# ![@austinvrabel Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::786833096259670017.png) @austinvrabel Austin Vrabel, CFA

Austin Vrabel, CFA posts on X about $cadl, in the, ceo, this is the most. They currently have [-----] followers and [--] posts still getting attention that total [---] engagements in the last [--] hours.

### Engagements: [---] [#](/creator/twitter::786833096259670017/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::786833096259670017/c:line/m:interactions.svg)

- [--] Month [---] +64,300%
- [--] Months [------] +39%
- [--] Year [------] +7,793%

### Mentions: [--] [#](/creator/twitter::786833096259670017/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::786833096259670017/c:line/m:posts_active.svg)

- [--] Months [--] +150%
- [--] Year [--] +2,550%

### Followers: [-----] [#](/creator/twitter::786833096259670017/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::786833096259670017/c:line/m:followers.svg)

- [--] Month [---] -1.30%
- [--] Months [---] +33%
- [--] Year [---] +274%

### CreatorRank: undefined [#](/creator/twitter::786833096259670017/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::786833096259670017/c:line/m:influencer_rank.svg)

### Social Influence

**Social category influence**
[stocks](/list/stocks)  [finance](/list/finance)  [celebrities](/list/celebrities)  [automotive brands](/list/automotive-brands)  [technology brands](/list/technology-brands)  [financial services](/list/financial-services) 

**Social topic influence**
[$cadl](/topic/$cadl) #9, [in the](/topic/in-the), [ceo](/topic/ceo), [this is](/topic/this-is), [study](/topic/study), [we are](/topic/we-are), [approved](/topic/approved), [has been](/topic/has-been), [deep](/topic/deep), [lab](/topic/lab)

**Top accounts mentioned or mentioned by**
[@paulpetertak](/creator/undefined) [@ideapharma](/creator/undefined) [@cleareyecapital](/creator/undefined) [@bwalkerttaggg](/creator/undefined) [@martinshkreli](/creator/undefined) [@candeltx](/creator/undefined) [@routeco145](/creator/undefined) [@biotech2k1](/creator/undefined) [@patriots](/creator/undefined) [@coachvrabel50](/creator/undefined) [@stephensinc](/creator/undefined) [@adamfeuerstein](/creator/undefined) [@tmz](/creator/undefined) [@enews](/creator/undefined) [@apexonco](/creator/undefined) [@oshea9harry](/creator/undefined) [@hopkinsmedicine](/creator/undefined) [@aghazimd](/creator/undefined) [@bradloncar](/creator/undefined) [@alienhocke16905](/creator/undefined)

**Top assets mentioned**
[Candel Therapeutics, Inc. (CADL)](/topic/$cadl) [Summit Therapeutics Inc. Common Stock (SMMT)](/topic/$smmt) [Nuvation Bio Inc. (NUVB)](/topic/$nuvb)
### Top Social Posts
Top posts by engagements in the last [--] hours

"@paulpetertak @cleareyecapital @BWalkerTTAGGG @MartinShkreli @paulpetertak haha no he rubs a lot of people the wrong way. I think hes smart but his downfall is hes arrogant. His due diligence was reading headlines and just saying that the drug was stupid"  
[X Link](https://x.com/austinvrabel/status/1866691066067554639)  2024-12-11T03:46Z [--] followers, [---] engagements


"@MartinShkreli @BWalkerTTAGGG @paulpetertak @cleareyecapital Haha Just pointing out that they have some compelling data so far. Several drugs in the pipeline and phase [--] & phase [--] prostate being released this month. Only $164M market cap. Dig into it and let us know your thoughts. We respect your opinion"  
[X Link](https://x.com/austinvrabel/status/1866717285169398125)  2024-12-11T05:30Z [--] followers, [---] engagements


"@adamfeuerstein So I guess $SMMT drugs dont work either What an arrogant comment https://youtu.be/AjPcXissLmUsi=qHGYCNomr6Fe5-9L https://youtu.be/AjPcXissLmUsi=qHGYCNomr6Fe5-9L"  
[X Link](https://x.com/austinvrabel/status/1900406812148720112)  2025-03-14T04:41Z [--] followers, [----] engagements


"Terrible news. Hoping he can have access to a medicine being explored at $CADL called CAN-3110 looking to treat patients with recurrent high-grade glioma. @paulpetertak @CandelTx @TMZ @enews https://www.usatoday.com/story/life/health-wellness/2025/04/30/michael-bolton-brain-cancer-glioblastoma/83365208007/ https://vimeo.com/822133681 https://www.usatoday.com/story/life/health-wellness/2025/04/30/michael-bolton-brain-cancer-glioblastoma/83365208007/ https://vimeo.com/822133681"  
[X Link](https://x.com/austinvrabel/status/1917644084648501321)  2025-04-30T18:15Z [--] followers, [--] engagements


