#  @CommsMedicine Communications Medicine Communications Medicine posts on X about countries, health, people with, vivo the most. They currently have [-----] followers and [---] posts still getting attention that total [---] engagements in the last [--] hours. ### Engagements: [---] [#](/creator/twitter::1271104673630621696/interactions)  - [--] Week [-----] +449% - [--] Month [-----] +57% - [--] Months [-------] +628% - [--] Year [-------] +135% ### Mentions: [--] [#](/creator/twitter::1271104673630621696/posts_active)  - [--] Week [--] +50% - [--] Month [--] +59% - [--] Months [---] -43% - [--] Year [---] +31% ### Followers: [-----] [#](/creator/twitter::1271104673630621696/followers)  - [--] Months [-----] +1.10% - [--] Year [-----] +2.50% ### CreatorRank: undefined [#](/creator/twitter::1271104673630621696/influencer_rank)  ### Social Influence **Social category influence** [countries](/list/countries) [technology brands](/list/technology-brands) [finance](/list/finance) [travel destinations](/list/travel-destinations) [stocks](/list/stocks) [musicians](/list/musicians) [currencies](/list/currencies) **Social topic influence** [countries](/topic/countries), [health](/topic/health), [people with](/topic/people-with), [vivo](/topic/vivo), [india](/topic/india), [prediction](/topic/prediction), [is a](/topic/is-a), [meta](/topic/meta), [events](/topic/events), [multi](/topic/multi) **Top accounts mentioned or mentioned by** [@naturecomms](/creator/undefined) [@scireports](/creator/undefined) [@commspsychol](/creator/undefined) [@vigeotx](/creator/undefined) [@jingwatnick](/creator/undefined) [@naturemedicine](/creator/undefined) [@commsbio](/creator/undefined) [@commseng](/creator/undefined) [@fionakolbinger](/creator/undefined) [@jnkath](/creator/undefined) [@googlehealth](/creator/undefined) [@jhubme](/creator/undefined) [@hopkinsengineer](/creator/undefined) [@nesmathioudakis](/creator/undefined) [@abrarah84](/creator/undefined) [@leelinglim1](/creator/undefined) [@mariolucam](/creator/undefined) [@drronaldma1](/creator/undefined) [@endohopkins](/creator/undefined) [@maria1969gomez](/creator/undefined) **Top assets mentioned** [Alphabet Inc Class A (GOOGL)](/topic/$googl) ### Top Social Posts Top posts by engagements in the last [--] hours "Machine-learning of medical cannabis chemical profiles reveals analgesia beyond placebo expectations Communications Medicine Hatav et al. use machine learning to analyze chemical profiles of medical cannabis cultivars and their association to pain relief outcomes. Authors find that specific terpenoids predict pain relief outcomes in people with chronic pain providing evidence for compound-specific therapeutic effects beyond placebo responses" [X Link](https://www.nature.com/articles/s43856-025-00996-3) 2025-08-09T11:40Z 208.1M followers, [---] engagements "Approaches to ensure an equitable and fair admissions process for medical training Communications Medicine Anachebe et al. discuss how to center equity in medical school admissions by presenting an equity-based framework that focuses on recruiting standards selection and support. Their recommended strategies are universally applicable across training programs and are accompanied by a number of promising examples" [X Link](https://www.nature.com/articles/s43856-024-00697-3) 2025-04-15T12:01Z 208.1M followers, [--] engagements "Achieving inclusive healthcare through integrating education and research with AI and personalized curricula Communications Medicine Bahmani Cha Alavi Dixit et al. evaluate an AI-facilitated precision medicine learning platform they built Stanford Data Ocean. The platform which provided [----] costfree certification accesses across [--] countries demonstrates positive training outcomes across bioinformatics topics for low and middle income learners" [X Link](https://www.nature.com/articles/s43856-025-01034-y) 2025-09-03T09:14Z 228.6M followers, [---] engagements "Visceral adipose tissue and hepatic fat as determinants of carotid atherosclerosis Communications Medicine de Souza et al. examine whether visceral adipose tissue (VAT) and hepatic fat (HF) are related to carotid atherosclerosis beyond traditional cardiovascular risk factors. Findings reveal that higher VAT and HF are linked to cardiovascular risks such as hypertension diabetes and high cholesterol as well as increased carotid atherosclerosis" [X Link](https://www.nature.com/articles/s43856-025-01123-y) 2025-10-19T15:12Z 208.1M followers, [--] engagements "Computational pathology identifies immune-mediated collagen disruption to predict clinical outcomes in gynecologic malignancies Communications Medicine Aggarwal et al. develop a computational pathology tool to quantitatively characterize the immune-collagen relationship in gynecological cancers. The tool enables the prognostic stratification of patients and provides insights into the biology of the tumor microenvironment" [X Link](https://www.nature.com/articles/s43856-023-00428-0) 2024-01-23T07:00Z 208.1M followers, [---] engagements "Reporting guidelines in medical artificial intelligence: a systematic review and meta-analysis Communications Medicine Kolbinger Veldhuizen et al. systematically review reporting guidelines for artificial intelligence (AI) methods in clinical research. They identify several essential commonly recommended items on study design and model performance while other items are specific to particular fields and research stages" [X Link](https://www.nature.com/articles/s43856-024-00492-0) 2024-04-15T15:30Z 208.1M followers, [---] engagements "Associations between skeletal muscle strength and chronic kidney disease in patients with MASLD Communications Medicine Zhang and Gu used four cohorts to examine associations between skeletal muscle strength (SMS) and chronic kidney disease (CKD) in people with metabolic dysfunction-associated steatotic liver disease (MASLD). Higher handgrip/muscle strength is closely associated with a lower prevalence and incidence of CKD in people with MASLD" [X Link](https://www.nature.com/articles/s43856-025-00821-x) 2025-05-06T11:31Z 208.1M followers, [--] engagements "Parasagittal dural volume correlates with cerebrospinal fluid volume and developmental delay in children with autism spectrum disorder - Communications Medicine Agarwal et al. apply a semi-supervised 2D U-Net to extract the volume of parasagittal dura in young kids with autism spectrum disorder. Positive correlation with cerebrospinal fluid volume and a negative correlation with severity of developmental delay suggests perturbed fluid dynamics" [X Link](https://www.nature.com/articles/s43856-024-00622-8) 2024-10-04T00:00Z 208.1M followers, [---] engagements "First-in-human phase I dose escalation trial of the first-in-class tumor microenvironment modulator VT1021 in advanced solid tumors Communications Medicine Mahalingam et al. report findings from a first-in-human dose escalation study of the tumor microenvironment modulator VT1021 in patients with advanced solid tumors. VT1021 is found to be safe and well tolerated and the recommended phase II dose is established based on pharmacokinetic/dynamic properties and preliminary clinical activities" [X Link](https://www.nature.com/articles/s43856-024-00433-x) 2024-02-06T13:00Z 208.1M followers, [---] engagements "Efficacy of monoclonal antibodies and maternal vaccination for prophylaxis of respiratory syncytial virus disease Communications Medicine Plock et al. integrate clinical efficacy data on monoclonal antibodies and maternal vaccination for prevention of RSV disease in infants. Monoclonal antibodies are predicted to be more efficacious than maternal vaccination in preterm and full-term infants with maternal vaccination expected to partially protect full-term infants born just before or during an RSV season" [X Link](https://www.nature.com/articles/s43856-025-00807-9) 2025-05-06T11:01Z 208.1M followers, [--] engagements "Mini-GRID therapy delivers optimised spatially fractionated radiation therapy using a flattening free filter accelerator Communications Medicine Acuña et al. develop mini-GRID to optimally deliver spatially fractionated radiation therapy using a flattening filter-free linear accelerator. Authors demonstrate its feasibility and reduction in side effects on normal tissues through longitudinal MRI imaging behavioural tests histopathology and infrared microspectroscopy in rat brain tissue" [X Link](https://www.nature.com/articles/s43856-025-00809-7) 2025-04-29T11:01Z 208.1M followers, [--] engagements "Multidimensional sleep profiles via machine learning and risk of dementia and cardiovascular disease Communications Medicine Cavaillès et al. identify three sleep/circadian profiles in older men and examine their links to health outcomes. Compared to the Active Healthy Sleepers group the Fragmented Poor Sleepers group shows higher risks of dementia and cardiovascular disease (CVD) while the Long and Frequent Nappers group shows a trend toward increased CVD risk only" [X Link](https://www.nature.com/articles/s43856-025-01019-x) 2025-08-18T11:31Z 208.1M followers, [---] engagements "Deep learning analysis of epicardial adipose tissue to predict cardiovascular risk in heavy smokers Communications Medicine Foldyna et al. demonstrate that deep learning-based quantification of epicardial adipose tissue from low-dose chest CT scans independently predicts all-cause and cardiovascular mortality in heavy smokers. This can enhance cardiovascular risk stratification beyond traditional measures" [X Link](https://www.nature.com/articles/s43856-024-00475-1) 2024-03-26T19:00Z 208.1M followers, [---] engagements "Development and multicenter validation of on-site breast cancer diagnosis using paper spray ionization miniature mass spectrometry Communications Medicine Huang Chung et al. develop the MiniMaP platform a miniature mass spectrometer coupled with paper spray ionization enabling rapid breast cancer diagnosis from core needle biopsy samples. The machine learning model trained on molecular profiles maintains consistent accuracy in multi centre validation" [X Link](https://www.nature.com/articles/s43856-025-00930-7) 2025-07-20T14:44Z 208.1M followers, [--] engagements "Application of simultaneous uncertainty quantification and segmentation for oropharyngeal cancer use-case with Bayesian deep learning Communications Medicine Sahlsten et al. systematically evaluate two Bayesian deep learning methods and eight uncertainty measures for the segmentation of oropharyngeal cancer primary gross tumor volume with a multi-institute PET/CT dataset. The uncertainty-aware approach can accurately predict the segmentation quality that enables automatic segmentation quality control" [X Link](https://www.nature.com/articles/s43856-024-00528-5) 2024-06-20T05:00Z 208.1M followers, [---] engagements "Individualized cerebellar damage predicts the presence of behavioral disorders in children with brainstem tumors Communications Medicine Jia et al. employ a normative model to identify cerebellar damage patterns in children with brainstem tumors. Machine learning reveals that individualized cerebellar deviations predict social problems and withdrawn behaviours in these patients" [X Link](https://www.nature.com/articles/s43856-025-00810-0) 2025-04-14T12:32Z 208.1M followers, [--] engagements "The unprecedented Paxlovid journey from milligrams to millions of patient doses during the Covid-19 pandemic Communications Medicine Yu et al. describe the challenges faced in the rapid development and upscaling of Paxlovid to meet the global demand for COVID-19 treatment. They respond to challenges by investing at risk integrating predictive tools in development strategy and implementing a diversified global supply chain" [X Link](https://www.nature.com/articles/s43856-025-00798-7) 2025-04-16T12:11Z 208.1M followers, [--] engagements "Development and prospective validation of an artificial intelligence-based smartphone app for rapid intraoperative pituitary adenoma identification Communications Medicine Bou-Nassif et al. develop a smartphone app using AI and stimulated Raman histology to differentiate pituitary adenomas from normal tissue in real-time during surgery. Prospective validation on [--] patients shows high sensitivity and specificity with an external validation on [--] additional adenoma tumors" [X Link](https://www.nature.com/articles/s43856-024-00469-z) 2024-03-29T07:00Z 208.1M followers, [----] engagements "Interpretable machine learning leverages proteomics to improve cardiovascular disease risk prediction and biomarker identification Communications Medicine Climente-González Oh et al. introduce an interpretable machine learning model that integrates plasma proteomics with clinical risk factors and employs an explainable boosting machine algorithm for risk prediction. Authors show that their model outperforms existing models in predicting risk for cardiovascular disease" [X Link](https://www.nature.com/articles/s43856-025-00872-0) 2025-06-09T11:31Z 208.1M followers, [--] engagements "Accurate and interpretable drug-drug interaction prediction enabled by knowledge subgraph learning Communications Medicine Wang Yang et al. propose KnowDDI a graph neural network that leverages biomedical knowledge graphs for drug-drug interaction predictions. The model yields improved performance and interpretability over existing methods especially in scenarios with sparse knowledge graphs marking a significant advancement in biomedicine and healthcare" [X Link](https://www.nature.com/articles/s43856-024-00486-y) 2024-04-08T18:00Z 208.1M followers, [---] engagements "Multi-modal Neuroimaging Phenotyping of Mnemonic Anosognosia in the Aging Brain Communications Medicine Bueichekú et al. use multimodal in vivo neuroimaging to investigate the brain characteristics of individuals presenting unawareness of memory loss who are at risk of Alzheimer’s disease due to age. They find unawareness of memory decline is an early behavioral sign that a person might develop Alzheimer’s disease" [X Link](https://www.nature.com/articles/s43856-024-00497-9) 2024-04-10T12:30Z 208.1M followers, [---] engagements "Computer vision detects covert voluntary facial movements in unresponsive brain injury patients Communications Medicine Cheng et al. developed a computer vision tool (SeeMe) that detects low-amplitude facial movements in comatose brain injury patients. Purposeful responses are detected days before clinical detection suggesting that covert consciousness may often go unrecognized" [X Link](https://www.nature.com/articles/s43856-025-01042-y) 2025-09-02T14:11Z 2.1M followers, 45.3K engagements "The World Trade Center exposome and health effects in 9/11 rescue and recovery workers Communications Medicine Rechtman et al. analyse the exposome of rescue and recovery workers who attended the World Trade Center on and after September [--] [----]. Mental and physical health outcomes associate with all aspects of occupational history as well as traumatic and environmental exposures" [X Link](https://www.nature.com/articles/s43856-024-00683-9) 2025-09-11T03:15Z 208.1M followers, [--] engagements "Harnessing artificial intelligence to improve clinical trial design Communications Medicine Zhang et al. discuss how artificial intelligence (AI) can be used to optimize clinical trial design and potentially boost the success rate of clinical trials. AI has unparalleled potential to leverage real-world data and unlock valuable insights for innovative trial design" [X Link](https://www.nature.com/articles/s43856-023-00425-3) 2024-01-05T14:00Z 208.1M followers, [---] engagements "Oxygen supplementation in anesthesia can block FLASH effect and anti-tumor immunity in conventional proton therapy Communications Medicine Iturri Bertho et al. analyze the effects of oxygen administration during anesthesia in conventional and FLASH proton therapy in a rat model. They demonstrate the detrimental effect of varying oxygen supply using histologic cytometric and behavioral analysis and highlighting the urgent need to optimize anesthesia protocols in pediatric oncology" [X Link](https://www.nature.com/articles/s43856-023-00411-9) 2024-01-18T19:00Z 208.1M followers, [---] engagements "Plasmonic nano-aperture label-free imaging of single small extracellular vesicles for cancer detection Communications Medicine Ohannesian Mallick et al. demonstrate label-free counting and detection of microRNA cargoes for single small extracellular vesicles (sEVs) revealing elevated sEV counts and distinct molecular contents in samples from patients with cancer. Using a simple threshold of sEV count in a blind test classification of cancer vs. healthy samples is achieved with high sensitivity and specificity" [X Link](https://www.nature.com/articles/s43856-024-00514-x) 2024-06-06T16:00Z 208.1M followers, [---] engagements "High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis Communications Medicine Røssevold et al. identify a subset of patients with early-stage basal-like breast cancer with an excellent prognosis defined by high tumor expression of the immune checkpoint gene CTLA4. These patients are currently considered high-risk and receive extensive systemic treatment which the authors suggest could safely be de-escalated or omitted" [X Link](https://www.nature.com/articles/s43856-025-00865-z) 2025-07-06T12:01Z 208.1M followers, [---] engagements "Small extracellular vesicles in follicular fluids for predicting reproductive outcomes in assisted reproductive technology Communications Medicine Muraoka et al. assess the potential of small non-coding RNAs derived from small extracellular vesicles contained within ovarian follicular fluid to determine in predicting assisted reproductive technology outcomes. They find that a combination of small ncRNAs were differentially expressed between reproductive outcomes" [X Link](https://www.nature.com/articles/s43856-024-00460-8) 2024-03-04T11:00Z 208.1M followers, [---] engagements "Impact of gallbladder hypoplasia on hilar hepatic ducts in biliary atresia Communications Medicine Miyazaki Takami et al. assess the relationship between biliary atresia and the gallbladder in Sox17 haploinsufficient mice and human biliary atresia patients. They report findings on the perinatal pathological condition in which abnormalities in the gallbladder wall extend to the intrahepatic bile duct through the common hepatic duct" [X Link](https://www.nature.com/articles/s43856-024-00544-5) 2024-06-24T08:00Z 208.1M followers, [---] engagements "Noninvasive and reliable automated detection of spreading depolarization in severe traumatic brain injury using scalp EEG - Communications Medicine Chamanzar et al. demonstrate the feasibility of using an automated algorithm to non-invasively detect spreading depolarizations in patients with severe traumatic brain injuries. With further testing the algorithm could be a useful tool in the prognostication of worsening brain injuries enabling clinicians to tailor treatments" [X Link](https://www.nature.com/articles/s43856-023-00344-3) 2023-08-19T00:00Z [----] followers, [---] engagements "Machine learning models identify predictive features of patient mortality across dementia types Communications Medicine Zhang Song et al. develop machine-learning models to predict dementia patient mortality at one- three- five- and ten-year thresholds. The models identify dementia patients at risk of mortality using a limited set of dementia-related predictors and the stratified analyses reveal shared and distinct predictors of mortality across dementia types" [X Link](https://www.nature.com/articles/s43856-024-00437-7) 2024-03-04T14:00Z 208.1M followers, [---] engagements "Estimating the risk of brain metastasis for patients newly diagnosed with cancer Communications Medicine Miccio et al. utilize the US National Cancer Database (NCDB) to develop models to estimate the risk of brain metastasis for newly-diagnosed cancers. They provide nomograms and a web tool for risk estimation across multiple cancer types" [X Link](https://www.nature.com/articles/s43856-024-00445-7) 2024-02-23T13:00Z 208.1M followers, [---] engagements "Unravelling the complex causal effects of substance use behaviours on common diseases Communications Medicine Xue et al. use [--] Mendelian Randomization methods to investigate the causal relationship between seven substance use behavioural traits and health outcomes. They identify risk effects of alcohol consumption as well as dosage dependent effects of coffee and tea on cardiovascular disease and osteoarthritis respectively" [X Link](https://www.nature.com/articles/s43856-024-00473-3) 2024-03-26T11:00Z 208.1M followers, [---] engagements "Variant calling from RNA-Seq data reveals allele-specific differential expression of pathogenic cancer variants Communications Medicine Bollas and Gaither et al. present a method to classify simple germline and somatic sequence variants called from tumor RNA sequencing data alone. This machine learning-based approach simplifies variant classification and illustrates the importance of RNA in cancer molecular profiling" [X Link](https://www.nature.com/articles/s43856-025-00901-y) 2025-06-20T09:48Z 208.1M followers, [--] engagements "A nationwide study of risk factors for long COVID and its economic and mental health consequences in the United States Communications Medicine Kim identifies risk factors for long COVID and links long COVID to higher instances of job loss financial hardship and anxiety and depressive symptoms. Lost earnings due to long COVID among working-aged adults are estimated to total $218 billion in [----] indicating long COVID’s substantial public health and economic consequences among Americans" [X Link](https://www.nature.com/articles/s43856-025-00759-0) 2025-04-09T21:36Z 228.6M followers, [----] engagements "Acquired resistance to immune checkpoint therapy is caused by glycoprotein non-metastatic melanoma protein B signal cascade Communications Medicine Chung et al. examine the levels of glycoprotein non-metastatic melanoma protein B (GPNMB) in the blood of patients with renal cell carcinoma who acquire resistance to immune checkpoint inhibitor therapy. Findings show that GPNMB levels are elevated and could serve as a prognosticator of and potential treatment target for treatment-resistant cancer" [X Link](https://www.nature.com/articles/s43856-025-00786-x) 2025-04-10T12:00Z 208.1M followers, [--] engagements "The impact of prematurity on pediatric asthma morbidity and indices with environmental pollution and genetic susceptibility Communications Medicine Kelchtermans et al. analyze interactions between prematurity PM2.5 exposure and genetic susceptibility on asthma exacerbations in children. They find that combined effects produce outsized increases in exacerbation risk underscoring the need for targeted interventions" [X Link](https://www.nature.com/articles/s43856-025-01041-z) 2025-08-22T11:45Z 208.1M followers, [--] engagements "Shifts in ophthalmic care utilization during the COVID-19 pandemic in the US Communications Medicine Li et al. use an analytic framework to identify care utilization patterns for [---] ocular diagnoses in the first two years of the COVID-19 pandemic in the US. Findings reveal lasting utilization reductions for most conditions particularly less severe ones with notable outliers and variations across diagnosis categories and pandemic sub-periods" [X Link](https://www.nature.com/articles/s43856-023-00416-4) 2024-01-15T13:00Z 208.1M followers, [---] engagements "Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series Communications Medicine Cohen et al. report a patient-led case series of [--] individuals with Long COVID who initiated extended courses of Paxlovid outside of or within the context of an acute SARS-CoV-2 infection. Long courses of nirmatrelvir/ritonavir have meaningful benefits for some people with Long COVID but not all" [X Link](https://www.nature.com/articles/s43856-024-00668-8) 2025-01-12T13:19Z 208.1M followers, [---] engagements "Overcoming challenges in the economic evaluation of interventions to optimise antibiotic use Communications Medicine Roope et al. discuss the importance of accounting for the broad benefits that occur as a consequence of optimising antibiotic use. They propose a threshold-based approach that estimates the minimum costs that would need to be averted by an intervention to make it cost-effective" [X Link](https://www.nature.com/articles/s43856-024-00516-9) 2024-05-30T11:00Z 208.1M followers, [---] engagements "Humoral and cellular immune responses to COVID-19 mRNA vaccines in immunosuppressed liver transplant recipients Communications Medicine Nogimori Nagatsuka et al. present a longitudinal immunogenicity analysis of mRNA vaccination in liver transplant recipients and healthy donors. Despite a lower response to primary vaccination in transplant recipients a third booster improves antibody- and CD4 T cell-responses but not CD8 T cell-responses which need further improvement" [X Link](https://www.nature.com/articles/s43856-024-00448-4) 2024-03-05T07:00Z 208.1M followers, [---] engagements "A comprehensive overview of the burden prevention and therapeutic aspects of arboviral diseases in India Communications Medicine Gupta et al. discuss the epidemiology and burden of major circulating arboviral diseases in India touching on diagnosis treatment and preventative measures. They highlight key research and policy gaps along with direction for future research to improve surveillance and control measures" [X Link](https://www.nature.com/articles/s43856-025-00968-7) 2025-07-21T11:07Z 208.1M followers, [--] engagements "Projecting future fluid intake of Chinese children in a warming world Communications Medicine Zhu He Zhang et al. conduct a cross-sectional study examining the relationship between temperature and fluid intake in Chinese children. Findings reveal a 24 mL daily intake increase per 1 °C temperature rise and projections under climate change scenarios predict substantially higher hydration needs by 2099" [X Link](https://www.nature.com/articles/s43856-025-00929-0) 2025-06-24T11:31Z 208.1M followers, [--] engagements "Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimers disease patients Communications Medicine Yaghmaei et al. utilize doubly robust causal inference estimators and a large medical data set to evaluate the impact of combining Donepezil and Memantine on five-year survival since initial diagnosis of Alzheimer’s disease patients. A significant benefit to survival is seen when the drugs are combined" [X Link](https://www.nature.com/articles/s43856-024-00527-6) 2024-06-06T10:00Z 208.1M followers, [---] engagements "Sepsis endotypes identified by host gene expression across global cohorts Communications Medicine Chenoweth et al. investigate heterogeneity in sepsis using host gene expression from multi-site international cohorts. Endotypes differentiated by mortality are identified and related molecular signatures implicate immune dysfunction in sepsis pathophysiology" [X Link](https://www.nature.com/articles/s43856-024-00542-7) 2024-06-28T11:30Z 208.1M followers, [---] engagements "Mendelian randomization study of the relationship between blood and urine biomarkers and schizophrenia in the UK Biobank cohort Communications Medicine Cheng Bai et al. uncover associations between [--] blood and urine biomarkers and treatment-resistant schizophrenia using data from the UK Biobank. They find correlations between some blood and urine biomarkers and treatment resistant schizophrenia polygenic risk scores" [X Link](https://www.nature.com/articles/s43856-024-00467-1) 2024-03-13T08:00Z 208.1M followers, [---] engagements "Meal timing trajectories in older adults and their associations with morbidity genetic profiles and mortality Communications Medicine Dashti et al. characterize whether meal timing changes with age in older adults using longitudinal data from nearly [----] individuals. They link later breakfast timing with increased multimorbidity