#  @drterrysimpson Dr Terry Simpson Dr Terry Simpson posts on X about dr, in the, food, if you the most. They currently have [------] followers and [---] posts still getting attention that total [-------] engagements in the last [--] hours. ### Engagements: [-------] [#](/creator/twitter::19565716/interactions)  - [--] Week [---------] +67% - [--] Month [---------] +238% - [--] Months [---------] +217,259% - [--] Year [---------] -2.60% ### Mentions: [--] [#](/creator/twitter::19565716/posts_active)  - [--] Month [---] +88% - [--] Months [---] +4,500% - [--] Year [---] +1,369% ### Followers: [------] [#](/creator/twitter::19565716/followers)  - [--] Week [------] +1.90% - [--] Month [------] +25% - [--] Months [------] +72% - [--] Year [------] +73% ### CreatorRank: [------] [#](/creator/twitter::19565716/influencer_rank)  ### Social Influence **Social category influence** [finance](/list/finance) 7.69% [countries](/list/countries) #957 [celebrities](/list/celebrities) 1.28% [stocks](/list/stocks) 1.28% **Social topic influence** [dr](/topic/dr) #23, [in the](/topic/in-the) #288, [food](/topic/food) #5628, [if you](/topic/if-you) #4337, [carnivore](/topic/carnivore) #239, [science](/topic/science) 5.77%, [health](/topic/health) #3126, [data](/topic/data) #8, [countries](/topic/countries) #13, [the most](/topic/the-most) 3.85% **Top accounts mentioned or mentioned by** [@anonemus349832](/creator/undefined) [@new_york_steak](/creator/undefined) [@skunk_bucketss](/creator/undefined) [@souaprotector](/creator/undefined) [@diy_tardis](/creator/undefined) [@drjonl](/creator/undefined) [@albowers11](/creator/undefined) [@qwixxf](/creator/undefined) [@voidmillennia](/creator/undefined) [@curiousthrifty](/creator/undefined) [@limitededish970](/creator/undefined) [@sandmanrt](/creator/undefined) [@sgonzalez37054](/creator/undefined) [@suzannereads](/creator/undefined) [@lookingatyoum8](/creator/undefined) [@ralphsmorra](/creator/undefined) [@vincristine](/creator/undefined) [@pjungar](/creator/undefined) [@grok](/creator/undefined) [@hrhted](/creator/undefined) **Top assets mentioned** [Costco Wholesale Corporation (COST)](/topic/costco) ### Top Social Posts Top posts by engagements in the last [--] hours "There are many reasons young people get colon cancer including getting antibiotics as a child genetic issues and even if you have done everything right you can get colon cancer. It isn't about a food fight - it is about early screening and if you feel something is off - unexplained iron deficiency anemia blood in the stool or unexplained weight loss - it is time to get a colonoscopy Beautiful Actor James Van der Beek ate lots of fruits and vegetables lots of smoothies. Then he got colon cancer. Its so sad so senseless. Maybe humans are not supposed to eat so many plants so many superfoods so" [X Link](https://x.com/drterrysimpson/status/2022090523184697659) 2026-02-12T23:28Z 14.2K followers, [----] engagements "The idea that a carnivore diet prevents autoimmune disease is a claim in search of evidence. Autoimmune diseases are heterogeneous genetically influenced immune-mediated conditions with complex environmental triggers. There are no randomized controlled trials showing that a meat-only diet prevents the onset of Crohns lupus rheumatoid arthritis multiple sclerosis or any other autoimmune disease. None. Elimination diets can reduce symptoms in selected patientsbecause removing certain triggers may reduce immune activationbut symptom modulation is not prevention and short-term improvement is not" [X Link](https://x.com/drterrysimpson/status/2022091353883296143) 2026-02-12T23:32Z 14.2K followers, [----] engagements "Were being told hospitals are flooded with GLP-1 complications and that were at the tip of the iceberg. Ive been a bariatric surgeon long enough to remember these drugs when they were still in trials. Ive prescribed them. Ive monitored patients on them. And when the ER had a question about one of my patients on a GLP-1 they called me. I am not seeing a flood. What I see every single shift are the consequences of untreated obesity: heart failure uncontrolled diabetes infections sleep apnea crises fatty liver disease progressing quietly toward cirrhosis. That is the deluge. Yes GLP-1" [X Link](https://x.com/drterrysimpson/status/2022416296873463852) 2026-02-13T21:03Z 14.2K followers, 1.1M engagements "Puerto Ricans are U.S. citizens not guests not freeloaders not an anecdote. Roughly 40% receive federal food assistanceabout the same order of magnitude as the poorest counties in Mississippi Alabama and Louisiana. Poverty is not a foreign policy problem; its an American one. Sneering at the island while ignoring the Deep South is prejudice with a spreadsheet allergy. Fun fact about Puerto Rico: half the island is on a food stamp program paid for by US citizens Fun fact about Puerto Rico: half the island is on a food stamp program paid for by US citizens" [X Link](https://x.com/drterrysimpson/status/2021073275552661641) 2026-02-10T04:06Z 14.2K followers, 97.7K engagements "I can find two publications with your name on them. I can find no evidence of a doctorate no formal training in medicine and no clinical responsibility for patients. Yet you position yourself as an authority on how causation is determined in medicine. What you demonstrated in that debate was not methodological rigor. It was rhetorical absolutism redefining terms until no evidence could ever qualify. That is not how causation is determined in clinical science. It is how arguments are insulated from falsification. You may declare victory. Ill continue practicing medicine under standards" [X Link](https://x.com/drterrysimpson/status/2022089917413962101) 2026-02-12T23:26Z 14.2K followers, [----] engagements "Obesity is a chronic disease. Like hypertension or diabetes when you stop treatment you should anticipate its return. This isnt failure. Its biology. The benefits of weight loss medications may be shorter-lived than originally hoped. Those who stop taking GLP-1s may return to pre-treatment levels of body weight and heart disease risk within two years. https://t.co/NFy9tr2o8i https://t.co/FTqblEEA2p The benefits of weight loss medications may be shorter-lived than originally hoped. Those who stop taking GLP-1s may return to pre-treatment levels of body weight and heart disease risk within two" [X Link](https://x.com/drterrysimpson/status/2022092368175149374) 2026-02-12T23:36Z 14.2K followers, 17K engagements "GLP-1s arent marketed as a cure for obesity and obesity isnt a condition we cure in the first place. Obesity is a chronic relapsing metabolic disease much like hypertension or asthma. When treatment stops the biology returns. Thats not failure thats physiology. Comparing GLP-1s to a crutch misses the mechanism. These medications act on hypothalamic appetite regulation gastric emptying insulin signaling and reward pathways. They address the underlying neurohormonal drivers of weight regain the very forces that make long-term weight loss so difficult. Lifestyle remains foundational. Nutrition" [X Link](https://x.com/drterrysimpson/status/2022367397102129417) 2026-02-13T17:48Z 14.2K followers, 21.1K engagements "Why are younger people getting colon cancer https://open.substack.com/pub/tsimpson/p/why-are-younger-people-getting-colonr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true https://open.substack.com/pub/tsimpson/p/why-are-younger-people-getting-colonr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true" [X Link](https://x.com/drterrysimpson/status/2022444510006120752) 2026-02-13T22:55Z 14.2K followers, [----] engagements "As a bariatric surgeon Ive seen what untreated obesity does diabetes heart disease sleep apnea joint destruction. GLP-1 medications are tools that treat the neurohormonal drivers of appetite. If you withdraw therapy weight often returns because chronic diseases relapse without ongoing management. Thats medicine. Not literature" [X Link](https://x.com/drterrysimpson/status/2022456767888920986) 2026-02-13T23:44Z 14.2K followers, 19.8K engagements "GLP-1 medications have given people something they have not had in decades: hope grounded in biology. For the first time patients feel hunger quiet. Food noise softens. The constant metabolic push to regain weight eases. That is not cosmetic that is neuroendocrinology working the way it should. Hope matters. And it is real. But to claim obesity is not a chronic disease is to ignore the very biology that makes GLP-1s effective. When weight is lost the body does not applaud. Ghrelin rises. Leptin falls. Energy expenditure drops. Appetite circuits amplify. That adaptive response persistent" [X Link](https://x.com/drterrysimpson/status/2022686789321003426) 2026-02-14T14:58Z 14.2K followers, 12.4K engagements "I dont believe prescription medications should be marketed direct-to-consumer. Full stop. If a company can afford a Super Bowl commercial it can afford to lower the price of the drug. We are absolutely being gouged and the ad budget is part of that. Redirect that money to patients instead of prime time. Even telehealth companies like Ro which dont manufacture the drugs but sometimes rely on compounded versions exist in the vacuum created by cost and access barriers. I strongly dislike compounded GLP-1s. Theyre not FDA-approved formulations. But I understand why patients chase them when the" [X Link](https://x.com/drterrysimpson/status/2022689259589951798) 2026-02-14T15:07Z 14.2K followers, [----] engagements "Ah another denier - COVID causes long covid and mRNA is not gene therapy perhaps you should learn some basic biology. MRNA does not integrate into your DNA unless you have reverse transcriptase that some viruses use - like HIV. The mRNA does cause a manufacture of proteins for a brief period of time then it is degraded by the cell. That you can see immune proteins against those proteins doesnt mean they are still there it means the immune system is doing its job. - that is your 6th grade biology lesson for the day There is no long COVID. There is only that you were injected with an" [X Link](https://x.com/drterrysimpson/status/2022700289749590319) 2026-02-14T15:51Z 14.2K followers, [----] engagements "Weight regain after stopping a GLP-1 isnt a failure but to be clear: Yes behavior matters. Yes environment matters. Yes psychological drivers matter. But obesity does not begin as a purely moral or lifestyle defect and then later become metabolic. From the earliest stages of weight gain neurohormonal adaptation begins. Leptin signaling shifts. Ghrelin dynamics change. Energy expenditure subtly declines. Reward circuitry adapts. The body starts defending the higher weight. Thats biology not weakness. GLP-1 medications dont replace lifestyle change. They lower the biologic resistance to it." [X Link](https://x.com/drterrysimpson/status/2022701441010516122) 2026-02-14T15:56Z 14.2K followers, [----] engagements "When Influencers Replaced Scientists https://open.substack.com/pub/tsimpson/p/when-influencers-replaced-scientistsr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true https://open.substack.com/pub/tsimpson/p/when-influencers-replaced-scientistsr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true" [X Link](https://x.com/drterrysimpson/status/2010143770638188744) 2026-01-11T00:16Z 14.2K followers, 25.5K engagements "Yeah thats not how credibility works. Calling someone a leading voice does not make it soespecially when the work in question repeatedly misuses data ignores denominators invents excess deaths and fails basic epidemiology. A few reality checks: Nicolas Hulscher is not a physician and has no formal training in epidemiology. Substack is not a credential. Rebranding blog posts as data analysis does not turn ecological fallacies and spreadsheet errors into science. Being affiliated with advocacy groups like the McCullough Foundation signals ideology first evidence second. Translating complex" [X Link](https://x.com/drterrysimpson/status/2015995786522460427) 2026-01-27T03:50Z 13.8K followers, 40.9K engagements "Ah yesthe classic conspiracy where millions of doctors and pharmacists across every country secretly agree to keep people sic by not recommending a cheap vitamin anyone can buy at Costco. A few facts for the adults in the room: Simon Goddek mistakes bravado for evidence. Doctors dont lose money when your vitamin D is normal. Thats not how medicine or math works. [----] IU daily long-term is not benign. Hypercalcemia kidney stones and kidney injury are well-documented. Large randomized trials show no extra benefit from pushing levels high once deficiency is corrected. Although there is a down" [X Link](https://x.com/drterrysimpson/status/2015997840460534188) 2026-01-27T03:58Z 13.7K followers, 60.5K engagements "This is profoundly misleading and borders on defamatory. Hospitals do not profit from harvesting organs. Organ procurement is handled by independent nonprofit Organ Procurement Organizations (OPOs) under federal law. Hospitals are reimbursed for the care of living patients not for organs. Transplants are cost centers not cash cows. They are labor-intensive heavily regulated outcome-tracked and often reimbursed below cost once long ICU stays complications and lifetime immunosuppression are accounted for. Cancer is not a business line. It is a diagnostic category spanning hundreds of diseases" [X Link](https://x.com/drterrysimpson/status/2016249588840333409) 2026-01-27T20:38Z 13.8K followers, [----] engagements "South Carolina now leads the nation in measles cases: [---] and counting. This didnt happen because the virus changed. It happened because vaccination stopped. Hundreds quarantined. Federal aid deployed. Elimination status at risk. It did not happen because South Carolina is flooded with people from across the border with measles except the unvaccinated Americans who went overseas and brought it back. This is not a mystery. It is the predictable outcome of treating anecdotes influencers and onions as substitutes for public health. https://twitter.com/i/web/status/2016645828128157983" [X Link](https://x.com/drterrysimpson/status/2016645828128157983) 2026-01-28T22:53Z 13.7K followers, [----] engagements "Listing PubMed papers is not an argument; its rsum worship. Peter McCullough published extensively before [----] in cardiology. So did thousands of other competent specialists. That history does not confer authority in virology immunology epidemiology or vaccine safety nor does it grant a lifetime exemption from error. His current posture however is not merely outside his expertiseit is actively anti-science: rejection of population-level outcome data elevation of anecdotes over controlled evidence and a conspiratorial framing that treats consensus as corruption rather than the hard-won product" [X Link](https://x.com/drterrysimpson/status/2016744886792601736) 2026-01-29T05:27Z 13.7K followers, [----] engagements "You cannot blame Robert F. Kennedy Jr. alone for those choicesbut you also cant pretend he was absent. For years he was one of the most visible figures in the anti-vaccine and anti-MMR movement promoting claims that contradicted overwhelming evidence and helping normalize distrust of routine childhood vaccination. And when outbreaks began appearing he had a clear opportunity to change course. From a powerful bully pulpit he could have urged vaccination emphasized community protection and helped close immunity gaps. He did not. So no this isnt the result of one man or one moment. But he" [X Link](https://x.com/drterrysimpson/status/2016996747881615685) 2026-01-29T22:07Z 13.7K followers, [----] engagements "There is no species-appropriate carnivore diet for humanswere omnivores by anatomy enzymes anthropology and outcomes data. If carnivore truly fixed appetite regulation and insulin resistance GLP-1s wouldnt outperform it in randomized trials. Biology isnt impressed by ideology. @drterrysimpson Absolutely advocate the species appropriate diet for humans which is carnivore. you wouldn't need GLP-1 on a carnivore diet @drterrysimpson Absolutely advocate the species appropriate diet for humans which is carnivore. you wouldn't need GLP-1 on a carnivore diet" [X Link](https://x.com/drterrysimpson/status/2017609316573057348) 2026-01-31T14:42Z 13.8K followers, [----] engagements "High triglycerides are driven by energy surplus and insulin resistancewith major contributors including refined carbohydrates alcohol obesity genetics and metabolic disease. Dietary fat does not directly raise triglycerides but saturated fat increases ApoB and LDL which predicts cardiovascular events. Metabolism isnt a bacon-vs-carbs slogan; its measurable physiology. Might I suggest a course in basic physiology @drterrysimpson High trigs are caused by a carb diet not by Bacon and butter https://t.co/FbwuGGauAB @drterrysimpson High trigs are caused by a carb diet not by Bacon and butter" [X Link](https://x.com/drterrysimpson/status/2017614120812744921) 2026-01-31T15:01Z 13.8K followers, [----] engagements "Facultative carnivore is an ecological feeding descriptor not a biological or taxonomic classification. It describes animals that can rely heavily on meat when needed but are not restricted to it. Humans are classified biologically and anthropologically as omnivoresby dentition enzymes gut length isotopes and population outcomes. Flexibility identity. Survival capacity species definition. You wishing to be a carnivore doesn't make it true - @drterrysimpson False. Facultative Carnivore is a biological classification of which the genus homo is a member. You confuse obligate with facultative." [X Link](https://x.com/drterrysimpson/status/2017618310213603744) 2026-01-31T15:17Z 13.7K followers, [----] engagements "You continue to misinterpret what I say by pulling lines out of context and then arguing against claims I didnt make. I did not say carnivore diets cause hypertriglyceridemia. I stated the uncontroversial fact that severe hypertriglyceridemia causes pancreatitis. Reversing that is your error. Yes low-carbohydrate diets can lower triglycerides in some insulin-resistant patients. That does not make high-saturated-fat diets universally safe. In many phenotypeshepatic steatosis genetic dyslipidemia baseline hypertriglyceridemiasaturated fat increases liver fat VLDL output ApoB and triglyceride" [X Link](https://x.com/drterrysimpson/status/2017623882455519512) 2026-01-31T15:39Z 14.1K followers, [----] engagements "Peter Attia now appears in released Epstein-related emails. When a public figure is connected to material involving a known child predator transparency matters. If there is nothing to hide the simplest response is to release the emails in full. The public deserves to know: What he knew When he knew it And if he was aware of child predation whether he followed the ethical and legal duty as a physician to report it This is not about guilt by association. It is about accountability professional ethics and trust. When patients are paying extraordinary fees for access and credibility those" [X Link](https://x.com/drterrysimpson/status/2017717659559997696) 2026-01-31T21:52Z 13.9K followers, 75.9K engagements "As a Californian I wouldnt trade a state with the highest peak in the continental US for one whose highest point is a landfill with zoning approval. Now lets do math not vibes. California is the 4th largest economy on Earth. Bigger than Germany. Bigger than Japan. Florida isnt in the same sentence. California is a net donor to the federal government. We send tens of billions more to DC than we get back. Florida is a net taker. You cash the checks we write. California: Worlds leading innovation economy Produces 14% of US GDP Feeds powers entertains and funds the country Ports that move the US" [X Link](https://x.com/drterrysimpson/status/2017723558588543243) 2026-01-31T22:15Z 13.9K followers, 564K engagements "@MasalaFry69 @PaulCarpFisher Tell me youve never taken a course in epidemiology or biostatistics without telling me" [X Link](https://x.com/drterrysimpson/status/2017970004755689491) 2026-02-01T14:35Z 13.7K followers, [--] engagements "@OminousTheTruth Best public schools 4th largest economy in the world 75% of agriculture 37% of new businesses in the US best health care- its not just the geography we invest in people and pull people up" [X Link](https://x.com/drterrysimpson/status/2017972656050745590) 2026-02-01T14:45Z 13.9K followers, 15.3K engagements "Calling fiber inflammatory is a mechanistic fairy tale told by people who dont read outcome data. Populations that eat more fiber live longer have less heart disease less diabetes and less colon cancer. If fiber truly blocked vitamins and bile acids in any clinically meaningful way deficiency and harm would be obvious in decades of cohort data. They arent. This isnt heresy its just evidence. When your argument collapses at the level of population outcomes its ignorance with confidence. @drterrysimpson Fibre is bad for us. It's inflammatory blocks the absorption of fat soluble vitamins A D E" [X Link](https://x.com/drterrysimpson/status/2018113364128677950) 2026-02-02T00:04Z 13.8K followers, [----] engagements "Fiber isnt an essential nutrient is a semantic dodge not a scientific argument. Neither is exercise sunlight or sleep essential in the deficiency-disease sense yet lacking them reliably shortens lives. Fiber doesnt cause a deficiency syndrome; it prevents diseases. When you reduce nutrition to scurvy logic and ignore population outcomes youre being deliberately obtuse. https://twitter.com/i/web/status/2018114241014960610 https://twitter.com/i/web/status/2018114241014960610" [X Link](https://x.com/drterrysimpson/status/2018114241014960610) 2026-02-02T00:08Z 13.8K followers, [----] engagements "Another Gary Brecka wellness fortune cookie dressed up as endocrinology. Cortisol is regulated by the HPA axis not by mineral vibes. There is NO clinical evidence that sea salt water or vague electrolyte gaps normalize pathological cortisol. Magnesium may help sleep in deficient patientsnothing more. If high cortisol were fixed by sunlight breathing and salt Cushings syndrome wouldnt exist and endocrinologists would be out of work. Mechanisms without outcomes are not medicine but Gary is doing what he does best - making up diseases and then he does the marketing. High cortisol fixes: 1." [X Link](https://x.com/drterrysimpson/status/2018192220046942590) 2026-02-02T05:18Z 13.9K followers, [----] engagements "Posting a Zenodo PDF doesnt overturn decades of population data. Aluminum adjuvants dont cause autism. This claim survives only where peer review is avoided. Aluminum adjuvants can and do cause autism: https://t.co/JI2zReg7ce @ChildrensHD @CHDTVLive @SecKennedy @HHS_Jim Aluminum adjuvants can and do cause autism: https://t.co/JI2zReg7ce @ChildrensHD @CHDTVLive @SecKennedy @HHS_Jim" [X Link](https://x.com/drterrysimpson/status/2018192659190620584) 2026-02-02T05:20Z 13.7K followers, [----] engagements "Longevity gurus sell