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[@SashaGusevPosts](/creator/twitter/SashaGusevPosts)
"@how_now00 Yeah it's actually incredible they can even do PRS/GWAS with this data. The low quality is also why they mostly rely on F statistics and don't do fancier haplotype-based models (though that's changing with new IBD methods)"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1945995267469103283) 2025-07-17 23:53:21 UTC 19.1K followers, XXX engagements


"A: Another one with perfect SATs but low GPAs. He skipped class to build a healthcare startup that got acquired by Merck. Wants to major in business. P: Fine we can take exceptional outliers. But just the obvious ones along their clearly intended majors. We are NOT holistic"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946626778069365203) 2025-07-19 17:42:45 UTC 19.1K followers, 22.7K engagements


"@AnaerobicLagoon I think this is more or less how it works but people take SATs and subject specific SAT2s at the same time and then other non-test strengths are considered"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946674506208088166) 2025-07-19 20:52:24 UTC 19.1K followers, 10.3K engagements


"@Gustavo21239788 So I guess we're rejecting brilliant athletes writers artists startup founders etc. or people who have stellar grades but don't test well"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946652308206403956) 2025-07-19 19:24:11 UTC 19.1K followers, 6984 engagements


"@7uomoki Yeah I can definitely see this working with human input spotting challenges or nudging it in the right direction. But hard to imagine how it would work with the LLM re-evaluating itself without any additional external info"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946789545082581382) 2025-07-20 04:29:31 UTC 19.1K followers, XXX engagements


"In fact IQ tests are heavily biased towards culturally dependent tasks: "g loading" correlates almost perfectly with an objective measure of culture dependence. These are also the tests that exhibit the largest racial differences and "heritability""  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1932792606380998674) 2025-06-11 13:30:41 UTC 19.1K followers, 41.8K engagements


"I'm puzzled by the proposal in this piece that political leaders start talking more about ideological sorting. For one it's not clear what talking is supposed to accomplish. For two Congress is far more despised than the "expert" institutions (higher ed / medicine)"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1945866583005380916) 2025-07-17 15:22:00 UTC 19.1K followers, 3917 engagements


"@wil_da_beast630 And AA is now illegal with this administration going after putative violations more aggressively than any other corporate malfeasance in the country. Yet people seem angrier than ever"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946635429425348950) 2025-07-19 18:17:07 UTC 19.1K followers, 2963 engagements


"A: One applicant has perfect SATs but middling grades because she exposed a bribery ring at his school and all the teachers retaliated. It was in The New York Times. P: . I guess we should make an exception for clear mitigating circumstances like that"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946626776647524389) 2025-07-19 17:42:44 UTC 19.1K followers, 24.5K engagements


"Has there been any quantification of if/when serial prompting an LLM ("Write this code" then "Review what you wrote for bugs") is more accurate than single prompt ("Write this code avoid bugs") Likewise for asking the LLM to first optimize your prompt"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946785640403665086) 2025-07-20 04:14:00 UTC 19.1K followers, 2605 engagements


"So everything hangs together nicely: schooling reliably increases IQ IQ measures a major component of acculturation through schooling and there are massive differences in schooling and neighborhood quality in the US. /fin"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1932792608377745496) 2025-06-11 13:30:42 UTC 19.1K followers, 60.8K engagements


"Both my wife and I attended decent state schools (UMass and UConn) had a great time and developed the skills to pursue careers we enjoy. I highly recommend it Yet people still seem to both hate and envy elite admissions for reasons I don't really understand"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946296170105475471) 2025-07-18 19:49:02 UTC 19.1K followers, 2989 engagements


"Will is understating the case here. In the past year alone the author (Rindermann) had a paper retracted because it featured bizarre examples from his own life and another paper in the Journal of Controversial Ideas with blatant analysis errors. Garbage in racism out"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1945184125251375261) 2025-07-15 18:10:09 UTC 19.1K followers, 42.4K engagements