and higher mortality risk and reveal behavioral and genetic factors that influence meal timing during aging" [X Link](https://www.nature.com/articles/s43856-025-01035-x) 2025-09-05T12:28Z 228.6M followers, [---] engagements "Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome Communications Medicine Sighinolfi et al. evaluate the ovarian reserve in young healthy women with hereditary breast and/or ovarian cancer (HBOC) syndrome. A consistent trend for reduced reproductive potential in young healthy women with HBOC syndrome is observed particularly in BRCA1 pathogenic/likely-pathogenic variant carriers" [X Link](https://www.nature.com/articles/s43856-025-00788-9) 2025-04-07T11:31Z 208.1M followers, [---] engagements "Lifestyle and demographic associations with [--] inflammatory and vascular stress biomarkers in [----] blood donors Communications Medicine Kjerulff et al. evaluate [--] biomarkers including markers of inflammation and vascular stress and their associations with demographic and lifestyle factors in healthy participants from the Danish Blood Donor study. Circulating biomarker levels varied according to sex age BMI and smoking status" [X Link](https://www.nature.com/articles/s43856-024-00474-2) 2024-04-01T07:00Z 208.1M followers, [---] engagements "Description of an activity-based enzyme biosensor for lung cancer detection Communications Medicine Dempsey et al. present a graphene-based biosensor technology to detect enzyme activity in serum samples. A model is developed based on the activity of a panel of these biosensors to classify 90% of patients with lung cancer across all stages of disease providing a potentially useful screening technology" [X Link](https://www.nature.com/articles/s43856-024-00461-7) 2024-03-12T09:00Z 208.1M followers, [---] engagements "Temporal trends of blood-based markers in various psychiatric disorders and their cross-sectional brain structure associations Communications Medicine Wang Zhou et al. conduct a nested case-control study within the UK Biobank cohort to investigate the temporal trends of blood-based biomarkers across major psychiatric disorders. They report significant temporal alterations in biomarkers and their associations with cross-sectional structural variations in specific brain regions highlighting disease-specific neurobiological correlates" [X Link](https://www.nature.com/articles/s43856-025-00957-w) 2025-07-08T12:32Z 208.1M followers, [--] engagements "Preserving fairness and diagnostic accuracy in private large-scale AI models for medical imaging Communications Medicine Tayebi Arasteh Ziller et al. investigate how strict privacy safeguards affect AI learning in medical imaging. Their study finds that while enforcing privacy leads to a modest drop in accuracy it does not exacerbate biases for different patient groups though accuracy for intricate cases and specific subgroups may be more affected" [X Link](https://www.nature.com/articles/s43856-024-00462-6) 2024-03-27T08:00Z 208.1M followers, [---] engagements "Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer Communications Medicine Laurent et al. develop a liver-targeted gene therapy using recombinant adeno-associated viral vector (rAAV) to effectively cure Lysosomal acid lipase deficiency. This occurs via correction of lipid accumulation and normalized gene expression patterns and mitochondrial function in Lipa−/− mice" [X Link](https://www.nature.com/articles/s43856-025-00816-8) 2025-05-02T11:01Z 208.1M followers, [--] engagements "Metformin use on the risks of depression and anxiety in people with type [--] diabetes Communications Medicine Kang Liu et al. evaluate the link between metformin use and depression in type [--] diabetes mellitus (T2DM) patients. Findings reveal that T2DM patients using metformin have a lower risk of depression and genetic analysis identifies KCNIP4 and BTG3 as key genes influencing this effect" [X Link](https://www.nature.com/articles/s43856-025-01006-2) 2025-08-20T12:31Z 208.1M followers, [--] engagements "Enhanced fetal hematopoiesis in response to symptomatic SARS-CoV-2 infection during pregnancy Communications Medicine Alkobtawi Ngô et al. conduct transcriptome and phenotype analyses of umbilical cord blood cells from pregnant women upon SARS-CoV-2 infection. In the absence of vertical SARS-CoV-2 transmission erythroid cell signatures along with hypoxia pathway activation are observed in symptomatic infected mothers compared with control cases" [X Link](https://www.nature.com/articles/s43856-023-00406-6) 2024-01-08T07:00Z [----] followers, [---] engagements "Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model Communications Medicine Renner et al. evaluate the impacts of different types of glycan moieties on the immunogenicity of SARS-CoV-2 spike in a mouse model. The presence of complex type glycans correlate with increased levels of neutralizing antibodies" [X Link](https://www.nature.com/articles/s43856-025-00830-w) 2025-05-02T11:31Z 208.1M followers, [--] engagements "Respiratory modulations of cortical excitability and interictal spike timing in focal epilepsy: a case report Communications Medicine Kluger et al. investigate respiratory modulations of cortical excitability states in a patient with focal epilepsy using high-resolution magnetoencephalography. Respiration differentially modulates excitation-inhibition balance in focal epilepsy and the timing of epileptic spike generation depends on both excitability and respiratory states" [X Link](https://www.nature.com/articles/s43856-025-00811-z) 2025-05-01T12:01Z 208.1M followers, [--] engagements "Pretrained patient trajectories for adverse drug event prediction using common data model-based electronic health records Communications Medicine Kim et al. develop an adverse drug event (ADE) prediction model using language model-based electronic health records (EHR) pretraining model. Authors show that EHR pretraining models can accurately predict ADEs with proper explanations" [X Link](https://www.nature.com/articles/s43856-025-00914-7) 2025-07-02T17:12Z 208.1M followers, [---] engagements "Utilizing Google Trends data to enhance forecasts and monitor long COVID prevalence Communications Medicine Chu et al. use merged search volumes of long COVID symptoms derived from Google Trends data to investigate changing search patterns. Several specific symptoms increase in searches both before and after the rise in the searches for long COVID suggesting that search volumes can predict long COVID prevalence" [X Link](https://www.nature.com/articles/s43856-025-00896-6) 2025-05-27T12:01Z 208.1M followers, [---] engagements "Identifying commonalities and differences between EHR representations of PASC and ME/CFS in the RECOVER EHR cohort Communications Medicine Powers et al. investigate commonalities and differences between electronic health record patterns associated with post-acute sequelae of SARS-CoV-2 infection and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Records of dyspnea fatigue and cognitive impairment are common diagnoses and recommend common symptom management" [X Link](https://www.nature.com/articles/s43856-025-00827-5) 2025-05-01T12:31Z 208.1M followers, [--] engagements "Identifying outbreak risk factors through case-controls comparisons Communications Medicine Fefferman et al. propose applying a case-control framework as an outbreak epidemiological study design to promote evidence-based decision-making for prevention and response to outbreaks. They describe their framework and discuss case-control examples of how it can be applied" [X Link](https://www.nature.com/articles/s43856-025-00916-5) 2025-06-19T09:44Z 208.1M followers, [---] engagements "Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer Communications Medicine Herzog et al. dissect functionally enriched groups of CpG associated with cellular senescence proliferation and aging. Some non-cancer tissues from breast cancer patients show younger epigenetic ages than in controls while breast cancer tissue looks generally older providing evidence for discordant systemic aging in breast cancer" [X Link](https://www.nature.com/articles/s43856-025-00739-4) 2025-04-24T11:31Z 228.6M followers, [---] engagements "Question-answering system extracts information on injection drug use from clinical notes Communications Medicine Mahbub et al. introduce a question-answering framework to extract injection drug use (IDU) details from unstructured clinical notes. The proposed framework demonstrates high performance and extracts IDU details efficiently facilitating informed care for those who inject drugs" [X Link](https://www.nature.com/articles/s43856-024-00470-6) 2024-05-07T05:30Z 208.1M followers, [---] engagements "Serum metabolite levels identify incipient metastatic progression of rectal cancer Communications Medicine Bakke Bousquet et al. identify serum metabolite biomarkers at the time of primary tumour diagnosis in rectal cancer participants prone to metastatic progression. These individuals show higher serum metabolites of alanine lactate pyruvate and citrate compared to those without metastatic progression" [X Link](https://www.nature.com/articles/s43856-025-00868-w) 2025-05-13T11:31Z 208.1M followers, [--] engagements "Cluster and survival analysis of UK biobank data reveals associations between physical multimorbidity clusters and subsequent depression Communications Medicine DeLong et al. investigate several clustering techniques to identify patterns of physical multimorbidity. They find several clusters which align to known body systems and use survival analyses to determine which clusters are most associated with depression" [X Link](https://www.nature.com/articles/s43856-025-00825-7) 2025-05-21T12:31Z 208.1M followers, [--] engagements "Identifying multi-resolution clusters of diseases in ten million patients with multimorbidity in primary care in England Communications Medicine Beaney et al. compare co-occurrence and sequence-based embedding methods and apply graph-based clustering to identify clusters of diseases at multiple resolutions in over ten million people with multimorbidity. Interpretable clusters of diseases are found that correspond to both established and novel patterns" [X Link](https://www.nature.com/articles/s43856-024-00529-4) 2024-06-04T07:00Z 208.1M followers, [---] engagements "The association between the gut microbiome and 24-h blood pressure measurements in the SCAPIS study Communications Medicine Lin et al. investigate the relationship between specific characteristics of the gut microbiome and 24-h ambulatory blood pressure measurements. Four gut microbial species and microbial diversity associate with 24-h blood pressure traits supporting a potential role for the gut microbiome in blood pressure regulation and variability" [X Link](https://www.nature.com/articles/s43856-025-00980-x) 2025-08-01T11:31Z 208.1M followers, [--] engagements "Mapping multimorbidity progression among [---] diseases - Communications Medicine Han et al. present a framework to map the clusters of multimorbidity progression by examining the bi-directional causal progress between hundreds of diseases. This provides a comprehensive picture of how one disease influences and is influenced by the development of others and how they form clusters of disease trajectories" [X Link](https://www.nature.com/articles/s43856-024-00563-2) 2024-07-11T00:00Z [----] followers, [---] engagements "Transmission risks of Omicron BA.5 following inactivated COVID-19 vaccines among children and adolescents in China Communications Medicine Guo Zeng Lu et al. assess SARS-CoV-2 Omicron BA.5 transmission and protection from inactivated vaccines among children and adolescents prior to the end of Zero-COVID measures in Urumqi China. Two vaccine doses provide improved protection against Omicron infection and reduced transmission versus a single dose when given within the same year" [X Link](https://www.nature.com/articles/s43856-024-00521-y) 2024-05-24T12:00Z 208.1M followers, [---] engagements "Continuous vital sign monitoring of acute Lassa fever using wearable biosensor devices in West Africa Communications Medicine Page et al. use wearable biosensors to monitor vital sign trends in patients with Lassa fever in Sierra Leone. Tachycardia and reduced heart rate variability associate with poor outcomes though technical limitations hinder broader implementation" [X Link](https://www.nature.com/articles/s43856-025-01002-6) 2025-08-07T16:34Z 208.1M followers, [---] engagements "Neutralizing antibodies after the third COVID-19 vaccination in healthcare workers with or without breakthrough infection Communications Medicine Reinholm et al. evaluate COVID-19 vaccine-induced binding and neutralizing antibodies against several SARS-CoV-2 variants [--] months post three doses of vaccines in healthcare workers. Thrice vaccinated individuals could mount an effective humoral response to most variants except for BQ.1.1 and XBB.1.5 emphasizing the need for new vaccine candidates" [X Link](https://www.nature.com/articles/s43856-024-00457-3) 2024-02-28T09:30Z 208.1M followers, [---] engagements "A domain knowledge-based interpretable deep learning system for improving clinical breast ultrasound diagnosis Communications Medicine Yan Liang Zhang et al. propose a domain knowledge-based interpretable deep learning system to improve breast cancer risk prediction from multimodal ultrasound images. Its inherent interpretability enables effective human-machine collaboration and thus may aid clinical decision-making" [X Link](https://www.nature.com/articles/s43856-024-00518-7) 2024-05-21T11:00Z 208.1M followers, [---] engagements "Kindness as a public health action Communications Medicine Nguyen and Lee discuss how universal practice of kindness is a public health action. Using empirical evidence of randomised controlled trials combined with Rose’s theoretical framework of preventive medicine authors propose how acts of kindness specifically self-kindness and self-compassion can improve mental health outcomes" [X Link](https://www.nature.com/articles/s43856-025-00861-3) 2025-05-12T12:01Z 208.1M followers, [--] engagements "A Mendelian randomization analysis of cardiac MRI measurements as surrogate outcomes for heart failure and atrial fibrillation Communications Medicine Schmidt et al. use Mendelian randomization to identify (biventricular) cardiac MRI measurements with a strong association with heart failure and/or atrial fibrillation. Nine cardiac MRI measurements are identified that may be relevant to consider as surrogate outcomes in both research and clinical settings" [X Link](https://www.nature.com/articles/s43856-025-00855-1) 2025-05-13T10:32Z 208.1M followers, [--] engagements "Refining the diagnosis of gestational diabetes mellitus: a systematic review and meta-analysis Communications Medicine Francis et al. perform a systematic review and meta-analysis to evaluate studies comparing perinatal outcomes among individuals with gestational diabetes mellitus (GDM). Their review and post hoc analysis find that maternal preconception weight and non-glucose-dependent biochemical markers could be a precision diagnostic approach to reducing variability in clinical outcomes following treatment" [X Link](https://www.nature.com/articles/s43856-023-00393-8) 2024-01-18T12:00Z 208.1M followers, [--] engagements "Overcoming data scarcity in life-threatening arrhythmia detection through transfer learning Communications Medicine Monachino et al. investigate how to overcome the challenge of data scarcity in life-threatening arrhythmias (LTA) detection. They propose a transfer learning-based deep learning model that detects LTAs from single-lead ECGs with 92.68% sensitivity and 99.48% specificity and includes a confidence score to better support emergency response" [X Link](https://www.nature.com/articles/s43856-025-00982-9) 2025-07-19T14:42Z 208.1M followers, [--] engagements "Pathophysiological profile of non-ventilated lung injury in healthy female pigs undergoing mechanical ventilation Communications Medicine Spinelli et al. show that non-ventilated lung injury develops within 24 h of unilateral mechanical ventilation in healthy pigs. Pathophysiological alterations included collapse hypoperfusion high inspiratory pressure and inflammation and were only partially mitigated by low tidal volume" [X Link](https://www.nature.com/articles/s43856-024-00449-3) 2024-02-21T08:00Z [----] followers, [---] engagements "An ECG-based artificial intelligence model for assessment of sudden cardiac death risk Communications Medicine Holmstrom et al. train and validate a 12 lead ECG-based deep learning algorithm for sudden cardiac death risk assessment. The model accurately distinguishes sudden cardiac death cases from controls performing better than a conventional ECG risk model" [X Link](https://www.nature.com/articles/s43856-024-00451-9) 2024-03-01T17:00Z 208.1M followers, [---] engagements "Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia Communications Medicine Fola et al. perform a nationwide genomic surveillance study of P. falciparum parasites across Zambia from samples collected in [----] and report key genetic metrics informing transmission intensity genetic relatedness and selection. These genomic surveillance data highlight the need to strengthen malaria control and surveillance of drug resistance" [X Link](https://www.nature.com/articles/s43856-024-00498-8) 2024-05-10T12:30Z 208.1M followers, [---] engagements "Real-time motion-enabling positron emission tomography of the brain of upright ambulatory humans Communications Medicine Siva Bauer et al. use a motion-compatible brain imager to detect task-related brain activity in human participants walking in place. The feasibility of positron emission tomography (PET) neuroimaging of people performing motor tasks or who cannot remain still is demonstrated" [X Link](https://www.nature.com/articles/s43856-024-00547-2) 2024-06-26T19:00Z 208.1M followers, [---] engagements "Tracing the origins of Plasmodium vivax resurgence after malaria elimination on Aneityum Island in Vanuatu Communications Medicine Sekine et al. traced the origins ofPlasmodium vivax resurgence after achieving malaria elimination on Aneityum Island Vanuatu. Analyzing five nuclear microsatellite markers samples from the resurgence and nearby Tanna Island exhibit identical or closely related haplotypes suggesting that imported infection contributes to the reintroduction" [X Link](https://www.nature.com/articles/s43856-024-00524-9) 2024-06-10T11:00Z 208.1M followers, [---] engagements "Large language model comparisons between English and Chinese query performance for cardiovascular prevention Communications Medicine Ji et al. assess the responses of four major large language models in the context of cardiovascular disease prevention queries in both English and Chinese. The large language model chatbots exhibit significant disparities in performance across different models and languages with ChatGPT-4 outperforming the others in English" [X Link](https://www.nature.com/articles/s43856-025-00802-0) 2025-05-29T12:31Z 208.1M followers, [---] engagements "Effects of COVID-19 pandemic on low birth weight in a nationwide study in India Communications Medicine Kumar et al. examine differences in birthweight and LBW between the pre COVID-19 (before Jan 2020) and COVID-19 (after March [----] onwards). Infants born during the COVID-19 period had lower birthweight compared to infants born during pre-COVID-19 periods" [X Link](https://www.nature.com/articles/s43856-024-00545-4) 2024-06-27T08:00Z 208.1M followers, [---] engagements "Antimicrobial drug pricing Communications Medicine Despite the constant development of antimicrobial resistance (AMR) few new antimicrobials are currently becoming available clinically. Alternative approaches such as different mechanisms to fund their use are being explored to encourage development of new antimicrobials" [X Link](https://www.nature.com/articles/s43856-024-00594-9) 2024-10-23T10:59Z 208.1M followers, [---] engagements "Structure-specific rigid dose accumulation dosimetric analysis of ablative stereotactic MRI-guided adaptive radiation therapy in ultracentral lung lesions Communications Medicine Bryant et al. report findings of a dosimetric analysis of adapted versus non-adapted radiation therapy plans of ultracentral lung lesions treated with ablative stereotactic MRI-guided adaptive radiation therapy. The differences demonstrated help to elucidate the therapeutic window improvements of daily plan adaptation" [X Link](https://www.nature.com/articles/s43856-024-00526-7) 2024-05-31T11:00Z 208.1M followers, [---] engagements "Machine learning-based health environmental-clinical risk scores in European children Communications Medicine Guimbaud et al. use machine learning in a dataset of [----] European mother-child pairs to link early-life environmental exposures with children’s health. Through the computation of environmental-clinical risk scores they unveil complex interactions and nonlinear patterns among these factors underscoring their intricate role in children’s health" [X Link](https://www.nature.com/articles/s43856-024-00513-y) 2024-06-03T12:00Z 208.1M followers, [---] engagements "Perceptions of the determinants of health across income and urbanicity levels in eight countries Communications Medicine Abdalla et al. examine how demographic factors shape perceptions of what matters for health across eight countries. They show that high income groups rank genetics as important urban groups rank healthcare as important and both low-income groups and non-urban groups rank social support as important" [X Link](https://www.nature.com/articles/s43856-024-00493-z) 2024-06-21T07:00Z 208.1M followers, [---] engagements "Challenges in implementing cultural adaptations of digital health interventions Communications Medicine Nittas et al. discuss the importance of cultural adaptations in eliminating systemic exclusion of traditionally underserved cultural groups to minimize barriers to accessing digital healthcare interventions. They outline the existing challenges of the digital divide and provide recommendations to overcome them" [X Link](https://www.nature.com/articles/s43856-023-00426-2) 2024-01-11T12:00Z 208.1M followers, [---] engagements "Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures Communications Medicine Barrett Herzog and Aminzadeh-Gohari et al. demonstrate that tissue-specific epigenetic DNA methylation signatures define field cancerization and can predict cancer formation even from distant sources. Mifepristone reduced mammary gland cancer risk in mice by over 50% with this effect mirrored in changes to cervical DNA methylation patterns" [X Link](https://www.nature.com/articles/s43856-025-00779-w) 2025-04-25T12:01Z 208.1M followers, [--] engagements "Risk factors for cardiogenic shock incidence and mortality after acute myocardial infarction: a systematic review and meta-analysis Communications Medicine Maimaitiming et al. systematically analyse the correlations between patient-related factors and cardiogenic shock after acute myocardial infarction (AMI-CS). The results reveal the risk factors in predicting the incidence and prognosis of AMI-CS which emphasizes early identification and targeted interventions for high-risk patients" [X Link](https://www.nature.com/articles/s43856-025-00874-y) 2025-06-13T11:31Z 208.1M followers, [--] engagements "Potential influence of geomagnetic activity on blood pressure statistical fluctuations at mid-magnetic latitudes Communications Medicine He et al. analyze the correlation between blood pressure (BP) and geomagnetic activity (GMA) along with their quasi-periodic fluctuations. Their results show a significant positive correlation with multiple periodicities not observed in other factors like temperature and PM2.5 offering further evidence linking GMA and BP fluctuations" [X Link](https://www.nature.com/articles/s43856-025-00822-w) 2025-05-04T12:53Z 2.1M followers, [----] engagements "Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders Communications Medicine Song et al. conduct a geospatial analysis of variations in incidence of mood and psychotic disorders and access to care in Caldas Colombia. They show that many patients requiring only outpatient care live too far away to access it and identify hotspots of more severely ill patients highlighting the need for targeted interventions" [X Link](https://www.nature.com/articles/s43856-024-00441-x) 2024-02-23T16:00Z 208.1M followers, [---] engagements "Association of Lifes Simple [--] lifestyle metric with cardiometabolic disease-free life expectancy in older British men Communications Medicine Wang et al. evaluate the association between adherence to the Life’s Simple [--] lifestyle metrics and cardiometabolic disease (CMD)-free survival in a population of older British men. Men with ideal levels of adherence remained CMD-free for four years longer than those with poor adherence with physical activity providing the greatest benefit" [X Link](https://www.nature.com/articles/s43856-024-00534-7) 2024-06-19T16:00Z 208.1M followers, [---] engagements "Dynamic SARS-CoV-2 surveillance model combining seroprevalence and wastewater concentrations for post-vaccine disease burden estimates Communications Medicine Holm et al. present a SARS-CoV-2 surveillance model linking hospitalization seroprevalence and wastewater concentrations. They fit this model to epidemic data from Kentucky USA to generate counterfactual scenarios highlighting the plausible effects of vaccination and changes in dynamics due to emergence of new variants" [X Link](https://www.nature.com/articles/s43856-024-00494-y) 2024-04-16T11:00Z [----] followers, [---] engagements "A deep network DeepOpacityNet for detection of cataracts from color fundus photographs Communications Medicine Elsawy Keenan Chen et al. detect cataracts from color fundus photography using an explainable deep learning network called DeepOpacityNet. DeepOpacityNet detects cataracts more accurately than ophthalmologists and demonstrates that the absence of blood vessels is an indicator that cataracts are present" [X Link](https://www.nature.com/articles/s43856-023-00410-w) 2024-01-18T08:00Z [----] followers, [---] engagements "Safety and pharmacokinetics of the non-hormonal male contraceptive YCT-529 Communications Medicine Mannowetz et al. evaluate the safety and tolerability of the small molecule YCT-529 and show that single doses of up to 180 mg were well tolerated in healthy male subjects of this Phase 1a clinical trial. YCT-529 is developed as a non-hormonal oral male contraceptive pill with the intention to reduce the risk of unplanned pregnancies" [X Link](https://www.nature.com/articles/s43856-025-01004-4) 2025-07-29T11:53Z 208.1M followers, [--] engagements "Remission of alcohol use disorder following traumatic brain injury with focal orbitofrontal cortex hemorrhage: case report and network mapping Communications Medicine Haque et al. report a case of chronic alcohol use disorder that had early remission following a traumatic brain injury with left orbitofrontal cortex intracerebral hemorrhage. Mapping of this lesion converges on recently described addictive behavior network maps but with inverse connectivity" [X Link](https://www.nature.com/articles/s43856-025-00760-7) 2025-03-13T19:32Z 208.1M followers, [--] engagements "Spatial modeling connecting childhood atopic dermatitis prevalence with household exposure to pollutants Communications Medicine Ratley Zeldin et al. implicate xylene in the pathogenesis of atopic dermatitis by combining spatial analysis and patient surveys with prior epidemiological and mechanistic data. They propose that exposure of healthy skin commensals to xylene benzene and isocyantes in synthetic fabrics disrupts normal lipid metabolism and activates itching" [X Link](https://www.nature.com/articles/s43856-024-00500-3) 2024-04-23T11:00Z 208.1M followers, [---] engagements "Distinct brain morphometry