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# ![@JacobPlieth Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::873399943.png) @JacobPlieth Jacob Plieth

Jacob Plieth posts on X about $azn, $mrk, $pfe, $bmy the most. They currently have [------] followers and [---] posts still getting attention that total [-----] engagements in the last [--] hours.

### Engagements: [-----] [#](/creator/twitter::873399943/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::873399943/c:line/m:interactions.svg)

- [--] Week [------] +65%
- [--] Month [-------] -34%
- [--] Months [---------] +35%
- [--] Year [---------] -16%

### Mentions: [--] [#](/creator/twitter::873399943/posts_active)
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- [--] Week [--] +5.70%
- [--] Month [---] -50%
- [--] Months [---] +58%
- [--] Year [-----] +6.90%

### Followers: [------] [#](/creator/twitter::873399943/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::873399943/c:line/m:followers.svg)

- [--] Week [------] +0.22%
- [--] Month [------] +0.65%
- [--] Months [------] +4.90%
- [--] Year [------] +12%

### CreatorRank: [-------] [#](/creator/twitter::873399943/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::873399943/c:line/m:influencer_rank.svg)

### Social Influence

**Social category influence**
[stocks](/list/stocks)  82.32% [currencies](/list/currencies)  16.02% [cryptocurrencies](/list/cryptocurrencies)  14.36% [finance](/list/finance)  3.87% [technology brands](/list/technology-brands)  2.21% [countries](/list/countries)  0.55%

**Social topic influence**
[$azn](/topic/$azn) #35, [$mrk](/topic/$mrk) #77, [$pfe](/topic/$pfe) #196, [$bmy](/topic/$bmy) #12, [$lly](/topic/$lly) #64, [$jnj](/topic/$jnj) #53, [$onc](/topic/$onc) #3, [$abbv](/topic/$abbv) #30, [$nrix](/topic/$nrix) #4, [$bdtx](/topic/$bdtx) #13

**Top accounts mentioned or mentioned by**
[@apexonco](/creator/undefined) [@evaluatepharma](/creator/undefined) [@lionswatson](/creator/undefined) [@bymadeleinea](/creator/undefined) [@epvantage](/creator/undefined) [@byjofagg](/creator/undefined) [@charleneliao](/creator/undefined) [@garbageman1985](/creator/undefined) [@financebully](/creator/undefined) [@egidiuslambrech](/creator/undefined) [@octopusking77](/creator/undefined) [@applehelix](/creator/undefined) [@samfazeli8](/creator/undefined) [@profoak](/creator/undefined) [@ablt315i](/creator/undefined) [@notgenentech](/creator/undefined) [@bioinvestor24](/creator/undefined) [@raffcolo](/creator/undefined) [@ayishasharma97](/creator/undefined) [@zacharybrennan](/creator/undefined)

**Top assets mentioned**
[AstraZeneca PLC (AZN)](/topic/$azn) [Merck & Co., Inc. (MRK)](/topic/$mrk) [Pfizer, Inc. (PFE)](/topic/$pfe) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [Eli Lilly and Company (LLY)](/topic/$lly) [Johnson & Johnson (JNJ)](/topic/$jnj) [One Cash (ONC)](/topic/$onc) [AbbVie Inc (ABBV)](/topic/$abbv) [Nurix Therapeutics, Inc. (NRIX)](/topic/$nrix) [Black Diamond Therapeutics Inc. (BDTX)](/topic/$bdtx) [Novartis AG (NVS)](/topic/$nvs) [Terns Pharmaceuticals, Inc. (TERN)](/topic/$tern) [Incyte Corporation (INCY)](/topic/$incy) [Arcellx, Inc. (ACLX)](/topic/$aclx) [Gilead Sciences, Inc. (GILD)](/topic/$gild) [Enliven Therapeutics, Inc. (ELVN)](/topic/$elvn) [Synthetify (SNY)](/topic/$sny) [Seagen Inc (SGEN)](/topic/$sgen) [Arcus Biosciences, Inc. (RCUS)](/topic/$rcus) [GSK plc (GSK)](/topic/$gsk) [ArriVent BioPharma, Inc.  (AVBP)](/topic/$avbp) [Instil Bio, Inc. (TIL)](/topic/$til) [Novo-Nordisk (NVO)](/topic/$nvo) [Summit Therapeutics Inc. Common Stock (SMMT)](/topic/$smmt) [Legend Biotech Corp (LEGN)](/topic/$legn) [Oric Pharmaceuticals, Inc. (ORIC)](/topic/$oric) [Jazz Pharmaceuticals, Inc. (JAZZ)](/topic/$jazz) [Maker (MKR)](/topic/$mkr) [PTC Therapeutics, Inc. (PTCT)](/topic/$ptct) [Exelixis Inc (EXEL)](/topic/$exel) [Allora (ALLO)](/topic/$allo) [CRISPR Therapeutics AG (CRSP)](/topic/$crsp) [Caribou Biosciences, Inc. (CRBU)](/topic/$crbu) [Abivax SA (ABVX)](/topic/$abvx) [Kairos Pharma, Ltd. (KAPA)](/topic/$kapa) [iTeos Therapeutics, Inc. (ITOS)](/topic/$itos) [Janux Therapeutics, Inc. (JANX)](/topic/$janx) [Sanofi (SNY)](/topic/sanofi) [CG Oncology, Inc.  (CGON)](/topic/$cgon) [Vir Biotechnology, Inc. Common Stock (VIR)](/topic/$vir) [Kyverna Therapeutics, Inc. (KYTX)](/topic/$kytx) [Axion (AXN)](/topic/axion) [Moderna Inc (MRNA)](/topic/$mrna) [Kinnate Biopharma Inc. (KNTE)](/topic/$knte)
### Top Social Posts
Top posts by engagements in the last [--] hours

"Is it a reverse merger Is it a fund raising I've tried to decipher the $TPST Factor deal which is structured to avoid litigation vs $CLLS & $AZN. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1740 https://www.oncologypipeline.com/apexonco/node/1740"  
[X Link](https://x.com/JacobPlieth/status/1991504198048051676)  2025-11-20T13:49Z 31.7K followers, [----] engagements


"After $RHHBY #Tigit failed in Skyscraper-14 $RCYS $GILD terminate Star-221 for futility. Evidently someone was surprsed as $RCUS is -12% PM"  
[X Link](https://x.com/JacobPlieth/status/1999478856760348860)  2025-12-12T13:58Z 31.7K followers, [----] engagements


"If $ABBV BTK degrader ABBV-101 has been discontinued (Evercore ISI confirms to us that it has) that's good news for $ONC & $NRIX - https://www.oncologypipeline.com/apexonco/node/1893/ https://www.oncologypipeline.com/apexonco/node/1893/"  
[X Link](https://x.com/JacobPlieth/status/2019799696605069482)  2026-02-06T15:45Z 31.8K followers, [----] engagements


"The power of groupthink"  
[X Link](https://x.com/JacobPlieth/status/2021622349099864320)  2026-02-11T16:28Z 31.7K followers, [----] engagements


"Quick reminder: I make that [----] patients on late-stage rilvegostomig trials $AZN $GILD $RCUS #tigit"  
[X Link](https://x.com/JacobPlieth/status/1986358119316754833)  2025-11-06T09:00Z 31.8K followers, [----] engagements


"By my calculation $ONC now has an efficacy edge vs $NRIX in BTK degradation. Caveats: small pt numbers X-trial comparison and Nurix might have the safety advantage #ASH25"  
[X Link](https://x.com/JacobPlieth/status/1997987562455978162)  2025-12-08T11:12Z 31.8K followers, [----] engagements


"And here's what $AZN has in store for AZD0120 via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1903 https://www.oncologypipeline.com/apexonco/node/1903"  
[X Link](https://x.com/JacobPlieth/status/2021609050073407567)  2026-02-11T15:35Z 31.8K followers, [----] engagements


"Car-T therapy in 3rd-line DLBCL $DTIL $ACET $ALLO $CRSP $CRBU"  
[X Link](https://x.com/anyuser/status/1743237406751703520)  2024-01-05T11:46Z 31.8K followers, 18.7K engagements


"PD-1 x VEGF meet CD47 Ivonescimab +/- ligufalimab + chemo in 1L (not dMMR) colorectal. 88% ORR. China study obv. Via Yanhong Deng #ESMO24 $SMMT $BNTX"  
[X Link](https://x.com/anyuser/status/1834956549187330553)  2024-09-14T14:05Z 31.8K followers, 23.1K engagements


"@AppleHelix Surely not. $ABVX"  
[X Link](https://x.com/JacobPlieth/status/2022004569702903944)  2026-02-12T17:47Z 31.8K followers, [----] engagements


"$KAPA reports 13mth mPFS for carotuximab + Erleada (n=8 excluding [--] patients because reasons) but somehow omits to say anything about the control arm of Erleada monotherapy. Off 17%"  
[X Link](https://x.com/JacobPlieth/status/1968711416816300517)  2025-09-18T16:19Z 31.7K followers, [----] engagements


"I thought we were expecting $BDTX to reveal what regulatory pathway it's planning for silevertinib"  
[X Link](https://x.com/JacobPlieth/status/1996194013226148056)  2025-12-03T12:25Z 31.7K followers, [----] engagements


"@LionsWatson .but do feel free to use this as a "buying opportunity" LOL $BDTX"  
[X Link](https://x.com/JacobPlieth/status/1996229273615466968)  2025-12-03T14:45Z 31.7K followers, [----] engagements


"$ELVN vs $TERN: game over #ASH25"  
[X Link](https://x.com/JacobPlieth/status/1998347681236766921)  2025-12-09T11:03Z 31.7K followers, [----] engagements


"So where does this the #tigit Fc debate Fc-active: $GSK $ITOS fail $MRK fail $RHHBY fail Fc-silent: $RCUS $GILD fail Fc-reduced: $AZN $CGEN"  
[X Link](https://x.com/JacobPlieth/status/1999495253091582301)  2025-12-12T15:03Z 31.7K followers, [----] engagements


"Control in $INCY Frontmind (1st-line DLBCL) is R-Chop not Revlimid + R-Chop. So how do we know the (modest) PFS benefit toplined today is due to $INCY Monjuvi and not to Revlimid"  
[X Link](https://x.com/JacobPlieth/status/2008190204503531703)  2026-01-05T14:53Z 31.7K followers, [----] engagements


"OK then let's play the "selected doses" game $ELVN $TERN"  
[X Link](https://x.com/JacobPlieth/status/2009564719955460275)  2026-01-09T09:55Z 31.7K followers, [----] engagements


"Notable that $ELVN didn't split out the 60mg from the 120mg results. Did 60mg actually do better than 80mg All quite bizarre but stock +50% so what do I know $TERN"  
[X Link](https://x.com/JacobPlieth/status/2009565897095336398)  2026-01-09T10:00Z 31.7K followers, [----] engagements


"Looks like $SNY discontinued Alphamedix/ SAR447873 licensed in Sep [----] from Radiomedix & Orano Med h/t B Riley. @ByMadeleineA covered it at #Esmo25 and flagged dysphagia & renal tox. Good news for $CATX https://www.oncologypipeline.com/apexonco/esmo-2025-sanofi-takes-aim-lutathera https://www.oncologypipeline.com/apexonco/esmo-2025-sanofi-takes-aim-lutathera"  
[X Link](https://x.com/JacobPlieth/status/2016894769570456029)  2026-01-29T15:22Z 31.7K followers, [----] engagements


"With a tipoff from a friend and some info that probably shouldn't have been posted in a trial registry the mechanisms of ADCs JNJ-95437446 $JNJ & SKB571/ MK-2750 $MRK have been revealed. Quite amazing given the recent $GMAB news. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1874 https://www.oncologypipeline.com/apexonco/node/1874"  
[X Link](https://x.com/JacobPlieth/status/2016896251233534381)  2026-01-29T15:28Z 31.7K followers, [----] engagements


"Remember MK-2750 which $MRK licensed from Kelun First revealed under the code SKB571 during #Esmo24 https://x.com/JacobPlieth/status/1838465517524320454 I just had confirmation from $MRK that MK-2750 = SKB571. Target still undisclosed. https://x.com/JacobPlieth/status/1838465517524320454 I just had confirmation from $MRK that MK-2750 = SKB571. Target still undisclosed"  
[X Link](https://x.com/JacobPlieth/status/2016896801035440480)  2026-01-29T15:30Z 31.7K followers, [----] engagements


"MK-2750 has been in the clinic since [----]. JNJ-95437446 started phase [--] in July [----] $MRK $JNJ https://www.oncologypipeline.com/apexonco/more-conjugates-pile-clinic https://www.oncologypipeline.com/apexonco/more-conjugates-pile-clinic"  
[X Link](https://x.com/JacobPlieth/status/2016897556660326564)  2026-01-29T15:33Z 31.7K followers, [----] engagements


"@charlene_liao @garbageman1985 $EIKN"  
[X Link](https://x.com/JacobPlieth/status/2018616596856713394)  2026-02-03T09:24Z 31.7K followers, [---] engagements


"@charlene_liao @garbageman1985 I'm not sure there's any fund with a direct ownership link to $MRK here. $EIKN"  
[X Link](https://x.com/JacobPlieth/status/2018617828577046776)  2026-02-03T09:29Z 31.7K followers, [---] engagements


"Interesting difference: the corresponding US approval has no restriction to dMMR (remember PFS HR=0.60 in pMMR but [----] in dMMR) $MRK $MRK announced that its PD-1 inhibitor pembrolizumab (Keytruda) has been approved by NMPA for 1L treatment of adult patients with dMMR primary advanced or recurrent endometrial cancer in combination with carboplatin and paclitaxel followed by maintenance therapy with $MRK announced that its PD-1 inhibitor pembrolizumab (Keytruda) has been approved by NMPA for 1L treatment of adult patients with dMMR primary advanced or recurrent endometrial cancer in"  
[X Link](https://x.com/JacobPlieth/status/2019719565417275554)  2026-02-06T10:27Z 31.7K followers, [----] engagements


