#  @kinatsofrim @KinatSofrim @KinatSofrim posts on X about $kpti, $incy, $nvs, ceo the most. They currently have [---] followers and [---] posts still getting attention that total [-----] engagements in the last [--] hours. ### Engagements: [-----] [#](/creator/twitter::1243636820295942144/interactions)  - [--] Week [-----] +71% - [--] Month [------] +30% - [--] Months [------] +11% - [--] Year [-------] -34% ### Mentions: [--] [#](/creator/twitter::1243636820295942144/posts_active)  - [--] Week [--] +57% - [--] Month [--] +40% - [--] Months [---] +35% - [--] Year [---] -17% ### Followers: [---] [#](/creator/twitter::1243636820295942144/followers)  - [--] Week [---] +0.35% - [--] Month [---] +0.58% - [--] Months [---] +3.70% - [--] Year [---] +16% ### CreatorRank: [---------] [#](/creator/twitter::1243636820295942144/influencer_rank)  ### Social Influence **Social category influence** [stocks](/list/stocks) 21.24% [finance](/list/finance) 4.42% [countries](/list/countries) 3.54% [currencies](/list/currencies) 1.77% [cryptocurrencies](/list/cryptocurrencies) 1.77% [automotive brands](/list/automotive-brands) 0.88% [travel destinations](/list/travel-destinations) 0.88% [musicians](/list/musicians) 0.88% [celebrities](/list/celebrities) 0.88% **Social topic influence** [$kpti](/topic/$kpti) #2, [$incy](/topic/$incy) #4, [$nvs](/topic/$nvs) #10, [ceo](/topic/ceo) 7.96%, [$gsk](/topic/$gsk) #7, [in the](/topic/in-the) 6.19%, [$gsks](/topic/$gsks) #1, [$kptis](/topic/$kptis) #1, [pi](/topic/pi) 3.54%, [$incys](/topic/$incys) #1 **Top accounts mentioned or mentioned by** [@harrisoncn1](/creator/undefined) [@raajitrampal](/creator/undefined) [@bloodcancers](/creator/undefined) [@boseprithviraj](/creator/undefined) [@petermpn](/creator/undefined) [@kartosthera](/creator/undefined) [@buysidebio](/creator/undefined) [@biopharmaddict](/creator/undefined) [@doctorpemm](/creator/undefined) [@taniajain11](/creator/undefined) [@medscape](/creator/undefined) [@vasnarasimhan](/creator/undefined) [@bymadeleinea](/creator/undefined) [@antengene](/creator/undefined) [@mdmasarova](/creator/undefined) [@clinadvances](/creator/undefined) [@mkremyanskaya](/creator/undefined) [@doclucchesi](/creator/undefined) [@erictokat](/creator/undefined) [@icahnmountsinai](/creator/undefined) **Top assets mentioned** [Incyte Corporation (INCY)](/topic/$incy) [Novartis AG (NVS)](/topic/$nvs) [GSK plc (GSK)](/topic/$gsk) [Merck & Co., Inc. (MRK)](/topic/$mrk) [Geron Corp (GERN)](/topic/$gern) [AbbVie Inc (ABBV)](/topic/$abbv) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [AstraZeneca PLC (AZN)](/topic/$azn) [One Cash (ONC)](/topic/$onc) [Frontline Ltd. (FRO)](/topic/$fro) [Amgen, Inc. (AMGN)](/topic/$amgn) [Royalty Pharma plc (RPRX)](/topic/$rprx) [Legend Biotech Corp (LEGN)](/topic/$legn) ### Top Social Posts Top posts by engagements in the last [--] hours "@BaldwynKing @EladStr @JasonMBrodsky @biannagolodryga Theyre very influential people. they control media - If you think by theyre/they he meant Israel then I agree youre not just playing dumb" [X Link](https://x.com/anyuser/status/1395479729709408258) 2021-05-20T20:41Z [---] followers, [--] engagements "PSA for those beginning mas. Taanit tomorrow: Dont get overly pedantic with Rashi (especially not s) more than you would with any other Rishon; cf. referenced literature in the note below:" [X Link](https://x.com/kinatsofrim/status/1459709339153973250) 2021-11-14T02:26Z [---] followers, [--] engagements "A very welcome reprint. As all of R Yaacov Haim Sofers books are packed with content of all sorts (he has great tangents π€) this set has now been reprinted with a very valuable index (for all 12vols) and some other minor corrections" [X Link](https://x.com/kinatsofrim/status/1555368284081594368) 2022-08-05T01:41Z [---] followers, [--] engagements "I guess the anonymous author included this for posterity:" [X Link](https://x.com/anyuser/status/1561879091606953984) 2022-08-23T00:52Z [---] followers, [--] engagements "@ayilbasvach She clearly follows the Rama to make the Bracha after we light and not like the Mechaber to make the Bracha before " [X Link](https://x.com/kinatsofrim/status/1562262922231005185) 2022-08-24T02:18Z [---] followers, [--] engagements "PSA to all Yoel's out there. When you go into the workforce you don't need to automatically become a Joel Yoel Roth @yoyoel" [X Link](https://x.com/kinatsofrim/status/1587797459786498049) 2022-11-02T13:23Z [---] followers, [--] engagements "@Yahrtzeits [--] Cheshvon: R' Moshe (b. Yosef) Levi (1961-2000). Greatly influnetial posek & dedicated Rosh Mesivta in Kisse Rahamim. Authored famous seforim on Shabbat (Menuhat Ahavah) usery (Malveh Hashem) blessings (Birkat Hashem) responsa and more" [X Link](https://x.com/anyuser/status/1588558347351257088) 2022-11-04T15:46Z [---] followers, [--] engagements "@endimem_music Lashon hara CC Heritage Foundation β Talking in shul Stopthetalking. org β Tznius Vaad Mishmeres Haznius β Internet TAG β Tithe giving @kupat_hair β Shmiras einayim Young Balabatim Players β Do things le'shem shamayim Untapped market" [X Link](https://x.com/kinatsofrim/status/1595948803223617536) 2022-11-25T01:13Z [---] followers, [--] engagements "In time for his @Yahrtzeits [--] Shvat: (1928-2021) New ' on the life of the Tzaddik R' Binyamin Cohen of Moshav Berechya. Rav Shach in the 70's said he's a . Rav Schwadron after spending shabbasim in his house in Berechhya said he was one of the " tzaddikim" [X Link](https://x.com/kinatsofrim/status/1623773197383438336) 2023-02-09T19:57Z [---] followers, [----] engagements "7 Nissan @Yahrtzeits Mekubal Rav Sasson Mizrahi (1913-1998) author of Basi LeGani on the Etz Hayyim" [X Link](https://x.com/kinatsofrim/status/1640901187925954562) 2023-03-29T02:18Z [---] followers, [----] engagements "8 Teves @Yahrtzeits: Rav Yitzchak Assabag (1888-1971) Dayan and Rosh Yeshiva in Meknes Morocco" [X Link](https://x.com/kinatsofrim/status/1737296956760670567) 2023-12-20T02:20Z [---] followers, [----] engagements "11 Teves @Yahrtzeits: Mekubal R' Yehoshua Sharabani of Baghdad Iraq;later on a Rav of Baka Jerusalem; premier student of the Ben Ish Chai (1872-1972)" [X Link](https://x.com/kinatsofrim/status/1738260491783270858) 2023-12-22T18:09Z [---] followers, [----] engagements "$KPTI $INCY $NVS $GSK h/t @pec_panco_Alex /48 https://x.com/kinatsofrim/status/1754123089904861511 @777archie @doepke_michel Pelabresib ($MOR) failed TSS50 in P3. Navitoclax ($ABBV) failed TSS50 in P3. Navtemadlin (Kartos) both SVR & TSS50 SS were in the 30's. Imetelstat ($GERN) SA; SVR 10+% and TSS50 low 30's. It's not hard to see $KPTI competitiveness at this point. @IloveIncyte @AlbertBourla https://x.com/kinatsofrim/status/1754123089904861511 @777archie @doepke_michel Pelabresib ($MOR) failed TSS50 in P3. Navitoclax ($ABBV) failed TSS50 in P3. Navtemadlin (Kartos) both SVR & TSS50 SS were" [X Link](https://x.com/kinatsofrim/status/1824177604863332354) 2024-08-15T20:13Z [---] followers, [---] engagements "FDA to PharmaEssentia "symptom score (TSS50) will be a required co-primary endpoint" $NVS $INCY $KPTI $GSK $ABBV @adamfeuerstein /49" [X Link](https://x.com/kinatsofrim/status/1824281739998490982) 2024-08-16T03:07Z [---] followers, [---] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive $KPTI Thank you @bose_prithviraj h/t @Blood_Cancers $NVS's pelabresib failed both absolute TSS reduction and TSS50 $INCY it's time to act. /303 https://x.com/kinatsofrim/status/1852014483847209241s=20" [X Link](https://x.com/kinatsofrim/status/1996397684153029055) 2025-12-04T01:54Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict $KPTI Thank you Dr. @bose_prithviraj Dr. Nikolai Podoltsev @YaleCancer h/t @Blood_Cancers SENTRY & SENTRY-2 /320 https://www.bloodcancerstoday.com/post/six-things-the-2025-sentry-study-data-tell-us-about-the-future-of-myelofibrosis https://www.bloodcancerstoday.com/post/six-things-the-2025-sentry-study-data-tell-us-about-the-future-of-myelofibrosis" [X Link](https://x.com/kinatsofrim/status/2006448923683205453) 2025-12-31T19:34Z [---] followers, [---] engagements "@komatinskys @harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal Notably missing $GERN $BMY Kartos & PharmaEssentia" [X Link](https://x.com/kinatsofrim/status/2015542873064694202) 2026-01-25T21:50Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $NVS confirm they'll need start new phase [--] for bet inhibitor pelabresib. $KPTI /328 https://x.com/kinatsofrim/status/2015810326365679758s=20 @harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal $NVS will have to start new P3 for pelabresib Manifest-3 h/t @ByMadeleineA https://t.co/GHRHybWNYI /324 https://t.co/3cMZfstdkF https://x.com/kinatsofrim/status/2015810326365679758s=20 @harrisoncn1 @peter_mpn @KartosThera" [X Link](https://x.com/kinatsofrim/status/2019101429948907932) 2026-02-04T17:31Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $KPTI /331 https://x.com/kinatsofrim/status/1977773684640350246s=20 @komatinskys @jfais20 $KPTI Investigators were compelled & wowed by the [---] data (heavily pre treated population) especially the IL-8 disease modification cytokines. https://t.co/iWxsTUpGLk https://x.com/kinatsofrim/status/1977773684640350246s=20 @komatinskys @jfais20 $KPTI Investigators were compelled & wowed by the [---] data (heavily pre treated population) especially the IL-8 disease modification" [X Link](https://x.com/kinatsofrim/status/2019807592374292944) 2026-02-06T16:17Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $KPTI