[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @JacobPlieth Jacob Plieth Jacob Plieth posts on X about $azn, $gild, $mrna, $dsnky the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXXX engagements in the last XX hours. ### Engagements: XXXXXX [#](/creator/twitter::873399943/interactions)  - X Week XXXXXX +1.90% - X Month XXXXXXX +21% - X Months XXXXXXXXX +14% - X Year XXXXXXXXX -XX% ### Mentions: XX [#](/creator/twitter::873399943/posts_active)  - X Week XX no change - X Month XX -X% - X Months XXX -XX% - X Year XXX +5.50% ### Followers: XXXXXX [#](/creator/twitter::873399943/followers)  - X Week XXXXXX +0.19% - X Month XXXXXX +1.10% - X Months XXXXXX +6.50% - X Year XXXXXX +12% ### CreatorRank: XXXXXXX [#](/creator/twitter::873399943/influencer_rank)  ### Social Influence [#](/creator/twitter::873399943/influence) --- **Social category influence** [stocks](/list/stocks) #5305 [currencies](/list/currencies) #774 [finance](/list/finance) XXXX% [cryptocurrencies](/list/cryptocurrencies) XXXX% **Social topic influence** [$azn](/topic/$azn) #3, [$gild](/topic/$gild) #1, [$mrna](/topic/$mrna) #9, [$dsnky](/topic/$dsnky) #2, [$lly](/topic/$lly) #5, [$rhhby](/topic/$rhhby) #1, [$legn](/topic/$legn) 1.06%, [$iobt](/topic/$iobt) #1, [$bmy](/topic/$bmy) #18, [$abbv](/topic/$abbv) #3 **Top accounts mentioned or mentioned by** [@apexonco](/creator/undefined) [@applehelix](/creator/undefined) [@bymadeleinea](/creator/undefined) [@bertrandbio](/creator/undefined) [@drpaulydesantis](/creator/undefined) [@notgenentech](/creator/undefined) [@maverickny](/creator/undefined) [@persimmonti](/creator/undefined) [@evaluatevantage](/creator/undefined) [@notthatkindofdr](/creator/undefined) [@biotechobserver](/creator/undefined) [@tman1138pm](/creator/undefined) [@avidresearch](/creator/undefined) [@phoenicianstrat](/creator/undefined) [@jeromeleonard5](/creator/undefined) [@jq1234t](/creator/undefined) [@garbageman1985](/creator/undefined) [@evaluatepharma](/creator/undefined) [@raffcolo](/creator/undefined) [@adamfeuerstein](/creator/undefined) **Top assets mentioned** [AstraZeneca PLC (AZN)](/topic/$azn) [Gilead Sciences, Inc. (GILD)](/topic/$gild) [Moderna Inc (MRNA)](/topic/$mrna) [Eli Lilly and Company (LLY)](/topic/$lly) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [AbbVie Inc (ABBV)](/topic/$abbv) [Novartis AG (NVS)](/topic/$nvs) [Amgen, Inc. (AMGN)](/topic/$amgn) [Synthetify (SNY)](/topic/$sny) [One Cash (ONC)](/topic/$onc) [Summit Therapeutics Inc. Common Stock (SMMT)](/topic/$smmt) [IDEAYA Biosciences, Inc. Common Stock (IDYA)](/topic/$idya) [Arvinas, Inc (ARVN)](/topic/$arvn) [Revolution Medicines, Inc. Common Stock (RVMD)](/topic/$rvmd) [Merus N.V. Common Shares (MRUS)](/topic/$mrus) [Incyte Corporation (INCY)](/topic/$incy) [Pfizer, Inc. (PFE)](/topic/$pfe) [Seagen Inc (SGEN)](/topic/$sgen) [Merck & Co., Inc. (MRK)](/topic/$mrk) [Nuvalent, Inc. Class A Common Stock (NUVL)](/topic/$nuvl) [Hundred Million (100M)](/topic/$100m) [GSK plc (GSK)](/topic/$gsk) ### Top Social Posts [#](/creator/twitter::873399943/posts) --- Top posts by engagements in the last XX hours "Wow so $AMGN slipped out that bemarituzumab's positive final OS analysis slipped into negative territory at longer follow-up. $ZLAB off X% yesterday -X% premarket today" [X Link](https://x.com/JacobPlieth/status/1963525096221364576) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-04T08:50Z 30.9K followers, 8709 engagements "$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24" [X Link](https://x.com/JacobPlieth/status/1866630560355061773) [@JacobPlieth](/creator/x/JacobPlieth) 2024-12-10T23:46Z 30.9K followers, 7600 engagements "#ESMO25 late-breaker LBA53 but now $IOBT says it can't file on IOB-013 study" [X Link](https://x.com/JacobPlieth/status/1972619740578521276) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-29T11:09Z 30.9K followers, 15.6K engagements "Now $BMY buys Orbital for. $1.5bn Focus seems to be autoimmune but pipeline also includes