"@SamFazeli8 15% below the issue price and 55% below the average at which VCs invested. I think the IPO window does indeed remain putative $EIKN"  
[X Link](https://x.com/JacobPlieth/status/2019788705074905492)  2026-02-06T15:02Z 31.7K followers, [----] engagements


"@Prof_Oak_ I'd be surprised if the up-front was more than $100m $LLY"  
[X Link](https://x.com/JacobPlieth/status/2020893156846240232)  2026-02-09T16:10Z 31.7K followers, [---] engagements


"Ascentage just disclosed that it's developing a BTK degrader: APG-3288 apparently just had its US IND cleared $ONC $NRIX"  
[X Link](https://x.com/JacobPlieth/status/2009639705114210787)  2026-01-09T14:53Z 31.8K followers, [----] engagements


"So $LLY not interested in oncology applications of Orna's in vivo Car-T $ABBV $AZN $BMY $GILD"  
[X Link](https://x.com/JacobPlieth/status/2020836983896232058)  2026-02-09T12:27Z 31.7K followers, 11.3K engagements


"Important similarity between $LLY Orna's and $BMY Orbital's approaches to in vivo Car-T"  
[X Link](https://x.com/JacobPlieth/status/2020858293271330973)  2026-02-09T13:52Z 31.7K followers, [----] engagements


"Key late-breakers at Asco #GU26 include Litespark-011 & [---] Keynote-B15. and who's heard of Flare Therapeutics Via @ApexOnco - $MRK $PFE $ALMPF $CGON $VIR https://www.oncologypipeline.com/apexonco/node/1908 https://www.oncologypipeline.com/apexonco/node/1908"  
[X Link](https://x.com/JacobPlieth/status/2021931844355137687)  2026-02-12T12:58Z 31.7K followers, [----] engagements


"New in vivo Car-T player NCI licensing patent for an anti-CD19 in vivo Car-T for autoimmune disease to $KYTX - https://public-inspection.federalregister.gov/2026-02907.pdf https://public-inspection.federalregister.gov/2026-02907.pdf"  
[X Link](https://x.com/JacobPlieth/status/2021946516349333716)  2026-02-12T13:56Z 31.7K followers, [----] engagements


"$SNY deserves congratulations for finding a new CEO whose track record makes Paul Hudson look good. Chapeau"  
[X Link](https://x.com/JacobPlieth/status/2021955082934186152)  2026-02-12T14:30Z 31.7K followers, [----] engagements


"$LEGN quietly making a big push into in vivo Car-T: LVIVO-TaVec100 (CD19 x CD20) LVIVO-TaVec200 (GPRC5D) LVIVO-TaVec400 (target undisclosed) .all recently entered human trials"  
[X Link](https://x.com/JacobPlieth/status/2022045138567274652)  2026-02-12T20:28Z 31.7K followers, [----] engagements


"At last $MRK nemtabrutinib (non-cov BTKi via $ARQL) makes progress in ph3. Third pivotal study head-to-head vs Imbruvica or Calquence (but not Brukinsa) just listed on CTgov $LLY $BGNE https://classic.clinicaltrials.gov/ct2/show/NCT06136559 https://classic.clinicaltrials.gov/ct2/show/NCT06136559"  
[X Link](https://x.com/JacobPlieth/status/1726559817303834956)  2023-11-20T11:15Z 31.7K followers, [----] engagements


"$BGNE -10% $NRIX +8%. I'm puzzled. #ASH24 data: https://x.com/JacobPlieth/status/1866262593217921411 https://x.com/JacobPlieth/status/1866258468157677750 And here's $BGNE's BTK degrader BGB-16673 in CLL. 93% post cov BTK 22% post non-cov BTK. 78% ORR (94% ORR at 200mg) [--] (unrelated) deaths. Via Meghan Thompson #ASH24 $NRIX https://t.co/sWnrnMJ4S4 https://x.com/JacobPlieth/status/1866262593217921411 https://x.com/JacobPlieth/status/1866258468157677750 And here's $BGNE's BTK degrader BGB-16673 in CLL. 93% post cov BTK 22% post non-cov BTK. 78% ORR (94% ORR at 200mg) [--] (unrelated) deaths. Via"  
[X Link](https://x.com/JacobPlieth/status/1866510710269935712)  2024-12-10T15:50Z 31.7K followers, 19K engagements


"$DSNKY DS3610 starting phase [--] in October. Sting agonist payload ADC (targets still unknown - any ideas) https://clinicaltrials.gov/study/NCT07159126 https://clinicaltrials.gov/study/NCT07159126"  
[X Link](https://x.com/JacobPlieth/status/1967508062375494005)  2025-09-15T08:37Z 31.8K followers, [----] engagements


"First $AFMD now $IPHA. what say $ONC & any others still involved in NK-cell engagers Hopes dim for $IPHA NK-cell engagers https://t.co/81ywllXRUS Hopes dim for $IPHA NK-cell engagers https://t.co/81ywllXRUS"  
[X Link](https://x.com/JacobPlieth/status/1968302921881370818)  2025-09-17T13:16Z 31.7K followers, [----] engagements


"3 new patients zero new responses. Quick take on $ORIC via @Apexonco - https://www.oncologypipeline.com/apexonco/node/1728 https://www.oncologypipeline.com/apexonco/node/1728"  
[X Link](https://x.com/JacobPlieth/status/1989362267964719418)  2025-11-14T15:58Z 31.8K followers, [----] engagements


".or is this the regulatory update: no accelerated pathway needs pivotal trial and $BDTX can't run this without a partner"  
[X Link](https://x.com/JacobPlieth/status/1996194793739952507)  2025-12-03T12:28Z 31.8K followers, [----] engagements


"Silevertinib in 1L NSCLC non-classical mutations. Data look decent but $BDTX needs a partner to fund pivotal development"  
[X Link](https://x.com/JacobPlieth/status/1996205902471512275)  2025-12-03T13:12Z 31.8K followers, [----] engagements


"$BDTX currently off 17% (earlier -30%) on yet another strategic pivot. @ApexOnco take on today's silevertinib data $AVBP https://www.oncologypipeline.com/apexonco/node/1767 https://www.oncologypipeline.com/apexonco/node/1767"  
[X Link](https://x.com/JacobPlieth/status/1996253717298110812)  2025-12-03T16:22Z 31.7K followers, [----] engagements


"Beautifully buried discontinuation of acasunlimab by $GMAB yesterday. A disaster that's been a long time coming and remember GMAB went into phase [--] on its own despite $BNTX earlier pulling the plug https://www.oncologypipeline.com/apexonco/another-vote-no-confidence-co-stimulated-bispecifics https://www.oncologypipeline.com/apexonco/another-vote-no-confidence-co-stimulated-bispecifics"  
[X Link](https://x.com/JacobPlieth/status/2006090796068376823)  2025-12-30T19:51Z 31.7K followers, [----] engagements


"That's confirmed now - #GI26 late-breaking abstract LBA285 $JAZZ $ONC $ZYME $JAZZ Ziihera data from Herizon-GEA-01 study coming at #GI26 https://t.co/WkJdU7lmX7 $JAZZ Ziihera data from Herizon-GEA-01 study coming at #GI26 https://t.co/WkJdU7lmX7"  
[X Link](https://x.com/JacobPlieth/status/2007121744130384021)  2026-01-02T16:08Z 31.8K followers, [----] engagements


"How many people had $TIL scrapping the Immuneonco deal discontinuing PD-1 x VEGF and going back to TIL therapeutics on their #JPM26 bingo card"  
[X Link](https://x.com/JacobPlieth/status/2008530104469909660)  2026-01-06T13:24Z 31.7K followers, 11.3K engagements


"And here's Immuneonco's statement on the $TIL discontinuation. Still says nothing about the reason(s) https://x.com/chuminhua432/status/2008835430263984618 ImmuneOnco announced that Axion Bio Inc. a wholly-owned subsidiary of $TIL has decided to discontinue clinical development of IMM2510/AXN-2510. https://t.co/iWwc7oAa8N Axion and ImmuneOnco have entered into an agreement terminating their license and collaboration https://x.com/chuminhua432/status/2008835430263984618 ImmuneOnco announced that Axion Bio Inc. a wholly-owned subsidiary of $TIL has decided to discontinue clinical development of"  
[X Link](https://x.com/JacobPlieth/status/2008837980824469767)  2026-01-07T09:47Z 31.7K followers, [----] engagements


"$EIKN share price averaged over private financings vs at expected IPO. Normally there's a (substantial) step up when companies float. Not in this case"  
[X Link](https://x.com/JacobPlieth/status/2018345545719226579)  2026-02-02T15:27Z 31.7K followers, 12.7K engagements


"$MRK confirming that Interpath-001 study of $MRNA partnered intismeran autogene is "ongoing & fully enrolled". No further guidance as to timing of results due some time in [----]. My earlier take on what to expect: https://www.oncologypipeline.com/apexonco/moderna-investors-prepare-phase-3-reveal https://www.oncologypipeline.com/apexonco/moderna-investors-prepare-phase-3-reveal"  
[X Link](https://x.com/JacobPlieth/status/2018984974876135475)  2026-02-04T09:48Z 31.7K followers, [----] engagements


"Six years after buying Arqule $MRK is talking about nemtabrutinib again. [----] launch possibility $LLY"  
[X Link](https://x.com/JacobPlieth/status/2018985752068034944)  2026-02-04T09:51Z 31.7K followers, [----] engagements


"$DSNKY's first DXd ADC for haematology DS-3790 enters the clinic. As I reported last November: https://www.oncologypipeline.com/apexonco/sutro-goes-back-work https://www.oncologypipeline.com/apexonco/sutro-goes-back-work"  
[X Link](https://x.com/JacobPlieth/status/2019019252359979484)  2026-02-04T12:04Z 31.8K followers, [----] engagements


"$EIKN prices at $18/share to raise $381m at a $972m market cap. Here's @ApexOnco on what this IPO tells us: https://www.oncologypipeline.com/apexonco/node/1891 https://www.oncologypipeline.com/apexonco/node/1891"  
[X Link](https://x.com/JacobPlieth/status/2019391556998852672)  2026-02-05T12:44Z 31.7K followers, [----] engagements


"Who knew that $MRK filing for KN-B96 indication had [--] separate Pdufa dates one for IV and one for SC Keytruda Remember Keytruda Qlex was approved for "most" solid tumour IV indications. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1905 https://www.oncologypipeline.com/apexonco/node/1905"  
[X Link](https://x.com/JacobPlieth/status/2021609933670617202)  2026-02-11T15:39Z 31.8K followers, [----] engagements


"That's from an industry newsletter that just landed in my inbox. Biopharma's R&D crisis summarised in a single quote"  
[X Link](https://x.com/JacobPlieth/status/2021625666089984260)  2026-02-11T16:41Z 31.7K followers, [----] engagements


"$ABBV believes in the world according to GARP and takes livmoniplimab into phase [--] - on zero monoRx activity and lacklustre budigalimab combo data. What can possibly go wrong Via @ApexOnco - https://www.oncologypipeline.com/apexonco/abbvie-sees-world-according-garp https://www.oncologypipeline.com/apexonco/abbvie-sees-world-according-garp"  
[X Link](https://x.com/JacobPlieth/status/1754541446059655220)  2024-02-05T16:24Z 31.8K followers, [----] engagements


"Free money for $XOMA Buys $KNTE for $110m in cash gets cash balance ($180m in Q3 [----] minimum $120m at close) plus a CVR punt on exarafenib https://investors.kinnate.com/news-releases/news-release-details/kinnate-biopharma-inc-enters-agreement-be-acquired-xoma https://investors.kinnate.com/news-releases/news-release-details/kinnate-biopharma-inc-enters-agreement-be-acquired-xoma"  
[X Link](https://x.com/JacobPlieth/status/1758481399835668752)  2024-02-16T13:20Z 31.8K followers, [----] engagements


"$GMAB looked at $STRO but decided instead to pay 5x more for Profoundbio. My take on the $1.8bn acquisition via @ApexOnco - https://www.oncologypipeline.com/apexonco/profoundbio-takeout-shines-light-sutro https://www.oncologypipeline.com/apexonco/profoundbio-takeout-shines-light-sutro"  
[X Link](https://x.com/JacobPlieth/status/1775520273199960101)  2024-04-03T13:46Z 31.7K followers, 33.5K engagements


"$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24"  
[X Link](https://x.com/JacobPlieth/status/1866630560355061773)  2024-12-10T23:46Z 31.7K followers, [----] engagements


"Something tells me $GMAB is about to get eclipsed in folate receptor alpha ADC $LLY $AZN #ESMO25"  
[X Link](https://x.com/JacobPlieth/status/1979890827871896039)  2025-10-19T12:42Z 31.8K followers, [----] engagements


"If you need some biotech reading over Thanksgiving check out @ApexOnco previews of #ASH25 -- Starts in just over a week $ACLX $ONC $CRVS $TERN $KURA $SNDX $CGEM $INCY https://www.oncologypipeline.com/apexonco/search/nodekeys=%22ash+2025%22 https://www.oncologypipeline.com/apexonco/search/nodekeys=%22ash+2025%22"  
[X Link](https://x.com/JacobPlieth/status/1994037961198129381)  2025-11-27T13:37Z 31.8K followers, [----] engagements


"@LionsWatson I'm so sorry for being insufficiently enthusiastic with my praise for $BDTX. Anyway here's $AVBP"  
[X Link](https://x.com/JacobPlieth/status/1996218585740345482)  2025-12-03T14:02Z 31.7K followers, [----] engagements


"$NRIX +23% surprises me. I thought the #ASH25 data showed $ONC to be better on efficacy (with caveats) albeit worse on safety. My earlier take on @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1775 https://www.oncologypipeline.com/apexonco/node/1775"  
[X Link](https://x.com/JacobPlieth/status/1998055411392327821)  2025-12-08T15:41Z 31.7K followers, [----] engagements


"$LLY Jaypirca looks best. up to a point. Via @ApexOnco from #ASH25 $ONC $AZN $JNJ $ABBV $NRIX https://www.oncologypipeline.com/apexonco/node/1772/ https://www.oncologypipeline.com/apexonco/node/1772/"  
[X Link](https://x.com/JacobPlieth/status/1998373428114624578)  2025-12-09T12:45Z 31.8K followers, [----] engagements


