[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

[@bmj_rmdopen](/creator/twitter/bmj_rmdopen)
"Metabolomics in #LupusNephritis in TULIP-LN #SLE ✅ #Anifrolumab (intensive regimen) lowered: Serum indoxyl sulfate (uremic toxin) & cytosine Urine uracil & cytosine 🔎 Baseline Indoxyl sulfate worse kidney metrics (creatinine eGFR) Urine pyrimidines IFN gene signature SLEDAI anti-dsDNA Urine uracil predicted alternative CRR at Week XX (AUC 0.82) 🧬 Anifrolumab blunted IS-induced VCAM1/IL-6 in glomerular ECs in vitro 💡 Points to an IFNpyrimidineuremic toxin axis and a potential urinary marker to guide therapy"  
[X Link](https://x.com/bmj_rmdopen/status/1980617595578450005) [@bmj_rmdopen](/creator/x/bmj_rmdopen) 2025-10-21T12:50Z XXX followers, XXX engagements


"🎻 RMDs in musicians: risks adaptations & care 🎹 ✅ Performance-impairing MSK complaints reported by 6476% of players 🎯 High-risk patterns: tendinopathies entrapment syndromes (carpal/cubital) CMC OA rotator cuff thoracic outlet TMJ 🧩 Instrument-specific loads (strings/winds upper limb/shoulder; percussion drummers wrist) ⚠ Dystonia = major concern in professional musicians 🤸♂ Hypermobility can help dexterity but destabilises support joints 🛠 Prevention/management: posture & ergonomics graded loading frequent breaks early referral to arts-medicine clinics 🔓"  
[X Link](https://x.com/bmj_rmdopen/status/1982022073074549188) [@bmj_rmdopen](/creator/x/bmj_rmdopen) 2025-10-25T09:51Z XXX followers, XXX engagements