certainty. Science sells boring wins. Real longevity isnt peptides rapamycin cosplay ice baths or supplement stacks with no human outcome data. What actually works in humans: Mediterranean or DASH eating patterns Normal blood pressure ApoB [--] mg/dL (lower if high risk) Dont smoke Dont drink alcohol Move your body sleep repeat There is no biohack https://twitter.com/i/web/status/2018339061413613865 https://twitter.com/i/web/status/2018339061413613865" [X Link](https://x.com/drterrysimpson/status/2018339061413613865) 2026-02-02T15:01Z 13.9K followers, 19.8K engagements "Claim (repeated by RFK Jr): The Amish dont have autism because they dont vaccinate based on Dan Olmsteds study. Reality: Olmsted never conducted a study no screening no records no diagnostics no peer review. Just anecdotes. When Amish communities were actually examined autism rates were the same as other populations. If no one looks you can make up anything. Claim fails. Data wins. https://twitter.com/i/web/status/2018712206960136255 https://twitter.com/i/web/status/2018712206960136255" [X Link](https://x.com/drterrysimpson/status/2018712206960136255) 2026-02-03T15:44Z 13.7K followers, 55.3K engagements "Facts that dont go away: Statins inhibit HMG-CoA reductase yes the mevalonate pathway and that mechanism is exactly why they work. The downstream effects ( isoprenoids prenylation) have been studied for decades. This is not hidden or denied. Large outcome trials and meta-analyses (CTT Collaboration Cochrane JAMA Lancet) show clear reductions in MI stroke and CV mortality proportional to LDL/ApoB lowering. Claims of manipulated data collapse under replication: benefits appear across populations sponsors and trial designs. If statin trials were sham science we wouldnt see: Consistent" [X Link](https://x.com/drterrysimpson/status/2018723221538025729) 2026-02-03T16:28Z 13.8K followers, [----] engagements "The most nutrient dense - you hear this nonsense from everyone who eats carnivore - and when they say nutrient dense what do they mean Iron - we only can use so much. Choline something the body makes. Is it nutrient dense with anti-oxidants - nope magnesium - no. Want to go down a list of course they don't. But they think eating a steak is manly and eating vegetables is not - or they have not gotten out of their grade school habit of rejecting them. Grow up eat a balanced diet and stop thinking you are doing well - you are not. @vhs0 @drterrysimpson I'm eating the most nutrient dense food" [X Link](https://x.com/drterrysimpson/status/2018736828136947800) 2026-02-03T17:22Z 13.9K followers, 13.9K engagements "Nice duck You want some point by point of her claims - yet again. This is a textbook case of mechanism laundering.Yes statins inhibit HMG-CoA reductase and touch the mevalonate pathway. Thats been known for 40+ years. Listing downstream intermediates (FPP GGPP dolichol heme A IPP) is not a revelation. Its biochemistry cosplay unless you connect it to hard clinical the problem for the argument: RCT reality beats pathway poetry. Across dozens of large blinded statin RCTs (hundreds of thousands of patients) we see consistent reductions in MI stroke and all-cause mortality. If these pathway" [X Link](https://x.com/drterrysimpson/status/2018780350433169505) 2026-02-03T20:15Z 13.9K followers, [----] engagements "No proper human diet was not a claim of chaos it was a rebuttal to dietary absolutism. If carnivore were the proper human diet populations eating fiber-rich omnivorous diets wouldnt have the longest lifespans and lowest cardiometabolic disease. Biology refutes the slogan. Outcomes finish the argument. "First there is no proper human diet." Okay. Got it. Every other species got one. but well you should just take this dude's pills and adviceno matter how hard they are to swallowbecause humans don't have a diet. Wait. dammit did I fall for another one of those satire "First there is no proper" [X Link](https://x.com/drterrysimpson/status/2018781180750127481) 2026-02-03T20:18Z 13.7K followers, [----] engagements "This isnt diet nihilism or absolutism its evolutionary reality. Humans didnt evolve one rigid diet; we evolved flexibility within physiological bounds. When tested against outcomes fiber-containing omnivorous diets repeatedly outperform exclusionary extremes. @drterrysimpson It is not a rebuttal of diet absolutism; it is diet absolutism. And it flies in the face of science in the same way as veganism and carnivorism @drterrysimpson It is not a rebuttal of diet absolutism; it is diet absolutism. And it flies in the face of science in the same way as veganism and carnivorism" [X Link](https://x.com/drterrysimpson/status/2018783511461998699) 2026-02-03T20:27Z 13.9K followers, [---] engagements "Yes similar to Lovastatin first generation statin. Monacolin K has all of the side effects of any statin as a first generation it had the most and not as efficacious as later ones. Buying red rice yeast is about 20-40 dollars while my Crestor costs less than a dollar a month has fewer side effects lowers LDL more decreased risk of cardiovascular events and [--] % decreas in the risk of dementia. @YatYas1070 @drterrysimpson This is monacolin K. Please reply with the structure of monacolin K from red yeast: https://t.co/T5ryCEbLwr @YatYas1070 @drterrysimpson This is monacolin K. Please reply with" [X Link](https://x.com/drterrysimpson/status/2018797140097843614) 2026-02-03T21:22Z 13.9K followers, [----] engagements "Inuit mummies show atherosclerosis. Modern Inuit biology is well studied. Even today among Alaska Native populationsdespite better infant survivallife expectancy remains below the U.S. average. This isnt conjecture. Its population data. Survivorship bias longevity. @drterrysimpson I've done the work. Perhaps you should as you are the one in error. Hunter-gatherers who survive childhood typically live to be old: their most common age of death is between sixty-eight and seventy-two and most become grandparents or even great-grandparents. There's been @drterrysimpson I've done the work. Perhaps" [X Link](https://x.com/drterrysimpson/status/2018834547698471078) 2026-02-03T23:50Z 13.9K followers, [----] engagements "This is mechanism laundering. It strings together true chemistry terms to imply clinical harm that does not show up in human outcomes. 1) Saturated fat has no double bonds so its stable True. Irrelevant. Chemical stability in a test tube biological effect in humans. 2) PUFAs have double bonds that oxidize into lipid peroxides Partly true in vitro. But in living humans: PUFAs are packaged in lipoproteins Protected by antioxidants (vitamin E glutathione enzymes) Rapidly repaired and turned over If this claim were true at scale PUFA intake would correlate with higher disease and mortality. It" [X Link](https://x.com/drterrysimpson/status/2019039508776284648) 2026-02-04T13:25Z 13.7K followers, [----] engagements "Whats actually wrong with the chart [--]. Vitamin A bait-and-switch Beef liver is loaded with preformed retinol Kale contains beta-carotene a regulated precursor The body down-regulates beta-carotene conversion when stores are adequate. Retinol No such brake toxicity risk with regular liver intake. Nutrition highest number wins [--]. Portion distortion Most of these charts compare: [---] g beef liver (a pharmacologic dose) [---] g raw kale (not how people eat it) Nobody eats liver daily at that dose without consequences. Not to mention it tastes vile. [--]. Selective vitamin scoring They highlight: B12" [X Link](https://x.com/drterrysimpson/status/2019067571807588389) 2026-02-04T15:16Z 13.9K followers, [----] engagements "Calling me a poor student isnt evidence. And that quote doesnt prove ancestral diets = no heart disease. In Alaska Native/Inuit data (that I review for our tertiary system): some eat traditional some dontbut vascular disease isnt new and life expectancy still trails the Lower [--]. Economic progress doesnt require diabetes/CVDbut neither does it erase biology infection burden trauma smoking housing and access. @drterrysimpson @michael_trumper Again you are wrong. You claim your knowledge comes from your anthropology backgroundbut you must have been a poor student. As I already posted from one" [X Link](https://x.com/drterrysimpson/status/2019112469583856083) 2026-02-04T18:15Z 13.9K followers, [----] engagements "Ancestral diet = no CVD is a slogan not a mechanism. Low-CVD groups share a risk profile: low ApoB/LDL high activity low smoking/BP/obesity minimal ultra-processed foods. The cleanest causal evidence in humans remains lifelong low ApoB/LDL (incl. PCSK9 LOF). Insults arent data. I've read the whole paper and all the related papers and an enormous amount of the research that gives it context. Like what do we know causes CVD and obesity in humans that these people (and every other ancestral group with low CVD) doesn't eat Unlike you who continues to I've read the whole paper and all the related" [X Link](https://x.com/drterrysimpson/status/2019191868760998072) 2026-02-04T23:30Z 13.9K followers, [----] engagements "Calling this ignorance requires pretending history diagnostics and epidemiology dont exist. Yes myocardial infarction can be identified at autopsy todaybecause we now know what to look for. In [----] physicians did not. There were no ECGs no cardiac enzymes no coronary angiography and MI was not a standard diagnostic category. Most events were labeled sudden death heart failure or missed entirely. And noautopsy practice at one hospital was not universal medicine. Autopsy rates varied wildly by region hospital culture and consent. A Massachusetts teaching hospital is not a proxy for the United" [X Link](https://x.com/drterrysimpson/status/2019398270108274796) 2026-02-05T13:10Z 13.9K followers, [----] engagements "And someone who calls carbs evil - imagine the healthiest people in the world and longest living dont know this But this fellow does - amazing You know what else improves weight control retard Knock off the carbs retard. You know what else improves weight control retard Knock off the carbs retard" [X Link](https://x.com/drterrysimpson/status/2019456537467421145) 2026-02-05T17:02Z 13.7K followers, [----] engagements "Serious mental illness isnt cured by a diet. Ketogenic diets are being studied as possible adjuncts under medical supervisionnot as replacements for psychiatric care. If you have bipolar disorder or schizophrenia seek evidence-based treatment not internet nutrition advice. RFK Jr.: Dr. Pollan up at Harvard has cured schizophrenia using keto diets. here are studies right now that I saw two days ago where people lose their bipolar diagnosis by changing their diet. https://t.co/pGuMghJKPa RFK Jr.: Dr. Pollan up at Harvard has cured schizophrenia using keto diets. here are studies right now that" [X Link](https://x.com/drterrysimpson/status/2019462759935844814) 2026-02-05T17:26Z 13.8K followers, [----] engagements "Yes debate someone- always the cry of someone who doesnt want to do the hard work of reading the literature no they want to score points with logic - show the data not the dogma and if those peer reviewed studies contradict then let a new model arise - until then let the adults talk Well dickwad. Why not live debate my friend 'Baldy'. He will tear you seven new assholes he's a cardiovascular pathophysiologist btw. In this objective reality what I said is STILL CORRECT and you have NOT refuted it retard. You have repeated your incorrect opinion again. Well dickwad. Why not live debate my" [X Link](https://x.com/drterrysimpson/status/2019464459732021327) 2026-02-05T17:33Z 13.7K followers, [----] engagements "When your argument is this one guy is healthy youre not doing scienceyoure doing storytelling. Nutrition is evaluated in populations over decades with hard endpoints. Evidence beats vibes.and education isnt a bad thing - beats the alternative Nutritionist's credentials: - [--] years studying food pyramid (designed by grain lobby) - Memorized that fiber is essential (it isn't) - Learned cholesterol is dangerous (it isn't) - Taught saturated fat clogs arteries (it doesn't) - [-----] in student debt - BMI of [--] - Takes Nutritionist's credentials: - [--] years studying food pyramid (designed by grain" [X Link](https://x.com/drterrysimpson/status/2019475361889976381) 2026-02-05T18:17Z 13.7K followers, [----] engagements "Ever wonder why the same gym bro is selling you a peptide to inject one that isn't regulated has no testing - advises you against having ice on an airplane" [X Link](https://x.com/drterrysimpson/status/2019518807736480118) 2026-02-05T21:09Z 13.8K followers, [----] engagements "Jeffrey Epstein has reached into the medical world with prominent doctor @PeterAttiaMD :" [X Link](https://x.com/drterrysimpson/status/2019568872467362211) 2026-02-06T00:28Z 13.7K followers, [----] engagements "You can always tell when someone hasnt read Ancel Keys work. Ancel Keys did not sit on a pristine 22-country dataset and maliciously hide the naughty ones. In [----] most countries simply did not have reliable age-adjusted coronary mortality data. Garbage in garbage out is not censorship its statistics. The graph was hypothesis-generating which Keys explicitly said. Treating it as a randomized global trial is like blaming Darwin for not sequencing DNA. When Jacob Yerushalmy re-analysed the ecological data he didnt make the fat-heart relationship disappear. He showed what every competent" [X Link](https://x.com/drterrysimpson/status/2019781428356276350) 2026-02-06T14:33Z 13.7K followers, [----] engagements "@vincristine @Ancestral_Coach There is none and he clearly has not looked at vaccine trials but has taken the lazy way out by parroting nonsense" [X Link](https://x.com/drterrysimpson/status/2019867788140245051) 2026-02-06T20:16Z 13.7K followers, [--] engagements "The Lancet meta-analysis examined [--] placebo-controlled randomized trials involving [------] participants assessing [--] additional adverse outcomes beyond the well-known effects of statins such as myalgias and diabetes risk effects that were already acknowledged and reported. When dozens of outcomes are tested random variation is inevitable. That is why false discovery rate corrections exist: to prevent ordinary statistical noise from being mislabeled as biological harm. This is not suppression. It is basic epidemiology. The repeated emphasis on almost significant findings is not a scientific" [X Link](https://x.com/drterrysimpson/status/2020159943127757244) 2026-02-07T15:37Z 13.8K followers, 11.4K engagements "This is a straw man wrapped in sarcasm. No serious physician believes disease is a pharmaceutical deficiency. That line exists only to avoid engaging with what medicine actually says. Poor nutrition does affect brain health. So do hypertension diabetes smoking alcohol sleep apnea genetics and aging. Multiple causes can coexist. Adults learn this early. Diet can improve risk factors. It does not cure atherosclerosis Alzheimers pathology Parkinsons disease or genetic hyperlipidemia once established. Claiming otherwise is not rebelliousits biologically illiterate. Also worth noting the source." [X Link](https://x.com/drterrysimpson/status/2020162840620077422) 2026-02-07T15:48Z 13.9K followers, [----] engagements "@dr_jon_l I thought Trump was the daddy" [X Link](https://x.com/drterrysimpson/status/2020162917530755119) 2026-02-07T15:49Z 13.7K followers, [--] engagements "To P. Jeffrey Ungar PhD Your claim collapses at the first factual checkpoint. Ancel Keys did not have a complete valid age-adjusted 22-country coronary mortality dataset in [----]. What existed were heterogeneous national statistics riddled with misclassification missing age structure and incompatible dietary estimates. Excluding garbage is not cherry-picking; its competence. Jacob Yerushalmy did not show the fatheart relationship basically vanished. He showed ecological correlations are unstable a point Keys himself made. Yerushalmy did not disprove lipid causality nor did he propose an" [X Link](https://x.com/drterrysimpson/status/2020163482864492940) 2026-02-07T15:51Z 13.7K followers, [----] engagements "To Bryan Krantz Calling Ancel Keys unethical only works if you quietly assume facts that arent true. Keys was not caught manipulating data. There was no fabricated dataset no altered numbers no hidden files later exposed. What youre describing is methodological disagreement retroactively reframed as moral failure. In the 1950s: Ecological data were incomplete and inconsistent Coronary death certification varied wildly by country Age adjustment was often impossible Dietary intake estimates were crude at best Excluding unreliable data is not misconduct. Its standard practice then and now. If" [X Link](https://x.com/drterrysimpson/status/2020163923438366971) 2026-02-07T15:53Z 13.7K followers, [----] engagements "One crucial correction: if he had actually followed Keys this likely wouldnt have happened.Ancel Keys never promoted a low-fat sugar-heavy ultra-processed diet. His early books describe what we now call a Mediterranean diet: olive oil nuts legumes vegetables whole grains fish modest meat minimal sugar minimal industrial food.That pattern has been repeatedly validated by later research.What harmed people wasnt Keys diet. It was the misinterpretation of it into low-fat dogma and the industrial food industrys response: fat-free sugar-dense ultra-processed junk none of which appears in Keys" [X Link](https://x.com/drterrysimpson/status/2020165109226918047) 2026-02-07T15:57Z 13.7K followers, [----] engagements "Thimerosal is ethylmercury not methylmercury. Its cleared rapidly doesnt bioaccumulate and was removed from routine childhood vaccines over [--] years ago autism rates kept rising anyway. The CDC didnt get busted. Multiple independent studies across countries found no link between thimerosal and neurodevelopmental harm. Repeating look it up isnt evidence. Its what people say when they havent. You dont get to hand-wave away randomized trials pharmacokinetics and population data with vibes and insults. Science doesnt work that way even when yelling feels good. @drterrysimpson @vincristine" [X Link](https://x.com/drterrysimpson/status/2020165508059001270) 2026-02-07T15:59Z 13.7K followers, [----] engagements "Laughing isnt an argument. Insults arent data. And yelling shill is what people do when theyve run out of facts. Ancel Keys didnt hide data. In [----] most countries lacked reliable age-adjusted coronary mortality statistics. Excluding unusable data is statistics not corruption. If the dietheart hypothesis were built on fraud it wouldnt have survived genetics mechanism prospective cohorts and randomized outcome trials. It did repeatedly long after Keys was gone. And heres the part you keep proving: youd actually have to read Keys to know what he said studied or did. You havent. This isnt about" [X Link](https://x.com/drterrysimpson/status/2020166523722363002) 2026-02-07T16:03Z 13.7K followers, [---] engagements "False. Statin trials did not pre-remove people who had side effects. Run-in periods sleaze. Theyre used across RCTs to reduce noise from early non-adherence and improve internal validity before randomization. Key point critics keep missing: Serious statin harms are adjudicated after randomization and analyzed by intention-to-treat. They are not pre-removed. If statin side effects were a major hidden signal youd expect to see it in: blinded placebo-controlled trials genetic randomization (LDL-lowering variants) pharmacoepidemiology across millions of patients We do not. Greenland McShane and" [X Link](https://x.com/drterrysimpson/status/2020167885105291340) 2026-02-07T16:08Z 13.9K followers, 14.3K engagements "Glucose is not a toxin. But everything has a toxic level: oxygen water salt glucose and cholesterol. That fact does not negate benefits - it puts it in perspective and to ignore it is simple ignorance. Cholesterol is not a toxin. Its a structural molecule your body cannot function without. Cholesterol is not a toxin. Its a structural molecule your body cannot function without" [X Link](https://x.com/drterrysimpson/status/2020168678730527104) 2026-02-07T16:12Z 13.9K followers, [----] engagements "Show me you don't understand SV40 promoters without telling me you don't understand them. "The mRNA vaccines are all completely contaminated.the Pfizers are all full of SV40" Dr. Angus Dalgleish Oncologist "SV40 was what in my day we put into mice to make them grow tumors.& we're putting this into humans" "These people behind Pfizer & Moderna are pure evil" https://t.co/r7IXwakpII "The mRNA vaccines are all completely contaminated.the Pfizers are all full of SV40" Dr. Angus Dalgleish Oncologist "SV40 was what in my day we put into mice to make them grow tumors.