[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @MTD_000 Mastering The Differential 🩺 Mastering The Differential 🩺 posts on X about what is, ct, transient, honey can the most. They currently have XXXXX followers and XXX posts still getting attention that total XXXXX engagements in the last XX hours. ### Engagements: XXXXX [#](/creator/twitter::1656372774351302686/interactions)  - X Week XXXXXX -XX% - X Month XXXXXXX +2,276% ### Mentions: XX [#](/creator/twitter::1656372774351302686/posts_active)  ### Followers: XXXXX [#](/creator/twitter::1656372774351302686/followers)  - X Week XXXXX +85% - X Month XXXXX +387% ### CreatorRank: XXXXXXX [#](/creator/twitter::1656372774351302686/influencer_rank)  ### Social Influence **Social category influence** [finance](/list/finance) [countries](/list/countries) [technology brands](/list/technology-brands) **Social topic influence** [what is](/topic/what-is), [ct](/topic/ct) #962, [transient](/topic/transient), [honey can](/topic/honey-can), [vt](/topic/vt), [derivatives](/topic/derivatives), [to the](/topic/to-the), [core](/topic/core), [$6753t](/topic/$6753t), [breakdown](/topic/breakdown) **Top accounts mentioned or mentioned by** [@drakhilx](/creator/undefined) [@moarsahitopti](/creator/undefined) [@simplifydrugs](/creator/undefined) [@jus_caws](/creator/undefined) ### Top Social Posts Top posts by engagements in the last XX hours "Persimmon Bezoar (Diospyrobezoar) A persimmon bezoar is a type of phytobezoar formed after eating large amounts of unripe persimmons. Unripe persimmons contain a tannin called shibuol which polymerizes in the acidic stomach forming a hard rock-like mass. 🔥 Who gets it Heavy persimmon eaters Poor gastric motility (diabetes prior gastric surgery) Low gastric acid Elderly patients 🧪 Clinical features Epigastric pain Early satiety Nausea/vomiting Gastric outlet obstruction in severe cases 📸 Diagnosis Endoscopy (best) CT: well-defined intragastric mass with mottled appearance 💊 Treatment" [X Link](https://x.com/MTD_000/status/1996563122077716856) 2025-12-04T12:51Z 3253 followers, XXX engagements "A 23-year-old man presents with episodic severe abdominal pain flushing and watery diarrhea. He also reports losing weight despite eating normally. On exam he has wheezing and the finding below. 24-hour urine test shows elevated 5-HIAA. Whats the most likely diagnosis A) VIPoma B) Pheochromocytoma C) Carcinoid syndrome D) Hyperthyroidism" [X Link](https://x.com/MTD_000/status/1997043293356765205) 2025-12-05T20:39Z 3206 followers, XXX engagements "A 34-year-old woman presents with recurrent episodes of chest pain that occur at rest often waking her from sleep. ECG during an episode shows transient ST-segment elevation and troponins are normal. Symptoms improve rapidly after sublingual nitroglycerin. Whats the most likely diagnosis A) Unstable angina B) STEMI C) Prinzmetal (vasospastic) angina D) Pericarditis" [X Link](https://x.com/MTD_000/status/1997044116107239836) 2025-12-05T20:43Z 3251 followers, XXX engagements "❌ False. Constrictive pericarditis is not a common cardiac manifestation of systemic lupus erythematosus (SLE). 🔹 What is common in SLE Acute pericarditis Recurrent pericarditis Myocarditis (less common) Libman-Sacks endocarditis 🔹 Why constrictive pericarditis is uncommon Because SLE-related pericardial inflammation is usually mild serositis that responds to treatment and rarely progresses to chronic fibrosis or calcification. So: SLE pericarditis is common but constrictive pericarditis is very rare" [X Link](https://x.com/MTD_000/status/1997254438101086483) 2025-12-06T10:38Z 3221 followers, XXX engagements "🍯 Never give honey to babies under X year old. Infant gut flora is not fully developed so Clostridium botulinum spores found in honey can germinate and produce botulinum toxin. This leads to infant botulism a serious condition causing constipation weak cry poor feeding hypotonia and potentially respiratory failure. Honey is safe for older children but strictly avoided in infants" [X Link](https://x.com/MTD_000/status/1997401289936756813) 2025-12-06T20:22Z 3225 followers, XX engagements "🧪 How does ethanol help in methanol poisoning Because ethanol competes for the same enzyme alcohol dehydrogenase (ADH). 💥 Key idea: Methanol itself is NOT the killer. Its toxic metabolites formic acid + formaldehyde cause: Blindness 👁 Severe metabolic acidosis CNS toxicity Ethanol has much higher affinity for ADH It blocks methanol from being metabolized buying time for the body to excrete unmetabolized methanol safely. 