"@ablT315I And. here come the sellside notes defending $ACLX"  
[X Link](https://x.com/JacobPlieth/status/1998441028085338596)  2025-12-09T17:14Z 31.8K followers, [---] engagements


"What a stinker of an #ASH25 for $ACLX -16% since Nov abstract drop. Inconsequential Immagine-1 update while others making huge strides"  
[X Link](https://x.com/JacobPlieth/status/1998445251929702548)  2025-12-09T17:30Z 31.8K followers, [----] engagements


"Interesting flurry of activity in LRRC15: $IPN.PA today licensed Simcere's SIM0613 (ADC). $LNTH prepares to take LNTH-2403 (Lu-177 radioTx) into phase [--]. In Jan $ZLAB did deal with Medilink to develop ZL-6201 as an ADC. $ABBV earlier abandoned ph1 samrotamab vedotin"  
[X Link](https://x.com/JacobPlieth/status/2003035721914085491)  2025-12-22T09:31Z 31.8K followers, [----] engagements


"@NotGenentech @bioinvestor24 Here's a list of just the clinical pan-RAS & pan-KRAS assets from Oncologypipeline $RVMD $LLY $ONC $RHHBY $PFE $ERAS $AZN $AMGN $ALPMF"  
[X Link](https://x.com/JacobPlieth/status/2003075475464466829)  2025-12-22T12:09Z 31.7K followers, [---] engagements


"Still not convinced by $ELVN Via @ApexOnco - $TERN https://www.oncologypipeline.com/apexonco/node/1826 https://www.oncologypipeline.com/apexonco/node/1826"  
[X Link](https://x.com/JacobPlieth/status/2009641620116025708)  2026-01-09T15:01Z 31.7K followers, [----] engagements


"Seven days after $TIL pulled the plug Immuneonco says it's still independently developing its PD-L1 x VEGF trap palverafusp alfa $SMMT $BNTX https://mp.weixin.qq.com/s/8mykgEpQrSLXUhDuLa1AJg https://mp.weixin.qq.com/s/8mykgEpQrSLXUhDuLa1AJg"  
[X Link](https://x.com/JacobPlieth/status/2011408172435845573)  2026-01-14T12:00Z 31.7K followers, [----] engagements


"All good still for $ACLX though Carvykti is now a blockbuster with FY [----] sales of 1.9bn from $963m in FY [----] $JNJ Carvykti is now a blockbuster with FY [----] sales of 1.9bn from $963m in FY [----] $JNJ"  
[X Link](https://x.com/JacobPlieth/status/2013965390980731257)  2026-01-21T13:22Z 31.7K followers, [----] engagements


"Several scoops among the latest ADC names. Via @ApexOnco with H/T to @raffcolo - https://www.oncologypipeline.com/apexonco/node/1883/ https://www.oncologypipeline.com/apexonco/node/1883/"  
[X Link](https://x.com/JacobPlieth/status/2018995692254183894)  2026-02-04T10:30Z 31.7K followers, [----] engagements


"Some revelations for ADC nerds: $SNY uses the same MAb in its new CEACAM5 ADC as in the one it discontinued in [----]. Chia Tai claims a deuterated DXd payload (with no link to $DSNKY). $DSNKY TA-MUC1 ADC uses sacomitatug not Glycotope's gatipotuzumab"  
[X Link](https://x.com/JacobPlieth/status/2018996942970188216)  2026-02-04T10:35Z 31.7K followers, [----] engagements


"Confirmned discontinuation of $NVS PIT565 which seems to be a specifically targeted T-cell engager (also hit CD2). cf $AZN Titan platform. There are several projects missing from the $NVS phase [--] pipeline in Q4 (left) vs Q3 (right) plus a couple of new projects https://t.co/NuTJbS8T0p There are several projects missing from the $NVS phase [--] pipeline in Q4 (left) vs Q3 (right) plus a couple of new projects https://t.co/NuTJbS8T0p"  
[X Link](https://x.com/JacobPlieth/status/2019030178866020360)  2026-02-04T12:48Z 31.7K followers, [----] engagements


"What could possibly have gone wrong indeed Looks like $ABBV has all but discontinued the anti-GARP MAb livmoniplimab. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1893/ https://www.oncologypipeline.com/apexonco/node/1893/"  
[X Link](https://x.com/JacobPlieth/status/2019798858532806714)  2026-02-06T15:42Z 31.7K followers, [----] engagements


"Interesting disclosure from $ABBV Q4 presentation: ABBV-901 is an anti-FR ADC - so trying to improve on Elahere given the threats of $GMAB $LLY etc https://clinicaltrials.gov/study/NCT07278336 https://clinicaltrials.gov/study/NCT07278336"  
[X Link](https://x.com/JacobPlieth/status/2020796872890138945)  2026-02-09T09:48Z 31.8K followers, [----] engagements


"Now $ORIC goes after $AVBP & $BDTX in 1st-line PACC lung cancer and shows why it abandoned relapsed HER2 ex20. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1771/ https://www.oncologypipeline.com/apexonco/node/1771/"  
[X Link](https://x.com/JacobPlieth/status/1996942292771365034)  2025-12-05T13:58Z 31.8K followers, [----] engagements


"The enlarged $TPST prioritising a CD19 x BCMA Car-T (TPST-2003) just as $AZN launches its phase [--] study of (ex $GRCL) AZD0120/GC012F: https://clinicaltrials.gov/study/NCT07391657 https://clinicaltrials.gov/study/NCT07391657"  
[X Link](https://x.com/JacobPlieth/status/2021562955083731420)  2026-02-11T12:32Z 31.8K followers, [----] engagements


"Wow check out the $JNJ Tecvayli survival curves in Majestec-3 #ASH25"  
[X Link](https://x.com/JacobPlieth/status/1998377670745403427)  2025-12-09T13:02Z 31.8K followers, [----] engagements


"$JNJ Tecvayli (& $LEGN Carvykti) "entering a new era of resetting survival expectations in a cancer historically described as incurable". @ByMadeleineA @ApexOnco from #ASH25 on Majestec-3 $ACLX $BMY https://www.oncologypipeline.com/apexonco/node/1782 https://www.oncologypipeline.com/apexonco/node/1782"  
[X Link](https://x.com/JacobPlieth/status/1998378577856000306)  2025-12-09T13:05Z 31.8K followers, [----] engagements


"You see @Ayisha_Sharma97 this is how common professional courtesy works. Learn from your colleague @ZacharyBrennan"  
[X Link](https://x.com/JacobPlieth/status/2021700169654309037)  2026-02-11T21:37Z 31.7K followers, 10.2K engagements


"$AZN isn't the only company that still believes in PD-(L)1 x TIGIT: SH006 just went into phase [--] https://clinicaltrials.gov/study/NCT07392866 https://clinicaltrials.gov/study/NCT07392866"  
[X Link](https://x.com/JacobPlieth/status/2022050718623121568)  2026-02-12T20:50Z 31.7K followers, [----] engagements


"Positive for $HNSN $SYK $MAKO $ISRG http://t.co/rrQAMVBfFQ http://phx.corporate-ir.net/phoenix.zhtmlc=118965&p=irol-newsArticle&ID=1857846&highlight= http://phx.corporate-ir.net/phoenix.zhtmlc=118965&p=irol-newsArticle&ID=1857846&highlight="  
[X Link](https://x.com/JacobPlieth/status/382842092147326976)  2013-09-25T12:20Z 27.7K followers, [--] engagements


"While $OREX stock has slumped consensus forecasts for [----] Contrave sales have surged in the past [--] months http://t.co/DKWTlPvGMn"  
[X Link](https://x.com/JacobPlieth/status/404916914691915776)  2013-11-25T10:18Z 27.7K followers, [--] engagements


"Gotlib on relative characteristics of JAK inhibitors $GILD $INCY http://t.co/BSFDHpl5zi"  
[X Link](https://x.com/JacobPlieth/status/409438047806050304)  2013-12-07T21:43Z 27.7K followers, [--] engagements


"How palbociclib's consensus sales forecasts have come up. $AMGN battle for Onyx started in July. $PFE http://t.co/TeE7KolgfO"  
[X Link](https://x.com/JacobPlieth/status/430314070894321664)  2014-02-03T12:17Z 27.7K followers, [--] engagements


"So with $QCOR it's price gouging but with $RTRX it's a smart move understanding the market and providing value. Brilliant"  
[X Link](https://x.com/JacobPlieth/status/433965103948759040)  2014-02-13T14:05Z 27.7K followers, [--] engagements


"Yes folks $BMY has just been asked whether it will be able to compete with $AZN $PFE in immu-onc"  
[X Link](https://x.com/JacobPlieth/status/461143205661376512)  2014-04-29T14:01Z 27.7K followers, [--] engagements


"Bernstein on UK market share of Siemens' hearing aid biz now set for spin-out $SI http://t.co/BEZtwiRWND"  
[X Link](https://x.com/JacobPlieth/status/463957750402535424)  2014-05-07T08:25Z 27.7K followers, [--] engagements


"US VA hearing aid market via Bernstein $SI $SOON $WDH http://t.co/T9wrcVBVaj"  
[X Link](https://x.com/JacobPlieth/status/463958255640006656)  2014-05-07T08:27Z 27.7K followers, [--] engagements


"$LUN not disclosing specific trigger for $CHTP CVRs beyond saying it concerns Northera sales exceeding a base case http://t.co/z0qE07mu9K"  
[X Link](https://x.com/JacobPlieth/status/464377211676794881)  2014-05-08T12:12Z 27.7K followers, [--] engagements


"Good take on $AZN $PFE by @PanmureSavvas http://t.co/wmAS9Mir2u"  
[X Link](https://x.com/JacobPlieth/status/466492413242912768)  2014-05-14T08:17Z 27.7K followers, [--] engagements


"Well played Bryan Garnier $AZN $PFE http://t.co/40Sg8y7d7M"  
[X Link](https://x.com/JacobPlieth/status/466493035082031104)  2014-05-14T08:19Z 27.7K followers, [--] engagements


"$AZN #BTD AZD9291 efficacy in phase I T790M+ NSCLC $CLVS $PFE #ASCO14 http://t.co/wNYWJjZESD"  
[X Link](https://x.com/JacobPlieth/status/466689465155858433)  2014-05-14T21:20Z 27.7K followers, [--] engagements


"Thrombogenics burns through EUR15.5m in three months. Strategic review still ongoing. $THR"  
[X Link](https://x.com/JacobPlieth/status/469511064431120384)  2014-05-22T16:12Z 27.7K followers, [--] engagements


"$ATLN CEO says he was expecting any more patients to discontinue in Griphon given the length of the trial $UTHR"  
[X Link](https://x.com/JacobPlieth/status/478508931816632320)  2014-06-16T12:06Z 27.7K followers, [--] engagements


"$PFE's $ALCLS deal makes Servier (and Orbimed Ridgeback Aquilo VenBio & Merlin Nexus) look super smart"  
[X Link](https://x.com/JacobPlieth/status/479228314775998465)  2014-06-18T11:45Z 27.7K followers, [--] engagements


"Leerink's take on Keytruda off-label use $MRK $BMY #PD1 http://t.co/MkwsptgBcq"  
[X Link](https://x.com/JacobPlieth/status/507829108777050112)  2014-09-05T09:54Z 27.7K followers, [--] engagements


"Fact: [--] months ago odanacatib was $MRK's most valuable R&D asset. How [----] forecast has fallen via @evaluatepharma http://t.co/EwohQUD1V4"  
[X Link](https://x.com/JacobPlieth/status/511427831482834944)  2014-09-15T08:14Z 27.7K followers, [--] engagements


"UBS sees an optimistic read-across to $INCY of the $RHHBY $NLNK IDO deal. http://t.co/P7VanZby4B"  
[X Link](https://x.com/JacobPlieth/status/524200704387608576)  2014-10-20T14:09Z 27.7K followers, [--] engagements


"Prolor (bought by $OPK) was an Israeli company. The $295m non-up-front up-front could be $PFE using up offshore cash"  
[X Link](https://x.com/JacobPlieth/status/544482991809236992)  2014-12-15T13:23Z 27.7K followers, [--] engagements


"UBS on Kalydeco's R117H approval and beyond $VRTX http://t.co/EDedjHIeyo"  
[X Link](https://x.com/JacobPlieth/status/549909723777335296)  2014-12-30T12:47Z 27.7K followers, [--] engagements


"I just spoke to the $CARD CEO. Lead CAR construct (with NKG2D) uses CD3zeta plus DAP10 as a natural co-stim domain http://t.co/ExK8uM2NP6"  
[X Link](https://x.com/JacobPlieth/status/552493665487446019)  2015-01-06T15:55Z 27.7K followers, [--] engagements


"$AZN late-stage oncology highlights http://t.co/avYeGhIrwJ"  
[X Link](https://x.com/JacobPlieth/status/563267227081015296)  2015-02-05T09:25Z 27.7K followers, [--] engagements


"Still a potential big pharma partner is probably better than none and that's what $BAVA has today. $BMY"  
[X Link](https://x.com/JacobPlieth/status/573039938033336320)  2015-03-04T08:39Z 28K followers, [--] engagements


"Jefferies first take on $BAVA $BMY http://t.co/EGOYLeYOoO"  
[X Link](https://x.com/JacobPlieth/status/573058634499936256)  2015-03-04T09:53Z 28K followers, [--] engagements


"Cardio3 CAR-T US manufacturing plan $CARD http://t.co/87Fi458J1a"  
[X Link](https://x.com/JacobPlieth/status/581027854843920385)  2015-03-26T09:40Z 27.7K followers, [--] engagements


"Merck KGaA moves to set up a serious US presence at last $PFE http://t.co/j3iz0AltLQ http://bit.ly/1FxqEo2 http://bit.ly/1FxqEo2"  
[X Link](https://x.com/JacobPlieth/status/585418006529974272)  2015-04-07T12:25Z 27.7K followers, [--] engagements