& we're putting this into" [X Link](https://x.com/drterrysimpson/status/2020168970683453609) 2026-02-07T16:13Z 14.1K followers, [----] engagements "This is a nurse not a doctor - and she is simply wrong. She cannot describe what to do with a patient who cannot get enough oxygen to maintain life - she would not put them on a vent Would she let them die That is the alternative. We did learn a lot about treating covid we made some mistakes but what emptied the hospitals was the vaccine. But do tell how to manage covid without vaccine do tell what they should have done - this isn't a real trained physician who understands physiology this is a nurse who couldn't tell you the basics of pulmonary physiology but claims to know more than the" [X Link](https://x.com/drterrysimpson/status/2020169853836161422) 2026-02-07T16:16Z 13.8K followers, 19.5K engagements "Kind of shows you how well the vaccine works eh Exposing the tetanus hoax - In the last decade [--] died from tetanus in the US. - It's a vaccine that can be taken at the time of injury. Yet babies are given [--] shots. - The risk is that [--] in [---] million will die from tetanus. A Big Pharma scam https://t.co/yU97AQ4H3o Exposing the tetanus hoax - In the last decade [--] died from tetanus in the US. - It's a vaccine that can be taken at the time of injury. Yet babies are given [--] shots. - The risk is that [--] in [---] million will die from tetanus. A Big Pharma scam https://t.co/yU97AQ4H3o" [X Link](https://x.com/drterrysimpson/status/2020171800647463139) 2026-02-07T16:24Z 13.7K followers, [----] engagements "Bedside care is not competence to determine if a patient should be intubated or not. Nor should one assume they have the competence to determine what pharmacologic interventions are needed. Often we were called by the nurses to intubate patients who failed prone positioning and were close to coding. Yes we were given a lot of bad advice like not to use steroids or NSAID - but we did what we do and tested those and found better ways to do things. The anti-vax tropes use our inability to provide definitive care against us to say we killed patients with this novel virus as a mass slaughter - and" [X Link](https://x.com/drterrysimpson/status/2020245818981380429) 2026-02-07T21:18Z 13.7K followers, [---] engagements "@dr_jon_l @drtaubraun Does Santa exist in this fantasy" [X Link](https://x.com/drterrysimpson/status/2020344936214991041) 2026-02-08T03:52Z 13.7K followers, [--] engagements "@dr_jon_l @KenDBerryMD Alas their cult leader is exempt from such rules" [X Link](https://x.com/drterrysimpson/status/2020346033746923970) 2026-02-08T03:56Z 13.7K followers, [--] engagements "Yes this doctor who makes all of his patients see a chiropractor once a week and sells supplements found the secret. He is such a lightweight The real cause of heart disease has been buried for decades in favor of the lie about cholesterol. [--] million Americans take statins to lower their cholesterol thinking its the best way to protect their hearts. But what doctors never tell them is that statins interfere with The real cause of heart disease has been buried for decades in favor of the lie about cholesterol. [--] million Americans take statins to lower their cholesterol thinking its the best" [X Link](https://x.com/drterrysimpson/status/2020346680600907914) 2026-02-08T03:59Z 13.9K followers, [----] engagements "Tell me you have not been to Iceland without telling me Iceland: Fourth highest life expectancy globally (83 years). Traditional Icelandic diet: - Fatty lamb - Fatty fish (salmon herring) - Butter - Skyr (high-protein dairy) - Liver - Blood pudding - Fermented shark - Dried fish Virtually no vegetables for most of the year https://t.co/UuC5pGvFCj Iceland: Fourth highest life expectancy globally (83 years). Traditional Icelandic diet: - Fatty lamb - Fatty fish (salmon herring) - Butter - Skyr (high-protein dairy) - Liver - Blood pudding - Fermented shark - Dried fish Virtually no vegetables" [X Link](https://x.com/drterrysimpson/status/2020346928480014529) 2026-02-08T04:00Z 14.2K followers, 11.5K engagements "I would suggest a carnivore lifestyle is a mental health disorder - orthorexia nervosa 8-10 years ago several of us were observing significant mental health improvements among those adopting low carb/keto/carnivore diets - we were often ridiculed even among many in low carb community Today most in the low carb community concede that this does indeed happen We are 8-10 years ago several of us were observing significant mental health improvements among those adopting low carb/keto/carnivore diets - we were often ridiculed even among many in low carb community Today most in the low carb" [X Link](https://x.com/drterrysimpson/status/2020348491797828088) 2026-02-08T04:06Z 13.9K followers, [----] engagements "@drtaubraun @dr_jon_l Dont show that my son doesnt know I am he" [X Link](https://x.com/drterrysimpson/status/2020349653489971502) 2026-02-08T04:11Z 13.7K followers, [--] engagements "Added sugar in the diet should be kept to a minimum - about [--] grams per day for men and [--] for women is the latest. That is added. Diabetics do quite well with whole grains fruits and vegetables. Everyone is slightly different but total avoidance of fruits whole grains and vegetables is advocated by those who do not read the literature" [X Link](https://x.com/drterrysimpson/status/2020526318706942022) 2026-02-08T15:53Z 13.8K followers, [--] engagements "@BornFree_isms @dr_jon_l @FLSurgeonGen So did he get a license to practice medicine or is he just allowed to apply" [X Link](https://x.com/drterrysimpson/status/2020551157207511088) 2026-02-08T17:31Z 13.7K followers, [--] engagements "No serious scientist says every debate is closed. What we say is that the totality of evidence is sufficient to guide clinical practice. On salt and blood pressure: Mechanistic data Metabolic ward studies Population studies Randomized trials Mendelian randomization Outcome reductions in stroke and heart failure All point in the same direction. Yes individual response varies. Yes sodium sensitivity exists. No that does not make the evidence messy in the way Taubes implies. Calling an issue still debated does not negate decades of convergent evidence. Its how controversy entrepreneurs keep" [X Link](https://x.com/drterrysimpson/status/2020554763524559290) 2026-02-08T17:46Z 13.9K followers, [----] engagements "Its hard to make ethical critiques when you only know half the history. Anti-Coronary Club Voluntary transparent non-randomized. Purpose: diet cholesterol not mortality. It succeeded at exactly what it set out to test. Minnesota Coronary Survey Randomized double-blind feeding trial in hospitals/nursing homes. Result: LDL fell significantly. No short-term mortality signal in an elderly institutionalized population refutation of lipid causality. Key facts critics omit: Ancel Keys was not the PI on MCS Data were published not hidden Short duration + late-life intervention + competing risks" [X Link](https://x.com/drterrysimpson/status/2020555496743481420) 2026-02-08T17:49Z 13.8K followers, [---] engagements "@dr_jon_l I feel sorry for the people of Florida. Maybe ICE will send him away" [X Link](https://x.com/drterrysimpson/status/2020561786697888071) 2026-02-08T18:14Z 13.8K followers, [---] engagements "@KingManninen agree [---] percent" [X Link](https://x.com/drterrysimpson/status/2020564187311915194) 2026-02-08T18:23Z 13.8K followers, [---] engagements "Youre still substituting mechanistic plausibility for clinical sufficiency. No one disputes that food quality can influence: satiety signaling (PYY GLP-1) insulin resistance and lipid markers likelihood of passive overconsumption Those are adjunctive effects not proof of durable obesity remission. What should have settled this debate is GLP-1 trial data. When we pharmacologically amplify satiety slow gastric emptying and reduce food noiseoften without changing food qualitypatients lose 1525% of body weight with durability while treatment continues. That effect size exceeds any diet-quality" [X Link](https://x.com/drterrysimpson/status/2020565643695948277) 2026-02-08T18:29Z 13.9K followers, [----] engagements "@AdrianViti @BroChillerman DASH was a study of that diet with and without salt restriction - showing salt influence in real world eating made a difference- not off topic" [X Link](https://x.com/drterrysimpson/status/2020620216011735237) 2026-02-08T22:06Z 13.8K followers, [--] engagements "@MonardaB Its more dangerous to some - it has an effect. The analogy is alcohol- most dont get liver issues but that doesnt mean its benign" [X Link](https://x.com/drterrysimpson/status/2020771189384458747) 2026-02-09T08:06Z 14K followers, [--] engagements "Obesity is a disease and you can become obese on fat and protein @luckynoelle @drterrysimpson @grok is obesity a disease Or an addiction to sugars Can you get obese on fat and protein @luckynoelle @drterrysimpson @grok is obesity a disease Or an addiction to sugars Can you get obese on fat and protein" [X Link](https://x.com/drterrysimpson/status/2020890544898183455) 2026-02-09T16:00Z 13.9K followers, [----] engagements "The Mediterranean Diet has 13000+ peer-reviewed publications in the last decade alone. Claiming it does not exist simply means you havent read the literature or dont understand how dietary patterns are defined and measured in science. And when people disparage Ancel Keys its usually the same tell. Keys did not invent the Mediterranean diet. He described and studied existing dietary patterns associated with lower cardiovascular mortality. If you've done the research you would know this but the basics of research is becoming familiar by reading the primary material. Clearly you have not." [X Link](https://x.com/drterrysimpson/status/2020891386367914478) 2026-02-09T16:03Z 13.9K followers, [----] engagements "1. Stomach pH misused and misunderstood Yes fasting human stomach pH can approach [--]. That does not make us carnivores. Stomach acid diet category Acid sterilizes food and activates pepsin. It evolved to reduce pathogen risk in omnivores and scavengers not just carnivores. True obligate carnivores (cats) cannot survive without taurine vitamin A arachidonic acid and preformed DHA. Humans synthesize or obtain these from mixed diets including plants. Human gastric pH rises substantially after meals unlike obligate carnivores that maintain extreme acidity. Bottom line: Acid carnivory. It reflects" [X Link](https://x.com/drterrysimpson/status/2020894168328118338) 2026-02-09T16:14Z 13.9K followers, 14.1K engagements "@Do_335_A1_Cuba how do you even use grok" [X Link](https://x.com/drterrysimpson/status/2020897821675982988) 2026-02-09T16:29Z 13.9K followers, [---] engagements "The claim that a meat-only diet put Crohns disease into remission mistakes anecdote for evidence and physiology for wishful thinking. Crohns is a relapsing inflammatory disease with spontaneous remissions regression to the mean medication effects and placebo responsesnone of which magically disappear because someone ate steak for a few months. There is no credible evidence that an all-meat diet induces mucosal healing alters the underlying immune pathology or produces durable remission and plenty of reasons to worry about nutritional deficiencies and long-term harm. Confusing personal" [X Link](https://x.com/drterrysimpson/status/2020898528399388982) 2026-02-09T16:32Z 13.9K followers, [---] engagements "Of all the people they could have used for a Superbowl commercial they had someone who served time in prison for rape. Do better" [X Link](https://x.com/drterrysimpson/status/2020899998851084759) 2026-02-09T16:38Z 13.9K followers, [----] engagements "@SandmanRT I would hypothesize that ultra processed food sets off a cascade and for which some people myself included triggers the path. Woodstock was great by the way - a bit muddy in the end" [X Link](https://x.com/drterrysimpson/status/2020941332144156703) 2026-02-09T19:22Z 13.9K followers, [--] engagements "@HRH_Ted apparently you have not. Again do you have a doctorate Do you know how to use pub med" [X Link](https://x.com/drterrysimpson/status/2020958770055217188) 2026-02-09T20:31Z 13.9K followers, [---] engagements "This is backwards. Yes every cell makes cholesterol. Thats exactly why blood LDL levels arent neededcells synthesize what they require. What matters for arteries is how many ApoB/LDL particles are circulating and entering the vessel wall (thats the causal pathway for ASCVD) not whether cholesterol exists. Higher cholesterol live longer is usually confounding + reverse causation in older/ill populations (frailty inflammation cancer malnutrition can lower cholesterol before diagnosis). Observational longevity claims LDL is protective. Lowering LDL does not raise Alzheimers risk. The best" [X Link](https://x.com/drterrysimpson/status/2020960328599863379) 2026-02-09T20:37Z 13.9K followers, [----] engagements "And yet in the most recent studies the plaque growth of patients on extreme low carb patients was rapid. To take exception with all the people who study this without providing evidence is a dangerous public position. Youre delusional if you think there is an ER full of people on a carnivore diet having heart attacks-I wouldnt be surprised if their rate of MIs are significantly lower than the general population. Youre delusional if you think there is an ER full of people on a carnivore diet having heart attacks-I wouldnt be surprised if their rate of MIs are significantly lower than the" [X Link](https://x.com/drterrysimpson/status/2020960591771467829) 2026-02-09T20:38Z 13.9K followers, 14.6K engagements "My [--] yo dog" [X Link](https://x.com/drterrysimpson/status/2020970921855705489) 2026-02-09T21:19Z 13.9K followers, [----] engagements "agree - and here is from @EvidenceOpen "The primary mechanism of weight loss appears to be appetite suppression and reduced energy intake. Semaglutide reduces caloric intake by approximately 35% compared to placebo while liraglutide reduces it by approximately 16%. Recent mechanistic work shows semaglutide activates specific neurons in the dorsal vagal complex that promote fat utilization and reduce food intake but whether this represents metabolic enhancement beyond calorie reduction remains unclear." I do wish it had more magic I'd like to think it brings Hogwarts and the wand says the" [X Link](https://x.com/drterrysimpson/status/2020982185885667499) 2026-02-09T22:04Z 13.9K followers, [---] engagements "This argument fails because it rewrites the trial after the fact. Both arms received the same counseling. One arm lost 15% the other 2.4%. The difference is the drug. Thats not metabolic magic its pharmacology. Claiming the placebo group could have lost 1520% if only theyd tried harder is not analysisits counterfactual wish-casting. In clinical science we analyze what happened not what Twitter imagines might have happened. If poor compliance explains the result you must explain why compliance systematically improved only when GLP-1 signaling was altered. Appetite suppression gastric emptying" [X Link](https://x.com/drterrysimpson/status/2021040719079800981) 2026-02-10T01:57Z 13.9K followers, 10.8K engagements "@sarasteinmd God it is the boring diet of people who have a boring palate or who havent grown up" [X Link](https://x.com/drterrysimpson/status/2021066934977270015) 2026-02-10T03:41Z 13.9K followers, [---] engagements "The charge is theatrical rather than substantive. Waving Gurven & Kaplan (2007) like a talisman does not convert paleoanthropology into clinical nutrition nor does it absolve one from engaging with outcomes that actually kill people in the modern world. Describing how small-scale societies obtained food under conditions of infection trauma and short life expectancy is not the same as demonstrating reductions in cardiovascular events diabetes or mortality. That distinction is not pedantry; it is the difference between storytelling and medicine. Sneering at TikTok surgeons merely advertises an" [X Link](https://x.com/drterrysimpson/status/2021070650560086331) 2026-02-10T03:56Z 13.9K followers, [--] engagements "When someone substitutes profanity for argument its usually because the argument has gone missing. Calories are a unit of energy measured by metabolic effect not something one gnaws on like a croutona distinction understood by every first-year physiology student. Screaming about first principles while misunderstanding them is not rigor; its performance art for the incurious. If abuse were evidence youd have won a Nobel by now. For fuck's sake dry up and blow away you fucking imbecile. It is a physical IMPOSSIBILITY to eat calories. This CANNOT be done you utter moron. Learn some basic first" [X Link](https://x.com/drterrysimpson/status/2021072560033759724) 2026-02-10T04:03Z 13.9K followers, [----] engagements "Or eat reasonably and join the majority that lose fat If You're Thinking of Taking a GLP-1 Read This: Research shows up to 40% of the weight you lose on Ozempic isn't fat. It's muscle. And once it's gone your metabolism pays the price. We built the The High Performance GLP-1 Protocol to fix this. It protects your muscle https://t.co/rYNs7IYsno If You're Thinking of Taking a GLP-1 Read This: Research shows up to 40% of the weight you lose on Ozempic isn't fat. It's muscle. And once it's gone your metabolism pays the price. We built the The High Performance GLP-1 Protocol to fix this. It" [X Link](https://x.com/drterrysimpson/status/2021074483361219011) 2026-02-10T04:11Z 13.9K followers, [----] engagements "What youve done is stack anecdotes selective endpoints and evolutionary romance and then declared victory over medicine. Gurven & Kaplan did not show that hunter-gatherers were thriving into their 70s as a norm; they showed conditional survival after childhood in populations dominated by trauma infection and energy scarcityhardly a model for modern chronic disease prevention. Longevity without antibiotics statins anesthesia or blood pressure control is not proof of dietary supremacy; its proof of survivorship bias. Your keto claims fare no better. A 24% mortality drop without context" [X Link](https://x.com/drterrysimpson/status/2021076446454956456) 2026-02-10T04:19Z 13.9K followers, [--] engagements "The appendix proves nothing of the sort. Humans do not lack a cecum; we have a reduced one and the appendix is not a vestigial shrug but an immune organ rich in lymphoid tissue involved in gut immunity and microbiome regulation. We are not obligate hindgut fermenters like horses or rabbitsno one claims we arebut we do ferment fiber via colonic bacteria producing short-chain fatty acids with measurable metabolic effects. That process is smaller in scale not absent. To leap from humans dont have a cows fermentation chamber to therefore meat is our primary food is anatomical illiteracy. By that" [X Link](https://x.com/drterrysimpson/status/2021076983237706062) 2026-02-10T04:21Z 14.1K followers, [----] engagements "@Papaghostbear Ask any red state that lives in permanent need of places like California to subsidize them through federal taxes" [X Link](https://x.com/drterrysimpson/status/2021237710866804812) 2026-02-10T14:59Z 13.9K followers, [----] engagements "@idrone22 yes like Alabama" [X Link](https://x.com/drterrysimpson/status/2021244693690908684) 2026-02-10T15:27Z 13.9K followers, [----] engagements "This is a standard RCT not a vibes-based wellness retreat. Adherence wasnt assumedit was handled the same way it is in virtually every long-term obesity trial. Both arms received identical lifestyle counseling Energy intake was assessed with validated dietary questionnaires (the same tools used across obesity RCTs) Weight change itself is the objective adherence signalif the placebo group were actually sustaining a [---] kcal/day deficit for [--] weeks you would not see 2.4% loss More importantly: If the explanation were poor compliance youd expect wide variance and some large losers in placebo." [X Link](https://x.com/drterrysimpson/status/2021253539759308831) 2026-02-10T16:02Z 13.9K followers, [----] engagements "Confidence is not a surrogate for evidence. Peter Attia cites literature fluently but citation without synthesis is not expertise. He did not complete residency operates outside clinical consensus and his emphasis on VO max high-protein absolutism and rapamycin exceeds human evidence. In another era this was goat-gland medicinetoday its the same grift just better ring lights and newer tattoos. https://twitter.com/i/web/status/2021273572757676416 https://twitter.com/i/web/status/2021273572757676416" [X Link](https://x.com/drterrysimpson/status/2021273572757676416) 2026-02-10T17:22Z 14.1K followers, [----] engagements "This is a confident monologue built on a false premise: that feeling bad on a diet is proof one simply failed to eat enough of its most extreme component. Rabbit starvation is a real historical phenomenon but invoking it here is a bait-and-switch. Humans do not spontaneously develop protein poisoning because they ate chicken and coffee; they feel unwell because extreme single-macronutrient diets are metabolically narrow socially fragile and biologically unnecessary. The claim that humans need [---] grams of fat a day is not physiology its ideology. There is no requirement in human biology for" [X Link](https://x.com/drterrysimpson/status/2021326911239225561) 2026-02-10T20:54Z 13.9K followers, [----] engagements "@wearecharlie8 Oh its not a dollar for dollar exchange they are quite subsidized by states like California New York and Illinois" [X Link](https://x.com/drterrysimpson/status/2021341609384870133) 2026-02-10T21:52Z 13.9K followers, [---] engagements "Apparently fat-shaming is still in style. Unless of course they come to your course/workout/gym/whatever. God forbid they should get a prescription for a disease which has more efficacy Ozempic is the fastest-growing drug in America. We don't have a healthcare crisis. We have a personal responsibility crisis dressed up as a medical condition. Ozempic is the fastest-growing drug in America. We don't have a healthcare crisis. We have a personal responsibility crisis dressed up as a medical condition" [X Link](https://x.com/drterrysimpson/status/2021342663136641548) 2026-02-10T21:57Z 14K followers, 15.6K engagements "This is what happens when arithmetic is performed without scale category or comprehension. Quoting a few million in taxes versus benefits without specifying who which taxes which benefits or relative to what base is not analysisit is numerology with a political accent. California does not contribute five million dollars in taxes. It contributes hundreds of billions annually in federal revenueincome taxes payroll taxes corporate taxes excise taxesfar more than it receives back in federal spending. The figures you cite are almost certainly a single program slice or a cherry-picked transfer" [X Link](https://x.com/drterrysimpson/status/2021359834696908872) 2026-02-10T23:05Z 13.9K followers, [---] engagements "People leave California because housing is scarce and expensivenot because Alabama suddenly became the economic engine of the United States. Cheap land isnt productivity migration isnt subsidy and square footage is not a balance sheet. And its still Alabama @drterrysimpson @DarkagePossum @idrone22 People are flooding from California to Huntsville. COL is obscenely high. You can get a [--] bedroom mansion in Huntsville for the price of an average home in California. @drterrysimpson @DarkagePossum @idrone22 People are flooding from California to Huntsville. COL is obscenely high. You can get a 10" [X Link](https://x.com/drterrysimpson/status/2021360317452935528) 2026-02-10T23:07Z 13.9K followers, [----] engagements "@dr_jon_l @thereal_truther @CombatingAutism @AgeofAutism Some are pdf filed in their moms basement" [X Link](https://x.com/drterrysimpson/status/2021385444550930512) 2026-02-11T00:47Z 13.9K followers, [--] engagements "Yes they extend to atherosclerosis Low carb diet benefits are beyond weight loss and Diabetes. Low carb diet benefits are beyond weight loss and Diabetes" [X Link](https://x.com/drterrysimpson/status/2021385654010360074) 2026-02-11T00:47Z 13.9K followers, [----] engagements "@wearecharlie8 @AdonicaSS California state is not in debt - you are mixing in local pension debt - that is up to the cities - and is an accounting issue not a typical debt" [X Link](https://x.com/drterrysimpson/status/2021398826469490860) 2026-02-11T01:40Z 13.9K followers, [--] engagements "One of the hardest things to see is my dog as he cannot control his back legs. He is deaf blind and loves every minute with us. Walking is his favorite thing in the world. Instead of going away this weekend I am staying with him. He is on borrowed time so I am going to try to sneak some more time in with him" [X Link](https://x.com/drterrysimpson/status/2021401352401047797) 2026-02-11T01:50Z 14.2K followers, [----] engagements "You have forgotten these things were discussed. LDL receptor status is quite important in therapies but Among other differences I noted that veins likely express fewer LDL receptors but receptor density is not the decisive issue. The arterialvenous difference in atherosclerosis is multifactorial. Arteries operate under higher pressure experience disturbed and oscillatory shear stress have a thicker intima greater smooth muscle cell content and a different extracellular matrix composition particularly proteoglycans that retain apoB particles. LDL entry occurs largely via transcytosis and" [X Link](https://x.com/drterrysimpson/status/2021408379336524019) 2026-02-11T02:18Z 13.9K followers, [---] engagements "@VickieMacFadden They have sold dogma - instead of being helpful. They should focus on working with science but alas" [X Link](https://x.com/drterrysimpson/status/2021409382052004258) 2026-02-11T02:22Z 13.9K followers, [---] engagements "@DrRogerHugh Do show your data if you have some to the contrary but two things have great efficacy for weight loss: surgery and now GLP-1. Exercise is a great adjunct but that is it" [X Link](https://x.com/drterrysimpson/status/2021410740574487016) 2026-02-11T02:27Z 14.2K followers, [---] engagements "@VoidMillennia @HRH_Ted You find his diatribe funny You think his abuse is funny You think he is bright because he says he is and yet doesnt know the basis of causation in medicine And you think that I support and take GLP-1 that this is a bad thing" [X Link](https://x.com/drterrysimpson/status/2021411660074975368) 2026-02-11T02:31Z 13.9K followers, [--] engagements "@VoidMillennia @HRH_Ted Given the abuse Ive received here I see no reason to engage in another conversation. And that you find his abuse amusing is something you should reflect upon. I shall save you some trouble and block you so you dont have to be troubled with modern science" [X Link](https://x.com/drterrysimpson/status/2021416310421574118) 2026-02-11T02:49Z 13.9K followers, [--] engagements "@Chaddadbod Blood test - a common one too" [X Link](https://x.com/drterrysimpson/status/2021427426103075123) 2026-02-11T03:33Z 13.9K followers, [--] engagements "Youre mixing valid philosophy-of-science points with a conclusion that doesnt follow from the evidence we actually have. 1) Correlation can never prove causation (including smoking and cancer). Correlation alone doesnt prove causation. Correct. But medicine doesnt use correlation alone. We use triangulation: temporality + doseresponse + consistency + biological mechanism + reversibility + experiments + genetics. Smoking lung cancer is one of the classic examples where multiple independent lines converge. 