patterns revealed by deep learning improve prediction of post-stroke aphasia severity Communications Medicine Teghipco et al. use deep learning to assess whether the spatial interdependencies of multivariate brain morphometry patterns contain information that can improve prediction of aphasia severity post-stroke. They demonstrate that compared to classical machine learning deep learning gives better predictions" [X Link](https://www.nature.com/articles/s43856-024-00541-8) 2024-06-25T06:00Z 208.1M followers, [---] engagements "Inter-seizure variability in thalamic recruitment and its implications for precision thalamic neuromodulation Communications Medicine Salami et al. explore how seizure properties can guide thalamic modulation site selection in epilepsy. Spiking-pattern seizures show limited thalamic spread while faster (10-20 Hz) broad-onset seizures spread early especially to the centromedian and pulvinar suggesting they are better targets for these seizures than the anterior nucleus" [X Link](https://www.nature.com/articles/s43856-025-00920-9) 2025-06-11T12:02Z 208.1M followers, [--] engagements "Geospatial analysis and scale-up modelling of the impact of mobile programming on access to essential childhood vaccinations in Yemen Communications Medicine Garber et al examine the impact of mobile programming on childhood vaccination access in Yemen using geospatial modelling and conflict-adjusted datasets. The modelling also identifies a set of optimal locations for new vaccination sites and quantifies their potential impact on vaccine accessibility" [X Link](https://www.nature.com/articles/s43856-025-00762-5) 2025-05-09T11:31Z 208.1M followers, [--] engagements "Cardiotoxic profiles of CAR-T therapy and bispecific T-cell engagers in hematological cancers Communications Medicine Karthikeyan et al. use WHO pharmacovigilance data to evaluate cardiotoxicity profiles of CAR-T therapy and bispecific T-cell engagers. They find evidence of severe adverse cardiovascular events including heart failure in some patients treated with tisagenlecleucel" [X Link](https://www.nature.com/articles/s43856-024-00540-9) 2024-06-26T12:00Z 208.1M followers, [---] engagements "Association of SARS-CoV-2 vaccination status with risk of influenza-like illness and loss of workdays in healthcare workers Communications Medicine Dörr Lacy et al. evaluate the association between SARS-CoV-2 vaccination status and influenza-like illness and sick leave among [----] Swiss healthcare workers. SARS CoV-2 vaccination is associated with increased illness symptoms and more days of sick leave while influenza vaccination is associated with a decreased risk of both outcomes" [X Link](https://www.nature.com/articles/s43856-025-01046-8) 2025-08-09T20:33Z 2.1M followers, 114.7K engagements "Determining frailty index thresholds for older people across multiple countries in sub-Saharan Africa Communications Medicine Dzando et al. identify locally relevant frailty thresholds for older people in Sub-Saharan Africa through Receiver Operating Characteristic analysis and random-effects meta-analysis. Findings demonstrate variability in population level thresholds with a pooled threshold of [----] demonstrating good sensitivity and specificity across the populations" [X Link](https://www.nature.com/articles/s43856-025-00952-1) 2025-07-07T12:01Z 208.1M followers, [--] engagements "Recent advances in CRISPR-based single-nucleotide fidelity diagnostics Communications Medicine Kohabir et al. review recent advances in CRISPR-based diagnostics aimed at achieving single-nucleotide fidelity for clinical applications. By dissecting strategies in gRNA design effector selection and reaction conditions the authors highlight how these innovations can support precise and accessible genetic testing at the point-of-care" [X Link](https://www.nature.com/articles/s43856-025-00933-4) 2025-07-25T14:50Z 208.1M followers, [--] engagements "Impact of clinical preparation steps and use of sex-specific reference for accurate antibiotic monitoring in body fluids Communications Medicine Domes et al. use enhanced Raman spectroscopy to quantify drugs within body fluids. Freezing centrifugation and filtration result in additive loss of piperacillin from human urine while using a reference urine pool from same-sex donors yield superior results to a mixed-sex urine pool" [X Link](https://www.nature.com/articles/s43856-025-00823-9) 2025-05-06T12:31Z 208.1M followers, [--] engagements "Long-term immune responses to SARS-CoV-2 Omicron BA.4/5 mRNA booster in people living with HIV Communications Medicine Augello et al. assess long-term immune responses to Omicron BA.4/5 booster in people living with HIV. The vaccine enhances immunity with T cell responses stable and cross-reactive but antibody responses short-lived and imprinted to the ancestral virus; HIV-related T cell dysfunction reduces antibody peak and durability" [X Link](https://www.nature.com/articles/s43856-025-00799-6) 2025-04-18T11:16Z 208.1M followers, [---] engagements "Rabies virus large protein-derived T-cell immunogen facilitates rapid viral clearance and enhances protection against lethal challenge in mice Communications Medicine Bai et al. present a novel mRNA rabies vaccine RABV-G-LT which combines glycoprotein and T-cell immunogens to enhance protection against rabies. This dual-immunogen approach elicits robust neutralizing antibodies and T-cell responses in mice and non-human primates providing a promising strategy for more effective and cost-efficient rabies prevention" [X Link](https://www.nature.com/articles/s43856-025-00851-5) 2025-05-09T12:31Z 208.1M followers, [--] engagements "Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography Communications Medicine Das and colleagues develop and evaluate a parallel discriminator generative adversarial network (P-GAN) for improved in-vivo imaging of retinal cellular structures. The P-GAN network improves retinal pigment epithelium contrast 3.5-fold and the overall throughput 99-fold" [X Link](https://www.nature.com/articles/s43856-024-00483-1) 2024-05-12T12:00Z 208.1M followers, [---] engagements "Predicting which patients with cancer will see a psychiatrist or counsellor from their initial oncology consultation document using natural language processing Communications Medicine Nunez et al. investigate the use of natural language processing to predict which patients with cancer will see a psychiatrist or counselling using the initial oncology consultation document. Their study supports the use of such techniques with widely-available medical documents to better address the psychosocial needs of cancer patients" [X Link](https://www.nature.com/articles/s43856-024-00495-x) 2024-04-15T13:00Z [----] followers, [---] engagements "Proteomic features of soft tissue tumours in adolescents and young adults Communications Medicine Tam et al. compare molecular features between adolescents and young adult (AYA) and older adult (OA) patients with soft tissue tumours and identify that components of the spliceosome complex are independent prognostic factors for metastasis free survival in AYA patients" [X Link](https://www.nature.com/articles/s43856-024-00522-x) 2024-05-22T06:00Z [----] followers, [---] engagements "Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type [--] diabetes: a systematic review Communications Medicine Felton et al. conduct a systematic review to determine the utility of islet autoantibodies as biomarkers of type [--] diabetes heterogeneity. They find that islet autoantibodies are most likely to be useful for patient stratification prior to clinical diagnosis" [X Link](https://www.nature.com/articles/s43856-024-00478-y) 2024-04-11T07:00Z 208.1M followers, [---] engagements "Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization Communications Medicine Morrow et al. evaluate the clinical and social parameters of Scottish patients who were previously admitted to hospital with SARS-CoV-2 infection. They report that socioeconomic deprivation influences illness trajectory after COVID-19" [X Link](https://www.nature.com/articles/s43856-024-00455-5) 2024-03-11T11:00Z 208.1M followers, [---] engagements "Peripheral nerve regeneration following scaffold-free conduit transplant of autologous dermal fibroblasts: a non-randomised safety and feasibility trial Communications Medicine Ikeguchi et al. established nerve conduits from three patients’ dermal fibroblasts using a bioprinter and transplanted them back into the patients’ nerve defects. No adverse events occurred and the nerves recovered following the transplant" [X Link](https://www.nature.com/articles/s43856-024-00438-6) 2024-02-05T08:07Z 208.1M followers, [---] engagements "Cochlear gene therapy restores hearing and auditory processing in an atypical DFNB9 mouse model Communications Medicine Benamer et al. develop a knock-in mouse model carrying the E1799del otoferlin mutation to study the atypical DFNB9 variant form of deafness. They show the mouse model exhibits abnormal otoferlin distribution failure of synaptic transmission in inner hair cells and profound hearing loss all of which can be restored with AAV gene therapy" [X Link](https://www.nature.com/articles/s43856-025-00926-3) 2025-06-27T12:01Z 208.1M followers, [--] engagements "Utility and cost-effectiveness of LiverMultiScan for MASLD diagnosis: a real-world multi-national randomised clinical trial Communications Medicine Shumbayawonda et al. examine the impact of multi-parametric MRI in managing MASLD in a multinational randomised clinical trial. Findings show multi-parametric MRI is cost-effective reduces consultations and improves diagnostic rates compared to standard of care enhancing diagnostic accuracy and streamlining pathways without requiring additional resources" [X Link](https://www.nature.com/articles/s43856-025-00796-9) 2025-04-09T11:31Z 208.1M followers, [--] engagements "Relationship between adolescent anemia and school attendance observed during a nationally representative survey in India Communications Medicine De Neve et al. determine the relationship between anemia and school attendance among adolescents using a large national dataset from India. In this within-household analysis the relationship between anemia and schooling is more muted compared to more conventional analyses which do not account for all household-level factors" [X Link](https://www.nature.com/articles/s43856-024-00533-8) 2024-06-26T04:00Z [----] followers, [---] engagements "Demographic variation in pain across [--] countries Communications Medicine Macchia et al. use nationally representative data from [--] countries (N = 202898) and a random effects meta-analysis to examine the proportion of people in pain across key demographic groups. Findings show substantial variation in pain across these groups and countries" [X Link](https://www.nature.com/articles/s43856-025-00858-y) 2025-05-16T12:02Z 208.1M followers, [---] engagements "Long-term risk of malignancies in persons with ischemic heart disease treated with trimetazidine dihydrochloride Communications Medicine Cheng et al. explore the impact of trimetazidine an anti-ischemic agent that preferentially potentiates cellular glucose oxidation on cancer risk. Findings show an association of use with a reduced long-term risk of malignancies" [X Link](https://www.nature.com/articles/s43856-025-00805-x) 2025-04-16T11:32Z 208.1M followers, [--] engagements "Relationship between grammar and schizophrenia: a systematic review and meta-analysis Communications Medicine Elleuch et al perform a systematic review and meta-analysis to evaluate the association between grammatical impairments and schizophrenia. Large effect size deficits in grammatical comprehension and production occur in this illness highlighting the need for targeted interventions to address language use in people with psychotic disorders" [X Link](https://www.nature.com/articles/s43856-025-00944-1) 2025-06-16T13:20Z 208.1M followers, [---] engagements "Phase [--] dose expansion and biomarker study assessing first-in-class tumor microenvironment modulator VT1021 in patients with advanced solid tumors Communications Medicine Chen et al. report findings from a phase [--] dose expansion study of the tumor microenvironment modulator VT1021 in patients with solid tumors. VT1021 is found to be safe and tolerable with preliminary evidence of efficacy and biomarkers of response" [X Link](https://www.nature.com/articles/s43856-024-00520-z) 2024-05-30T17:00Z 208.1M followers, [---] engagements "Deep learning for video-based assessment of endotracheal intubation skills Communications Medicine Ainam et al. introduce a video-based system to assess endotracheal intubation (ETI) skills leveraging 2D and 1D convolutional models with a cross-view attention module to analyze complex patterns. The system effectively differentiates between experts and novices improving the objectivity and efficiency of ETI training and certification" [X Link](https://www.nature.com/articles/s43856-025-00776-z) 2025-05-05T11:31Z 208.1M followers, [--] engagements "Iron homeostasis and cytokine responses in Gabonese children with febrile illness Communications Medicine Mayr Ndong et al. investigate the interplay between anemia iron homeostasis and immune activation in a retrospective cross-sectional study of Gabonese children with acute febrile illness. Anemia rates are linked to inflammation and iron deficiency with pathogen-specific immune markers correlating with iron availability" [X Link](https://www.nature.com/articles/s43856-025-00988-3) 2025-08-03T02:22Z 208.1M followers, [--] engagements "Large-scale data reveal disparate associations between leisure time physical activity patterns and mental health Communications Medicine Zhou et al. analyze leisure time physical activity and self-reported mental health in people of different ages in China. Exercise is associated with better mental health even if exercise is of moderate intensity" [X Link](https://www.nature.com/articles/s43856-023-00399-2) 2024-01-08T10:00Z 208.1M followers, [--] engagements "Machine learning identifies risk factors associated with long-term sick leave following COVID-19 in Danish population Communications Medicine Jakobsen et al. analyze data from a cohort of [-----] individuals from Denmark with causal machine learning and identify age sex high BMI and depression as key factors for long-term sick leave following SARS-CoV-2 infection" [X Link](https://www.nature.com/articles/s43856-023-00423-5) 2024-01-22T09:00Z 208.1M followers, [---] engagements "SARS-CoV-2 dynamics in New York City during March 2020August [----] Communications Medicine Yang et al. utilize a model-inference system and multiple datasets to reconstruct the underlying SARS-CoV-2 transmission dynamics and validate the estimates using wastewater viral load data. This study estimates key epidemiological variables including infection rate and transmissibility for each variant and infection-fatality risk in New York City during March 2020August 2023" [X Link](https://www.nature.com/articles/s43856-025-00826-6) 2025-04-29T12:01Z 208.1M followers, [--] engagements "Preclinical evaluation of small molecule inhibitors as early intervention therapeutics against Russells viper envenoming in India Communications Medicine Rudresha et al. evaluated small molecule inhibitors as early intervention therapeutics against Russell’s viper (Daboia russelii) envenoming. Varespladib and marimastat effectively neutralise the toxicities of pan-Indian Daboia russelii venom in vitro and in vivo including with delayed treatment" [X Link](https://www.nature.com/articles/s43856-025-00900-z) 2025-06-13T07:02Z 208.1M followers, [--] engagements "Precision prognostics for cardiovascular disease in Type [--] diabetes: a systematic review and meta-analysis Communications Medicine Ahmad Lim Morieri Tam et al perform a systematic review and meta-analysis of biomarkers genetic markers and risk scores for prediction of cardiovascular outcomes in Type [--] diabetes. A few prognostic markers are identified that provide incremental predictive utility beyond established cardiovascular risk factors" [X Link](https://www.nature.com/articles/s43856-023-00429-z) 2024-01-31T08:00Z 208.1M followers, [---] engagements "A cross-sectional and population-based study from primary care on post-COVID-19 conditions in non-hospitalized patients Communications Medicine Ose et al. conduct a questionnaire-based survey of post COVID-19 condition (PCC) symptoms among primary care patients with and without a diagnosis of COVID-19. They find reporting of PCC symptoms highly prevalent in all patients and highlight the challenges of accurate diagnosis of PCC due to the overlap with non-COVID-related symptoms" [X Link](https://www.nature.com/articles/s43856-024-00440-y) 2024-02-26T12:00Z 208.1M followers, [---] engagements "The importance of funding and investment to strengthen data science in Africa Communications Medicine Kayalioglu et al. explore the underutilization of data science (DS) to improve health outcomes in Africa and advocate for increased strategic investment in DS infrastructure talent development and research funding. They highlight current challenges while proposing collaborative efforts to build sustainable locally driven DS growth across Africa" [X Link](https://www.nature.com/articles/s43856-025-01001-7) 2025-08-13T11:43Z 208.1M followers, [--] engagements "Generative deep learning furthers the understanding of local distributions of fat and muscle on body shape and health using 3D surface scans Communications Medicine Leong et al. develop a generative deep learning model that produces analyzable dual energy X-ray absorptiometry (DXA) scans from 3D body surface scans. Model-generated DXA scans are analyzed using clinical commercial software and yield accurate quantities of fat lean and bone mass for total body and body subregions" [X Link](https://www.nature.com/articles/s43856-024-00434-w) 2024-02-15T09:00Z [----] followers, [---] engagements "Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer Communications Medicine Cheng and Lama et al. developed a synergistic dual-modality AI framework for prediction of MMRd/MSI-High status in colorectal cancer and PD-L1 status in breast cancer. Their model which analyzes H&E and IHC images achieves clinical grade performance and identifies patients with improved outcomes on pembrolizumab immunotherapy" [X Link](https://www.nature.com/articles/s43856-025-01045-9) 2025-08-29T15:41Z 208.1M followers, [---] engagements "A cross-national analysis of demographic variation in self-rated mental health across [--] countries Communications Medicine Okafor et al. analyze survey responses from adults in [--] countries to explore differences by age gender education and other characteristics in their rating of their mental health. Self-rated mental health is generally higher in some African countries and among older adults men married individuals and frequent religious service attendees" [X Link](https://www.nature.com/articles/s43856-025-01038-8) 2025-09-01T11:41Z 208.1M followers, [---] engagements "Multi-scale V-net architecture with deep feature CRF layers for brain extraction Communications Medicine Park et al. improve a base segmentation model for brain extraction to increase robustness and go beyond the provided ground truth segmentation. Brain extraction improves when data is extracted from normal and clinical data using this model" [X Link](https://www.nature.com/articles/s43856-024-00452-8) 2024-02-27T11:00Z 208.1M followers, [---] engagements "Keratinocyte SR-B1 expression and targeting in cytokine-driven skin inflammation Communications Medicine Trujillo et al. identify scavenger receptor class B type I (SR-B1) as a keratinocyte marker of skin inflammation and a potential therapeutic target. Topically delivered HDL-like nanoparticles target SR-B1 reduce inflammatory signaling in keratinocytes and improve imiquimod-induced inflammation in murine models" [X Link](https://www.nature.com/articles/s43856-025-00804-y) 2025-04-28T12:02Z 208.1M followers, [--] engagements "Synthetic modified vaccinia Ankara vaccines confer cross-reactive and protective immunity against mpox virus Communications Medicine Chiuppesi et al. demonstrate that COVID-19 vaccine COH04S1 harboring a synthetic modified vaccinia Ankara-vector elicits cross-reactive responses against mpox virus (MPXV) similar to those induced by FDA-approved mpox vaccine JYNNEOS in healthy adults and non-human primates. COH04S1 also confers protective immunity against MPXV in a mouse model of mpox" [X Link](https://www.nature.com/articles/s43856-024-00443-9) 2024-02-21T13:00Z 208.1M followers, [---] engagements "Cardiologist-level interpretable knowledge-fused deep neural network for automatic arrhythmia diagnosis Communications Medicine Jin et al. develop a deep learning-based model for diagnosing arrhythmias based on a large-scale ECG dataset. The model demonstrates cardiologist-level accuracy and can potentially improve the efficiency and accuracy of ECG detection in remote and underdeveloped areas offering a promising prospect for telemedicine" [X Link](https://www.nature.com/articles/s43856-024-00464-4) 2024-03-01T12:00Z 208.1M followers, [---] engagements "Longitudinal study of risk factors predicting cannabis use disorder in UK young adults and adolescents Communications Medicine Skumlien et al. investigate whether eight factors predict cannabis use disorder in a 12-month longitudinal study. Adolescent age and baseline cannabis use disorder but not gender cannabis use frequency alcohol use tobacco use negative life events or the COVID-19 lockdown are associated with more severe cannabis use disorder at follow-up" [X Link](https://www.nature.com/articles/s43856-025-01018-y) 2025-08-14T11:45Z 208.1M followers, [---] engagements "Effects of short-term moderate intensity exercise on the serum metabolome in older adults: a pilot randomized controlled trial Communications Medicine Wong et al. conduct a pilot randomized controlled trial on the effects of twelve weeks of exercise on the serum metabolome in older adults. The authors identify changes in metabolites related to mitochondrial fuel oxidation and amino acid pathways and relate these to imaging markers of cardiac aging in post-hoc analyses" [X Link](https://www.nature.com/articles/s43856-024-00507-w) 2024-06-03T05:00Z 208.1M followers, [---] engagements "Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal Communications Medicine Baird et al model opioid overdose and naloxone administration in a whole-body physiology model. The derived total naloxone rescue doses obtained are much higher than the current suggested guidelines" [X Link](https://www.nature.com/articles/s43856-024-00536-5) 2024-06-25T16:00Z 208.1M followers, [---] engagements "Adverse childhood experiences increase the long-term accumulation of morbidity in women Communications Medicine Rocca et al. examine the effect of early-life adverse experiences including early adulthood on late-life morbidity using a cohort study in the US. The authors show that both adverse childhood experiences and abuse in childhood or early adulthood are associated with an accelerated accumulation of morbidity later in life" [X Link](https://www.nature.com/articles/s43856-025-00961-0) 2025-08-01T12:31Z 208.1M followers, [--] engagements "Prioritizing mental health support for physician-scientist trainees Communications Medicine Tuazon et al. highlight the mental health challenges facing physician-scientist trainees who have a dual commitment to advancing clinical care and undertaking research. The authors outline the critical gaps in mental health support structures available to this unique trainee population and provide recommendations to redress the concerns discussed" [X Link](https://www.nature.com/articles/s43856-025-00843-5) 2025-05-12T12:31Z 208.1M followers, [--] engagements "Generative deep learning for the development of a type [--] diabetes simulator Communications Medicine Mujahid et al. develop a type [--] diabetes patient simulator using a conditional sequence-to-sequence deep generative model. Their approach captures causal relationships between insulin carbohydrates and blood glucose levels producing virtual patients with similar responses to real patients in open and closed-loop insulin therapy scenarios" [X Link](https://www.nature.com/articles/s43856-024-00476-0) 2024-03-27T16:00Z 208.1M followers, [--] engagements "Tethered spinal cord tension assessed via ultrasound elastography in computational and intraoperative human studies Communications Medicine Kerensky et al. quantify tension across human spinal cords in computational simulations a cadaveric benchtop model and a neurosurgical case series. Their direct methodology successfully differentiates stretched spinal cords from healthy states in all sub-studies" [X Link](https://www.nature.com/articles/s43856-023-00430-6) 2024-01-10T17:00Z [----] followers, [--] engagements "Real-world impact of physical activity reward-driven digital app use on cardiometabolic and cardiovascular disease incidence Communications Medicine Senderey et al. examine the real-world impact of a reward-driven physical activity app on cardiometabolic and cardiovascular disease incidence using electronic health records from Israel’s largest healthcare organization. App users have a lower risk of developing cardiovascular disease stroke and type [--] diabetes" [X Link](https://www.nature.com/articles/s43856-025-00792-z) 2025-04-17T11:02Z 208.1M followers, [--] engagements "Mediation of the association between disadvantaged neighborhoods and cortical microstructure by body mass index - Communications Medicine Kilpatrick et al. investigate the relationship between neighborhood disadvantage trans-fatty acid intake body mass index stress and cortical microstructure. Results suggest obesogenic aspects of neighborhood disadvantage could disrupt information processing flexibility in regions involved in reward emotion regulation and cognition" [X Link](https://www.nature.com/articles/s43856-023-00350-5) 2023-09-15T00:00Z [----] followers, 15.9K engagements "Predicting future hospital antimicrobial resistance prevalence using machine learning Communications Medicine Vihta et al. use past hospital data including bloodstream infection cases susceptibilities and antimicrobial use to predict future resistance prevalence. Machine learning can improve the accuracy of predictions potentially impacting interventions" [X Link](https://www.nature.com/articles/s43856-024-00606-8) 2024-10-17T10:32Z 208.1M followers, [---] engagements "Independent transcriptional patterns reveal biological processes associated with disease-free survival in early colorectal cancer Communications Medicine Knapen et al. apply consensus-independent transcriptional component analysis to dissect transcriptomes into statistically independent transcriptional components in early colorectal cancer. Their findings identify [--] biological processes associated with disease-free survival which enables stratification of patients into different subgroups" [X Link](https://www.nature.com/articles/s43856-024-00504-z) 2024-06-02T13:00Z 208.1M followers, [---] engagements "High diversity of Escherichia coli causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach Communications Medicine Pearse et al. use whole genome sequencing to describe the antigenic and overall diversity of [---] Escherichia coli isolates causing invasive infections in neonates in a single hospital in Malawi. High levels of O-antigen diversity are found highlighting the difficulty of developing a vaccine for this patient population" [X Link](https://www.nature.com/articles/s43856-025-01007-1) 2025-08-12T11:42Z 208.1M followers, [--] engagements "AAV9-cBIN1 gene therapy rescues chronic heart failure due to ischemic cardiomyopathy in a canine model Communications Medicine Khan et al. perform AAV9-cBIN1 gene therapy in a canine model of acquired chronic ischemic