some oncology work $AZN $ABBV $GILD $SNY $ALPMF" [X Link](https://x.com/JacobPlieth/status/1976608534839357772) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-10T11:19Z 30.9K followers, 14.2K engagements "Is this a world record Seven days from data toplining to appearance in an #ESMO25 late-breaker $AZN" [X Link](https://x.com/JacobPlieth/status/1977658793690591360) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T08:52Z 30.9K followers, 3600 engagements "So the ILD grading shenanigans continue. Here's another grade X event adjudicated as grade X ILD $DSNKY $AZN #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979850770834141407) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T10:03Z 30.9K followers, 2034 engagements "New phase X Parp1 inhibitor from Synnovation $MKGAF $GILD $AZN" [X Link](https://x.com/JacobPlieth/status/1752324510047498715) [@JacobPlieth](/creator/x/JacobPlieth) 2024-01-30T13:34Z 30.9K followers, 7612 engagements "First patient now dosed in this study of TUB-040 Tubulis says. Relevant for $ZYME $ADCT $MRSN & MediLink" [X Link](https://x.com/JacobPlieth/status/1803793531779059837) [@JacobPlieth](/creator/x/JacobPlieth) 2024-06-20T14:14Z 30.9K followers, 4326 engagements "Catching up on some #ASCO25 sessions I came across this on dual-payload ADCs from Patricia LoRusso's clinical science symposium" [X Link](https://x.com/JacobPlieth/status/1930975237924893057) [@JacobPlieth](/creator/x/JacobPlieth) 2025-06-06T13:09Z 30.9K followers, 6665 engagements "$AMGN Fortitude-101 study of bemarituzumab (ex $FPRX) + chemo is stat sig "& clinically meaningful" for OS vs chemo alone. FGFR2boverexpression (10% @ IHC 2+/3+) was enrolment criterion I believe so this is a hit on ITT. $TYRA" [X Link](https://x.com/JacobPlieth/status/1939672763452539098) [@JacobPlieth](/creator/x/JacobPlieth) 2025-06-30T13:09Z 30.9K followers, 2801 engagements "You already have a small-molecule inhibitor so do you also need a degrader $ONC $BGNE thinks yes for BTK CDK2 & Kras. Via @ApexOnco - $ARVN $GILD $RVMD" [X Link](https://x.com/JacobPlieth/status/1939696857925533733) [@JacobPlieth](/creator/x/JacobPlieth) 2025-06-30T14:45Z 30.9K followers, 4695 engagements "More doubts for $SMMT as the Harmoni guessing game continues at #WCLC25. Via @ApexOnco - $BNTX $TIL $BMY" [X Link](https://x.com/JacobPlieth/status/1964771632154812790) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-07T19:23Z 30.9K followers, 11.4K engagements "First $AFMD now $IPHA. what say $ONC & any others still involved in NK-cell engagers" [X Link](https://x.com/JacobPlieth/status/1968302921881370818) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-17T13:16Z 30.9K followers, 5042 engagements "New players in dual-payload ADCs: Lonza Synaffix & Qurient Therapeutics. CDK7 inhibitor" [X Link](https://x.com/JacobPlieth/status/1971118656919830596) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-25T07:44Z 30.9K followers, 2126 engagements "LOL that was quick" [X Link](https://x.com/JacobPlieth/status/1971573097573851440) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-26T13:50Z 30.9K followers, 18.2K engagements "43 patients' worth of data = $8bn of which $5.5bn is being financed through debt $MRUS $GMAB" [X Link](https://x.com/JacobPlieth/status/1972611899255873631) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-29T10:38Z 30.9K followers, 16.6K engagements "Especially for the science nerds I looked at $AZN's latest attempt at CD8-guided T-cell engagement which seems to be a new take on the Titan planform. Via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1973733499749421391) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-02T12:55Z 30.9K followers, 4557 engagements "#ESMO25 Sunday late-breakers: LBA20 - $GILD Ascent-03 "One LBA TBC" LBA21 - unassigned $DSNKY $AZN" [X Link](https://x.com/JacobPlieth/status/1975117046531977337) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-06T08:32Z 30.9K followers, 6966 engagements "So. no $MRNA activity in PD-L1-negatives looks like a win for $IOBT no #ESMO25" [X Link](https://x.com/JacobPlieth/status/1977690767574413571) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T10:59Z 30.9K followers, 10.6K engagements "#ESMO25 regular abstracts are now live with first-in-human data being revealed by $LLY $INCY $DSNKY $MRNA $NVS Parabilis & others. Preview via @ApexOnco" [X Link](https://x.com/JacobPlieth/status/1977743598129926308) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T14:29Z 30.9K followers, 6362 engagements "Napistar1-01 data from Tubulis's TUB-040 coming at an #ESMO25 late-breaker. Meanwhile Tubulis just closed a 308m series C which it claims is the largest series C for a European biotech ever" [X Link](https://x.com/JacobPlieth/status/1978393122263412923) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-15T09:30Z 30.9K followers, 4574 engagements "How bad was $RHHBY Skyscraper-07 Adding Tigit to PD-L1 + chemo actually shortened survival (prob owing to more AEs). Question now: does Tecentriq + chemo (without tira) have a future in this setting #ESMO25" [X Link](https://x.com/JacobPlieth/status/1978736114006388877) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-16T08:13Z 30.9K followers, 3289 engagements "V early solid tumour data for Synnovation's Parp1 inhibitor SNV1521 via Pat LoRusso #ESMO25 $AZN $GILD $MKGAF" [X Link](https://x.com/JacobPlieth/status/1979193474214670481) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-17T14:31Z 30.9K followers, 2809 engagements "@raffcolo You saw this detail Gr5 events include X x ILD X x respiratory tract infection X x acute respiratory faillure X x ARDS. Adjuvant setting $DSNKY $AZN #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979573764791652681) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T15:42Z 30.9K followers, XXX engagements "How did $AZN Potomac readout match $PFE Crest almost number for number Plus a #sadtrombone for Tecentriq in $RHHBY Alban from #ESMO25 yesterday via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1979589056502841635) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T16:43Z 30.9K followers, 2166 engagements "And here's one of the last two men standing in #tigit $RCUS $GILD domvanalimab: first disclosure of OS curves from Edge-Gastric via Yelena Janjigian #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979593749672915069) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T17:01Z 30.9K followers, 2393 engagements "Someone at $AZN might be getting fired for failing to organise a standing ovation for Destiny-Breast05 & XX #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979599455071478251) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T17:24Z 30.9K followers, 11.6K engagements "@ohadhammer Apparently no PFS data on torvuta-S which $AZN had promised in the #ESMO25 abstract" [X Link](https://x.com/JacobPlieth/status/1979878792685666503) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T11:54Z 30.9K followers, XXX engagements "$LLY (ex Mablink) anti-FR ADC LY4170156 starts phase X this month $ABBV $GMAB $STRO" [X Link](https://x.com/JacobPlieth/status/1787773937142653204) [@JacobPlieth](/creator/x/JacobPlieth) 2024-05-07T09:18Z 30.9K followers, 3369 engagements "Keep them coming big pharma $AZN" [X Link](https://x.com/JacobPlieth/status/1976560869464039797) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-10T08:10Z 30.9K followers, 3175 engagements "So basically $SNY is a pioneer" [X Link](https://x.com/JacobPlieth/status/1976617227169489195) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-10T11:54Z 30.9K followers, 5738 engagements "$MRNA mRNA-4359 at #ESMO25: ORR XX% (n=9) but no activity at all in PD-L1 non-expressers (n=13) $IOBT" [X Link](https://x.com/JacobPlieth/status/1977669398149427663) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T09:35Z 30.9K followers, 3594 engagements "Meanwhile here's Skyscraper-03 stage III NSCLC. #tigit combo is no better than