2) Burden of proof is on you: LDL causes atherosclerosis. Agreedand that burden has been" [X Link](https://x.com/drterrysimpson/status/2021602697187897767) 2026-02-11T15:10Z 14.2K followers, [----] engagements "It is always nice when you see bits of improvement in your dog. Today he walked up the stairs without assistance and pain notice the new appliance where I can assist him with less back strain. He is quite proud of himself" [X Link](https://x.com/drterrysimpson/status/2021628696176865420) 2026-02-11T16:53Z 13.9K followers, [----] engagements "Since there is no advantage to raw milk other than infectious disease drinking it has all the advantages of hoping the water in the toilet was flushed before you partake of it. When it comes to raw milk two things will most certainly happen lying with statistics and fear mongering the dangers https://t.co/UQBnjae2QI When it comes to raw milk two things will most certainly happen lying with statistics and fear mongering the dangers https://t.co/UQBnjae2QI" [X Link](https://x.com/drterrysimpson/status/2021629986982309953) 2026-02-11T16:58Z 14.1K followers, [----] engagements "Of course vitamin K2 regulates calcium. So do your kidneys. So does parathyroid hormone. So does vitamin D. Regulates calcium is the biochemical equivalent of saying a thermostat controls temperature. It tells you nothing about whether the house is on fire. The claim here is not modest. It is not that K2 participates in gamma-carboxylation of matrix Gla protein. That part is textbook. The claim is that K2 reverses existing vascular calcification and restores elasticity to vessels. That is not a mechanistic statement. That is a clinical one. And where are the randomized trials showing" [X Link](https://x.com/drterrysimpson/status/2021635322199912541) 2026-02-11T17:19Z 14K followers, [----] engagements "@CoachBigBri Glad you lost - however that does not activate GLP-1 and GLP-1 lasts a few minutes then is gone. Synthetic GLP-1 goes through different pathways and lasts days" [X Link](https://x.com/drterrysimpson/status/2021666602752827415) 2026-02-11T19:24Z 13.9K followers, [---] engagements "@underdog1030 The combination works because it: Targets two distinct physiologic pathways Prevents metabolic compensation Maximizes LDL receptor upregulation Achieves lower ApoB particle burden Mechanistically elegant. Clinically validated" [X Link](https://x.com/drterrysimpson/status/2021959991406780678) 2026-02-12T14:50Z 14.2K followers, [--] engagements "@deborahbrian @DevinThorn33342 I dont know or care how people tell the difference in LLM or personal . Its the content not the prose. I use @EvidenceOpen for studies but not for their writing - which is clinical and not narrative" [X Link](https://x.com/drterrysimpson/status/2021990393873924374) 2026-02-12T16:50Z 13.9K followers, [--] engagements "GLP-1s take away vision is misinformation. ADA notes early retinopathy worsening can occur when A1c drops fasta known rapid control effect not proof of drug toxicity. RCT meta-analysis shows no significant increase in vision-threatening events; NAION signals are rare and still being clarified. Monitor eyes dont panic. https://twitter.com/i/web/status/2022001849335975969 https://twitter.com/i/web/status/2022001849335975969" [X Link](https://x.com/drterrysimpson/status/2022001849335975969) 2026-02-12T17:36Z 14.2K followers, [----] engagements "@MalleyGlass Love olive oil - and I don't do many artificial sweeteners because they taste too sweet to me -but looks like damage from them happens at huge doses" [X Link](https://x.com/drterrysimpson/status/2022445463392473421) 2026-02-13T22:59Z 14.2K followers, [--] engagements "GLP-1 drugs have long term success from studies. If you want weight loss - see someone who is actually board certified in obesity medicine - not a diet guru The harsh truth about long-term success on weight loss drugs. If you're looking for real guidance to improve your health long-term be sure to check out @reverohealth today. https://t.co/EE2aqkwwO2 The harsh truth about long-term success on weight loss drugs. If you're looking for real guidance to improve your health long-term be sure to check out @reverohealth today. https://t.co/EE2aqkwwO2" [X Link](https://x.com/drterrysimpson/status/2021638117120520295) 2026-02-11T17:31Z 14.2K followers, [----] engagements "The COVID response exposed failures of institutions not failures of science. That distinction matters. Science did what science does: it updated as evidence changed. Masks transmission dynamics boosters myocarditis riskthose corrections are a feature not a bug. What eroded trust was poor communication political overreach and officials speaking with unwarranted certaintynot some mythical Vaccine Industrial Complex. Layered on top of that was a well-funded coordinated anti-vaccine ecosystem that exploited every misstep. The same network that denied COVIDs existence pivoted seamlessly to" [X Link](https://x.com/drterrysimpson/status/2016992375382692076) 2026-01-29T21:50Z 14.2K followers, 13.3K engagements "Real food is adding tallow to french fries - to having your Superbowl spokesman be a convicted rapist who shames people who are obese This movement will not slow down. We are changing the incentives. We are restoring common sense. We are putting REAL FOOD back at the center of the American diet. Together we will Make America Healthy Again. This movement will not slow down. We are changing the incentives. We are restoring common sense. We are putting REAL FOOD back at the center of the American diet. Together we will Make America Healthy Again" [X Link](https://x.com/drterrysimpson/status/2022365522898366479) 2026-02-13T17:41Z 14.2K followers, [----] engagements "The claim that the chickenpox vaccine caused shingles epidemics is a resurrection of an old immune-boosting hypothesis that was modeled debated and then tested against decades of real-world data. Shingles rates were rising before vaccination have risen in countries without universal varicella programs and track far more cleanly with aging populations than with pediatric immunization schedules. Meanwhile childhood hospitalizations and deaths from varicella collapsed after vaccination. That is not a trade of one plague for another; it is disease prevention working exactly as intended. RFK JR -" [X Link](https://x.com/drterrysimpson/status/2022418042786066678) 2026-02-13T21:10Z 14.2K followers, 14.3K engagements "Obesity is not a moral parable about proper order or evil humors; it is a chronic relapsing biologically mediated disease characterized by dysregulated energy balance neurohormonal signaling and adipose tissue dysfunction. Yes lifestyle interventions can dramatically improve metabolic health and I prescribe them daily but the fact that behavior influences a disease does not make it optional or philosophical. Hypertension improves with sodium restriction; type [--] diabetes improves with weight loss; coronary disease improves with exercise yet none cease to be diseases. The danger in framing" [X Link](https://x.com/drterrysimpson/status/2022420854391607551) 2026-02-13T21:21Z 14.2K followers, [----] engagements "Statins save lives and every drug from antibiotics to statins are studied - so be contrarian but be honest Crestor and all statins are cellular poisons that block the crucial mevalonate pathway. Harms greatly exceed the minuscule or imaginary benefit. @Marion436842126 Crestor and all statins are cellular poisons that block the crucial mevalonate pathway. Harms greatly exceed the minuscule or imaginary benefit. @Marion436842126" [X Link](https://x.com/drterrysimpson/status/2022488426361278736) 2026-02-14T01:49Z 14.2K followers, [----] engagements "Yes ivermectin nonsense is sweeping the globe with anecdotes that make Paul Bunyan seem like a midget IVERMECTIN CANCER Revolution is sweeping the Globe 😃 Ivermectin Fenbendazole Mebendazole are the future of Cancer Care. Nothing else comes remotely close to the potential for helping millions of cancer patients 😉 IVERMECTIN CANCER Revolution is sweeping the Globe 😃 Ivermectin Fenbendazole Mebendazole are the future of Cancer Care. Nothing else comes remotely close to the potential for helping millions of cancer patients 😉" [X Link](https://x.com/drterrysimpson/status/2022488668225917222) 2026-02-14T01:50Z 14.2K followers, [----] engagements "During the major COVID waves hospitals across the country canceled elective surgeries delayed cancer operations postponed joint replacements deferred cardiac procedures because beds ventilators and staff were consumed by COVID admissions. I lived that. Many of us did. ICUs were full. Recovery rooms became ICU overflow. Surgical wards became COVID units. Now ask the obvious question: What emptied those hospitals Not wishful thinking. Not podcasts. Not revisionist IFR math. Vaccination. After widespread vaccination severe cases and ICU admissions dropped dramatically relative to prior waves" [X Link](https://x.com/drterrysimpson/status/2022703312852967867) 2026-02-14T16:03Z 14.2K followers, 42.5K engagements "Sorry - you may think it is a lie but it is not and administrators cannot empty a hospital that is a doctor who can discharge a patient. And since I was there and you were not- you are just a conspiracy nut spreading nonsense @drterrysimpson This is a lie. The hospitals were emptied because administrators emptied them because they were told to. They were not full of COVID admissions at all. In Australia COVID cases went up 100x AFTER the vaccine rollout from [------] to [--------]. Deaths went up 20x https://t.co/THpehuXRtI @drterrysimpson This is a lie. The hospitals were emptied because" [X Link](https://x.com/drterrysimpson/status/2022805224398950747) 2026-02-14T22:48Z 14.2K followers, [----] engagements "Mikes claim sounds tidy but its wrong. If eating the same number of calories were all Ozempic did the STEP trials wouldnt exist. Heres what the data actually show: Semaglutide causes more weight loss than calorie restriction alone. In STEP [--] both groups were prescribed a reduced-calorie diet and physical activity. Semaglutide: 14.9% body weight Placebo (same calorie advice): 2.4% That 12.5% difference is the drug effect not willpower. Pair-feeding studies settle this directly. When animals on semaglutide are fed the same number of calories as controls they still lose more weight and more fat" [X Link](https://x.com/drterrysimpson/status/2020969974152691843) 2026-02-09T21:16Z 14.2K followers, 208.3K engagements "The ketogenic diet was not suppressed. It fell out of favor because anti-epileptic drugs were easier to administer and worked for many patients without the dietary burden. And importantly: keto is still recommended particularly for refractory pediatric epilepsy. Centers like Mayo Clinic and Johns Hopkins Medicine actively run ketogenic programs today. But no side effects is simply incorrect. Ketogenic therapy can cause kidney stones micronutrient deficiencies constipation dyslipidemia slowed growth in children and requires close monitoring. Thats why its medically supervised. This isnt meat" [X Link](https://x.com/drterrysimpson/status/2022372880076722611) 2026-02-13T18:10Z 14.2K followers, 21.5K engagements "Tell me you don't understand biochemistry without telling me. @LauraLoomer @KassyAkiva Do you know the long term implications of facial filler which migrates and does not dissolve And Botox which paralyzes essential musculature for years Do you wonder where that Botox might go- say- into your lymph nodes @LauraLoomer @KassyAkiva Do you know the long term implications of facial filler which migrates and does not dissolve And Botox which paralyzes essential musculature for years Do you wonder where that Botox might go- say- into your lymph nodes" [X Link](https://x.com/drterrysimpson/status/2022419986640441536) 2026-02-13T21:17Z 14.2K followers, [----] engagements "Oh stop playing with statistics. That claim flips risk reduction on its head. Heres the reality: Most people statin or not will not have a heart attack in the next [---] years. Thats how population risk works. The question isnt Would everyone have had an MI without a statin The question is: Does lowering LDL with statins reduce events compared with not lowering it Yes. Repeatedly. In primary and secondary prevention. What the trials actually show In high-risk patients statins reduce major cardiovascular events by 2030% per mmol/L LDL reduction. In secondary prevention (people who already had an" [X Link](https://x.com/drterrysimpson/status/2022497729763754259) 2026-02-14T02:26Z 14.2K followers, [----] engagements "This is recycled mythology dressed up as revelation. First: polio did not disappear when DDT spraying declined. DDT use in the U.S. peaked in the 1950s. Paralytic polio epidemics peaked in [----]. What followed the sharp sustained collapse in polio cases was the introduction of the inactivated polio vaccine in [----] and the oral vaccine in the early 1960s. Correlation is not causation especially when the timeline is wrong. Second: yes 9599% of poliovirus infections are asymptomatic. That has been known for decades. Its in every epidemiology textbook. That fact doesnt weaken the vaccine argument" [X Link](https://x.com/drterrysimpson/status/2022692344135586155) 2026-02-14T15:20Z 14.2K followers, 10.6K engagements "The Federal government has granted South Carolina [---] million to assist in the measles outbreak. But what if those people would have been vaccinated instead: MMR vaccine cost (public sector pricing): Vaccine itself: $20$25 per dose Two doses required: $40$50 Add administration costs (nursing supplies logistics): $20$30 per dose So a fully vaccinated person costs roughly $70$100 total. If [---] people had been fully vaccinated: Low estimate: [---] $70 = $63000 High estimate: [---] $100 = $90000 The federal measles response funding: $1.4 million Even at the high estimate vaccinating those [---] people" [X Link](https://x.com/drterrysimpson/status/2022697144910778569) 2026-02-14T15:39Z 14.2K followers, [----] engagements "Incorrect. Food quality does not allow someone to lose weight. It is a nice story and we advocate for healthy foods like the Mediterranean diet - but that is not how one can lose weight. Yes UPF is easier to increase calories but obesity is not food choice or willpower it is a disease The secret to fat loss Food quality counting calories https://t.co/8oYisnicX4 The secret to fat loss Food quality counting calories https://t.co/8oYisnicX4" [X Link](https://x.com/drterrysimpson/status/2020533297760309469) 2026-02-08T16:20Z 14.2K followers, 12.7K engagements "It is clear that GLP-1 are a danger to the health and life coaches and diet demagogues. They work quite well - but the amount of resistance from people who want to defend their turf is extraordinary" [X Link](https://x.com/drterrysimpson/status/2021261788717674888) 2026-02-10T16:35Z 14.2K followers, 40.4K engagements "What happened in that debate was not science. It was rhetorical theater. He redefined causation to mean deterministic laboratory proof in humans a standard that cannot be met for any chronic disease. Not hypertension. Not diabetes. Not smoking. Not heart disease. Having set an impossible bar he then declared victory when it wasnt met. He redefined risk as metaphysical certainty. He dismissed adjusted epidemiology as fabrication. He called convergent evidence theology. He rejected Mendelian randomization because it wasnt perfect. This is not skepticism. It is definitional sabotage. Medicine" [X Link](https://x.com/drterrysimpson/status/2021977449974968535) 2026-02-12T15:59Z 14.2K followers, [----] engagements "@CoachBigBri Some cannot and if we just have whole food we will not be able to have enough or store enough to feed the planet not even enough to feed the US" [X Link](https://x.com/drterrysimpson/status/2022363246192468334) 2026-02-13T17:32Z 14.2K followers, [---] engagements "Yes we can call you anti-vax - and rather silly for not knowing the difference between ethyl mercury and methyl mercury - well you do but that does not fit the narrative -- your antivax narrative RFK Jr.: I spent [--] years trying to get mercury out of the fish in this country and nobody ever called me anti-fish." https://t.co/Of9PziJ2rx RFK Jr.: I spent [--] years trying to get mercury out of the fish in this country and nobody ever called me anti-fish." https://t.co/Of9PziJ2rx" [X Link](https://x.com/drterrysimpson/status/2022365781145870795) 2026-02-13T17:42Z 14.2K followers, 15K engagements "If you have a loved one in the hospital let them rest - dont stay more then ten or twenty minutes - I was in the ICU for five days - trust me youre keeping them up and youre not helping the staff do their job Genuine bit of advice: If you have a close relative over the age of [--] in the hospital and you love them DO NOT leave them alone. Be there every moment that you are allowed to be there watching over things as a solid advocate. Genuine bit of advice: If you have a close relative over the age of [--] in the hospital and you love them DO NOT leave them alone. Be there every moment that you" [X Link](https://x.com/drterrysimpson/status/2022489256854478889) 2026-02-14T01:53Z 14.2K followers, 11.4K engagements "He invokes leucine like a priest invoking Latin mystical threshold sacred number metabolic incantation and just as the congregation begins to worry their breakfast is heresy behold: salvation arrives in the form of his own powdered sacrament. It is remarkable how often the crisis in modern physiology can be resolved by entering ones credit card number. Nothing is a "high protein" meal if it does not eclipse the leucine threshold for muscle protein synthesis 2.5g. You would need [--] eggs to achieve this 4.5oz of steak chicken or fish 30g of whey protein [--] cups greek yogurt and far more plant" [X Link](https://x.com/drterrysimpson/status/2022498496402829634) 2026-02-14T02:29Z 14.2K followers, [----] engagements "Chanting saturated fat is healthy four times does not transmute a review article into a randomized trial demonstrating benefit. The cited paper argues there is no clear association in selected data. It does not show improved outcomes. It does not overturn LDL biology. It does not invalidate decades of mechanistic genetic epidemiologic and interventional evidence. And even within the observational literature saturated fat from dairy does not behave the same as saturated fat from processed meat so slogans are already scientifically illiterate. Not conclusively harmful is not the same thing as" [X Link](https://x.com/drterrysimpson/status/2022781837437972962) 2026-02-14T21:15Z 14.2K followers, [----] engagements "@KerryOLeary4 Not at all - I was there - and so were my colleagues" [X Link](https://x.com/drterrysimpson/status/2022820461357469942) 2026-02-14T23:49Z 14.2K followers, [---] engagements "Lowering drug prices is good policy. Period. But lets be precise. The Most Favored Nation (MFN) rule was proposed near the end of the Trump administration to tie certain Medicare drug prices to prices paid in other countries. It faced legal challenges and was never fully implemented before being rescinded. Ozempics list price in the U.S. did not universally drop from $1200 to $400 because of MFN. Price reductions and discounts were seeing now are largely the result of manufacturer adjustments negotiations with PBMs insurance coverage expansion and competitive pressure in the GLP-1 market. If" [X Link](https://x.com/drterrysimpson/status/2022840107452211439) 2026-02-15T01:07Z 14.2K followers, [---] engagements "That screenshot shows a manufacturer savings program not a federal price control. The $199 starter dose price is a coupon-based promotional offer through Novo Nordisk not a permanent list price reduction and not proof of a tariff-induced structural change. These programs are common in the U.S. pharmaceutical market and are typically limited to: Certain doses Certain insurance statuses A defined time period The list price remains around $1000+. The savings is the manufacturer absorbing part of the cost temporarily to expand market share and compete in a rapidly growing GLP-1 space. The Most" [X Link](https://x.com/drterrysimpson/status/2022845169641623832) 2026-02-15T01:27Z 14.2K followers, [---] engagements Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing
@drterrysimpson Dr Terry SimpsonDr Terry Simpson posts on X about dr, in the, food, if you the most. They currently have [------] followers and [---] posts still getting attention that total [-------] engagements in the last [--] hours.
