#  @ZKForTre 🐊ZK For Tre🐊 🐊ZK For Tre🐊 posts on X about in the, health, this is, if you the most. They currently have [-----] followers and [----] posts still getting attention that total [------] engagements in the last [--] hours. ### Engagements: [------] [#](/creator/twitter::236967067/interactions)  - [--] Week [------] +170% - [--] Month [------] +9.80% - [--] Months [-------] +242% - [--] Year [-------] -30% ### Mentions: [--] [#](/creator/twitter::236967067/posts_active)  - [--] Months [---] -23% - [--] Year [---] -48% ### Followers: [-----] [#](/creator/twitter::236967067/followers)  - [--] Week [-----] +0.51% - [--] Month [-----] +0.79% - [--] Months [-----] +7.50% - [--] Year [-----] +15% ### CreatorRank: [-------] [#](/creator/twitter::236967067/influencer_rank)  ### Social Influence **Social category influence** [finance](/list/finance) [technology brands](/list/technology-brands) [countries](/list/countries) [celebrities](/list/celebrities) [stocks](/list/stocks) [us election](/list/us-election) [social networks](/list/social-networks) [cryptocurrencies](/list/cryptocurrencies) [travel destinations](/list/travel-destinations) [automotive brands](/list/automotive-brands) **Social topic influence** [in the](/topic/in-the), [health](/topic/health), [this is](/topic/this-is), [if you](/topic/if-you), [money](/topic/money), [elon musk](/topic/elon-musk), [study](/topic/study), [tre](/topic/tre) #949, [rfk](/topic/rfk), [weight loss](/topic/weight-loss) **Top accounts mentioned or mentioned by** [@sirajahashmi](/creator/undefined) [@ewarren](/creator/undefined) [@gugahimself](/creator/undefined) [@northflsparky](/creator/undefined) [@honestballfan13](/creator/undefined) [@elonmusk](/creator/undefined) [@doctortro](/creator/undefined) [@alexjleaf](/creator/undefined) [@biolayne](/creator/undefined) [@fellowshipnate](/creator/undefined) [@nacholeber](/creator/undefined) [@theproof](/creator/undefined) [@skl2433](/creator/undefined) [@drmuniyappa](/creator/undefined) [@justinredalen](/creator/undefined) [@michaelmindrum](/creator/undefined) [@carnivoreaureli](/creator/undefined) [@emarksalot](/creator/undefined) [@robertkennedyjr](/creator/undefined) [@raphaels7](/creator/undefined) **Top assets mentioned** [GLP1 (GLP1)](/topic/glp1) [Alphabet Inc Class A (GOOGL)](/topic/$googl) [Bitcoin (BTC)](/topic/bitcoin) [Tesla, Inc. (TSLA)](/topic/tesla) ### Top Social Posts Top posts by engagements in the last [--] hours "Fox News voters consistently rank as the least informed and most factually inaccurate voters and individuals among news watchers. Forgive me if I dont care about this stupid attempt to shame CNN. LOL @CNN just interviewed a random person at the Gillum rally who said Obamas presence helped influence her vote and it turned out she was Gillums mom. 😑 LOL @CNN just interviewed a random person at the Gillum rally who said Obamas presence helped influence her vote and it turned out she was Gillums mom. 😑" [X Link](https://x.com/ZKForTre/status/1058940362704777216) 2018-11-04T04:33Z [----] followers, [--] engagements "There is no more paranoid group on the internet (well short of flat earthers) than the LC/Keto/Carnivore evangelists. Id say get to get a hobby to fill the time but internet evangelizing is probably taking up a lot of that time. Heh-heh . looks like "Fat Head" is the next target of @Wikipedia's Soviet-style cleansing of the historical record. (You see comrades we cannot allow the proletariat to be confused by entries about people and films that actually exist but question the party's principles.) Heh-heh . looks like "Fat Head" is the next target of @Wikipedia's Soviet-style cleansing of the" [X Link](https://x.com/ZKForTre/status/1075821923026825216) 2018-12-20T18:35Z [----] followers, [--] engagements "@Kitt_S_N_Koola @The_Nutrivore @snoosphere @DaveKeto @TuckerGoodrich It doesnt get shut down. Statins are competitive inhibitors and dosed to reduce not eliminate. Eliminating would mean death. Cells still get sufficient lipids they just upregulation the amount that come from circulation" [X Link](https://x.com/ZKForTre/status/1207441271758970880) 2019-12-18T23:23Z [----] followers, [--] engagements "For once hoping for sulphoraphane and HSPs if/when i get to it. Please please not Vit D =/= COVID. Please. Some incredibly important information on the podcast today from the great and powerful @foundmyfitness Dr Rhonda Patrick is one of my all time favorite guests and absolutely one of the most brilliant people I know. https://t.co/fy69KiZMIN Some incredibly important information on the podcast today from the great and powerful @foundmyfitness Dr Rhonda Patrick is one of my all time favorite guests and absolutely one of the most brilliant people I know. https://t.co/fy69KiZMIN" [X Link](https://x.com/ZKForTre/status/1261019994885890048) 2020-05-14T19:46Z [----] followers, [--] engagements "@DaveKeto @siobhan_huggins Not to be a wet blanket but b-cell phagocytosis and self antigen presentation represents quite a small subset of b-cell/lympocyte activation. The co-stimulatory signals provided by APCs massively increase proliferation and response as well. Absolutely a cool mechanism though" [X Link](https://x.com/ZKForTre/status/1262530919782645762) 2020-05-18T23:50Z [----] followers, [--] engagements "@DaveKeto @siobhan_huggins driven expansion too. Again just hard to take the methods used in the paper and call it representative. In clonal expansions of B-cells (like a culture) (as in germinal centers) co-stimulation by t-cells APCs and cytokines has occurred. If working as APC less so" [X Link](https://x.com/ZKForTre/status/1262557521048268801) 2020-05-19T01:35Z [----] followers, [--] engagements "The United States in [----] described in one tweet. Americans have been consistently very wrong. https://t.co/7bcCtwcYJz https://t.co/v5GjSWHfe7 Americans have been consistently very wrong. https://t.co/7bcCtwcYJz https://t.co/v5GjSWHfe7" [X Link](https://x.com/ZKForTre/status/1292153639457497088) 2020-08-08T17:40Z [----] followers, [--] engagements "Having GameStop the first week in august is now worth more than having Bitcoin at $1000" [X Link](https://x.com/ZKForTre/status/1354137568393224193) 2021-01-26T18:42Z [----] followers, [--] engagements "@Chrest_brett Combining genetics and metabolic targets for individual tumors holds the key if I were to guess. Not for initial treatment but for recurrence or eliminating cancer stem cells" [X Link](https://x.com/ZKForTre/status/1521003126362357761) 2022-05-02T05:46Z [----] followers, [--] engagements "Using the structure of this graphic a bowl of cheerios a protein shake and a fish oil is just about the healthiest thing one can consume. Stupid games stupid prizes. Imagine thinking that Red Meat is bad for you. https://t.co/2UZEAjIYti Imagine thinking that Red Meat is bad for you. https://t.co/2UZEAjIYti" [X Link](https://x.com/ZKForTre/status/1577185982385823744) 2022-10-04T06:36Z [----] followers, [--] engagements "Free speech absolutist until it negatively impacts me. Any account doxxing real-time location info of anyone will be suspended as it is a physical safety violation. This includes posting links to sites with real-time location info. Posting locations someone traveled to on a slightly delayed basis isnt a safety problem so is ok. Any account doxxing real-time location info of anyone will be suspended as it is a physical safety violation. This includes posting links to sites with real-time location info. Posting locations someone traveled to on a slightly delayed basis isnt a safety problem so" [X Link](https://x.com/ZKForTre/status/1603186911228887041) 2022-12-15T00:35Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 Had your argument been absolutely hardline including a rejection of legacy admissions I could have at least acknowledged the case but now were are