cardiomyopathy. They show AAV9-cBIN1 therapy mitigates disease progression and can reverse heart failure in this model" [X Link](https://www.nature.com/articles/s43856-025-00787-w) 2025-04-21T12:31Z 208.1M followers, [---] engagements "Mendelian randomization reveals interactions of the blood proteome and immunome in mitral valve prolapse Communications Medicine Moncla et al. scrutinize the role of circulating proteome in mitral valve prolapse development. Integration conducted on large-scale cross-modality data uncover a causal role of the circulating proteome immunome and macrophage M2 polarization in mitral valve prolapse" [X Link](https://www.nature.com/articles/s43856-024-00530-x) 2024-06-21T11:00Z 208.1M followers, [---] engagements "S100A8/A9 predicts response to PIM kinase and PD-1/PD-L1 inhibition in triple-negative breast cancer mouse models Communications Medicine Begg et al. show that S100A8/9 expression is associated with risk of progression in early-stage triple-negative breast cancer cohorts. Using a small inhibitor screen the authors identify PIM kinase inhibitors to target S100A8/A9 expression improving antitumor response when combined with immune checkpoint blockade in mice" [X Link](https://www.nature.com/articles/s43856-024-00444-8) 2024-02-26T08:00Z 208.1M followers, [---] engagements "Obstructive sleep apnea severity varies by season and environmental influences such as ambient temperature Communications Medicine Lechat et al. examines the severity of obstructive sleep apnea (OSA) using a large global dataset of users of an FDA-validated under-the-mattress sensor. These results demonstrate a seasonal component in the severity of OSA and show that this effect is partially explained by ambient temperature and variations in sleep duration" [X Link](https://www.nature.com/articles/s43856-025-01016-0) 2025-08-21T12:41Z 208.1M followers, [--] engagements "Utility of smart watches for identifying arrhythmias in children Communications Medicine Zahedivash et al. undertake a single center retrospective analysis of patients less than [--] years of age with history of an arrhythmia to determine whether a wearable device can capture arrhythmias. Arrhythmias are identified in 28% of patients mainly the difficult to identify supraventricular tachycardias" [X Link](https://www.nature.com/articles/s43856-023-00392-9) 2024-01-10T09:00Z 208.1M followers, [--] engagements "18FFluorThanatrace PET imaging as a biomarker of response to PARP inhibitors in breast cancer Communications Medicine Gitto Pantel et al. evaluate a PARP-targeted PET imaging ligand 18 FFlourThanatrace as a biomarker of response to PARP inhibitors in patients with breast cancer. There is 18 FFlourThanatrace uptake in the tumor before treatment and a decline in uptake after PARP inhibitor therapy initiation correlating with patient progression free survival" [X Link](https://www.nature.com/articles/s43856-025-00791-0) 2025-04-15T11:32Z 208.1M followers, [--] engagements "Assessing regional variations and sociodemographic barriers in the progress toward UNAIDS 95-95-95 targets in Zimbabwe Communications Medicine Chowdhury et al. conducted a geospatial analysis to identify distinct regional patterns in progress toward the 95-95-95 HIV care targets in Zimbabwe. They reveal local areas with specific care needs highlighting significant spatial disparities and the influence of socio-demographic factors on gaps in achieving these targets" [X Link](https://www.nature.com/articles/s43856-025-00824-8) 2025-05-01T11:15Z 208.1M followers, [--] engagements "Proteome profiling of home-sampled dried blood spots reveals proteins of SARS-CoV-2 infections Communications Medicine Fredolini et al. present a proteomics analysis of home-sampled dried blood spots taken from the general population in Stockholm during the COVID-19 pandemic. The study provides insights into the molecular effects of SARS-CoV-2 infection in non-hospitalized individuals and demonstrates the compatibility of self-sampled blood spots with proteomics" [X Link](https://www.nature.com/articles/s43856-024-00480-4) 2024-05-03T17:00Z 208.1M followers, [---] engagements "Increased testing is needed for Mpox in DR Congo to urgently curb disease spread Communications Medicine Imani-Musimwa et al. describe the precarious situation in the DRC exacerbated by armed conflict poor infrastructure and limited healthcare resources and call for urgent action to enhance Mpox testing and control efforts which could significantly reduce the outbreak’s impact and improve health security in Africa" [X Link](https://www.nature.com/articles/s43856-025-00813-x) 2025-07-24T14:49Z 208.1M followers, [---] engagements "Early elevated IFN is a key mediator of HIV pathogenesis Communications Medicine Le Buanec et al. compared distribution and frequency of cell markers associated with immune dysfunction between HIV elite controllers (EC) and untreated non-EC. They demonstrate that untreated HIV-infected individuals exhibit structurally and functionally impaired immune subsets as a consequence of excessive levels of serum IFNα" [X Link](https://www.nature.com/articles/s43856-024-00454-6) 2024-05-03T06:30Z 208.1M followers, [---] engagements "UK Biobank data demonstrate long-term exposure to floods is a risk factor for incident dementia Communications Medicine Wu et al. investigate the association between flooding exposure and incident dementia using conditional logistic regression models. Flooding exposure is linked to an elevated risk of incident dementia with significant variations observed across age groups and between sexes" [X Link](https://www.nature.com/articles/s43856-025-00771-4) 2025-04-08T11:01Z 208.1M followers, [--] engagements "Super-resolution neural networks improve the spatiotemporal resolution of adaptive MRI-guided radiation therapy Communications Medicine Grover et al. describe the training deployment and evaluation of real-time super-resolution imaging for MRI-guided radiation therapy. Volunteer phantom and simulation experiments demonstrate that super-resolution can increase the spatiotemporal resolution of real-time MRI guidance" [X Link](https://www.nature.com/articles/s43856-024-00489-9) 2024-04-10T08:00Z 208.1M followers, [---] engagements "Implementing health economics for pharmacogenomics research translation in Africa Communications Medicine Alimohamed et al. outline the current pharmacogenomics landscape in Africa. They explore the role of health economics in its clinical translation and propose context-sensitive strategies for equitable implementation across the continent" [X Link](https://www.nature.com/articles/s43856-025-00955-y) 2025-07-05T12:01Z 208.1M followers, [---] engagements "Multi-model assurance analysis showing large language models are highly vulnerable to adversarial hallucination attacks during clinical decision support Communications Medicine Omar et al. test six leading large language models with [---] doctor-designed clinical vignettes containing a single fake lab value sign or disease. They show that the models repeat or elaborate on the planted error in up to [--] % of cases with a simple mitigation prompt halving the rate but not eliminating the risk" [X Link](https://www.nature.com/articles/s43856-025-01021-3) 2025-09-30T16:49Z 2.1M followers, [----] engagements "Forecasting influenza hospital admissions within English sub-regions using hierarchical generalised additive models Communications Medicine Mellor et al. introduce a new method for forecasting hospital admissions with seasonal influenza in a resurgent season that can be used to inform policy makers. The developed generalized additive model shows improved performance over other time series approaches when scored using probabilistic methods" [X Link](https://www.nature.com/articles/s43856-023-00424-4) 2024-01-23T14:00Z 208.1M followers, [--] engagements "Molecular analysis for ovarian cancer detection in patient-friendly samples Communications Medicine Wever et al. explore the use of different types of patient-friendly material including urine for the detection of ovarian cancer by methylation and copy number analysis. Upon continued development DNA-based testing in cervical scrapes and urine could aid ovarian cancer diagnosis" [X Link](https://www.nature.com/articles/s43856-024-00517-8) 2024-05-20T15:00Z 208.1M followers, [---] engagements "Optimal timing for atrial fibrillation patients to undergo catheter ablation Communications Medicine Lin et al. investigate the impact of diagnosis-to-ablation timing on atrial fibrillation (AF) recurrence after catheter ablation. This study finds that early catheter ablation characterized as diagnosis-to-ablation in less than [--] years is preferable for maintaining sinus rhythm particularly in persistent AF" [X Link](https://www.nature.com/articles/s43856-025-00960-1) 2025-07-10T11:31Z 208.1M followers, [--] engagements "Improvements induced by retinal gene therapy with voretigene neparvovec depend on visual cortical hemispheric dominance mechanisms Communications Medicine Ferreira M et al. investigate the cortical response to visual function restoration in [--] patients with RPE65-RD treated with voretigene neparvovec using psychophysical and neuroimaging methods. The authors found significant improvements in light sensitivity and neural response under low luminance conditions particularly in the right hemisphere" [X Link](https://www.nature.com/articles/s43856-025-00820-y) 2025-04-30T12:31Z 208.1M followers, [--] engagements "Rapamycin treatment for Alzheimers disease and related dementias: a pilot phase [--] clinical trial Communications Medicine Gonzales et al. conducted an open-label phase [--] clinical trial of rapamycin for mild cognitive impairment and dementia due to Alzheimer’s disease. Rapamycin is not detected in cerebrospinal fluid before or after treatment but there are changes in multiple neurodegenerative diseases and inflammatory biomarkers from baseline to post-treatment" [X Link](https://www.nature.com/articles/s43856-025-00904-9) 2025-05-22T23:40Z 208.1M followers, [---] engagements "Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology Communications Medicine Ewart et al. assess the performance of a human Liver-Chip for predictive toxicology. They also perform an economic analysis to demonstrate its potential financial value for the pharmaceutical industry" [X Link](https://www.nature.com/articles/s43856-022-00209-1) 2025-08-27T19:14Z 208.1M followers, [--] engagements "Digital twin simulation modelling shows that mass testing and local lockdowns effectively controlled COVID-19 in Denmark - Communications Medicine Grsbll et al. use a detailed individual-based simulation model of SARS-CoV-2 transmission to evaluate mass testing and local lockdowns during the Alpha wave in Denmark in counterfactual scenarios. The model predicts that the combination of these measures prevented a large increase in hospitalizations while increasing overall societal freedom" [X Link](https://www.nature.com/articles/s43856-024-00621-9) 2024-10-04T00:00Z 208.1M followers, [--] engagements "A phase IIb randomized placebo-controlled trial testing the effect of MAG-EPA long-chain omega-3 fatty acid dietary supplement on prostate cancer proliferation Communications Medicine Robitaille et al. report findings from a phase IIb randomized placebo-controlled trial evaluating the effect of a long-chain omega-3 fatty acid MAG-EPA dietary supplement on prostate cancer proliferation. The dietary supplement had no effect on the primary outcome of prostate cancer proliferation according to Ki-67 expression" [X Link](https://www.nature.com/articles/s43856-024-00456-4) 2024-03-28T08:00Z 208.1M followers, [---] engagements "A comprehensive AI model development framework for consistent Gleason grading Communications Medicine Huo Ong et al. present a comprehensive workflow to try to overcome key limitations in prior approaches for artificial intelligence (AI)-assisted prostate cancer Gleason grading. Their approach incorporates automated quality control efficient annotation and visualization and pathologist-AI interaction" [X Link](https://www.nature.com/articles/s43856-024-00502-1) 2024-06-04T19:00Z 208.1M followers, [---] engagements "Community-based screening enhances hepatitis B virus linkage to care among West African migrants in Spain Communications Medicine Picchio et al. report findings from a community-based hepatitis B virus (HBV) screening program for sub-Saharan African migrants in Catalonia Spain utilizing simplified testing and expedited referral to specialist care. Their findings support the adoption of these strategies to increase HBV testing and linkage to care among at-risk populations" [X Link](https://www.nature.com/articles/s43856-023-00420-8) 2024-01-15T08:00Z 208.1M followers, [---] engagements "A 24-month National Cohort Study examining long-term effects of COVID-19 in children and young people Communications Medicine Stephenson Pinto Pereira et al. investigate the proportion of children and young people with Post Covid-19 condition 24-months post-infection. Only 7.2% meet the definition consistently at 3- 6- 12- and 24-months post-infection highlighting the importance of longitudinal studies" [X Link](https://www.nature.com/articles/s43856-024-00657-x) 2024-12-08T11:30Z 208.1M followers, [---] engagements "Inhibiting anti-angiogenic VEGF165b activates a miR-17-20a-Calcipressin-3 pathway that revascularizes ischemic muscle in peripheral artery disease Communications Medicine Batan et al. show that inhibiting the antiangiogenic VEGF165b isoform activates a previously unrecognized miR-17-20a-RCAN3 pathway that induces ischemic endothelial cell angiogenic capacity and promotes M2-like macrophage polarization to achieve perfusion recovery in murine peripheral artery disease (PAD) model" [X Link](https://www.nature.com/articles/s43856-023-00431-5) 2024-02-16T12:00Z 208.1M followers, [--] engagements "Evaluating variant pathogenicity prediction tools to establish African inclusive guidelines for germline genetic testing Communications Medicine Zhou et al. evaluate the predictive performance of [--] variant pathogenicity prediction tools using genomic data of advanced prostate cancer. MetaSVM CADD and Eigen-raw provide strong performance across ancestries while others like MutationTaster and DANN were African-specific with lower sensitivity for African data" [X Link](https://www.nature.com/articles/s43856-025-00883-x) 2025-05-19T22:15Z 208.1M followers, [--] engagements "AAV9:PKP2 improves heart function and survival in a Pkp2-deficient mouse model of arrhythmogenic right ventricular cardiomyopathy Communications Medicine Wu Zeng et al. assess the feasibility and efficacy of AAV9:PKP2 gene therapy in the Pkp2-cKO mouse model of arrhythmogenic right ventricular cardiomyopathy. They show that it ameliorates ventricular arrhythmias reverses adverse right ventricular remodeling improves heart function and reduces mortality in this mouse model" [X Link](https://www.nature.com/articles/s43856-024-00450-w) 2024-03-26T14:00Z 208.1M followers, [---] engagements "Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes Communications Medicine Hirose et al. demonstrate a genome editing-based strategy to treat obesity and pre-diabetes complex diseases without a defined genetic cause. A single in vivo knock-in of a secretion-engineered Exendin-4 gene into the liver enables sustained peptide release reducing body weight and improving glucose metabolism in mice" [X Link](https://www.nature.com/articles/s43856-025-00959-8) 2025-07-13T19:12Z 208.1M followers, [---] engagements "Carotid body dysregulation contributes to Long COVID symptoms Communications Medicine El-Medany Adams Blythe et al. Investigate whether the carotid chemoreflex could be a mechanism underlying unexplained breathlessness in non-hospitalised patients with long COVID. Results show that carotid chemoreflex is sensitised in patients with long COVID and may explain dysregulated breathing and exercise intolerance in these participants" [X Link](https://www.nature.com/articles/s43856-024-00447-5) 2024-02-20T16:00Z 208.1M followers, [---] engagements "Phenotypic and genomic characteristics of clinical IMP-producing Klebsiella spp. Isolates in China Communications Medicine Liu et al. analyze phenotypic and genomic characteristics of clinical IMP-producing Klebsiella spp. Isolates in China. Multi-clonal transmission multiple genetic environments and differing plasmid types all play a role in disseminating blaIMP genes among Klebsiella spp" [X Link](https://www.nature.com/articles/s43856-024-00439-5) 2024-02-27T07:00Z 208.1M followers, [---] engagements "Low-calorie diets for people with isolated impaired fasting glucose Communications Medicine Thirunavukkarasu et al. discuss how standard lifestyle interventions prove ineffective in preventing type [--] diabetes in individuals with isolated impaired fasting glucose a highly prevalent prediabetes phenotype globally. They propose low-calorie diets as a promising strategy for diabetes prevention in this high-risk population" [X Link](https://www.nature.com/articles/s43856-024-00466-2) 2024-03-04T16:00Z 208.1M followers, [---] engagements "A diffusion model for universal medical image enhancement Communications Medicine Fei Li Yang Gao et al. present UniMIE a training-free diffusion model for universal medical image enhancement without fine-tuning. It achieves high-quality results across [--] modalities and 15+ medical types using one ImageNet pre-trained model" [X Link](https://www.nature.com/articles/s43856-025-00998-1) 2025-08-08T11:37Z 208.1M followers, [--] engagements "Machine learning-assisted assessment of extracellular vesicles can monitor cellular rejection after heart transplant Communications Medicine Burrello et al. combine extracellular vesicle profiling with adaptive artificial intelligence to monitor cell rejection after heart transplant. Heart transplant rejection is detected with high accuracy outperforming biopsy and anticipating rejection before histological signs offering a promising noninvasive tool for timely intervention and personalized monitoring" [X Link](https://www.nature.com/articles/s43856-025-00999-0) 2025-08-07T16:35Z 208.1M followers, [--] engagements "Childhood predictors of suffering in adulthood across [--] countries Communications Medicine Cowden et al. use nationally representative data from [--] countries included in Wave [--] of the Global Flourishing Study to explore associations of individual characteristics and retrospectively recalled childhood factors with suffering in adulthood. A combination of risk and protective factors during childhood may be associated with suffering in adulthood" [X Link](https://www.nature.com/articles/s43856-025-00913-8) 2025-06-25T12:02Z 208.1M followers, [--] engagements "A multidimensional network of factors associated with long COVID in the French population Communications Medicine Coste et al. survey factors potentially associated with long COVID in [----] adults in France. A broad spectrum of medical psychological and social factors are found to be associated with an increased risk of developing long COVID" [X Link](https://www.nature.com/articles/s43856-025-00846-2) 2025-04-14T12:23Z 208.1M followers, [--] engagements "Considering clonal hematopoiesis of indeterminate potential in space radiation risk analysis for hematologic cancers and cardiovascular disease Communications Medicine Werneth et al. evaluate the impact of clonal hematopoiesis of indeterminate potential (CHIP) on health risks associated with space radiation exposures in astronauts. This work highlights the importance of considering personalized risk factors such as CHIP for effective risk assessment and monitoring of astronaut health" [X Link](https://www.nature.com/articles/s43856-023-00408-4) 2024-06-20T14:00Z 208.1M followers, [---] engagements "Detection of COVID-19 features in lung ultrasound images using deep neural networks Communications Medicine Zhao et al. investigate optimal strategies to detect COVID-19 features in lung ultrasound images using deep neural networks trained with simulated and in vivo datasets. Including simulated data during training improves detection performance and training efficiency and is a promising alternative to curating thousands of patient images" [X Link](https://www.nature.com/articles/s43856-024-00463-5) 2024-03-13T17:00Z 208.1M followers, [---] engagements "Generalisable deep learning method for mammographic density prediction across imaging techniques and self-reported race Communications Medicine Khara et al perform a comprehensive performance analysis for a deep learning breast density prediction model using a large scale racially diverse dataset. They find that the model generalises across imaging techniques and self-reported race providing assurances for the safe and ethical use of automated breast density prediction" [X Link](https://www.nature.com/articles/s43856-024-00446-6) 2024-02-20T12:00Z 208.1M followers, [---] engagements "Feasibility of serial measurement of nitrite for pharmacodynamic monitoring and precision prescribing in urinary tract infections Communications Medicine Stadler et al. evaluate the diagnostic value of urinary tract infection biomarker nitrite in predicting disease progression and treatment efficacy. The longitudinal measurement of nitrite in an in-vitro UTI distinguishes between amoxicillin-resistant and susceptible E. coli strains and correlates with bacterial colony-forming unit counts in-vitro and in clinical UTI" [X Link](https://www.nature.com/articles/s43856-025-00969-6) 2025-07-29T11:31Z 208.1M followers, [---] engagements "Concurrent gliomas in patients with multiple sclerosis Communications Medicine Sahm et al. evaluate clinical imaging and molecular data from a small cohort of patients with concurrent multiple sclerosis (MS) and gliomas. They report differential methylation of some immune-related loci in tumors from patients with MS and that inflammatory disease activity can increase in these patients after brain tumor radiotherapy" [X Link](https://www.nature.com/articles/s43856-023-00381-y) 2024-01-17T17:00Z 208.1M followers, [---] engagements "N-glycan-modified -L-iduronidase produced by transgenic silkworms ameliorates clinical signs in a Japanese macaque with mucopolysaccharidosis I Communications Medicine Shinoda and Kitakaze et al. prepared recombinant hIDUA from transgenic silkworm cocoons and transglycosylated to mannose-6-phosphate- or α26-sialyl glycan-type using ENGases. These enzymes were administrated to a mucopolysaccharidosis type I macaque and succeeded in improving the clinical signs and reducing the urinary glycosaminoglycan levels" [X Link](https://www.nature.com/articles/s43856-025-00841-7) 2025-05-08T12:32Z 208.1M followers, [---] engagements "Household-level effects of seasonal malaria chemoprevention in the Gambia Communications Medicine Soremekun et al. report the impact of extending seasonal malaria chemoprevention (SMC) to children aged [--] years on malaria transmission in the context of a national routine programme. This SMC extension to older children reduces the risk of clinical malaria and asymptomatic infection among adolescents and adults within the same household" [X Link](https://www.nature.com/articles/s43856-024-00503-0) 2024-05-31T15:00Z [----] followers, [---] engagements "A bibliometric analysis of the gender gap in the authorship of leading medical journals Communications Medicine Brück observes a decrease in the gender gap in the authorship of leading medical journals between [----] and [----] with some country-specific variation. This study provides a model approach for tracking gender representation in academic research" [X Link](https://www.nature.com/articles/s43856-023-00417-3) 2024-01-09T12:00Z 208.1M followers, [--] engagements "Altered mitochondrial function in fibroblast cell lines derived from disease carriers of spinal muscular atrophy Communications Medicine James et al. compare mitochondrial function in fibroblast cell lines from disease carriers of spinal muscular atrophy (SMA) and control individuals. They report altered mitochondrial activity in SMA carriers suggesting that carriers have a subclinical mitochondrial phenotype" [X Link](https://www.nature.com/articles/s43856-024-00515-w) 2024-05-20T10:30Z 208.1M followers, [---] engagements "A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism Communications Medicine Ptacin et al. utilize a semi-synthetic microbial platform with an expanded genetic code to discover a PEGylated IL-2 compound that stimulates Tregs with minimal effects on effector populations. Studies in mice and primates demonstrate Treg stimulation and support development of this compound for the potential treatment of autoimmune diseases" [X Link](https://www.nature.com/articles/s43856-024-00485-z) 2024-04-08T14:00Z 228.6M followers, [----] engagements "Substantial but spatially heterogeneous progress in male circumcision for HIV prevention in South Africa Communications Medicine Thomas et al. present a model that integrates household survey and health system data to estimate subnational circumcision coverage in South Africa during scale-up for HIV prevention. Results show considerable but heterogenous progress towards increasing circumcision coverage identifying priority ages and districts to reach national targets" [X Link](https://www.nature.com/articles/s43856-023-00405-7) 2024-02-02T07:00Z 208.1M followers, [---] engagements "A roadmap for genome projects to foster psychosocial and economic evidence to further policy and practice Communications Medicine Chung et al. examine the multi-dimensional effectiveness of genome sequencing and summarise indicators and measurement tools for psychosocial and economic outcomes. They highlight priority areas for outcome-oriented research and showcase best practices in selecting outcome measures for effective implementation within genome projects" [X Link](https://www.nature.com/articles/s43856-025-00917-4) 2025-06-18T09:01Z 208.1M followers, [---] engagements "Comprehensive testing of large language models for extraction of structured data in pathology Communications Medicine Grothey et al. examine the performance of large language models in structuring pathology reports. Findings demonstrate similar accuracy between commercial and open-source models providing a cost-effective privacy-conscious solution to extract structured data with high precision from bilingual datasets" [X Link](https://www.nature.com/articles/s43856-025-00808-8) 2025-04-23T12:01Z 208.1M followers, [--] engagements "Serum autotaxin is a prognostic indicator of liver-related events in patients with non-alcoholic fatty liver disease Communications Medicine Iwadare et al. investigate the value of serum autotaxin levels in predicting liver-related events within a retrospective cohort of [---] biopsy-proven NAFLD patients. Multivariate Cox proportional hazards models identify autotaxin levels and advanced fibrosis as independent predictive factors" [X Link](https://www.nature.com/articles/s43856-024-00499-7) 2024-05-14T07:00Z 208.1M followers, [---] engagements "Evaluation of a large language model to simplify discharge summaries and provide cardiological lifestyle recommendations Communications Medicine Rust et al. evaluate a large language model to simplify cardiology discharge summaries and provide lifestyle recommendations. Findings show improved readability while maintaining medical accuracy as well as relevant but not sufficiently personalized lifestyle recommendations" [X Link](https://www.nature.com/articles/s43856-025-00927-2) 2025-06-23T12:31Z 208.1M followers, [--] engagements Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing
@CommsMedicine Communications Medicine
Communications Medicine posts on X about countries, health, people with, vivo the most. They currently have [-----] followers and [---] posts still getting attention that total [---] engagements in the last [--] hours.