Social category influence finance 7.69% countries #957 celebrities 1.28% stocks 1.28%
Social topic influence dr #23, in the #288, food #5628, if you #4337, carnivore #239, science 5.77%, health #3126, data #8, countries #13, the most 3.85%
Top accounts mentioned or mentioned by @anonemus349832 @new_york_steak @skunk_bucketss @souaprotector @diy_tardis @drjonl @albowers11 @qwixxf @voidmillennia @curiousthrifty @limitededish970 @sandmanrt @sgonzalez37054 @suzannereads @lookingatyoum8 @ralphsmorra @vincristine @pjungar @grok @hrhted
Top assets mentioned Costco Wholesale Corporation (COST)
Top posts by engagements in the last [--] hours
"There are many reasons young people get colon cancer including getting antibiotics as a child genetic issues and even if you have done everything right you can get colon cancer. It isn't about a food fight - it is about early screening and if you feel something is off - unexplained iron deficiency anemia blood in the stool or unexplained weight loss - it is time to get a colonoscopy Beautiful Actor James Van der Beek ate lots of fruits and vegetables lots of smoothies. Then he got colon cancer. Its so sad so senseless. Maybe humans are not supposed to eat so many plants so many superfoods so"
X Link 2026-02-12T23:28Z 14.2K followers, [----] engagements
"The idea that a carnivore diet prevents autoimmune disease is a claim in search of evidence. Autoimmune diseases are heterogeneous genetically influenced immune-mediated conditions with complex environmental triggers. There are no randomized controlled trials showing that a meat-only diet prevents the onset of Crohns lupus rheumatoid arthritis multiple sclerosis or any other autoimmune disease. None. Elimination diets can reduce symptoms in selected patientsbecause removing certain triggers may reduce immune activationbut symptom modulation is not prevention and short-term improvement is not"
X Link 2026-02-12T23:32Z 14.2K followers, [----] engagements
"Were being told hospitals are flooded with GLP-1 complications and that were at the tip of the iceberg. Ive been a bariatric surgeon long enough to remember these drugs when they were still in trials. Ive prescribed them. Ive monitored patients on them. And when the ER had a question about one of my patients on a GLP-1 they called me. I am not seeing a flood. What I see every single shift are the consequences of untreated obesity: heart failure uncontrolled diabetes infections sleep apnea crises fatty liver disease progressing quietly toward cirrhosis. That is the deluge. Yes GLP-1"
X Link 2026-02-13T21:03Z 14.2K followers, 1.1M engagements
"Puerto Ricans are U.S. citizens not guests not freeloaders not an anecdote. Roughly 40% receive federal food assistanceabout the same order of magnitude as the poorest counties in Mississippi Alabama and Louisiana. Poverty is not a foreign policy problem; its an American one. Sneering at the island while ignoring the Deep South is prejudice with a spreadsheet allergy. Fun fact about Puerto Rico: half the island is on a food stamp program paid for by US citizens Fun fact about Puerto Rico: half the island is on a food stamp program paid for by US citizens"
X Link 2026-02-10T04:06Z 14.2K followers, 97.7K engagements
"I can find two publications with your name on them. I can find no evidence of a doctorate no formal training in medicine and no clinical responsibility for patients. Yet you position yourself as an authority on how causation is determined in medicine. What you demonstrated in that debate was not methodological rigor. It was rhetorical absolutism redefining terms until no evidence could ever qualify. That is not how causation is determined in clinical science. It is how arguments are insulated from falsification. You may declare victory. Ill continue practicing medicine under standards"
X Link 2026-02-12T23:26Z 14.2K followers, [----] engagements
"Obesity is a chronic disease. Like hypertension or diabetes when you stop treatment you should anticipate its return. This isnt failure. Its biology. The benefits of weight loss medications may be shorter-lived than originally hoped. Those who stop taking GLP-1s may return to pre-treatment levels of body weight and heart disease risk within two years. https://t.co/NFy9tr2o8i https://t.co/FTqblEEA2p The benefits of weight loss medications may be shorter-lived than originally hoped. Those who stop taking GLP-1s may return to pre-treatment levels of body weight and heart disease risk within two"
X Link 2026-02-12T23:36Z 14.2K followers, 17K engagements
"GLP-1s arent marketed as a cure for obesity and obesity isnt a condition we cure in the first place. Obesity is a chronic relapsing metabolic disease much like hypertension or asthma. When treatment stops the biology returns. Thats not failure thats physiology. Comparing GLP-1s to a crutch misses the mechanism. These medications act on hypothalamic appetite regulation gastric emptying insulin signaling and reward pathways. They address the underlying neurohormonal drivers of weight regain the very forces that make long-term weight loss so difficult. Lifestyle remains foundational. Nutrition"
X Link 2026-02-13T17:48Z 14.2K followers, 21.1K engagements
"Why are younger people getting colon cancer https://open.substack.com/pub/tsimpson/p/why-are-younger-people-getting-colonr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true https://open.substack.com/pub/tsimpson/p/why-are-younger-people-getting-colonr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true"
X Link 2026-02-13T22:55Z 14.2K followers, [----] engagements
"As a bariatric surgeon Ive seen what untreated obesity does diabetes heart disease sleep apnea joint destruction. GLP-1 medications are tools that treat the neurohormonal drivers of appetite. If you withdraw therapy weight often returns because chronic diseases relapse without ongoing management. Thats medicine. Not literature"
X Link 2026-02-13T23:44Z 14.2K followers, 19.8K engagements
"GLP-1 medications have given people something they have not had in decades: hope grounded in biology. For the first time patients feel hunger quiet. Food noise softens. The constant metabolic push to regain weight eases. That is not cosmetic that is neuroendocrinology working the way it should. Hope matters. And it is real. But to claim obesity is not a chronic disease is to ignore the very biology that makes GLP-1s effective. When weight is lost the body does not applaud. Ghrelin rises. Leptin falls. Energy expenditure drops. Appetite circuits amplify. That adaptive response persistent"
X Link 2026-02-14T14:58Z 14.2K followers, 12.4K engagements
"I dont believe prescription medications should be marketed direct-to-consumer. Full stop. If a company can afford a Super Bowl commercial it can afford to lower the price of the drug. We are absolutely being gouged and the ad budget is part of that. Redirect that money to patients instead of prime time. Even telehealth companies like Ro which dont manufacture the drugs but sometimes rely on compounded versions exist in the vacuum created by cost and access barriers. I strongly dislike compounded GLP-1s. Theyre not FDA-approved formulations. But I understand why patients chase them when the"
X Link 2026-02-14T15:07Z 14.2K followers, [----] engagements
"Ah another denier - COVID causes long covid and mRNA is not gene therapy perhaps you should learn some basic biology. MRNA does not integrate into your DNA unless you have reverse transcriptase that some viruses use - like HIV. The mRNA does cause a manufacture of proteins for a brief period of time then it is degraded by the cell. That you can see immune proteins against those proteins doesnt mean they are still there it means the immune system is doing its job. - that is your 6th grade biology lesson for the day There is no long COVID. There is only that you were injected with an"
X Link 2026-02-14T15:51Z 14.2K followers, [----] engagements
"Weight regain after stopping a GLP-1 isnt a failure but to be clear: Yes behavior matters. Yes environment matters. Yes psychological drivers matter. But obesity does not begin as a purely moral or lifestyle defect and then later become metabolic. From the earliest stages of weight gain neurohormonal adaptation begins. Leptin signaling shifts. Ghrelin dynamics change. Energy expenditure subtly declines. Reward circuitry adapts. The body starts defending the higher weight. Thats biology not weakness. GLP-1 medications dont replace lifestyle change. They lower the biologic resistance to it."
X Link 2026-02-14T15:56Z 14.2K followers, [----] engagements
"When Influencers Replaced Scientists https://open.substack.com/pub/tsimpson/p/when-influencers-replaced-scientistsr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true https://open.substack.com/pub/tsimpson/p/when-influencers-replaced-scientistsr=9aucc&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true"
X Link 2026-01-11T00:16Z 14.2K followers, 25.5K engagements
"Yeah thats not how credibility works. Calling someone a leading voice does not make it soespecially when the work in question repeatedly misuses data ignores denominators invents excess deaths and fails basic epidemiology. A few reality checks: Nicolas Hulscher is not a physician and has no formal training in epidemiology. Substack is not a credential. Rebranding blog posts as data analysis does not turn ecological fallacies and spreadsheet errors into science. Being affiliated with advocacy groups like the McCullough Foundation signals ideology first evidence second. Translating complex"
X Link 2026-01-27T03:50Z 13.8K followers, 40.9K engagements
"Ah yesthe classic conspiracy where millions of doctors and pharmacists across every country secretly agree to keep people sic by not recommending a cheap vitamin anyone can buy at Costco. A few facts for the adults in the room: Simon Goddek mistakes bravado for evidence. Doctors dont lose money when your vitamin D is normal. Thats not how medicine or math works. [----] IU daily long-term is not benign. Hypercalcemia kidney stones and kidney injury are well-documented. Large randomized trials show no extra benefit from pushing levels high once deficiency is corrected. Although there is a down"
X Link 2026-01-27T03:58Z 13.7K followers, 60.5K engagements
"This is profoundly misleading and borders on defamatory. Hospitals do not profit from harvesting organs. Organ procurement is handled by independent nonprofit Organ Procurement Organizations (OPOs) under federal law. Hospitals are reimbursed for the care of living patients not for organs. Transplants are cost centers not cash cows. They are labor-intensive heavily regulated outcome-tracked and often reimbursed below cost once long ICU stays complications and lifetime immunosuppression are accounted for. Cancer is not a business line. It is a diagnostic category spanning hundreds of diseases"
X Link 2026-01-27T20:38Z 13.8K followers, [----] engagements
"South Carolina now leads the nation in measles cases: [---] and counting. This didnt happen because the virus changed. It happened because vaccination stopped. Hundreds quarantined. Federal aid deployed. Elimination status at risk. It did not happen because South Carolina is flooded with people from across the border with measles except the unvaccinated Americans who went overseas and brought it back. This is not a mystery. It is the predictable outcome of treating anecdotes influencers and onions as substitutes for public health. https://twitter.com/i/web/status/2016645828128157983"
X Link 2026-01-28T22:53Z 13.7K followers, [----] engagements
"Listing PubMed papers is not an argument; its rsum worship. Peter McCullough published extensively before [----] in cardiology. So did thousands of other competent specialists. That history does not confer authority in virology immunology epidemiology or vaccine safety nor does it grant a lifetime exemption from error. His current posture however is not merely outside his expertiseit is actively anti-science: rejection of population-level outcome data elevation of anecdotes over controlled evidence and a conspiratorial framing that treats consensus as corruption rather than the hard-won product"
X Link 2026-01-29T05:27Z 13.7K followers, [----] engagements
"You cannot blame Robert F. Kennedy Jr. alone for those choicesbut you also cant pretend he was absent. For years he was one of the most visible figures in the anti-vaccine and anti-MMR movement promoting claims that contradicted overwhelming evidence and helping normalize distrust of routine childhood vaccination. And when outbreaks began appearing he had a clear opportunity to change course. From a powerful bully pulpit he could have urged vaccination emphasized community protection and helped close immunity gaps. He did not. So no this isnt the result of one man or one moment. But he"
X Link 2026-01-29T22:07Z 13.7K followers, [----] engagements
"There is no species-appropriate carnivore diet for humanswere omnivores by anatomy enzymes anthropology and outcomes data. If carnivore truly fixed appetite regulation and insulin resistance GLP-1s wouldnt outperform it in randomized trials. Biology isnt impressed by ideology. @drterrysimpson Absolutely advocate the species appropriate diet for humans which is carnivore. you wouldn't need GLP-1 on a carnivore diet @drterrysimpson Absolutely advocate the species appropriate diet for humans which is carnivore. you wouldn't need GLP-1 on a carnivore diet"
X Link 2026-01-31T14:42Z 13.8K followers, [----] engagements
"High triglycerides are driven by energy surplus and insulin resistancewith major contributors including refined carbohydrates alcohol obesity genetics and metabolic disease. Dietary fat does not directly raise triglycerides but saturated fat increases ApoB and LDL which predicts cardiovascular events. Metabolism isnt a bacon-vs-carbs slogan; its measurable physiology. Might I suggest a course in basic physiology @drterrysimpson High trigs are caused by a carb diet not by Bacon and butter https://t.co/FbwuGGauAB @drterrysimpson High trigs are caused by a carb diet not by Bacon and butter"
X Link 2026-01-31T15:01Z 13.8K followers, [----] engagements
"Facultative carnivore is an ecological feeding descriptor not a biological or taxonomic classification. It describes animals that can rely heavily on meat when needed but are not restricted to it. Humans are classified biologically and anthropologically as omnivoresby dentition enzymes gut length isotopes and population outcomes. Flexibility identity. Survival capacity species definition. You wishing to be a carnivore doesn't make it true - @drterrysimpson False. Facultative Carnivore is a biological classification of which the genus homo is a member. You confuse obligate with facultative."
