements


"The thing is - cardio resistance training adequate sleep O3 and even fasting all upregulate BDNF naturally. Of course in depressive states it won't always be enough however there are many interventions and herbal treatments that induce a much stronger neurogensis response"  
[X Link](https://x.com/Skinfolder/status/2014465970203513155)  2026-01-22T22:31Z [--] followers, [--] engagements


"Himalayan pink salt has trace minerals but also trace heavy metals (lead arsenic cadmium) from the ancient seabed it's mined from. Most are below harmful levels but the "mineral-rich" marketing is oversold - you'd need to eat pounds daily to get meaningful mineral intake. Celtic sea salt or Redmond Real Salt are cleaner options. They're harvested from current ocean sources or clean ancient deposits with better mineral profiles and less contamination risk. Honestly though the salt type matters way less than people think. The real benefit of unrefined sea salt over table salt is avoiding"  
[X Link](https://x.com/Skinfolder/status/2014530928379404365)  2026-01-23T02:49Z [--] followers, [---] engagements


"From my personal experience and what I often see with clients sometimes perfect diet misses some parts or alternatively there are very long term-developed issues. Register what you eat for a few days in cronometer see which deficencies you may have developed over time. Both the blood brain barrier and the gut barrier work differently during infancy and are much more permeable dont let it discourage you though most studies are done on people who arent addressing deficiencies and focusing on microbiome health and diversity"  
[X Link](https://x.com/Skinfolder/status/2014797356382765427)  2026-01-23T20:28Z [--] followers, [--] engagements


"Real collagen support comes from boosting your own synthesis. There are few things I like for that - Shilajit: upregulates collagen synthesis genes and dowregulates collagen breakdown genes. Vitamin C: Required for hydroxylating proline and lysine - without it collagen structure literally falls apart. Copper: crosslinks collagen fibers via lysyl oxidase. Without copper the collagen stays weak and breaks down easily. Eat collagen sources (bone broth skin-on chicken) for amino acid building blocks but you need C and copper to actually synthesize and stabilize it. Skip expensive creams fix it"  
[X Link](https://x.com/Skinfolder/status/2016308589732810772)  2026-01-28T00:33Z [--] followers, [---] engagements


"Avenin truly shares structural homology with gliadin which is one of the inflammatory proteins in gluten. In sensitive individuals immune cross-reactivity happens even with gluten-free oats. Some celiacs tolerate oats fine others don't. It depends on which gliadin epitopes your antibodies recognize not every celiac occurrence is the same. The best test is if you have any digestion issues or GI discomfort give up oats for a month and see if you notice any improvement. https://twitter.com/i/web/status/2016596945121276028 https://twitter.com/i/web/status/2016596945121276028"  
[X Link](https://x.com/Skinfolder/status/2016596945121276028)  2026-01-28T19:39Z [--] followers, [---] engagements


"Agree that cooking method matters - high heat creates advanced glycation end products (AGEs) oxidizes fats and produces acrylamide. But you can't separate method from ingredient. Perfectly fried food in fresh tallow is metabolically different than perfectly fried food in soybean oil. One gives you stable saturated fat the other gives you oxidized linoleic acid that embeds in your cell membranes for months. The oil matters as much as the temperature. The hardest part about avoiding fried foods isn't the concept - it's that 95% of fried food is cooked in oxidized fats you can't see or control."  
[X Link](https://x.com/Skinfolder/status/2018362835328172475)  2026-02-02T16:36Z [---] followers, [---] engagements


"Sadly the whole story with L-theronate is classic supplement marketing. Supposedly "crosses the blood-brain barrier" better than other forms. There's one rat study showing this and the supplement industry has turned it into gospel. Here's the reality: all forms of magnesium affect brain function - they just don't need to "cross the blood-brain barrier" in massive amounts to do it. Your brain's magnesium status is tightly regulated. Oral magnesium works on the brain primarily through systemic mechanisms: - Modulating NMDA receptors (peripheral and central) - Regulating neurotransmitter"  
[X Link](https://x.com/Skinfolder/status/2018365579565113594)  2026-02-02T16:47Z [---] followers, [---] engagements


"With SAM-E and B-complex you probably overdosed methyl donors. (Overmethylation does exist and is very common actually). Taurine is usually good as it helps glutamate to gaba balance but seems like you have few imbalances. Indeed focus on the basics first restore deficencies if you has zinc deficnecy you probably have many more. https://twitter.com/i/web/status/2018438724892418389 https://twitter.com/i/web/status/2018438724892418389"  
[X Link](https://x.com/Skinfolder/status/2018438724892418389)  2026-02-02T21:37Z [---] followers, [--] engagements