kind of just pulling from all sides haha" [X Link](https://x.com/ZKForTre/status/1674601863159717890) 2023-06-30T02:12Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 I think I can illustrate the point in [--] simple questions. [--]. For the majority of the lifespan on affirmative action laws (we can talk about recent caveats at the end of you want) do you believe/agree that a college degree was a strong stool of upward mobility in this country" [X Link](https://x.com/ZKForTre/status/1674602265322061824) 2023-06-30T02:14Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 If you mean in the last 10-20 years then fine. These were the caveats I was talking about driven mostly by rapid price escalation. Before that (and to a less extent now) we can agree that data fairly convincingly shows upward mobility for college graduates" [X Link](https://x.com/ZKForTre/status/1674604874523090948) 2023-06-30T02:24Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 I mean there is strong evidence that just isnt true at least at Harvard" [X Link](https://x.com/anyuser/status/1674606014476288002) 2023-06-30T02:29Z [--] followers, [--] engagements "@AlexJLeaf @SKl2433 I am of the opinion that the majority of people in this country arent that different in terms of raw horsepower. So then the mostly reasonable interpretation here is that some kids were born into harder circumstances and did the same the kids that were born into" [X Link](https://x.com/ZKForTre/status/1674611066855211008) 2023-06-30T02:53Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 Better circumstances would have done in the same spot. Then we propagated that difference via social and even legislative forces for decades such that the gap in circumstances became quite significant at the population level" [X Link](https://x.com/ZKForTre/status/1674611460532518912) 2023-06-30T02:50Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 What affirmative action policies did then is took some of the kids that performed the same as the kids in the good circumstance if you adjust for circumstances. Its not razor-precise but it does increase the opportunity for mobility of people who were" [X Link](https://x.com/ZKForTre/status/1674611832688984065) 2023-06-30T02:52Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 But it remains an instrument to take a certain percentage of members of marginalized communities and enable them to have the same upward mobility tool. They are also more likely to reinvest that capital in their communities that an alternative candidate would be" [X Link](https://x.com/ZKForTre/status/1674613231136956417) 2023-06-30T02:58Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 From a summative article: The study published earlier this month in the National Bureau of Economic Research found that [--] percent of white students admitted to Harvard University were recruited athletes legacy students children of faculty and staff" [X Link](https://x.com/ZKForTre/status/1674613872299319296) 2023-06-30T03:00Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 Im struggling to appreciate any interpretation in which these arent in all but letter of the law exactly the same thing" [X Link](https://x.com/ZKForTre/status/1674616333768482817) 2023-06-30T03:12Z [----] followers, [--] engagements "@AlexJLeaf @SKl2433 Like at best this is being okay with a passive version of the activity but being against an active one that was initially implemented to combat the passive version" [X Link](https://x.com/anyuser/status/1674616500043358209) 2023-06-30T03:12Z [--] followers, [--] engagements "@DudzLightLime @dr_muniyappa @Drlipid @MattBMartin The former is my understanding for sure. I think Shulman among others has put a nice bow on that story But if thats the case how is a relatively stable hypoglycemia achieved in genetic conditions The normal arrows that drive glucose control get mixed at least a bit right" [X Link](https://x.com/ZKForTre/status/1674617338778341377) 2023-06-30T03:16Z [----] followers, [--] engagements "@DudzLightLime @dr_muniyappa @Drlipid @MattBMartin No no I hope I dont start asking question that sense haha. I meant more than in the context that primary hyperinsulinemia drives some degree of IR (as some believe is relevant even in T2DM pathogenesis) how does this integrate into initial glycemia regulations" [X Link](https://x.com/ZKForTre/status/1674619640008306690) 2023-06-30T03:23Z [----] followers, [--] engagements "This individual is approaching half a million followers in case you were wondering where the quality of discourse is at" [X Link](https://x.com/ZKForTre/status/1677864892466974721) 2023-07-09T02:20Z [----] followers, [----] engagements "@Chrest_brett Cancer mitochondria probably not as dysfunctional as once presumed" [X Link](https://x.com/ZKForTre/status/1678562818499526657) 2023-07-11T00:32Z [----] followers, [---] engagements "I do think the rebuttal questions do have to be more inciting in cases like this but I also dont know the challenges of quarterbacking such a show" [X Link](https://x.com/ZKForTre/status/1678591962327154688) 2023-07-11T02:28Z [----] followers, [---] engagements "Now do glucose. Cholesterol is essential https://t.co/8Lb1yh2IMQ Cholesterol is essential https://t.co/8Lb1yh2IMQ" [X Link](https://x.com/ZKForTre/status/1691878729545294125) 2023-08-16T18:24Z [----] followers, [----] engagements "@TheNutrivore I get a kick out people who claim to have optimal metabolic health being entirely destroyed by a couple of grams of added PUFA" [X Link](https://x.com/ZKForTre/status/1693381061403611618) 2023-08-20T21:54Z [----] followers, [----] engagements "I posted my lowest lifetime A1c (4.8) despite having more carbs and a lower diet qualify overall (still good but more garbage in total) in recent months. Go figure" [X Link](https://x.com/ZKForTre/status/1694045343158038538) 2023-08-22T17:54Z [----] followers, [----] engagements "@gerdosi @MJ18912000 Its pretty conclusive though. Maybe there will be a strong signal in the future (though the plausibility of that kind of lag time is highly questionable) but it hasnt materialized. Obviously if it does that is need-to-know information" [X Link](https://x.com/ZKForTre/status/1694370509805310318) 2023-08-23T15:26Z [----] followers, [--] engagements "No one argues that obesity is as simple as counting calories these days. This is a straw man. What the argument actually is is that caloric balance is the inescapable underwriting principle that determines weight balance. Many strategies are in service of that target" [X Link](https://x.com/ZKForTre/status/1694734152262729922) 2023-08-24T15:31Z [----] followers, [----] engagements "Very little evidence that glyphosate at human exposure levels does much of anything. Glyphosate is so harmful for humans. And its sprayed all over your oatmeal Organic oats arent that much better see the threads https://t.co/iXBfnTbVwW Glyphosate is so harmful for humans. And its sprayed all over your oatmeal Organic oats arent that much better see the threads https://t.co/iXBfnTbVwW" [X Link](https://x.com/ZKForTre/status/1694833821135274213) 2023-08-24T22:07Z [----] followers, [----] engagements "@ketogrillbakery @nicknorwitz @davidludwigmd @AdrianSotoMota @DoctorTro I cannot emphasize beyond this last time that this is addressed in the article. Very early in it in fact. This constant rewinding is becoming frivolous" [X Link](https://x.com/ZKForTre/status/1695143072428904534) 2023-08-25T18:36Z [----] followers, [--] engagements "@ketogrillbakery @ESpacetime @DoctorTro So let me drill down to brass tax here. You are parroting Nick who is partying Adrian. About right" [X Link](https://x.com/ZKForTre/status/1695147101838069976) 2023-08-25T18:52Z [----] followers, [--] engagements "@TheNutrivore He is a serial reflexive blocker. The irony here is palpable" [X