🎯 Result: Less formic acid less acidosis less retinal & CNS damage. Thats why ethanol (or fomepizole the preferred antidote) is used in methanol poisoning" [X Link](https://x.com/MTD_000/status/1998001114126389685) 2025-12-08T12:06Z 3252 followers, XXX engagements "Diagnosis: GorlinGoltz Syndrome (Nevoid Basal Cell Carcinoma Syndrome) 🔥 Key features shown in the image: Multiple basal cell carcinomas Odontogenic keratocysts of the jaw Bifid ribs Palmar/plantar pits Calcification of the falx cerebri Ocular hypertelorism Epidermal inclusion cysts 📌 Cause: Autosomal dominant mutation in PTCH1 (tumor suppressor gene) on chromosome X. 🎯 Classic triad: X Multiple BCCs X Jaw cysts (odontogenic keratocysts) X Skeletal anomalies (bifid ribs)Bottom line: This constellation = GorlinGoltz Syndrome" [X Link](https://x.com/MTD_000/status/1996959713397731676) 2025-12-05T15:07Z 3261 followers, XXX engagements "Why give Magnesium sulfate in Torsades de Pointes Because Mg stabilizes the cardiac electrical system and terminates the arrhythmia even when serum magnesium is normal. 🔬 Mechanism (high-yield): TdP is a form of polymorphic VT caused by prolonged QT (early after-depolarizations). Magnesium blocks calcium influx during repolarization ✔ Suppresses early after-depolarizations ✔ Prevents the triggering beats that start TdP ✔ Shortens QT slightlyIt works by stabilizing myocardial cells not by raising serum magnesium levels. 🫀 Why its preferred: Rapid onset Effective even if magnesium is normal" [X Link](https://x.com/MTD_000/status/1997621963896795307) 2025-12-07T10:59Z 3264 followers, 3305 engagements "🧠🧊 Anti-Parkinsonian drug that causes peripheral vasospasm: ➡ A) Bromocriptine 💡 Why Bromocriptine is an ergot-derived dopamine agonist and ergot derivatives cause vasoconstriction which can lead to: Peripheral vasospasm Raynaud-like symptoms Digital ischemia (rare) ❌ Why the others are wrong: Levodopa Can cause dyskinesia hypotension hallucinations; not vasospasm. Ropinirole Non-ergot dopamine agonist no vasospasm risk. Entacapone COMT inhibitor; causes diarrhea orange urine; no vasospasm" [X Link](https://x.com/MTD_000/status/1998389154812506312) 2025-12-09T13:47Z 3262 followers, XXX engagements "Mechanism of Action of Rifamycins (Rifampin & Rifabutin) Rifamycins inhibit bacterial RNA synthesis by: 🧬 Binding to the -subunit of DNA-dependent RNA polymerase Blocks mRNA transcription Stops protein synthesis Bactericidal This is why theyre powerful against Mycobacterium tuberculosis some Gram+ Gram and N. meningitidis prophylaxis. 🔥 One-liner: Rifampin inhibits DNA-dependent RNA polymerase no RNA no proteins bacterial death" [X Link](https://x.com/MTD_000/status/1997699739962290305) 2025-12-07T16:08Z 3451 followers, XX engagements "❄ Osborn wave (J wave) 💡 What is it A positive deflection at the J-point (junction of QRS and ST) seen as a little hump after the QRS. 🥶 Classic association: Severe hypothermia usually when core temp 32C. 📌 Other causes (dont forget these): Hypercalcemia Early repolarization Brugada pattern mimic Brain injury (SAH) Sepsis Cardiac arrest resuscitation states 📈 Why it happens (simple): Temperature- or electrolyte-induced differences in early ventricular repolarization creates a voltage gradient visible J wave. 🩹 Clinical pearl: In hypothermia the Osborn wave size often correlates with" [X Link](https://x.com/MTD_000/status/1998066876526563677) 2025-12-08T16:27Z 3453 followers, 15.6K engagements "🖐 Finkelstein Test Quick High-Yield Breakdown 👉 What it tests for: De Quervains tenosynovitis (inflammation of the APL + EPB tendons in the 1st dorsal compartment) 👉 How to perform it: Patient makes a fist with the thumb inside Examiner ulnar-deviates the wrist Sharp pain over the radial styloid = positive 👉 Why it hurts: Ulnar deviation stretches the inflamed APL/EPB tendons produces the classic lateral wrist pain. 👉 Clinical clue: New mothers repetitive lifting gamers typists gym users" [X Link](https://x.com/MTD_000/status/1999066760037675123) 2025-12-11T10:40Z 3455 followers, XXX engagements "This is Dermatitis Herpetiformis the classic skin manifestation of Celiac disease. 🧠 Why this fits: Intolerance to protein specifically gluten Recurrent diarrhea weight loss abdominal discomfort Intensely itchy grouped vesicles and excoriations on extensor surfaces (elbows knees buttocks) Caused by IgA deposition in dermal papillae. 