"@RouteCO145 @paulpetertak @ideapharma Do you follow $NUVB They recently got FDA approval and the stock went down over 15% How is a company is a FDA approved asset less valuable than it was before Sometimes the stock market makes [--] sense. We need to be patient and trust mgmt to do everything they can to add value"  
[X Link](https://x.com/austinvrabel/status/1937188264286519716)  2025-06-23T16:37Z [---] followers, [---] engagements


"@RouteCO145 @paulpetertak @ideapharma In the case of NUVB mgmt recently went on to buy a huge amount of shares at the depressed price showing confidence and belief. I expect our team to do the same if they are able. IMO this is a table pounding buy at these levels"  
[X Link](https://x.com/austinvrabel/status/1937189963499733402)  2025-06-23T16:44Z [---] followers, [--] engagements


"@paulpetertak Tides are turning. Word is spreading. Value creation working Great work. Its the irony of investing stock was in 4s (joke) yet no one bought then as it climbs people start buying more All started with having ALL mgmt commit to those monster buys"  
[X Link](https://x.com/austinvrabel/status/1944893662997176774)  2025-07-14T22:55Z [---] followers, [--] engagements


"$CADL Dr. Paul Peter Taks comments Couldnt have said it any better I think this is a table pounding buy opportunity"  
[X Link](https://x.com/austinvrabel/status/1944913988397228222)  2025-07-15T00:16Z [---] followers, [---] engagements


"$CADL Excellent comments here from CADL CSO Dr. Francesca Barone of CADL in terms of Rolling BLA and CAN-3110 excitement later this year #bofa #bankofamerica #biotech #FDA #cancer #investing She did a great job for this short presentation"  
[X Link](https://x.com/austinvrabel/status/1944934336995954972)  2025-07-15T01:37Z [---] followers, [---] engagements


"$CADL NEW market Data out from CADL. I know they have been doing market research and the TAM of prostate has been updated They now see it as 11B + opportunity. The range is 10-16B in US ALONE"  
[X Link](https://x.com/austinvrabel/status/1945565586224025607)  2025-07-16T19:25Z [---] followers, [----] engagements


"$CADL Here is a nice stat. % of biotech companies with stat sig phase [--] trial - hit primary & secondary endpoints done under SPA go on to get FDA approval @paulpetertak CEO says its 92% in last video with @ideapharma. Looks spot on"  
[X Link](https://x.com/austinvrabel/status/1945690431456678074)  2025-07-17T03:42Z [---] followers, [----] engagements


"$REPL $CADL All eyes on REPL this week with PDUFA Tuesday July [--]. Viral immunotherapies have come a long way and think with the FDA nod its further validation the science is top tier. Also given the similarities between CADL and REPL MOA using HSV should only benefit CADL"  
[X Link](https://x.com/austinvrabel/status/1947072828353966377)  2025-07-20T23:15Z [---] followers, [----] engagements


"@Biotech2k1 $CADL Viral immunotherapy. Pipeline in a product for [--] assets CAN-2409 and CAN-3110. Huge unmet needs in all indications such as Early localized prostate cancer with recent stat sig Phase [--] data done under SPA. Phase [--] NSCLC after failing chemo & ICI. Pancreatic & HGG"  
[X Link](https://x.com/austinvrabel/status/1949114475962826952)  2025-07-26T14:27Z [---] followers, [---] engagements


"$CADL Have a great weekend everyone Long & strong. Giving a speech at my buddies wedding tomorrow. 🎤 hope to captivate the crowd with some good stories like PPT does on the big stage"  
[X Link](https://x.com/austinvrabel/status/1951393253447881065)  2025-08-01T21:23Z [---] followers, [---] engagements


"$CADL Great to hear from @paulpetertak today mgmt knows the clocks ticking & is full steam ahead. Enabling/protocol work has been underway. Has Type B meeting been completed for either yet Will you announce once done Very excited for CAN-3110 time in the sun next Quarter"  
[X Link](https://x.com/austinvrabel/status/1955785113129890296)  2025-08-14T00:14Z [---] followers, [---] engagements


"$CADL Awesome snippet of PPT talking about CAN-3110. Totally agree that new administration cares about gold standard OS as surrogate endpoint as opposed to ORR PFS for immunotherapies. You can game certain endpoints by single arm study and/ or combination therapies. OS is clean"  
[X Link](https://x.com/austinvrabel/status/1955793859834995010)  2025-08-14T00:49Z [---] followers, [---] engagements


"$CADL Very constructive EOP2 (End of Phase 2) meeting with FDA recently completed for patients who failed SOC ICI & chemo in NSCLC Great news in the enabling work being done to advance to large randomized potentially registrational Phase [--] clinical trial"  
[X Link](https://x.com/austinvrabel/status/1955808692215115948)  2025-08-14T01:48Z [---] followers, [---] engagements