Link](https://x.com/ZKForTre/status/1695839902997393459) 2023-08-27T16:45Z [----] followers, [---] engagements "@VigilantFox @joerogan He left because of taxes. It was taxes. My goodness" [X Link](https://x.com/ZKForTre/status/1698143569029054534) 2023-09-03T01:19Z [----] followers, [----] engagements "@Rickyg668620362 @VigilantFox @joerogan It literally would be the 5th or 6th largest economy in the world if it were its own country. But sure economically and financially unsustainable" [X Link](https://x.com/ZKForTre/status/1698180482377060748) 2023-09-03T03:45Z [----] followers, [--] engagements "@Rickyg668620362 @VigilantFox @joerogan The business of homelessness. Ive rarely heard such an esoteric suggestion of net profitability. You havent even touched on a top [--] industry in California. Ill let you try again if you want" [X Link](https://x.com/ZKForTre/status/1698186972915810454) 2023-09-03T04:11Z [----] followers, [--] engagements "@Rickyg668620362 @VigilantFox @joerogan There are literally economic statistics that are easily google-able. California is a net contributor. Im going to need you to try to reference some actual datasets and not whatever hyper-politicized fever dreams youve been listening to" [X Link](https://x.com/ZKForTre/status/1698188031507787829) 2023-09-03T04:15Z [----] followers, [--] engagements "@dbechek1 @GeoffreyStreve1 @EricRWeinstein You do realize though that it is what established prices during a period or record inflation right Those prices dont now go down. Nor are those profits solely from retailers. Consumption has continued to rise even in spite of inflated prices" [X Link](https://x.com/ZKForTre/status/1698336936245555441) 2023-09-03T14:07Z [----] followers, [--] engagements "@dbechek1 @GeoffreyStreve1 @EricRWeinstein Moreover estimate levels of inflation that were contributed by corporate price hikes was between [--] and 60% higher by any metric that fiscal stimulus or even supply chain breakdowns in isolation. Record quarterly profits were being realized in the Same inflationary environment" [X Link](https://x.com/ZKForTre/status/1698339923638526079) 2023-09-03T14:19Z [----] followers, [--] engagements "@dbechek1 @GeoffreyStreve1 @EricRWeinstein It is so funny to hear you claim a high ground now [--]. I am literally just echoing the conclusions of multiple economists [--]. You were the one who went on and on and on about fiscal stimulus being the cause of inflation (I can pull up there tweets) and that the USs stimulus" [X Link](https://x.com/ZKForTre/status/1698384377225359682) 2023-09-03T17:16Z [----] followers, [--] engagements "@Justinredalen There is literally more evidence they work in an individual basis than a population basis. See above. Also they cannot work on a population basis if they do not work in an individual basis. Whatever" [X Link](https://x.com/ZKForTre/status/1698721538176958761) 2023-09-04T15:35Z [----] followers, [--] engagements "@Jodie_Boisvert It will come back in time. Not for the material you read regularly but for other topics. If you want a bridge audiobooks can kind of ease you back into reading without actually having to look at more text" [X Link](https://x.com/ZKForTre/status/1698760602502488122) 2023-09-04T18:11Z [----] followers, [--] engagements "@ScepticalDoctor @DudzLightLime @PlantChompers Also saying ldl/ApoB rises because of fat adaptation is a physiological tautology and is a good example of the imprecise language being derided the tweet prior" [X Link](https://x.com/ZKForTre/status/1698767683188044151) 2023-09-04T18:39Z [----] followers, [---] engagements "@ScepticalDoctor @DudzLightLime @PlantChompers Bottom line people with low levels of insulin resistance are going to be at less risk of ascvd endpoints because IR is either a causal risk factor and/or an iterative variable on ApoB. Individuals with low ApoC3 (usually invoked as a proxy of low trigs and remnants by the low" [X Link](https://x.com/ZKForTre/status/1698768441291747814) 2023-09-04T18:42Z [----] followers, [--] engagements "@ScepticalDoctor @DudzLightLime @PlantChompers If their LDL is [---] and they have good glycemic control and low insulin their whole (adult) life would their increased risk be especially high Idk for sure maybe not. Would it be higher than if there ldl was [--] Almost all evidence says yes" [X Link](https://x.com/ZKForTre/status/1698778927873872146) 2023-09-04T19:23Z [----] followers, [--] engagements "@ScepticalDoctor @DudzLightLime @PlantChompers People are free to make their conclusions from there. Even if they didnt want to take a statin just taking Zetia would be a decent buffer for people going down this road. [--] of rosuvastatin and low dose zetia would give them the best of both 🤷♂" [X Link](https://x.com/ZKForTre/status/1698779339758723400) 2023-09-04T19:25Z [----] followers, [--] engagements "@MakaiOokami @DoctorTro [--]. Non-sequitur [--]. The evidence that reductions in sugar intakes meaningfully improves AD(H)D is shockingly poor" [X Link](https://x.com/ZKForTre/status/1698884445606949266) 2023-09-05T02:23Z [----] followers, [--] engagements "I re-amazed almost every week by how so many on this app specifically have been able to monetize or derive social capital from claiming completely invented persecution. Its always from those who claim to be rebellious free thinkers which these days might not mean much" [X Link](https://x.com/ZKForTre/status/1700627023809384647) 2023-09-09T21:47Z [----] followers, [----] engagements "Or you know just prefers something different than you. Everyone who says strip has been brainwashed and/or bullied by their cardiologist into fearing fat and cholesterol. Everyone who says strip has been brainwashed and/or bullied by their cardiologist into fearing fat and cholesterol" [X Link](https://x.com/ZKForTre/status/1700699964782092497) 2023-09-10T02:37Z [----] followers, [---] engagements "@CaloriesProper Doesnt his wife also sell keto baking mixes or something" [X Link](https://x.com/ZKForTre/status/1700727340320292935) 2023-09-10T04:26Z [----] followers, [--] engagements "@Timcast Imagine in the morass of what you regularly defend or explain away identifying this endeavor as evil" [X Link](https://x.com/ZKForTre/status/1702800207203737918) 2023-09-15T21:43Z [----] followers, [--] engagements "Nope. Still a calorie problem. Thanks for the thought though" [X Link](https://x.com/ZKForTre/status/1703454082168455397) 2023-09-17T17:01Z [----] followers, [----] engagements "I can imagine few things Im less interested in than Hubermans take on seed oils/PUFAs" [X Link](https://x.com/ZKForTre/status/1704237387436495266) 2023-09-19T20:53Z [----] followers, [----] engagements "@fire_bottle RCTs with hard outcomes on a nutrient is virtually impossible to conduct or fund in the modern day. The old ones that tried almost universally had brutal flaws. You are left to conduct shorter studies and then extrapolate which people are terrible at" [X Link](https://x.com/ZKForTre/status/1705114119265796254) 2023-09-22T06:57Z [----] followers, [--] engagements "We live in the dumbest timeline" [X Link](https://x.com/ZKForTre/status/1705141298921894196) 2023-09-22T08:45Z [----] followers, [---] engagements "To the whole keto/carnivore crowd you are very very fond of claiming your voice is suppressed at various levels. Youll have to explain the following to me then: Dave Feldman: blocked me have repeated offered to discuss/debate all rejected aside from offering to have a beer" [X Link](https://x.com/ZKForTre/status/1706055920113914107) 2023-09-24T21:20Z [----] followers, [----] engagements "Ivor Cummins: blocked after constant attempts to get him to answer basic methodological questions (I realize hes now moved on to COVID grifts and such now) Ketocarnivore gal: pushed back on her various extrapolations especially regarding mental health instant block" [X