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Social Influence
Social category influence countries technology brands finance travel destinations stocks musicians currencies
Social topic influence countries, health, people with, vivo, india, prediction, is a, meta, events, multi
Top accounts mentioned or mentioned by @naturecomms @scireports @commspsychol @vigeotx @jingwatnick @naturemedicine @commsbio @commseng @fionakolbinger @jnkath @googlehealth @jhubme @hopkinsengineer @nesmathioudakis @abrarah84 @leelinglim1 @mariolucam @drronaldma1 @endohopkins @maria1969gomez
Top assets mentioned Alphabet Inc Class A (GOOGL)
Top Social Posts
Top posts by engagements in the last [--] hours
"Machine-learning of medical cannabis chemical profiles reveals analgesia beyond placebo expectations Communications Medicine Hatav et al. use machine learning to analyze chemical profiles of medical cannabis cultivars and their association to pain relief outcomes. Authors find that specific terpenoids predict pain relief outcomes in people with chronic pain providing evidence for compound-specific therapeutic effects beyond placebo responses"
X Link 2025-08-09T11:40Z 208.1M followers, [---] engagements
"Approaches to ensure an equitable and fair admissions process for medical training Communications Medicine Anachebe et al. discuss how to center equity in medical school admissions by presenting an equity-based framework that focuses on recruiting standards selection and support. Their recommended strategies are universally applicable across training programs and are accompanied by a number of promising examples"
X Link 2025-04-15T12:01Z 208.1M followers, [--] engagements
"Achieving inclusive healthcare through integrating education and research with AI and personalized curricula Communications Medicine Bahmani Cha Alavi Dixit et al. evaluate an AI-facilitated precision medicine learning platform they built Stanford Data Ocean. The platform which provided [----] costfree certification accesses across [--] countries demonstrates positive training outcomes across bioinformatics topics for low and middle income learners"
X Link 2025-09-03T09:14Z 228.6M followers, [---] engagements
"Visceral adipose tissue and hepatic fat as determinants of carotid atherosclerosis Communications Medicine de Souza et al. examine whether visceral adipose tissue (VAT) and hepatic fat (HF) are related to carotid atherosclerosis beyond traditional cardiovascular risk factors. Findings reveal that higher VAT and HF are linked to cardiovascular risks such as hypertension diabetes and high cholesterol as well as increased carotid atherosclerosis"
X Link 2025-10-19T15:12Z 208.1M followers, [--] engagements
"Computational pathology identifies immune-mediated collagen disruption to predict clinical outcomes in gynecologic malignancies Communications Medicine Aggarwal et al. develop a computational pathology tool to quantitatively characterize the immune-collagen relationship in gynecological cancers. The tool enables the prognostic stratification of patients and provides insights into the biology of the tumor microenvironment"
X Link 2024-01-23T07:00Z 208.1M followers, [---] engagements
"Reporting guidelines in medical artificial intelligence: a systematic review and meta-analysis Communications Medicine Kolbinger Veldhuizen et al. systematically review reporting guidelines for artificial intelligence (AI) methods in clinical research. They identify several essential commonly recommended items on study design and model performance while other items are specific to particular fields and research stages"
X Link 2024-04-15T15:30Z 208.1M followers, [---] engagements
"Associations between skeletal muscle strength and chronic kidney disease in patients with MASLD Communications Medicine Zhang and Gu used four cohorts to examine associations between skeletal muscle strength (SMS) and chronic kidney disease (CKD) in people with metabolic dysfunction-associated steatotic liver disease (MASLD). Higher handgrip/muscle strength is closely associated with a lower prevalence and incidence of CKD in people with MASLD"
X Link 2025-05-06T11:31Z 208.1M followers, [--] engagements
"Parasagittal dural volume correlates with cerebrospinal fluid volume and developmental delay in children with autism spectrum disorder - Communications Medicine Agarwal et al. apply a semi-supervised 2D U-Net to extract the volume of parasagittal dura in young kids with autism spectrum disorder. Positive correlation with cerebrospinal fluid volume and a negative correlation with severity of developmental delay suggests perturbed fluid dynamics"
X Link 2024-10-04T00:00Z 208.1M followers, [---] engagements
"First-in-human phase I dose escalation trial of the first-in-class tumor microenvironment modulator VT1021 in advanced solid tumors Communications Medicine Mahalingam et al. report findings from a first-in-human dose escalation study of the tumor microenvironment modulator VT1021 in patients with advanced solid tumors. VT1021 is found to be safe and well tolerated and the recommended phase II dose is established based on pharmacokinetic/dynamic properties and preliminary clinical activities"
X Link 2024-02-06T13:00Z 208.1M followers, [---] engagements
"Efficacy of monoclonal antibodies and maternal vaccination for prophylaxis of respiratory syncytial virus disease Communications Medicine Plock et al. integrate clinical efficacy data on monoclonal antibodies and maternal vaccination for prevention of RSV disease in infants. Monoclonal antibodies are predicted to be more efficacious than maternal vaccination in preterm and full-term infants with maternal vaccination expected to partially protect full-term infants born just before or during an RSV season"
X Link 2025-05-06T11:01Z 208.1M followers, [--] engagements
"Mini-GRID therapy delivers optimised spatially fractionated radiation therapy using a flattening free filter accelerator Communications Medicine Acuña et al. develop mini-GRID to optimally deliver spatially fractionated radiation therapy using a flattening filter-free linear accelerator. Authors demonstrate its feasibility and reduction in side effects on normal tissues through longitudinal MRI imaging behavioural tests histopathology and infrared microspectroscopy in rat brain tissue"
X Link 2025-04-29T11:01Z 208.1M followers, [--] engagements
"Multidimensional sleep profiles via machine learning and risk of dementia and cardiovascular disease Communications Medicine Cavaillès et al. identify three sleep/circadian profiles in older men and examine their links to health outcomes. Compared to the Active Healthy Sleepers group the Fragmented Poor Sleepers group shows higher risks of dementia and cardiovascular disease (CVD) while the Long and Frequent Nappers group shows a trend toward increased CVD risk only"
X Link 2025-08-18T11:31Z 208.1M followers, [---] engagements
"Deep learning analysis of epicardial adipose tissue to predict cardiovascular risk in heavy smokers Communications Medicine Foldyna et al. demonstrate that deep learning-based quantification of epicardial adipose tissue from low-dose chest CT scans independently predicts all-cause and cardiovascular mortality in heavy smokers. This can enhance cardiovascular risk stratification beyond traditional measures"
X Link 2024-03-26T19:00Z 208.1M followers, [---] engagements
"Development and multicenter validation of on-site breast cancer diagnosis using paper spray ionization miniature mass spectrometry Communications Medicine Huang Chung et al. develop the MiniMaP platform a miniature mass spectrometer coupled with paper spray ionization enabling rapid breast cancer diagnosis from core needle biopsy samples. The machine learning model trained on molecular profiles maintains consistent accuracy in multi centre validation"
X Link 2025-07-20T14:44Z 208.1M followers, [--] engagements
"Application of simultaneous uncertainty quantification and segmentation for oropharyngeal cancer use-case with Bayesian deep learning Communications Medicine Sahlsten et al. systematically evaluate two Bayesian deep learning methods and eight uncertainty measures for the segmentation of oropharyngeal cancer primary gross tumor volume with a multi-institute PET/CT dataset. The uncertainty-aware approach can accurately predict the segmentation quality that enables automatic segmentation quality control"
X Link 2024-06-20T05:00Z 208.1M followers, [---] engagements
"Individualized cerebellar damage predicts the presence of behavioral disorders in children with brainstem tumors Communications Medicine Jia et al. employ a normative model to identify cerebellar damage patterns in children with brainstem tumors. Machine learning reveals that individualized cerebellar deviations predict social problems and withdrawn behaviours in these patients"
X Link 2025-04-14T12:32Z 208.1M followers, [--] engagements
"The unprecedented Paxlovid journey from milligrams to millions of patient doses during the Covid-19 pandemic Communications Medicine Yu et al. describe the challenges faced in the rapid development and upscaling of Paxlovid to meet the global demand for COVID-19 treatment. They respond to challenges by investing at risk integrating predictive tools in development strategy and implementing a diversified global supply chain"
X Link 2025-04-16T12:11Z 208.1M followers, [--] engagements
"Development and prospective validation of an artificial intelligence-based smartphone app for rapid intraoperative pituitary adenoma identification Communications Medicine Bou-Nassif et al. develop a smartphone app using AI and stimulated Raman histology to differentiate pituitary adenomas from normal tissue in real-time during surgery. Prospective validation on [--] patients shows high sensitivity and specificity with an external validation on [--] additional adenoma tumors"
X Link 2024-03-29T07:00Z 208.1M followers, [----] engagements
"Interpretable machine learning leverages proteomics to improve cardiovascular disease risk prediction and biomarker identification Communications Medicine Climente-González Oh et al. introduce an interpretable machine learning model that integrates plasma proteomics with clinical risk factors and employs an explainable boosting machine algorithm for risk prediction. Authors show that their model outperforms existing models in predicting risk for cardiovascular disease"
X Link 2025-06-09T11:31Z 208.1M followers, [--] engagements
"Accurate and interpretable drug-drug interaction prediction enabled by knowledge subgraph learning Communications Medicine Wang Yang et al. propose KnowDDI a graph neural network that leverages biomedical knowledge graphs for drug-drug interaction predictions. The model yields improved performance and interpretability over existing methods especially in scenarios with sparse knowledge graphs marking a significant advancement in biomedicine and healthcare"
X Link 2024-04-08T18:00Z 208.1M followers, [---] engagements
"Multi-modal Neuroimaging Phenotyping of Mnemonic Anosognosia in the Aging Brain Communications Medicine Bueichekú et al. use multimodal in vivo neuroimaging to investigate the brain characteristics of individuals presenting unawareness of memory loss who are at risk of Alzheimer’s disease due to age. They find unawareness of memory decline is an early behavioral sign that a person might develop Alzheimer’s disease"
X Link 2024-04-10T12:30Z 208.1M followers, [---] engagements
"Computer vision detects covert voluntary facial movements in unresponsive brain injury patients Communications Medicine Cheng et al. developed a computer vision tool (SeeMe) that detects low-amplitude facial movements in comatose brain injury patients. Purposeful responses are detected days before clinical detection suggesting that covert consciousness may often go unrecognized"
X Link 2025-09-02T14:11Z 2.1M followers, 45.3K engagements
"The World Trade Center exposome and health effects in 9/11 rescue and recovery workers Communications Medicine Rechtman et al. analyse the exposome of rescue and recovery workers who attended the World Trade Center on and after September [--] [----]. Mental and physical health outcomes associate with all aspects of occupational history as well as traumatic and environmental exposures"
X Link 2025-09-11T03:15Z 208.1M followers, [--] engagements
"Harnessing artificial intelligence to improve clinical trial design Communications Medicine Zhang et al. discuss how artificial intelligence (AI) can be used to optimize clinical trial design and potentially boost the success rate of clinical trials. AI has unparalleled potential to leverage real-world data and unlock valuable insights for innovative trial design"
X Link 2024-01-05T14:00Z 208.1M followers, [---] engagements
"Oxygen supplementation in anesthesia can block FLASH effect and anti-tumor immunity in conventional proton therapy Communications Medicine Iturri Bertho et al. analyze the effects of oxygen administration during anesthesia in conventional and FLASH proton therapy in a rat model. They demonstrate the detrimental effect of varying oxygen supply using histologic cytometric and behavioral analysis and highlighting the urgent need to optimize anesthesia protocols in pediatric oncology"
X Link 2024-01-18T19:00Z 208.1M followers, [---] engagements
"Plasmonic nano-aperture label-free imaging of single small extracellular vesicles for cancer detection Communications Medicine Ohannesian Mallick et al. demonstrate label-free counting and detection of microRNA cargoes for single small extracellular vesicles (sEVs) revealing elevated sEV counts and distinct molecular contents in samples from patients with cancer. Using a simple threshold of sEV count in a blind test classification of cancer vs. healthy samples is achieved with high sensitivity and specificity"
X Link 2024-06-06T16:00Z 208.1M followers, [---] engagements
"High tumor expression of CTLA4 identifies lymph node-negative basal-like breast cancer patients with excellent prognosis Communications Medicine Røssevold et al. identify a subset of patients with early-stage basal-like breast cancer with an excellent prognosis defined by high tumor expression of the immune checkpoint gene CTLA4. These patients are currently considered high-risk and receive extensive systemic treatment which the authors suggest could safely be de-escalated or omitted"
X Link 2025-07-06T12:01Z 208.1M followers, [---] engagements
"Small extracellular vesicles in follicular fluids for predicting reproductive outcomes in assisted reproductive technology Communications Medicine Muraoka et al. assess the potential of small non-coding RNAs derived from small extracellular vesicles contained within ovarian follicular fluid to determine in predicting assisted reproductive technology outcomes. They find that a combination of small ncRNAs were differentially expressed between reproductive outcomes"
X Link 2024-03-04T11:00Z 208.1M followers, [---] engagements
"Impact of gallbladder hypoplasia on hilar hepatic ducts in biliary atresia Communications Medicine Miyazaki Takami et al. assess the relationship between biliary atresia and the gallbladder in Sox17 haploinsufficient mice and human biliary atresia patients. They report findings on the perinatal pathological condition in which abnormalities in the gallbladder wall extend to the intrahepatic bile duct through the common hepatic duct"
X Link 2024-06-24T08:00Z 208.1M followers, [---] engagements
"Noninvasive and reliable automated detection of spreading depolarization in severe traumatic brain injury using scalp EEG - Communications Medicine Chamanzar et al. demonstrate the feasibility of using an automated algorithm to non-invasively detect spreading depolarizations in patients with severe traumatic brain injuries. With further testing the algorithm could be a useful tool in the prognostication of worsening brain injuries enabling clinicians to tailor treatments"
X Link 2023-08-19T00:00Z [----] followers, [---] engagements
"Machine learning models identify predictive features of patient mortality across dementia types Communications Medicine Zhang Song et al. develop machine-learning models to predict dementia patient mortality at one- three- five- and ten-year thresholds. The models identify dementia patients at risk of mortality using a limited set of dementia-related predictors and the stratified analyses reveal shared and distinct predictors of mortality across dementia types"
X Link 2024-03-04T14:00Z 208.1M followers, [---] engagements
"Estimating the risk of brain metastasis for patients newly diagnosed with cancer Communications Medicine Miccio et al. utilize the US National Cancer Database (NCDB) to develop models to estimate the risk of brain metastasis for newly-diagnosed cancers. They provide nomograms and a web tool for risk estimation across multiple cancer types"
X Link 2024-02-23T13:00Z 208.1M followers, [---] engagements
"Unravelling the complex causal effects of substance use behaviours on common diseases Communications Medicine Xue et al. use [--] Mendelian Randomization methods to investigate the causal relationship between seven substance use behavioural traits and health outcomes. They identify risk effects of alcohol consumption as well as dosage dependent effects of coffee and tea on cardiovascular disease and osteoarthritis respectively"
X Link 2024-03-26T11:00Z 208.1M followers, [---] engagements
"Variant calling from RNA-Seq data reveals allele-specific differential expression of pathogenic cancer variants Communications Medicine Bollas and Gaither et al. present a method to classify simple germline and somatic sequence variants called from tumor RNA sequencing data alone. This machine learning-based approach simplifies variant classification and illustrates the importance of RNA in cancer molecular profiling"
X Link 2025-06-20T09:48Z 208.1M followers, [--] engagements
"A nationwide study of risk factors for long COVID and its economic and mental health consequences in the United States Communications Medicine Kim identifies risk factors for long COVID and links long COVID to higher instances of job loss financial hardship and anxiety and depressive symptoms. Lost earnings due to long COVID among working-aged adults are estimated to total $218 billion in [----] indicating long COVID’s substantial public health and economic consequences among Americans"
X Link 2025-04-09T21:36Z 228.6M followers, [----] engagements
"Acquired resistance to immune checkpoint therapy is caused by glycoprotein non-metastatic melanoma protein B signal cascade Communications Medicine Chung et al. examine the levels of glycoprotein non-metastatic melanoma protein B (GPNMB) in the blood of patients with renal cell carcinoma who acquire resistance to immune checkpoint inhibitor therapy. Findings show that GPNMB levels are elevated and could serve as a prognosticator of and potential treatment target for treatment-resistant cancer"
X Link 2025-04-10T12:00Z 208.1M followers, [--] engagements
"The impact of prematurity on pediatric asthma morbidity and indices with environmental pollution and genetic susceptibility Communications Medicine Kelchtermans et al. analyze interactions between prematurity PM2.5 exposure and genetic susceptibility on asthma exacerbations in children. They find that combined effects produce outsized increases in exacerbation risk underscoring the need for targeted interventions"
X Link 2025-08-22T11:45Z 208.1M followers, [--] engagements
"Shifts in ophthalmic care utilization during the COVID-19 pandemic in the US Communications Medicine Li et al. use an analytic framework to identify care utilization patterns for [---] ocular diagnoses in the first two years of the COVID-19 pandemic in the US. Findings reveal lasting utilization reductions for most conditions particularly less severe ones with notable outliers and variations across diagnosis categories and pandemic sub-periods"
X Link 2024-01-15T13:00Z 208.1M followers, [---] engagements
"Impact of extended-course oral nirmatrelvir/ritonavir in established Long COVID: a case series Communications Medicine Cohen et al. report a patient-led case series of [--] individuals with Long COVID who initiated extended courses of Paxlovid outside of or within the context of an acute SARS-CoV-2 infection. Long courses of nirmatrelvir/ritonavir have meaningful benefits for some people with Long COVID but not all"
X Link 2025-01-12T13:19Z 208.1M followers, [---] engagements
"Overcoming challenges in the economic evaluation of interventions to optimise antibiotic use Communications Medicine Roope et al. discuss the importance of accounting for the broad benefits that occur as a consequence of optimising antibiotic use. They propose a threshold-based approach that estimates the minimum costs that would need to be averted by an intervention to make it cost-effective"
X Link 2024-05-30T11:00Z 208.1M followers, [---] engagements
"Humoral and cellular immune responses to COVID-19 mRNA vaccines in immunosuppressed liver transplant recipients Communications Medicine Nogimori Nagatsuka et al. present a longitudinal immunogenicity analysis of mRNA vaccination in liver transplant recipients and healthy donors. Despite a lower response to primary vaccination in transplant recipients a third booster improves antibody- and CD4 T cell-responses but not CD8 T cell-responses which need further improvement"
X Link 2024-03-05T07:00Z 208.1M followers, [---] engagements
"A comprehensive overview of the burden prevention and therapeutic aspects of arboviral diseases in India Communications Medicine Gupta et al. discuss the epidemiology and burden of major circulating arboviral diseases in India touching on diagnosis treatment and preventative measures. They highlight key research and policy gaps along with direction for future research to improve surveillance and control measures"
X Link 2025-07-21T11:07Z 208.1M followers, [--] engagements
"Projecting future fluid intake of Chinese children in a warming world Communications Medicine Zhu He Zhang et al. conduct a cross-sectional study examining the relationship between temperature and fluid intake in Chinese children. Findings reveal a 24 mL daily intake increase per 1 °C temperature rise and projections under climate change scenarios predict substantially higher hydration needs by 2099"
X Link 2025-06-24T11:31Z 208.1M followers, [--] engagements
"Combined use of Donepezil and Memantine increases the probability of five-year survival of Alzheimers disease patients Communications Medicine Yaghmaei et al. utilize doubly robust causal inference estimators and a large medical data set to evaluate the impact of combining Donepezil and Memantine on five-year survival since initial diagnosis of Alzheimer’s disease patients. A significant benefit to survival is seen when the drugs are combined"
X Link 2024-06-06T10:00Z 208.1M followers, [---] engagements
"Sepsis endotypes identified by host gene expression across global cohorts Communications Medicine Chenoweth et al. investigate heterogeneity in sepsis using host gene expression from multi-site international cohorts. Endotypes differentiated by mortality are identified and related molecular signatures implicate immune dysfunction in sepsis pathophysiology"
X Link 2024-06-28T11:30Z 208.1M followers, [---] engagements
"Mendelian randomization study of the relationship between blood and urine biomarkers and schizophrenia in the UK Biobank cohort Communications Medicine Cheng Bai et al. uncover associations between [--] blood and urine biomarkers and treatment-resistant schizophrenia using data from the UK Biobank. They find correlations between some blood and urine biomarkers and treatment resistant schizophrenia polygenic risk scores"
X Link 2024-03-13T08:00Z 208.1M followers, [---] engagements
"Meal timing trajectories in older adults and their associations with morbidity genetic profiles and mortality Communications Medicine Dashti et al. characterize whether meal timing changes with age in older adults using longitudinal data from nearly [----] individuals. They link later breakfast timing with increased multimorbidity and higher mortality risk and reveal behavioral and genetic factors that influence meal timing during aging"
X Link 2025-09-05T12:28Z 228.6M followers, [---] engagements
"Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome Communications Medicine Sighinolfi et al. evaluate the ovarian reserve in young healthy women with hereditary breast and/or ovarian cancer (HBOC) syndrome. A consistent trend for reduced reproductive potential in young healthy women with HBOC syndrome is observed particularly in BRCA1 pathogenic/likely-pathogenic variant carriers"
X Link 2025-04-07T11:31Z 208.1M followers, [---] engagements
"Lifestyle and demographic associations with [--] inflammatory and vascular stress biomarkers in [----] blood donors Communications Medicine Kjerulff et al. evaluate [--] biomarkers including markers of inflammation and vascular stress and their associations with demographic and lifestyle factors in healthy participants from the Danish Blood Donor study. Circulating biomarker levels varied according to sex age BMI and smoking status"