"$CADL CAN-3110 in Recurrent Glioblastoma. Very interesting. From the paper published in Nature in 2023: HSV-1 seropositive mOS: [----] months HSV-1 seronegative mOS: [---] months p = [-----] Telling biomarker signal from CAN-3110"  
[X Link](https://x.com/austinvrabel/status/1956154610491777182)  2025-08-15T00:42Z [---] followers, [---] engagements


"$CADL Makes perfect sense that theyre now exploring multiple intratumoral injections (up to 6) for CAN-3110. The first dose could act as a primer helping HSV-1-negative patients develop immunity and potentially boosting anti-tumor effects. $CADL CAN-3110 in Recurrent Glioblastoma. Very interesting. From the paper published in Nature in 2023: HSV-1 seropositive mOS: [----] months HSV-1 seronegative mOS: [---] months p = [-----] Telling biomarker signal from CAN-3110 $CADL CAN-3110 in Recurrent Glioblastoma. Very interesting. From the paper published in Nature in 2023: HSV-1 seropositive mOS: 14.2"  
[X Link](https://x.com/austinvrabel/status/1956154810354344360)  2025-08-15T00:43Z [---] followers, [---] engagements


"@paulpetertak PGENs AdenoVerse (PRGN-2012) got FDA approval today. Always great to see another immunotherapy get approval. Different payload than CAN-2409 but same principle: non-replicating adenovirus driving immune activation"  
[X Link](https://x.com/austinvrabel/status/1956171141497938154)  2025-08-15T01:48Z [---] followers, [--] engagements


"$CADL 92% approval odds in prostate cancer. US TAM $11B. Even at a conservative 10% share thats $1.1B in annual sales. Applying a standard 23x revenue multiple implies a $23B market cap still nearly 8x todays valuation. Undervalued on any metric. Thats correct. Thats correct"  
[X Link](https://x.com/austinvrabel/status/1957137701335183414)  2025-08-17T17:49Z [---] followers, [---] engagements


"Part [--] $CADL remains on track for BLA submission in Q4 [----]. Progress includes scaling up commercial manufacturing completing [--] commercial runs and advancing assay development with close FDA alignment"  
[X Link](https://x.com/austinvrabel/status/1963379156634538220)  2025-09-03T23:10Z [---] followers, [---] engagements


"Part [--] $CADL A comparability study is set to begin in Q4 [----] with PPQ prep underway. Manufacturing has transitioned to SAFC (Merck-Millipore) expected to deliver a more efficient process vs. the Phase [--] legacy system positioning Candel for commercial supply. Part [--] $CADL remains on track for BLA submission in Q4 [----]. Progress includes scaling up commercial manufacturing completing [--] commercial runs and advancing assay development with close FDA alignment. Part [--] $CADL remains on track for BLA submission in Q4 [----]. Progress includes scaling up commercial manufacturing completing 3"  
[X Link](https://x.com/austinvrabel/status/1963379313564369142)  2025-09-03T23:11Z [---] followers, [---] engagements


"$CADL I transcribed the conversation between Citi Analyst Yigal Nochomovitz and CEO PPT highlighting some of my fav parts of the chat. This answers WHY DFS matters in localized prostate cancer and provides a CMC/manufacturing update & much more. https://drive.google.com/file/d/1jO8LY2XmplkgSNR6-SDR4eKlxWZDwAg5/viewusp=sharing https://drive.google.com/file/d/1jO8LY2XmplkgSNR6-SDR4eKlxWZDwAg5/viewusp=sharing"  
[X Link](https://x.com/austinvrabel/status/1963453486634328224)  2025-09-04T04:06Z [---] followers, [---] engagements


"$CADL Everything you need to know on DFS and what is categorized as an Event. Biopsy is the BEST way to detect any signs of cancer. Could not be spelled out any more clear then this. I would have highlighted the whole thing but kept second page blank for easier reading"  
[X Link](https://x.com/austinvrabel/status/1963609011665998016)  2025-09-04T14:24Z [---] followers, [---] engagements


"$CADL Impressive to get so many things wrong in one report by Jacob Plieth from @ApexOnco . [--]. The name of CAN-2409 is aglatimagene besadenovec not agla-vec. [--]. The data of the phase 2a clinical trial of CAN-240 in NSCLC has never disappointed. They are in fact very encouraging Impressive to get so many things wrong in one report by Jacob Plieth from @ApexOnco . [--]. The name of CAN-2409 is aglatimagene besadenovec not agla-vec. [--]. The data of the phase 2a clinical trial of CAN-240 in NSCLC has never disappointed. They are in fact very encouraging"  
[X Link](https://x.com/austinvrabel/status/1965898177191751923)  2025-09-10T22:00Z [---] followers, [---] engagements