Link](https://x.com/ZKForTre/status/1706055925344125434) 2023-09-24T21:20Z [----] followers, [---] engagements "Your gut health will be much better supported by a generally healthy dietary pattern than from consuming lactations as an adult that are meant to bridge an infant mammal during the earliest stages of post-natal development" [X Link](https://x.com/ZKForTre/status/1706792197981348295) 2023-09-26T22:05Z [----] followers, [----] engagements "Worlds richest man and purported super genius unwilling or unable to google vaccine efficacy calculation" [X Link](https://x.com/ZKForTre/status/1706824189762568630) 2023-09-27T00:12Z [----] followers, [---] engagements "@JimJohnsonSci @mario_kratz Im going to hold off on wasting your time asking about the details until Ive had time to dive more into this literature" [X Link](https://x.com/ZKForTre/status/1707148180293374385) 2023-09-27T21:40Z [----] followers, [--] engagements "This is the football contract equivalent of offering an RB2 and a WR2 for a blue chip player. His open market value is like 50% higher than this minimum. This offer is insulting (and Im lukewarm on Kirk at best)" [X Link](https://x.com/ZKForTre/status/1708225711788499302) 2023-09-30T21:02Z [----] followers, [---] engagements "Not trying to rip the explanation given as to the sales pitch its actually pretty transparent. I just cant even imagine his agent running it by him given that number. Id try 3/$80 and expect a sizable counter" [X Link](https://x.com/ZKForTre/status/1708226128983269655) 2023-09-30T21:03Z [----] followers, [--] engagements "@KevinH_PhD Sorry probably shouldnt have tagged you. Its not apples-to-apples but Im referring to this. The paradigms are definitely not the same should have been more careful With the characterization" [X Link](https://x.com/ZKForTre/status/1714333917891666355) 2023-10-17T17:33Z [----] followers, [---] engagements "@AlexMicheletti Im starting to worry about him (or maybe his dad). Now hes saying he wants an ownership stake in whatever teams drafts him (if I read correctly)" [X Link](https://x.com/ZKForTre/status/1715952557799911711) 2023-10-22T04:45Z [----] followers, [---] engagements "@anymanfitness But the job/employment environment does contribute to that. With relative wage deflation at its current level the ability to live within that kind of radius for employment is a lot lower especially in bigger cities" [X Link](https://x.com/ZKForTre/status/1717320960494178550) 2023-10-25T23:23Z [----] followers, [---] engagements "@fellowshipnate @CarnivoreAureli @BioLayne @EMarksalot 31**. Sorry for the typographical error" [X Link](https://x.com/ZKForTre/status/1717742551321485636) 2023-10-27T03:18Z [----] followers, [---] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot Suggesting that within-individual changes with a co-occurring psych intervention is a placebo is patently false btw" [X Link](https://x.com/ZKForTre/status/1717746816198775211) 2023-10-27T03:35Z [----] followers, [---] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot Therapeutic value in epilepsy is seen for a subset of seizure disorders. Im not arguing thats not the case. But its universality for seizure is a matter of serious debate and the extrapolability to non-seizure disorders is essentially null" [X Link](https://x.com/ZKForTre/status/1717749584229790006) 2023-10-27T03:46Z [----] followers, [--] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot The latter comments are of course frankly nonsense" [X Link](https://x.com/anyuser/status/1717749669961347429) 2023-10-27T03:46Z [--] followers, [--] engagements "@fellowshipnate @CarnivoreAureli @BioLayne @EMarksalot Idk if you guys know this but schizophrenia (what was initially invoked) is not a seizure disorder" [X Link](https://x.com/ZKForTre/status/1717750110950469706) 2023-10-27T03:48Z [----] followers, [--] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot You realize this objection means nothing right" [X Link](https://x.com/ZKForTre/status/1717750245960921149) 2023-10-27T03:49Z [----] followers, [--] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot So let me square this you pivot from schizophrenia to epilepsy at a whim then get worked up when I note that the therapeutic value of ketones (BHB) in seizure disorders may not be universal Neat. Neat" [X Link](https://x.com/ZKForTre/status/1717750664405688583) 2023-10-27T03:50Z [----] followers, [--] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot That fine just so long as you acknowledge that a baseless comment of as much is entirely meaningless" [X Link](https://x.com/ZKForTre/status/1717751194871828841) 2023-10-27T03:52Z [----] followers, [--] engagements "@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot A nebulous term for someone arguing for nebulous endpoints. But sure" [X Link](https://x.com/ZKForTre/status/1717751306687783088) 2023-10-27T03:53Z [----] followers, [--] engagements "@LochNessDragon @CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot Wrong carnivore Aurelius my man. This one has like [--] followers. I got duped too" [X Link](https://x.com/ZKForTre/status/1718447119525355848) 2023-10-29T01:58Z [----] followers, [--] engagements "I dont know that Ive ever understood a move less than this one" [X Link](https://x.com/ZKForTre/status/1719416591148822902) 2023-10-31T18:10Z [----] followers, [---] engagements "@AlexMicheletti Im convinced there is a cultural movement in Brazil that just involves getting AI to do crazy but themed stuff" [X Link](https://x.com/ZKForTre/status/1719947140498145315) 2023-11-02T05:18Z [----] followers, [---] engagements "@galaxysplain This conversation has become such an abstraction that Im not even sure what is being discussed anymore. Should I mute the exchange or can we land on a common point of discussion" [X Link](https://x.com/ZKForTre/status/1721353268805210554) 2023-11-06T02:26Z [----] followers, [--] engagements "@jpegan10 @TheSens1990 @DoctorTro I havent had it measured in years. My last A1c was [---]. Likely given my genetically low LDL my fasting insulin would run slightly higher. But it was [---] last it was measured if I remember correctly. Happy to track it as well if I do this project" [X Link](https://x.com/ZKForTre/status/1721989616524210565) 2023-11-07T20:34Z [----] followers, [--] engagements "@ZsoltNagy7 @DoctorTro You are now hard pivoting from predictions that would be directly made from the conservation of mass principles. I suspected you didnt actually believe it and now weve illustrated you dont. Thanks for playing" [X Link](https://x.com/ZKForTre/status/1723108335459688553) 2023-11-10T22:40Z [----] followers, [--] engagements "@ZsoltNagy7 @DoctorTro In an isocaloric setting when consuming relatively more carbs. Net fat mass comes down to you guessed it overall energy balance. Weve come full circle Im so glad you lead us right to the biochemical principle underwriting adipose flux" [X Link](https://x.com/ZKForTre/status/1723108956782891023) 2023-11-10T22:42Z [----] followers, [--] engagements "@ZsoltNagy7 @DoctorTro Also this paper is about dichotomous energy system switching during exercise used to float an unnecessarily dichotomous view of how energy systems function during exercise" [X Link](https://x.com/ZKForTre/status/1723120244548325448) 2023-11-10T23:27Z [----] followers, [--] engagements "This is such a willfully poor attempt at critiquing SELECT that is makes me wonder if he A) has shorted Novos stock at some point B) just doesnt especially appreciate trial design C) does appreciate the totality of evidence or the ability to correct for a variable (weight)" [X Link](https://x.com/ZKForTre/status/1726260365162680379) 2023-11-19T15:25Z [----] followers, 16.2K engagements "He (and a co-author) essentially spend most of an article setting up an argument thats says yeah this is huge effect