just in MF alone. /332 https://x.com/kinatsofrim/status/1859619451772998019s=20 @VasNarasimhan Now that $NVS pelabresib is officially dead $KPTI forecast of $1b sales is extremely low given the fact $INCY Rux sales $2.2b for half the efficacy 30% drop off opposed to the efficacy durability data of Seli which is far superior & will lead to huge growth $4b MF alone. /126 https://t.co/n1m7D9YsgI https://x.com/kinatsofrim/status/1859619451772998019s=20 @VasNarasimhan" [X Link](https://x.com/kinatsofrim/status/2020295789650604357) 2026-02-08T00:37Z [---] followers, [---] engagements "@LavBaalDevarim @Shtarkasm @ModernTalmud No consensus on wether or not anan sahadi/umdena is a determinant (see Rema EH 42:1) but not the kind of matter that should be taken lightly" [X Link](https://x.com/kinatsofrim/status/2020603321837392130) 2026-02-08T20:59Z [---] followers, [--] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy $KPTI $INCY "Specifically Incyte will look for derisked pre-revenue or revenue-stage opportunities the new CEO said" /252 https://x.com/kinatsofrim/status/1950191113731772741 https://www.fiercepharma.com/pharma/incytes-new-ceo-pledges-fresh-look-business-outlines-dealmaking-strategy @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1" [X Link](https://x.com/kinatsofrim/status/1952404585877844296) 2025-08-04T16:21Z [---] followers, [----] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive $INCY is muddying MF & ET together while ignoring mCALR prevalence in both is under 30%. They tiptoe around competitors but never mention $KPTI Odd to see such high-profile hype for a P1 & even preclinical" [X Link](https://x.com/kinatsofrim/status/1996617005357785194) 2025-12-04T16:26Z [---] followers, [----] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen $KPTI CMO and CEO today at Piper Sandler Healthcare Conference /305 https://x.com/kinatsofrim/status/1859619451772998019s=20 @VasNarasimhan Now that $NVS pelabresib is" [X Link](https://x.com/kinatsofrim/status/1996645516579688507) 2025-12-04T18:19Z [---] followers, [---] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen $KPTI PI/KOL Dr. John Mascarenhas @TheIACH Paris October [----]. /306 https://x.com/kinatsofrim/status/1949627317031944452s=20 @RaajitRampal @clinadvances @doctorpemm" [X Link](https://x.com/kinatsofrim/status/1996960603852644364) 2025-12-05T15:11Z [---] followers, [---] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI Sr. mgmt and Leading MPN KOL & SENTRY Co-investigator Dr. Claire Harrison @harrisoncn1 will participate in a virtual fireside chat as part of Baird's Biotech" [X Link](https://x.com/kinatsofrim/status/1998006770577350831) 2025-12-08T12:28Z [---] followers, [----] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI What is the purpose of Weds. KOL chat Can SENTRY be terminated for overwhelming efficacy Approx. 85-90% of SENTRY pts are now = [--] wks & 100% are = [--] wks." [X Link](https://x.com/kinatsofrim/status/1998106928711365013) 2025-12-08T19:06Z [---] followers, [---] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI Dr. Claire Harrison @harrisoncn1 "I was always taught that you should give your best therapy first.I would be giving this combo therapy to the majority of my" [X Link](https://x.com/kinatsofrim/status/1998837805556928653) 2025-12-10T19:30Z [---] followers, [---] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI Dr. Claire Harrison @harrisoncn1 How will community physicians approach combination therapy selinexor+ruxolitinib vs. ruxolitinib "They were probably taught the" [X Link](https://x.com/kinatsofrim/status/1998838962618515629) 2025-12-10T19:35Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers $INCY JPM "In terms of BD we see is a multiplier to extend/strengthen core we're not looking to chase deals fill rev gap or buy unbounded downside risk we want high fit opp. that have pot. to create durable rev erngs & cash flow into the nxt decade" /322 https://x.com/kinatsofrim/status/1965529333986197577s=20 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93" [X Link](https://x.com/kinatsofrim/status/2010770276947001405) 2026-01-12T17:46Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers $KPTI $GSK & SOBI @RaajitRampal /323 https://x.com/kinatsofrim/status/1922374810081903098s=20 https://clinicaltrials.gov/study/NCT07362225term=NCT07362225&rank=1 @bose_prithviraj @TaniaJain11 @Medscape @EHA_Hematology $KPTI's surprise data in HB improvement in MF will hurt $GSK's momelotinib. Would a combo with momelotinib have even better HB results @bose_prithviraj @doctorpemm @RaajitRampal @AaronGerds @MDmasarova @LindsayReinMD @TaniaJain11 @DrJoeScandura /210 https://t.co/I9rzv50WD9" [X Link](https://x.com/kinatsofrim/status/2015495380784365724) 2026-01-25T18:41Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal $NVS will have to start new P3 for pelabresib Manifest-3 h/t @ByMadeleineA /324 https://x.com/kinatsofrim/status/1896633966226247801s=20 https://www.oncologypipeline.com/apexonco/novartis-perseveres-pelabresib Today at the TD Cowen healthcare conference analyst Marc Frahm asks $INCY's Pablo Cagnoni about their BET inhibitor for 2L and the markets dismissiveness. Pablo also mentioned that $NVS's pelabresib will need to do a completely new study. h/t $KPTI /181 https://t.co/xGBDLP9Acp" [X Link](https://x.com/kinatsofrim/status/2015810326365679758) 2026-01-26T15:33Z [---] followers, [----] engagements "$GMAB on losing streak ouch @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma $GMAB @Genmab has entered the $KPTI chat /295 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline" [X Link](https://x.com/kinatsofrim/status/2015957753164935455) 2026-01-27T01:19Z [---] followers, [---] engagements "$KPTI CEO and $GMAB EVP/CCO worked together at Ipsen and $KPTI CMO Reshma Rangwala is Genmab alumni. Synergies in MM and EC" [X Link](https://x.com/kinatsofrim/status/2015967936066802000) 2026-01-27T01:59Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $GSK's momelotinib sales in Q4 $158mm small growth. $KPTI /325 https://x.com/kinatsofrim/status/1983561499185483940s=20 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma $GSK's momelotinib sales slowing down () in Q3 $146m vs." [X Link](https://x.com/kinatsofrim/status/2019004331819946038) 2026-02-04T11:05Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $GSK CEO Luke Miels on Q4 call sound like they have something in mind. $KPTI /326 https://x.com/kinatsofrim/status/1816218892911665457s=20 Who will aquire $KPTI Since the MF & EC landscapes have rapidly evolved in the last few months I'm going to narrow the poll down to these four $INCY $MRK $GSK $AZN (GSK is unique in that it has synergies in all [--] indications MMMF & EC + RUBY PI @MirzaCPH is $KPTI Board member) https://x.com/kinatsofrim/status/1816218892911665457s=20" [X Link](https://x.com/kinatsofrim/status/2019046634584433039) 2026-02-04T13:53Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA "IQQWiG concluded that the additional benefit of $GSK's momelotinib in this indication is "not proven" citing the companys deviaiton from the G-BA-defined comparator therapies and the lack of suitable supporoting evidence" /327 https://x.com/kinatsofrim/status/1922374810081903098s=20 https://www.navlindaily.com/article/29378/iqwig-finds-no-proven-additional-benefit-for-gsk-s-omjjara-in-myelofibrosis @bose_prithviraj @TaniaJain11 @Medscape @EHA_Hematology $KPTI's" [X Link](https://x.com/kinatsofrim/status/2019054069248069886) 2026-02-04T14:22Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA Cantor Fitzgerald initiates $KPTI with Overweight rating. Cantor "assigns approx 70% probability of success for SENTRY p3 and believes a successful trial outcome would reposition $KPTI from a challenged MM player to a frontline MF combo contender" /329 https://www.investing.com/news/analyst-ratings/cantor-fitzgerald-initiates-karyopharm-stock-with-overweight-rating-93CH-4486527" [X Link](https://x.com/kinatsofrim/status/2019376070462672902) 2026-02-05T11:42Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA If accurate that $GSK's momelotinib has low to minimal cytokine effects then $KPTI's selinexor would complement momelotinib well and can be initiated in patients with platelet counts below [-----]. /330 https://x.com/kinatsofrim/status/1922374810081903098s=20 @bose_prithviraj @TaniaJain11 @Medscape @EHA_Hematology $KPTI's surprise data in HB improvement in MF will hurt $GSK's momelotinib. Would a combo with momelotinib have even better HB results @bose_prithviraj" [X Link](https://x.com/kinatsofrim/status/2019807114420789326) 2026-02-06T16:15Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $KPTI Throw in the phase [--] Xport-EC-042 (topline mid Q2) that's another $1b in sales. /333 https://x.com/kinatsofrim/status/1948428547976024540s=20 $KPTI Thank you Dr. Krivak @AHNtoday "I think SEINDO was I don't want say a sleeper trial. how did this slip by the radar. profound results. absolutely remarkable. tremendously exciting" h/t Dr. Gottfried Konecny @UCLAHealth Dr. Leslie Randall @VCUHealth and @OncLive https://t.co/lbqvKUllGp" [X Link](https://x.com/kinatsofrim/status/2020297929064423755) 2026-02-08T00:45Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $GSK's momelotinib: SIMPLIFY-1 JAKi-nave vs Rux showed similar NI TSS to rux. It *did not meet the NI criterion for superior TSS50 comp. to rux* it provided superior TI & reduced TB. SIMPLIFY-2 Post Rux vs BAT showed superior TSS & TI comp. to