"$CADL Target audience at #ASTRO25 congress attendees including an audience of radiation oncologists medical oncologists APPs nurses and pharmacists involved in the diagnosis and management of patients with prostate cancer. Attending #ASTRO25 Dr. Gejerman will present our phase [--] prostate cancer study. The data represents potential progress for 65k men diagnosed annually with intermediate-to-high-risk localized prostate cancer who undergo radiotherapy with curative intent. https://t.co/OpRlzLEUNk https://t.co/r1660AiVhI Attending #ASTRO25 Dr. Gejerman will present our phase [--] prostate cancer"  
[X Link](https://x.com/austinvrabel/status/1968293927439712753)  2025-09-17T12:40Z [---] followers, [---] engagements


"$CADL Alright. [--] trading days left of Q3. Almost in Q4. Which means couple things: (see comments)"  
[X Link](https://x.com/austinvrabel/status/1968830008467554691)  2025-09-19T00:10Z [---] followers, [---] engagements


"5) Comparability study starting in Q4 in regards to CMC for CAN-2409. Based on new Manufacturing SAFC Merck Millipore. In the lab. Routine stuff. Small study based on everything FDA wants to see"  
[X Link](https://x.com/austinvrabel/status/1968831623635390709)  2025-09-19T00:16Z [---] followers, [--] engagements


"$CADL Alright some Friday Fun everyone comment what they think optimal dose will be for rHGG in arm C for CAN-3110. I am going with 3"  
[X Link](https://x.com/austinvrabel/status/1969178114765787206)  2025-09-19T23:13Z [---] followers, [---] engagements


"@Biotech2k1 $CADL . Opportunity there is INSANE. Early localized prostate. Its wide open. 65k in US alone will undergo radiotherapy. Option [--] is radiotherapy + CAN-2409. Reduced recurrence by 38% If approved likely charge $175k for CAN-2409"  
[X Link](https://x.com/austinvrabel/status/1973537400736588018)  2025-10-01T23:55Z [---] followers, [---] engagements


"@paulpetertak @oshea9_harry This all sounds awesome Dr. Tak The consistency across biomarkers is very encouraging. Totally agree that emphasizing completion of both administrations will be key. Likely helps reduce dropouts and strengthen the overall efficacy signal"  
[X Link](https://x.com/austinvrabel/status/1978666440493252734)  2025-10-16T03:36Z [---] followers, [---] engagements


"@Patriots @Patriots @CoachVrabel50 plz reach out to @paulpetertak on Prostate cancer treatment He may be able to help. He is CEO of company called Candel Therapeutics TOP in class early localized prostate cancer drug coming to market soon. They are located in Needham. Not far away"  
[X Link](https://x.com/austinvrabel/status/1971701714505158719)  2025-09-26T22:21Z [---] followers, [---] engagements


"$CADL in regards to Mechanistic study of CAN-2409 in localized prostate cancer. This is just lab work deep immunologic Biomarker data FDA wants to support BLA. Data in Q3 2026"  
[X Link](https://x.com/anyuser/status/1989047081970069921)  2025-11-13T19:05Z [---] followers, [----] engagements


"$CADL More on what is a SPA special protocol assessment with the FDA. Why it is used. CADL phase [--] early localized Prostate Cancer. It convincingly hit all primary and secondary endpoints agreed upon with the FDA"  
[X Link](https://x.com/austinvrabel/status/1963610990412730597)  2025-09-04T14:31Z [---] followers, [---] engagements


"$CADL EnLIGHTEN program. @paulpetertak seems very excited about all especially #2 - Holy Grail of immuno-Oncology 1) Alpha [---] - macro [---] targeting the CD47/SIRP pathway 2) TLSinducing multimodal immunotherapy 3) multimodal candidate encoding IL12 and IL15"  
[X Link](https://x.com/austinvrabel/status/1965221593510199377)  2025-09-09T01:11Z [---] followers, [---] engagements


"Totally agree. Ive always questioned the unknown ever since I was a kid. Its why companies like $CADL are so important to help people live longer with terrible cancers. We need technology to help us live longer. Hoping AI will help take us there We cannot understand the true nature of the Universe unless we question deeply. I want to know what is real even if the answer is total obliteration of my consciousness. We cannot understand the true nature of the Universe unless we question deeply. I want to know what is real even if the answer is total obliteration of my consciousness"  
[X Link](https://x.com/austinvrabel/status/1965222151038120034)  2025-09-09T01:14Z [---] followers, [---] engagements


"$CADL DFS endpoint is key in adjuvant setting where OS takes years to read out. I made a chart comparing DFS HR vs approved drugs. CADLs secondary endpoint is Prostate-Specific DFSso only events tied to prostate cancer count not unrelated deaths like heart attacks or accidents"  
[X Link](https://x.com/austinvrabel/status/1965809046847672387)  2025-09-10T16:06Z [---] followers, [---] engagements


"$CADL There are NO issues on the SPA with FDA. This is from latest 10-Q ( Q2 2025). "The comments about the SPA are also completely wrong and misleading as Candel has strictly adhered to the agreement with the FDA and the SPA is intact" From $CADL [--] Nov [----] SEC filing (8/8) https://t.co/jaovRYOQZA "The comments about the SPA are also completely wrong and misleading as Candel has strictly adhered to the agreement with the FDA and the SPA is intact" From $CADL [--] Nov [----] SEC filing (8/8) https://t.co/jaovRYOQZA"  
[X Link](https://x.com/austinvrabel/status/1966155963678994954)  2025-09-11T15:04Z [---] followers, [---] engagements