size but they didnt have a weight-loss matched control. First of all who cares They had a placebo group to compare event rates to and thats the" [X Link](https://x.com/ZKForTre/status/1726260368643899782) 2023-11-19T15:25Z [----] followers, [---] engagements "Important takeaway. Secondary analysis and partner studies can answer to what extent its weight loss dependent or independent. I tend to like Attia for the most part but the spot in the hill hes carved out for GLP1 drug continues to be just odd" [X Link](https://x.com/ZKForTre/status/1726260371537965452) 2023-11-19T15:25Z [----] followers, [---] engagements "Did you buy a [--] pound bird" [X Link](https://x.com/ZKForTre/status/1727144181993549957) 2023-11-22T01:57Z [----] followers, [----] engagements "Every voter sentiment survey I see heaps criticism on the Biden admin for economic conditions but frankly it should be praise. [--]. S&P up 14% in the last year [--]. Gas down almost [--] cents in recent months [--]. Inflation approaching 3% (borderline miracle [--]. Inflation peak" [X Link](https://x.com/ZKForTre/status/1727405072123089382) 2023-11-22T19:13Z [----] followers, [---] engagements "@AntiheroMD Oh I do love when people bury themselves. If we can agree that retention time in the intimal space correlates with oxidation level we can move on here. Tell me what biomarker is strongly correlated with ApoB particle flux into the vessel wall" [X Link](https://x.com/ZKForTre/status/1727883395567362250) 2023-11-24T02:54Z [----] followers, [--] engagements "@AntiheroMD Trust me I know more about lipidology than you do and Ive spent more time around the nutrition/cardio social media circles than you. Ill be fine. Weve already established LDL oxidation is not necessary for intimal invasion (it literally was in the first set of responses)" [X Link](https://x.com/ZKForTre/status/1727885223692570786) 2023-11-24T03:01Z [----] followers, [--] engagements "@AntiheroMD Oxidation of LDL contents in the intimal space is a core mechanism by which atheroma maturity takes places. Whether recirculated oxidized lipid or lipoprotein contents are a major nidus of atheroma formation is somewhat debatable but they appear to play a small role in a" [X Link](https://x.com/ZKForTre/status/1727885657949745267) 2023-11-24T03:03Z [----] followers, [--] engagements "@AntiheroMD Concentration basis. Now lets get back to business. What serum lipid value correlates with ApoB/LDL particle flux into the intimal space" [X Link](https://x.com/ZKForTre/status/1727885851584078233) 2023-11-24T03:04Z [----] followers, [--] engagements "@AntiheroMD Species on (proportionally very small) peripheral levels the correlations between atheroma burden and plasma levels and what tracing studies exist and you have a nice solid evidence base" [X Link](https://x.com/ZKForTre/status/1727898763073646962) 2023-11-24T03:55Z [----] followers, [--] engagements "@AntiheroMD Tack on the immunohistological differences in vascular lesions relative to serum concentrations total proportion of circulating LDL that is oxidized in any given case and the increased proportion that occurs in individuals specifically following an MI & you have quite the case" [X Link](https://x.com/ZKForTre/status/1727906196919636423) 2023-11-24T04:25Z [----] followers, [--] engagements "@AaronLepeska @AntiheroMD @dylanarmbruste3 I spent half of last night walking him back from retention to SFA increasing ApoB serum levels. He either will have to reject the relationship of ApoB out of whole clothe or is just unaware of the lipid content data regarding impact on ApoB levels. Neither is good" [X Link](https://x.com/ZKForTre/status/1728209954040053844) 2023-11-25T00:32Z [----] followers, [--] engagements "The evidence that heat stress positively influences accumulation or preservation of skeletal muscle is about the same as the evidence that Im a good NBA prospect. The most important players for muscle mass: 1) Protein intake (at least 1.6g/kg body weight) 2) Resistance training 3) Omega-3s (2-4g/day triglyceride form) 4) Heat stress (from a sauna or hot tub) https://t.co/M1oOYx0rV6 The most important players for muscle mass: 1) Protein intake (at least 1.6g/kg body weight) 2) Resistance training 3) Omega-3s (2-4g/day triglyceride form) 4) Heat stress (from a sauna or hot tub)" [X Link](https://x.com/anyuser/status/1728276613178302835) 2023-11-25T04:57Z [----] followers, 26.9K engagements "@DolfDoofinsky Im no apologist for carnivore but thats clearly nonsense" [X Link](https://x.com/ZKForTre/status/1728444789626949790) 2023-11-25T16:05Z [----] followers, [---] engagements "Look for little slices of datasets and case reports that can be used for what technically counts as a publication Or would it be much much better if the same student contributed to just one or two rigorous studies that asked and evaluated important research questions" [X Link](https://x.com/ZKForTre/status/1728562877337145841) 2023-11-25T23:54Z [----] followers, [---] engagements "That a particular field needs answered (but which take a year or more to assess) I know what my answer is. Make the tradeoff in increased workload is just too high idk. We have these brilliant med students going into fantastically competitive specialties that clearly" [X Link](https://x.com/ZKForTre/status/1728562879073542557) 2023-11-25T23:54Z [----] followers, [---] engagements "@MedDevTX @B_Holmer Some people think Bosa is racist is an interesting way to frame the individual saying/endorsing some racist things. This is before getting into some of the other colorful parts of his personality" [X Link](https://x.com/ZKForTre/status/1728598243104416254) 2023-11-26T02:15Z [----] followers, [---] engagements "@JTMarlin77 @MedDevTX @B_Holmer Scouting for an example of an athlete who eschews carbs and landing on that personality because you are just in search of validating a worldview doesnt strike you as at all poetic" [X Link](https://x.com/ZKForTre/status/1728603381969653935) 2023-11-26T02:35Z [----] followers, [--] engagements "@bakrantz So you simply just dont grasp it. You are basically saying (with a dataset that is biased towards underrating the effect size) that one of the biggest demonstrated mortality benefits in medicine (1000 patient-years/95k/4.25 years) even assuming that doesnt compound and" [X Link](https://x.com/ZKForTre/status/1728929527374733725) 2023-11-27T00:11Z [----] followers, [--] engagements "@TPenic @TalkinBaseball_ This is one of the worst copes Ive seen in a long time and I spend a non-trivial amount of time on this app which is the zenith of coping" [X Link](https://x.com/ZKForTre/status/1729225225592537417) 2023-11-27T19:46Z [----] followers, [--] engagements "@TPenic @TalkinBaseball_ It really is only on this site that someone could so definitively argue against their own position and then try to claim some kind of intellectual victory. The unearned intellectual arrogance truly knows no bounds" [X Link](https://x.com/ZKForTre/status/1729237087977943089) 2023-11-27T20:33Z [----] followers, [--] engagements "@TPenic @TalkinBaseball_ You literally just posted the baseball reference page confirming what i said. Im assuming this is trolling because if its not this has entered the realm of being sad" [X Link](https://x.com/ZKForTre/status/1729242520360771891) 2023-11-27T20:55Z [----] followers, [--] engagements "College football has become such a strange game" [X Link](https://x.com/ZKForTre/status/1729564714047267176) 2023-11-28T18:15Z [----] followers, [---] engagements "@TheBhupiThakur @paulsaladinomd @TheNutrivore @drmatthewnagra I am shocked shocked I tell you At the trials hes deemed to be the best of the bunch" [X Link](https://x.com/ZKForTre/status/1729619356261199876) 2023-11-28T21:52Z [----] followers, [---] engagements "@JTMarlin77 You can put me in the camp that at least half of the seed