🔥 Diagnosis: ✅ Dermatitis Herpetiformis secondary to Celiac disease" [X Link](https://x.com/MTD_000/status/1999067833670451481) 2025-12-11T10:44Z 3456 followers, XXX engagements "@simplify_drugs Oseltamivir (Tamiflu) is active against: ✅ Both Influenza A and Influenza B 🧠 Why It inhibits neuraminidase an enzyme required for viral release and this enzyme is present in both influenza A and B viruses" [X Link](https://x.com/MTD_000/status/1999070784573321311) 2025-12-11T10:56Z 3455 followers, XXX engagements "The drug that is safe for humans and dogs but highly toxic to cats is: ✅ Paracetamol (Acetaminophen) 😺 Why is it deadly for cats Cats lack the enzyme glucuronyl transferase which is required to metabolize paracetamol safely. So instead the drug is converted into a toxic metabolite (NAPQI) that causes: ☠ Severe oxidative damage Methemoglobinemia brown/blue gums respiratory distress Heinz body hemolytic anemia Liver failure Even a single tablet can be fatal to a cat. 🐕 Why can dogs tolerate it Dogs do have the needed enzymes (although overdose is still dangerous). Humans also metabolize it" [X Link](https://x.com/MTD_000/status/1999070998482571699) 2025-12-11T10:57Z 3453 followers, XXX engagements "The triad of findings in your images + the symptoms (dysarthria + ataxic gait) point to one classic neuromuscularskeletal disease: ✅ Friedreich Ataxia 🧠 How the pictures fit: X Scoliosis (first image) Very common in Friedreich ataxia due to progressive neuromuscular weakness. X Pes cavus / high-arched foot (second image) A hallmark of hereditary neuropathies especially Friedreich ataxia. X Hypertrophic cardiomyopathy (third image) Friedreich ataxia often causes hypertrophic cardiomyopathy the leading cause of death in these patients. 🧬 Symptoms match too: Dysarthria ✔ Ataxic gait ✔ Loss of" [X Link](https://x.com/MTD_000/status/1999071796851581033) 2025-12-11T11:00Z 3452 followers, XXX engagements "Correct answer: B. DRESS syndrome Why: Allopurinol is one of the most classic triggers of DRESS. T he triad to remember is: Rash Eosinophilia Systemic involvement (liver kidney lung)Why others are wrong: A. SJS mucosal erosions + targetoid lesions; eosinophilia is not typical. C. TEN severe epidermal necrolysis with XX% BSA detachment; no eosinophilia. D. Urticaria itchy wheals; no eosinophilia no systemic inflammation.➡ Rash + eosinophilia + allopurinol = DRESS" [X Link](https://x.com/MTD_000/status/1995573966501491111) 2025-12-01T19:21Z 3407 followers, 3622 engagements "✅ Endemic Burkitt Lymphoma (African type) Key Points 🦠 Cause Almost always associated with EBV infection (95% of cases). 🌍 Geography Occurs mainly in malaria-endemic regions of Africa and Papua New Guinea. 👶 Demographics Mostly children. 🦷 Most common presentation Jaw or facial bone mass Classically large rapidly growing often involving the mandible or maxilla. 🔬 Molecular hallmark t(8;14) translocation c-MYC overexpression. 🧪 Histology Starry sky appearance (macrophages with clear cytoplasm among sheets of tumor cells). Summary 👉 Endemic Burkitt lymphoma = EBV-driven African type" [X Link](https://x.com/MTD_000/status/1995889666768224374) 2025-12-02T16:15Z 3357 followers, XXX engagements "Diagnosis: Hypertriglyceridemia-induced acute pancreatitisThe blood sample is milky/creamy this is lipemic serum caused by severely elevated triglycerides (often 1000 mg/dL).Combined with: Severe abdominal pain Elevated amylase/lipase➡ This points strongly to acute pancreatitis due to hypertriglyceridemia.Why the serum looks like this: Extremely high triglycerides make the plasma appear creamy opaque and milky instead of clear.Classic triad: Abdominal pain Elevated pancreatic enzymes Milky blood sampleThis is one of the top X causes of pancreatitis (gallstones alcohol hypertriglyceridemia)" [X Link](https://x.com/MTD_000/status/1995577362851729914) 2025-12-01T19:34Z 3455 followers, 552.4K engagements "orrect answer: C. Atoll sign 🧠 Why Central ground-glass opacity surrounded by a ring of denser consolidation = Atoll sign (also called reverse halo sign). Seen in: Organizing pneumonia (classic) Pulmonary infarction Fungal infections (e.g. mucormycosis) Granulomatosis with polyangiitis ❌ Why others are wrong: A) Halo sign Dense nodule with surrounding ground-glass (opposite of atoll). B) Tree-in-bud Centrilobular nodules + branching TB/bronchiolitis. D) Air crescent sign Crescent of air around fungal ball (aspergilloma or recovering angioinvasive aspergillosis)" [X Link](https://x.com/MTD_000/status/1998080895278796962) 2025-12-08T17:23Z 3440 followers, XXX engagements "The image shows a newborn with an open spinal defect and herniation of meninges + neural tissue. This is classic for: ✅ B. Spina bifida (specifically Myelomeningocele) 🧠 Why Visible sac on the lower