"T-cell therapies via @EdisonHealth $JUNO $NVS $KITE $CARD $BLCM $BLUE $LBIO $CLLS $ZIOP http://t.co/i3U6W2OL7G"  
[X Link](https://x.com/JacobPlieth/status/585831092810297344)  2015-04-08T15:46Z 27.7K followers, [--] engagements


"Bernstein on Keytruda NSCLC label and PD-L1 status $MKR $BMY $RHHBY http://t.co/49afsoCIFs"  
[X Link](https://x.com/JacobPlieth/status/590084069565849600)  2015-04-20T09:26Z 27.7K followers, [--] engagements


"Leerink on Keytruda NSCLC label and PD-L1 status $MKR $BMY $RHHBY http://t.co/8suBKQcUrv"  
[X Link](https://x.com/JacobPlieth/status/590084927825272832)  2015-04-20T09:29Z 27.7K followers, [--] engagements


"TAS-102 EU approval hinges on this study presented at #ASCO15. http://t.co/hdlHh7MyS8 Licensed to Servier today $OSUKF http://meetinglibrary.asco.org/content/148025-156 http://meetinglibrary.asco.org/content/148025-156"  
[X Link](https://x.com/JacobPlieth/status/610430571790106624)  2015-06-15T12:56Z 29.9K followers, [--] engagements


"$BIIB https://x.com/JeanneWhalen/status/651398947752296448 https://x.com/JeanneWhalen/status/651398947752296448"  
[X Link](https://x.com/JacobPlieth/status/651406867982352384)  2015-10-06T14:41Z 27.7K followers, [--] engagements


"Leerink: most obvious $PFE M&A targets are $AGN $AZN $GSK & $SHPG. "Only $AGN could satisfy a full $PFE inversion.""  
[X Link](https://x.com/JacobPlieth/status/659313216342900740)  2015-10-28T10:18Z 27.7K followers, [--] engagements


"BREAKING: Afrezza maintains quarterly sales trajectory (flat at 2m) $SNY $MNKD"  
[X Link](https://x.com/JacobPlieth/status/659660925897736192)  2015-10-29T09:19Z 27.7K followers, [--] engagements


"Disturbing new trend. What exactly is a "near-term" milestone Two in two days $SNY $BMY"  
[X Link](https://x.com/JacobPlieth/status/661539195052101633)  2015-11-03T13:43Z 27.7K followers, [--] engagements


"$BIIB profiles BIIB061 the remyelination therapy that's not Lingo"  
[X Link](https://x.com/JacobPlieth/status/661559351673507844)  2015-11-03T15:03Z 27.7K followers, [--] engagements


"$SNY just gave 400m up front to Hanmi (remember the Boehringer EGFR deal) in a bid to catch up to $NVO http://en.sanofi.com/NasdaQ_OMX/local/press_releases/sanofi_and_hanmi_announce_lice_1964217_05-11-201507_00_00.aspx http://en.sanofi.com/NasdaQ_OMX/local/press_releases/sanofi_and_hanmi_announce_lice_1964217_05-11-201507_00_00.aspx"  
[X Link](https://x.com/JacobPlieth/status/662205064141004800)  2015-11-05T09:49Z 27.7K followers, [--] engagements


"$RARE CEO says Arcturus mRNA deal centres on unlocked nucleic acid tech (ie modification) & lipid encapsulation. Cf Moderna Curevac"  
[X Link](https://x.com/JacobPlieth/status/666906705507258369)  2015-11-18T09:12Z 27.7K followers, [--] engagements


"$RHHBY removals from clinical trials. RG7599 & RG7450 partnered with $SGEN"  
[X Link](https://x.com/JacobPlieth/status/692730319909326848)  2016-01-28T15:25Z 27.7K followers, [--] engagements


"5-HT6 antagonist update $AXON $PFE"  
[X Link](https://x.com/JacobPlieth/status/694520682009513985)  2016-02-02T14:00Z 27.7K followers, [--] engagements


"$SNY reports Q4 Praluent sales of 5m (vs 4m in Q3). Sellside full-year consensus was er. $47m $REGN $AMGN"  
[X Link](https://x.com/JacobPlieth/status/696998096262275072)  2016-02-09T10:04Z 27.7K followers, [--] engagements


"The Guardian does CAR-T $MLM $JUNO http://gu.com/p/4gy3z/stw http://gu.com/p/4gy3z/stw"  
[X Link](https://x.com/JacobPlieth/status/699271123700183040)  2016-02-15T16:36Z 27.7K followers, [--] engagements


"Presumably the $PTCT refuse-to-file letter is great news for $SRPT right $BMRN"  
[X Link](https://x.com/JacobPlieth/status/702123568742723585)  2016-02-23T13:31Z 27.7K followers, [--] engagements


"GDUFA $GSK $AZN $VEC $HIK"  
[X Link](https://x.com/JacobPlieth/status/718359625335246848)  2016-04-08T08:47Z 27.7K followers, [--] engagements


"Keytruda study in Merkel cell carcinoma via Paul Ngheim #AACR16 $MRK"  
[X Link](https://x.com/JacobPlieth/status/722417449413513217)  2016-04-19T13:31Z 27.7K followers, [--] engagements


"CDK inhibitors via @EPVantage; ribociclib Monaleesa-2 trial just stopped early for efficacy $NVS $PFE $LLY $BAY"  
[X Link](https://x.com/JacobPlieth/status/732842802896326656)  2016-05-18T07:58Z 27.7K followers, [--] engagements


"So a compound developed in UK by Vernalis ditched by $BIIB for Parkinson's ends up via Redox Therapies at $JUNO for oncology"  
[X Link](https://x.com/JacobPlieth/status/753692709156782080)  2016-07-14T20:48Z 27.7K followers, [--] engagements


"$AZN $BIIB $LLY $MRK $RHHBY $JNJ https://x.com/ByJonGardner/status/757523728276348929 For you #AAIC2016 watchers expecting TauRx data: https://t.co/k1rFfPas7D https://x.com/ByJonGardner/status/757523728276348929 For you #AAIC2016 watchers expecting TauRx data: https://t.co/k1rFfPas7D"  
[X Link](https://x.com/JacobPlieth/status/757524356218122241)  2016-07-25T10:34Z 27.7K followers, [--] engagements


"Quick analysis of the $PFE $AZN antibiotics purchase. Note Merrem & Zinforo numbers include US rights"  
[X Link](https://x.com/JacobPlieth/status/768365377541828608)  2016-08-24T08:32Z 27.7K followers, [--] engagements


"No affinity enhancement in $KITE engineered TCR projects (cf $ADAP )"  
[X Link](https://x.com/JacobPlieth/status/788421109372817408)  2016-10-18T16:46Z 27.7K followers, [--] engagements


"R Walter (Hutch) on bispecific competition to Blincyto $AMGN #ASH16 $JNJ"  
[X Link](https://x.com/JacobPlieth/status/804728161124683776)  2016-12-02T16:45Z 27.7K followers, [--] engagements


"Katherine High: Data on [--] haemophilia B patients given SPK-9001 $ONCE #ASH16 $QURE $PFE $SGMO $SHPG"  
[X Link](https://x.com/JacobPlieth/status/805080024500080641)  2016-12-03T16:03Z 27.7K followers, [--] engagements


"$SGEN vadastuximab (anti-CD33 ADC) phase I data in [--] 1st-line AML patients via H Erba #ASH16"  
[X Link](https://x.com/JacobPlieth/status/805145497312706560)  2016-12-03T20:23Z 27.7K followers, [--] engagements


"Cyber(in)security $DGX cc @ByMadeleineA http://ir.questdiagnostics.com/mobile.viewc=82068&v=203&d=1&id=2229113 http://ir.questdiagnostics.com/mobile.viewc=82068&v=203&d=1&id=2229113"  
[X Link](https://x.com/JacobPlieth/status/808566527704399872)  2016-12-13T06:57Z 27.7K followers, [--] engagements


"Thwarted But let's continue the $PFE rumours anyway #JPM17 https://x.com/ByMadeleineA/status/818946724366458880 @SnupSnus I think they just carried on the presentation in main room. Sorry probably a false alarm https://x.com/ByMadeleineA/status/818946724366458880 @SnupSnus I think they just carried on the presentation in main room. Sorry probably a false alarm"  
[X Link](https://x.com/JacobPlieth/status/818950151066763266)  2017-01-10T22:38Z 27.7K followers, [--] engagements


"$BMY vs $MRK since Checkmate-026 read out at #ESMO16"  
[X Link](https://x.com/JacobPlieth/status/822454097630691328)  2017-01-20T14:41Z 27.7K followers, [--] engagements


"Vas Narasimhan reckons $NVS & $AMGN have the only project targeting pre-Alzheimer's $BIIB $LLY"  
[X Link](https://x.com/JacobPlieth/status/824258945850179585)  2017-01-25T14:13Z 27.7K followers, [--] engagements


"B Boldajipour $PFE says BCMA expression is v low so had to select a v high-affinity ScFv $CLLS #ADOPT17"  
[X Link](https://x.com/JacobPlieth/status/839429757737517056)  2017-03-08T10:57Z 27.7K followers, [--] engagements


"Hearing rumour that Morgan Stanley might advise $NVO on $GBT deal. Board has authorised $NVO CEO to bid up to $45"  
[X Link](https://x.com/JacobPlieth/status/839549000600682498)  2017-03-08T18:50Z 27.7K followers, [--] engagements


"Sellside consensus revenue for ribociclib approved today as Kisqali via @evaluatepharma $NVS $PFE"  
[X Link](https://x.com/JacobPlieth/status/841614859095683072)  2017-03-14T11:39Z 27.7K followers, [--] engagements


"Bavencio trademarked by $PFE back in [----] 🤔"  
[X Link](https://x.com/JacobPlieth/status/844980541631934464)  2017-03-23T18:33Z 27.7K followers, [--] engagements


"Dr Maus now also questioning $CLLS $PFE allo CAR-T approach (UCART-EGFRvIII): rejection risk & lower effiicacy - is allo really preferable"  
[X Link](https://x.com/JacobPlieth/status/847193704326713348)  2017-03-29T21:08Z 27.7K followers, [--] engagements


"Attending #AACR17 Read my [--] preview stories with hyperlinks to key abstracts: $LLY $VLA http://bit.ly/2mjsNSR http://bit.ly/2ohpBbU http://bit.ly/2mjsNSR http://bit.ly/2ohpBbU"  
[X Link](https://x.com/JacobPlieth/status/847822767928094720)  2017-03-31T14:47Z 27.7K followers, [--] engagements


"Reminder of the various $BIIB $FWP IPR & patent interference scenarios via Umer Raffat @ ISI"  
[X Link](https://x.com/JacobPlieth/status/847841723174850560)  2017-03-31T16:03Z 27.7K followers, [--] engagements


"Bavencio (avelumab) data from Javelin Merkel [---] study via Howard Kaufman $MKGAY $PFE #AACR17"  
[X Link](https://x.com/JacobPlieth/status/848877209490251778)  2017-04-03T12:37Z 27.7K followers, [--] engagements


"Evercore ISI's Umer Raffat: this is why you have to go to #ESMO17 $BMY $AZN $MRK $RHHBY"  
[X Link](https://x.com/JacobPlieth/status/854343546899496960)  2017-04-18T14:39Z 27.7K followers, [--] engagements


"Umer Raffat: preclinical binding assays show $MRK Keytruda has highest target affinity; $AZN durvalumab lowest"  
[X Link](https://x.com/JacobPlieth/status/854347659221577730)  2017-04-18T14:55Z 27.7K followers, [--] engagements


"Basically what it's all about $AZN $MRK $BMY $RHHBY"  
[X Link](https://x.com/JacobPlieth/status/857478570804957185)  2017-04-27T06:16Z 27.7K followers, [--] engagements


"In light of Tecentriq's failure well worth rereading @ByJoFagg 's take on the bladder cancer space $RHHBY $AZN $MRK http://epvantage.com/Universal/View.aspxtype=Story&id=703083&isEPVantage=yes http://epvantage.com/Universal/View.aspxtype=Story&id=703083&isEPVantage=yes"  
[X Link](https://x.com/JacobPlieth/status/862223368375939072)  2017-05-10T08:30Z 27.7K followers, [--] engagements


".@ByJoFagg Reminder of the PD(L)1 approval landscape - table now very ungainly $MRK $BMY $AZN $RHHBY $PFE"  
[X Link](https://x.com/JacobPlieth/status/862260459373723649)  2017-05-10T10:58Z 27.7K followers, [--] engagements


"Heads up A new report on anti-PD(L)1 combination studies will be published by @EPVantage before #ASCO17 $MRK $BMY $RHHBY $AZN $PFE"  
[X Link](https://x.com/JacobPlieth/status/866014078216663042)  2017-05-20T19:33Z 27.7K followers, [--] engagements


"Phase I study of $ALPMF $SGEN anti-CD37 antibody-drug conjugate AGS67E #ICML2017"  
[X Link](https://x.com/JacobPlieth/status/875017488295186435)  2017-06-14T15:50Z 27.7K followers, [--] engagements


"$GLPG investors today on yesterday's $VRTX news"  
[X Link](https://x.com/JacobPlieth/status/887610856443392000)  2017-07-19T09:51Z 27.7K followers, [--] engagements


"Interesting though early-stage $NKTR asset picked up by $LLY. Preclinical data (& Treg mech) presented at #WCI2017 on NKTR-358 this month"  
[X Link](https://x.com/JacobPlieth/status/889448465822081024)  2017-07-24T11:33Z 27.7K followers, [--] engagements


"Ian Read waking up this morning $PFE $AZN"  
[X Link](https://x.com/JacobPlieth/status/890487193608835073)  2017-07-27T08:21Z 27.7K followers, [--] engagements


"$BMY Opdivo approval in MSI-H/MMRd limited to colorectal cancer bc that was setting of CM-142. $MRK Keytruda approval based on these trials"  
[X Link](https://x.com/JacobPlieth/status/892669241790525440)  2017-08-02T08:51Z 27.7K followers, [--] engagements