oil trials have such massive flaws that its hard to interpret the aggregated data" [X Link](https://x.com/ZKForTre/status/1729661450665201952) 2023-11-29T00:40Z [----] followers, [--] engagements "@CaloriesProper @hubermanlab Can start with the fact that they are intertwined" [X Link](https://x.com/ZKForTre/status/1730092605797449926) 2023-11-30T05:13Z [----] followers, [--] engagements "@drscottyk I think thats a reasonable take but how would that be actionable independent of what would be done anyway" [X Link](https://x.com/ZKForTre/status/1730660882944786875) 2023-12-01T18:51Z [----] followers, [---] engagements "Ive heard Dean Phillips talk in an extended capacity a half dozen times now. I find him eminently reasonable. Much More than most politicians Ive heard in my lifetime" [X Link](https://x.com/ZKForTre/status/1730675354581258580) 2023-12-01T19:48Z [----] followers, [---] engagements "Changes in glucose metabolism preceding clinical symptoms has been demonstrated in various capacities for at least [--] years. Virtually anyone who was well-versed in the literature has been aware of this relationship and were able to hold neuropathology and cerebrometabolism" [X Link](https://x.com/ZKForTre/status/1730693069899497541) 2023-12-01T20:59Z [----] followers, [----] engagements "In their head at the same time. The grant and clinical space has been dominated by the neuropathology side but its disingenuous to continue to try to bifurcate the interrelationship of the two sides or to suggest metabolism wasnt appreciated" [X Link](https://x.com/ZKForTre/status/1730693072286036006) 2023-12-01T20:59Z [----] followers, [---] engagements "@SweetCainMusic Idk. Its a long conversation that may not be a Friday night topic" [X Link](https://x.com/ZKForTre/status/1730761935279337554) 2023-12-02T01:32Z [----] followers, [--] engagements "Georgia and Bama both roll FSU even with Jordan Travis but you have to put FSU in otherwise why even bother with the regular season" [X Link](https://x.com/ZKForTre/status/1731201630534578397) 2023-12-03T06:40Z [----] followers, [---] engagements "@cohensa I dont think its that cut and dry. Should it be at the discretion of the committee to discount the undefeated ACC champ with a win over LSU because their QB got hurt Thats at best a philosophical discussion where honest brokers might disagree" [X Link](https://x.com/ZKForTre/status/1731210599088959670) 2023-12-03T07:15Z [----] followers, [--] engagements "For instance this paper does the thing that so many do they reference an athlete (LeBron in this case) as a cudgel against BMI. This is so lazy that you lose me instantly. First it is almost never reasonable to use an extreme outlier to categorize a metric broadly. Second" [X Link](https://x.com/ZKForTre/status/1731364513864138841) 2023-12-03T17:27Z [----] followers, [---] engagements "There exists virtually no doctors or prescribers (Im sure you can find a couple of isolated nutcases) that would look at lebron and his profile and say that his BMI is concerning for adiposity. The additional case here is that AO medication cutoffs are BMI dependent" [X Link](https://x.com/ZKForTre/status/1731365750160408845) 2023-12-03T17:32Z [----] followers, [---] engagements "@nacholeber They were doomed either way. Alabama is clearly the superior team as it stands. FSU has the resume. Their mandate is technically to choose the best teams its written into their criteria. I dont love that they can wipe away the regular season based on injury but they can" [X Link](https://x.com/ZKForTre/status/1731371795700236735) 2023-12-03T17:56Z [----] followers, [----] engagements "@AKoutnik I think its reactionary to not having Jordan Travis and having a fairly soft schedule outside of LSU more than it is to one week of games. The argument for reacting to this week is to drop Georgia if anything" [X Link](https://x.com/ZKForTre/status/1731376594281812095) 2023-12-03T18:15Z [----] followers, [--] engagements "If one is drinking to the point they need to be administered NAC and glutathione we need a serious caveat on the amount of alcohol or existing liver disease going on here. Also vitamin C Please 🤦♂" [X Link](https://x.com/ZKForTre/status/1731782976432746925) 2023-12-04T21:10Z [----] followers, [----] engagements "If you conflate lean mass loss with skeletal muscle loss youre going to have a bad time" [X Link](https://x.com/ZKForTre/status/1732979501703872624) 2023-12-08T04:24Z [----] followers, [----] engagements "Its really difficult to combat misinformation in a world where this is viewed as a strong argument. And I say this as someone who is probably more tolerant of neutral sat fat arguments than most. I want to respond to the commenter (to my dec [--] post) who posted a graph showing that cardiovascular deaths have declined since [----] in men and women. This correlation might make one think that the American Heart Association's campaign to lower cholesterol is the driving factor. https://t.co/qdQE2XL0gF I want to respond to the commenter (to my dec [--] post) who posted a graph showing that" [X Link](https://x.com/ZKForTre/status/1733914510451159399) 2023-12-10T18:20Z [----] followers, [----] engagements "That might have been good from 70" [X Link](https://x.com/ZKForTre/status/1734029848413078011) 2023-12-11T01:58Z [----] followers, [---] engagements "Epidemiology is trash science Look at this graph of butter consumption versus obesity rates Yall are going to have to pick one. Butter consumption has dropped 62.5% over the last [---] years while obesity and vegetable oils have soared. Must be the butter. https://t.co/3om0hfVK4i Butter consumption has dropped 62.5% over the last [---] years while obesity and vegetable oils have soared. Must be the butter. https://t.co/3om0hfVK4i" [X Link](https://x.com/anyuser/status/1734260423484981449) 2023-12-11T17:14Z [----] followers, [----] engagements "Inflation is 1% away from historical target levels (which are malleable in the first place). Driver is rent which the president has minimal to modest control over in terms of driving supply. Structural problems drive these metrics to reflect a good Econ environment" [X Link](https://x.com/ZKForTre/status/1734636942287946211) 2023-12-12T18:10Z [----] followers, [---] engagements "I dont care for Elon at all but can someone tell me why this isnt vindictive and dumb" [X Link](https://x.com/ZKForTre/status/1734951559916638316) 2023-12-13T15:01Z [----] followers, [----] engagements "@DoctorTro It may be worth it to read the trial design before commenting in the future" [X Link](https://x.com/ZKForTre/status/1736047253205250284) 2023-12-16T15:34Z [----] followers, [---] engagements "Now imagine people tried to argue that any of these wasnt the fundamental underwriting principle that everyone was working from" [X Link](https://x.com/ZKForTre/status/1736080738418581996) 2023-12-16T17:47Z [----] followers, [---] engagements "@DavidB50863 Disease in these communities" [X Link](https://x.com/ZKForTre/status/1736466343484944504) 2023-12-17T19:20Z [----] followers, [--] engagements "@DavidB50863 But lets not pretend that such an approach is a panacea. There is ample prescription of these GLP1 drug in affluent and/or economically stable populations and not just for vanity weight loss. If it was only a resources issue the use of these drugs in this population would" [X Link](https://x.com/ZKForTre/status/1736466800936636625) 2023-12-17T19:22Z [----] followers, [--] engagements "Editors note: They replaced SGLt2s with LC *and* a caloric deficit. Weight loss on SGLT2s alone is pretty modest even if metabolic improvements exceed weight loss" [X Link](https://x.com/ZKForTre/status/1736908632019644573) 2023-12-19T00:37Z [----] followers, [----] engagements "Printing money. Thats all smaller and smaller fractions is in practice. Also not for nothing but the dollar