"@i000 @ladanuzhna Yeah and MRD is a huge industry though IMO still in the "potential impact" stage for most cancers (e.g. LDT but not full FDA approval)"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946620538459164842) 2025-07-19 17:17:57 UTC 19.1K followers, XX engagements


". classes and are experiencing a collective mental breakdown. Also our sports teams are an embarrassment. P: Okay admit some athletes with good but not excellent grades but ONLY if theyre state champions. We'll kill two birds with one stone while staying objective"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946626772344136092) 2025-07-19 17:42:43 UTC 19.1K followers, 30.5K engagements


"@ladanuzhna Tumor sequencing is now standard of care for multiple cancers to identify targetable drivers and for TMB/immunotherapy at certain stages. Germline cascade screening is recommended for breast/ovarian cancer and syndromes"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946616836524564542) 2025-07-19 17:03:14 UTC 19.1K followers, XXX engagements


"*Open: Office of the president at the new XXX% Meritocratic University* President: Weve admitted the top 2000 applicants by GPA and SATs. How are they doing Admissions: Several hundred valedictorians whove never gotten a B in their life are now at the bottom of all their"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946626770771300842) 2025-07-19 17:42:43 UTC 19.1K followers, 219.4K engagements


"Oof. Polygenic scores for IQ lose XX% of their explained variance when adding family controls even worse than the attenuation for Educational Attainment. These are the scores Silicon Valley is using to select embryos 😬. A few thoughts on this study"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1937335235437285759) 2025-06-24 02:21:28 UTC 19.1K followers, 967.1K engagements


"@how_now00 @mirrorreversed 4) Can't be power: the EASEA PGS was a better predictor than the EUREA PGS in the Chen et al. paper. Also see the strong PGS_SCZ/IQ relationship below (stronger than either PGS_IQ/IQ or PGS_EA/IQ) probably another epicycle for this one"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1943488530442826046) 2025-07-11 01:52:28 UTC 19.1K followers, XXX engagements


"A: The international youth playwright awardee that just got rejected because of their average SAT math score is on line one. P: Alright alright well allow exceptional liberal arts achievements. But they have to be truly exceptional: national awards bestsellers etc"  
![@SashaGusevPosts Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::1610136398874525698.png) [@SashaGusevPosts](/creator/x/SashaGusevPosts) on [X](/post/tweet/1946626775192138098) 2025-07-19 17:42:44 UTC 19.1K followers, 26.5K engagements

[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]

@SashaGusevPosts "@how_now00 Yeah it's actually incredible they can even do PRS/GWAS with this data. The low quality is also why they mostly rely on F statistics and don't do fancier haplotype-based models (though that's changing with new IBD methods)"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-17 23:53:21 UTC 19.1K followers, XXX engagements

"A: Another one with perfect SATs but low GPAs. He skipped class to build a healthcare startup that got acquired by Merck. Wants to major in business. P: Fine we can take exceptional outliers. But just the obvious ones along their clearly intended majors. We are NOT holistic"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:42:45 UTC 19.1K followers, 22.7K engagements

"@AnaerobicLagoon I think this is more or less how it works but people take SATs and subject specific SAT2s at the same time and then other non-test strengths are considered"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 20:52:24 UTC 19.1K followers, 10.3K engagements

"@Gustavo21239788 So I guess we're rejecting brilliant athletes writers artists startup founders etc. or people who have stellar grades but don't test well"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 19:24:11 UTC 19.1K followers, 6984 engagements

"@7uomoki Yeah I can definitely see this working with human input spotting challenges or nudging it in the right direction. But hard to imagine how it would work with the LLM re-evaluating itself without any additional external info"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-20 04:29:31 UTC 19.1K followers, XXX engagements

"In fact IQ tests are heavily biased towards culturally dependent tasks: "g loading" correlates almost perfectly with an objective measure of culture dependence. These are also the tests that exhibit the largest racial differences and "heritability""
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-06-11 13:30:41 UTC 19.1K followers, 41.8K engagements