Imfinzi but adds tox. No attempt by Rafal Dziaduszko to gloss over how bad these data are #ESMO25 $RHHBY $RCUS $GILD $AZN" [X Link](https://x.com/JacobPlieth/status/1979572793869017474) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T15:38Z 30.9K followers, 2091 engagements "Almost the last #tigit standing: $RCUS $GILD domvanalimab flies the flag at #ESMO25. Via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1979801959264866426) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T06:49Z 30.9K followers, 1786 engagements "Pretty decent #ESMO25 data for $LLY Mablink-derived FR ADC LY4170156 which is about to go into phase X. XX% ORR in FR 0-24% expressers $GILD $ABBV $AZN" [X Link](https://x.com/JacobPlieth/status/1979811830295040264) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T07:28Z 30.9K followers, 3377 engagements "Meanwhile here's $AZN FR ADC torvutatug samrotecan in first-in-human Fontana study. No clear cut by FR expression #ESMO25 via Ana Oaknin" [X Link](https://x.com/JacobPlieth/status/1979834467411010011) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T08:58Z 30.9K followers, 1135 engagements "Something tells me $GMAB is about to get eclipsed in folate receptor alpha ADC $LLY $AZN #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979890827871896039) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T12:42Z 30.9K followers, 1250 engagements "Radiance Biopharma has links to $SGEN and last year licensed Biocytogen's anti-HER2 x TROP2 bispecific ADC YH012/RB-201. Now it's the latest to get into ROR1 $IPN.PA $STRO $ZLAB $ZNTL $IMNM" [X Link](https://x.com/JacobPlieth/status/1892149793750741233) [@JacobPlieth](/creator/x/JacobPlieth) 2025-02-19T09:50Z 30.9K followers, 3568 engagements "Fascinating Evercore ISI webinar going on right now about disconnect between value of Sino deal and what $MRK owes Lanova on the PD-1 x VEGF. In summary: XX% of $588m MRK up front and XX% of the $300m tech transfer actually went to Genscript () $LEGN" [X Link](https://x.com/JacobPlieth/status/1946199171704242199) [@JacobPlieth](/creator/x/JacobPlieth) 2025-07-18T13:23Z 30.8K followers, 11.4K engagements "#WCLC25 late-breaker & plenary preview via @ApexOnco $SMMT $BMY $BNTX $NUVL $CGEM" [X Link](https://x.com/JacobPlieth/status/1958202262183940590) [@JacobPlieth](/creator/x/JacobPlieth) 2025-08-20T16:19Z 30.9K followers, 17.1K engagements "Plus some other #WCLC25 presentations of note: $LEGN $TIL $NVS $BNTX $CADL" [X Link](https://x.com/JacobPlieth/status/1958616455509155996) [@JacobPlieth](/creator/x/JacobPlieth) 2025-08-21T19:45Z 30.8K followers, 5328 engagements "In 2023 $NVS paid $LEGN $100m for an anti-DLL3 Car-T. First human data at #WCLC25 show that this still a work in progress. Via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1965744103523811398) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-10T11:48Z 30.8K followers, 5823 engagements "Interesting take on the FcRH5 landscape which seems to be one of $RHHBY's main oncology R&D areas of interest. $MRNA & $LEGN active here" [X Link](https://x.com/JacobPlieth/status/1970769553572454869) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-24T08:37Z 30.8K followers, 4478 engagements "@jeromeleonard5 @NotthatkindofDr GSK4418959 / IDE275 I was kind of hoping to see FIH data on that at #ESMO25 $GSK $IDYA" [X Link](https://x.com/JacobPlieth/status/1977739462793674925) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T14:13Z 30.8K followers, XXX engagements "@jeromeleonard5 @NotthatkindofDr At #Jefferies24 $IDYA said data were expected at a medical conf in 2025 if I recall" [X Link](https://x.com/JacobPlieth/status/1977740870184050892) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T14:19Z 30.8K followers, XXX engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@JacobPlieth Jacob Plieth
Jacob Plieth posts on X about $azn, $gild, $mrna, $dsnky the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXXX engagements in the last XX hours.