is literally the most trusted and democratized store of value in the world. Find a better specter to argue against" [X Link](https://x.com/ZKForTre/status/1737666855425257886) 2023-12-21T02:50Z [----] followers, [---] engagements "Im not going to pretend I watch every 76ers playoff game but is part of the reason his number (and efficiency numbers) tank in the playoff is because they stop giving him a patently absurd whistle" [X Link](https://x.com/ZKForTre/status/1737881680776491054) 2023-12-21T17:04Z [----] followers, [---] engagements "Cholesterol-containing lipoprotein infiltration of the vessel wall is literally the spearhead of the atherosclerotic cascade. Even if one was trying pitch an argument that the role of lipoproteins are over-emphasized this is essentially the selectively worst version" [X Link](https://x.com/ZKForTre/status/1738201473077436920) 2023-12-22T14:15Z [----] followers, [----] engagements "@kunningdruger23 Its a bias towards the confluence of data. Im not in the camp that says its only ApoB as far and away the lone causal risk factor but the evidence of its sentinel role (and its validity as a therapeutic target) has been demonstrated countless times and ways" [X Link](https://x.com/ZKForTre/status/1738300931106619481) 2023-12-22T20:50Z [----] followers, [--] engagements "Why is it always the keto/carnivore crowd that experiences the worlds most asshole-ish doctors is a seemingly selective manner" [X Link](https://x.com/ZKForTre/status/1738301834081501394) 2023-12-22T20:53Z [----] followers, [----] engagements "@Chaddadbod Cutting out an entire food group will make it decidedly less likely and will minimize glucose spikes but total glycemic exposure is dictated by AUC exposure not transient prandial spikes. But youve consumed all the kool aid so this is fruitless" [X Link](https://x.com/ZKForTre/status/1738350154451714207) 2023-12-23T00:05Z [----] followers, [--] engagements "Semaglutides weight loss effects extend well beyond delaying gastric emptying. Ceasing prior to surgery (and associated ileus risk) should be considered and studied" [X Link](https://x.com/ZKForTre/status/1738772333811183628) 2023-12-24T04:03Z [----] followers, [----] engagements "Probably social media apps that feature science influencers and political zealots. If you had to pick only [--] non-negotiable (once you decide) No more ______ for me once in [----] what is that thing behavior thought etc. If you had to pick only [--] non-negotiable (once you decide) No more ______ for me once in [----] what is that thing behavior thought etc" [X Link](https://x.com/ZKForTre/status/1739757656338845857) 2023-12-26T21:18Z [----] followers, [---] engagements "@RosenelliEM @BioLayne I will literally go through Richard Johnson claims one by one if you want. We are departing the realm of real concerns about fructose and departing for mouse megadose extrapolations" [X Link](https://x.com/anyuser/status/1741573520906231876) 2023-12-31T21:34Z [--] followers, [---] engagements "I overcame playing against CeeDee lamb Flacco and Jerome Ford to win this week and its maybe the only meaningful accomplishment I had this year" [X Link](https://x.com/anyuser/status/1741617148487745795) 2024-01-01T00:27Z [--] followers, [---] engagements "@CharlesMBrenner Thats like a week or more for humans. Not that its a linear comparison but it is a looooooooong time without eating for a mouse" [X Link](https://x.com/anyuser/status/1742765356706308173) 2024-01-04T04:30Z [--] followers, [---] engagements "It is interesting to compare these to the reports of malaise/generalized/GI discomfort for individuals on these drugs. As in the two dont seem to line up even if they arent a direct 1:1 comparison 📣New study: semaglutide compared with non-GLP1R agonist anti-obesity medications associated with lower risk for incident (HR = 0.27) and recurrent (HR = 0.44) suicidal ideation consistent across sex age and ethnicity stratification. https://t.co/aBB3kAnKxJ H/t @ChrisPalmerMD 📣New study: semaglutide compared with non-GLP1R agonist anti-obesity medications associated with lower risk for incident (HR" [X Link](https://x.com/ZKForTre/status/1743353113971507299) 2024-01-05T19:25Z [----] followers, [---] engagements "@MichaelMindrum Those reporting long-term mild to moderate nausea with things that used to not produce the same symptoms" [X Link](https://x.com/anyuser/status/1743374805280207243) 2024-01-05T20:51Z [--] followers, [--] engagements "@Gaardsy I mean the Wolves traded [--] picks (3 unprotected) a [----] swap Kessler and others for a [--] footer in his 30s. Hed essentially have to play his contract out at this level to even reach acceptable. Indiana traded [--] of their 1st and next years (probably) OKC pick plus Bruce brown" [X Link](https://x.com/ZKForTre/status/1747723782826217607) 2024-01-17T20:53Z [----] followers, [---] engagements "@DavidB50863 @travelingenes Im fine with improving hospital nutrition broadly but if the argument is that transient meals in hospitals are the breaking point for cancer therapy or nutritional practice I mean thats just not supported in any way" [X Link](https://x.com/ZKForTre/status/1748502703200682055) 2024-01-20T00:28Z [----] followers, [--] engagements "@PowerTripBets Im certainly am in favor of gearing up to to get a QB. But getting to [--] or [--] is going to take the whole farm and Jayden Daniels is a high risk guy. I think one of Nix Penix McCarthy Travis etc will be good but its a roll of the dice and I dont think any are transcendent" [X Link](https://x.com/ZKForTre/status/1749265417409904718) 2024-01-22T02:59Z [----] followers, [---] engagements "1. Less frequent eating doesnt increase ldl per se. Long-term fasting does but thats a unique case. [--]. Weight loss on overweight or obese individuals routinely decreases ldl in the intermediate to long term. This requires hyper fixation on lean individuals 🤔Eating less frequently RAISES LDL ☠Snacking more DECREASES LDL 🤔Lowering carbs RAISES LDL ☠Processed carbs DECREASES LDL 🤔Low BMI RAISES LDL ☠High BMI DECREASES LDL Focusing on LDL while disregarding obesity & metabolic syndrome is MALPRACTICE 🤔Eating less frequently RAISES LDL ☠Snacking more DECREASES LDL 🤔Lowering carbs RAISES LDL" [X Link](https://x.com/ZKForTre/status/1750956744161829036) 2024-01-26T18:59Z [----] followers, [---] engagements "@JonKrawczynski True but its time to go. They have reasonably [--] months to correct what are now a lot of non-trivial concerns on offense and in the playoffs teams will space them out such that it will be harder to have the same defensive advantage" [X Link](https://x.com/ZKForTre/status/1751739999022690687) 2024-01-28T22:52Z [----] followers, [---] engagements "@JonKrawczynski I would agree if not for the fact that the problems that absolutely plagued them last year (including early year with KAT) werent showing back up. Turnovers are A1 and maybe can be fixed but they also have become reliant on isolation possessions especially in the late game" [X Link](https://x.com/ZKForTre/status/1751744761403236390) 2024-01-28T23:11Z [----] followers, [--] engagements "@JonKrawczynski Where they arent very efficient unless Ant is having one of his superhero nights. They struggle with teams that can out [--] shooter in the floor which are OKC Den LAC Pho etc. Conley keeps them settled when hes out there but he cant play [--] minutes/game" [X Link](https://x.com/ZKForTre/status/1751745182498787632) 2024-01-28T23:12Z [----] followers, [--] engagements "This game is a full-fledged treatise on how probability is taught in the American educational system and how Americans do (or more accurately do not) understand variance" [X Link](https://x.com/ZKForTre/status/1751797106484875753) 2024-01-29T02:39Z [----] followers, [---] engagements "@BHBEnjoyer Among others" [X Link](https://x.com/ZKForTre/status/1752718731921313828) 