X Link 2026-01-31T15:17Z 13.7K followers, [----] engagements
"You continue to misinterpret what I say by pulling lines out of context and then arguing against claims I didnt make. I did not say carnivore diets cause hypertriglyceridemia. I stated the uncontroversial fact that severe hypertriglyceridemia causes pancreatitis. Reversing that is your error. Yes low-carbohydrate diets can lower triglycerides in some insulin-resistant patients. That does not make high-saturated-fat diets universally safe. In many phenotypeshepatic steatosis genetic dyslipidemia baseline hypertriglyceridemiasaturated fat increases liver fat VLDL output ApoB and triglyceride"
X Link 2026-01-31T15:39Z 14.1K followers, [----] engagements
"Peter Attia now appears in released Epstein-related emails. When a public figure is connected to material involving a known child predator transparency matters. If there is nothing to hide the simplest response is to release the emails in full. The public deserves to know: What he knew When he knew it And if he was aware of child predation whether he followed the ethical and legal duty as a physician to report it This is not about guilt by association. It is about accountability professional ethics and trust. When patients are paying extraordinary fees for access and credibility those"
X Link 2026-01-31T21:52Z 13.9K followers, 75.9K engagements
"As a Californian I wouldnt trade a state with the highest peak in the continental US for one whose highest point is a landfill with zoning approval. Now lets do math not vibes. California is the 4th largest economy on Earth. Bigger than Germany. Bigger than Japan. Florida isnt in the same sentence. California is a net donor to the federal government. We send tens of billions more to DC than we get back. Florida is a net taker. You cash the checks we write. California: Worlds leading innovation economy Produces 14% of US GDP Feeds powers entertains and funds the country Ports that move the US"
X Link 2026-01-31T22:15Z 13.9K followers, 564K engagements
"@MasalaFry69 @PaulCarpFisher Tell me youve never taken a course in epidemiology or biostatistics without telling me"
X Link 2026-02-01T14:35Z 13.7K followers, [--] engagements
"@OminousTheTruth Best public schools 4th largest economy in the world 75% of agriculture 37% of new businesses in the US best health care- its not just the geography we invest in people and pull people up"
X Link 2026-02-01T14:45Z 13.9K followers, 15.3K engagements
"Calling fiber inflammatory is a mechanistic fairy tale told by people who dont read outcome data. Populations that eat more fiber live longer have less heart disease less diabetes and less colon cancer. If fiber truly blocked vitamins and bile acids in any clinically meaningful way deficiency and harm would be obvious in decades of cohort data. They arent. This isnt heresy its just evidence. When your argument collapses at the level of population outcomes its ignorance with confidence. @drterrysimpson Fibre is bad for us. It's inflammatory blocks the absorption of fat soluble vitamins A D E"
X Link 2026-02-02T00:04Z 13.8K followers, [----] engagements
"Fiber isnt an essential nutrient is a semantic dodge not a scientific argument. Neither is exercise sunlight or sleep essential in the deficiency-disease sense yet lacking them reliably shortens lives. Fiber doesnt cause a deficiency syndrome; it prevents diseases. When you reduce nutrition to scurvy logic and ignore population outcomes youre being deliberately obtuse. https://twitter.com/i/web/status/2018114241014960610 https://twitter.com/i/web/status/2018114241014960610"
X Link 2026-02-02T00:08Z 13.8K followers, [----] engagements
"Another Gary Brecka wellness fortune cookie dressed up as endocrinology. Cortisol is regulated by the HPA axis not by mineral vibes. There is NO clinical evidence that sea salt water or vague electrolyte gaps normalize pathological cortisol. Magnesium may help sleep in deficient patientsnothing more. If high cortisol were fixed by sunlight breathing and salt Cushings syndrome wouldnt exist and endocrinologists would be out of work. Mechanisms without outcomes are not medicine but Gary is doing what he does best - making up diseases and then he does the marketing. High cortisol fixes: 1."
X Link 2026-02-02T05:18Z 13.9K followers, [----] engagements
"Posting a Zenodo PDF doesnt overturn decades of population data. Aluminum adjuvants dont cause autism. This claim survives only where peer review is avoided. Aluminum adjuvants can and do cause autism: https://t.co/JI2zReg7ce @ChildrensHD @CHDTVLive @SecKennedy @HHS_Jim Aluminum adjuvants can and do cause autism: https://t.co/JI2zReg7ce @ChildrensHD @CHDTVLive @SecKennedy @HHS_Jim"
X Link 2026-02-02T05:20Z 13.7K followers, [----] engagements
"Longevity gurus sell certainty. Science sells boring wins. Real longevity isnt peptides rapamycin cosplay ice baths or supplement stacks with no human outcome data. What actually works in humans: Mediterranean or DASH eating patterns Normal blood pressure ApoB [--] mg/dL (lower if high risk) Dont smoke Dont drink alcohol Move your body sleep repeat There is no biohack https://twitter.com/i/web/status/2018339061413613865 https://twitter.com/i/web/status/2018339061413613865"
X Link 2026-02-02T15:01Z 13.9K followers, 19.8K engagements
"Claim (repeated by RFK Jr): The Amish dont have autism because they dont vaccinate based on Dan Olmsteds study. Reality: Olmsted never conducted a study no screening no records no diagnostics no peer review. Just anecdotes. When Amish communities were actually examined autism rates were the same as other populations. If no one looks you can make up anything. Claim fails. Data wins. https://twitter.com/i/web/status/2018712206960136255 https://twitter.com/i/web/status/2018712206960136255"
X Link 2026-02-03T15:44Z 13.7K followers, 55.3K engagements
"Facts that dont go away: Statins inhibit HMG-CoA reductase yes the mevalonate pathway and that mechanism is exactly why they work. The downstream effects ( isoprenoids prenylation) have been studied for decades. This is not hidden or denied. Large outcome trials and meta-analyses (CTT Collaboration Cochrane JAMA Lancet) show clear reductions in MI stroke and CV mortality proportional to LDL/ApoB lowering. Claims of manipulated data collapse under replication: benefits appear across populations sponsors and trial designs. If statin trials were sham science we wouldnt see: Consistent"
X Link 2026-02-03T16:28Z 13.8K followers, [----] engagements
"The most nutrient dense - you hear this nonsense from everyone who eats carnivore - and when they say nutrient dense what do they mean Iron - we only can use so much. Choline something the body makes. Is it nutrient dense with anti-oxidants - nope magnesium - no. Want to go down a list of course they don't. But they think eating a steak is manly and eating vegetables is not - or they have not gotten out of their grade school habit of rejecting them. Grow up eat a balanced diet and stop thinking you are doing well - you are not. @vhs0 @drterrysimpson I'm eating the most nutrient dense food"
X Link 2026-02-03T17:22Z 13.9K followers, 13.9K engagements
"Nice duck You want some point by point of her claims - yet again. This is a textbook case of mechanism laundering.Yes statins inhibit HMG-CoA reductase and touch the mevalonate pathway. Thats been known for 40+ years. Listing downstream intermediates (FPP GGPP dolichol heme A IPP) is not a revelation. Its biochemistry cosplay unless you connect it to hard clinical the problem for the argument: RCT reality beats pathway poetry. Across dozens of large blinded statin RCTs (hundreds of thousands of patients) we see consistent reductions in MI stroke and all-cause mortality. If these pathway"
X Link 2026-02-03T20:15Z 13.9K followers, [----] engagements
"No proper human diet was not a claim of chaos it was a rebuttal to dietary absolutism. If carnivore were the proper human diet populations eating fiber-rich omnivorous diets wouldnt have the longest lifespans and lowest cardiometabolic disease. Biology refutes the slogan. Outcomes finish the argument. "First there is no proper human diet." Okay. Got it. Every other species got one. but well you should just take this dude's pills and adviceno matter how hard they are to swallowbecause humans don't have a diet. Wait. dammit did I fall for another one of those satire "First there is no proper"
X Link 2026-02-03T20:18Z 13.7K followers, [----] engagements
"This isnt diet nihilism or absolutism its evolutionary reality. Humans didnt evolve one rigid diet; we evolved flexibility within physiological bounds. When tested against outcomes fiber-containing omnivorous diets repeatedly outperform exclusionary extremes. @drterrysimpson It is not a rebuttal of diet absolutism; it is diet absolutism. And it flies in the face of science in the same way as veganism and carnivorism @drterrysimpson It is not a rebuttal of diet absolutism; it is diet absolutism. And it flies in the face of science in the same way as veganism and carnivorism"
X Link 2026-02-03T20:27Z 13.9K followers, [---] engagements
"Yes similar to Lovastatin first generation statin. Monacolin K has all of the side effects of any statin as a first generation it had the most and not as efficacious as later ones. Buying red rice yeast is about 20-40 dollars while my Crestor costs less than a dollar a month has fewer side effects lowers LDL more decreased risk of cardiovascular events and [--] % decreas in the risk of dementia. @YatYas1070 @drterrysimpson This is monacolin K. Please reply with the structure of monacolin K from red yeast: https://t.co/T5ryCEbLwr @YatYas1070 @drterrysimpson This is monacolin K. Please reply with"
X Link 2026-02-03T21:22Z 13.9K followers, [----] engagements
"Inuit mummies show atherosclerosis. Modern Inuit biology is well studied. Even today among Alaska Native populationsdespite better infant survivallife expectancy remains below the U.S. average. This isnt conjecture. Its population data. Survivorship bias longevity. @drterrysimpson I've done the work. Perhaps you should as you are the one in error. Hunter-gatherers who survive childhood typically live to be old: their most common age of death is between sixty-eight and seventy-two and most become grandparents or even great-grandparents. There's been @drterrysimpson I've done the work. Perhaps"
X Link 2026-02-03T23:50Z 13.9K followers, [----] engagements
"This is mechanism laundering. It strings together true chemistry terms to imply clinical harm that does not show up in human outcomes. 1) Saturated fat has no double bonds so its stable True. Irrelevant. Chemical stability in a test tube biological effect in humans. 2) PUFAs have double bonds that oxidize into lipid peroxides Partly true in vitro. But in living humans: PUFAs are packaged in lipoproteins Protected by antioxidants (vitamin E glutathione enzymes) Rapidly repaired and turned over If this claim were true at scale PUFA intake would correlate with higher disease and mortality. It"
X Link 2026-02-04T13:25Z 13.7K followers, [----] engagements
"Whats actually wrong with the chart [--]. Vitamin A bait-and-switch Beef liver is loaded with preformed retinol Kale contains beta-carotene a regulated precursor The body down-regulates beta-carotene conversion when stores are adequate. Retinol No such brake toxicity risk with regular liver intake. Nutrition highest number wins [--]. Portion distortion Most of these charts compare: [---] g beef liver (a pharmacologic dose) [---] g raw kale (not how people eat it) Nobody eats liver daily at that dose without consequences. Not to mention it tastes vile. [--]. Selective vitamin scoring They highlight: B12"
X Link 2026-02-04T15:16Z 13.9K followers, [----] engagements
"Calling me a poor student isnt evidence. And that quote doesnt prove ancestral diets = no heart disease. In Alaska Native/Inuit data (that I review for our tertiary system): some eat traditional some dontbut vascular disease isnt new and life expectancy still trails the Lower [--]. Economic progress doesnt require diabetes/CVDbut neither does it erase biology infection burden trauma smoking housing and access. @drterrysimpson @michael_trumper Again you are wrong. You claim your knowledge comes from your anthropology backgroundbut you must have been a poor student. As I already posted from one"
X Link 2026-02-04T18:15Z 13.9K followers, [----] engagements
"Ancestral diet = no CVD is a slogan not a mechanism. Low-CVD groups share a risk profile: low ApoB/LDL high activity low smoking/BP/obesity minimal ultra-processed foods. The cleanest causal evidence in humans remains lifelong low ApoB/LDL (incl. PCSK9 LOF). Insults arent data. I've read the whole paper and all the related papers and an enormous amount of the research that gives it context. Like what do we know causes CVD and obesity in humans that these people (and every other ancestral group with low CVD) doesn't eat Unlike you who continues to I've read the whole paper and all the related"
X Link 2026-02-04T23:30Z 13.9K followers, [----] engagements
"Calling this ignorance requires pretending history diagnostics and epidemiology dont exist. Yes myocardial infarction can be identified at autopsy todaybecause we now know what to look for. In [----] physicians did not. There were no ECGs no cardiac enzymes no coronary angiography and MI was not a standard diagnostic category. Most events were labeled sudden death heart failure or missed entirely. And noautopsy practice at one hospital was not universal medicine. Autopsy rates varied wildly by region hospital culture and consent. A Massachusetts teaching hospital is not a proxy for the United"
X Link 2026-02-05T13:10Z 13.9K followers, [----] engagements
"And someone who calls carbs evil - imagine the healthiest people in the world and longest living dont know this But this fellow does - amazing You know what else improves weight control retard Knock off the carbs retard. You know what else improves weight control retard Knock off the carbs retard"
X Link 2026-02-05T17:02Z 13.7K followers, [----] engagements
"Serious mental illness isnt cured by a diet. Ketogenic diets are being studied as possible adjuncts under medical supervisionnot as replacements for psychiatric care. If you have bipolar disorder or schizophrenia seek evidence-based treatment not internet nutrition advice. RFK Jr.: Dr. Pollan up at Harvard has cured schizophrenia using keto diets. here are studies right now that I saw two days ago where people lose their bipolar diagnosis by changing their diet. https://t.co/pGuMghJKPa RFK Jr.: Dr. Pollan up at Harvard has cured schizophrenia using keto diets. here are studies right now that"
X Link 2026-02-05T17:26Z 13.8K followers, [----] engagements
"Yes debate someone- always the cry of someone who doesnt want to do the hard work of reading the literature no they want to score points with logic - show the data not the dogma and if those peer reviewed studies contradict then let a new model arise - until then let the adults talk Well dickwad. Why not live debate my friend 'Baldy'. He will tear you seven new assholes he's a cardiovascular pathophysiologist btw. In this objective reality what I said is STILL CORRECT and you have NOT refuted it retard. You have repeated your incorrect opinion again. Well dickwad. Why not live debate my"
X Link 2026-02-05T17:33Z 13.7K followers, [----] engagements
"When your argument is this one guy is healthy youre not doing scienceyoure doing storytelling. Nutrition is evaluated in populations over decades with hard endpoints. Evidence beats vibes.and education isnt a bad thing - beats the alternative Nutritionist's credentials: - [--] years studying food pyramid (designed by grain lobby) - Memorized that fiber is essential (it isn't) - Learned cholesterol is dangerous (it isn't) - Taught saturated fat clogs arteries (it doesn't) - [-----] in student debt - BMI of [--] - Takes Nutritionist's credentials: - [--] years studying food pyramid (designed by grain"
X Link 2026-02-05T18:17Z 13.7K followers, [----] engagements
"Ever wonder why the same gym bro is selling you a peptide to inject one that isn't regulated has no testing - advises you against having ice on an airplane"
X Link 2026-02-05T21:09Z 13.8K followers, [----] engagements
"Jeffrey Epstein has reached into the medical world with prominent doctor @PeterAttiaMD :"
X Link 2026-02-06T00:28Z 13.7K followers, [----] engagements
"You can always tell when someone hasnt read Ancel Keys work. Ancel Keys did not sit on a pristine 22-country dataset and maliciously hide the naughty ones. In [----] most countries simply did not have reliable age-adjusted coronary mortality data. Garbage in garbage out is not censorship its statistics. The graph was hypothesis-generating which Keys explicitly said. Treating it as a randomized global trial is like blaming Darwin for not sequencing DNA. When Jacob Yerushalmy re-analysed the ecological data he didnt make the fat-heart relationship disappear. He showed what every competent"
X Link 2026-02-06T14:33Z 13.7K followers, [----] engagements
"@vincristine @Ancestral_Coach There is none and he clearly has not looked at vaccine trials but has taken the lazy way out by parroting nonsense"
X Link 2026-02-06T20:16Z 13.7K followers, [--] engagements
"The Lancet meta-analysis examined [--] placebo-controlled randomized trials involving [------] participants assessing [--] additional adverse outcomes beyond the well-known effects of statins such as myalgias and diabetes risk effects that were already acknowledged and reported. When dozens of outcomes are tested random variation is inevitable. That is why false discovery rate corrections exist: to prevent ordinary statistical noise from being mislabeled as biological harm. This is not suppression. It is basic epidemiology. The repeated emphasis on almost significant findings is not a scientific"
X Link 2026-02-07T15:37Z 13.8K followers, 11.4K engagements
"This is a straw man wrapped in sarcasm. No serious physician believes disease is a pharmaceutical deficiency. That line exists only to avoid engaging with what medicine actually says. Poor nutrition does affect brain health. So do hypertension diabetes smoking alcohol sleep apnea genetics and aging. Multiple causes can coexist. Adults learn this early. Diet can improve risk factors. It does not cure atherosclerosis Alzheimers pathology Parkinsons disease or genetic hyperlipidemia once established. Claiming otherwise is not rebelliousits biologically illiterate. Also worth noting the source."