"I'm puzzled by the proposal in this piece that political leaders start talking more about ideological sorting. For one it's not clear what talking is supposed to accomplish. For two Congress is far more despised than the "expert" institutions (higher ed / medicine)"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-17 15:22:00 UTC 19.1K followers, 3917 engagements

"@wil_da_beast630 And AA is now illegal with this administration going after putative violations more aggressively than any other corporate malfeasance in the country. Yet people seem angrier than ever"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 18:17:07 UTC 19.1K followers, 2963 engagements

"A: One applicant has perfect SATs but middling grades because she exposed a bribery ring at his school and all the teachers retaliated. It was in The New York Times. P: . I guess we should make an exception for clear mitigating circumstances like that"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:42:44 UTC 19.1K followers, 24.5K engagements

"Has there been any quantification of if/when serial prompting an LLM ("Write this code" then "Review what you wrote for bugs") is more accurate than single prompt ("Write this code avoid bugs") Likewise for asking the LLM to first optimize your prompt"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-20 04:14:00 UTC 19.1K followers, 2605 engagements

"So everything hangs together nicely: schooling reliably increases IQ IQ measures a major component of acculturation through schooling and there are massive differences in schooling and neighborhood quality in the US. /fin"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-06-11 13:30:42 UTC 19.1K followers, 60.8K engagements

"Both my wife and I attended decent state schools (UMass and UConn) had a great time and developed the skills to pursue careers we enjoy. I highly recommend it Yet people still seem to both hate and envy elite admissions for reasons I don't really understand"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-18 19:49:02 UTC 19.1K followers, 2989 engagements

"Will is understating the case here. In the past year alone the author (Rindermann) had a paper retracted because it featured bizarre examples from his own life and another paper in the Journal of Controversial Ideas with blatant analysis errors. Garbage in racism out"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-15 18:10:09 UTC 19.1K followers, 42.4K engagements

"@i000 @ladanuzhna Yeah and MRD is a huge industry though IMO still in the "potential impact" stage for most cancers (e.g. LDT but not full FDA approval)"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:17:57 UTC 19.1K followers, XX engagements

". classes and are experiencing a collective mental breakdown. Also our sports teams are an embarrassment. P: Okay admit some athletes with good but not excellent grades but ONLY if theyre state champions. We'll kill two birds with one stone while staying objective"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:42:43 UTC 19.1K followers, 30.5K engagements

"@ladanuzhna Tumor sequencing is now standard of care for multiple cancers to identify targetable drivers and for TMB/immunotherapy at certain stages. Germline cascade screening is recommended for breast/ovarian cancer and syndromes"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:03:14 UTC 19.1K followers, XXX engagements

"Open: Office of the president at the new XXX% Meritocratic University President: Weve admitted the top 2000 applicants by GPA and SATs. How are they doing Admissions: Several hundred valedictorians whove never gotten a B in their life are now at the bottom of all their"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:42:43 UTC 19.1K followers, 219.4K engagements

"Oof. Polygenic scores for IQ lose XX% of their explained variance when adding family controls even worse than the attenuation for Educational Attainment. These are the scores Silicon Valley is using to select embryos 😬. A few thoughts on this study"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-06-24 02:21:28 UTC 19.1K followers, 967.1K engagements

"@how_now00 @mirrorreversed 4) Can't be power: the EASEA PGS was a better predictor than the EUREA PGS in the Chen et al. paper. Also see the strong PGS_SCZ/IQ relationship below (stronger than either PGS_IQ/IQ or PGS_EA/IQ) probably another epicycle for this one"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-11 01:52:28 UTC 19.1K followers, XXX engagements

"A: The international youth playwright awardee that just got rejected because of their average SAT math score is on line one. P: Alright alright well allow exceptional liberal arts achievements. But they have to be truly exceptional: national awards bestsellers etc"
@SashaGusevPosts Avatar @SashaGusevPosts on X 2025-07-19 17:42:44 UTC 19.1K followers, 26.5K engagements

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/creator/twitter::1610136398874525698/posts