Engagements: XXXXXX #
- X Week XXXXXX +1.90%
- X Month XXXXXXX +21%
- X Months XXXXXXXXX +14%
- X Year XXXXXXXXX -XX%
Mentions: XX #
- X Week XX no change
- X Month XX -X%
- X Months XXX -XX%
- X Year XXX +5.50%
Followers: XXXXXX #
- X Week XXXXXX +0.19%
- X Month XXXXXX +1.10%
- X Months XXXXXX +6.50%
- X Year XXXXXX +12%
CreatorRank: XXXXXXX #
Social Influence #
Social category influence stocks #5305 currencies #774 finance XXXX% cryptocurrencies XXXX%
Social topic influence $azn #3, $gild #1, $mrna #9, $dsnky #2, $lly #5, $rhhby #1, $legn 1.06%, $iobt #1, $bmy #18, $abbv #3
Top accounts mentioned or mentioned by @apexonco @applehelix @bymadeleinea @bertrandbio @drpaulydesantis @notgenentech @maverickny @persimmonti @evaluatevantage @notthatkindofdr @biotechobserver @tman1138pm @avidresearch @phoenicianstrat @jeromeleonard5 @jq1234t @garbageman1985 @evaluatepharma @raffcolo @adamfeuerstein
Top assets mentioned AstraZeneca PLC (AZN) Gilead Sciences, Inc. (GILD) Moderna Inc (MRNA) Eli Lilly and Company (LLY) Bristol-Myers Squibb Co (BMY) AbbVie Inc (ABBV) Novartis AG (NVS) Amgen, Inc. (AMGN) Synthetify (SNY) One Cash (ONC) Summit Therapeutics Inc. Common Stock (SMMT) IDEAYA Biosciences, Inc. Common Stock (IDYA) Arvinas, Inc (ARVN) Revolution Medicines, Inc. Common Stock (RVMD) Merus N.V. Common Shares (MRUS) Incyte Corporation (INCY) Pfizer, Inc. (PFE) Seagen Inc (SGEN) Merck & Co., Inc. (MRK) Nuvalent, Inc. Class A Common Stock (NUVL) Hundred Million (100M) GSK plc (GSK)
Top Social Posts #
Top posts by engagements in the last XX hours
"Wow so $AMGN slipped out that bemarituzumab's positive final OS analysis slipped into negative territory at longer follow-up. $ZLAB off X% yesterday -X% premarket today"
X Link @JacobPlieth 2025-09-04T08:50Z 30.9K followers, 8709 engagements
"$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24"
X Link @JacobPlieth 2024-12-10T23:46Z 30.9K followers, 7600 engagements
"#ESMO25 late-breaker LBA53 but now $IOBT says it can't file on IOB-013 study"
X Link @JacobPlieth 2025-09-29T11:09Z 30.9K followers, 15.6K engagements
"Now $BMY buys Orbital for. $1.5bn Focus seems to be autoimmune but pipeline also includes some oncology work $AZN $ABBV $GILD $SNY $ALPMF"
X Link @JacobPlieth 2025-10-10T11:19Z 30.9K followers, 14.2K engagements
"Is this a world record Seven days from data toplining to appearance in an #ESMO25 late-breaker $AZN"
X Link @JacobPlieth 2025-10-13T08:52Z 30.9K followers, 3600 engagements
"So the ILD grading shenanigans continue. Here's another grade X event adjudicated as grade X ILD $DSNKY $AZN #ESMO25"
X Link @JacobPlieth 2025-10-19T10:03Z 30.9K followers, 2034 engagements
"New phase X Parp1 inhibitor from Synnovation $MKGAF $GILD $AZN"
X Link @JacobPlieth 2024-01-30T13:34Z 30.9K followers, 7612 engagements
"First patient now dosed in this study of TUB-040 Tubulis says. Relevant for $ZYME $ADCT $MRSN & MediLink"
X Link @JacobPlieth 2024-06-20T14:14Z 30.9K followers, 4326 engagements
"Catching up on some #ASCO25 sessions I came across this on dual-payload ADCs from Patricia LoRusso's clinical science symposium"
X Link @JacobPlieth 2025-06-06T13:09Z 30.9K followers, 6665 engagements
"$AMGN Fortitude-101 study of bemarituzumab (ex $FPRX) + chemo is stat sig "& clinically meaningful" for OS vs chemo alone. FGFR2boverexpression (10% @ IHC 2+/3+) was enrolment criterion I believe so this is a hit on ITT. $TYRA"
X Link @JacobPlieth 2025-06-30T13:09Z 30.9K followers, 2801 engagements