X Link 2026-02-07T15:48Z 13.9K followers, [----] engagements
"@dr_jon_l I thought Trump was the daddy"
X Link 2026-02-07T15:49Z 13.7K followers, [--] engagements
"To P. Jeffrey Ungar PhD Your claim collapses at the first factual checkpoint. Ancel Keys did not have a complete valid age-adjusted 22-country coronary mortality dataset in [----]. What existed were heterogeneous national statistics riddled with misclassification missing age structure and incompatible dietary estimates. Excluding garbage is not cherry-picking; its competence. Jacob Yerushalmy did not show the fatheart relationship basically vanished. He showed ecological correlations are unstable a point Keys himself made. Yerushalmy did not disprove lipid causality nor did he propose an"
X Link 2026-02-07T15:51Z 13.7K followers, [----] engagements
"To Bryan Krantz Calling Ancel Keys unethical only works if you quietly assume facts that arent true. Keys was not caught manipulating data. There was no fabricated dataset no altered numbers no hidden files later exposed. What youre describing is methodological disagreement retroactively reframed as moral failure. In the 1950s: Ecological data were incomplete and inconsistent Coronary death certification varied wildly by country Age adjustment was often impossible Dietary intake estimates were crude at best Excluding unreliable data is not misconduct. Its standard practice then and now. If"
X Link 2026-02-07T15:53Z 13.7K followers, [----] engagements
"One crucial correction: if he had actually followed Keys this likely wouldnt have happened.Ancel Keys never promoted a low-fat sugar-heavy ultra-processed diet. His early books describe what we now call a Mediterranean diet: olive oil nuts legumes vegetables whole grains fish modest meat minimal sugar minimal industrial food.That pattern has been repeatedly validated by later research.What harmed people wasnt Keys diet. It was the misinterpretation of it into low-fat dogma and the industrial food industrys response: fat-free sugar-dense ultra-processed junk none of which appears in Keys"
X Link 2026-02-07T15:57Z 13.7K followers, [----] engagements
"Thimerosal is ethylmercury not methylmercury. Its cleared rapidly doesnt bioaccumulate and was removed from routine childhood vaccines over [--] years ago autism rates kept rising anyway. The CDC didnt get busted. Multiple independent studies across countries found no link between thimerosal and neurodevelopmental harm. Repeating look it up isnt evidence. Its what people say when they havent. You dont get to hand-wave away randomized trials pharmacokinetics and population data with vibes and insults. Science doesnt work that way even when yelling feels good. @drterrysimpson @vincristine"
X Link 2026-02-07T15:59Z 13.7K followers, [----] engagements
"Laughing isnt an argument. Insults arent data. And yelling shill is what people do when theyve run out of facts. Ancel Keys didnt hide data. In [----] most countries lacked reliable age-adjusted coronary mortality statistics. Excluding unusable data is statistics not corruption. If the dietheart hypothesis were built on fraud it wouldnt have survived genetics mechanism prospective cohorts and randomized outcome trials. It did repeatedly long after Keys was gone. And heres the part you keep proving: youd actually have to read Keys to know what he said studied or did. You havent. This isnt about"
X Link 2026-02-07T16:03Z 13.7K followers, [---] engagements
"False. Statin trials did not pre-remove people who had side effects. Run-in periods sleaze. Theyre used across RCTs to reduce noise from early non-adherence and improve internal validity before randomization. Key point critics keep missing: Serious statin harms are adjudicated after randomization and analyzed by intention-to-treat. They are not pre-removed. If statin side effects were a major hidden signal youd expect to see it in: blinded placebo-controlled trials genetic randomization (LDL-lowering variants) pharmacoepidemiology across millions of patients We do not. Greenland McShane and"
X Link 2026-02-07T16:08Z 13.9K followers, 14.3K engagements
"Glucose is not a toxin. But everything has a toxic level: oxygen water salt glucose and cholesterol. That fact does not negate benefits - it puts it in perspective and to ignore it is simple ignorance. Cholesterol is not a toxin. Its a structural molecule your body cannot function without. Cholesterol is not a toxin. Its a structural molecule your body cannot function without"
X Link 2026-02-07T16:12Z 13.9K followers, [----] engagements
"Show me you don't understand SV40 promoters without telling me you don't understand them. "The mRNA vaccines are all completely contaminated.the Pfizers are all full of SV40" Dr. Angus Dalgleish Oncologist "SV40 was what in my day we put into mice to make them grow tumors.& we're putting this into humans" "These people behind Pfizer & Moderna are pure evil" https://t.co/r7IXwakpII "The mRNA vaccines are all completely contaminated.the Pfizers are all full of SV40" Dr. Angus Dalgleish Oncologist "SV40 was what in my day we put into mice to make them grow tumors.& we're putting this into"
X Link 2026-02-07T16:13Z 14.1K followers, [----] engagements
"This is a nurse not a doctor - and she is simply wrong. She cannot describe what to do with a patient who cannot get enough oxygen to maintain life - she would not put them on a vent Would she let them die That is the alternative. We did learn a lot about treating covid we made some mistakes but what emptied the hospitals was the vaccine. But do tell how to manage covid without vaccine do tell what they should have done - this isn't a real trained physician who understands physiology this is a nurse who couldn't tell you the basics of pulmonary physiology but claims to know more than the"
X Link 2026-02-07T16:16Z 13.8K followers, 19.5K engagements
"Kind of shows you how well the vaccine works eh Exposing the tetanus hoax - In the last decade [--] died from tetanus in the US. - It's a vaccine that can be taken at the time of injury. Yet babies are given [--] shots. - The risk is that [--] in [---] million will die from tetanus. A Big Pharma scam https://t.co/yU97AQ4H3o Exposing the tetanus hoax - In the last decade [--] died from tetanus in the US. - It's a vaccine that can be taken at the time of injury. Yet babies are given [--] shots. - The risk is that [--] in [---] million will die from tetanus. A Big Pharma scam https://t.co/yU97AQ4H3o"
X Link 2026-02-07T16:24Z 13.7K followers, [----] engagements
"Bedside care is not competence to determine if a patient should be intubated or not. Nor should one assume they have the competence to determine what pharmacologic interventions are needed. Often we were called by the nurses to intubate patients who failed prone positioning and were close to coding. Yes we were given a lot of bad advice like not to use steroids or NSAID - but we did what we do and tested those and found better ways to do things. The anti-vax tropes use our inability to provide definitive care against us to say we killed patients with this novel virus as a mass slaughter - and"
X Link 2026-02-07T21:18Z 13.7K followers, [---] engagements
"@dr_jon_l @drtaubraun Does Santa exist in this fantasy"
X Link 2026-02-08T03:52Z 13.7K followers, [--] engagements
"@dr_jon_l @KenDBerryMD Alas their cult leader is exempt from such rules"
X Link 2026-02-08T03:56Z 13.7K followers, [--] engagements
"Yes this doctor who makes all of his patients see a chiropractor once a week and sells supplements found the secret. He is such a lightweight The real cause of heart disease has been buried for decades in favor of the lie about cholesterol. [--] million Americans take statins to lower their cholesterol thinking its the best way to protect their hearts. But what doctors never tell them is that statins interfere with The real cause of heart disease has been buried for decades in favor of the lie about cholesterol. [--] million Americans take statins to lower their cholesterol thinking its the best"
X Link 2026-02-08T03:59Z 13.9K followers, [----] engagements
"Tell me you have not been to Iceland without telling me Iceland: Fourth highest life expectancy globally (83 years). Traditional Icelandic diet: - Fatty lamb - Fatty fish (salmon herring) - Butter - Skyr (high-protein dairy) - Liver - Blood pudding - Fermented shark - Dried fish Virtually no vegetables for most of the year https://t.co/UuC5pGvFCj Iceland: Fourth highest life expectancy globally (83 years). Traditional Icelandic diet: - Fatty lamb - Fatty fish (salmon herring) - Butter - Skyr (high-protein dairy) - Liver - Blood pudding - Fermented shark - Dried fish Virtually no vegetables"
X Link 2026-02-08T04:00Z 14.2K followers, 11.5K engagements
"I would suggest a carnivore lifestyle is a mental health disorder - orthorexia nervosa 8-10 years ago several of us were observing significant mental health improvements among those adopting low carb/keto/carnivore diets - we were often ridiculed even among many in low carb community Today most in the low carb community concede that this does indeed happen We are 8-10 years ago several of us were observing significant mental health improvements among those adopting low carb/keto/carnivore diets - we were often ridiculed even among many in low carb community Today most in the low carb"
X Link 2026-02-08T04:06Z 13.9K followers, [----] engagements
"@drtaubraun @dr_jon_l Dont show that my son doesnt know I am he"
X Link 2026-02-08T04:11Z 13.7K followers, [--] engagements
"Added sugar in the diet should be kept to a minimum - about [--] grams per day for men and [--] for women is the latest. That is added. Diabetics do quite well with whole grains fruits and vegetables. Everyone is slightly different but total avoidance of fruits whole grains and vegetables is advocated by those who do not read the literature"
X Link 2026-02-08T15:53Z 13.8K followers, [--] engagements
"@BornFree_isms @dr_jon_l @FLSurgeonGen So did he get a license to practice medicine or is he just allowed to apply"
X Link 2026-02-08T17:31Z 13.7K followers, [--] engagements
"No serious scientist says every debate is closed. What we say is that the totality of evidence is sufficient to guide clinical practice. On salt and blood pressure: Mechanistic data Metabolic ward studies Population studies Randomized trials Mendelian randomization Outcome reductions in stroke and heart failure All point in the same direction. Yes individual response varies. Yes sodium sensitivity exists. No that does not make the evidence messy in the way Taubes implies. Calling an issue still debated does not negate decades of convergent evidence. Its how controversy entrepreneurs keep"
X Link 2026-02-08T17:46Z 13.9K followers, [----] engagements
"Its hard to make ethical critiques when you only know half the history. Anti-Coronary Club Voluntary transparent non-randomized. Purpose: diet cholesterol not mortality. It succeeded at exactly what it set out to test. Minnesota Coronary Survey Randomized double-blind feeding trial in hospitals/nursing homes. Result: LDL fell significantly. No short-term mortality signal in an elderly institutionalized population refutation of lipid causality. Key facts critics omit: Ancel Keys was not the PI on MCS Data were published not hidden Short duration + late-life intervention + competing risks"
X Link 2026-02-08T17:49Z 13.8K followers, [---] engagements
"@dr_jon_l I feel sorry for the people of Florida. Maybe ICE will send him away"
X Link 2026-02-08T18:14Z 13.8K followers, [---] engagements
"@KingManninen agree [---] percent"
X Link 2026-02-08T18:23Z 13.8K followers, [---] engagements
"Youre still substituting mechanistic plausibility for clinical sufficiency. No one disputes that food quality can influence: satiety signaling (PYY GLP-1) insulin resistance and lipid markers likelihood of passive overconsumption Those are adjunctive effects not proof of durable obesity remission. What should have settled this debate is GLP-1 trial data. When we pharmacologically amplify satiety slow gastric emptying and reduce food noiseoften without changing food qualitypatients lose 1525% of body weight with durability while treatment continues. That effect size exceeds any diet-quality"
X Link 2026-02-08T18:29Z 13.9K followers, [----] engagements
"@AdrianViti @BroChillerman DASH was a study of that diet with and without salt restriction - showing salt influence in real world eating made a difference- not off topic"
X Link 2026-02-08T22:06Z 13.8K followers, [--] engagements
"@MonardaB Its more dangerous to some - it has an effect. The analogy is alcohol- most dont get liver issues but that doesnt mean its benign"
X Link 2026-02-09T08:06Z 14K followers, [--] engagements
"Obesity is a disease and you can become obese on fat and protein @luckynoelle @drterrysimpson @grok is obesity a disease Or an addiction to sugars Can you get obese on fat and protein @luckynoelle @drterrysimpson @grok is obesity a disease Or an addiction to sugars Can you get obese on fat and protein"
X Link 2026-02-09T16:00Z 13.9K followers, [----] engagements
"The Mediterranean Diet has 13000+ peer-reviewed publications in the last decade alone. Claiming it does not exist simply means you havent read the literature or dont understand how dietary patterns are defined and measured in science. And when people disparage Ancel Keys its usually the same tell. Keys did not invent the Mediterranean diet. He described and studied existing dietary patterns associated with lower cardiovascular mortality. If you've done the research you would know this but the basics of research is becoming familiar by reading the primary material. Clearly you have not."
X Link 2026-02-09T16:03Z 13.9K followers, [----] engagements
"1. Stomach pH misused and misunderstood Yes fasting human stomach pH can approach [--]. That does not make us carnivores. Stomach acid diet category Acid sterilizes food and activates pepsin. It evolved to reduce pathogen risk in omnivores and scavengers not just carnivores. True obligate carnivores (cats) cannot survive without taurine vitamin A arachidonic acid and preformed DHA. Humans synthesize or obtain these from mixed diets including plants. Human gastric pH rises substantially after meals unlike obligate carnivores that maintain extreme acidity. Bottom line: Acid carnivory. It reflects"
X Link 2026-02-09T16:14Z 13.9K followers, 14.1K engagements
"@Do_335_A1_Cuba how do you even use grok"
X Link 2026-02-09T16:29Z 13.9K followers, [---] engagements
"The claim that a meat-only diet put Crohns disease into remission mistakes anecdote for evidence and physiology for wishful thinking. Crohns is a relapsing inflammatory disease with spontaneous remissions regression to the mean medication effects and placebo responsesnone of which magically disappear because someone ate steak for a few months. There is no credible evidence that an all-meat diet induces mucosal healing alters the underlying immune pathology or produces durable remission and plenty of reasons to worry about nutritional deficiencies and long-term harm. Confusing personal"
X Link 2026-02-09T16:32Z 13.9K followers, [---] engagements
"Of all the people they could have used for a Superbowl commercial they had someone who served time in prison for rape. Do better"
X Link 2026-02-09T16:38Z 13.9K followers, [----] engagements
"@SandmanRT I would hypothesize that ultra processed food sets off a cascade and for which some people myself included triggers the path. Woodstock was great by the way - a bit muddy in the end"
X Link 2026-02-09T19:22Z 13.9K followers, [--] engagements
"@HRH_Ted apparently you have not. Again do you have a doctorate Do you know how to use pub med"
X Link 2026-02-09T20:31Z 13.9K followers, [---] engagements
"This is backwards. Yes every cell makes cholesterol. Thats exactly why blood LDL levels arent neededcells synthesize what they require. What matters for arteries is how many ApoB/LDL particles are circulating and entering the vessel wall (thats the causal pathway for ASCVD) not whether cholesterol exists. Higher cholesterol live longer is usually confounding + reverse causation in older/ill populations (frailty inflammation cancer malnutrition can lower cholesterol before diagnosis). Observational longevity claims LDL is protective. Lowering LDL does not raise Alzheimers risk. The best"
X Link 2026-02-09T20:37Z 13.9K followers, [----] engagements
"And yet in the most recent studies the plaque growth of patients on extreme low carb patients was rapid. To take exception with all the people who study this without providing evidence is a dangerous public position. Youre delusional if you think there is an ER full of people on a carnivore diet having heart attacks-I wouldnt be surprised if their rate of MIs are significantly lower than the general population. Youre delusional if you think there is an ER full of people on a carnivore diet having heart attacks-I wouldnt be surprised if their rate of MIs are significantly lower than the"
X Link 2026-02-09T20:38Z 13.9K followers, 14.6K engagements
"My [--] yo dog"
X Link 2026-02-09T21:19Z 13.9K followers, [----] engagements
"agree - and here is from @EvidenceOpen "The primary mechanism of weight loss appears to be appetite suppression and reduced energy intake. Semaglutide reduces caloric intake by approximately 35% compared to placebo while liraglutide reduces it by approximately 16%. Recent mechanistic work shows semaglutide activates specific neurons in the dorsal vagal complex that promote fat utilization and reduce food intake but whether this represents metabolic enhancement beyond calorie reduction remains unclear." I do wish it had more magic I'd like to think it brings Hogwarts and the wand says the"
X Link 2026-02-09T22:04Z 13.9K followers, [---] engagements
"This argument fails because it rewrites the trial after the fact. Both arms received the same counseling. One arm lost 15% the other 2.4%. The difference is the drug. Thats not metabolic magic its pharmacology. Claiming the placebo group could have lost 1520% if only theyd tried harder is not analysisits counterfactual wish-casting. In clinical science we analyze what happened not what Twitter imagines might have happened. If poor compliance explains the result you must explain why compliance systematically improved only when GLP-1 signaling was altered. Appetite suppression gastric emptying"
X Link 2026-02-10T01:57Z 13.9K followers, 10.8K engagements
"@sarasteinmd God it is the boring diet of people who have a boring palate or who havent grown up"
X Link 2026-02-10T03:41Z 13.9K followers, [---] engagements
"The charge is theatrical rather than substantive. Waving Gurven & Kaplan (2007) like a talisman does not convert paleoanthropology into clinical nutrition nor does it absolve one from engaging with outcomes that actually kill people in the modern world. Describing how small-scale societies obtained food under conditions of infection trauma and short life expectancy is not the same as demonstrating reductions in cardiovascular events diabetes or mortality. That distinction is not pedantry; it is the difference between storytelling and medicine. Sneering at TikTok surgeons merely advertises an"
X Link 2026-02-10T03:56Z 13.9K followers, [--] engagements
"When someone substitutes profanity for argument its usually because the argument has gone missing. Calories are a unit of energy measured by metabolic effect not something one gnaws on like a croutona distinction understood by every first-year physiology student. Screaming about first principles while misunderstanding them is not rigor; its performance art for the incurious. If abuse were evidence youd have won a Nobel by now. For fuck's sake dry up and blow away you fucking imbecile. It is a physical IMPOSSIBILITY to eat calories. This CANNOT be done you utter moron. Learn some basic first"
X Link 2026-02-10T04:03Z 13.9K followers, [----] engagements
"Or eat reasonably and join the majority that lose fat If You're Thinking of Taking a GLP-1 Read This: Research shows up to 40% of the weight you lose on Ozempic isn't fat. It's muscle. And once it's gone your metabolism pays the price. We built the The High Performance GLP-1 Protocol to fix this. It protects your muscle https://t.co/rYNs7IYsno If You're Thinking of Taking a GLP-1 Read This: Research shows up to 40% of the weight you lose on Ozempic isn't fat. It's muscle. And once it's gone your metabolism pays the price. We built the The High Performance GLP-1 Protocol to fix this. It"
X Link 2026-02-10T04:11Z 13.9K followers, [----] engagements
"What youve done is stack anecdotes selective endpoints and evolutionary romance and then declared victory over medicine. Gurven & Kaplan did not show that hunter-gatherers were thriving into their 70s as a norm; they showed conditional survival after childhood in populations dominated by trauma infection and energy scarcityhardly a model for modern chronic disease prevention. Longevity without antibiotics statins anesthesia or blood pressure control is not proof of dietary supremacy; its proof of survivorship bias. Your keto claims fare no better. A 24% mortality drop without context"
X Link 2026-02-10T04:19Z 13.9K followers, [--] engagements
"The appendix proves nothing of the sort. Humans do not lack a cecum; we have a reduced one and the appendix is not a vestigial shrug but an immune organ rich in lymphoid tissue involved in gut immunity and microbiome regulation. We are not obligate hindgut fermenters like horses or rabbitsno one claims we arebut we do ferment fiber via colonic bacteria producing short-chain fatty acids with measurable metabolic effects. That process is smaller in scale not absent. To leap from humans dont have a cows fermentation chamber to therefore meat is our primary food is anatomical illiteracy. By that"
X Link 2026-02-10T04:21Z 14.1K followers, [----] engagements
"@Papaghostbear Ask any red state that lives in permanent need of places like California to subsidize them through federal taxes"
X Link 2026-02-10T14:59Z 13.9K followers, [----] engagements
"@idrone22 yes like Alabama"
X Link 2026-02-10T15:27Z 13.9K followers, [----] engagements
"This is a standard RCT not a vibes-based wellness retreat. Adherence wasnt assumedit was handled the same way it is in virtually every long-term obesity trial. Both arms received identical lifestyle counseling Energy intake was assessed with validated dietary questionnaires (the same tools used across obesity RCTs) Weight change itself is the objective adherence signalif the placebo group were actually sustaining a [---] kcal/day deficit for [--] weeks you would not see 2.4% loss More importantly: If the explanation were poor compliance youd expect wide variance and some large losers in placebo."