"Second AML approval in [--] days $JAZZ $AGIO $CELG $PFE $NVS https://x.com/AndyBiotech/status/893097857498193920 $JAZZ $CPXX FDA approves Vyxeos for AML https://t.co/rEgGhxUGwq https://x.com/AndyBiotech/status/893097857498193920 $JAZZ $CPXX FDA approves Vyxeos for AML https://t.co/rEgGhxUGwq"  
[X Link](https://x.com/JacobPlieth/status/893098286986534912)  2017-08-03T13:16Z 27.7K followers, [--] engagements


"With $PFE Besponsa now approved here's @ByJoFagg 's list of competing anti-CD22 projects $AZN $RHHBY $JUNO $CLLS $BAY"  
[X Link](https://x.com/JacobPlieth/status/898443009070477312)  2017-08-18T07:14Z 27.7K followers, [--] engagements


"My planned questions for next week's CAR-TCR keynote speakers $KITE $GILD"  
[X Link](https://x.com/JacobPlieth/status/902131398118658049)  2017-08-28T11:31Z 27.7K followers, [--] engagements


"As $MRK KN-183 & KN-185 go on clinical hold here are some other PD-(L)1/multiple myeloma studies worth watching. Via @ByAmyBrown $BMY $AZN"  
[X Link](https://x.com/JacobPlieth/status/903570326348591104)  2017-09-01T10:48Z 27.7K followers, [--] engagements


"L Paz-Ares presenting Imfinzi $AZN Pacific data at #ESMO17 $BMY $MRK $RHHBY"  
[X Link](https://x.com/JacobPlieth/status/906403719683735552)  2017-09-09T06:27Z 27.7K followers, [--] engagements


"Daniel Petrylak Range study of ramucirumab in urithelial $LLY #ESMO17"  
[X Link](https://x.com/JacobPlieth/status/906768364319768576)  2017-09-10T06:36Z 27.7K followers, [--] engagements


"Bernard Escudier Checkmate-214 safety & conclusions $BMY #ESMO17 $EXEL"  
[X Link](https://x.com/JacobPlieth/status/906771968627802112)  2017-09-10T06:50Z 27.7K followers, [--] engagements


"After the inevitable adcom "no" vote (& Translarna rejection) I want to see $PTCT sue the FDA $SRPT"  
[X Link](https://x.com/JacobPlieth/status/913416641152679936)  2017-09-28T14:54Z 27.7K followers, [--] engagements


"Guess what An investigator-sponsored talacotuzumab study was suspended three months ago $JNJ $XNCR"  
[X Link](https://x.com/JacobPlieth/status/920276109006180352)  2017-10-17T13:11Z 27.7K followers, [--] engagements


"So the anti-CD123 pipeline is whittled down further still $JNJ $XNCR $CLLS $NVS $STML $FBIO $SGEN $MGNX"  
[X Link](https://x.com/JacobPlieth/status/920279210740117505)  2017-10-17T13:23Z 27.7K followers, [--] engagements


"Get Carta Yescarta $KITE $GILD"  
[X Link](https://x.com/JacobPlieth/status/920887448212791296)  2017-10-19T05:40Z 27.7K followers, [--] engagements


"$KYKOF Poteligeo (mogamulizumab) beats Zolinza in CTCL patients irrespective of CCR4 expression #ASH17"  
[X Link](https://x.com/JacobPlieth/status/939843263674093573)  2017-12-10T13:04Z 29.9K followers, [--] engagements


"Note the conditions to $TKPYY 's acquisition of $TIG - EU approval of Cx601 & no material adverse events"  
[X Link](https://x.com/JacobPlieth/status/949215209016655872)  2018-01-05T09:45Z 27.7K followers, [--] engagements


"$ESRX $CVX $HUM $UNH $ANTM"  
[X Link](https://x.com/JacobPlieth/status/958329262939017216)  2018-01-30T13:21Z 27.7K followers, [--] engagements


"Spartan results via Eric Small. Apalutamide largely irrelevant given Zytiga's advancement up prostate cancer treatment cascade #GU18 $JNJ"  
[X Link](https://x.com/JacobPlieth/status/960645404089094144)  2018-02-05T22:44Z 27.7K followers, [--] engagements


"Quite the discrepancy in Immotion-151 between investigator-assessed and independently reviewed PFS $RHHBY $BMY $EXEL $PFE"  
[X Link](https://x.com/JacobPlieth/status/960877184629071875)  2018-02-06T14:05Z 27.7K followers, [--] engagements


"2018's biggest binary outcome event What to look for from the Echo-301 trial via @EPVantage $INCY http://bit.ly/2EnJCqf http://bit.ly/2EnJCqf"  
[X Link](https://x.com/JacobPlieth/status/963076420560936960)  2018-02-12T15:44Z 27.7K followers, [--] engagements


"So oncolytic viruses are back in vogue $MRK"  
[X Link](https://x.com/JacobPlieth/status/966236605873901569)  2018-02-21T09:02Z 27.7K followers, [--] engagements


"$PFE to $CLLS just now"  
[X Link](https://x.com/JacobPlieth/status/981139851247529989)  2018-04-03T12:02Z 27.7K followers, [--] engagements


"Surprise $ABLX $SNY https://x.com/bio_clouseau/status/981517553913692160 $ABLX No other interest apart from $SNY $NVO https://t.co/y2zjlymfwe https://t.co/ZLYUL9dlER https://x.com/bio_clouseau/status/981517553913692160 $ABLX No other interest apart from $SNY $NVO https://t.co/y2zjlymfwe https://t.co/ZLYUL9dlER"  
[X Link](https://x.com/JacobPlieth/status/981518317386190848)  2018-04-04T13:06Z 29.9K followers, [--] engagements


"(To the extent that it still matters) is anyone bothered by this $BMY touting TMB-high data from [---] out of a total [----] subjects enrolled into CM-227 #AACR18 $MRK"  
[X Link](https://x.com/JacobPlieth/status/985886218666864641)  2018-04-16T14:22Z 27.7K followers, [--] engagements


"$LLY $ARMO https://x.com/jacobplieth/status/978611761543831552 https://x.com/jacobplieth/status/978611761543831552"  
[X Link](https://x.com/JacobPlieth/status/994584597827604482)  2018-05-10T14:27Z 27.7K followers, [--] engagements


"$MRK KN-407: Keytruda ORR 58.4% vs 35.5% p=0.0004. Nothing on survival in abstract #ASCO18 Note $RHHBY IMP-131 is late-breaker"  
[X Link](https://x.com/JacobPlieth/status/996858074781564928)  2018-05-16T21:01Z 27.7K followers, [--] engagements


"AM0010 in NSCLC #ASCO18 $LLY smart to buy $ARMO when it did"  
[X Link](https://x.com/JacobPlieth/status/996858074848673792)  2018-05-16T21:01Z 27.7K followers, [--] engagements


"Keytruda KN-158 study in SCLC $MRK #ASCO18 Relevant for followers of upcoming $RHHBY IMP-133 & $BMY CM-451 readouts"  
[X Link](https://x.com/JacobPlieth/status/996858074961866753)  2018-05-16T21:01Z 27.7K followers, [--] engagements

Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing

@JacobPlieth Avatar @JacobPlieth Jacob Plieth

Jacob Plieth posts on X about $azn, $mrk, $pfe, $bmy the most. They currently have [------] followers and [---] posts still getting attention that total [-----] engagements in the last [--] hours.

Engagements: [-----] #

Engagements Line Chart

  • [--] Week [------] +65%
  • [--] Month [-------] -34%
  • [--] Months [---------] +35%
  • [--] Year [---------] -16%

Mentions: [--] #

Mentions Line Chart

  • [--] Week [--] +5.70%
  • [--] Month [---] -50%
  • [--] Months [---] +58%
  • [--] Year [-----] +6.90%

Followers: [------] #

Followers Line Chart

  • [--] Week [------] +0.22%
  • [--] Month [------] +0.65%
  • [--] Months [------] +4.90%
  • [--] Year [------] +12%

CreatorRank: [-------] #

CreatorRank Line Chart

Social Influence

Social category influence stocks 82.32% currencies 16.02% cryptocurrencies 14.36% finance 3.87% technology brands 2.21% countries 0.55%

Social topic influence $azn #35, $mrk #77, $pfe #196, $bmy #12, $lly #64, $jnj #53, $onc #3, $abbv #30, $nrix #4, $bdtx #13

Top accounts mentioned or mentioned by @apexonco @evaluatepharma @lionswatson @bymadeleinea @epvantage @byjofagg @charleneliao @garbageman1985 @financebully @egidiuslambrech @octopusking77 @applehelix @samfazeli8 @profoak @ablt315i @notgenentech @bioinvestor24 @raffcolo @ayishasharma97 @zacharybrennan

Top assets mentioned AstraZeneca PLC (AZN) Merck & Co., Inc. (MRK) Pfizer, Inc. (PFE) Bristol-Myers Squibb Co (BMY) Eli Lilly and Company (LLY) Johnson & Johnson (JNJ) One Cash (ONC) AbbVie Inc (ABBV) Nurix Therapeutics, Inc. (NRIX) Black Diamond Therapeutics Inc. (BDTX) Novartis AG (NVS) Terns Pharmaceuticals, Inc. (TERN) Incyte Corporation (INCY) Arcellx, Inc. (ACLX) Gilead Sciences, Inc. (GILD) Enliven Therapeutics, Inc. (ELVN) Synthetify (SNY) Seagen Inc (SGEN) Arcus Biosciences, Inc. (RCUS) GSK plc (GSK) ArriVent BioPharma, Inc. (AVBP) Instil Bio, Inc. (TIL) Novo-Nordisk (NVO) Summit Therapeutics Inc. Common Stock (SMMT) Legend Biotech Corp (LEGN) Oric Pharmaceuticals, Inc. (ORIC) Jazz Pharmaceuticals, Inc. (JAZZ) Maker (MKR) PTC Therapeutics, Inc. (PTCT) Exelixis Inc (EXEL) Allora (ALLO) CRISPR Therapeutics AG (CRSP) Caribou Biosciences, Inc. (CRBU) Abivax SA (ABVX) Kairos Pharma, Ltd. (KAPA) iTeos Therapeutics, Inc. (ITOS) Janux Therapeutics, Inc. (JANX) Sanofi (SNY) CG Oncology, Inc. (CGON) Vir Biotechnology, Inc. Common Stock (VIR) Kyverna Therapeutics, Inc. (KYTX) Axion (AXN) Moderna Inc (MRNA) Kinnate Biopharma Inc. (KNTE)

Top Social Posts

Top posts by engagements in the last [--] hours

"Is it a reverse merger Is it a fund raising I've tried to decipher the $TPST Factor deal which is structured to avoid litigation vs $CLLS & $AZN. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1740 https://www.oncologypipeline.com/apexonco/node/1740"
X Link 2025-11-20T13:49Z 31.7K followers, [----] engagements

"After $RHHBY #Tigit failed in Skyscraper-14 $RCYS $GILD terminate Star-221 for futility. Evidently someone was surprsed as $RCUS is -12% PM"
X Link 2025-12-12T13:58Z 31.7K followers, [----] engagements

"If $ABBV BTK degrader ABBV-101 has been discontinued (Evercore ISI confirms to us that it has) that's good news for $ONC & $NRIX - https://www.oncologypipeline.com/apexonco/node/1893/ https://www.oncologypipeline.com/apexonco/node/1893/"
X Link 2026-02-06T15:45Z 31.8K followers, [----] engagements

"The power of groupthink"
X Link 2026-02-11T16:28Z 31.7K followers, [----] engagements

"Quick reminder: I make that [----] patients on late-stage rilvegostomig trials $AZN $GILD $RCUS #tigit"
X Link 2025-11-06T09:00Z 31.8K followers, [----] engagements

"By my calculation $ONC now has an efficacy edge vs $NRIX in BTK degradation. Caveats: small pt numbers X-trial comparison and Nurix might have the safety advantage #ASH25"
X Link 2025-12-08T11:12Z 31.8K followers, [----] engagements

"And here's what $AZN has in store for AZD0120 via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1903 https://www.oncologypipeline.com/apexonco/node/1903"
X Link 2026-02-11T15:35Z 31.8K followers, [----] engagements

"Car-T therapy in 3rd-line DLBCL $DTIL $ACET $ALLO $CRSP $CRBU"
X Link 2024-01-05T11:46Z 31.8K followers, 18.7K engagements

"PD-1 x VEGF meet CD47 Ivonescimab +/- ligufalimab + chemo in 1L (not dMMR) colorectal. 88% ORR. China study obv. Via Yanhong Deng #ESMO24 $SMMT $BNTX"
X Link 2024-09-14T14:05Z 31.8K followers, 23.1K engagements

"@AppleHelix Surely not. $ABVX"
X Link 2026-02-12T17:47Z 31.8K followers, [----] engagements

"$KAPA reports 13mth mPFS for carotuximab + Erleada (n=8 excluding [--] patients because reasons) but somehow omits to say anything about the control arm of Erleada monotherapy. Off 17%"
X Link 2025-09-18T16:19Z 31.7K followers, [----] engagements

"I thought we were expecting $BDTX to reveal what regulatory pathway it's planning for silevertinib"
X Link 2025-12-03T12:25Z 31.7K followers, [----] engagements

"@LionsWatson .but do feel free to use this as a "buying opportunity" LOL $BDTX"
X Link 2025-12-03T14:45Z 31.7K followers, [----] engagements

"$ELVN vs $TERN: game over #ASH25"
X Link 2025-12-09T11:03Z 31.7K followers, [----] engagements

"So where does this the #tigit Fc debate Fc-active: $GSK $ITOS fail $MRK fail $RHHBY fail Fc-silent: $RCUS $GILD fail Fc-reduced: $AZN $CGEN"
X Link 2025-12-12T15:03Z 31.7K followers, [----] engagements

"Control in $INCY Frontmind (1st-line DLBCL) is R-Chop not Revlimid + R-Chop. So how do we know the (modest) PFS benefit toplined today is due to $INCY Monjuvi and not to Revlimid"
X Link 2026-01-05T14:53Z 31.7K followers, [----] engagements

"OK then let's play the "selected doses" game $ELVN $TERN"
X Link 2026-01-09T09:55Z 31.7K followers, [----] engagements