BAT. /334 https://x.com/kinatsofrim/status/1852391156027412786s=20 On yesterday's $KPTI KOL call PI Dr. John Mascarenhas talked about ruxolitinib and selinexor having no overlapping toxicities while other jak inhibitors $GSK" [X Link](https://x.com/kinatsofrim/status/2020333941576855569) 2026-02-08T03:08Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA The FDA oddly gave $GSK's momelotinib approval for 1L when application was for 2L. Fast forward now the German's at IQWiG are challenging them (see earlier in thread #327) coupled with slowish sales (ibid #325). /335 https://x.com/kinatsofrim/status/1816218892911665457s=20 Who will aquire $KPTI Since the MF & EC landscapes have rapidly evolved in the last few months I'm going to narrow the poll down to these four $INCY $MRK $GSK $AZN (GSK is unique in that it has" [X Link](https://x.com/kinatsofrim/status/2020341177476845943) 2026-02-08T03:37Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA With $KPTI SENTRY P3 topline early March CEO booked gig @LongwoodLeaders for March [--] /336 https://www.longwoodhealthcareleaders.com/miamiceo https://www.longwoodhealthcareleaders.com/miamiceo" [X Link](https://x.com/kinatsofrim/status/2020463035056308349) 2026-02-08T11:41Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders Early SVR improvement results in bigger drop in Abs-TSS further SVR improvement produces less Abs-TSS True SVR/TSS relationship is curved pushing $KPTI SENTRY PoS from 70% to 80% bs"d. /337" [X Link](https://x.com/kinatsofrim/status/2020924718904377595) 2026-02-09T18:16Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders $INCY CEO BD comment on Q4 call this morning. Bottom line: ruxolitinib makes up two-thirds of thier total revenue. They'll have to deal with several years of serious drop in revenue even IF by some miracle everything in their pipeline got approved. /338 https://x.com/kinatsofrim/status/1985400941315522864s=20 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat" [X Link](https://x.com/kinatsofrim/status/2021235881353380010) 2026-02-10T14:52Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers If $KPTI's SENTRY reads out positive $INCY's MF franchise will be in trouble. and if SENTRY-2 is positive it over for them. /321 https://x.com/kinatsofrim/status/1985400941315522864s=20 https://x.com/kinatsofrim/status/1985400941315522864s=20" [X Link](https://x.com/anyuser/status/2010693715044577408) 2026-01-12T12:41Z [---] followers, [----] engagements "New - New - @DBashIdeas https://t.co/LYjyEWrFB0 New - @DBashIdeas https://t.co/LYjyEWrFB0" [X Link](https://x.com/kinatsofrim/status/2019133443641339922) 2026-02-04T19:38Z [---] followers, [----] engagements "Last week Ron Gvili hyd was recovered so went for something new (Zuriman) for kiddush. Medium body earthy slight traces of hibiscus grated on apple bark lightly sweetened gribenes and faint notes of fig #KSbottles @minhagim Maybe online too though got this locally. Havent been able to fully relish and get in the zone π€·β @minhagim Maybe online too though got this locally. Havent been able to fully relish and get in the zone π€·β" [X Link](https://x.com/kinatsofrim/status/2019877079299551395) 2026-02-06T20:53Z [---] followers, [---] engagements "RT @kinatsofrim: @Yahrtzeits [--] Shvat: Rav Yechezkel Mazuz of Djerba - Netivot (1926-2022)" [X Link](https://x.com/anyuser/status/2020603839641227770) 2026-02-08T21:01Z [---] followers, [--] engagements "Tell me your political views without telling me your political views (Robert Alter)" [X Link](https://x.com/kinatsofrim/status/2021055744678953466) 2026-02-10T02:56Z [---] followers, [---] engagements "New '' - " New - https://t.co/2g7yoGamz0 New - https://t.co/2g7yoGamz0" [X Link](https://x.com/kinatsofrim/status/2021280450124100043) 2026-02-10T17:49Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders $KPTI Millennium picks up 5.5% of the company. /340" [X Link](https://x.com/kinatsofrim/status/2021595669832614399) 2026-02-11T14:42Z [---] followers, [---] engagements "I feel this" [X Link](https://x.com/kinatsofrim/status/2021676475225629119) 2026-02-11T20:03Z [---] followers, [---] engagements "@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders $KPTI on Q4 call CMO goes after $INCY /341 https://x.com/kinatsofrim/status/2010693715044577408s=20 @harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers If $KPTI's SENTRY reads out positive $INCY's MF franchise will be in trouble. and if SENTRY-2 is positive it over for them. /321 https://t.co/yIYwUmPBk2 https://t.co/I6Fd8vw94K https://x.com/kinatsofrim/status/2010693715044577408s=20 @harrisoncn1 @peter_mpn" [X Link](https://x.com/kinatsofrim/status/2021957118178541842) 2026-02-12T14:38Z [---] followers, [---] engagements "New ' ' - New - @HQSatmar https://t.co/mv99hqPTAK New - @HQSatmar https://t.co/mv99hqPTAK" [X Link](https://x.com/kinatsofrim/status/2022389002503086121) 2026-02-13T19:14Z [---] followers, [--] engagements "@sahsan10 @alexforschner $KPTI Back in" [X Link](https://x.com/kinatsofrim/status/2022420317168374043) 2026-02-13T21:19Z [---] followers, [--] engagements "Hakham Zvi never used stunt doubles" [X Link](https://x.com/kinatsofrim/status/1827904206751047765) 2024-08-26T03:01Z [---] followers, [---] engagements "27 Av @Yahrtzeits: Reb Shmuel Tzvi Horowitz of Spinka aka Reb Hersheller (1921-1997). He was instrumental in his nephew R' Naftali Horowitz's life trajectory @EliLanger" [X Link](https://x.com/kinatsofrim/status/1830353822230651126) 2024-09-01T21:15Z [---] followers, [----] engagements "@endimem_music I wonder if Trump can make it through Bobby Lee's childhood story without flinching" [X Link](https://x.com/kinatsofrim/status/1831134549692039636) 2024-09-04T00:57Z [---] followers, [---] engagements "R' Michoel Sorotzkin makes a fascinating observation on the connection between Rav Avremel Ausband Ztl and the Meshech Chochma Rav Meir Simcha Ztl part [--] Rav Mordechai Willig bids a tearful goodbye to Rav Avremel Ausband his dear friend and neighbor of [--] years. https://t.co/UB5mZuftIy Rav Mordechai Willig bids a tearful goodbye to Rav Avremel Ausband his dear friend and neighbor of [--] years. https://t.co/UB5mZuftIy" [X Link](https://x.com/kinatsofrim/status/1832848732200575089) 2024-09-08T18:29Z [---] followers, [----] engagements "20 Elul @Yahrtzeits: Mekubal Rav Avraham Monsa (1912-2008)" [X Link](https://x.com/kinatsofrim/status/1838298359833989198) 2024-09-23T19:24Z [---] followers, [---] engagements "My favorite part of @DBashIdeas interview with Reb Tuvia @tenenbom" [X Link](https://x.com/kinatsofrim/status/1838974908300136664) 2024-09-25T16:12Z [---] followers, [----] engagements "More likely: [--] Elul @Yahrtzeits: R Yaakov Tam b. Meir. Rabenu Tam passed away on the eve of RH. I have on tradition when Rashi died RT heard a heavenly echo crying. I think the Luster of Israel was extinguished said RTs mother. And RT replied I will rekindle it. [--] Tamuz: R'Yaakov Ben Meir Tam of Romereau Rabbeinu Tam (1100-1171). One of the primary authors of the Tosafos commentary on the Gemara. Grandson of Rashi. He was called Tam due to his wholesomeness and righteousness. Some of his responsa are collected in Sefer Hayashar. https://t.co/UOpJ0BzZAx [--] Tamuz: R'Yaakov Ben Meir Tam of" [X Link](https://x.com/kinatsofrim/status/1841275965609005286) 2024-10-02T00:36Z [---] followers, [----] engagements "New from R' Yaakov Sasson (trigger warning @endimem_music R' Dovid @DBashIdeas gets a nice shout-out)" [X Link](https://x.com/kinatsofrim/status/1853862732199850103) 2024-11-05T18:11Z [---] followers, [----] engagements "@TheLastRefuge2 This should be read not once not twice but [---] times. We have a teaching reviewing ones studies [---] times ensures it won't be forgotten :) @DonaldJTrumpJr @EricTrump @elonmusk" [X Link](https://x.com/kinatsofrim/status/1856102276622102561) 2024-11-11T22:30Z [---] followers, [---] engagements "@allisonoconor reminds me of @stoolpresidente at the State Fair of Texas" [X Link](https://x.com/kinatsofrim/status/1857125860131917969) 2024-11-14T18:18Z [---] followers, [--] engagements "@krotchetygaon @endimem_music TR baller rolls up with trophy Mekubal at his side" [X Link](https://x.com/kinatsofrim/status/1859272024499122245) 2024-11-20T16:26Z [---] followers, [--] engagements "In Telz if you wanted to borrow Uncle Toms Cabin - R Lazer Gordons home was the right address" [X Link](https://x.com/kinatsofrim/status/1866309378267079086) 2024-12-10T02:30Z [---] followers, [----] engagements "@FrumTikTok According to the mothers narrative thats quite a misunderstanding about the style of haircut unless the barber was deaf and blind π€·β" [X Link](https://x.com/kinatsofrim/status/1867404028973351418) 2024-12-13T02:59Z [---] followers, [----] engagements "Nothing to see here; was a simple mistake. No deep secrets. β€" [X Link](https://x.com/kinatsofrim/status/1872345437619065219) 2024-12-26T18:15Z [---] followers, [----] engagements "Tonight 6th night of Chanuka is the @Yahrtzeits of Reb Pinchas Kehati (1910-1976). Author of the monumental "Mishnayos Mevoaros" (aka Kehati Mishnayos) @Yahrtzeits R Pinchos Kehati (though in the 6th candle was lit on [--] Teves): https://t.co/ycoxx8n1tl @Yahrtzeits R Pinchos Kehati (though in the 6th candle was lit on [--] Teves): https://t.co/ycoxx8n1tl" [X Link](https://x.com/kinatsofrim/status/1873873462059819255) 2024-12-30T23:27Z [---] followers, [----] engagements "New π: After many years working on Rashis torah comm. and the early