X Link 2026-02-10T16:02Z 13.9K followers, [----] engagements
"Confidence is not a surrogate for evidence. Peter Attia cites literature fluently but citation without synthesis is not expertise. He did not complete residency operates outside clinical consensus and his emphasis on VO max high-protein absolutism and rapamycin exceeds human evidence. In another era this was goat-gland medicinetoday its the same grift just better ring lights and newer tattoos. https://twitter.com/i/web/status/2021273572757676416 https://twitter.com/i/web/status/2021273572757676416"
X Link 2026-02-10T17:22Z 14.1K followers, [----] engagements
"This is a confident monologue built on a false premise: that feeling bad on a diet is proof one simply failed to eat enough of its most extreme component. Rabbit starvation is a real historical phenomenon but invoking it here is a bait-and-switch. Humans do not spontaneously develop protein poisoning because they ate chicken and coffee; they feel unwell because extreme single-macronutrient diets are metabolically narrow socially fragile and biologically unnecessary. The claim that humans need [---] grams of fat a day is not physiology its ideology. There is no requirement in human biology for"
X Link 2026-02-10T20:54Z 13.9K followers, [----] engagements
"@wearecharlie8 Oh its not a dollar for dollar exchange they are quite subsidized by states like California New York and Illinois"
X Link 2026-02-10T21:52Z 13.9K followers, [---] engagements
"Apparently fat-shaming is still in style. Unless of course they come to your course/workout/gym/whatever. God forbid they should get a prescription for a disease which has more efficacy Ozempic is the fastest-growing drug in America. We don't have a healthcare crisis. We have a personal responsibility crisis dressed up as a medical condition. Ozempic is the fastest-growing drug in America. We don't have a healthcare crisis. We have a personal responsibility crisis dressed up as a medical condition"
X Link 2026-02-10T21:57Z 14K followers, 15.6K engagements
"This is what happens when arithmetic is performed without scale category or comprehension. Quoting a few million in taxes versus benefits without specifying who which taxes which benefits or relative to what base is not analysisit is numerology with a political accent. California does not contribute five million dollars in taxes. It contributes hundreds of billions annually in federal revenueincome taxes payroll taxes corporate taxes excise taxesfar more than it receives back in federal spending. The figures you cite are almost certainly a single program slice or a cherry-picked transfer"
X Link 2026-02-10T23:05Z 13.9K followers, [---] engagements
"People leave California because housing is scarce and expensivenot because Alabama suddenly became the economic engine of the United States. Cheap land isnt productivity migration isnt subsidy and square footage is not a balance sheet. And its still Alabama @drterrysimpson @DarkagePossum @idrone22 People are flooding from California to Huntsville. COL is obscenely high. You can get a [--] bedroom mansion in Huntsville for the price of an average home in California. @drterrysimpson @DarkagePossum @idrone22 People are flooding from California to Huntsville. COL is obscenely high. You can get a 10"
X Link 2026-02-10T23:07Z 13.9K followers, [----] engagements
"@dr_jon_l @thereal_truther @CombatingAutism @AgeofAutism Some are pdf filed in their moms basement"
X Link 2026-02-11T00:47Z 13.9K followers, [--] engagements
"Yes they extend to atherosclerosis Low carb diet benefits are beyond weight loss and Diabetes. Low carb diet benefits are beyond weight loss and Diabetes"
X Link 2026-02-11T00:47Z 13.9K followers, [----] engagements
"@wearecharlie8 @AdonicaSS California state is not in debt - you are mixing in local pension debt - that is up to the cities - and is an accounting issue not a typical debt"
X Link 2026-02-11T01:40Z 13.9K followers, [--] engagements
"One of the hardest things to see is my dog as he cannot control his back legs. He is deaf blind and loves every minute with us. Walking is his favorite thing in the world. Instead of going away this weekend I am staying with him. He is on borrowed time so I am going to try to sneak some more time in with him"
X Link 2026-02-11T01:50Z 14.2K followers, [----] engagements
"You have forgotten these things were discussed. LDL receptor status is quite important in therapies but Among other differences I noted that veins likely express fewer LDL receptors but receptor density is not the decisive issue. The arterialvenous difference in atherosclerosis is multifactorial. Arteries operate under higher pressure experience disturbed and oscillatory shear stress have a thicker intima greater smooth muscle cell content and a different extracellular matrix composition particularly proteoglycans that retain apoB particles. LDL entry occurs largely via transcytosis and"
X Link 2026-02-11T02:18Z 13.9K followers, [---] engagements
"@VickieMacFadden They have sold dogma - instead of being helpful. They should focus on working with science but alas"
X Link 2026-02-11T02:22Z 13.9K followers, [---] engagements
"@DrRogerHugh Do show your data if you have some to the contrary but two things have great efficacy for weight loss: surgery and now GLP-1. Exercise is a great adjunct but that is it"
X Link 2026-02-11T02:27Z 14.2K followers, [---] engagements
"@VoidMillennia @HRH_Ted You find his diatribe funny You think his abuse is funny You think he is bright because he says he is and yet doesnt know the basis of causation in medicine And you think that I support and take GLP-1 that this is a bad thing"
X Link 2026-02-11T02:31Z 13.9K followers, [--] engagements
"@VoidMillennia @HRH_Ted Given the abuse Ive received here I see no reason to engage in another conversation. And that you find his abuse amusing is something you should reflect upon. I shall save you some trouble and block you so you dont have to be troubled with modern science"
X Link 2026-02-11T02:49Z 13.9K followers, [--] engagements
"@Chaddadbod Blood test - a common one too"
X Link 2026-02-11T03:33Z 13.9K followers, [--] engagements
"Youre mixing valid philosophy-of-science points with a conclusion that doesnt follow from the evidence we actually have. 1) Correlation can never prove causation (including smoking and cancer). Correlation alone doesnt prove causation. Correct. But medicine doesnt use correlation alone. We use triangulation: temporality + doseresponse + consistency + biological mechanism + reversibility + experiments + genetics. Smoking lung cancer is one of the classic examples where multiple independent lines converge. 2) Burden of proof is on you: LDL causes atherosclerosis. Agreedand that burden has been"
X Link 2026-02-11T15:10Z 14.2K followers, [----] engagements
"It is always nice when you see bits of improvement in your dog. Today he walked up the stairs without assistance and pain notice the new appliance where I can assist him with less back strain. He is quite proud of himself"
X Link 2026-02-11T16:53Z 13.9K followers, [----] engagements
"Since there is no advantage to raw milk other than infectious disease drinking it has all the advantages of hoping the water in the toilet was flushed before you partake of it. When it comes to raw milk two things will most certainly happen lying with statistics and fear mongering the dangers https://t.co/UQBnjae2QI When it comes to raw milk two things will most certainly happen lying with statistics and fear mongering the dangers https://t.co/UQBnjae2QI"
X Link 2026-02-11T16:58Z 14.1K followers, [----] engagements
"Of course vitamin K2 regulates calcium. So do your kidneys. So does parathyroid hormone. So does vitamin D. Regulates calcium is the biochemical equivalent of saying a thermostat controls temperature. It tells you nothing about whether the house is on fire. The claim here is not modest. It is not that K2 participates in gamma-carboxylation of matrix Gla protein. That part is textbook. The claim is that K2 reverses existing vascular calcification and restores elasticity to vessels. That is not a mechanistic statement. That is a clinical one. And where are the randomized trials showing"
X Link 2026-02-11T17:19Z 14K followers, [----] engagements
"@CoachBigBri Glad you lost - however that does not activate GLP-1 and GLP-1 lasts a few minutes then is gone. Synthetic GLP-1 goes through different pathways and lasts days"
X Link 2026-02-11T19:24Z 13.9K followers, [---] engagements
"@underdog1030 The combination works because it: Targets two distinct physiologic pathways Prevents metabolic compensation Maximizes LDL receptor upregulation Achieves lower ApoB particle burden Mechanistically elegant. Clinically validated"
X Link 2026-02-12T14:50Z 14.2K followers, [--] engagements
"@deborahbrian @DevinThorn33342 I dont know or care how people tell the difference in LLM or personal . Its the content not the prose. I use @EvidenceOpen for studies but not for their writing - which is clinical and not narrative"
X Link 2026-02-12T16:50Z 13.9K followers, [--] engagements
"GLP-1s take away vision is misinformation. ADA notes early retinopathy worsening can occur when A1c drops fasta known rapid control effect not proof of drug toxicity. RCT meta-analysis shows no significant increase in vision-threatening events; NAION signals are rare and still being clarified. Monitor eyes dont panic. https://twitter.com/i/web/status/2022001849335975969 https://twitter.com/i/web/status/2022001849335975969"
X Link 2026-02-12T17:36Z 14.2K followers, [----] engagements
"@MalleyGlass Love olive oil - and I don't do many artificial sweeteners because they taste too sweet to me -but looks like damage from them happens at huge doses"
X Link 2026-02-13T22:59Z 14.2K followers, [--] engagements
"GLP-1 drugs have long term success from studies. If you want weight loss - see someone who is actually board certified in obesity medicine - not a diet guru The harsh truth about long-term success on weight loss drugs. If you're looking for real guidance to improve your health long-term be sure to check out @reverohealth today. https://t.co/EE2aqkwwO2 The harsh truth about long-term success on weight loss drugs. If you're looking for real guidance to improve your health long-term be sure to check out @reverohealth today. https://t.co/EE2aqkwwO2"
X Link 2026-02-11T17:31Z 14.2K followers, [----] engagements
"The COVID response exposed failures of institutions not failures of science. That distinction matters. Science did what science does: it updated as evidence changed. Masks transmission dynamics boosters myocarditis riskthose corrections are a feature not a bug. What eroded trust was poor communication political overreach and officials speaking with unwarranted certaintynot some mythical Vaccine Industrial Complex. Layered on top of that was a well-funded coordinated anti-vaccine ecosystem that exploited every misstep. The same network that denied COVIDs existence pivoted seamlessly to"
X Link 2026-01-29T21:50Z 14.2K followers, 13.3K engagements
"Real food is adding tallow to french fries - to having your Superbowl spokesman be a convicted rapist who shames people who are obese This movement will not slow down. We are changing the incentives. We are restoring common sense. We are putting REAL FOOD back at the center of the American diet. Together we will Make America Healthy Again. This movement will not slow down. We are changing the incentives. We are restoring common sense. We are putting REAL FOOD back at the center of the American diet. Together we will Make America Healthy Again"
X Link 2026-02-13T17:41Z 14.2K followers, [----] engagements
"The claim that the chickenpox vaccine caused shingles epidemics is a resurrection of an old immune-boosting hypothesis that was modeled debated and then tested against decades of real-world data. Shingles rates were rising before vaccination have risen in countries without universal varicella programs and track far more cleanly with aging populations than with pediatric immunization schedules. Meanwhile childhood hospitalizations and deaths from varicella collapsed after vaccination. That is not a trade of one plague for another; it is disease prevention working exactly as intended. RFK JR -"
X Link 2026-02-13T21:10Z 14.2K followers, 14.3K engagements
"Obesity is not a moral parable about proper order or evil humors; it is a chronic relapsing biologically mediated disease characterized by dysregulated energy balance neurohormonal signaling and adipose tissue dysfunction. Yes lifestyle interventions can dramatically improve metabolic health and I prescribe them daily but the fact that behavior influences a disease does not make it optional or philosophical. Hypertension improves with sodium restriction; type [--] diabetes improves with weight loss; coronary disease improves with exercise yet none cease to be diseases. The danger in framing"
X Link 2026-02-13T21:21Z 14.2K followers, [----] engagements
"Statins save lives and every drug from antibiotics to statins are studied - so be contrarian but be honest Crestor and all statins are cellular poisons that block the crucial mevalonate pathway. Harms greatly exceed the minuscule or imaginary benefit. @Marion436842126 Crestor and all statins are cellular poisons that block the crucial mevalonate pathway. Harms greatly exceed the minuscule or imaginary benefit. @Marion436842126"
X Link 2026-02-14T01:49Z 14.2K followers, [----] engagements
"Yes ivermectin nonsense is sweeping the globe with anecdotes that make Paul Bunyan seem like a midget IVERMECTIN CANCER Revolution is sweeping the Globe 😃 Ivermectin Fenbendazole Mebendazole are the future of Cancer Care. Nothing else comes remotely close to the potential for helping millions of cancer patients 😉 IVERMECTIN CANCER Revolution is sweeping the Globe 😃 Ivermectin Fenbendazole Mebendazole are the future of Cancer Care. Nothing else comes remotely close to the potential for helping millions of cancer patients 😉"
X Link 2026-02-14T01:50Z 14.2K followers, [----] engagements
"During the major COVID waves hospitals across the country canceled elective surgeries delayed cancer operations postponed joint replacements deferred cardiac procedures because beds ventilators and staff were consumed by COVID admissions. I lived that. Many of us did. ICUs were full. Recovery rooms became ICU overflow. Surgical wards became COVID units. Now ask the obvious question: What emptied those hospitals Not wishful thinking. Not podcasts. Not revisionist IFR math. Vaccination. After widespread vaccination severe cases and ICU admissions dropped dramatically relative to prior waves"
X Link 2026-02-14T16:03Z 14.2K followers, 42.5K engagements
"Sorry - you may think it is a lie but it is not and administrators cannot empty a hospital that is a doctor who can discharge a patient. And since I was there and you were not- you are just a conspiracy nut spreading nonsense @drterrysimpson This is a lie. The hospitals were emptied because administrators emptied them because they were told to. They were not full of COVID admissions at all. In Australia COVID cases went up 100x AFTER the vaccine rollout from [------] to [--------]. Deaths went up 20x https://t.co/THpehuXRtI @drterrysimpson This is a lie. The hospitals were emptied because"
X Link 2026-02-14T22:48Z 14.2K followers, [----] engagements
"Mikes claim sounds tidy but its wrong. If eating the same number of calories were all Ozempic did the STEP trials wouldnt exist. Heres what the data actually show: Semaglutide causes more weight loss than calorie restriction alone. In STEP [--] both groups were prescribed a reduced-calorie diet and physical activity. Semaglutide: 14.9% body weight Placebo (same calorie advice): 2.4% That 12.5% difference is the drug effect not willpower. Pair-feeding studies settle this directly. When animals on semaglutide are fed the same number of calories as controls they still lose more weight and more fat"
X Link 2026-02-09T21:16Z 14.2K followers, 208.3K engagements
"The ketogenic diet was not suppressed. It fell out of favor because anti-epileptic drugs were easier to administer and worked for many patients without the dietary burden. And importantly: keto is still recommended particularly for refractory pediatric epilepsy. Centers like Mayo Clinic and Johns Hopkins Medicine actively run ketogenic programs today. But no side effects is simply incorrect. Ketogenic therapy can cause kidney stones micronutrient deficiencies constipation dyslipidemia slowed growth in children and requires close monitoring. Thats why its medically supervised. This isnt meat"
X Link 2026-02-13T18:10Z 14.2K followers, 21.5K engagements
"Tell me you don't understand biochemistry without telling me. @LauraLoomer @KassyAkiva Do you know the long term implications of facial filler which migrates and does not dissolve And Botox which paralyzes essential musculature for years Do you wonder where that Botox might go- say- into your lymph nodes @LauraLoomer @KassyAkiva Do you know the long term implications of facial filler which migrates and does not dissolve And Botox which paralyzes essential musculature for years Do you wonder where that Botox might go- say- into your lymph nodes"
X Link 2026-02-13T21:17Z 14.2K followers, [----] engagements
"Oh stop playing with statistics. That claim flips risk reduction on its head. Heres the reality: Most people statin or not will not have a heart attack in the next [---] years. Thats how population risk works. The question isnt Would everyone have had an MI without a statin The question is: Does lowering LDL with statins reduce events compared with not lowering it Yes. Repeatedly. In primary and secondary prevention. What the trials actually show In high-risk patients statins reduce major cardiovascular events by 2030% per mmol/L LDL reduction. In secondary prevention (people who already had an"
X Link 2026-02-14T02:26Z 14.2K followers, [----] engagements
"This is recycled mythology dressed up as revelation. First: polio did not disappear when DDT spraying declined. DDT use in the U.S. peaked in the 1950s. Paralytic polio epidemics peaked in [----]. What followed the sharp sustained collapse in polio cases was the introduction of the inactivated polio vaccine in [----] and the oral vaccine in the early 1960s. Correlation is not causation especially when the timeline is wrong. Second: yes 9599% of poliovirus infections are asymptomatic. That has been known for decades. Its in every epidemiology textbook. That fact doesnt weaken the vaccine argument"
X Link 2026-02-14T15:20Z 14.2K followers, 10.6K engagements
"The Federal government has granted South Carolina [---] million to assist in the measles outbreak. But what if those people would have been vaccinated instead: MMR vaccine cost (public sector pricing): Vaccine itself: $20$25 per dose Two doses required: $40$50 Add administration costs (nursing supplies logistics): $20$30 per dose So a fully vaccinated person costs roughly $70$100 total. If [---] people had been fully vaccinated: Low estimate: [---] $70 = $63000 High estimate: [---] $100 = $90000 The federal measles response funding: $1.4 million Even at the high estimate vaccinating those [---] people"
X Link 2026-02-14T15:39Z 14.2K followers, [----] engagements
"Incorrect. Food quality does not allow someone to lose weight. It is a nice story and we advocate for healthy foods like the Mediterranean diet - but that is not how one can lose weight. Yes UPF is easier to increase calories but obesity is not food choice or willpower it is a disease The secret to fat loss Food quality counting calories https://t.co/8oYisnicX4 The secret to fat loss Food quality counting calories https://t.co/8oYisnicX4"
X Link 2026-02-08T16:20Z 14.2K followers, 12.7K engagements
"It is clear that GLP-1 are a danger to the health and life coaches and diet demagogues. They work quite well - but the amount of resistance from people who want to defend their turf is extraordinary"
X Link 2026-02-10T16:35Z 14.2K followers, 40.4K engagements
"What happened in that debate was not science. It was rhetorical theater. He redefined causation to mean deterministic laboratory proof in humans a standard that cannot be met for any chronic disease. Not hypertension. Not diabetes. Not smoking. Not heart disease. Having set an impossible bar he then declared victory when it wasnt met. He redefined risk as metaphysical certainty. He dismissed adjusted epidemiology as fabrication. He called convergent evidence theology. He rejected Mendelian randomization because it wasnt perfect. This is not skepticism. It is definitional sabotage. Medicine"
X Link 2026-02-12T15:59Z 14.2K followers, [----] engagements
"@CoachBigBri Some cannot and if we just have whole food we will not be able to have enough or store enough to feed the planet not even enough to feed the US"
X Link 2026-02-13T17:32Z 14.2K followers, [---] engagements
"Yes we can call you anti-vax - and rather silly for not knowing the difference between ethyl mercury and methyl mercury - well you do but that does not fit the narrative -- your antivax narrative RFK Jr.: I spent [--] years trying to get mercury out of the fish in this country and nobody ever called me anti-fish." https://t.co/Of9PziJ2rx RFK Jr.: I spent [--] years trying to get mercury out of the fish in this country and nobody ever called me anti-fish." https://t.co/Of9PziJ2rx"
X Link 2026-02-13T17:42Z 14.2K followers, 15K engagements
"If you have a loved one in the hospital let them rest - dont stay more then ten or twenty minutes - I was in the ICU for five days - trust me youre keeping them up and youre not helping the staff do their job Genuine bit of advice: If you have a close relative over the age of [--] in the hospital and you love them DO NOT leave them alone. Be there every moment that you are allowed to be there watching over things as a solid advocate. Genuine bit of advice: If you have a close relative over the age of [--] in the hospital and you love them DO NOT leave them alone. Be there every moment that you"
X Link 2026-02-14T01:53Z 14.2K followers, 11.4K engagements
"He invokes leucine like a priest invoking Latin mystical threshold sacred number metabolic incantation and just as the congregation begins to worry their breakfast is heresy behold: salvation arrives in the form of his own powdered sacrament. It is remarkable how often the crisis in modern physiology can be resolved by entering ones credit card number. Nothing is a "high protein" meal if it does not eclipse the leucine threshold for muscle protein synthesis 2.5g. You would need [--] eggs to achieve this 4.5oz of steak chicken or fish 30g of whey protein [--] cups greek yogurt and far more plant"
X Link 2026-02-14T02:29Z 14.2K followers, [----] engagements
"Chanting saturated fat is healthy four times does not transmute a review article into a randomized trial demonstrating benefit. The cited paper argues there is no clear association in selected data. It does not show improved outcomes. It does not overturn LDL biology. It does not invalidate decades of mechanistic genetic epidemiologic and interventional evidence. And even within the observational literature saturated fat from dairy does not behave the same as saturated fat from processed meat so slogans are already scientifically illiterate. Not conclusively harmful is not the same thing as"
X Link 2026-02-14T21:15Z 14.2K followers, [----] engagements
"@KerryOLeary4 Not at all - I was there - and so were my colleagues"
X Link 2026-02-14T23:49Z 14.2K followers, [---] engagements
"Lowering drug prices is good policy. Period. But lets be precise. The Most Favored Nation (MFN) rule was proposed near the end of the Trump administration to tie certain Medicare drug prices to prices paid in other countries. It faced legal challenges and was never fully implemented before being rescinded. Ozempics list price in the U.S. did not universally drop from $1200 to $400 because of MFN. Price reductions and discounts were seeing now are largely the result of manufacturer adjustments negotiations with PBMs insurance coverage expansion and competitive pressure in the GLP-1 market. If"
X Link 2026-02-15T01:07Z 14.2K followers, [---] engagements
"That screenshot shows a manufacturer savings program not a federal price control. The $199 starter dose price is a coupon-based promotional offer through Novo Nordisk not a permanent list price reduction and not proof of a tariff-induced structural change. These programs are common in the U.S. pharmaceutical market and are typically limited to: Certain doses Certain insurance statuses A defined time period The list price remains around $1000+. The savings is the manufacturer absorbing part of the cost temporarily to expand market share and compete in a rapidly growing GLP-1 space. The Most"
X Link 2026-02-15T01:27Z 14.2K followers, [---] engagements
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/creator/twitter::drterrysimpson