back Neural elements protruding Failure of posterior vertebral arches to close Most severe form of open neural tube defect ❌ Why the others are wrong: A. Anencephaly absence of major portions of brain/skull not a spinal lesion C. ArnoldChiari malformation hindbrain herniation often associated with spina bifida but not what's shown D. Meningitis no external defect like this 🎯 Final Answer: B." [X Link](https://x.com/MTD_000/status/1999123580785762491) 2025-12-11T14:26Z 3456 followers, XXX engagements "ChatGPT said: 🔥 The one symptom that should instantly trigger a RED-ALERT diagnosis 🟥 Worst headache of my life. This phrase = subarachnoid hemorrhage until proven otherwise. Why its dangerous: Sudden explosive onset (thunderclap) Often due to ruptured berry aneurysm Can rapidly progress to coma death CT head + LP (if CT negative) = mandatory Early neurosurgical involvement is critical Other red-alert equivalents patients may say: A tearing pain to my back aortic dissection I cant feel my legs / I cant pee cauda equina Crushing chest pressure ACS until proven otherwise But the #1 classic" [X Link](https://x.com/MTD_000/status/1999154692362735647) 2025-12-11T16:29Z 3452 followers, XXX engagements "🟥 Diagnosis: Renal Artery Stenosis (likely bilateral) Pickering Syndrome This constellation is textbook for renovascular hypertension causing recurrent flash pulmonary edema. 🔥 Key clues: 🌙 Sudden nocturnal dyspnea recurrent flash pulmonary edema ⚡ Severely elevated BP (220/120) ⛓ Worsening peripheral edema 🌊 Pulmonary edema episodes out of proportion to LV function 🚫 Acute fall in urine output after ACEi/ARB 📈 Creatinine spikes after ACEi/ARB hallmark of bilateral RAS Why this happens: ACEi/ARB dilate the efferent arteriole drop GFR creatinine rises oliguria This only happens" [X Link](https://x.com/MTD_000/status/1999157842717122768) 2025-12-11T16:42Z 3455 followers, XXX engagements "🩺 HbA1c reflects average blood glucose over the past X months (812 weeks). 📌 Why Red blood cells live XXX days and glucose binds irreversibly to hemoglobin. The A1c level therefore mirrors the mean glycemic exposure over the lifespan of circulating RBCs. Quick breakdown: Last XX days weighted most heavily Last XX days full integrated average 🔥 Pearl: Think of HbA1c as the 3-month glucose report card" [X Link](https://x.com/MTD_000/status/1995808281860665732) 2025-12-02T10:52Z 3446 followers, 1847 engagements "Herpes labialis = the classic cold sore caused by HSV-1 (Herpes Simplex Virus type 1). Heres a clean organized medical explanation: --- Cause Almost always HSV-1 Virus stays latent in the trigeminal ganglion (CN V) and reactivates with: Stress Fever / illness Sunlight Menstruation Immunosuppression --- Clinical Features Prodrome: tingling burning pain Lesions: grouped vesicles on an erythematous base usually on the lip border Vesicles rupture crust heal in XXX days Often recurrent but severity decreases over time No scarring --- Diagnosis Usually clinical. If needed: PCR from swab Tzanck" [X Link](https://x.com/MTD_000/status/1997078380445888579) 2025-12-05T22:59Z 3455 followers, 34.1K engagements "🧍♂🔍 Adams Forward Bending Test A simple high-yield clinical test used to screen for scoliosis. 💡 What it is: The patient bends forward at the waist (like touching toes) while the examiner looks at the back from behind. 👀 Positive test = Rib hump One side of the ribs appears higher than the other Indicates structural scoliosis due to vertebral rotation 🧠 Why it matters: Structural scoliosis rib hump present Postural scoliosis rib hump absent (spine straightens when bending) 🩺 When used: School screening Assessing suspected scoliosis in clinic" [X Link](https://x.com/MTD_000/status/1998383538056388829) 2025-12-09T13:25Z 3447 followers, XXX engagements "🧠⚡ First test for worst headache of my life (suspected subarachnoid hemorrhage) ✅ Non-contrast CT head Why Fast Highly sensitive within the first X hours Detects acute blood in the subarachnoid space Immediately rules in SAH if positive If CT is negative but suspicion is still high 🔁 Lumbar puncture to look for xanthochromia. 🔥 Takeaway: Worst headache of life = Non-contrast CT head FIRST" [X Link](https://x.com/MTD_000/status/1999170231403495659) 2025-12-11T17:31Z 3453 followers, XXX engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@MTD_000 Mastering The Differential 🩺
Mastering The Differential 🩺 posts on X about what is, ct, transient, honey can the most. They currently have XXXXX followers and XXX posts still getting attention that total XXXXX engagements in the last XX hours.