supercommentaries. R Moshe Philip now released a volume analyzing all the places Ramban deals with Rashi @ek2220 @rashi_in @ChananyaBerman @DBashIdeas Thank you @ek2220 for bringing this to my attention ππ» https://t.co/qw5Bjf89BI @ek2220 @rashi_in @ChananyaBerman @DBashIdeas Thank you @ek2220 for bringing this to my attention ππ» https://t.co/qw5Bjf89BI" [X Link](https://x.com/kinatsofrim/status/1874181007458635898) 2024-12-31T19:49Z [---] followers, [---] engagements "@endimem_music For some reason that one rebbe who shines when it comes to these Rashis isn't respected by the other Rebbiem who skip them" [X Link](https://x.com/kinatsofrim/status/1875020937357328785) 2025-01-03T03:26Z [---] followers, [----] engagements "@TheLastRefuge2 Heads up Gowdy on the radio now with Judge Jeanine (paraphrasing) "I just went on a trip with my very good friend the incoming CIA director John Ratcliffe."" [X Link](https://x.com/kinatsofrim/status/1875950006542463001) 2025-01-05T16:58Z [---] followers, [----] engagements "@DBashIdeas" [X Link](https://x.com/kinatsofrim/status/1876078768621834600) 2025-01-06T01:30Z [---] followers, [---] engagements "@endimem_music Enough is enough we need a hashgacha entity to approve podcasts. Will call it " [X Link](https://x.com/kinatsofrim/status/1876121000620052494) 2025-01-06T04:17Z [---] followers, [---] engagements "@endimem_music Manic Menahse threw all his sister's american girl dolls into the chametz fire" [X Link](https://x.com/kinatsofrim/status/1876132673678389675) 2025-01-06T05:04Z [---] followers, [----] engagements "6 Teves @Yahrtzeits: R Sasson (b. Mordechai) Shinduch (1747-1830) sometimes nicknamed Adjmi. Rav in highly regarded mekubal and darshan payytan artisan and authored many seforim; later some were lost in a fire in 1860" [X Link](https://x.com/kinatsofrim/status/1876465698563887553) 2025-01-07T03:07Z [---] followers, [---] engagements "The story of the geirei tzedek Reb Moshe Hattori and his wife Tzipora of Shaare Chesed is truly amazing. non-stop mesiras nefesh both former Japanese pastors. to becoming a full fledged Gra'nik and a close student of Rav Shmuel Aurbach ztl @jacklanger do your thing" [X Link](https://x.com/kinatsofrim/status/1876829786925826469) 2025-01-08T03:14Z [---] followers, [----] engagements "R Yaacov de Illescas in his Imrei Noam quoted a Yerushalmi containing a suspicious ending. L Ginzberg said he only found this word-play in a note on Yad Ramah. S Lieberman in his personal copy of Gs comm. added in the margin Read: After Lieberman showed meπ" [X Link](https://x.com/kinatsofrim/status/1878624425739968620) 2025-01-13T02:05Z [---] followers, [----] engagements "mesivta struggles #438 Phzurrrrrxiptzkna Belaaz Oh okay. I get it now mesivta struggles #438 Phzurrrrrxiptzkna Belaaz Oh okay. I get it now" [X Link](https://x.com/kinatsofrim/status/1878970693020455398) 2025-01-14T01:01Z [---] followers, [----] engagements "@endimem_music @IraZlotowitz @GPARENCY Too many bachurim in the mid/upper twenties delaying entering the work force and instead pretending to learn three sedorim bec the fear of being stigmatized & shidduch prospects" [X Link](https://x.com/kinatsofrim/status/1889829904889573718) 2025-02-13T00:12Z [---] followers, [----] engagements "Unidentified avrech studying halachos of kosher birds and this happens This only happens to you once. π https://t.co/7c8WlKRrWm This only happens to you once. π https://t.co/7c8WlKRrWm" [X Link](https://x.com/kinatsofrim/status/1890159799989596300) 2025-02-13T22:03Z [---] followers, [----] engagements "The fact that RHS misremembered the details quoting from the original ToC -which doesnt appear in the newer ed.- only tells me he how great of a he is prob relying on his and that he would learn the maftechos too. (Attn seforim publishers: Keep the original)" [X Link](https://x.com/kinatsofrim/status/1894837400154550448) 2025-02-26T19:50Z [---] followers, [---] engagements "@TheLastRefuge2 "Pam Bondi is the Sean Hannity of U.S. Attorney Generals" - pure gold" [X Link](https://x.com/kinatsofrim/status/1895315979531624698) 2025-02-28T03:31Z [---] followers, [---] engagements "$KPTI $BMY $ONC (Beigene) https://x.com/kinatsofrim/status/1758575825689952644 $BMY picks up both $KPTI & @antengene one-two punch https://t.co/RShZm2KauC https://t.co/z83VaQhrs6 https://x.com/kinatsofrim/status/1758575825689952644 $BMY picks up both $KPTI & @antengene one-two punch https://t.co/RShZm2KauC https://t.co/z83VaQhrs6" [X Link](https://x.com/kinatsofrim/status/1909763127664607265) 2025-04-09T00:19Z [---] followers, [---] engagements "R Shmuel Palagi was compelled to print a resp. re. a halachic controversy that stirred in his community of Hamburg. Toward the end of this short vol. he raised other unrelated concerns [--] of them being his condemnation of the popular European poem sung @ end of Haggadah" [X Link](https://x.com/kinatsofrim/status/1913032741978886586) 2025-04-18T00:52Z [---] followers, [----] engagements "That time when the distinguished kabbalist Rashash wanted to be stringent following a Lurianic custom but acquiesced to -it seems- his wifes urging him to shave" [X Link](https://x.com/kinatsofrim/status/1924875340725326243) 2025-05-20T17:10Z [---] followers, [----] engagements "That time when Prof. Saul Lieberman was introduced to Yemenite jewry through the very learned but unassuming shamis/shamosh (custodian)" [X Link](https://x.com/kinatsofrim/status/1935393152577233031) 2025-06-18T17:44Z [---] followers, [----] engagements "@endimem_music Anachnu ma'aminim Fishy Swishy" [X Link](https://x.com/kinatsofrim/status/1938044683420373138) 2025-06-26T01:20Z [---] followers, [----] engagements "Casually obviates some dozen+ seforim on kelalei SA. No googling or OtzarH; leave your thoughts below" [X Link](https://x.com/kinatsofrim/status/1950197325252506059) 2025-07-29T14:10Z [---] followers, [----] engagements "$ONC (Beigene) @johnvoyler Jul [--] sold [-----] shares for a total value of $7.04mm. @BeOneMedicines @johnvoyler it's time. https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to the possibilities to make sure that we maximize the potential of Selinexor + Rux $INCY". /1 https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive" [X Link](https://x.com/kinatsofrim/status/1950352242004914600) 2025-07-30T00:26Z [---] followers, [---] engagements "From R Chaim Vitals son R Shmuel Casually obviates some dozen+ seforim on kelalei SA. No googling or OtzarH; leave your thoughts below. https://t.co/af8JEs7rUW Casually obviates some dozen+ seforim on kelalei SA. No googling or OtzarH; leave your thoughts below. https://t.co/af8JEs7rUW" [X Link](https://x.com/kinatsofrim/status/1950564955562123474) 2025-07-30T14:31Z [---] followers, [----] engagements "@GilStudent Conversely why are some pesukim in Megilas Esther read on Purim with an Eicha tune So Litvaks too would have some simchas Purim. Then why dont we read the whole Megila like that Bec that would already be holelus" [X Link](https://x.com/kinatsofrim/status/1952214710721581105) 2025-08-04T03:47Z [---] followers, [---] engagements "Reb Zelig in Beis Din @endimem_music" [X Link](https://x.com/kinatsofrim/status/1952422328450638043) 2025-08-04T17:32Z [---] followers, [----] engagements "@FieldSpeakerZDQ Oh absolutely its wild. Prob once a week i come across a new guy. Insanity. Have a whole theory about the phenomenon the why & the how and then the spiraling broader affects etc. but watevs not for here. Basically its mostly charlatanism with some kabbalah cosplay" [X Link](https://x.com/kinatsofrim/status/1956418000904442136) 2025-08-15T18:09Z [---] followers, [---] engagements "$RPRX Royalty Pharma to pay up to $950 million for royalties from $AMGN lung cancer drug. $KPTI CEO is also $AMGN alumni down-payment + two cvr's https://www.reuters.com/legal/litigation/royalty-pharma-pay-up-950-million-royalties-amgens-lung-cancer-drug-2025-08-25/ cont. Although a total BO from $AMGN isn't impossible. They bought Onyx/Kyprolis where $KPTI previous CEO MK was cmo. In reality it looks like $KPTI is betting it all on Endo and MF. MM is just better than nothing." [X Link](https://x.com/kinatsofrim/status/1960442556790997328) 2025-08-26T20:41Z [---] followers, [----] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive $INCY CEO @ Evercore "BD like in any situation is going to be supplemental. It can be a multiplier of our growth. We'll do things that extend or strengthen the core & be really smart about how we use the" [X Link](https://x.com/kinatsofrim/status/1996291613329613127) 2025-12-03T18:53Z [---] followers, [---] engagements "@harrisoncn1 $KPTI Thank you Dr. Claire Harrison @harrisoncn1 /314 https://x.com/kinatsofrim/status/1752708130104865005s=20 $KPTI @AlbertBourla @MyOncology @BarryGreene Yeshiva week is over let's go. https://t.co/q0loycv6e8 https://x.com/kinatsofrim/status/1752708130104865005s=20 $KPTI @AlbertBourla @MyOncology @BarryGreene Yeshiva week is over let's go. https://t.co/q0loycv6e8" [X Link](https://x.com/kinatsofrim/status/1998947907245060329) 2025-12-11T02:48Z [---] followers, [---] engagements "@harrisoncn1 $KPTI Add'l important cmts. from @harrisoncn1 no ITP increase symptom response with seli mono striking we can be reasonably reassured excited for topline robust study design early sfty data reassuring no need to dose adjust dosing is straightforward /315" [X Link](https://x.com/kinatsofrim/status/1999129118244274503) 2025-12-11T14:48Z [---] followers, [---] engagements "@AaronRosenblum5 @DueDoctor Other possibilities. $INCY buying back rux rights from $NVS as @IloveIncyte wants to expand to the EU and this way they also settle lawsuit see link. Or $INCY buying selinexor rights from @Stemline to close on $KPTI https://casetext.com/case/novartis-pharma-ag-v-incyte-corp-12 https://casetext.com/case/novartis-pharma-ag-v-incyte-corp-12" [X Link](https://x.com/kinatsofrim/status/1857461506230648995) 2024-11-15T16:31Z [---] followers, [----] engagements "@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy $KPTI CFO dialed up Centerview as she worked with them last year while at $LEGN Question: Why is CVP getting involved with $KPTI situation Acquisition $INCY $NVS $MRK $GSK $BMY $ABBV $RHHBY $SNY $AZN SOBI Dilution C11 /253 https://x.com/kinatsofrim/status/1947821628676837439 https://www.fiercepharma.com/pharma/legend-biotech-ceo-takes-close-look-business-amid-geopolitical-risk-ma-rumor" [X Link](https://x.com/kinatsofrim/status/1953104616553329106) 2025-08-06T14:43Z [---] followers, [----] engagements "$KPTI Thank you @MirzaCPH for all your valuable contributions over the years. $KPTI Board member and RUBY $GSK PI/KOL Dr. @MirzaCPH was @myESMO Italy June [----] "Predicting the Future" https://t.co/P84yJJqs3V $KPTI Board member and RUBY $GSK PI/KOL Dr. @MirzaCPH was @myESMO Italy June [----] "Predicting the Future" https://t.co/P84yJJqs3V" [X Link](https://x.com/kinatsofrim/status/1966250565643678147) 2025-09-11T21:20Z [---] followers, [---] engagements "In April @MirzaCPH became CMO at Acrivon Therapeutics. He didn't resign from $KPTI then. Why now Potential conflict with acquiring party https://x.com/kinatsofrim/status/1948428547976024540 https://ir.acrivon.com/news-releases/news-release-details/acrivon-therapeutics-appoints-world-renowned-oncology-key $KPTI Thank you Dr. Krivak @AHNtoday "I think SEINDO was I don't want say a sleeper trial. how did this slip by the radar. profound results. absolutely remarkable. tremendously exciting" h/t Dr. Gottfried Konecny @UCLAHealth Dr. Leslie Randall @VCUHealth and @OncLive https://t.co/lbqvKUllGp" [X Link](https://x.com/kinatsofrim/status/1966313845430898880) 2025-09-12T01:32Z [---] followers, [---] engagements "New " from Rav Yechezkel Mazuz ztl son of Rav Shlomo ztl https://www.bhol.co.il/news/1330434 @abekay2 @Yahrtzeits https://t.co/RsAQZdOOwr https://www.bhol.co.il/news/1330434 @abekay2 @Yahrtzeits https://t.co/RsAQZdOOwr" [X Link](https://x.com/kinatsofrim/status/1620423479173734402) 2023-01-31T14:07Z [---] followers, [----] engagements "@Yahrtzeits [--] Shvat: Rav Yechezkel Mazuz of Djerba - Netivot (1926-2022) New " from Rav Yechezkel Mazuz ztl son of Rav Shlomo ztl https://t.co/ra1FniIkeT https://t.co/bJTe8tjgbW New " from Rav Yechezkel Mazuz ztl son of Rav Shlomo ztl https://t.co/ra1FniIkeT https://t.co/bJTe8tjgbW" [X Link](https://x.com/kinatsofrim/status/1625161960189792256) 2023-02-13T15:56Z [---] followers, [----] engagements "https://youtu.be/RKgcb-QjYQ4 https://youtu.be/RKgcb-QjYQ4" [X Link](https://x.com/kinatsofrim/status/1627389455727206401) 2023-02-19T19:27Z [---] followers, [---] engagements "@minhagim Maybe online too though got this locally. Havent been able to fully relish and get in the zone π€·β" [X Link](https://x.com/kinatsofrim/status/1743336925514383793) 2024-01-05T18:21Z [---] followers, [---] engagements "$KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to the possibilities to make sure that we maximize the potential of Selinexor + Rux $INCY". /1 From Cantor: biotech M&A transactions took an avg of [----] mos in [----]. From start of deals talks to deal announcement. Assume deal talks start after data confirming this and how long after data. https://t.co/FrVTkJiekN From Cantor: biotech M&A transactions took an avg of [----] mos in [----]. From start of deals talks to deal" [X Link](https://x.com/anyuser/status/1768375601847501223) 2024-03-14T20:36Z [---] followers, 40.5K engagements "New - @HQSatmar" [X Link](https://x.com/kinatsofrim/status/1906434766477336774) 2025-03-30T19:54Z [---] followers, [----] engagements "$KPTI Warm welcome to @alexforschner https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to the possibilities to make sure that we maximize the potential of Selinexor + Rux $INCY". /1 https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to" [X Link](https://x.com/kinatsofrim/status/1923173919286005983) 2025-05-16T00:29Z [---] followers, [---] engagements "@sahsan10 @alexforschner Did you guys buyout the $25m note due in Oct. at a discount" [X Link](https://x.com/kinatsofrim/status/1923500691181461589) 2025-05-16T22:07Z [---] followers, [---] engagements Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing
@kinatsofrim @KinatSofrim@KinatSofrim posts on X about $kpti, $incy, $nvs, ceo the most. They currently have [---] followers and [---] posts still getting attention that total [-----] engagements in the last [--] hours.
Social category influence stocks 21.24% finance 4.42% countries 3.54% currencies 1.77% cryptocurrencies 1.77% automotive brands 0.88% travel destinations 0.88% musicians 0.88% celebrities 0.88%
Social topic influence $kpti #2, $incy #4, $nvs #10, ceo 7.96%, $gsk #7, in the 6.19%, $gsks #1, $kptis #1, pi 3.54%, $incys #1
Top accounts mentioned or mentioned by @harrisoncn1 @raajitrampal @bloodcancers @boseprithviraj @petermpn @kartosthera @buysidebio @biopharmaddict @doctorpemm @taniajain11 @medscape @vasnarasimhan @bymadeleinea @antengene @mdmasarova @clinadvances @mkremyanskaya @doclucchesi @erictokat @icahnmountsinai
Top assets mentioned Incyte Corporation (INCY) Novartis AG (NVS) GSK plc (GSK) Merck & Co., Inc. (MRK) Geron Corp (GERN) AbbVie Inc (ABBV) Bristol-Myers Squibb Co (BMY) AstraZeneca PLC (AZN) One Cash (ONC) Frontline Ltd. (FRO) Amgen, Inc. (AMGN) Royalty Pharma plc (RPRX) Legend Biotech Corp (LEGN)
Top posts by engagements in the last [--] hours
"@BaldwynKing @EladStr @JasonMBrodsky @biannagolodryga Theyre very influential people. they control media - If you think by theyre/they he meant Israel then I agree youre not just playing dumb"
X Link 2021-05-20T20:41Z [---] followers, [--] engagements
"PSA for those beginning mas. Taanit tomorrow: Dont get overly pedantic with Rashi (especially not s) more than you would with any other Rishon; cf. referenced literature in the note below:"
X Link 2021-11-14T02:26Z [---] followers, [--] engagements
"A very welcome reprint. As all of R Yaacov Haim Sofers books are packed with content of all sorts (he has great tangents π€) this set has now been reprinted with a very valuable index (for all 12vols) and some other minor corrections"
X Link 2022-08-05T01:41Z [---] followers, [--] engagements
"I guess the anonymous author included this for posterity:"
X Link 2022-08-23T00:52Z [---] followers, [--] engagements
"@ayilbasvach She clearly follows the Rama to make the Bracha after we light and not like the Mechaber to make the Bracha before "
X Link 2022-08-24T02:18Z [---] followers, [--] engagements
"PSA to all Yoel's out there. When you go into the workforce you don't need to automatically become a Joel Yoel Roth @yoyoel"
X Link 2022-11-02T13:23Z [---] followers, [--] engagements
"@Yahrtzeits [--] Cheshvon: R' Moshe (b. Yosef) Levi (1961-2000). Greatly influnetial posek & dedicated Rosh Mesivta in Kisse Rahamim. Authored famous seforim on Shabbat (Menuhat Ahavah) usery (Malveh Hashem) blessings (Birkat Hashem) responsa and more"
X Link 2022-11-04T15:46Z [---] followers, [--] engagements
"@endimem_music Lashon hara CC Heritage Foundation β Talking in shul Stopthetalking. org β Tznius Vaad Mishmeres Haznius β Internet TAG β Tithe giving @kupat_hair β Shmiras einayim Young Balabatim Players β Do things le'shem shamayim Untapped market"
X Link 2022-11-25T01:13Z [---] followers, [--] engagements
"In time for his @Yahrtzeits [--] Shvat: (1928-2021) New ' on the life of the Tzaddik R' Binyamin Cohen of Moshav Berechya. Rav Shach in the 70's said he's a . Rav Schwadron after spending shabbasim in his house in Berechhya said he was one of the " tzaddikim"
X Link 2023-02-09T19:57Z [---] followers, [----] engagements
"7 Nissan @Yahrtzeits Mekubal Rav Sasson Mizrahi (1913-1998) author of Basi LeGani on the Etz Hayyim"
X Link 2023-03-29T02:18Z [---] followers, [----] engagements
"8 Teves @Yahrtzeits: Rav Yitzchak Assabag (1888-1971) Dayan and Rosh Yeshiva in Meknes Morocco"
X Link 2023-12-20T02:20Z [---] followers, [----] engagements
"11 Teves @Yahrtzeits: Mekubal R' Yehoshua Sharabani of Baghdad Iraq;later on a Rav of Baka Jerusalem; premier student of the Ben Ish Chai (1872-1972)"
X Link 2023-12-22T18:09Z [---] followers, [----] engagements
"$KPTI $INCY $NVS $GSK h/t @pec_panco_Alex /48 https://x.com/kinatsofrim/status/1754123089904861511 @777archie @doepke_michel Pelabresib ($MOR) failed TSS50 in P3. Navitoclax ($ABBV) failed TSS50 in P3. Navtemadlin (Kartos) both SVR & TSS50 SS were in the 30's. Imetelstat ($GERN) SA; SVR 10+% and TSS50 low 30's. It's not hard to see $KPTI competitiveness at this point. @IloveIncyte @AlbertBourla https://x.com/kinatsofrim/status/1754123089904861511 @777archie @doepke_michel Pelabresib ($MOR) failed TSS50 in P3. Navitoclax ($ABBV) failed TSS50 in P3. Navtemadlin (Kartos) both SVR & TSS50 SS were"
X Link 2024-08-15T20:13Z [---] followers, [---] engagements
"FDA to PharmaEssentia "symptom score (TSS50) will be a required co-primary endpoint" $NVS $INCY $KPTI $GSK $ABBV @adamfeuerstein /49"