"True. The fatigue comes first because B12 is essential for methylation and mitochondrial energy production - before you get demyelination and nerve damage your cells just can't make ATP efficiently. You feel exhausted but blood work looks "fine." Standard serum B12 testing is garbage. You can have "normal" B12 (200-300 pg/mL) and still be functionally deficient. Better markers: Methylmalonic acid (MMA) elevated when B12 is actually low at the cellular level. This catches deficiency early. Homocysteine rises when B12 (and folate) can't convert it to methionine. High homocysteine = methylation"  
[X Link](https://x.com/Skinfolder/status/2018444448384909428)  2026-02-02T22:00Z [---] followers, [---] engagements


"Fiber makes some people feel worse because when gut bacteria ferments it gas is a byproduct. If you have overgrowth (SIBO) or the wrong bacteria too much fermentation. The result - bloating cramps brain fog loose stools. Cut fiber for [--] days bacteria starve temporary relief. Reintroduce fiber bacteria feast again symptoms come back. If this happens to you = likely bacterial overgrowth or dysbiosis. https://twitter.com/i/web/status/2018751377476927702 https://twitter.com/i/web/status/2018751377476927702"  
[X Link](https://x.com/Skinfolder/status/2018751377476927702)  2026-02-03T18:20Z [---] followers, [---] engagements


"This misses the circadian biology entirely. Your body isn't metabolically identical at 8am vs 8pm. Insulin sensitivity is highest in the morning and declines throughout the day - controlled by clock genes (BMAL1 CLOCK PER) in your pancreas and liver. Morning is when you're biochemically primed to handle glucose most efficiently. Studies comparing early time-restricted feeding (breakfast + lunch skip dinner) vs late TRF (skip breakfast eat dinner) consistently show better outcomes with early eating: improved insulin sensitivity lower glucose better fat loss. Same calories same fasting window"  
[X Link](https://x.com/Skinfolder/status/2018803808000680043)  2026-02-03T21:48Z [---] followers, [----] engagements


"@notyourpleaser @iloveveganpvssy And the studies supporting animal foods reduction to make the population weaker and dumber arent state planning I'm glad you're able to say go vegan based on well documented evidence that doesn't exist but whatever floats your boat"  
[X Link](https://x.com/Skinfolder/status/2018854695096467866)  2026-02-04T01:10Z [---] followers, [--] engagements


"This works best in specific contexts: - Heavy training losing 500-1500mg sodium/hour in sweat - Low-carb/keto insulin drops kidneys dump sodium (this is "keto flu") - Fasting same mechanism no insulin means sodium excretion A pinch is 200-400mg. If you're actually depleted you might need 1-2g daily (1/2 tsp) spread out. https://twitter.com/i/web/status/2019130111736340837 https://twitter.com/i/web/status/2019130111736340837"  
[X Link](https://x.com/Skinfolder/status/2019130111736340837)  2026-02-04T19:25Z [---] followers, [----] engagements


"True but if magnesium isn't working for your anxiety - check B1. B1 deficiency mimics magnesium deficiency perfectly because they're a "functional team" in the body. Magnesium blocks NMDA receptors (reduces excitatory signaling) and activates GABA (calming). It also breaks down cortisol and adrenaline. But B1-dependent enzymes need magnesium to convert glucose into ATP. Without adequate thiamine your cells can't make energy even with sufficient magnesium. The tell: you feel worse after eating carbsbrain fog anxiety spike fatigue. That's failed glucose metabolism"  
[X Link](https://x.com/Skinfolder/status/2018059682418758009)  2026-02-01T20:31Z [---] followers, [----] engagements


"There are few explanations sometimes its a mix of few unfortunately. Too much glutamate is pulled out making you actually low on glutamate which causes anhedonia. Some research also shows that NAC reduces dopamine release with fast MAOA it can be quite annoying as well. In people that dont eat enough molbydenum could also be slight sulfites toxicity from NAC so replenishing molbydenum solves it. Another issue is NAC's chelating impact it can pull heavy metals. I wouldnt recommend to take NAC as solution for high glutamate however it works for some but it never solves the core issue."  
[X Link](https://x.com/Skinfolder/status/2018433698886979784)  2026-02-02T21:17Z [---] followers, [--] engagements

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