"$CADL Weekend reflections"  
[X Link](https://x.com/austinvrabel/status/1967420056423505991)  2025-09-15T02:47Z [---] followers, [---] engagements


"$CADL Has there ever been a company ever to receive the RMAT designation based on their phase [--] data that did not receive FDA approval Besides any CMC or manufacturing issues Answer: NO We just need to nail that section of BLA "  
[X Link](https://x.com/austinvrabel/status/1967625570440905017)  2025-09-15T16:24Z [---] followers, [---] engagements


"$CADL Head of M&A at Gilead on biotech deals: Has this company solved a key problem Have they come up with something that can be first-in-class or best-in-class and ideally both CADL is 1st & only in class for early localized prostate cancer"  
[X Link](https://x.com/austinvrabel/status/1968138925500969105)  2025-09-17T02:24Z [---] followers, [---] engagements


"$CADL I put together this decision tree for patients. So why in the world would people choose option [--] over option [--] Option [--] is a CLEAR winner as opposed to option [--]. I see adoption and market share % very high. Also any ADT in combo with option [--] has serious side effects"  
[X Link](https://x.com/austinvrabel/status/1969868306040713584)  2025-09-21T20:56Z [---] followers, [---] engagements


"$CADL I wouldnt t be surprised to see an announcement that we will be at ESMO in October. #berlin #ESMO25"  
[X Link](https://x.com/austinvrabel/status/1970617079608025347)  2025-09-23T22:31Z [---] followers, [---] engagements


"$CADL Option [--]. CLEAR winner. If you want your Willy to still work & have a happy wife (happy life) choose CAN-2409 See comments for more description"  
[X Link](https://x.com/austinvrabel/status/1970832994723344531)  2025-09-24T12:49Z [---] followers, [---] engagements


"$CADL Hmmm which one are you picking CAN-2409 also reduces recurrence by 30-38% over radiotherapy alone which comes with use of ADT $CADL Option [--]. CLEAR winner. If you want your Willy to still work & have a happy wife (happy life) choose CAN-2409 See comments for more description https://t.co/pkJ6mVqrFR $CADL Option [--]. CLEAR winner. If you want your Willy to still work & have a happy wife (happy life) choose CAN-2409 See comments for more description https://t.co/pkJ6mVqrFR"  
[X Link](https://x.com/austinvrabel/status/1970834460338978830)  2025-09-24T12:55Z [---] followers, [---] engagements


"$CADL Awesome article Reminds me of CAN-2409 and Candel. "When Pharmacyclics released its first data in December [----] for a drug named PCI-32765 it did not generate much excitement. Most doctors and scientists ignored it." https://www.forbes.com/sites/nathanvardi/2023/01/13/for-blood-and-money-book-excerpt-wayne-rothbaum-pharmacyclics-robert-duggan/ https://www.forbes.com/sites/nathanvardi/2023/01/13/for-blood-and-money-book-excerpt-wayne-rothbaum-pharmacyclics-robert-duggan/"  
[X Link](https://x.com/austinvrabel/status/1970869270977654909)  2025-09-24T15:13Z [---] followers, [---] engagements


"$CADL This is like Pancreatic and NSCLC data $CADL Awesome article Reminds me of CAN-2409 and Candel. "When Pharmacyclics released its first data in December [----] for a drug named PCI-32765 it did not generate much excitement. Most doctors and scientists ignored it." https://t.co/POYOlJS760 $CADL Awesome article Reminds me of CAN-2409 and Candel. "When Pharmacyclics released its first data in December [----] for a drug named PCI-32765 it did not generate much excitement. Most doctors and scientists ignored it." https://t.co/POYOlJS760"  
[X Link](https://x.com/austinvrabel/status/1970871144585818596)  2025-09-24T15:21Z [---] followers, [---] engagements


"$CADL Early localized prostate cancer is WIDE open Blockbuster drug coming. CAN-2409 create new markets where youre the only player create new markets where youre the only player"  
[X Link](https://x.com/austinvrabel/status/1971696271493849524)  2025-09-26T21:59Z [---] followers, [---] engagements


"$CADL I have a fairly conservative $64 price target by [----]. Current stock price $5.5. Lot of assumptions in my model. Happy to discuss with anyone interested. Another very successful week. Everything on track. Enjoy the weekend $CADL Another very successful week. Everything on track. Enjoy the weekend $CADL"  
[X Link](https://x.com/austinvrabel/status/1971697454581272797)  2025-09-26T22:04Z [---] followers, [---] engagements