Engagements: XXXXX #
- X Week XXXXXX -XX%
- X Month XXXXXXX +2,276%
Mentions: XX #
Followers: XXXXX #
- X Week XXXXX +85%
- X Month XXXXX +387%
CreatorRank: XXXXXXX #
Social Influence
Social category influence finance countries technology brands
Social topic influence what is, ct #962, transient, honey can, vt, derivatives, to the, core, $6753t, breakdown
Top accounts mentioned or mentioned by @drakhilx @moarsahitopti @simplifydrugs @jus_caws
Top Social Posts
Top posts by engagements in the last XX hours
"Persimmon Bezoar (Diospyrobezoar) A persimmon bezoar is a type of phytobezoar formed after eating large amounts of unripe persimmons. Unripe persimmons contain a tannin called shibuol which polymerizes in the acidic stomach forming a hard rock-like mass. 🔥 Who gets it Heavy persimmon eaters Poor gastric motility (diabetes prior gastric surgery) Low gastric acid Elderly patients 🧪 Clinical features Epigastric pain Early satiety Nausea/vomiting Gastric outlet obstruction in severe cases 📸 Diagnosis Endoscopy (best) CT: well-defined intragastric mass with mottled appearance 💊 Treatment"
X Link 2025-12-04T12:51Z 3253 followers, XXX engagements
"A 23-year-old man presents with episodic severe abdominal pain flushing and watery diarrhea. He also reports losing weight despite eating normally. On exam he has wheezing and the finding below. 24-hour urine test shows elevated 5-HIAA. Whats the most likely diagnosis A) VIPoma B) Pheochromocytoma C) Carcinoid syndrome D) Hyperthyroidism"
X Link 2025-12-05T20:39Z 3206 followers, XXX engagements
"A 34-year-old woman presents with recurrent episodes of chest pain that occur at rest often waking her from sleep. ECG during an episode shows transient ST-segment elevation and troponins are normal. Symptoms improve rapidly after sublingual nitroglycerin. Whats the most likely diagnosis A) Unstable angina B) STEMI C) Prinzmetal (vasospastic) angina D) Pericarditis"
X Link 2025-12-05T20:43Z 3251 followers, XXX engagements
"❌ False. Constrictive pericarditis is not a common cardiac manifestation of systemic lupus erythematosus (SLE). 🔹 What is common in SLE Acute pericarditis Recurrent pericarditis Myocarditis (less common) Libman-Sacks endocarditis 🔹 Why constrictive pericarditis is uncommon Because SLE-related pericardial inflammation is usually mild serositis that responds to treatment and rarely progresses to chronic fibrosis or calcification. So: SLE pericarditis is common but constrictive pericarditis is very rare"
X Link 2025-12-06T10:38Z 3221 followers, XXX engagements
"🍯 Never give honey to babies under X year old. Infant gut flora is not fully developed so Clostridium botulinum spores found in honey can germinate and produce botulinum toxin. This leads to infant botulism a serious condition causing constipation weak cry poor feeding hypotonia and potentially respiratory failure. Honey is safe for older children but strictly avoided in infants"
X Link 2025-12-06T20:22Z 3225 followers, XX engagements
"🧪 How does ethanol help in methanol poisoning Because ethanol competes for the same enzyme alcohol dehydrogenase (ADH). 💥 Key idea: Methanol itself is NOT the killer. Its toxic metabolites formic acid + formaldehyde cause: Blindness 👁 Severe metabolic acidosis CNS toxicity Ethanol has much higher affinity for ADH It blocks methanol from being metabolized buying time for the body to excrete unmetabolized methanol safely. 🎯 Result: Less formic acid less acidosis less retinal & CNS damage. Thats why ethanol (or fomepizole the preferred antidote) is used in methanol poisoning"
X Link 2025-12-08T12:06Z 3252 followers, XXX engagements
"Diagnosis: GorlinGoltz Syndrome (Nevoid Basal Cell Carcinoma Syndrome) 🔥 Key features shown in the image: Multiple basal cell carcinomas Odontogenic keratocysts of the jaw Bifid ribs Palmar/plantar pits Calcification of the falx cerebri Ocular hypertelorism Epidermal inclusion cysts 📌 Cause: Autosomal dominant mutation in PTCH1 (tumor suppressor gene) on chromosome X. 🎯 Classic triad: X Multiple BCCs X Jaw cysts (odontogenic keratocysts) X Skeletal anomalies (bifid ribs)Bottom line: This constellation = GorlinGoltz Syndrome"