"Notable that $ELVN didn't split out the 60mg from the 120mg results. Did 60mg actually do better than 80mg All quite bizarre but stock +50% so what do I know $TERN"
X Link 2026-01-09T10:00Z 31.7K followers, [----] engagements

"Looks like $SNY discontinued Alphamedix/ SAR447873 licensed in Sep [----] from Radiomedix & Orano Med h/t B Riley. @ByMadeleineA covered it at #Esmo25 and flagged dysphagia & renal tox. Good news for $CATX https://www.oncologypipeline.com/apexonco/esmo-2025-sanofi-takes-aim-lutathera https://www.oncologypipeline.com/apexonco/esmo-2025-sanofi-takes-aim-lutathera"
X Link 2026-01-29T15:22Z 31.7K followers, [----] engagements

"With a tipoff from a friend and some info that probably shouldn't have been posted in a trial registry the mechanisms of ADCs JNJ-95437446 $JNJ & SKB571/ MK-2750 $MRK have been revealed. Quite amazing given the recent $GMAB news. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1874 https://www.oncologypipeline.com/apexonco/node/1874"
X Link 2026-01-29T15:28Z 31.7K followers, [----] engagements

"Remember MK-2750 which $MRK licensed from Kelun First revealed under the code SKB571 during #Esmo24 https://x.com/JacobPlieth/status/1838465517524320454 I just had confirmation from $MRK that MK-2750 = SKB571. Target still undisclosed. https://x.com/JacobPlieth/status/1838465517524320454 I just had confirmation from $MRK that MK-2750 = SKB571. Target still undisclosed"
X Link 2026-01-29T15:30Z 31.7K followers, [----] engagements

"MK-2750 has been in the clinic since [----]. JNJ-95437446 started phase [--] in July [----] $MRK $JNJ https://www.oncologypipeline.com/apexonco/more-conjugates-pile-clinic https://www.oncologypipeline.com/apexonco/more-conjugates-pile-clinic"
X Link 2026-01-29T15:33Z 31.7K followers, [----] engagements

"@charlene_liao @garbageman1985 $EIKN"
X Link 2026-02-03T09:24Z 31.7K followers, [---] engagements

"@charlene_liao @garbageman1985 I'm not sure there's any fund with a direct ownership link to $MRK here. $EIKN"
X Link 2026-02-03T09:29Z 31.7K followers, [---] engagements

"Interesting difference: the corresponding US approval has no restriction to dMMR (remember PFS HR=0.60 in pMMR but [----] in dMMR) $MRK $MRK announced that its PD-1 inhibitor pembrolizumab (Keytruda) has been approved by NMPA for 1L treatment of adult patients with dMMR primary advanced or recurrent endometrial cancer in combination with carboplatin and paclitaxel followed by maintenance therapy with $MRK announced that its PD-1 inhibitor pembrolizumab (Keytruda) has been approved by NMPA for 1L treatment of adult patients with dMMR primary advanced or recurrent endometrial cancer in"
X Link 2026-02-06T10:27Z 31.7K followers, [----] engagements

"@SamFazeli8 15% below the issue price and 55% below the average at which VCs invested. I think the IPO window does indeed remain putative $EIKN"
X Link 2026-02-06T15:02Z 31.7K followers, [----] engagements

"@Prof_Oak_ I'd be surprised if the up-front was more than $100m $LLY"
X Link 2026-02-09T16:10Z 31.7K followers, [---] engagements

"Ascentage just disclosed that it's developing a BTK degrader: APG-3288 apparently just had its US IND cleared $ONC $NRIX"
X Link 2026-01-09T14:53Z 31.8K followers, [----] engagements

"So $LLY not interested in oncology applications of Orna's in vivo Car-T $ABBV $AZN $BMY $GILD"
X Link 2026-02-09T12:27Z 31.7K followers, 11.3K engagements

"Important similarity between $LLY Orna's and $BMY Orbital's approaches to in vivo Car-T"
X Link 2026-02-09T13:52Z 31.7K followers, [----] engagements

"Key late-breakers at Asco #GU26 include Litespark-011 & [---] Keynote-B15. and who's heard of Flare Therapeutics Via @ApexOnco - $MRK $PFE $ALMPF $CGON $VIR https://www.oncologypipeline.com/apexonco/node/1908 https://www.oncologypipeline.com/apexonco/node/1908"
X Link 2026-02-12T12:58Z 31.7K followers, [----] engagements

"New in vivo Car-T player NCI licensing patent for an anti-CD19 in vivo Car-T for autoimmune disease to $KYTX - https://public-inspection.federalregister.gov/2026-02907.pdf https://public-inspection.federalregister.gov/2026-02907.pdf"
X Link 2026-02-12T13:56Z 31.7K followers, [----] engagements

"$SNY deserves congratulations for finding a new CEO whose track record makes Paul Hudson look good. Chapeau"
X Link 2026-02-12T14:30Z 31.7K followers, [----] engagements

"$LEGN quietly making a big push into in vivo Car-T: LVIVO-TaVec100 (CD19 x CD20) LVIVO-TaVec200 (GPRC5D) LVIVO-TaVec400 (target undisclosed) .all recently entered human trials"
X Link 2026-02-12T20:28Z 31.7K followers, [----] engagements

"At last $MRK nemtabrutinib (non-cov BTKi via $ARQL) makes progress in ph3. Third pivotal study head-to-head vs Imbruvica or Calquence (but not Brukinsa) just listed on CTgov $LLY $BGNE https://classic.clinicaltrials.gov/ct2/show/NCT06136559 https://classic.clinicaltrials.gov/ct2/show/NCT06136559"
X Link 2023-11-20T11:15Z 31.7K followers, [----] engagements

"$BGNE -10% $NRIX +8%. I'm puzzled. #ASH24 data: https://x.com/JacobPlieth/status/1866262593217921411 https://x.com/JacobPlieth/status/1866258468157677750 And here's $BGNE's BTK degrader BGB-16673 in CLL. 93% post cov BTK 22% post non-cov BTK. 78% ORR (94% ORR at 200mg) [--] (unrelated) deaths. Via Meghan Thompson #ASH24 $NRIX https://t.co/sWnrnMJ4S4 https://x.com/JacobPlieth/status/1866262593217921411 https://x.com/JacobPlieth/status/1866258468157677750 And here's $BGNE's BTK degrader BGB-16673 in CLL. 93% post cov BTK 22% post non-cov BTK. 78% ORR (94% ORR at 200mg) [--] (unrelated) deaths. Via"
X Link 2024-12-10T15:50Z 31.7K followers, 19K engagements

"$DSNKY DS3610 starting phase [--] in October. Sting agonist payload ADC (targets still unknown - any ideas) https://clinicaltrials.gov/study/NCT07159126 https://clinicaltrials.gov/study/NCT07159126"
X Link 2025-09-15T08:37Z 31.8K followers, [----] engagements

"First $AFMD now $IPHA. what say $ONC & any others still involved in NK-cell engagers Hopes dim for $IPHA NK-cell engagers https://t.co/81ywllXRUS Hopes dim for $IPHA NK-cell engagers https://t.co/81ywllXRUS"
X Link 2025-09-17T13:16Z 31.7K followers, [----] engagements

"3 new patients zero new responses. Quick take on $ORIC via @Apexonco - https://www.oncologypipeline.com/apexonco/node/1728 https://www.oncologypipeline.com/apexonco/node/1728"
X Link 2025-11-14T15:58Z 31.8K followers, [----] engagements

".or is this the regulatory update: no accelerated pathway needs pivotal trial and $BDTX can't run this without a partner"
X Link 2025-12-03T12:28Z 31.8K followers, [----] engagements

"Silevertinib in 1L NSCLC non-classical mutations. Data look decent but $BDTX needs a partner to fund pivotal development"
X Link 2025-12-03T13:12Z 31.8K followers, [----] engagements

"$BDTX currently off 17% (earlier -30%) on yet another strategic pivot. @ApexOnco take on today's silevertinib data $AVBP https://www.oncologypipeline.com/apexonco/node/1767 https://www.oncologypipeline.com/apexonco/node/1767"
X Link 2025-12-03T16:22Z 31.7K followers, [----] engagements

"Beautifully buried discontinuation of acasunlimab by $GMAB yesterday. A disaster that's been a long time coming and remember GMAB went into phase [--] on its own despite $BNTX earlier pulling the plug https://www.oncologypipeline.com/apexonco/another-vote-no-confidence-co-stimulated-bispecifics https://www.oncologypipeline.com/apexonco/another-vote-no-confidence-co-stimulated-bispecifics"
X Link 2025-12-30T19:51Z 31.7K followers, [----] engagements

"That's confirmed now - #GI26 late-breaking abstract LBA285 $JAZZ $ONC $ZYME $JAZZ Ziihera data from Herizon-GEA-01 study coming at #GI26 https://t.co/WkJdU7lmX7 $JAZZ Ziihera data from Herizon-GEA-01 study coming at #GI26 https://t.co/WkJdU7lmX7"
X Link 2026-01-02T16:08Z 31.8K followers, [----] engagements

"How many people had $TIL scrapping the Immuneonco deal discontinuing PD-1 x VEGF and going back to TIL therapeutics on their #JPM26 bingo card"
X Link 2026-01-06T13:24Z 31.7K followers, 11.3K engagements

"And here's Immuneonco's statement on the $TIL discontinuation. Still says nothing about the reason(s) https://x.com/chuminhua432/status/2008835430263984618 ImmuneOnco announced that Axion Bio Inc. a wholly-owned subsidiary of $TIL has decided to discontinue clinical development of IMM2510/AXN-2510. https://t.co/iWwc7oAa8N Axion and ImmuneOnco have entered into an agreement terminating their license and collaboration https://x.com/chuminhua432/status/2008835430263984618 ImmuneOnco announced that Axion Bio Inc. a wholly-owned subsidiary of $TIL has decided to discontinue clinical development of"
X Link 2026-01-07T09:47Z 31.7K followers, [----] engagements

"$EIKN share price averaged over private financings vs at expected IPO. Normally there's a (substantial) step up when companies float. Not in this case"
X Link 2026-02-02T15:27Z 31.7K followers, 12.7K engagements

"$MRK confirming that Interpath-001 study of $MRNA partnered intismeran autogene is "ongoing & fully enrolled". No further guidance as to timing of results due some time in [----]. My earlier take on what to expect: https://www.oncologypipeline.com/apexonco/moderna-investors-prepare-phase-3-reveal https://www.oncologypipeline.com/apexonco/moderna-investors-prepare-phase-3-reveal"
X Link 2026-02-04T09:48Z 31.7K followers, [----] engagements

"Six years after buying Arqule $MRK is talking about nemtabrutinib again. [----] launch possibility $LLY"
X Link 2026-02-04T09:51Z 31.7K followers, [----] engagements

"$DSNKY's first DXd ADC for haematology DS-3790 enters the clinic. As I reported last November: https://www.oncologypipeline.com/apexonco/sutro-goes-back-work https://www.oncologypipeline.com/apexonco/sutro-goes-back-work"
X Link 2026-02-04T12:04Z 31.8K followers, [----] engagements

"$EIKN prices at $18/share to raise $381m at a $972m market cap. Here's @ApexOnco on what this IPO tells us: https://www.oncologypipeline.com/apexonco/node/1891 https://www.oncologypipeline.com/apexonco/node/1891"
X Link 2026-02-05T12:44Z 31.7K followers, [----] engagements

"Who knew that $MRK filing for KN-B96 indication had [--] separate Pdufa dates one for IV and one for SC Keytruda Remember Keytruda Qlex was approved for "most" solid tumour IV indications. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1905 https://www.oncologypipeline.com/apexonco/node/1905"
X Link 2026-02-11T15:39Z 31.8K followers, [----] engagements

"That's from an industry newsletter that just landed in my inbox. Biopharma's R&D crisis summarised in a single quote"
X Link 2026-02-11T16:41Z 31.7K followers, [----] engagements

"$ABBV believes in the world according to GARP and takes livmoniplimab into phase [--] - on zero monoRx activity and lacklustre budigalimab combo data. What can possibly go wrong Via @ApexOnco - https://www.oncologypipeline.com/apexonco/abbvie-sees-world-according-garp https://www.oncologypipeline.com/apexonco/abbvie-sees-world-according-garp"
X Link 2024-02-05T16:24Z 31.8K followers, [----] engagements

"Free money for $XOMA Buys $KNTE for $110m in cash gets cash balance ($180m in Q3 [----] minimum $120m at close) plus a CVR punt on exarafenib https://investors.kinnate.com/news-releases/news-release-details/kinnate-biopharma-inc-enters-agreement-be-acquired-xoma https://investors.kinnate.com/news-releases/news-release-details/kinnate-biopharma-inc-enters-agreement-be-acquired-xoma"
X Link 2024-02-16T13:20Z 31.8K followers, [----] engagements

"$GMAB looked at $STRO but decided instead to pay 5x more for Profoundbio. My take on the $1.8bn acquisition via @ApexOnco - https://www.oncologypipeline.com/apexonco/profoundbio-takeout-shines-light-sutro https://www.oncologypipeline.com/apexonco/profoundbio-takeout-shines-light-sutro"
X Link 2024-04-03T13:46Z 31.7K followers, 33.5K engagements

"$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24"
X Link 2024-12-10T23:46Z 31.7K followers, [----] engagements

"Something tells me $GMAB is about to get eclipsed in folate receptor alpha ADC $LLY $AZN #ESMO25"
X Link 2025-10-19T12:42Z 31.8K followers, [----] engagements

"If you need some biotech reading over Thanksgiving check out @ApexOnco previews of #ASH25 -- Starts in just over a week $ACLX $ONC $CRVS $TERN $KURA $SNDX $CGEM $INCY https://www.oncologypipeline.com/apexonco/search/nodekeys=%22ash+2025%22 https://www.oncologypipeline.com/apexonco/search/nodekeys=%22ash+2025%22"
X Link 2025-11-27T13:37Z 31.8K followers, [----] engagements

"@LionsWatson I'm so sorry for being insufficiently enthusiastic with my praise for $BDTX. Anyway here's $AVBP"
X Link 2025-12-03T14:02Z 31.7K followers, [----] engagements