X Link 2024-04-01T07:00Z 208.1M followers, [---] engagements
"Description of an activity-based enzyme biosensor for lung cancer detection Communications Medicine Dempsey et al. present a graphene-based biosensor technology to detect enzyme activity in serum samples. A model is developed based on the activity of a panel of these biosensors to classify 90% of patients with lung cancer across all stages of disease providing a potentially useful screening technology"
X Link 2024-03-12T09:00Z 208.1M followers, [---] engagements
"Temporal trends of blood-based markers in various psychiatric disorders and their cross-sectional brain structure associations Communications Medicine Wang Zhou et al. conduct a nested case-control study within the UK Biobank cohort to investigate the temporal trends of blood-based biomarkers across major psychiatric disorders. They report significant temporal alterations in biomarkers and their associations with cross-sectional structural variations in specific brain regions highlighting disease-specific neurobiological correlates"
X Link 2025-07-08T12:32Z 208.1M followers, [--] engagements
"Preserving fairness and diagnostic accuracy in private large-scale AI models for medical imaging Communications Medicine Tayebi Arasteh Ziller et al. investigate how strict privacy safeguards affect AI learning in medical imaging. Their study finds that while enforcing privacy leads to a modest drop in accuracy it does not exacerbate biases for different patient groups though accuracy for intricate cases and specific subgroups may be more affected"
X Link 2024-03-27T08:00Z 208.1M followers, [---] engagements
"Rescue of lysosomal acid lipase deficiency in mice by rAAV8 liver gene transfer Communications Medicine Laurent et al. develop a liver-targeted gene therapy using recombinant adeno-associated viral vector (rAAV) to effectively cure Lysosomal acid lipase deficiency. This occurs via correction of lipid accumulation and normalized gene expression patterns and mitochondrial function in Lipa−/− mice"
X Link 2025-05-02T11:01Z 208.1M followers, [--] engagements
"Metformin use on the risks of depression and anxiety in people with type [--] diabetes Communications Medicine Kang Liu et al. evaluate the link between metformin use and depression in type [--] diabetes mellitus (T2DM) patients. Findings reveal that T2DM patients using metformin have a lower risk of depression and genetic analysis identifies KCNIP4 and BTG3 as key genes influencing this effect"
X Link 2025-08-20T12:31Z 208.1M followers, [--] engagements
"Enhanced fetal hematopoiesis in response to symptomatic SARS-CoV-2 infection during pregnancy Communications Medicine Alkobtawi Ngô et al. conduct transcriptome and phenotype analyses of umbilical cord blood cells from pregnant women upon SARS-CoV-2 infection. In the absence of vertical SARS-CoV-2 transmission erythroid cell signatures along with hypoxia pathway activation are observed in symptomatic infected mothers compared with control cases"
X Link 2024-01-08T07:00Z [----] followers, [---] engagements
"Modifying the glycosylation profile of SARS-CoV-2 spike-based subunit vaccines alters focusing of the humoral immune response in a mouse model Communications Medicine Renner et al. evaluate the impacts of different types of glycan moieties on the immunogenicity of SARS-CoV-2 spike in a mouse model. The presence of complex type glycans correlate with increased levels of neutralizing antibodies"
X Link 2025-05-02T11:31Z 208.1M followers, [--] engagements
"Respiratory modulations of cortical excitability and interictal spike timing in focal epilepsy: a case report Communications Medicine Kluger et al. investigate respiratory modulations of cortical excitability states in a patient with focal epilepsy using high-resolution magnetoencephalography. Respiration differentially modulates excitation-inhibition balance in focal epilepsy and the timing of epileptic spike generation depends on both excitability and respiratory states"
X Link 2025-05-01T12:01Z 208.1M followers, [--] engagements
"Pretrained patient trajectories for adverse drug event prediction using common data model-based electronic health records Communications Medicine Kim et al. develop an adverse drug event (ADE) prediction model using language model-based electronic health records (EHR) pretraining model. Authors show that EHR pretraining models can accurately predict ADEs with proper explanations"
X Link 2025-07-02T17:12Z 208.1M followers, [---] engagements
"Utilizing Google Trends data to enhance forecasts and monitor long COVID prevalence Communications Medicine Chu et al. use merged search volumes of long COVID symptoms derived from Google Trends data to investigate changing search patterns. Several specific symptoms increase in searches both before and after the rise in the searches for long COVID suggesting that search volumes can predict long COVID prevalence"
X Link 2025-05-27T12:01Z 208.1M followers, [---] engagements
"Identifying commonalities and differences between EHR representations of PASC and ME/CFS in the RECOVER EHR cohort Communications Medicine Powers et al. investigate commonalities and differences between electronic health record patterns associated with post-acute sequelae of SARS-CoV-2 infection and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Records of dyspnea fatigue and cognitive impairment are common diagnoses and recommend common symptom management"
X Link 2025-05-01T12:31Z 208.1M followers, [--] engagements
"Identifying outbreak risk factors through case-controls comparisons Communications Medicine Fefferman et al. propose applying a case-control framework as an outbreak epidemiological study design to promote evidence-based decision-making for prevention and response to outbreaks. They describe their framework and discuss case-control examples of how it can be applied"
X Link 2025-06-19T09:44Z 208.1M followers, [---] engagements
"Functionally enriched epigenetic clocks reveal tissue-specific discordant aging patterns in individuals with cancer Communications Medicine Herzog et al. dissect functionally enriched groups of CpG associated with cellular senescence proliferation and aging. Some non-cancer tissues from breast cancer patients show younger epigenetic ages than in controls while breast cancer tissue looks generally older providing evidence for discordant systemic aging in breast cancer"
X Link 2025-04-24T11:31Z 228.6M followers, [---] engagements
"Question-answering system extracts information on injection drug use from clinical notes Communications Medicine Mahbub et al. introduce a question-answering framework to extract injection drug use (IDU) details from unstructured clinical notes. The proposed framework demonstrates high performance and extracts IDU details efficiently facilitating informed care for those who inject drugs"
X Link 2024-05-07T05:30Z 208.1M followers, [---] engagements
"Serum metabolite levels identify incipient metastatic progression of rectal cancer Communications Medicine Bakke Bousquet et al. identify serum metabolite biomarkers at the time of primary tumour diagnosis in rectal cancer participants prone to metastatic progression. These individuals show higher serum metabolites of alanine lactate pyruvate and citrate compared to those without metastatic progression"
X Link 2025-05-13T11:31Z 208.1M followers, [--] engagements
"Cluster and survival analysis of UK biobank data reveals associations between physical multimorbidity clusters and subsequent depression Communications Medicine DeLong et al. investigate several clustering techniques to identify patterns of physical multimorbidity. They find several clusters which align to known body systems and use survival analyses to determine which clusters are most associated with depression"
X Link 2025-05-21T12:31Z 208.1M followers, [--] engagements
"Identifying multi-resolution clusters of diseases in ten million patients with multimorbidity in primary care in England Communications Medicine Beaney et al. compare co-occurrence and sequence-based embedding methods and apply graph-based clustering to identify clusters of diseases at multiple resolutions in over ten million people with multimorbidity. Interpretable clusters of diseases are found that correspond to both established and novel patterns"
X Link 2024-06-04T07:00Z 208.1M followers, [---] engagements
"The association between the gut microbiome and 24-h blood pressure measurements in the SCAPIS study Communications Medicine Lin et al. investigate the relationship between specific characteristics of the gut microbiome and 24-h ambulatory blood pressure measurements. Four gut microbial species and microbial diversity associate with 24-h blood pressure traits supporting a potential role for the gut microbiome in blood pressure regulation and variability"
X Link 2025-08-01T11:31Z 208.1M followers, [--] engagements
"Mapping multimorbidity progression among [---] diseases - Communications Medicine Han et al. present a framework to map the clusters of multimorbidity progression by examining the bi-directional causal progress between hundreds of diseases. This provides a comprehensive picture of how one disease influences and is influenced by the development of others and how they form clusters of disease trajectories"
X Link 2024-07-11T00:00Z [----] followers, [---] engagements
"Transmission risks of Omicron BA.5 following inactivated COVID-19 vaccines among children and adolescents in China Communications Medicine Guo Zeng Lu et al. assess SARS-CoV-2 Omicron BA.5 transmission and protection from inactivated vaccines among children and adolescents prior to the end of Zero-COVID measures in Urumqi China. Two vaccine doses provide improved protection against Omicron infection and reduced transmission versus a single dose when given within the same year"
X Link 2024-05-24T12:00Z 208.1M followers, [---] engagements
"Continuous vital sign monitoring of acute Lassa fever using wearable biosensor devices in West Africa Communications Medicine Page et al. use wearable biosensors to monitor vital sign trends in patients with Lassa fever in Sierra Leone. Tachycardia and reduced heart rate variability associate with poor outcomes though technical limitations hinder broader implementation"
X Link 2025-08-07T16:34Z 208.1M followers, [---] engagements
"Neutralizing antibodies after the third COVID-19 vaccination in healthcare workers with or without breakthrough infection Communications Medicine Reinholm et al. evaluate COVID-19 vaccine-induced binding and neutralizing antibodies against several SARS-CoV-2 variants [--] months post three doses of vaccines in healthcare workers. Thrice vaccinated individuals could mount an effective humoral response to most variants except for BQ.1.1 and XBB.1.5 emphasizing the need for new vaccine candidates"
X Link 2024-02-28T09:30Z 208.1M followers, [---] engagements
"A domain knowledge-based interpretable deep learning system for improving clinical breast ultrasound diagnosis Communications Medicine Yan Liang Zhang et al. propose a domain knowledge-based interpretable deep learning system to improve breast cancer risk prediction from multimodal ultrasound images. Its inherent interpretability enables effective human-machine collaboration and thus may aid clinical decision-making"
X Link 2024-05-21T11:00Z 208.1M followers, [---] engagements
"Kindness as a public health action Communications Medicine Nguyen and Lee discuss how universal practice of kindness is a public health action. Using empirical evidence of randomised controlled trials combined with Rose’s theoretical framework of preventive medicine authors propose how acts of kindness specifically self-kindness and self-compassion can improve mental health outcomes"
X Link 2025-05-12T12:01Z 208.1M followers, [--] engagements
"A Mendelian randomization analysis of cardiac MRI measurements as surrogate outcomes for heart failure and atrial fibrillation Communications Medicine Schmidt et al. use Mendelian randomization to identify (biventricular) cardiac MRI measurements with a strong association with heart failure and/or atrial fibrillation. Nine cardiac MRI measurements are identified that may be relevant to consider as surrogate outcomes in both research and clinical settings"
X Link 2025-05-13T10:32Z 208.1M followers, [--] engagements
"Refining the diagnosis of gestational diabetes mellitus: a systematic review and meta-analysis Communications Medicine Francis et al. perform a systematic review and meta-analysis to evaluate studies comparing perinatal outcomes among individuals with gestational diabetes mellitus (GDM). Their review and post hoc analysis find that maternal preconception weight and non-glucose-dependent biochemical markers could be a precision diagnostic approach to reducing variability in clinical outcomes following treatment"
X Link 2024-01-18T12:00Z 208.1M followers, [--] engagements
"Overcoming data scarcity in life-threatening arrhythmia detection through transfer learning Communications Medicine Monachino et al. investigate how to overcome the challenge of data scarcity in life-threatening arrhythmias (LTA) detection. They propose a transfer learning-based deep learning model that detects LTAs from single-lead ECGs with 92.68% sensitivity and 99.48% specificity and includes a confidence score to better support emergency response"
X Link 2025-07-19T14:42Z 208.1M followers, [--] engagements
"Pathophysiological profile of non-ventilated lung injury in healthy female pigs undergoing mechanical ventilation Communications Medicine Spinelli et al. show that non-ventilated lung injury develops within 24 h of unilateral mechanical ventilation in healthy pigs. Pathophysiological alterations included collapse hypoperfusion high inspiratory pressure and inflammation and were only partially mitigated by low tidal volume"
X Link 2024-02-21T08:00Z [----] followers, [---] engagements
"An ECG-based artificial intelligence model for assessment of sudden cardiac death risk Communications Medicine Holmstrom et al. train and validate a 12 lead ECG-based deep learning algorithm for sudden cardiac death risk assessment. The model accurately distinguishes sudden cardiac death cases from controls performing better than a conventional ECG risk model"
X Link 2024-03-01T17:00Z 208.1M followers, [---] engagements
"Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia Communications Medicine Fola et al. perform a nationwide genomic surveillance study of P. falciparum parasites across Zambia from samples collected in [----] and report key genetic metrics informing transmission intensity genetic relatedness and selection. These genomic surveillance data highlight the need to strengthen malaria control and surveillance of drug resistance"
X Link 2024-05-10T12:30Z 208.1M followers, [---] engagements
"Real-time motion-enabling positron emission tomography of the brain of upright ambulatory humans Communications Medicine Siva Bauer et al. use a motion-compatible brain imager to detect task-related brain activity in human participants walking in place. The feasibility of positron emission tomography (PET) neuroimaging of people performing motor tasks or who cannot remain still is demonstrated"
X Link 2024-06-26T19:00Z 208.1M followers, [---] engagements
"Tracing the origins of Plasmodium vivax resurgence after malaria elimination on Aneityum Island in Vanuatu Communications Medicine Sekine et al. traced the origins ofPlasmodium vivax resurgence after achieving malaria elimination on Aneityum Island Vanuatu. Analyzing five nuclear microsatellite markers samples from the resurgence and nearby Tanna Island exhibit identical or closely related haplotypes suggesting that imported infection contributes to the reintroduction"
X Link 2024-06-10T11:00Z 208.1M followers, [---] engagements
"Large language model comparisons between English and Chinese query performance for cardiovascular prevention Communications Medicine Ji et al. assess the responses of four major large language models in the context of cardiovascular disease prevention queries in both English and Chinese. The large language model chatbots exhibit significant disparities in performance across different models and languages with ChatGPT-4 outperforming the others in English"
X Link 2025-05-29T12:31Z 208.1M followers, [---] engagements
"Effects of COVID-19 pandemic on low birth weight in a nationwide study in India Communications Medicine Kumar et al. examine differences in birthweight and LBW between the pre COVID-19 (before Jan 2020) and COVID-19 (after March [----] onwards). Infants born during the COVID-19 period had lower birthweight compared to infants born during pre-COVID-19 periods"
X Link 2024-06-27T08:00Z 208.1M followers, [---] engagements
"Antimicrobial drug pricing Communications Medicine Despite the constant development of antimicrobial resistance (AMR) few new antimicrobials are currently becoming available clinically. Alternative approaches such as different mechanisms to fund their use are being explored to encourage development of new antimicrobials"
X Link 2024-10-23T10:59Z 208.1M followers, [---] engagements
"Structure-specific rigid dose accumulation dosimetric analysis of ablative stereotactic MRI-guided adaptive radiation therapy in ultracentral lung lesions Communications Medicine Bryant et al. report findings of a dosimetric analysis of adapted versus non-adapted radiation therapy plans of ultracentral lung lesions treated with ablative stereotactic MRI-guided adaptive radiation therapy. The differences demonstrated help to elucidate the therapeutic window improvements of daily plan adaptation"
X Link 2024-05-31T11:00Z 208.1M followers, [---] engagements
"Machine learning-based health environmental-clinical risk scores in European children Communications Medicine Guimbaud et al. use machine learning in a dataset of [----] European mother-child pairs to link early-life environmental exposures with children’s health. Through the computation of environmental-clinical risk scores they unveil complex interactions and nonlinear patterns among these factors underscoring their intricate role in children’s health"
X Link 2024-06-03T12:00Z 208.1M followers, [---] engagements
"Perceptions of the determinants of health across income and urbanicity levels in eight countries Communications Medicine Abdalla et al. examine how demographic factors shape perceptions of what matters for health across eight countries. They show that high income groups rank genetics as important urban groups rank healthcare as important and both low-income groups and non-urban groups rank social support as important"
X Link 2024-06-21T07:00Z 208.1M followers, [---] engagements
"Challenges in implementing cultural adaptations of digital health interventions Communications Medicine Nittas et al. discuss the importance of cultural adaptations in eliminating systemic exclusion of traditionally underserved cultural groups to minimize barriers to accessing digital healthcare interventions. They outline the existing challenges of the digital divide and provide recommendations to overcome them"
X Link 2024-01-11T12:00Z 208.1M followers, [---] engagements
"Epigenetic signatures in surrogate tissues are able to assess cancer risk and indicate the efficacy of preventive measures Communications Medicine Barrett Herzog and Aminzadeh-Gohari et al. demonstrate that tissue-specific epigenetic DNA methylation signatures define field cancerization and can predict cancer formation even from distant sources. Mifepristone reduced mammary gland cancer risk in mice by over 50% with this effect mirrored in changes to cervical DNA methylation patterns"
X Link 2025-04-25T12:01Z 208.1M followers, [--] engagements
"Risk factors for cardiogenic shock incidence and mortality after acute myocardial infarction: a systematic review and meta-analysis Communications Medicine Maimaitiming et al. systematically analyse the correlations between patient-related factors and cardiogenic shock after acute myocardial infarction (AMI-CS). The results reveal the risk factors in predicting the incidence and prognosis of AMI-CS which emphasizes early identification and targeted interventions for high-risk patients"
X Link 2025-06-13T11:31Z 208.1M followers, [--] engagements
"Potential influence of geomagnetic activity on blood pressure statistical fluctuations at mid-magnetic latitudes Communications Medicine He et al. analyze the correlation between blood pressure (BP) and geomagnetic activity (GMA) along with their quasi-periodic fluctuations. Their results show a significant positive correlation with multiple periodicities not observed in other factors like temperature and PM2.5 offering further evidence linking GMA and BP fluctuations"
X Link 2025-05-04T12:53Z 2.1M followers, [----] engagements
"Geospatial investigations in Colombia reveal variations in the distribution of mood and psychotic disorders Communications Medicine Song et al. conduct a geospatial analysis of variations in incidence of mood and psychotic disorders and access to care in Caldas Colombia. They show that many patients requiring only outpatient care live too far away to access it and identify hotspots of more severely ill patients highlighting the need for targeted interventions"
X Link 2024-02-23T16:00Z 208.1M followers, [---] engagements
"Association of Lifes Simple [--] lifestyle metric with cardiometabolic disease-free life expectancy in older British men Communications Medicine Wang et al. evaluate the association between adherence to the Life’s Simple [--] lifestyle metrics and cardiometabolic disease (CMD)-free survival in a population of older British men. Men with ideal levels of adherence remained CMD-free for four years longer than those with poor adherence with physical activity providing the greatest benefit"
X Link 2024-06-19T16:00Z 208.1M followers, [---] engagements
"Dynamic SARS-CoV-2 surveillance model combining seroprevalence and wastewater concentrations for post-vaccine disease burden estimates Communications Medicine Holm et al. present a SARS-CoV-2 surveillance model linking hospitalization seroprevalence and wastewater concentrations. They fit this model to epidemic data from Kentucky USA to generate counterfactual scenarios highlighting the plausible effects of vaccination and changes in dynamics due to emergence of new variants"
X Link 2024-04-16T11:00Z [----] followers, [---] engagements
"A deep network DeepOpacityNet for detection of cataracts from color fundus photographs Communications Medicine Elsawy Keenan Chen et al. detect cataracts from color fundus photography using an explainable deep learning network called DeepOpacityNet. DeepOpacityNet detects cataracts more accurately than ophthalmologists and demonstrates that the absence of blood vessels is an indicator that cataracts are present"
X Link 2024-01-18T08:00Z [----] followers, [---] engagements
"Safety and pharmacokinetics of the non-hormonal male contraceptive YCT-529 Communications Medicine Mannowetz et al. evaluate the safety and tolerability of the small molecule YCT-529 and show that single doses of up to 180 mg were well tolerated in healthy male subjects of this Phase 1a clinical trial. YCT-529 is developed as a non-hormonal oral male contraceptive pill with the intention to reduce the risk of unplanned pregnancies"
X Link 2025-07-29T11:53Z 208.1M followers, [--] engagements
"Remission of alcohol use disorder following traumatic brain injury with focal orbitofrontal cortex hemorrhage: case report and network mapping Communications Medicine Haque et al. report a case of chronic alcohol use disorder that had early remission following a traumatic brain injury with left orbitofrontal cortex intracerebral hemorrhage. Mapping of this lesion converges on recently described addictive behavior network maps but with inverse connectivity"
X Link 2025-03-13T19:32Z 208.1M followers, [--] engagements
"Spatial modeling connecting childhood atopic dermatitis prevalence with household exposure to pollutants Communications Medicine Ratley Zeldin et al. implicate xylene in the pathogenesis of atopic dermatitis by combining spatial analysis and patient surveys with prior epidemiological and mechanistic data. They propose that exposure of healthy skin commensals to xylene benzene and isocyantes in synthetic fabrics disrupts normal lipid metabolism and activates itching"
X Link 2024-04-23T11:00Z 208.1M followers, [---] engagements
"Distinct brain morphometry patterns revealed by deep learning improve prediction of post-stroke aphasia severity Communications Medicine Teghipco et al. use deep learning to assess whether the spatial interdependencies of multivariate brain morphometry patterns contain information that can improve prediction of aphasia severity post-stroke. They demonstrate that compared to classical machine learning deep learning gives better predictions"
X Link 2024-06-25T06:00Z 208.1M followers, [---] engagements