X Link 2025-12-05T15:07Z 3261 followers, XXX engagements
"Why give Magnesium sulfate in Torsades de Pointes Because Mg stabilizes the cardiac electrical system and terminates the arrhythmia even when serum magnesium is normal. 🔬 Mechanism (high-yield): TdP is a form of polymorphic VT caused by prolonged QT (early after-depolarizations). Magnesium blocks calcium influx during repolarization ✔ Suppresses early after-depolarizations ✔ Prevents the triggering beats that start TdP ✔ Shortens QT slightlyIt works by stabilizing myocardial cells not by raising serum magnesium levels. 🫀 Why its preferred: Rapid onset Effective even if magnesium is normal"
X Link 2025-12-07T10:59Z 3264 followers, 3305 engagements
"🧠🧊 Anti-Parkinsonian drug that causes peripheral vasospasm: ➡ A) Bromocriptine 💡 Why Bromocriptine is an ergot-derived dopamine agonist and ergot derivatives cause vasoconstriction which can lead to: Peripheral vasospasm Raynaud-like symptoms Digital ischemia (rare) ❌ Why the others are wrong: Levodopa Can cause dyskinesia hypotension hallucinations; not vasospasm. Ropinirole Non-ergot dopamine agonist no vasospasm risk. Entacapone COMT inhibitor; causes diarrhea orange urine; no vasospasm"
X Link 2025-12-09T13:47Z 3262 followers, XXX engagements
"Mechanism of Action of Rifamycins (Rifampin & Rifabutin) Rifamycins inhibit bacterial RNA synthesis by: 🧬 Binding to the -subunit of DNA-dependent RNA polymerase Blocks mRNA transcription Stops protein synthesis Bactericidal This is why theyre powerful against Mycobacterium tuberculosis some Gram+ Gram and N. meningitidis prophylaxis. 🔥 One-liner: Rifampin inhibits DNA-dependent RNA polymerase no RNA no proteins bacterial death"
X Link 2025-12-07T16:08Z 3451 followers, XX engagements
"❄ Osborn wave (J wave) 💡 What is it A positive deflection at the J-point (junction of QRS and ST) seen as a little hump after the QRS. 🥶 Classic association: Severe hypothermia usually when core temp 32C. 📌 Other causes (dont forget these): Hypercalcemia Early repolarization Brugada pattern mimic Brain injury (SAH) Sepsis Cardiac arrest resuscitation states 📈 Why it happens (simple): Temperature- or electrolyte-induced differences in early ventricular repolarization creates a voltage gradient visible J wave. 🩹 Clinical pearl: In hypothermia the Osborn wave size often correlates with"
X Link 2025-12-08T16:27Z 3453 followers, 15.6K engagements
"🖐 Finkelstein Test Quick High-Yield Breakdown 👉 What it tests for: De Quervains tenosynovitis (inflammation of the APL + EPB tendons in the 1st dorsal compartment) 👉 How to perform it: Patient makes a fist with the thumb inside Examiner ulnar-deviates the wrist Sharp pain over the radial styloid = positive 👉 Why it hurts: Ulnar deviation stretches the inflamed APL/EPB tendons produces the classic lateral wrist pain. 👉 Clinical clue: New mothers repetitive lifting gamers typists gym users"
X Link 2025-12-11T10:40Z 3455 followers, XXX engagements
"This is Dermatitis Herpetiformis the classic skin manifestation of Celiac disease. 🧠 Why this fits: Intolerance to protein specifically gluten Recurrent diarrhea weight loss abdominal discomfort Intensely itchy grouped vesicles and excoriations on extensor surfaces (elbows knees buttocks) Caused by IgA deposition in dermal papillae. 🔥 Diagnosis: ✅ Dermatitis Herpetiformis secondary to Celiac disease"
X Link 2025-12-11T10:44Z 3456 followers, XXX engagements
"@simplify_drugs Oseltamivir (Tamiflu) is active against: ✅ Both Influenza A and Influenza B 🧠 Why It inhibits neuraminidase an enzyme required for viral release and this enzyme is present in both influenza A and B viruses"
X Link 2025-12-11T10:56Z 3455 followers, XXX engagements