"$NRIX +23% surprises me. I thought the #ASH25 data showed $ONC to be better on efficacy (with caveats) albeit worse on safety. My earlier take on @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1775 https://www.oncologypipeline.com/apexonco/node/1775"
X Link 2025-12-08T15:41Z 31.7K followers, [----] engagements

"$LLY Jaypirca looks best. up to a point. Via @ApexOnco from #ASH25 $ONC $AZN $JNJ $ABBV $NRIX https://www.oncologypipeline.com/apexonco/node/1772/ https://www.oncologypipeline.com/apexonco/node/1772/"
X Link 2025-12-09T12:45Z 31.8K followers, [----] engagements

"@ablT315I And. here come the sellside notes defending $ACLX"
X Link 2025-12-09T17:14Z 31.8K followers, [---] engagements

"What a stinker of an #ASH25 for $ACLX -16% since Nov abstract drop. Inconsequential Immagine-1 update while others making huge strides"
X Link 2025-12-09T17:30Z 31.8K followers, [----] engagements

"Interesting flurry of activity in LRRC15: $IPN.PA today licensed Simcere's SIM0613 (ADC). $LNTH prepares to take LNTH-2403 (Lu-177 radioTx) into phase [--]. In Jan $ZLAB did deal with Medilink to develop ZL-6201 as an ADC. $ABBV earlier abandoned ph1 samrotamab vedotin"
X Link 2025-12-22T09:31Z 31.8K followers, [----] engagements

"@NotGenentech @bioinvestor24 Here's a list of just the clinical pan-RAS & pan-KRAS assets from Oncologypipeline $RVMD $LLY $ONC $RHHBY $PFE $ERAS $AZN $AMGN $ALPMF"
X Link 2025-12-22T12:09Z 31.7K followers, [---] engagements

"Still not convinced by $ELVN Via @ApexOnco - $TERN https://www.oncologypipeline.com/apexonco/node/1826 https://www.oncologypipeline.com/apexonco/node/1826"
X Link 2026-01-09T15:01Z 31.7K followers, [----] engagements

"Seven days after $TIL pulled the plug Immuneonco says it's still independently developing its PD-L1 x VEGF trap palverafusp alfa $SMMT $BNTX https://mp.weixin.qq.com/s/8mykgEpQrSLXUhDuLa1AJg https://mp.weixin.qq.com/s/8mykgEpQrSLXUhDuLa1AJg"
X Link 2026-01-14T12:00Z 31.7K followers, [----] engagements

"All good still for $ACLX though Carvykti is now a blockbuster with FY [----] sales of 1.9bn from $963m in FY [----] $JNJ Carvykti is now a blockbuster with FY [----] sales of 1.9bn from $963m in FY [----] $JNJ"
X Link 2026-01-21T13:22Z 31.7K followers, [----] engagements

"Several scoops among the latest ADC names. Via @ApexOnco with H/T to @raffcolo - https://www.oncologypipeline.com/apexonco/node/1883/ https://www.oncologypipeline.com/apexonco/node/1883/"
X Link 2026-02-04T10:30Z 31.7K followers, [----] engagements

"Some revelations for ADC nerds: $SNY uses the same MAb in its new CEACAM5 ADC as in the one it discontinued in [----]. Chia Tai claims a deuterated DXd payload (with no link to $DSNKY). $DSNKY TA-MUC1 ADC uses sacomitatug not Glycotope's gatipotuzumab"
X Link 2026-02-04T10:35Z 31.7K followers, [----] engagements

"Confirmned discontinuation of $NVS PIT565 which seems to be a specifically targeted T-cell engager (also hit CD2). cf $AZN Titan platform. There are several projects missing from the $NVS phase [--] pipeline in Q4 (left) vs Q3 (right) plus a couple of new projects https://t.co/NuTJbS8T0p There are several projects missing from the $NVS phase [--] pipeline in Q4 (left) vs Q3 (right) plus a couple of new projects https://t.co/NuTJbS8T0p"
X Link 2026-02-04T12:48Z 31.7K followers, [----] engagements

"What could possibly have gone wrong indeed Looks like $ABBV has all but discontinued the anti-GARP MAb livmoniplimab. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1893/ https://www.oncologypipeline.com/apexonco/node/1893/"
X Link 2026-02-06T15:42Z 31.7K followers, [----] engagements

"Interesting disclosure from $ABBV Q4 presentation: ABBV-901 is an anti-FR ADC - so trying to improve on Elahere given the threats of $GMAB $LLY etc https://clinicaltrials.gov/study/NCT07278336 https://clinicaltrials.gov/study/NCT07278336"
X Link 2026-02-09T09:48Z 31.8K followers, [----] engagements

"Now $ORIC goes after $AVBP & $BDTX in 1st-line PACC lung cancer and shows why it abandoned relapsed HER2 ex20. Via @ApexOnco - https://www.oncologypipeline.com/apexonco/node/1771/ https://www.oncologypipeline.com/apexonco/node/1771/"
X Link 2025-12-05T13:58Z 31.8K followers, [----] engagements

"The enlarged $TPST prioritising a CD19 x BCMA Car-T (TPST-2003) just as $AZN launches its phase [--] study of (ex $GRCL) AZD0120/GC012F: https://clinicaltrials.gov/study/NCT07391657 https://clinicaltrials.gov/study/NCT07391657"
X Link 2026-02-11T12:32Z 31.8K followers, [----] engagements

"Wow check out the $JNJ Tecvayli survival curves in Majestec-3 #ASH25"
X Link 2025-12-09T13:02Z 31.8K followers, [----] engagements

"$JNJ Tecvayli (& $LEGN Carvykti) "entering a new era of resetting survival expectations in a cancer historically described as incurable". @ByMadeleineA @ApexOnco from #ASH25 on Majestec-3 $ACLX $BMY https://www.oncologypipeline.com/apexonco/node/1782 https://www.oncologypipeline.com/apexonco/node/1782"
X Link 2025-12-09T13:05Z 31.8K followers, [----] engagements

"You see @Ayisha_Sharma97 this is how common professional courtesy works. Learn from your colleague @ZacharyBrennan"
X Link 2026-02-11T21:37Z 31.7K followers, 10.2K engagements

"$AZN isn't the only company that still believes in PD-(L)1 x TIGIT: SH006 just went into phase [--] https://clinicaltrials.gov/study/NCT07392866 https://clinicaltrials.gov/study/NCT07392866"
X Link 2026-02-12T20:50Z 31.7K followers, [----] engagements

"Positive for $HNSN $SYK $MAKO $ISRG http://t.co/rrQAMVBfFQ http://phx.corporate-ir.net/phoenix.zhtmlc=118965&p=irol-newsArticle&ID=1857846&highlight= http://phx.corporate-ir.net/phoenix.zhtmlc=118965&p=irol-newsArticle&ID=1857846&highlight="
X Link 2013-09-25T12:20Z 27.7K followers, [--] engagements

"While $OREX stock has slumped consensus forecasts for [----] Contrave sales have surged in the past [--] months http://t.co/DKWTlPvGMn"
X Link 2013-11-25T10:18Z 27.7K followers, [--] engagements

"Gotlib on relative characteristics of JAK inhibitors $GILD $INCY http://t.co/BSFDHpl5zi"
X Link 2013-12-07T21:43Z 27.7K followers, [--] engagements

"How palbociclib's consensus sales forecasts have come up. $AMGN battle for Onyx started in July. $PFE http://t.co/TeE7KolgfO"
X Link 2014-02-03T12:17Z 27.7K followers, [--] engagements

"So with $QCOR it's price gouging but with $RTRX it's a smart move understanding the market and providing value. Brilliant"
X Link 2014-02-13T14:05Z 27.7K followers, [--] engagements

"Yes folks $BMY has just been asked whether it will be able to compete with $AZN $PFE in immu-onc"
X Link 2014-04-29T14:01Z 27.7K followers, [--] engagements

"Bernstein on UK market share of Siemens' hearing aid biz now set for spin-out $SI http://t.co/BEZtwiRWND"
X Link 2014-05-07T08:25Z 27.7K followers, [--] engagements

"US VA hearing aid market via Bernstein $SI $SOON $WDH http://t.co/T9wrcVBVaj"
X Link 2014-05-07T08:27Z 27.7K followers, [--] engagements

"$LUN not disclosing specific trigger for $CHTP CVRs beyond saying it concerns Northera sales exceeding a base case http://t.co/z0qE07mu9K"
X Link 2014-05-08T12:12Z 27.7K followers, [--] engagements

"Good take on $AZN $PFE by @PanmureSavvas http://t.co/wmAS9Mir2u"
X Link 2014-05-14T08:17Z 27.7K followers, [--] engagements

"Well played Bryan Garnier $AZN $PFE http://t.co/40Sg8y7d7M"
X Link 2014-05-14T08:19Z 27.7K followers, [--] engagements

"$AZN #BTD AZD9291 efficacy in phase I T790M+ NSCLC $CLVS $PFE #ASCO14 http://t.co/wNYWJjZESD"
X Link 2014-05-14T21:20Z 27.7K followers, [--] engagements

"Thrombogenics burns through EUR15.5m in three months. Strategic review still ongoing. $THR"
X Link 2014-05-22T16:12Z 27.7K followers, [--] engagements

"$ATLN CEO says he was expecting any more patients to discontinue in Griphon given the length of the trial $UTHR"
X Link 2014-06-16T12:06Z 27.7K followers, [--] engagements

"$PFE's $ALCLS deal makes Servier (and Orbimed Ridgeback Aquilo VenBio & Merlin Nexus) look super smart"
X Link 2014-06-18T11:45Z 27.7K followers, [--] engagements

"Leerink's take on Keytruda off-label use $MRK $BMY #PD1 http://t.co/MkwsptgBcq"
X Link 2014-09-05T09:54Z 27.7K followers, [--] engagements

"Fact: [--] months ago odanacatib was $MRK's most valuable R&D asset. How [----] forecast has fallen via @evaluatepharma http://t.co/EwohQUD1V4"
X Link 2014-09-15T08:14Z 27.7K followers, [--] engagements

"UBS sees an optimistic read-across to $INCY of the $RHHBY $NLNK IDO deal. http://t.co/P7VanZby4B"
X Link 2014-10-20T14:09Z 27.7K followers, [--] engagements

"Prolor (bought by $OPK) was an Israeli company. The $295m non-up-front up-front could be $PFE using up offshore cash"
X Link 2014-12-15T13:23Z 27.7K followers, [--] engagements

"UBS on Kalydeco's R117H approval and beyond $VRTX http://t.co/EDedjHIeyo"
X Link 2014-12-30T12:47Z 27.7K followers, [--] engagements

"I just spoke to the $CARD CEO. Lead CAR construct (with NKG2D) uses CD3zeta plus DAP10 as a natural co-stim domain http://t.co/ExK8uM2NP6"
X Link 2015-01-06T15:55Z 27.7K followers, [--] engagements

"$AZN late-stage oncology highlights http://t.co/avYeGhIrwJ"
X Link 2015-02-05T09:25Z 27.7K followers, [--] engagements

"Still a potential big pharma partner is probably better than none and that's what $BAVA has today. $BMY"
X Link 2015-03-04T08:39Z 28K followers, [--] engagements

"Jefferies first take on $BAVA $BMY http://t.co/EGOYLeYOoO"
X Link 2015-03-04T09:53Z 28K followers, [--] engagements

"Cardio3 CAR-T US manufacturing plan $CARD http://t.co/87Fi458J1a"
X Link 2015-03-26T09:40Z 27.7K followers, [--] engagements

"Merck KGaA moves to set up a serious US presence at last $PFE http://t.co/j3iz0AltLQ http://bit.ly/1FxqEo2 http://bit.ly/1FxqEo2"
X Link 2015-04-07T12:25Z 27.7K followers, [--] engagements

"T-cell therapies via @EdisonHealth $JUNO $NVS $KITE $CARD $BLCM $BLUE $LBIO $CLLS $ZIOP http://t.co/i3U6W2OL7G"
X Link 2015-04-08T15:46Z 27.7K followers, [--] engagements

"Bernstein on Keytruda NSCLC label and PD-L1 status $MKR $BMY $RHHBY http://t.co/49afsoCIFs"
X Link 2015-04-20T09:26Z 27.7K followers, [--] engagements

"Leerink on Keytruda NSCLC label and PD-L1 status $MKR $BMY $RHHBY http://t.co/8suBKQcUrv"
X Link 2015-04-20T09:29Z 27.7K followers, [--] engagements

"TAS-102 EU approval hinges on this study presented at #ASCO15. http://t.co/hdlHh7MyS8 Licensed to Servier today $OSUKF http://meetinglibrary.asco.org/content/148025-156 http://meetinglibrary.asco.org/content/148025-156"
X Link 2015-06-15T12:56Z 29.9K followers, [--] engagements

"$BIIB https://x.com/JeanneWhalen/status/651398947752296448 https://x.com/JeanneWhalen/status/651398947752296448"
X Link 2015-10-06T14:41Z 27.7K followers, [--] engagements

"Leerink: most obvious $PFE M&A targets are $AGN $AZN $GSK & $SHPG. "Only $AGN could satisfy a full $PFE inversion.""
X Link 2015-10-28T10:18Z 27.7K followers, [--] engagements

"BREAKING: Afrezza maintains quarterly sales trajectory (flat at 2m) $SNY $MNKD"
X Link 2015-10-29T09:19Z 27.7K followers, [--] engagements

"Disturbing new trend. What exactly is a "near-term" milestone Two in two days $SNY $BMY"
X Link 2015-11-03T13:43Z 27.7K followers, [--] engagements

"$BIIB profiles BIIB061 the remyelination therapy that's not Lingo"
X Link 2015-11-03T15:03Z 27.7K followers, [--] engagements

"$SNY just gave 400m up front to Hanmi (remember the Boehringer EGFR deal) in a bid to catch up to $NVO http://en.sanofi.com/NasdaQ_OMX/local/press_releases/sanofi_and_hanmi_announce_lice_1964217_05-11-201507_00_00.aspx http://en.sanofi.com/NasdaQ_OMX/local/press_releases/sanofi_and_hanmi_announce_lice_1964217_05-11-201507_00_00.aspx"
X Link 2015-11-05T09:49Z 27.7K followers, [--] engagements