X Link 2024-08-16T03:07Z [---] followers, [---] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive $KPTI Thank you @bose_prithviraj h/t @Blood_Cancers $NVS's pelabresib failed both absolute TSS reduction and TSS50 $INCY it's time to act. /303 https://x.com/kinatsofrim/status/1852014483847209241s=20"
X Link 2025-12-04T01:54Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict $KPTI Thank you Dr. @bose_prithviraj Dr. Nikolai Podoltsev @YaleCancer h/t @Blood_Cancers SENTRY & SENTRY-2 /320 https://www.bloodcancerstoday.com/post/six-things-the-2025-sentry-study-data-tell-us-about-the-future-of-myelofibrosis https://www.bloodcancerstoday.com/post/six-things-the-2025-sentry-study-data-tell-us-about-the-future-of-myelofibrosis"
X Link 2025-12-31T19:34Z [---] followers, [---] engagements
"@komatinskys @harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal Notably missing $GERN $BMY Kartos & PharmaEssentia"
X Link 2026-01-25T21:50Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $NVS confirm they'll need start new phase [--] for bet inhibitor pelabresib. $KPTI /328 https://x.com/kinatsofrim/status/2015810326365679758s=20 @harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal $NVS will have to start new P3 for pelabresib Manifest-3 h/t @ByMadeleineA https://t.co/GHRHybWNYI /324 https://t.co/3cMZfstdkF https://x.com/kinatsofrim/status/2015810326365679758s=20 @harrisoncn1 @peter_mpn @KartosThera"
X Link 2026-02-04T17:31Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $KPTI /331 https://x.com/kinatsofrim/status/1977773684640350246s=20 @komatinskys @jfais20 $KPTI Investigators were compelled & wowed by the [---] data (heavily pre treated population) especially the IL-8 disease modification cytokines. https://t.co/iWxsTUpGLk https://x.com/kinatsofrim/status/1977773684640350246s=20 @komatinskys @jfais20 $KPTI Investigators were compelled & wowed by the [---] data (heavily pre treated population) especially the IL-8 disease modification"
X Link 2026-02-06T16:17Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $KPTI just in MF alone. /332 https://x.com/kinatsofrim/status/1859619451772998019s=20 @VasNarasimhan Now that $NVS pelabresib is officially dead $KPTI forecast of $1b sales is extremely low given the fact $INCY Rux sales $2.2b for half the efficacy 30% drop off opposed to the efficacy durability data of Seli which is far superior & will lead to huge growth $4b MF alone. /126 https://t.co/n1m7D9YsgI https://x.com/kinatsofrim/status/1859619451772998019s=20 @VasNarasimhan"
X Link 2026-02-08T00:37Z [---] followers, [---] engagements
"@LavBaalDevarim @Shtarkasm @ModernTalmud No consensus on wether or not anan sahadi/umdena is a determinant (see Rema EH 42:1) but not the kind of matter that should be taken lightly"
X Link 2026-02-08T20:59Z [---] followers, [--] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy $KPTI $INCY "Specifically Incyte will look for derisked pre-revenue or revenue-stage opportunities the new CEO said" /252 https://x.com/kinatsofrim/status/1950191113731772741 https://www.fiercepharma.com/pharma/incytes-new-ceo-pledges-fresh-look-business-outlines-dealmaking-strategy @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1"
X Link 2025-08-04T16:21Z [---] followers, [----] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive $INCY is muddying MF & ET together while ignoring mCALR prevalence in both is under 30%. They tiptoe around competitors but never mention $KPTI Odd to see such high-profile hype for a P1 & even preclinical"
X Link 2025-12-04T16:26Z [---] followers, [----] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen $KPTI CMO and CEO today at Piper Sandler Healthcare Conference /305 https://x.com/kinatsofrim/status/1859619451772998019s=20 @VasNarasimhan Now that $NVS pelabresib is"
X Link 2025-12-04T18:19Z [---] followers, [---] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen $KPTI PI/KOL Dr. John Mascarenhas @TheIACH Paris October [----]. /306 https://x.com/kinatsofrim/status/1949627317031944452s=20 @RaajitRampal @clinadvances @doctorpemm"
X Link 2025-12-05T15:11Z [---] followers, [---] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI Sr. mgmt and Leading MPN KOL & SENTRY Co-investigator Dr. Claire Harrison @harrisoncn1 will participate in a virtual fireside chat as part of Baird's Biotech"
X Link 2025-12-08T12:28Z [---] followers, [----] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI What is the purpose of Weds. KOL chat Can SENTRY be terminated for overwhelming efficacy Approx. 85-90% of SENTRY pts are now = [--] wks & 100% are = [--] wks."
X Link 2025-12-08T19:06Z [---] followers, [---] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI Dr. Claire Harrison @harrisoncn1 "I was always taught that you should give your best therapy first.I would be giving this combo therapy to the majority of my"
X Link 2025-12-10T19:30Z [---] followers, [---] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive @adamfeuerstein @EvidenceOpen @TheIACH $KPTI Dr. Claire Harrison @harrisoncn1 How will community physicians approach combination therapy selinexor+ruxolitinib vs. ruxolitinib "They were probably taught the"
X Link 2025-12-10T19:35Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers $INCY JPM "In terms of BD we see is a multiplier to extend/strengthen core we're not looking to chase deals fill rev gap or buy unbounded downside risk we want high fit opp. that have pot. to create durable rev erngs & cash flow into the nxt decade" /322 https://x.com/kinatsofrim/status/1965529333986197577s=20 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93"
X Link 2026-01-12T17:46Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers $KPTI $GSK & SOBI @RaajitRampal /323 https://x.com/kinatsofrim/status/1922374810081903098s=20 https://clinicaltrials.gov/study/NCT07362225term=NCT07362225&rank=1 @bose_prithviraj @TaniaJain11 @Medscape @EHA_Hematology $KPTI's surprise data in HB improvement in MF will hurt $GSK's momelotinib. Would a combo with momelotinib have even better HB results @bose_prithviraj @doctorpemm @RaajitRampal @AaronGerds @MDmasarova @LindsayReinMD @TaniaJain11 @DrJoeScandura /210 https://t.co/I9rzv50WD9"
X Link 2026-01-25T18:41Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal $NVS will have to start new P3 for pelabresib Manifest-3 h/t @ByMadeleineA /324 https://x.com/kinatsofrim/status/1896633966226247801s=20 https://www.oncologypipeline.com/apexonco/novartis-perseveres-pelabresib Today at the TD Cowen healthcare conference analyst Marc Frahm asks $INCY's Pablo Cagnoni about their BET inhibitor for 2L and the markets dismissiveness. Pablo also mentioned that $NVS's pelabresib will need to do a completely new study. h/t $KPTI /181 https://t.co/xGBDLP9Acp"
X Link 2026-01-26T15:33Z [---] followers, [----] engagements
"$GMAB on losing streak ouch @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma $GMAB @Genmab has entered the $KPTI chat /295 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline"
X Link 2026-01-27T01:19Z [---] followers, [---] engagements
"$KPTI CEO and $GMAB EVP/CCO worked together at Ipsen and $KPTI CMO Reshma Rangwala is Genmab alumni. Synergies in MM and EC"
X Link 2026-01-27T01:59Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $GSK's momelotinib sales in Q4 $158mm small growth. $KPTI /325 https://x.com/kinatsofrim/status/1983561499185483940s=20 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma $GSK's momelotinib sales slowing down () in Q3 $146m vs."
X Link 2026-02-04T11:05Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $GSK CEO Luke Miels on Q4 call sound like they have something in mind. $KPTI /326 https://x.com/kinatsofrim/status/1816218892911665457s=20 Who will aquire $KPTI Since the MF & EC landscapes have rapidly evolved in the last few months I'm going to narrow the poll down to these four $INCY $MRK $GSK $AZN (GSK is unique in that it has synergies in all [--] indications MMMF & EC + RUBY PI @MirzaCPH is $KPTI Board member) https://x.com/kinatsofrim/status/1816218892911665457s=20"
X Link 2026-02-04T13:53Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA "IQQWiG concluded that the additional benefit of $GSK's momelotinib in this indication is "not proven" citing the companys deviaiton from the G-BA-defined comparator therapies and the lack of suitable supporoting evidence" /327 https://x.com/kinatsofrim/status/1922374810081903098s=20 https://www.navlindaily.com/article/29378/iqwig-finds-no-proven-additional-benefit-for-gsk-s-omjjara-in-myelofibrosis @bose_prithviraj @TaniaJain11 @Medscape @EHA_Hematology $KPTI's"
X Link 2026-02-04T14:22Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA Cantor Fitzgerald initiates $KPTI with Overweight rating. Cantor "assigns approx 70% probability of success for SENTRY p3 and believes a successful trial outcome would reposition $KPTI from a challenged MM player to a frontline MF combo contender" /329 https://www.investing.com/news/analyst-ratings/cantor-fitzgerald-initiates-karyopharm-stock-with-overweight-rating-93CH-4486527"
X Link 2026-02-05T11:42Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA If accurate that $GSK's momelotinib has low to minimal cytokine effects then $KPTI's selinexor would complement momelotinib well and can be initiated in patients with platelet counts below [-----]. /330 https://x.com/kinatsofrim/status/1922374810081903098s=20 @bose_prithviraj @TaniaJain11 @Medscape @EHA_Hematology $KPTI's surprise data in HB improvement in MF will hurt $GSK's momelotinib. Would a combo with momelotinib have even better HB results @bose_prithviraj"