"The drug that is safe for humans and dogs but highly toxic to cats is: ✅ Paracetamol (Acetaminophen) 😺 Why is it deadly for cats Cats lack the enzyme glucuronyl transferase which is required to metabolize paracetamol safely. So instead the drug is converted into a toxic metabolite (NAPQI) that causes: ☠ Severe oxidative damage Methemoglobinemia brown/blue gums respiratory distress Heinz body hemolytic anemia Liver failure Even a single tablet can be fatal to a cat. 🐕 Why can dogs tolerate it Dogs do have the needed enzymes (although overdose is still dangerous). Humans also metabolize it"
X Link 2025-12-11T10:57Z 3453 followers, XXX engagements
"The triad of findings in your images + the symptoms (dysarthria + ataxic gait) point to one classic neuromuscularskeletal disease: ✅ Friedreich Ataxia 🧠 How the pictures fit: X Scoliosis (first image) Very common in Friedreich ataxia due to progressive neuromuscular weakness. X Pes cavus / high-arched foot (second image) A hallmark of hereditary neuropathies especially Friedreich ataxia. X Hypertrophic cardiomyopathy (third image) Friedreich ataxia often causes hypertrophic cardiomyopathy the leading cause of death in these patients. 🧬 Symptoms match too: Dysarthria ✔ Ataxic gait ✔ Loss of"
X Link 2025-12-11T11:00Z 3452 followers, XXX engagements
"Correct answer: B. DRESS syndrome Why: Allopurinol is one of the most classic triggers of DRESS. T he triad to remember is: Rash Eosinophilia Systemic involvement (liver kidney lung)Why others are wrong: A. SJS mucosal erosions + targetoid lesions; eosinophilia is not typical. C. TEN severe epidermal necrolysis with XX% BSA detachment; no eosinophilia. D. Urticaria itchy wheals; no eosinophilia no systemic inflammation.➡ Rash + eosinophilia + allopurinol = DRESS"
X Link 2025-12-01T19:21Z 3407 followers, 3622 engagements
"✅ Endemic Burkitt Lymphoma (African type) Key Points 🦠 Cause Almost always associated with EBV infection (95% of cases). 🌍 Geography Occurs mainly in malaria-endemic regions of Africa and Papua New Guinea. 👶 Demographics Mostly children. 🦷 Most common presentation Jaw or facial bone mass Classically large rapidly growing often involving the mandible or maxilla. 🔬 Molecular hallmark t(8;14) translocation c-MYC overexpression. 🧪 Histology Starry sky appearance (macrophages with clear cytoplasm among sheets of tumor cells). Summary 👉 Endemic Burkitt lymphoma = EBV-driven African type"
X Link 2025-12-02T16:15Z 3357 followers, XXX engagements
"Diagnosis: Hypertriglyceridemia-induced acute pancreatitisThe blood sample is milky/creamy this is lipemic serum caused by severely elevated triglycerides (often 1000 mg/dL).Combined with: Severe abdominal pain Elevated amylase/lipase➡ This points strongly to acute pancreatitis due to hypertriglyceridemia.Why the serum looks like this: Extremely high triglycerides make the plasma appear creamy opaque and milky instead of clear.Classic triad: Abdominal pain Elevated pancreatic enzymes Milky blood sampleThis is one of the top X causes of pancreatitis (gallstones alcohol hypertriglyceridemia)"
X Link 2025-12-01T19:34Z 3455 followers, 552.4K engagements
"orrect answer: C. Atoll sign 🧠 Why Central ground-glass opacity surrounded by a ring of denser consolidation = Atoll sign (also called reverse halo sign). Seen in: Organizing pneumonia (classic) Pulmonary infarction Fungal infections (e.g. mucormycosis) Granulomatosis with polyangiitis ❌ Why others are wrong: A) Halo sign Dense nodule with surrounding ground-glass (opposite of atoll). B) Tree-in-bud Centrilobular nodules + branching TB/bronchiolitis. D) Air crescent sign Crescent of air around fungal ball (aspergilloma or recovering angioinvasive aspergillosis)"
X Link 2025-12-08T17:23Z 3440 followers, XXX engagements
"The image shows a newborn with an open spinal defect and herniation of meninges + neural tissue. This is classic for: ✅ B. Spina bifida (specifically Myelomeningocele) 🧠 Why Visible sac on the lower back Neural elements protruding Failure of posterior vertebral arches to close Most severe form of open neural tube defect ❌ Why the others are wrong: A. Anencephaly absence of major portions of brain/skull not a spinal lesion C. ArnoldChiari malformation hindbrain herniation often associated with spina bifida but not what's shown D. Meningitis no external defect like this 🎯 Final Answer: B."