"$CADL Innovation is the key to extending patients lives. CAN-2409 in doing exactly that in Early localized intermediate/ high risk prostate cancer patients Dr. Patrick Walsh pioneered urologic discovery at @hopkinsmedicine for [--] years. @aghazimd and team celebrate this legacy of innovation and detail whats on the horizon for #personalizedmedicine in #urology. Learn more about Dr. Walshs impact at https://t.co/p0DMV8NLP4. https://t.co/R8e6vB6hYe Dr. Patrick Walsh pioneered urologic discovery at @hopkinsmedicine for [--] years. @aghazimd and team celebrate this legacy of innovation and detail"  
[X Link](https://x.com/austinvrabel/status/1973084447546208585)  2025-09-30T17:56Z [---] followers, [---] engagements


"$CADL Still 50% of patients elect for radical prostatectomy when faced with Early localized Prostate cancer. I believe the other 50% will elect for a new paradigm in SOC. CAN-2409 + Radiotherapy. Which reduces recurrence by 30-38% On this date in [----] Dr Patrick Walsh performed the first purposeful nerve-sparing radical prostatectomy. Grateful for this and his many other contributions to the world ❤🙏 #AUA24 https://t.co/HHQ4h5motJ On this date in [----] Dr Patrick Walsh performed the first purposeful nerve-sparing radical prostatectomy. Grateful for this and his many other contributions to the"  
[X Link](https://x.com/austinvrabel/status/1973084786286604799)  2025-09-30T17:57Z [---] followers, [---] engagements


"$CADL Really enjoyed hearing Dr. Sylvester speak as a KOL on how CAN-2409 could be a gamer changer Not only to patients but also doctors around the country in Early Localized intermediate/ high risk prostate cancer. Some more great exposure https://grandroundsinurology.com/fdus/ Our prostate cancer data from the phase [--] CAN-2409 trial will be presented in an oral presentation at the Future Directions in Urology Symposium by Dr. John E. Sylvester from Atlantic Urology Clinics. https://t.co/xglePNaEpq #ProstateCancer #Urology $CADL https://t.co/TbqnBTUAdi https://grandroundsinurology.com/fdus/"  
[X Link](https://x.com/austinvrabel/status/1973417979783303602)  2025-10-01T16:01Z [---] followers, [---] engagements


"$CADL Fully convinced CAN-2409 is a blockbuster in Early localized intermediate/ high risk prostate cancer. Question in my mind is how many billions"  
[X Link](https://x.com/austinvrabel/status/1974951680866406578)  2025-10-05T21:35Z [---] followers, [---] engagements


"$CADL Non- dilutive funding & thats what we got PPT kept his word. Would you rather we issue 22M shares to raise 130M Hell no. This is great news Everything comes at a cost its part of doing business. NSCLC today got pushed forward. Phase [--] incoming"  
[X Link](https://x.com/austinvrabel/status/1978259758843900331)  2025-10-15T00:40Z [---] followers, [---] engagements


"$CADL Our fearless leader at the Prostate Cancer Foundation Great work PPT What an amazing road ahead"  
[X Link](https://x.com/austinvrabel/status/1981872390209737159)  2025-10-24T23:56Z [---] followers, [---] engagements


"$CADL really looking forward to this panel discussion on Nov 7th with Candel Therapeutics @bradloncar at SITC [----]. https://www.sitcancer.org/2025/schedule/sitc25-annualmeeting#tab1 https://www.sitcancer.org/2025/schedule/sitc25-annualmeeting#tab1"  
[X Link](https://x.com/austinvrabel/status/1983021283236536445)  2025-10-28T04:01Z [---] followers, [---] engagements


"$CADL Additional coverage today from Stephens @Stephens_Inc with a $15 price target. An idea ready to go Viral. https://www.stephens.com/institutional-equities-and-research/people/sudan-loganathan-phd https://www.stephens.com/institutional-equities-and-research/people/sudan-loganathan-phd"  
[X Link](https://x.com/anyuser/status/1983024224873893978)  2025-10-28T04:13Z [---] followers, [---] engagements


"$CADL next week on Fri Nov 7th our team will be presenting at the SITC [----] Annual Meeting"  
[X Link](https://x.com/austinvrabel/status/1984456733641883984)  2025-11-01T03:05Z [---] followers, [---] engagements


"@paulpetertak @AlienHocke16905 @CandelTx Agree with you PPT. In todays market many visionary CEOs whether its Alex Karp at PLTR Elon Musk at TSLA or Sam Altman at OpenAI are HIGHLY engaged with how their company is valued because it directly affects mission momentum and shareholder confidence"  
[X Link](https://x.com/austinvrabel/status/1986229715120889959)  2025-11-06T00:30Z [---] followers, [---] engagements


"@da_sails @UnoMasReactor This must also be great news for $IMSR . Many of the team members at Oak Ridge are now at terrestrial working on their molten salt reactor"  
[X Link](https://x.com/austinvrabel/status/2008264236888453499)  2026-01-05T19:48Z [---] followers, [---] engagements