"Inter-seizure variability in thalamic recruitment and its implications for precision thalamic neuromodulation Communications Medicine Salami et al. explore how seizure properties can guide thalamic modulation site selection in epilepsy. Spiking-pattern seizures show limited thalamic spread while faster (10-20 Hz) broad-onset seizures spread early especially to the centromedian and pulvinar suggesting they are better targets for these seizures than the anterior nucleus"
X Link 2025-06-11T12:02Z 208.1M followers, [--] engagements
"Geospatial analysis and scale-up modelling of the impact of mobile programming on access to essential childhood vaccinations in Yemen Communications Medicine Garber et al examine the impact of mobile programming on childhood vaccination access in Yemen using geospatial modelling and conflict-adjusted datasets. The modelling also identifies a set of optimal locations for new vaccination sites and quantifies their potential impact on vaccine accessibility"
X Link 2025-05-09T11:31Z 208.1M followers, [--] engagements
"Cardiotoxic profiles of CAR-T therapy and bispecific T-cell engagers in hematological cancers Communications Medicine Karthikeyan et al. use WHO pharmacovigilance data to evaluate cardiotoxicity profiles of CAR-T therapy and bispecific T-cell engagers. They find evidence of severe adverse cardiovascular events including heart failure in some patients treated with tisagenlecleucel"
X Link 2024-06-26T12:00Z 208.1M followers, [---] engagements
"Association of SARS-CoV-2 vaccination status with risk of influenza-like illness and loss of workdays in healthcare workers Communications Medicine Dörr Lacy et al. evaluate the association between SARS-CoV-2 vaccination status and influenza-like illness and sick leave among [----] Swiss healthcare workers. SARS CoV-2 vaccination is associated with increased illness symptoms and more days of sick leave while influenza vaccination is associated with a decreased risk of both outcomes"
X Link 2025-08-09T20:33Z 2.1M followers, 114.7K engagements
"Determining frailty index thresholds for older people across multiple countries in sub-Saharan Africa Communications Medicine Dzando et al. identify locally relevant frailty thresholds for older people in Sub-Saharan Africa through Receiver Operating Characteristic analysis and random-effects meta-analysis. Findings demonstrate variability in population level thresholds with a pooled threshold of [----] demonstrating good sensitivity and specificity across the populations"
X Link 2025-07-07T12:01Z 208.1M followers, [--] engagements
"Recent advances in CRISPR-based single-nucleotide fidelity diagnostics Communications Medicine Kohabir et al. review recent advances in CRISPR-based diagnostics aimed at achieving single-nucleotide fidelity for clinical applications. By dissecting strategies in gRNA design effector selection and reaction conditions the authors highlight how these innovations can support precise and accessible genetic testing at the point-of-care"
X Link 2025-07-25T14:50Z 208.1M followers, [--] engagements
"Impact of clinical preparation steps and use of sex-specific reference for accurate antibiotic monitoring in body fluids Communications Medicine Domes et al. use enhanced Raman spectroscopy to quantify drugs within body fluids. Freezing centrifugation and filtration result in additive loss of piperacillin from human urine while using a reference urine pool from same-sex donors yield superior results to a mixed-sex urine pool"
X Link 2025-05-06T12:31Z 208.1M followers, [--] engagements
"Long-term immune responses to SARS-CoV-2 Omicron BA.4/5 mRNA booster in people living with HIV Communications Medicine Augello et al. assess long-term immune responses to Omicron BA.4/5 booster in people living with HIV. The vaccine enhances immunity with T cell responses stable and cross-reactive but antibody responses short-lived and imprinted to the ancestral virus; HIV-related T cell dysfunction reduces antibody peak and durability"
X Link 2025-04-18T11:16Z 208.1M followers, [---] engagements
"Rabies virus large protein-derived T-cell immunogen facilitates rapid viral clearance and enhances protection against lethal challenge in mice Communications Medicine Bai et al. present a novel mRNA rabies vaccine RABV-G-LT which combines glycoprotein and T-cell immunogens to enhance protection against rabies. This dual-immunogen approach elicits robust neutralizing antibodies and T-cell responses in mice and non-human primates providing a promising strategy for more effective and cost-efficient rabies prevention"
X Link 2025-05-09T12:31Z 208.1M followers, [--] engagements
"Revealing speckle obscured living human retinal cells with artificial intelligence assisted adaptive optics optical coherence tomography Communications Medicine Das and colleagues develop and evaluate a parallel discriminator generative adversarial network (P-GAN) for improved in-vivo imaging of retinal cellular structures. The P-GAN network improves retinal pigment epithelium contrast 3.5-fold and the overall throughput 99-fold"
X Link 2024-05-12T12:00Z 208.1M followers, [---] engagements
"Predicting which patients with cancer will see a psychiatrist or counsellor from their initial oncology consultation document using natural language processing Communications Medicine Nunez et al. investigate the use of natural language processing to predict which patients with cancer will see a psychiatrist or counselling using the initial oncology consultation document. Their study supports the use of such techniques with widely-available medical documents to better address the psychosocial needs of cancer patients"
X Link 2024-04-15T13:00Z [----] followers, [---] engagements
"Proteomic features of soft tissue tumours in adolescents and young adults Communications Medicine Tam et al. compare molecular features between adolescents and young adult (AYA) and older adult (OA) patients with soft tissue tumours and identify that components of the spliceosome complex are independent prognostic factors for metastasis free survival in AYA patients"
X Link 2024-05-22T06:00Z [----] followers, [---] engagements
"Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type [--] diabetes: a systematic review Communications Medicine Felton et al. conduct a systematic review to determine the utility of islet autoantibodies as biomarkers of type [--] diabetes heterogeneity. They find that islet autoantibodies are most likely to be useful for patient stratification prior to clinical diagnosis"
X Link 2024-04-11T07:00Z 208.1M followers, [---] engagements
"Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization Communications Medicine Morrow et al. evaluate the clinical and social parameters of Scottish patients who were previously admitted to hospital with SARS-CoV-2 infection. They report that socioeconomic deprivation influences illness trajectory after COVID-19"
X Link 2024-03-11T11:00Z 208.1M followers, [---] engagements
"Peripheral nerve regeneration following scaffold-free conduit transplant of autologous dermal fibroblasts: a non-randomised safety and feasibility trial Communications Medicine Ikeguchi et al. established nerve conduits from three patients’ dermal fibroblasts using a bioprinter and transplanted them back into the patients’ nerve defects. No adverse events occurred and the nerves recovered following the transplant"
X Link 2024-02-05T08:07Z 208.1M followers, [---] engagements
"Cochlear gene therapy restores hearing and auditory processing in an atypical DFNB9 mouse model Communications Medicine Benamer et al. develop a knock-in mouse model carrying the E1799del otoferlin mutation to study the atypical DFNB9 variant form of deafness. They show the mouse model exhibits abnormal otoferlin distribution failure of synaptic transmission in inner hair cells and profound hearing loss all of which can be restored with AAV gene therapy"
X Link 2025-06-27T12:01Z 208.1M followers, [--] engagements
"Utility and cost-effectiveness of LiverMultiScan for MASLD diagnosis: a real-world multi-national randomised clinical trial Communications Medicine Shumbayawonda et al. examine the impact of multi-parametric MRI in managing MASLD in a multinational randomised clinical trial. Findings show multi-parametric MRI is cost-effective reduces consultations and improves diagnostic rates compared to standard of care enhancing diagnostic accuracy and streamlining pathways without requiring additional resources"
X Link 2025-04-09T11:31Z 208.1M followers, [--] engagements
"Relationship between adolescent anemia and school attendance observed during a nationally representative survey in India Communications Medicine De Neve et al. determine the relationship between anemia and school attendance among adolescents using a large national dataset from India. In this within-household analysis the relationship between anemia and schooling is more muted compared to more conventional analyses which do not account for all household-level factors"
X Link 2024-06-26T04:00Z [----] followers, [---] engagements
"Demographic variation in pain across [--] countries Communications Medicine Macchia et al. use nationally representative data from [--] countries (N = 202898) and a random effects meta-analysis to examine the proportion of people in pain across key demographic groups. Findings show substantial variation in pain across these groups and countries"
X Link 2025-05-16T12:02Z 208.1M followers, [---] engagements
"Long-term risk of malignancies in persons with ischemic heart disease treated with trimetazidine dihydrochloride Communications Medicine Cheng et al. explore the impact of trimetazidine an anti-ischemic agent that preferentially potentiates cellular glucose oxidation on cancer risk. Findings show an association of use with a reduced long-term risk of malignancies"
X Link 2025-04-16T11:32Z 208.1M followers, [--] engagements
"Relationship between grammar and schizophrenia: a systematic review and meta-analysis Communications Medicine Elleuch et al perform a systematic review and meta-analysis to evaluate the association between grammatical impairments and schizophrenia. Large effect size deficits in grammatical comprehension and production occur in this illness highlighting the need for targeted interventions to address language use in people with psychotic disorders"
X Link 2025-06-16T13:20Z 208.1M followers, [---] engagements
"Phase [--] dose expansion and biomarker study assessing first-in-class tumor microenvironment modulator VT1021 in patients with advanced solid tumors Communications Medicine Chen et al. report findings from a phase [--] dose expansion study of the tumor microenvironment modulator VT1021 in patients with solid tumors. VT1021 is found to be safe and tolerable with preliminary evidence of efficacy and biomarkers of response"
X Link 2024-05-30T17:00Z 208.1M followers, [---] engagements
"Deep learning for video-based assessment of endotracheal intubation skills Communications Medicine Ainam et al. introduce a video-based system to assess endotracheal intubation (ETI) skills leveraging 2D and 1D convolutional models with a cross-view attention module to analyze complex patterns. The system effectively differentiates between experts and novices improving the objectivity and efficiency of ETI training and certification"
X Link 2025-05-05T11:31Z 208.1M followers, [--] engagements
"Iron homeostasis and cytokine responses in Gabonese children with febrile illness Communications Medicine Mayr Ndong et al. investigate the interplay between anemia iron homeostasis and immune activation in a retrospective cross-sectional study of Gabonese children with acute febrile illness. Anemia rates are linked to inflammation and iron deficiency with pathogen-specific immune markers correlating with iron availability"
X Link 2025-08-03T02:22Z 208.1M followers, [--] engagements
"Large-scale data reveal disparate associations between leisure time physical activity patterns and mental health Communications Medicine Zhou et al. analyze leisure time physical activity and self-reported mental health in people of different ages in China. Exercise is associated with better mental health even if exercise is of moderate intensity"
X Link 2024-01-08T10:00Z 208.1M followers, [--] engagements
"Machine learning identifies risk factors associated with long-term sick leave following COVID-19 in Danish population Communications Medicine Jakobsen et al. analyze data from a cohort of [-----] individuals from Denmark with causal machine learning and identify age sex high BMI and depression as key factors for long-term sick leave following SARS-CoV-2 infection"
X Link 2024-01-22T09:00Z 208.1M followers, [---] engagements
"SARS-CoV-2 dynamics in New York City during March 2020August [----] Communications Medicine Yang et al. utilize a model-inference system and multiple datasets to reconstruct the underlying SARS-CoV-2 transmission dynamics and validate the estimates using wastewater viral load data. This study estimates key epidemiological variables including infection rate and transmissibility for each variant and infection-fatality risk in New York City during March 2020August 2023"
X Link 2025-04-29T12:01Z 208.1M followers, [--] engagements
"Preclinical evaluation of small molecule inhibitors as early intervention therapeutics against Russells viper envenoming in India Communications Medicine Rudresha et al. evaluated small molecule inhibitors as early intervention therapeutics against Russell’s viper (Daboia russelii) envenoming. Varespladib and marimastat effectively neutralise the toxicities of pan-Indian Daboia russelii venom in vitro and in vivo including with delayed treatment"
X Link 2025-06-13T07:02Z 208.1M followers, [--] engagements
"Precision prognostics for cardiovascular disease in Type [--] diabetes: a systematic review and meta-analysis Communications Medicine Ahmad Lim Morieri Tam et al perform a systematic review and meta-analysis of biomarkers genetic markers and risk scores for prediction of cardiovascular outcomes in Type [--] diabetes. A few prognostic markers are identified that provide incremental predictive utility beyond established cardiovascular risk factors"
X Link 2024-01-31T08:00Z 208.1M followers, [---] engagements
"A cross-sectional and population-based study from primary care on post-COVID-19 conditions in non-hospitalized patients Communications Medicine Ose et al. conduct a questionnaire-based survey of post COVID-19 condition (PCC) symptoms among primary care patients with and without a diagnosis of COVID-19. They find reporting of PCC symptoms highly prevalent in all patients and highlight the challenges of accurate diagnosis of PCC due to the overlap with non-COVID-related symptoms"
X Link 2024-02-26T12:00Z 208.1M followers, [---] engagements
"The importance of funding and investment to strengthen data science in Africa Communications Medicine Kayalioglu et al. explore the underutilization of data science (DS) to improve health outcomes in Africa and advocate for increased strategic investment in DS infrastructure talent development and research funding. They highlight current challenges while proposing collaborative efforts to build sustainable locally driven DS growth across Africa"
X Link 2025-08-13T11:43Z 208.1M followers, [--] engagements
"Generative deep learning furthers the understanding of local distributions of fat and muscle on body shape and health using 3D surface scans Communications Medicine Leong et al. develop a generative deep learning model that produces analyzable dual energy X-ray absorptiometry (DXA) scans from 3D body surface scans. Model-generated DXA scans are analyzed using clinical commercial software and yield accurate quantities of fat lean and bone mass for total body and body subregions"
X Link 2024-02-15T09:00Z [----] followers, [---] engagements
"Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer Communications Medicine Cheng and Lama et al. developed a synergistic dual-modality AI framework for prediction of MMRd/MSI-High status in colorectal cancer and PD-L1 status in breast cancer. Their model which analyzes H&E and IHC images achieves clinical grade performance and identifies patients with improved outcomes on pembrolizumab immunotherapy"
X Link 2025-08-29T15:41Z 208.1M followers, [---] engagements
"A cross-national analysis of demographic variation in self-rated mental health across [--] countries Communications Medicine Okafor et al. analyze survey responses from adults in [--] countries to explore differences by age gender education and other characteristics in their rating of their mental health. Self-rated mental health is generally higher in some African countries and among older adults men married individuals and frequent religious service attendees"
X Link 2025-09-01T11:41Z 208.1M followers, [---] engagements
"Multi-scale V-net architecture with deep feature CRF layers for brain extraction Communications Medicine Park et al. improve a base segmentation model for brain extraction to increase robustness and go beyond the provided ground truth segmentation. Brain extraction improves when data is extracted from normal and clinical data using this model"
X Link 2024-02-27T11:00Z 208.1M followers, [---] engagements
"Keratinocyte SR-B1 expression and targeting in cytokine-driven skin inflammation Communications Medicine Trujillo et al. identify scavenger receptor class B type I (SR-B1) as a keratinocyte marker of skin inflammation and a potential therapeutic target. Topically delivered HDL-like nanoparticles target SR-B1 reduce inflammatory signaling in keratinocytes and improve imiquimod-induced inflammation in murine models"
X Link 2025-04-28T12:02Z 208.1M followers, [--] engagements
"Synthetic modified vaccinia Ankara vaccines confer cross-reactive and protective immunity against mpox virus Communications Medicine Chiuppesi et al. demonstrate that COVID-19 vaccine COH04S1 harboring a synthetic modified vaccinia Ankara-vector elicits cross-reactive responses against mpox virus (MPXV) similar to those induced by FDA-approved mpox vaccine JYNNEOS in healthy adults and non-human primates. COH04S1 also confers protective immunity against MPXV in a mouse model of mpox"
X Link 2024-02-21T13:00Z 208.1M followers, [---] engagements
"Cardiologist-level interpretable knowledge-fused deep neural network for automatic arrhythmia diagnosis Communications Medicine Jin et al. develop a deep learning-based model for diagnosing arrhythmias based on a large-scale ECG dataset. The model demonstrates cardiologist-level accuracy and can potentially improve the efficiency and accuracy of ECG detection in remote and underdeveloped areas offering a promising prospect for telemedicine"
X Link 2024-03-01T12:00Z 208.1M followers, [---] engagements
"Longitudinal study of risk factors predicting cannabis use disorder in UK young adults and adolescents Communications Medicine Skumlien et al. investigate whether eight factors predict cannabis use disorder in a 12-month longitudinal study. Adolescent age and baseline cannabis use disorder but not gender cannabis use frequency alcohol use tobacco use negative life events or the COVID-19 lockdown are associated with more severe cannabis use disorder at follow-up"
X Link 2025-08-14T11:45Z 208.1M followers, [---] engagements
"Effects of short-term moderate intensity exercise on the serum metabolome in older adults: a pilot randomized controlled trial Communications Medicine Wong et al. conduct a pilot randomized controlled trial on the effects of twelve weeks of exercise on the serum metabolome in older adults. The authors identify changes in metabolites related to mitochondrial fuel oxidation and amino acid pathways and relate these to imaging markers of cardiac aging in post-hoc analyses"
X Link 2024-06-03T05:00Z 208.1M followers, [---] engagements
"Whole body physiology model to simulate respiratory depression of fentanyl and associated naloxone reversal Communications Medicine Baird et al model opioid overdose and naloxone administration in a whole-body physiology model. The derived total naloxone rescue doses obtained are much higher than the current suggested guidelines"
X Link 2024-06-25T16:00Z 208.1M followers, [---] engagements
"Adverse childhood experiences increase the long-term accumulation of morbidity in women Communications Medicine Rocca et al. examine the effect of early-life adverse experiences including early adulthood on late-life morbidity using a cohort study in the US. The authors show that both adverse childhood experiences and abuse in childhood or early adulthood are associated with an accelerated accumulation of morbidity later in life"
X Link 2025-08-01T12:31Z 208.1M followers, [--] engagements
"Prioritizing mental health support for physician-scientist trainees Communications Medicine Tuazon et al. highlight the mental health challenges facing physician-scientist trainees who have a dual commitment to advancing clinical care and undertaking research. The authors outline the critical gaps in mental health support structures available to this unique trainee population and provide recommendations to redress the concerns discussed"
X Link 2025-05-12T12:31Z 208.1M followers, [--] engagements
"Generative deep learning for the development of a type [--] diabetes simulator Communications Medicine Mujahid et al. develop a type [--] diabetes patient simulator using a conditional sequence-to-sequence deep generative model. Their approach captures causal relationships between insulin carbohydrates and blood glucose levels producing virtual patients with similar responses to real patients in open and closed-loop insulin therapy scenarios"
X Link 2024-03-27T16:00Z 208.1M followers, [--] engagements
"Tethered spinal cord tension assessed via ultrasound elastography in computational and intraoperative human studies Communications Medicine Kerensky et al. quantify tension across human spinal cords in computational simulations a cadaveric benchtop model and a neurosurgical case series. Their direct methodology successfully differentiates stretched spinal cords from healthy states in all sub-studies"
X Link 2024-01-10T17:00Z [----] followers, [--] engagements
"Real-world impact of physical activity reward-driven digital app use on cardiometabolic and cardiovascular disease incidence Communications Medicine Senderey et al. examine the real-world impact of a reward-driven physical activity app on cardiometabolic and cardiovascular disease incidence using electronic health records from Israel’s largest healthcare organization. App users have a lower risk of developing cardiovascular disease stroke and type [--] diabetes"
X Link 2025-04-17T11:02Z 208.1M followers, [--] engagements
"Mediation of the association between disadvantaged neighborhoods and cortical microstructure by body mass index - Communications Medicine Kilpatrick et al. investigate the relationship between neighborhood disadvantage trans-fatty acid intake body mass index stress and cortical microstructure. Results suggest obesogenic aspects of neighborhood disadvantage could disrupt information processing flexibility in regions involved in reward emotion regulation and cognition"
X Link 2023-09-15T00:00Z [----] followers, 15.9K engagements
"Predicting future hospital antimicrobial resistance prevalence using machine learning Communications Medicine Vihta et al. use past hospital data including bloodstream infection cases susceptibilities and antimicrobial use to predict future resistance prevalence. Machine learning can improve the accuracy of predictions potentially impacting interventions"
X Link 2024-10-17T10:32Z 208.1M followers, [---] engagements
"Independent transcriptional patterns reveal biological processes associated with disease-free survival in early colorectal cancer Communications Medicine Knapen et al. apply consensus-independent transcriptional component analysis to dissect transcriptomes into statistically independent transcriptional components in early colorectal cancer. Their findings identify [--] biological processes associated with disease-free survival which enables stratification of patients into different subgroups"
X Link 2024-06-02T13:00Z 208.1M followers, [---] engagements
"High diversity of Escherichia coli causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approach Communications Medicine Pearse et al. use whole genome sequencing to describe the antigenic and overall diversity of [---] Escherichia coli isolates causing invasive infections in neonates in a single hospital in Malawi. High levels of O-antigen diversity are found highlighting the difficulty of developing a vaccine for this patient population"
X Link 2025-08-12T11:42Z 208.1M followers, [--] engagements
"AAV9-cBIN1 gene therapy rescues chronic heart failure due to ischemic cardiomyopathy in a canine model Communications Medicine Khan et al. perform AAV9-cBIN1 gene therapy in a canine model of acquired chronic ischemic cardiomyopathy. They show AAV9-cBIN1 therapy mitigates disease progression and can reverse heart failure in this model"