X Link 2025-12-11T14:26Z 3456 followers, XXX engagements
"ChatGPT said: 🔥 The one symptom that should instantly trigger a RED-ALERT diagnosis 🟥 Worst headache of my life. This phrase = subarachnoid hemorrhage until proven otherwise. Why its dangerous: Sudden explosive onset (thunderclap) Often due to ruptured berry aneurysm Can rapidly progress to coma death CT head + LP (if CT negative) = mandatory Early neurosurgical involvement is critical Other red-alert equivalents patients may say: A tearing pain to my back aortic dissection I cant feel my legs / I cant pee cauda equina Crushing chest pressure ACS until proven otherwise But the #1 classic"
X Link 2025-12-11T16:29Z 3452 followers, XXX engagements
"🟥 Diagnosis: Renal Artery Stenosis (likely bilateral) Pickering Syndrome This constellation is textbook for renovascular hypertension causing recurrent flash pulmonary edema. 🔥 Key clues: 🌙 Sudden nocturnal dyspnea recurrent flash pulmonary edema ⚡ Severely elevated BP (220/120) ⛓ Worsening peripheral edema 🌊 Pulmonary edema episodes out of proportion to LV function 🚫 Acute fall in urine output after ACEi/ARB 📈 Creatinine spikes after ACEi/ARB hallmark of bilateral RAS Why this happens: ACEi/ARB dilate the efferent arteriole drop GFR creatinine rises oliguria This only happens"
X Link 2025-12-11T16:42Z 3455 followers, XXX engagements
"🩺 HbA1c reflects average blood glucose over the past X months (812 weeks). 📌 Why Red blood cells live XXX days and glucose binds irreversibly to hemoglobin. The A1c level therefore mirrors the mean glycemic exposure over the lifespan of circulating RBCs. Quick breakdown: Last XX days weighted most heavily Last XX days full integrated average 🔥 Pearl: Think of HbA1c as the 3-month glucose report card"
X Link 2025-12-02T10:52Z 3446 followers, 1847 engagements
"Herpes labialis = the classic cold sore caused by HSV-1 (Herpes Simplex Virus type 1). Heres a clean organized medical explanation: --- Cause Almost always HSV-1 Virus stays latent in the trigeminal ganglion (CN V) and reactivates with: Stress Fever / illness Sunlight Menstruation Immunosuppression --- Clinical Features Prodrome: tingling burning pain Lesions: grouped vesicles on an erythematous base usually on the lip border Vesicles rupture crust heal in XXX days Often recurrent but severity decreases over time No scarring --- Diagnosis Usually clinical. If needed: PCR from swab Tzanck"
X Link 2025-12-05T22:59Z 3455 followers, 34.1K engagements
"🧍♂🔍 Adams Forward Bending Test A simple high-yield clinical test used to screen for scoliosis. 💡 What it is: The patient bends forward at the waist (like touching toes) while the examiner looks at the back from behind. 👀 Positive test = Rib hump One side of the ribs appears higher than the other Indicates structural scoliosis due to vertebral rotation 🧠 Why it matters: Structural scoliosis rib hump present Postural scoliosis rib hump absent (spine straightens when bending) 🩺 When used: School screening Assessing suspected scoliosis in clinic"
X Link 2025-12-09T13:25Z 3447 followers, XXX engagements
"🧠⚡ First test for worst headache of my life (suspected subarachnoid hemorrhage) ✅ Non-contrast CT head Why Fast Highly sensitive within the first X hours Detects acute blood in the subarachnoid space Immediately rules in SAH if positive If CT is negative but suspicion is still high 🔁 Lumbar puncture to look for xanthochromia. 🔥 Takeaway: Worst headache of life = Non-contrast CT head FIRST"
X Link 2025-12-11T17:31Z 3453 followers, XXX engagements