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# ![@davidasinclair Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::520445177.png) @davidasinclair David Sinclair

David Sinclair posts on X about ozempic, sauna, tre, dna the most. They currently have XXXXXXX followers and XXX posts still getting attention that total XXXXXXX engagements in the last XX hours.

### Engagements: XXXXXXX [#](/creator/twitter::520445177/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::520445177/c:line/m:interactions.svg)

- X Week XXXXXXXXX +384%
- X Month XXXXXXXXX +105%
- X Months XXXXXXXXXX +206%
- X Year XXXXXXXXXX +259%

### Mentions: XX [#](/creator/twitter::520445177/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::520445177/c:line/m:posts_active.svg)

- X Months XXX +15%
- X Year XXX +346%

### Followers: XXXXXXX [#](/creator/twitter::520445177/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::520445177/c:line/m:followers.svg)

- X Week XXXXXXX +0.54%
- X Month XXXXXXX +1.10%
- X Months XXXXXXX +5%
- X Year XXXXXXX +10%

### CreatorRank: XXXXXXX [#](/creator/twitter::520445177/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::520445177/c:line/m:influencer_rank.svg)

### Social Influence [#](/creator/twitter::520445177/influence)
---

**Social category influence**
[stocks](/list/stocks)  [technology brands](/list/technology-brands)  [exchanges](/list/exchanges)  [finance](/list/finance) 

**Social topic influence**
[ozempic](/topic/ozempic) #97, [sauna](/topic/sauna) #6, [tre](/topic/tre), [dna](/topic/dna), [bmi](/topic/bmi), [$30m](/topic/$30m), [$googl](/topic/$googl), [$atai](/topic/$atai), [nasdaq](/topic/nasdaq), [marks](/topic/marks)

**Top assets mentioned**
[Alphabet Inc Class A (GOOGL)](/topic/$googl) [ATAI Life Sciences (ATAI)](/topic/$atai)
### Top Social Posts [#](/creator/twitter::520445177/posts)
---
Top posts by engagements in the last XX hours

"Good point. Same animist thinking fuels skepticism about longevity interventions"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1941627246839472198) 2025-07-05 22:36:23 UTC 493.2K followers, 54.5K engagements


"NEW STUDY: It's dogma that fasting is good for you because it increases autophagy the recycling of cell parts. But in the largest study ever 6months of time-restricted eating (TRE) or calorie restriction (CR) did not increase autophagy Huh Is fasting still worth it . 🧵"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1921321762559521208) 2025-05-10 21:49:39 UTC 493.2K followers, 1.1M engagements


"AI allows us to do centuries of research a day and my PhD thesis in minutes"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1939547496667398432) 2025-06-30 04:52:12 UTC 493.2K followers, 108.5K engagements


"High-sensitivity CRP XXX mg/L doubles the risk of heart attack. Ridker et al. NEJM (my cardiologist)"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1945439105984188669) 2025-07-16 11:03:22 UTC 493.2K followers, 82.5K engagements


"People with low grip strength have up to X higher mortality risk Lancet 2015"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1945848295038791889) 2025-07-17 14:09:20 UTC 493.2K followers, 49.1K engagements


"New study of XXX participants confirms that a diet high in omega-3 fatty acids & low in omega-6 linoleic acid reduces the frequency and intensity of headaches 💊🐟"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940436514540003584) 2025-07-02 15:44:51 UTC 493.2K followers, 69.6K engagements


"Betaine is not new. Also known as trimethylglycine or TMG sometimes taken with NMN was discovered in 1806 by German chemist Andreas Marggraf in sugar beets - hence the name"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1941155549447663774) 2025-07-04 15:22:02 UTC 493.2K followers, 85.6K engagements


"Researcher's showed the enzyme that breaks down lactate is enriched in quiescent (resting) HFSCs"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795951557578993) 2025-07-03 15:33:07 UTC 493.1K followers, 19.7K engagements


"Their latest work on hair loss in mice implicates a molecule produced during metabolism called lactate"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795945740128394) 2025-07-03 15:33:06 UTC 492.9K followers, 20.4K engagements


"Walking 8000 steps/day cuts the risk of dying in the next decade by half"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1943312037481758887) 2025-07-10 14:11:09 UTC 493.2K followers, 278.6K engagements


"Fasting for 14+ hours activates autophagyyour bodys cleanup mechanism"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1943700148317528398) 2025-07-11 15:53:22 UTC 493.2K followers, 368.7K engagements


"Move like your life depends on it - because it does"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1941102986320617912) 2025-07-04 11:53:10 UTC 493.2K followers, 49.9K engagements


"NEW PAPER: DNA methylation entropy is proportional to chronological age supporting the Information Theory of Aging the concept that our bodies are biological computers running on software that becomes corrupted over time but can be"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1911746319963553840) 2025-04-14 11:40:15 UTC 493.2K followers, 234.9K engagements


"Broke a rule by eating a snack bar before bed. It completely messed up my glucose & I woke up feeling ill. Wont do that again ❌"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1935327450621227335) 2025-06-18 13:23:15 UTC 493.2K followers, 1.1M engagements


"What is lactate During anaerobic exercise the body breaks down liver glycogen to produce energy which generates a byproduct called pyruvate. In the presence of adequate oxygen pyruvate is converted into acetyl-CoA"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795959493181747) 2025-07-03 15:33:09 UTC 493.2K followers, 86.2K engagements