X Link 2025-04-21T12:31Z 208.1M followers, [---] engagements
"Mendelian randomization reveals interactions of the blood proteome and immunome in mitral valve prolapse Communications Medicine Moncla et al. scrutinize the role of circulating proteome in mitral valve prolapse development. Integration conducted on large-scale cross-modality data uncover a causal role of the circulating proteome immunome and macrophage M2 polarization in mitral valve prolapse"
X Link 2024-06-21T11:00Z 208.1M followers, [---] engagements
"S100A8/A9 predicts response to PIM kinase and PD-1/PD-L1 inhibition in triple-negative breast cancer mouse models Communications Medicine Begg et al. show that S100A8/9 expression is associated with risk of progression in early-stage triple-negative breast cancer cohorts. Using a small inhibitor screen the authors identify PIM kinase inhibitors to target S100A8/A9 expression improving antitumor response when combined with immune checkpoint blockade in mice"
X Link 2024-02-26T08:00Z 208.1M followers, [---] engagements
"Obstructive sleep apnea severity varies by season and environmental influences such as ambient temperature Communications Medicine Lechat et al. examines the severity of obstructive sleep apnea (OSA) using a large global dataset of users of an FDA-validated under-the-mattress sensor. These results demonstrate a seasonal component in the severity of OSA and show that this effect is partially explained by ambient temperature and variations in sleep duration"
X Link 2025-08-21T12:41Z 208.1M followers, [--] engagements
"Utility of smart watches for identifying arrhythmias in children Communications Medicine Zahedivash et al. undertake a single center retrospective analysis of patients less than [--] years of age with history of an arrhythmia to determine whether a wearable device can capture arrhythmias. Arrhythmias are identified in 28% of patients mainly the difficult to identify supraventricular tachycardias"
X Link 2024-01-10T09:00Z 208.1M followers, [--] engagements
"18FFluorThanatrace PET imaging as a biomarker of response to PARP inhibitors in breast cancer Communications Medicine Gitto Pantel et al. evaluate a PARP-targeted PET imaging ligand 18 FFlourThanatrace as a biomarker of response to PARP inhibitors in patients with breast cancer. There is 18 FFlourThanatrace uptake in the tumor before treatment and a decline in uptake after PARP inhibitor therapy initiation correlating with patient progression free survival"
X Link 2025-04-15T11:32Z 208.1M followers, [--] engagements
"Assessing regional variations and sociodemographic barriers in the progress toward UNAIDS 95-95-95 targets in Zimbabwe Communications Medicine Chowdhury et al. conducted a geospatial analysis to identify distinct regional patterns in progress toward the 95-95-95 HIV care targets in Zimbabwe. They reveal local areas with specific care needs highlighting significant spatial disparities and the influence of socio-demographic factors on gaps in achieving these targets"
X Link 2025-05-01T11:15Z 208.1M followers, [--] engagements
"Proteome profiling of home-sampled dried blood spots reveals proteins of SARS-CoV-2 infections Communications Medicine Fredolini et al. present a proteomics analysis of home-sampled dried blood spots taken from the general population in Stockholm during the COVID-19 pandemic. The study provides insights into the molecular effects of SARS-CoV-2 infection in non-hospitalized individuals and demonstrates the compatibility of self-sampled blood spots with proteomics"
X Link 2024-05-03T17:00Z 208.1M followers, [---] engagements
"Increased testing is needed for Mpox in DR Congo to urgently curb disease spread Communications Medicine Imani-Musimwa et al. describe the precarious situation in the DRC exacerbated by armed conflict poor infrastructure and limited healthcare resources and call for urgent action to enhance Mpox testing and control efforts which could significantly reduce the outbreak’s impact and improve health security in Africa"
X Link 2025-07-24T14:49Z 208.1M followers, [---] engagements
"Early elevated IFN is a key mediator of HIV pathogenesis Communications Medicine Le Buanec et al. compared distribution and frequency of cell markers associated with immune dysfunction between HIV elite controllers (EC) and untreated non-EC. They demonstrate that untreated HIV-infected individuals exhibit structurally and functionally impaired immune subsets as a consequence of excessive levels of serum IFNα"
X Link 2024-05-03T06:30Z 208.1M followers, [---] engagements
"UK Biobank data demonstrate long-term exposure to floods is a risk factor for incident dementia Communications Medicine Wu et al. investigate the association between flooding exposure and incident dementia using conditional logistic regression models. Flooding exposure is linked to an elevated risk of incident dementia with significant variations observed across age groups and between sexes"
X Link 2025-04-08T11:01Z 208.1M followers, [--] engagements
"Super-resolution neural networks improve the spatiotemporal resolution of adaptive MRI-guided radiation therapy Communications Medicine Grover et al. describe the training deployment and evaluation of real-time super-resolution imaging for MRI-guided radiation therapy. Volunteer phantom and simulation experiments demonstrate that super-resolution can increase the spatiotemporal resolution of real-time MRI guidance"
X Link 2024-04-10T08:00Z 208.1M followers, [---] engagements
"Implementing health economics for pharmacogenomics research translation in Africa Communications Medicine Alimohamed et al. outline the current pharmacogenomics landscape in Africa. They explore the role of health economics in its clinical translation and propose context-sensitive strategies for equitable implementation across the continent"
X Link 2025-07-05T12:01Z 208.1M followers, [---] engagements
"Multi-model assurance analysis showing large language models are highly vulnerable to adversarial hallucination attacks during clinical decision support Communications Medicine Omar et al. test six leading large language models with [---] doctor-designed clinical vignettes containing a single fake lab value sign or disease. They show that the models repeat or elaborate on the planted error in up to [--] % of cases with a simple mitigation prompt halving the rate but not eliminating the risk"
X Link 2025-09-30T16:49Z 2.1M followers, [----] engagements
"Forecasting influenza hospital admissions within English sub-regions using hierarchical generalised additive models Communications Medicine Mellor et al. introduce a new method for forecasting hospital admissions with seasonal influenza in a resurgent season that can be used to inform policy makers. The developed generalized additive model shows improved performance over other time series approaches when scored using probabilistic methods"
X Link 2024-01-23T14:00Z 208.1M followers, [--] engagements
"Molecular analysis for ovarian cancer detection in patient-friendly samples Communications Medicine Wever et al. explore the use of different types of patient-friendly material including urine for the detection of ovarian cancer by methylation and copy number analysis. Upon continued development DNA-based testing in cervical scrapes and urine could aid ovarian cancer diagnosis"
X Link 2024-05-20T15:00Z 208.1M followers, [---] engagements
"Optimal timing for atrial fibrillation patients to undergo catheter ablation Communications Medicine Lin et al. investigate the impact of diagnosis-to-ablation timing on atrial fibrillation (AF) recurrence after catheter ablation. This study finds that early catheter ablation characterized as diagnosis-to-ablation in less than [--] years is preferable for maintaining sinus rhythm particularly in persistent AF"
X Link 2025-07-10T11:31Z 208.1M followers, [--] engagements
"Improvements induced by retinal gene therapy with voretigene neparvovec depend on visual cortical hemispheric dominance mechanisms Communications Medicine Ferreira M et al. investigate the cortical response to visual function restoration in [--] patients with RPE65-RD treated with voretigene neparvovec using psychophysical and neuroimaging methods. The authors found significant improvements in light sensitivity and neural response under low luminance conditions particularly in the right hemisphere"
X Link 2025-04-30T12:31Z 208.1M followers, [--] engagements
"Rapamycin treatment for Alzheimers disease and related dementias: a pilot phase [--] clinical trial Communications Medicine Gonzales et al. conducted an open-label phase [--] clinical trial of rapamycin for mild cognitive impairment and dementia due to Alzheimer’s disease. Rapamycin is not detected in cerebrospinal fluid before or after treatment but there are changes in multiple neurodegenerative diseases and inflammatory biomarkers from baseline to post-treatment"
X Link 2025-05-22T23:40Z 208.1M followers, [---] engagements
"Performance assessment and economic analysis of a human Liver-Chip for predictive toxicology Communications Medicine Ewart et al. assess the performance of a human Liver-Chip for predictive toxicology. They also perform an economic analysis to demonstrate its potential financial value for the pharmaceutical industry"
X Link 2025-08-27T19:14Z 208.1M followers, [--] engagements
"Digital twin simulation modelling shows that mass testing and local lockdowns effectively controlled COVID-19 in Denmark - Communications Medicine Grsbll et al. use a detailed individual-based simulation model of SARS-CoV-2 transmission to evaluate mass testing and local lockdowns during the Alpha wave in Denmark in counterfactual scenarios. The model predicts that the combination of these measures prevented a large increase in hospitalizations while increasing overall societal freedom"
X Link 2024-10-04T00:00Z 208.1M followers, [--] engagements
"A phase IIb randomized placebo-controlled trial testing the effect of MAG-EPA long-chain omega-3 fatty acid dietary supplement on prostate cancer proliferation Communications Medicine Robitaille et al. report findings from a phase IIb randomized placebo-controlled trial evaluating the effect of a long-chain omega-3 fatty acid MAG-EPA dietary supplement on prostate cancer proliferation. The dietary supplement had no effect on the primary outcome of prostate cancer proliferation according to Ki-67 expression"
X Link 2024-03-28T08:00Z 208.1M followers, [---] engagements
"A comprehensive AI model development framework for consistent Gleason grading Communications Medicine Huo Ong et al. present a comprehensive workflow to try to overcome key limitations in prior approaches for artificial intelligence (AI)-assisted prostate cancer Gleason grading. Their approach incorporates automated quality control efficient annotation and visualization and pathologist-AI interaction"
X Link 2024-06-04T19:00Z 208.1M followers, [---] engagements
"Community-based screening enhances hepatitis B virus linkage to care among West African migrants in Spain Communications Medicine Picchio et al. report findings from a community-based hepatitis B virus (HBV) screening program for sub-Saharan African migrants in Catalonia Spain utilizing simplified testing and expedited referral to specialist care. Their findings support the adoption of these strategies to increase HBV testing and linkage to care among at-risk populations"
X Link 2024-01-15T08:00Z 208.1M followers, [---] engagements
"A 24-month National Cohort Study examining long-term effects of COVID-19 in children and young people Communications Medicine Stephenson Pinto Pereira et al. investigate the proportion of children and young people with Post Covid-19 condition 24-months post-infection. Only 7.2% meet the definition consistently at 3- 6- 12- and 24-months post-infection highlighting the importance of longitudinal studies"
X Link 2024-12-08T11:30Z 208.1M followers, [---] engagements
"Inhibiting anti-angiogenic VEGF165b activates a miR-17-20a-Calcipressin-3 pathway that revascularizes ischemic muscle in peripheral artery disease Communications Medicine Batan et al. show that inhibiting the antiangiogenic VEGF165b isoform activates a previously unrecognized miR-17-20a-RCAN3 pathway that induces ischemic endothelial cell angiogenic capacity and promotes M2-like macrophage polarization to achieve perfusion recovery in murine peripheral artery disease (PAD) model"
X Link 2024-02-16T12:00Z 208.1M followers, [--] engagements
"Evaluating variant pathogenicity prediction tools to establish African inclusive guidelines for germline genetic testing Communications Medicine Zhou et al. evaluate the predictive performance of [--] variant pathogenicity prediction tools using genomic data of advanced prostate cancer. MetaSVM CADD and Eigen-raw provide strong performance across ancestries while others like MutationTaster and DANN were African-specific with lower sensitivity for African data"
X Link 2025-05-19T22:15Z 208.1M followers, [--] engagements
"AAV9:PKP2 improves heart function and survival in a Pkp2-deficient mouse model of arrhythmogenic right ventricular cardiomyopathy Communications Medicine Wu Zeng et al. assess the feasibility and efficacy of AAV9:PKP2 gene therapy in the Pkp2-cKO mouse model of arrhythmogenic right ventricular cardiomyopathy. They show that it ameliorates ventricular arrhythmias reverses adverse right ventricular remodeling improves heart function and reduces mortality in this mouse model"
X Link 2024-03-26T14:00Z 208.1M followers, [---] engagements
"Targeted in vivo gene integration of a secretion-enabled GLP-1 receptor agonist reverses diet-induced non-genetic obesity and pre-diabetes Communications Medicine Hirose et al. demonstrate a genome editing-based strategy to treat obesity and pre-diabetes complex diseases without a defined genetic cause. A single in vivo knock-in of a secretion-engineered Exendin-4 gene into the liver enables sustained peptide release reducing body weight and improving glucose metabolism in mice"
X Link 2025-07-13T19:12Z 208.1M followers, [---] engagements
"Carotid body dysregulation contributes to Long COVID symptoms Communications Medicine El-Medany Adams Blythe et al. Investigate whether the carotid chemoreflex could be a mechanism underlying unexplained breathlessness in non-hospitalised patients with long COVID. Results show that carotid chemoreflex is sensitised in patients with long COVID and may explain dysregulated breathing and exercise intolerance in these participants"
X Link 2024-02-20T16:00Z 208.1M followers, [---] engagements
"Phenotypic and genomic characteristics of clinical IMP-producing Klebsiella spp. Isolates in China Communications Medicine Liu et al. analyze phenotypic and genomic characteristics of clinical IMP-producing Klebsiella spp. Isolates in China. Multi-clonal transmission multiple genetic environments and differing plasmid types all play a role in disseminating blaIMP genes among Klebsiella spp"
X Link 2024-02-27T07:00Z 208.1M followers, [---] engagements
"Low-calorie diets for people with isolated impaired fasting glucose Communications Medicine Thirunavukkarasu et al. discuss how standard lifestyle interventions prove ineffective in preventing type [--] diabetes in individuals with isolated impaired fasting glucose a highly prevalent prediabetes phenotype globally. They propose low-calorie diets as a promising strategy for diabetes prevention in this high-risk population"
X Link 2024-03-04T16:00Z 208.1M followers, [---] engagements
"A diffusion model for universal medical image enhancement Communications Medicine Fei Li Yang Gao et al. present UniMIE a training-free diffusion model for universal medical image enhancement without fine-tuning. It achieves high-quality results across [--] modalities and 15+ medical types using one ImageNet pre-trained model"
X Link 2025-08-08T11:37Z 208.1M followers, [--] engagements
"Machine learning-assisted assessment of extracellular vesicles can monitor cellular rejection after heart transplant Communications Medicine Burrello et al. combine extracellular vesicle profiling with adaptive artificial intelligence to monitor cell rejection after heart transplant. Heart transplant rejection is detected with high accuracy outperforming biopsy and anticipating rejection before histological signs offering a promising noninvasive tool for timely intervention and personalized monitoring"
X Link 2025-08-07T16:35Z 208.1M followers, [--] engagements
"Childhood predictors of suffering in adulthood across [--] countries Communications Medicine Cowden et al. use nationally representative data from [--] countries included in Wave [--] of the Global Flourishing Study to explore associations of individual characteristics and retrospectively recalled childhood factors with suffering in adulthood. A combination of risk and protective factors during childhood may be associated with suffering in adulthood"
X Link 2025-06-25T12:02Z 208.1M followers, [--] engagements
"A multidimensional network of factors associated with long COVID in the French population Communications Medicine Coste et al. survey factors potentially associated with long COVID in [----] adults in France. A broad spectrum of medical psychological and social factors are found to be associated with an increased risk of developing long COVID"
X Link 2025-04-14T12:23Z 208.1M followers, [--] engagements
"Considering clonal hematopoiesis of indeterminate potential in space radiation risk analysis for hematologic cancers and cardiovascular disease Communications Medicine Werneth et al. evaluate the impact of clonal hematopoiesis of indeterminate potential (CHIP) on health risks associated with space radiation exposures in astronauts. This work highlights the importance of considering personalized risk factors such as CHIP for effective risk assessment and monitoring of astronaut health"
X Link 2024-06-20T14:00Z 208.1M followers, [---] engagements
"Detection of COVID-19 features in lung ultrasound images using deep neural networks Communications Medicine Zhao et al. investigate optimal strategies to detect COVID-19 features in lung ultrasound images using deep neural networks trained with simulated and in vivo datasets. Including simulated data during training improves detection performance and training efficiency and is a promising alternative to curating thousands of patient images"
X Link 2024-03-13T17:00Z 208.1M followers, [---] engagements
"Generalisable deep learning method for mammographic density prediction across imaging techniques and self-reported race Communications Medicine Khara et al perform a comprehensive performance analysis for a deep learning breast density prediction model using a large scale racially diverse dataset. They find that the model generalises across imaging techniques and self-reported race providing assurances for the safe and ethical use of automated breast density prediction"
X Link 2024-02-20T12:00Z 208.1M followers, [---] engagements
"Feasibility of serial measurement of nitrite for pharmacodynamic monitoring and precision prescribing in urinary tract infections Communications Medicine Stadler et al. evaluate the diagnostic value of urinary tract infection biomarker nitrite in predicting disease progression and treatment efficacy. The longitudinal measurement of nitrite in an in-vitro UTI distinguishes between amoxicillin-resistant and susceptible E. coli strains and correlates with bacterial colony-forming unit counts in-vitro and in clinical UTI"
X Link 2025-07-29T11:31Z 208.1M followers, [---] engagements
"Concurrent gliomas in patients with multiple sclerosis Communications Medicine Sahm et al. evaluate clinical imaging and molecular data from a small cohort of patients with concurrent multiple sclerosis (MS) and gliomas. They report differential methylation of some immune-related loci in tumors from patients with MS and that inflammatory disease activity can increase in these patients after brain tumor radiotherapy"
X Link 2024-01-17T17:00Z 208.1M followers, [---] engagements
"N-glycan-modified -L-iduronidase produced by transgenic silkworms ameliorates clinical signs in a Japanese macaque with mucopolysaccharidosis I Communications Medicine Shinoda and Kitakaze et al. prepared recombinant hIDUA from transgenic silkworm cocoons and transglycosylated to mannose-6-phosphate- or α26-sialyl glycan-type using ENGases. These enzymes were administrated to a mucopolysaccharidosis type I macaque and succeeded in improving the clinical signs and reducing the urinary glycosaminoglycan levels"
X Link 2025-05-08T12:32Z 208.1M followers, [---] engagements
"Household-level effects of seasonal malaria chemoprevention in the Gambia Communications Medicine Soremekun et al. report the impact of extending seasonal malaria chemoprevention (SMC) to children aged [--] years on malaria transmission in the context of a national routine programme. This SMC extension to older children reduces the risk of clinical malaria and asymptomatic infection among adolescents and adults within the same household"
X Link 2024-05-31T15:00Z [----] followers, [---] engagements
"A bibliometric analysis of the gender gap in the authorship of leading medical journals Communications Medicine Brück observes a decrease in the gender gap in the authorship of leading medical journals between [----] and [----] with some country-specific variation. This study provides a model approach for tracking gender representation in academic research"
X Link 2024-01-09T12:00Z 208.1M followers, [--] engagements
"Altered mitochondrial function in fibroblast cell lines derived from disease carriers of spinal muscular atrophy Communications Medicine James et al. compare mitochondrial function in fibroblast cell lines from disease carriers of spinal muscular atrophy (SMA) and control individuals. They report altered mitochondrial activity in SMA carriers suggesting that carriers have a subclinical mitochondrial phenotype"
X Link 2024-05-20T10:30Z 208.1M followers, [---] engagements
"A CD25-biased interleukin-2 for autoimmune therapy engineered via a semi-synthetic organism Communications Medicine Ptacin et al. utilize a semi-synthetic microbial platform with an expanded genetic code to discover a PEGylated IL-2 compound that stimulates Tregs with minimal effects on effector populations. Studies in mice and primates demonstrate Treg stimulation and support development of this compound for the potential treatment of autoimmune diseases"
X Link 2024-04-08T14:00Z 228.6M followers, [----] engagements
"Substantial but spatially heterogeneous progress in male circumcision for HIV prevention in South Africa Communications Medicine Thomas et al. present a model that integrates household survey and health system data to estimate subnational circumcision coverage in South Africa during scale-up for HIV prevention. Results show considerable but heterogenous progress towards increasing circumcision coverage identifying priority ages and districts to reach national targets"
X Link 2024-02-02T07:00Z 208.1M followers, [---] engagements
"A roadmap for genome projects to foster psychosocial and economic evidence to further policy and practice Communications Medicine Chung et al. examine the multi-dimensional effectiveness of genome sequencing and summarise indicators and measurement tools for psychosocial and economic outcomes. They highlight priority areas for outcome-oriented research and showcase best practices in selecting outcome measures for effective implementation within genome projects"
X Link 2025-06-18T09:01Z 208.1M followers, [---] engagements
"Comprehensive testing of large language models for extraction of structured data in pathology Communications Medicine Grothey et al. examine the performance of large language models in structuring pathology reports. Findings demonstrate similar accuracy between commercial and open-source models providing a cost-effective privacy-conscious solution to extract structured data with high precision from bilingual datasets"
X Link 2025-04-23T12:01Z 208.1M followers, [--] engagements
"Serum autotaxin is a prognostic indicator of liver-related events in patients with non-alcoholic fatty liver disease Communications Medicine Iwadare et al. investigate the value of serum autotaxin levels in predicting liver-related events within a retrospective cohort of [---] biopsy-proven NAFLD patients. Multivariate Cox proportional hazards models identify autotaxin levels and advanced fibrosis as independent predictive factors"
X Link 2024-05-14T07:00Z 208.1M followers, [---] engagements
"Evaluation of a large language model to simplify discharge summaries and provide cardiological lifestyle recommendations Communications Medicine Rust et al. evaluate a large language model to simplify cardiology discharge summaries and provide lifestyle recommendations. Findings show improved readability while maintaining medical accuracy as well as relevant but not sufficiently personalized lifestyle recommendations"
X Link 2025-06-23T12:31Z 208.1M followers, [--] engagements
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