X Link 2026-02-06T16:15Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $KPTI Throw in the phase [--] Xport-EC-042 (topline mid Q2) that's another $1b in sales. /333 https://x.com/kinatsofrim/status/1948428547976024540s=20 $KPTI Thank you Dr. Krivak @AHNtoday "I think SEINDO was I don't want say a sleeper trial. how did this slip by the radar. profound results. absolutely remarkable. tremendously exciting" h/t Dr. Gottfried Konecny @UCLAHealth Dr. Leslie Randall @VCUHealth and @OncLive https://t.co/lbqvKUllGp"
X Link 2026-02-08T00:45Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA $GSK's momelotinib: SIMPLIFY-1 JAKi-nave vs Rux showed similar NI TSS to rux. It did not meet the NI criterion for superior TSS50 comp. to rux it provided superior TI & reduced TB. SIMPLIFY-2 Post Rux vs BAT showed superior TSS & TI comp. to BAT. /334 https://x.com/kinatsofrim/status/1852391156027412786s=20 On yesterday's $KPTI KOL call PI Dr. John Mascarenhas talked about ruxolitinib and selinexor having no overlapping toxicities while other jak inhibitors $GSK"
X Link 2026-02-08T03:08Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA The FDA oddly gave $GSK's momelotinib approval for 1L when application was for 2L. Fast forward now the German's at IQWiG are challenging them (see earlier in thread #327) coupled with slowish sales (ibid #325). /335 https://x.com/kinatsofrim/status/1816218892911665457s=20 Who will aquire $KPTI Since the MF & EC landscapes have rapidly evolved in the last few months I'm going to narrow the poll down to these four $INCY $MRK $GSK $AZN (GSK is unique in that it has"
X Link 2026-02-08T03:37Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA With $KPTI SENTRY P3 topline early March CEO booked gig @LongwoodLeaders for March [--] /336 https://www.longwoodhealthcareleaders.com/miamiceo https://www.longwoodhealthcareleaders.com/miamiceo"
X Link 2026-02-08T11:41Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders Early SVR improvement results in bigger drop in Abs-TSS further SVR improvement produces less Abs-TSS True SVR/TSS relationship is curved pushing $KPTI SENTRY PoS from 70% to 80% bs"d. /337"
X Link 2026-02-09T18:16Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders $INCY CEO BD comment on Q4 call this morning. Bottom line: ruxolitinib makes up two-thirds of thier total revenue. They'll have to deal with several years of serious drop in revenue even IF by some miracle everything in their pipeline got approved. /338 https://x.com/kinatsofrim/status/1985400941315522864s=20 @RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat"
X Link 2026-02-10T14:52Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers If $KPTI's SENTRY reads out positive $INCY's MF franchise will be in trouble. and if SENTRY-2 is positive it over for them. /321 https://x.com/kinatsofrim/status/1985400941315522864s=20 https://x.com/kinatsofrim/status/1985400941315522864s=20"
X Link 2026-01-12T12:41Z [---] followers, [----] engagements
"New - New - @DBashIdeas https://t.co/LYjyEWrFB0 New - @DBashIdeas https://t.co/LYjyEWrFB0"
X Link 2026-02-04T19:38Z [---] followers, [----] engagements
"Last week Ron Gvili hyd was recovered so went for something new (Zuriman) for kiddush. Medium body earthy slight traces of hibiscus grated on apple bark lightly sweetened gribenes and faint notes of fig #KSbottles @minhagim Maybe online too though got this locally. Havent been able to fully relish and get in the zone π€·β @minhagim Maybe online too though got this locally. Havent been able to fully relish and get in the zone π€·β"
X Link 2026-02-06T20:53Z [---] followers, [---] engagements
"RT @kinatsofrim: @Yahrtzeits [--] Shvat: Rav Yechezkel Mazuz of Djerba - Netivot (1926-2022)"
X Link 2026-02-08T21:01Z [---] followers, [--] engagements
"Tell me your political views without telling me your political views (Robert Alter)"
X Link 2026-02-10T02:56Z [---] followers, [---] engagements
"New '' - " New - https://t.co/2g7yoGamz0 New - https://t.co/2g7yoGamz0"
X Link 2026-02-10T17:49Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders $KPTI Millennium picks up 5.5% of the company. /340"
X Link 2026-02-11T14:42Z [---] followers, [---] engagements
"I feel this"
X Link 2026-02-11T20:03Z [---] followers, [---] engagements
"@harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers @RaajitRampal @ByMadeleineA @LongwoodLeaders $KPTI on Q4 call CMO goes after $INCY /341 https://x.com/kinatsofrim/status/2010693715044577408s=20 @harrisoncn1 @peter_mpn @KartosThera @buysidebio @Biopharmaddict @bose_prithviraj @Blood_Cancers If $KPTI's SENTRY reads out positive $INCY's MF franchise will be in trouble. and if SENTRY-2 is positive it over for them. /321 https://t.co/yIYwUmPBk2 https://t.co/I6Fd8vw94K https://x.com/kinatsofrim/status/2010693715044577408s=20 @harrisoncn1 @peter_mpn"
X Link 2026-02-12T14:38Z [---] followers, [---] engagements
"New ' ' - New - @HQSatmar https://t.co/mv99hqPTAK New - @HQSatmar https://t.co/mv99hqPTAK"
X Link 2026-02-13T19:14Z [---] followers, [--] engagements
"@sahsan10 @alexforschner $KPTI Back in"
X Link 2026-02-13T21:19Z [---] followers, [--] engagements
"Hakham Zvi never used stunt doubles"
X Link 2024-08-26T03:01Z [---] followers, [---] engagements
"27 Av @Yahrtzeits: Reb Shmuel Tzvi Horowitz of Spinka aka Reb Hersheller (1921-1997). He was instrumental in his nephew R' Naftali Horowitz's life trajectory @EliLanger"
X Link 2024-09-01T21:15Z [---] followers, [----] engagements
"@endimem_music I wonder if Trump can make it through Bobby Lee's childhood story without flinching"
X Link 2024-09-04T00:57Z [---] followers, [---] engagements
"R' Michoel Sorotzkin makes a fascinating observation on the connection between Rav Avremel Ausband Ztl and the Meshech Chochma Rav Meir Simcha Ztl part [--] Rav Mordechai Willig bids a tearful goodbye to Rav Avremel Ausband his dear friend and neighbor of [--] years. https://t.co/UB5mZuftIy Rav Mordechai Willig bids a tearful goodbye to Rav Avremel Ausband his dear friend and neighbor of [--] years. https://t.co/UB5mZuftIy"
X Link 2024-09-08T18:29Z [---] followers, [----] engagements
"20 Elul @Yahrtzeits: Mekubal Rav Avraham Monsa (1912-2008)"
X Link 2024-09-23T19:24Z [---] followers, [---] engagements
"My favorite part of @DBashIdeas interview with Reb Tuvia @tenenbom"
X Link 2024-09-25T16:12Z [---] followers, [----] engagements
"More likely: [--] Elul @Yahrtzeits: R Yaakov Tam b. Meir. Rabenu Tam passed away on the eve of RH. I have on tradition when Rashi died RT heard a heavenly echo crying. I think the Luster of Israel was extinguished said RTs mother. And RT replied I will rekindle it. [--] Tamuz: R'Yaakov Ben Meir Tam of Romereau Rabbeinu Tam (1100-1171). One of the primary authors of the Tosafos commentary on the Gemara. Grandson of Rashi. He was called Tam due to his wholesomeness and righteousness. Some of his responsa are collected in Sefer Hayashar. https://t.co/UOpJ0BzZAx [--] Tamuz: R'Yaakov Ben Meir Tam of"
X Link 2024-10-02T00:36Z [---] followers, [----] engagements
"New from R' Yaakov Sasson (trigger warning @endimem_music R' Dovid @DBashIdeas gets a nice shout-out)"
X Link 2024-11-05T18:11Z [---] followers, [----] engagements
"@TheLastRefuge2 This should be read not once not twice but [---] times. We have a teaching reviewing ones studies [---] times ensures it won't be forgotten :) @DonaldJTrumpJr @EricTrump @elonmusk"
X Link 2024-11-11T22:30Z [---] followers, [---] engagements
"@allisonoconor reminds me of @stoolpresidente at the State Fair of Texas"
X Link 2024-11-14T18:18Z [---] followers, [--] engagements
"@krotchetygaon @endimem_music TR baller rolls up with trophy Mekubal at his side"
X Link 2024-11-20T16:26Z [---] followers, [--] engagements
"In Telz if you wanted to borrow Uncle Toms Cabin - R Lazer Gordons home was the right address"
X Link 2024-12-10T02:30Z [---] followers, [----] engagements
"@FrumTikTok According to the mothers narrative thats quite a misunderstanding about the style of haircut unless the barber was deaf and blind π€·β"
X Link 2024-12-13T02:59Z [---] followers, [----] engagements
"Nothing to see here; was a simple mistake. No deep secrets. β€"
X Link 2024-12-26T18:15Z [---] followers, [----] engagements
"Tonight 6th night of Chanuka is the @Yahrtzeits of Reb Pinchas Kehati (1910-1976). Author of the monumental "Mishnayos Mevoaros" (aka Kehati Mishnayos) @Yahrtzeits R Pinchos Kehati (though in the 6th candle was lit on [--] Teves): https://t.co/ycoxx8n1tl @Yahrtzeits R Pinchos Kehati (though in the 6th candle was lit on [--] Teves): https://t.co/ycoxx8n1tl"
X Link 2024-12-30T23:27Z [---] followers, [----] engagements
"New π: After many years working on Rashis torah comm. and the early supercommentaries. R Moshe Philip now released a volume analyzing all the places Ramban deals with Rashi @ek2220 @rashi_in @ChananyaBerman @DBashIdeas Thank you @ek2220 for bringing this to my attention ππ» https://t.co/qw5Bjf89BI @ek2220 @rashi_in @ChananyaBerman @DBashIdeas Thank you @ek2220 for bringing this to my attention ππ» https://t.co/qw5Bjf89BI"
X Link 2024-12-31T19:49Z [---] followers, [---] engagements
"@endimem_music For some reason that one rebbe who shines when it comes to these Rashis isn't respected by the other Rebbiem who skip them"
X Link 2025-01-03T03:26Z [---] followers, [----] engagements
"@TheLastRefuge2 Heads up Gowdy on the radio now with Judge Jeanine (paraphrasing) "I just went on a trip with my very good friend the incoming CIA director John Ratcliffe.""