"$CADL Q2 2026- We are looking at an additional 15-18 months since Dec [----] Phase [--] readout. The med follow up in the trial was [----] months. Which is meaningful. Still long before OS becomes meaningful but DFS should be very interesting. Further separation"  
[X Link](https://x.com/anyuser/status/2021441909034713236)  2026-02-11T04:31Z [---] followers, [---] engagements


"$CADL Carl June- Tuning into the cell & gene therapy discussions with FDA. Its very enlightening to hear the FDA being so open to hearing from the best in the field. So many changes coming https://www.youtube.com/live/0qDhRtnHXdUsi=Wjnf1ugEA93sg88I https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-partners-university-pennsylvanias-center https://www.youtube.com/live/0qDhRtnHXdUsi=Wjnf1ugEA93sg88I https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-partners-university-pennsylvanias-center"  
[X Link](https://x.com/austinvrabel/status/1931181494900293956)  2025-06-07T02:48Z [---] followers, [---] engagements


"$CADL @Patriots @CoachVrabel50 plz reach out to @paulpetertak on Prostate cancer treatment He may be able to help. He is CEO of company called Candel Therapeutics TOP in class early localized prostate cancer drug coming to market soon. They are located in Needham. Coach Vrabel provides an update on defensive coordinator Terrell Williams. https://t.co/wUksEnTEkL Coach Vrabel provides an update on defensive coordinator Terrell Williams. https://t.co/wUksEnTEkL"  
[X Link](https://x.com/austinvrabel/status/1971701321914060914)  2025-09-26T22:20Z [---] followers, [---] engagements


"$CADL Another great opportunity Looking forward to hearing more about enLIGHTEN. PPT at the panel discussion should be great https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-present-sitc-2025-annual-meeting https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-present-sitc-2025-annual-meeting"  
[X Link](https://x.com/austinvrabel/status/1974113791010091520)  2025-10-03T14:06Z [---] followers, [---] engagements


"$CADL Glad they made this correction due to loyal shareholder complaints. Even still such terrible English and grammar"  
[X Link](https://x.com/austinvrabel/status/1990241445991919654)  2025-11-17T02:11Z [---] followers, [---] engagements


"$CADL WOW what a day coming up STACKED lineup of speakers on Research advisory board and analysts as moderators 1) https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-host-virtual-rd-event-december-5-2025 https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-host-virtual-rd-event-december-5-2025"  
[X Link](https://x.com/anyuser/status/1990590725931872383)  2025-11-18T01:19Z [---] followers, [---] engagements


"$CADL Another de-risking event Great news https://www.statnews.com/2025/12/04/fda-considers-single-clinical-trial-for-new-product-approvals/ https://www.statnews.com/2025/12/04/fda-considers-single-clinical-trial-for-new-product-approvals/"  
[X Link](https://x.com/anyuser/status/1996801216291189081)  2025-12-05T04:38Z [---] followers, [---] engagements


"Q2 2026- We are looking at an additional 15-18 months since Dec [----] Phase [--] readout. The med follow up in the trial was [----] months. Which is meaningful. Still long before OS becomes meaningful but DFS should be very interesting. Further separation"  
[X Link](https://x.com/austinvrabel/status/2021440786538397744)  2026-02-11T04:26Z [---] followers, [--] engagements


"$CADL [--] patients were alive [--] months. 37% of n=41. You have to keep in mind:This is from cohort [--] which was stage [--] cancer patients with progressive disease who had failed ICI and chemoJust look at those staggering survival numbers. SOC mOS is 9.8-11 months"  
[X Link](https://x.com/anyuser/status/2021812967764111869)  2026-02-12T05:05Z [---] followers, [---] engagements


"$CADL [--] patients were alive [--] months. 37% of n=41. You have to keep in mind:This is from cohort [--] which was stage [--] cancer patients with progressive disease who had failed ICI and chemoJust look at those staggering survival numbers. SOC mOS is 9.8-11 months"  
[X Link](https://x.com/anyuser/status/2021812967764111869)  2026-02-12T05:05Z [---] followers, [---] engagements


"several patients WELL well beyond. Look at those bottom numbers in the table"  
[X Link](https://x.com/anyuser/status/2021813097074495588)  2026-02-12T05:06Z [---] followers, [--] engagements


"$CADL Q2 2026- We are looking at an additional 15-18 months since Dec [----] Phase [--] readout. The med follow up in the trial was [----] months. Which is meaningful. Still long before OS becomes meaningful but DFS should be very interesting. Further separation"  
[X Link](https://x.com/anyuser/status/2021441909034713236)  2026-02-11T04:31Z [---] followers, [---] engagements


"We already have a slam dunk but this is potential nail in the coffin. Not to mention mgmt is executing meticulously on CMC front"  
[X Link](https://x.com/anyuser/status/2021441991624806469)  2026-02-11T04:31Z [---] followers, [--] engagements


