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[@BPharmCatalyst](/creator/twitter/BPharmCatalyst)
"$SHPH signed a letter of intent to acquire for $10M in cash and stock adding an AI-driven drug discovery platform that accelerates candidate identification and integrates autonomous workflows to enhance Shuttles therapeutic development capabilities. $SHPH $CARM $ARAY $CDT $ATYR $CDTX $ADTX $LITS $IVA $KIDS See More Pre-market Movers"  
[X Link](https://x.com/BPharmCatalyst/status/1976628859224154616) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-10T12:40Z 30.4K followers, 1657 engagements


"$GNPX announced preclinical data showing its lead candidate Reqorsa (quaratusugene ozeplasmid) induced apoptosis and demonstrated strong efficacy in ALK-EML4positive non-small cell lung cancer models. The data to be presented at the AACR-NCI-EORTC Molecular Targets Conference support Reqorsas potential as a gene therapy targeting the TUSC2 tumor suppressor pathway and its use in combination with ALK inhibitors. $GNPX $SCYX $KROS $EYPT $SPRC $EVAX $DMAC $IOBT $ELAB $ENTX See More Pre-market Movers"  
[X Link](https://x.com/BPharmCatalyst/status/1978440788246724827) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-15T12:40Z 30.4K followers, 12.5K engagements


"$SPRB shares closed up after the FDA granted Breakthrough Therapy designation to tralesinidase alfa for Sanfilippo Syndrome Type B a rare pediatric neurodegenerative disorder. The company plans to file for U.S. approval in the first quarter of 2026. $SPRB $BMEA $HUMA $TELO $LXEO $LPTX $GLTO $XBIO $EVAX $CLRB See More Biotech Updates👇"  
[X Link](https://x.com/BPharmCatalyst/status/1975660419827028191) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-07T20:32Z 30.4K followers, 2266 engagements


"BioPharmCatalyst Weekly #Watchlist BioPharmCatalyst Weekly Watchlist: Key PDUFA and regulatory catalysts for the next X months $COGT $RZLT $DVBT $BLTE $MBRX $IMVT $PCVX $BCTX $KALV $CGEM"  
[X Link](https://x.com/BPharmCatalyst/status/1977016053541879867) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-11T14:18Z 30.4K followers, 1934 engagements


"$RAPP announced that its lead candidate RAP-219 met primary and key secondary endpoints in a Phase 2a trial for drug-resistant focal onset seizures demonstrating a XXXX% median seizure reduction and XX% seizure freedom with strong safety and tolerability. $DNTH $SMMT $IDYA $SINT $EDAP $XAIR See More Pre-market Movers"  
[X Link](https://x.com/BPharmCatalyst/status/1965032454596497564) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-09-08T12:40Z 30.4K followers, 3569 engagements


"$EVAX will present new biomarker and immune data for its personalized cancer vaccine EVX-01 in advanced melanoma at SITC 2025 complementing upcoming two-year efficacy results from its Phase X KEYTRUDA combination trial being presented at ESMO 2025. $PALI $ANRO $OVID $IMAB $BOLT $EVAX $APLIF $CLNN $SPRC $OCEA See More Biotech Updates👇"  
[X Link](https://x.com/BPharmCatalyst/status/1974210485022085549) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-03T20:30Z 30.4K followers, 3413 engagements


"$CDT announced a 1-for-8 reverse stock split approved by its board aiming to enhance capital-raising flexibility as part of its strategic execution following prior shareholder authorization granted in May 2025. $BJDX $CDT $AKRO $APGE $ATHE $NGNE $TCRT $BDRX $PCSA $GTBP See More Pre-market Movers"  
[X Link](https://x.com/BPharmCatalyst/status/1976266478425915437) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-09T12:40Z 30.4K followers, 1966 engagements


"$NDRA secured $XXX million in a private placement led by institutional and crypto investors selling stock and warrants at $XXXX per unit to fund a digital asset treasury strategy focused on Arcas high-conviction DeFi holdings marking a pivot toward blockchain-linked capital deployment alongside its core MASLD/MASH imaging focus. $TRVD $CGEN $RCUS $MNPR $NDRA $SRRK $NBTX $APLT $QNRX $ADTX See More Biotech Updates👇"  
[X Link](https://x.com/BPharmCatalyst/status/1977834368639832089) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-13T20:30Z 30.4K followers, 1935 engagements


"$BCRX and $ATXS announced that the companies have entered into a definitive agreement under which BioCryst has agreed to acquire Astria a biopharmaceutical company focused on developing life-changing therapies for allergic and immunologic diseases for a mix of cash and stock representing an implied value of $XXXXX per Astria share and approximately $XXX million in enterprise value. $ATXS $IPHA $NDRA $RCKT $SBFM $GDTC $ELAB $GNPX $NBTX $DBVT See More Pre-market Movers"  
[X Link](https://x.com/BPharmCatalyst/status/1978078417846149238) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-14T12:40Z 30.4K followers, 1971 engagements


"$OMER signed a definitive agreement to sell global rights of its MASP-3 inhibitor zaltenibart (OMS906) to Novo Nordisk for $340M upfront and near-term milestones with total deal value up to $2.1B plus tiered royalties giving Novo full control over development and commercialization in rare blood and kidney disorders. $GNPX $OMER $SPRC $EVAX $ENVB $SBFM $TOVX $SANA $AKTX $GANX See More Biotech Updates👇"  
[X Link](https://x.com/BPharmCatalyst/status/1978560064437825681) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-15T20:34Z 30.4K followers, 2096 engagements


"$GNPX announced preclinical data showing its lead candidate Reqorsa (quaratusugene ozeplasmid) induced apoptosis and demonstrated strong efficacy in ALK-EML4positive non-small cell lung cancer models. $GNPX $ATXS $NDRA $RCKT $GDTC $SBFM $EVAX $SNTI $CERO $IVVD See More Biotech Updates👇"  
[X Link](https://x.com/BPharmCatalyst/status/1978197105635143722) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-14T20:31Z 30.4K followers, 3442 engagements


"$ELUT agreed to sell its cardiac device business to Boston Scientific for $88M enabling debt elimination and a strategic shift toward its breast reconstruction-focused SimpliDerm franchise and drug-eluting pipeline aiming to improve financial stability and preserve shareholder value without dilution. $TRML $ELUT $CELU $RENB $REVB $TELO $XLO See More Biotech Updates👇 link"  
[X Link](https://x.com/BPharmCatalyst/status/1965513150960119968) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-09-09T20:30Z 30.4K followers, 1885 engagements


"$RANI signed a $1.085B potential collaboration with Chugai receiving $10M upfront and up to $175M in milestones and royalties for the lead oral biologic using its RaniPill platform; alongside a $60.3M oversubscribed private placement and $28M in expected Chugai payments Rani is now funded into 2028 to advance its oral biologics pipeline. $RANI $ARTV $XRTX $KZR $ACHV $PLX $AKAN $IRON $RCEL $NIVF See More Pre-market Movers"  
[X Link](https://x.com/BPharmCatalyst/status/1979165574019068232) [@BPharmCatalyst](/creator/x/BPharmCatalyst) 2025-10-17T12:40Z 30.4K followers, 1684 engagements