X Link 2025-01-05T16:58Z [---] followers, [----] engagements
"@DBashIdeas"
X Link 2025-01-06T01:30Z [---] followers, [---] engagements
"@endimem_music Enough is enough we need a hashgacha entity to approve podcasts. Will call it "
X Link 2025-01-06T04:17Z [---] followers, [---] engagements
"@endimem_music Manic Menahse threw all his sister's american girl dolls into the chametz fire"
X Link 2025-01-06T05:04Z [---] followers, [----] engagements
"6 Teves @Yahrtzeits: R Sasson (b. Mordechai) Shinduch (1747-1830) sometimes nicknamed Adjmi. Rav in highly regarded mekubal and darshan payytan artisan and authored many seforim; later some were lost in a fire in 1860"
X Link 2025-01-07T03:07Z [---] followers, [---] engagements
"The story of the geirei tzedek Reb Moshe Hattori and his wife Tzipora of Shaare Chesed is truly amazing. non-stop mesiras nefesh both former Japanese pastors. to becoming a full fledged Gra'nik and a close student of Rav Shmuel Aurbach ztl @jacklanger do your thing"
X Link 2025-01-08T03:14Z [---] followers, [----] engagements
"R Yaacov de Illescas in his Imrei Noam quoted a Yerushalmi containing a suspicious ending. L Ginzberg said he only found this word-play in a note on Yad Ramah. S Lieberman in his personal copy of Gs comm. added in the margin Read: After Lieberman showed meπ"
X Link 2025-01-13T02:05Z [---] followers, [----] engagements
"mesivta struggles #438 Phzurrrrrxiptzkna Belaaz Oh okay. I get it now mesivta struggles #438 Phzurrrrrxiptzkna Belaaz Oh okay. I get it now"
X Link 2025-01-14T01:01Z [---] followers, [----] engagements
"@endimem_music @IraZlotowitz @GPARENCY Too many bachurim in the mid/upper twenties delaying entering the work force and instead pretending to learn three sedorim bec the fear of being stigmatized & shidduch prospects"
X Link 2025-02-13T00:12Z [---] followers, [----] engagements
"Unidentified avrech studying halachos of kosher birds and this happens This only happens to you once. π https://t.co/7c8WlKRrWm This only happens to you once. π https://t.co/7c8WlKRrWm"
X Link 2025-02-13T22:03Z [---] followers, [----] engagements
"The fact that RHS misremembered the details quoting from the original ToC -which doesnt appear in the newer ed.- only tells me he how great of a he is prob relying on his and that he would learn the maftechos too. (Attn seforim publishers: Keep the original)"
X Link 2025-02-26T19:50Z [---] followers, [---] engagements
"@TheLastRefuge2 "Pam Bondi is the Sean Hannity of U.S. Attorney Generals" - pure gold"
X Link 2025-02-28T03:31Z [---] followers, [---] engagements
"$KPTI $BMY $ONC (Beigene) https://x.com/kinatsofrim/status/1758575825689952644 $BMY picks up both $KPTI & @antengene one-two punch https://t.co/RShZm2KauC https://t.co/z83VaQhrs6 https://x.com/kinatsofrim/status/1758575825689952644 $BMY picks up both $KPTI & @antengene one-two punch https://t.co/RShZm2KauC https://t.co/z83VaQhrs6"
X Link 2025-04-09T00:19Z [---] followers, [---] engagements
"R Shmuel Palagi was compelled to print a resp. re. a halachic controversy that stirred in his community of Hamburg. Toward the end of this short vol. he raised other unrelated concerns [--] of them being his condemnation of the popular European poem sung @ end of Haggadah"
X Link 2025-04-18T00:52Z [---] followers, [----] engagements
"That time when the distinguished kabbalist Rashash wanted to be stringent following a Lurianic custom but acquiesced to -it seems- his wifes urging him to shave"
X Link 2025-05-20T17:10Z [---] followers, [----] engagements
"That time when Prof. Saul Lieberman was introduced to Yemenite jewry through the very learned but unassuming shamis/shamosh (custodian)"
X Link 2025-06-18T17:44Z [---] followers, [----] engagements
"@endimem_music Anachnu ma'aminim Fishy Swishy"
X Link 2025-06-26T01:20Z [---] followers, [----] engagements
"Casually obviates some dozen+ seforim on kelalei SA. No googling or OtzarH; leave your thoughts below"
X Link 2025-07-29T14:10Z [---] followers, [----] engagements
"$ONC (Beigene) @johnvoyler Jul [--] sold [-----] shares for a total value of $7.04mm. @BeOneMedicines @johnvoyler it's time. https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to the possibilities to make sure that we maximize the potential of Selinexor + Rux $INCY". /1 https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive"
X Link 2025-07-30T00:26Z [---] followers, [---] engagements
"From R Chaim Vitals son R Shmuel Casually obviates some dozen+ seforim on kelalei SA. No googling or OtzarH; leave your thoughts below. https://t.co/af8JEs7rUW Casually obviates some dozen+ seforim on kelalei SA. No googling or OtzarH; leave your thoughts below. https://t.co/af8JEs7rUW"
X Link 2025-07-30T14:31Z [---] followers, [----] engagements
"@GilStudent Conversely why are some pesukim in Megilas Esther read on Purim with an Eicha tune So Litvaks too would have some simchas Purim. Then why dont we read the whole Megila like that Bec that would already be holelus"
X Link 2025-08-04T03:47Z [---] followers, [---] engagements
"Reb Zelig in Beis Din @endimem_music"
X Link 2025-08-04T17:32Z [---] followers, [----] engagements
"@FieldSpeakerZDQ Oh absolutely its wild. Prob once a week i come across a new guy. Insanity. Have a whole theory about the phenomenon the why & the how and then the spiraling broader affects etc. but watevs not for here. Basically its mostly charlatanism with some kabbalah cosplay"
X Link 2025-08-15T18:09Z [---] followers, [---] engagements
"$RPRX Royalty Pharma to pay up to $950 million for royalties from $AMGN lung cancer drug. $KPTI CEO is also $AMGN alumni down-payment + two cvr's https://www.reuters.com/legal/litigation/royalty-pharma-pay-up-950-million-royalties-amgens-lung-cancer-drug-2025-08-25/ cont. Although a total BO from $AMGN isn't impossible. They bought Onyx/Kyprolis where $KPTI previous CEO MK was cmo. In reality it looks like $KPTI is betting it all on Endo and MF. MM is just better than nothing."
X Link 2025-08-26T20:41Z [---] followers, [----] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy @GabyHobbs @Stemline @Blood_Cancers @SocietyofHemOnc @mpdrc @mlieducation @MDmasarova @JamesPharma @Genmab @mroliverbarnes @JFK_America @CRTFund @TischCancer @bose_prithviraj @VCUHealth @OncLive $INCY CEO @ Evercore "BD like in any situation is going to be supplemental. It can be a multiplier of our growth. We'll do things that extend or strengthen the core & be really smart about how we use the"
X Link 2025-12-03T18:53Z [---] followers, [---] engagements
"@harrisoncn1 $KPTI Thank you Dr. Claire Harrison @harrisoncn1 /314 https://x.com/kinatsofrim/status/1752708130104865005s=20 $KPTI @AlbertBourla @MyOncology @BarryGreene Yeshiva week is over let's go. https://t.co/q0loycv6e8 https://x.com/kinatsofrim/status/1752708130104865005s=20 $KPTI @AlbertBourla @MyOncology @BarryGreene Yeshiva week is over let's go. https://t.co/q0loycv6e8"
X Link 2025-12-11T02:48Z [---] followers, [---] engagements
"@harrisoncn1 $KPTI Add'l important cmts. from @harrisoncn1 no ITP increase symptom response with seli mono striking we can be reasonably reassured excited for topline robust study design early sfty data reassuring no need to dose adjust dosing is straightforward /315"
X Link 2025-12-11T14:48Z [---] followers, [---] engagements
"@AaronRosenblum5 @DueDoctor Other possibilities. $INCY buying back rux rights from $NVS as @IloveIncyte wants to expand to the EU and this way they also settle lawsuit see link. Or $INCY buying selinexor rights from @Stemline to close on $KPTI https://casetext.com/case/novartis-pharma-ag-v-incyte-corp-12 https://casetext.com/case/novartis-pharma-ag-v-incyte-corp-12"
X Link 2024-11-15T16:31Z [---] followers, [----] engagements
"@RaajitRampal @clinadvances @doctorpemm @TaniaJain11 @Medscape @MKremyanskaya @doclucchesi @harrisoncn1 @VasNarasimhan @antengene @EricTokat @IcahnMountSinai @HealthTree @traviscooper93 @mpnadvocacy $KPTI CFO dialed up Centerview as she worked with them last year while at $LEGN Question: Why is CVP getting involved with $KPTI situation Acquisition $INCY $NVS $MRK $GSK $BMY $ABBV $RHHBY $SNY $AZN SOBI Dilution C11 /253 https://x.com/kinatsofrim/status/1947821628676837439 https://www.fiercepharma.com/pharma/legend-biotech-ceo-takes-close-look-business-amid-geopolitical-risk-ma-rumor"
X Link 2025-08-06T14:43Z [---] followers, [----] engagements
"$KPTI Thank you @MirzaCPH for all your valuable contributions over the years. $KPTI Board member and RUBY $GSK PI/KOL Dr. @MirzaCPH was @myESMO Italy June [----] "Predicting the Future" https://t.co/P84yJJqs3V $KPTI Board member and RUBY $GSK PI/KOL Dr. @MirzaCPH was @myESMO Italy June [----] "Predicting the Future" https://t.co/P84yJJqs3V"
X Link 2025-09-11T21:20Z [---] followers, [---] engagements
"In April @MirzaCPH became CMO at Acrivon Therapeutics. He didn't resign from $KPTI then. Why now Potential conflict with acquiring party https://x.com/kinatsofrim/status/1948428547976024540 https://ir.acrivon.com/news-releases/news-release-details/acrivon-therapeutics-appoints-world-renowned-oncology-key $KPTI Thank you Dr. Krivak @AHNtoday "I think SEINDO was I don't want say a sleeper trial. how did this slip by the radar. profound results. absolutely remarkable. tremendously exciting" h/t Dr. Gottfried Konecny @UCLAHealth Dr. Leslie Randall @VCUHealth and @OncLive https://t.co/lbqvKUllGp"
X Link 2025-09-12T01:32Z [---] followers, [---] engagements
"New " from Rav Yechezkel Mazuz ztl son of Rav Shlomo ztl https://www.bhol.co.il/news/1330434 @abekay2 @Yahrtzeits https://t.co/RsAQZdOOwr https://www.bhol.co.il/news/1330434 @abekay2 @Yahrtzeits https://t.co/RsAQZdOOwr"
X Link 2023-01-31T14:07Z [---] followers, [----] engagements
"@Yahrtzeits [--] Shvat: Rav Yechezkel Mazuz of Djerba - Netivot (1926-2022) New " from Rav Yechezkel Mazuz ztl son of Rav Shlomo ztl https://t.co/ra1FniIkeT https://t.co/bJTe8tjgbW New " from Rav Yechezkel Mazuz ztl son of Rav Shlomo ztl https://t.co/ra1FniIkeT https://t.co/bJTe8tjgbW"
X Link 2023-02-13T15:56Z [---] followers, [----] engagements
"https://youtu.be/RKgcb-QjYQ4 https://youtu.be/RKgcb-QjYQ4"
X Link 2023-02-19T19:27Z [---] followers, [---] engagements
"@minhagim Maybe online too though got this locally. Havent been able to fully relish and get in the zone π€·β"
X Link 2024-01-05T18:21Z [---] followers, [---] engagements
"$KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to the possibilities to make sure that we maximize the potential of Selinexor + Rux $INCY". /1 From Cantor: biotech M&A transactions took an avg of [----] mos in [----]. From start of deals talks to deal announcement. Assume deal talks start after data confirming this and how long after data. https://t.co/FrVTkJiekN From Cantor: biotech M&A transactions took an avg of [----] mos in [----]. From start of deals talks to deal"
X Link 2024-03-14T20:36Z [---] followers, 40.5K engagements
"New - @HQSatmar"
X Link 2025-03-30T19:54Z [---] followers, [----] engagements
"$KPTI Warm welcome to @alexforschner https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to the possibilities to make sure that we maximize the potential of Selinexor + Rux $INCY". /1 https://x.com/kinatsofrim/status/1768375601847501223 $KPTI MF timeline. P1 update at ASH Dec. [----] then April [----] at AACR initiates P3 June [----] receive FT July [----] (received OD in Oct. 2022) Nov. [----] CEO @ Jefferies "Very open to"
X Link 2025-05-16T00:29Z [---] followers, [---] engagements
"@sahsan10 @alexforschner Did you guys buyout the $25m note due in Oct. at a discount"
X Link 2025-05-16T22:07Z [---] followers, [---] engagements
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