"5 minutes in a sauna 4x/week reduces cardiovascular risk by 50%"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1945129098335936750) 2025-07-15 14:31:30 UTC 493.2K followers, 3.6M engagements


"9 out of XX people will die from age-related diseases - so lets work on the universal cause: aging"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1944046414603989182) 2025-07-12 14:49:18 UTC 493.2K followers, 99.6K engagements


"NEW STUDY: People who consistently do vigorous exercise have slower rates of epigenetic aging compared to those who don't. Light to medium activities don't cut it"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1923211972834726343) 2025-05-16 03:00:40 UTC 493.2K followers, 768.9K engagements


"NEW STUDY: SIRT1 the NAD-dependent longevity enzyme is normally found in the cell's nucleus. Circulating SIRT1 modifies PCSK9 to promote LDL cholesterol uptake into the liver & reduce plaque in mice. Consistent with this people with high levels of circulating SIRT1 have fewer deaths from cardiovascular causes"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1944782052756168783) 2025-07-14 15:32:28 UTC 493.2K followers, 63.8K engagements


"Misinformation & clickbait must end @AOL X. Our study was of chemical cocktails not a new drug X. Was tested only on cells X. Was published in 2023"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1941136541285245104) 2025-07-04 14:06:30 UTC 493.2K followers, 30.9K engagements


"While the exact formula of PP405 is not discosed possibilities are it is: X. Lactate or a lactate precursor X. An inhibitor of the mito pyruvate carrier similar to UK-5099 X. An inhibitor of lactate dehydrogenase"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795964350255539) 2025-07-03 15:33:10 UTC 493.2K followers, 33.2K engagements


"When oxygen is limited pyruvate is converted into lactate which allows the body to continue producing energy through anaerobic metabolism and is thought to cause some of the muscle burn felt during exercise"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795961238081943) 2025-07-03 15:33:10 UTC 493.2K followers, 68.9K engagements


"NEW STUDY: Ocampo Lab publishes reprogramming cocktails that reduce DNA damage & extend lifespan of worms up to 42%. The race is on to test them in humans 🚀"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940427510631838016) 2025-07-02 15:09:04 UTC 493.2K followers, 96.7K engagements


"Muscle mass predicts lifespan better than BMI or weight - so get moving and get lifting"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1944724110044471760) 2025-07-14 11:42:13 UTC 493.2K followers, 754.1K engagements


"NEW REVIEW: Targeting the hallmarks of aging: mechanisms and therapeutic opportunities"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1945508546126238099) 2025-07-16 15:39:17 UTC 493.2K followers, 30.5K engagements


"The ability of the hair follicle to maintain this cycle depends on the presence of the hair follicle stem cells (HFSC) which reside in the follicle's bulge at the base"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795950047678496) 2025-07-03 15:33:07 UTC 493.1K followers, 19.9K engagements


"Pelage was founded on the work of Dr. William Lowry at UCLA and backed by Google Ventures who have led two rounds totalling $30M"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795941365366901) 2025-07-03 15:33:05 UTC 493.1K followers, 21.2K engagements


"Our lab's funding was terminatedheres how that compares to the amount of all terminated research at @harvardmed"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1937510924337737889) 2025-06-24 13:59:36 UTC 493.1K followers, 150.5K engagements


"@C_Angermayer @atai_life @BeckleyPsytech Congrats my friend 👏"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1929590384952299846) 2025-06-02 17:26:12 UTC 493.1K followers, XXX engagements


"You dont slow down because you age. You age because you slow down"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1941463649630982620) 2025-07-05 11:46:19 UTC 493.2K followers, 190.2K engagements


"Recent news claimed scientists at UCLA had solved hair loss. Is this true Let's dive in 🧵"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795933752807843) 2025-07-03 15:33:03 UTC 493.2K followers, 249.1K engagements


"Longevity is earned in the gym the sauna and the kitchen"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1944352438510653778) 2025-07-13 11:05:20 UTC 493.2K followers, 403.3K engagements


"The human hair follicle undergoes cyclical rounds of rest (telogen) regeneration (anagen) and degeneration (catagen)"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795948520899012) 2025-07-03 15:33:07 UTC 493.1K followers, 19.8K engagements


"NEW STUDY: Researchers measured levels of eight cytokines in over 1000 people living in non-industrial societies and conclude that inflammation is not an inexorable part of aging"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1941134038062027100) 2025-07-04 13:56:33 UTC 493.2K followers, 75.1K engagements


"Thus lactate itself promotes hair growth So what is lactate"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1940795957853278433) 2025-07-03 15:33:09 UTC 493.1K followers, 20.5K engagements


"Only XX% of lifespan is genetic. The rest is up to you"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1942589626394304843) 2025-07-08 14:20:33 UTC 493.2K followers, 184.7K engagements


"NEW: In tea onion & celery the flavonoid apigenin inhibits the NAD-destroying enyzme CD38 & prevents muscle loss in obese rats by upping the anabolic enzyme p70S6K💪 Ozempic adjunct💉🧵"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1944801485511905429) 2025-07-14 16:49:41 UTC 493.2K followers, 55.9K engagements


"Congrats my friend. Exciting news in the psychedelic medicine space Pleased to be a backer @atai_life"  
![@davidasinclair Avatar](https://lunarcrush.com/gi/w:16/cr:twitter::520445177.png) [@davidasinclair](/creator/x/davidasinclair) on [X](/post/tweet/1929590339695685665) 2025-06-02 17:26:01 UTC 493.2K followers, 34.7K engagements