"Terrestrial Energy executes DOE agreement for Project TETRA under Advanced Reactor Pilot Program. Our pilot IMSR reactor will demonstrate clean firm nuclear energy using readily available SALEU fuel positioning us to move quickly from design to operation under DOE authorization. "This OTA is a partnership with the U.S. Department of Energy to accelerate development licensing and operation of IMSR plants servicing critical energy needs" stated Simon Irish CEO of Terrestrial Energy. "The agreement sits on our development center-path allowing the Company to expedite key elements of its program"  
[X Link](https://x.com/anyuser/status/2008525950045081941)  2026-01-06T13:07Z [----] followers, 18.4K engagements


"Next week our executive team will be in San Francisco for the J.P. Morgan Healthcare Conference. We look forward to connecting with industry leaders and the investor community. Hope to see you there #JPM2026 #Healthcare #Biotech $CADL"  
[X Link](https://x.com/anyuser/status/2008554314508247390)  2026-01-06T15:00Z [---] followers, [----] engagements


"As [----] draws to a close we reflect on what an incredible year it has been. Were grateful for our dedicated team supportive partners and the patients who inspire our mission every day. Wishing everyone peace joy and continued optimism in the fight against cancer"  
[X Link](https://x.com/anyuser/status/2003495594145296737)  2025-12-23T15:59Z [---] followers, [---] engagements


"Were thrilled to announce that Candel has been honored at the Scrip Awards [----] This recognition celebrates our successful phase [--] study of CAN-2409 in localized prostate cancer. Thank you to @Citeline for this honor. https://www.citeline.com/en/awards/scripawards https://www.citeline.com/en/awards/scripawards"  
[X Link](https://x.com/anyuser/status/1999472817062941060)  2025-12-12T13:34Z [---] followers, [----] engagements


"Dr. Glen Gejerman spoke to @UrologyTimes about Candels phase [--] trial results for CAN-249 in localized intermediate- to high-risk prostate cancer presented at ASTRO [----]. Tune into this insightful video to hear more. https://www.urologytimes.com/view/glen-gejerman-md-highlights-phase-3-data-on-can-2409-in-localized-prostate-cancer https://www.urologytimes.com/view/glen-gejerman-md-highlights-phase-3-data-on-can-2409-in-localized-prostate-cancer"  
[X Link](https://x.com/anyuser/status/1998769889046061088)  2025-12-10T15:00Z [---] followers, [----] engagements


"$CADL Another de-risking event Great news https://www.statnews.com/2025/12/04/fda-considers-single-clinical-trial-for-new-product-approvals/ https://www.statnews.com/2025/12/04/fda-considers-single-clinical-trial-for-new-product-approvals/"  
[X Link](https://x.com/anyuser/status/1996801216291189081)  2025-12-05T04:38Z [---] followers, [---] engagements


"$CADL WOW what a day coming up STACKED lineup of speakers on Research advisory board and analysts as moderators 1) https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-host-virtual-rd-event-december-5-2025 https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-host-virtual-rd-event-december-5-2025"  
[X Link](https://x.com/anyuser/status/1990590725931872383)  2025-11-18T01:19Z [---] followers, [---] engagements


"$CADL Glad they made this correction due to loyal shareholder complaints. Even still such terrible English and grammar"  
[X Link](https://x.com/austinvrabel/status/1990241445991919654)  2025-11-17T02:11Z [---] followers, [---] engagements


"$CADL in regards to Mechanistic study of CAN-2409 in localized prostate cancer. This is just lab work deep immunologic Biomarker data FDA wants to support BLA. Data in Q3 2026"  
[X Link](https://x.com/anyuser/status/1989047081970069921)  2025-11-13T19:05Z [---] followers, [----] engagements


"Well be sharing data from our CAN-2409 program in NSCLC & and our enLIGHTEN Discovery Platform. Our CEO @paulpetertak will give a presentation on the phase [--] clinical trial of CAN-2409 in prostate cancer. More details: https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-showcases-immunotherapy-leadership-sitc-2025 https://ir.candeltx.com/news-releases/news-release-details/candel-therapeutics-showcases-immunotherapy-leadership-sitc-2025"  
[X Link](https://x.com/anyuser/status/1985712732239237616)  2025-11-04T14:16Z [---] followers, [----] engagements


"$CADL next week on Fri Nov 7th our team will be presenting at the SITC [----] Annual Meeting"  
[X Link](https://x.com/austinvrabel/status/1984456733641883984)  2025-11-01T03:05Z [---] followers, [---] engagements


"$CADL Additional coverage today from Stephens @Stephens_Inc with a $15 price target. An idea ready to go Viral. https://www.stephens.com/institutional-equities-and-research/people/sudan-loganathan-phd https://www.stephens.com/institutional-equities-and-research/people/sudan-loganathan-phd"  
[X Link](https://x.com/anyuser/status/1983024224873893978)  2025-10-28T04:13Z [---] followers, [---] engagements

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