"$RARE CEO says Arcturus mRNA deal centres on unlocked nucleic acid tech (ie modification) & lipid encapsulation. Cf Moderna Curevac"
X Link 2015-11-18T09:12Z 27.7K followers, [--] engagements

"$RHHBY removals from clinical trials. RG7599 & RG7450 partnered with $SGEN"
X Link 2016-01-28T15:25Z 27.7K followers, [--] engagements

"5-HT6 antagonist update $AXON $PFE"
X Link 2016-02-02T14:00Z 27.7K followers, [--] engagements

"$SNY reports Q4 Praluent sales of 5m (vs 4m in Q3). Sellside full-year consensus was er. $47m $REGN $AMGN"
X Link 2016-02-09T10:04Z 27.7K followers, [--] engagements

"The Guardian does CAR-T $MLM $JUNO http://gu.com/p/4gy3z/stw http://gu.com/p/4gy3z/stw"
X Link 2016-02-15T16:36Z 27.7K followers, [--] engagements

"Presumably the $PTCT refuse-to-file letter is great news for $SRPT right $BMRN"
X Link 2016-02-23T13:31Z 27.7K followers, [--] engagements

"GDUFA $GSK $AZN $VEC $HIK"
X Link 2016-04-08T08:47Z 27.7K followers, [--] engagements

"Keytruda study in Merkel cell carcinoma via Paul Ngheim #AACR16 $MRK"
X Link 2016-04-19T13:31Z 27.7K followers, [--] engagements

"CDK inhibitors via @EPVantage; ribociclib Monaleesa-2 trial just stopped early for efficacy $NVS $PFE $LLY $BAY"
X Link 2016-05-18T07:58Z 27.7K followers, [--] engagements

"So a compound developed in UK by Vernalis ditched by $BIIB for Parkinson's ends up via Redox Therapies at $JUNO for oncology"
X Link 2016-07-14T20:48Z 27.7K followers, [--] engagements

"$AZN $BIIB $LLY $MRK $RHHBY $JNJ https://x.com/ByJonGardner/status/757523728276348929 For you #AAIC2016 watchers expecting TauRx data: https://t.co/k1rFfPas7D https://x.com/ByJonGardner/status/757523728276348929 For you #AAIC2016 watchers expecting TauRx data: https://t.co/k1rFfPas7D"
X Link 2016-07-25T10:34Z 27.7K followers, [--] engagements

"Quick analysis of the $PFE $AZN antibiotics purchase. Note Merrem & Zinforo numbers include US rights"
X Link 2016-08-24T08:32Z 27.7K followers, [--] engagements

"No affinity enhancement in $KITE engineered TCR projects (cf $ADAP )"
X Link 2016-10-18T16:46Z 27.7K followers, [--] engagements

"R Walter (Hutch) on bispecific competition to Blincyto $AMGN #ASH16 $JNJ"
X Link 2016-12-02T16:45Z 27.7K followers, [--] engagements

"Katherine High: Data on [--] haemophilia B patients given SPK-9001 $ONCE #ASH16 $QURE $PFE $SGMO $SHPG"
X Link 2016-12-03T16:03Z 27.7K followers, [--] engagements

"$SGEN vadastuximab (anti-CD33 ADC) phase I data in [--] 1st-line AML patients via H Erba #ASH16"
X Link 2016-12-03T20:23Z 27.7K followers, [--] engagements

"Cyber(in)security $DGX cc @ByMadeleineA http://ir.questdiagnostics.com/mobile.viewc=82068&v=203&d=1&id=2229113 http://ir.questdiagnostics.com/mobile.viewc=82068&v=203&d=1&id=2229113"
X Link 2016-12-13T06:57Z 27.7K followers, [--] engagements

"Thwarted But let's continue the $PFE rumours anyway #JPM17 https://x.com/ByMadeleineA/status/818946724366458880 @SnupSnus I think they just carried on the presentation in main room. Sorry probably a false alarm https://x.com/ByMadeleineA/status/818946724366458880 @SnupSnus I think they just carried on the presentation in main room. Sorry probably a false alarm"
X Link 2017-01-10T22:38Z 27.7K followers, [--] engagements

"$BMY vs $MRK since Checkmate-026 read out at #ESMO16"
X Link 2017-01-20T14:41Z 27.7K followers, [--] engagements

"Vas Narasimhan reckons $NVS & $AMGN have the only project targeting pre-Alzheimer's $BIIB $LLY"
X Link 2017-01-25T14:13Z 27.7K followers, [--] engagements

"B Boldajipour $PFE says BCMA expression is v low so had to select a v high-affinity ScFv $CLLS #ADOPT17"
X Link 2017-03-08T10:57Z 27.7K followers, [--] engagements

"Hearing rumour that Morgan Stanley might advise $NVO on $GBT deal. Board has authorised $NVO CEO to bid up to $45"
X Link 2017-03-08T18:50Z 27.7K followers, [--] engagements

"Sellside consensus revenue for ribociclib approved today as Kisqali via @evaluatepharma $NVS $PFE"
X Link 2017-03-14T11:39Z 27.7K followers, [--] engagements

"Bavencio trademarked by $PFE back in [----] 🤔"
X Link 2017-03-23T18:33Z 27.7K followers, [--] engagements

"Dr Maus now also questioning $CLLS $PFE allo CAR-T approach (UCART-EGFRvIII): rejection risk & lower effiicacy - is allo really preferable"
X Link 2017-03-29T21:08Z 27.7K followers, [--] engagements

"Attending #AACR17 Read my [--] preview stories with hyperlinks to key abstracts: $LLY $VLA http://bit.ly/2mjsNSR http://bit.ly/2ohpBbU http://bit.ly/2mjsNSR http://bit.ly/2ohpBbU"
X Link 2017-03-31T14:47Z 27.7K followers, [--] engagements

"Reminder of the various $BIIB $FWP IPR & patent interference scenarios via Umer Raffat @ ISI"
X Link 2017-03-31T16:03Z 27.7K followers, [--] engagements

"Bavencio (avelumab) data from Javelin Merkel [---] study via Howard Kaufman $MKGAY $PFE #AACR17"
X Link 2017-04-03T12:37Z 27.7K followers, [--] engagements

"Evercore ISI's Umer Raffat: this is why you have to go to #ESMO17 $BMY $AZN $MRK $RHHBY"
X Link 2017-04-18T14:39Z 27.7K followers, [--] engagements

"Umer Raffat: preclinical binding assays show $MRK Keytruda has highest target affinity; $AZN durvalumab lowest"
X Link 2017-04-18T14:55Z 27.7K followers, [--] engagements

"Basically what it's all about $AZN $MRK $BMY $RHHBY"
X Link 2017-04-27T06:16Z 27.7K followers, [--] engagements

"In light of Tecentriq's failure well worth rereading @ByJoFagg 's take on the bladder cancer space $RHHBY $AZN $MRK http://epvantage.com/Universal/View.aspxtype=Story&id=703083&isEPVantage=yes http://epvantage.com/Universal/View.aspxtype=Story&id=703083&isEPVantage=yes"
X Link 2017-05-10T08:30Z 27.7K followers, [--] engagements

".@ByJoFagg Reminder of the PD(L)1 approval landscape - table now very ungainly $MRK $BMY $AZN $RHHBY $PFE"
X Link 2017-05-10T10:58Z 27.7K followers, [--] engagements

"Heads up A new report on anti-PD(L)1 combination studies will be published by @EPVantage before #ASCO17 $MRK $BMY $RHHBY $AZN $PFE"
X Link 2017-05-20T19:33Z 27.7K followers, [--] engagements

"Phase I study of $ALPMF $SGEN anti-CD37 antibody-drug conjugate AGS67E #ICML2017"
X Link 2017-06-14T15:50Z 27.7K followers, [--] engagements

"$GLPG investors today on yesterday's $VRTX news"
X Link 2017-07-19T09:51Z 27.7K followers, [--] engagements

"Interesting though early-stage $NKTR asset picked up by $LLY. Preclinical data (& Treg mech) presented at #WCI2017 on NKTR-358 this month"
X Link 2017-07-24T11:33Z 27.7K followers, [--] engagements

"Ian Read waking up this morning $PFE $AZN"
X Link 2017-07-27T08:21Z 27.7K followers, [--] engagements

"$BMY Opdivo approval in MSI-H/MMRd limited to colorectal cancer bc that was setting of CM-142. $MRK Keytruda approval based on these trials"
X Link 2017-08-02T08:51Z 27.7K followers, [--] engagements

"Second AML approval in [--] days $JAZZ $AGIO $CELG $PFE $NVS https://x.com/AndyBiotech/status/893097857498193920 $JAZZ $CPXX FDA approves Vyxeos for AML https://t.co/rEgGhxUGwq https://x.com/AndyBiotech/status/893097857498193920 $JAZZ $CPXX FDA approves Vyxeos for AML https://t.co/rEgGhxUGwq"
X Link 2017-08-03T13:16Z 27.7K followers, [--] engagements

"With $PFE Besponsa now approved here's @ByJoFagg 's list of competing anti-CD22 projects $AZN $RHHBY $JUNO $CLLS $BAY"
X Link 2017-08-18T07:14Z 27.7K followers, [--] engagements

"My planned questions for next week's CAR-TCR keynote speakers $KITE $GILD"
X Link 2017-08-28T11:31Z 27.7K followers, [--] engagements

"As $MRK KN-183 & KN-185 go on clinical hold here are some other PD-(L)1/multiple myeloma studies worth watching. Via @ByAmyBrown $BMY $AZN"
X Link 2017-09-01T10:48Z 27.7K followers, [--] engagements

"L Paz-Ares presenting Imfinzi $AZN Pacific data at #ESMO17 $BMY $MRK $RHHBY"
X Link 2017-09-09T06:27Z 27.7K followers, [--] engagements

"Daniel Petrylak Range study of ramucirumab in urithelial $LLY #ESMO17"
X Link 2017-09-10T06:36Z 27.7K followers, [--] engagements

"Bernard Escudier Checkmate-214 safety & conclusions $BMY #ESMO17 $EXEL"
X Link 2017-09-10T06:50Z 27.7K followers, [--] engagements

"After the inevitable adcom "no" vote (& Translarna rejection) I want to see $PTCT sue the FDA $SRPT"
X Link 2017-09-28T14:54Z 27.7K followers, [--] engagements

"Guess what An investigator-sponsored talacotuzumab study was suspended three months ago $JNJ $XNCR"
X Link 2017-10-17T13:11Z 27.7K followers, [--] engagements

"So the anti-CD123 pipeline is whittled down further still $JNJ $XNCR $CLLS $NVS $STML $FBIO $SGEN $MGNX"
X Link 2017-10-17T13:23Z 27.7K followers, [--] engagements

"Get Carta Yescarta $KITE $GILD"
X Link 2017-10-19T05:40Z 27.7K followers, [--] engagements

"$KYKOF Poteligeo (mogamulizumab) beats Zolinza in CTCL patients irrespective of CCR4 expression #ASH17"
X Link 2017-12-10T13:04Z 29.9K followers, [--] engagements

"Note the conditions to $TKPYY 's acquisition of $TIG - EU approval of Cx601 & no material adverse events"
X Link 2018-01-05T09:45Z 27.7K followers, [--] engagements

"$ESRX $CVX $HUM $UNH $ANTM"
X Link 2018-01-30T13:21Z 27.7K followers, [--] engagements

"Spartan results via Eric Small. Apalutamide largely irrelevant given Zytiga's advancement up prostate cancer treatment cascade #GU18 $JNJ"
X Link 2018-02-05T22:44Z 27.7K followers, [--] engagements

"Quite the discrepancy in Immotion-151 between investigator-assessed and independently reviewed PFS $RHHBY $BMY $EXEL $PFE"
X Link 2018-02-06T14:05Z 27.7K followers, [--] engagements

"2018's biggest binary outcome event What to look for from the Echo-301 trial via @EPVantage $INCY http://bit.ly/2EnJCqf http://bit.ly/2EnJCqf"
X Link 2018-02-12T15:44Z 27.7K followers, [--] engagements

"So oncolytic viruses are back in vogue $MRK"
X Link 2018-02-21T09:02Z 27.7K followers, [--] engagements

"$PFE to $CLLS just now"
X Link 2018-04-03T12:02Z 27.7K followers, [--] engagements

"Surprise $ABLX $SNY https://x.com/bio_clouseau/status/981517553913692160 $ABLX No other interest apart from $SNY $NVO https://t.co/y2zjlymfwe https://t.co/ZLYUL9dlER https://x.com/bio_clouseau/status/981517553913692160 $ABLX No other interest apart from $SNY $NVO https://t.co/y2zjlymfwe https://t.co/ZLYUL9dlER"
X Link 2018-04-04T13:06Z 29.9K followers, [--] engagements

"(To the extent that it still matters) is anyone bothered by this $BMY touting TMB-high data from [---] out of a total [----] subjects enrolled into CM-227 #AACR18 $MRK"
X Link 2018-04-16T14:22Z 27.7K followers, [--] engagements

"$LLY $ARMO https://x.com/jacobplieth/status/978611761543831552 https://x.com/jacobplieth/status/978611761543831552"
X Link 2018-05-10T14:27Z 27.7K followers, [--] engagements

"$MRK KN-407: Keytruda ORR 58.4% vs 35.5% p=0.0004. Nothing on survival in abstract #ASCO18 Note $RHHBY IMP-131 is late-breaker"
X Link 2018-05-16T21:01Z 27.7K followers, [--] engagements

"AM0010 in NSCLC #ASCO18 $LLY smart to buy $ARMO when it did"
X Link 2018-05-16T21:01Z 27.7K followers, [--] engagements

"Keytruda KN-158 study in SCLC $MRK #ASCO18 Relevant for followers of upcoming $RHHBY IMP-133 & $BMY CM-451 readouts"
X Link 2018-05-16T21:01Z 27.7K followers, [--] engagements

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creator/x::JacobPlieth
/creator/x::JacobPlieth