"You already have a small-molecule inhibitor so do you also need a degrader $ONC $BGNE thinks yes for BTK CDK2 & Kras. Via @ApexOnco - $ARVN $GILD $RVMD"
X Link @JacobPlieth 2025-06-30T14:45Z 30.9K followers, 4695 engagements
"More doubts for $SMMT as the Harmoni guessing game continues at #WCLC25. Via @ApexOnco - $BNTX $TIL $BMY"
X Link @JacobPlieth 2025-09-07T19:23Z 30.9K followers, 11.4K engagements
"First $AFMD now $IPHA. what say $ONC & any others still involved in NK-cell engagers"
X Link @JacobPlieth 2025-09-17T13:16Z 30.9K followers, 5042 engagements
"New players in dual-payload ADCs: Lonza Synaffix & Qurient Therapeutics. CDK7 inhibitor"
X Link @JacobPlieth 2025-09-25T07:44Z 30.9K followers, 2126 engagements
"LOL that was quick"
X Link @JacobPlieth 2025-09-26T13:50Z 30.9K followers, 18.2K engagements
"43 patients' worth of data = $8bn of which $5.5bn is being financed through debt $MRUS $GMAB"
X Link @JacobPlieth 2025-09-29T10:38Z 30.9K followers, 16.6K engagements
"Especially for the science nerds I looked at $AZN's latest attempt at CD8-guided T-cell engagement which seems to be a new take on the Titan planform. Via @ApexOnco -"
X Link @JacobPlieth 2025-10-02T12:55Z 30.9K followers, 4557 engagements
"#ESMO25 Sunday late-breakers: LBA20 - $GILD Ascent-03 "One LBA TBC" LBA21 - unassigned $DSNKY $AZN"
X Link @JacobPlieth 2025-10-06T08:32Z 30.9K followers, 6966 engagements
"So. no $MRNA activity in PD-L1-negatives looks like a win for $IOBT no #ESMO25"
X Link @JacobPlieth 2025-10-13T10:59Z 30.9K followers, 10.6K engagements
"#ESMO25 regular abstracts are now live with first-in-human data being revealed by $LLY $INCY $DSNKY $MRNA $NVS Parabilis & others. Preview via @ApexOnco"
X Link @JacobPlieth 2025-10-13T14:29Z 30.9K followers, 6362 engagements
"Napistar1-01 data from Tubulis's TUB-040 coming at an #ESMO25 late-breaker. Meanwhile Tubulis just closed a 308m series C which it claims is the largest series C for a European biotech ever"
X Link @JacobPlieth 2025-10-15T09:30Z 30.9K followers, 4574 engagements
"How bad was $RHHBY Skyscraper-07 Adding Tigit to PD-L1 + chemo actually shortened survival (prob owing to more AEs). Question now: does Tecentriq + chemo (without tira) have a future in this setting #ESMO25"
X Link @JacobPlieth 2025-10-16T08:13Z 30.9K followers, 3289 engagements
"V early solid tumour data for Synnovation's Parp1 inhibitor SNV1521 via Pat LoRusso #ESMO25 $AZN $GILD $MKGAF"
X Link @JacobPlieth 2025-10-17T14:31Z 30.9K followers, 2809 engagements
"@raffcolo You saw this detail Gr5 events include X x ILD X x respiratory tract infection X x acute respiratory faillure X x ARDS. Adjuvant setting $DSNKY $AZN #ESMO25"
X Link @JacobPlieth 2025-10-18T15:42Z 30.9K followers, XXX engagements
"How did $AZN Potomac readout match $PFE Crest almost number for number Plus a #sadtrombone for Tecentriq in $RHHBY Alban from #ESMO25 yesterday via @ApexOnco -"
X Link @JacobPlieth 2025-10-18T16:43Z 30.9K followers, 2166 engagements
"And here's one of the last two men standing in #tigit $RCUS $GILD domvanalimab: first disclosure of OS curves from Edge-Gastric via Yelena Janjigian #ESMO25"
X Link @JacobPlieth 2025-10-18T17:01Z 30.9K followers, 2393 engagements
"Someone at $AZN might be getting fired for failing to organise a standing ovation for Destiny-Breast05 & XX #ESMO25"
X Link @JacobPlieth 2025-10-18T17:24Z 30.9K followers, 11.6K engagements
"@ohadhammer Apparently no PFS data on torvuta-S which $AZN had promised in the #ESMO25 abstract"
X Link @JacobPlieth 2025-10-19T11:54Z 30.9K followers, XXX engagements
"$LLY (ex Mablink) anti-FR ADC LY4170156 starts phase X this month $ABBV $GMAB $STRO"
X Link @JacobPlieth 2024-05-07T09:18Z 30.9K followers, 3369 engagements
"Keep them coming big pharma $AZN"
X Link @JacobPlieth 2025-10-10T08:10Z 30.9K followers, 3175 engagements
"So basically $SNY is a pioneer"
X Link @JacobPlieth 2025-10-10T11:54Z 30.9K followers, 5738 engagements
"$MRNA mRNA-4359 at #ESMO25: ORR XX% (n=9) but no activity at all in PD-L1 non-expressers (n=13) $IOBT"
X Link @JacobPlieth 2025-10-13T09:35Z 30.9K followers, 3594 engagements
"Meanwhile here's Skyscraper-03 stage III NSCLC. #tigit combo is no better than Imfinzi but adds tox. No attempt by Rafal Dziaduszko to gloss over how bad these data are #ESMO25 $RHHBY $RCUS $GILD $AZN"
X Link @JacobPlieth 2025-10-18T15:38Z 30.9K followers, 2091 engagements
"Almost the last #tigit standing: $RCUS $GILD domvanalimab flies the flag at #ESMO25. Via @ApexOnco -"
X Link @JacobPlieth 2025-10-19T06:49Z 30.9K followers, 1786 engagements
"Pretty decent #ESMO25 data for $LLY Mablink-derived FR ADC LY4170156 which is about to go into phase X. XX% ORR in FR 0-24% expressers $GILD $ABBV $AZN"
X Link @JacobPlieth 2025-10-19T07:28Z 30.9K followers, 3377 engagements
"Meanwhile here's $AZN FR ADC torvutatug samrotecan in first-in-human Fontana study. No clear cut by FR expression #ESMO25 via Ana Oaknin"
X Link @JacobPlieth 2025-10-19T08:58Z 30.9K followers, 1135 engagements
"Something tells me $GMAB is about to get eclipsed in folate receptor alpha ADC $LLY $AZN #ESMO25"
X Link @JacobPlieth 2025-10-19T12:42Z 30.9K followers, 1250 engagements
"Radiance Biopharma has links to $SGEN and last year licensed Biocytogen's anti-HER2 x TROP2 bispecific ADC YH012/RB-201. Now it's the latest to get into ROR1 $IPN.PA $STRO $ZLAB $ZNTL $IMNM"
X Link @JacobPlieth 2025-02-19T09:50Z 30.9K followers, 3568 engagements
"Fascinating Evercore ISI webinar going on right now about disconnect between value of Sino deal and what $MRK owes Lanova on the PD-1 x VEGF. In summary: XX% of $588m MRK up front and XX% of the $300m tech transfer actually went to Genscript () $LEGN"
X Link @JacobPlieth 2025-07-18T13:23Z 30.8K followers, 11.4K engagements
"#WCLC25 late-breaker & plenary preview via @ApexOnco $SMMT $BMY $BNTX $NUVL $CGEM"
X Link @JacobPlieth 2025-08-20T16:19Z 30.9K followers, 17.1K engagements
"Plus some other #WCLC25 presentations of note: $LEGN $TIL $NVS $BNTX $CADL"
X Link @JacobPlieth 2025-08-21T19:45Z 30.8K followers, 5328 engagements
"In 2023 $NVS paid $LEGN $100m for an anti-DLL3 Car-T. First human data at #WCLC25 show that this still a work in progress. Via @ApexOnco -"
X Link @JacobPlieth 2025-09-10T11:48Z 30.8K followers, 5823 engagements
"Interesting take on the FcRH5 landscape which seems to be one of $RHHBY's main oncology R&D areas of interest. $MRNA & $LEGN active here"
X Link @JacobPlieth 2025-09-24T08:37Z 30.8K followers, 4478 engagements
"@jeromeleonard5 @NotthatkindofDr GSK4418959 / IDE275 I was kind of hoping to see FIH data on that at #ESMO25 $GSK $IDYA"
X Link @JacobPlieth 2025-10-13T14:13Z 30.8K followers, XXX engagements
"@jeromeleonard5 @NotthatkindofDr At #Jefferies24 $IDYA said data were expected at a medical conf in 2025 if I recall"
X Link @JacobPlieth 2025-10-13T14:19Z 30.8K followers, XXX engagements