2024-01-31T15:41Z [----] followers, [--] engagements "@BHBEnjoyer Prior to [----] Idk id have to look. Im hardly a fan of convenient timeframes and not sure why it matters" [X Link](https://x.com/ZKForTre/status/1752718986796466497) 2024-01-31T15:42Z [----] followers, [--] engagements "I could unpack this [--] ways to Sunday but Ill leave it at this: In sports it is quite rare to see an outstanding player (elite professional) become a best in class coach. It is much more common to see guys who barely spent time on a roster or came up through the film room. I think its fair to ask if the MD or scientist or public health official saying to do X or not do Y looks and sounds healthy and vital. I avoid going to a dentist with bad teeth. What do you think I sense diverging opinions on this. I think its fair to ask if the MD or scientist or public health official saying to do X or" [X Link](https://x.com/ZKForTre/status/1752829411441754119) 2024-01-31T23:01Z [----] followers, [----] engagements "@GeorgiaEdeMD So they are making a common mistake here assuming their 60-70% claim is accurate (it would be essentially the highest suggested by any group and should be validated and published) LBM cannot be equated to muscle mass directly. There are a number of sources of lean mass" [X Link](https://x.com/ZKForTre/status/1754203573041143867) 2024-02-04T18:01Z [----] followers, [---] engagements "@GeorgiaEdeMD Including organ weights which would be expected to decline with corresponding weight loss. Further data on loss of muscle strength has been much more modest even in the presence of (not half) confirmed muscle loss" [X Link](https://x.com/ZKForTre/status/1754204042295738654) 2024-02-04T18:03Z [----] followers, [--] engagements "@GeorgiaEdeMD Further still the side effects noted are overwhelmingly nausea and GI side effects that lessen over time. And while they may try to suggest that 70% come off them within a year thats largely due time accessibility and affordability" [X Link](https://x.com/ZKForTre/status/1754204573424644123) 2024-02-04T18:05Z [----] followers, [--] engagements "@GeorgiaEdeMD Moreover if they are accurate in that they were treating patients with Ozempic for glycemia management they werent even utilizing it for a weight loss indication. If they were they were utilizing it off label or just substituting Ozempic for WeGovy. This is before" [X Link](https://x.com/ZKForTre/status/1754205103068741664) 2024-02-04T18:07Z [----] followers, [--] engagements "@GeorgiaEdeMD We would even talk about them using tirzepatide which appears to result in less lean mass loss overall (relevance tbd)" [X Link](https://x.com/ZKForTre/status/1754205257679151356) 2024-02-04T18:08Z [----] followers, [--] engagements "@GeorgiaEdeMD As for there ability to sustain GLP1-induced weight loss its not uncommon for weight loss to be sustained for a year with intensive clinical intervention (theyve published their own data that presumably reinforces this concept)but they also show regression past this timepoint" [X Link](https://x.com/ZKForTre/status/1754206371845710158) 2024-02-04T18:12Z [----] followers, [--] engagements "@GeorgiaEdeMD So Im not really sure what relevance theyre claiming this has outside of trying to denigrate the drugs. There are real problems with the utilization of these drugs. The need to hand wave false flag concerns is totally unnecessary and makes one wonder about motivations" [X Link](https://x.com/ZKForTre/status/1754206792144359429) 2024-02-04T18:14Z [----] followers, [--] engagements "Its hard to exaggerate how bad this logic is. Treatments with high efficacy have no obligation to be the core driver of the development of the pathology. See melanoma and checkpoint inhibitors as perhaps the best example. There arent enough facepalm emojis for this rationale Obesity is not an Ozempic deficiency. Heart disease is not a statin deficiency. Diabetes is not a metformin deficiency. Depression is not an SSRI deficiency. ADHD is not an Adderall deficiency. Were being lied to. Obesity is not an Ozempic deficiency. Heart disease is not a statin deficiency. Diabetes is not a metformin" [X Link](https://x.com/ZKForTre/status/1755109913162854502) 2024-02-07T06:03Z [----] followers, [----] engagements "Dictators and authoritarians across the hemispheric north love Tucker Carlson and the American right needs their forum from which to lap it up. @elonmusk please confirm I hope X has enough server capacity for when this interview drops. @elonmusk please confirm I hope X has enough server capacity for when this interview drops. @elonmusk please confirm" [X Link](https://x.com/ZKForTre/status/1755113543374868555) 2024-02-07T06:17Z [----] followers, [---] engagements "@Justinredalen @elonmusk [--] million is n cable news is massive. His videos on Twitter get millions to tens of millions of views. He gets lots of YouTube traction beyond this. But okay" [X Link](https://x.com/ZKForTre/status/1755117392252825865) 2024-02-07T06:32Z [----] followers, [--] engagements "@fellowshipnate @hammerotass Safety record is extremely good. Weve covered recidivism muscle loss (exaggerated as it is) can be mitigated. Look I get you are incentivized to be against these drugs on multiple levels but stick to empirically supported arguments against them at minimum" [X Link](https://x.com/ZKForTre/status/1755357739318964244) 2024-02-07T22:27Z [----] followers, [--] engagements "@fellowshipnate @hammerotass @pfizer Also you have but to simply google why the [--] years of cover (it actually wasnt [--] but you do you) as a prevention from getting sued is a comically dumb argument but weve already demonstrated that youre unwilling to google to help your case so 🤷♂" [X Link](https://x.com/ZKForTre/status/1755639301889556809) 2024-02-08T17:06Z [----] followers, [--] engagements "@fellowshipnate @hammerotass @pfizer I will again ask you to pick a specific point in which you would like to defend empirically. You can pick literally any of them. Weve established that you have a strong fear of any level of institutional authority such that you dont even trust randomized controlled trials" [X Link](https://x.com/ZKForTre/status/1756018453994152148) 2024-02-09T18:13Z [----] followers, [--] engagements "Do people that are calling Tucker an American hero (real thing not an exaggeration) want to go ahead and mention that he was literally hand-picked by the Kremlin for his pro-Russian and authoritarian-tolerant positions" [X Link](https://x.com/ZKForTre/status/1756032837885501564) 2024-02-09T19:10Z [----] followers, [---] engagements "@Mark_C_Casper We could go through his commentary and leave it open to individual interpretation but the Kremlin phrased it has having ideas that differed from the main contingent of American journalistic outlets. Which one can interpret however you want coming from the Kremlin" [X Link](https://x.com/ZKForTre/status/1756043855558783473) 2024-02-09T19:54Z [----] followers, [--] engagements "@Mark_C_Casper Nope I very clearly laid out the context here. Spin to your leisure I didnt leave much ambiguity" [X Link](https://x.com/ZKForTre/status/1756072573308137858) 2024-02-09T21:48Z [----] followers, [--] engagements "@Mark_C_Casper And I very clearly delineated that this was not based on being a mouthpiece for the administration. Its based on pro-Russia rhetoric over and over and over again. Its really not tough" [X Link](https://x.com/ZKForTre/status/1756073591941001264) 2024-02-09T21:52Z [----] followers, [--] engagements "@Mark_C_Casper I defined pro-Russia as be pro-Russia because the implication is self evident. This isnt complicated nor was it intended to be" [X Link](https://x.com/ZKForTre/status/1756105473210642816) 2024-02-09T23:59Z [----] followers, [--] engagements "@AndrewYang He lost to Marianne Williamson dude. You cant claim to be existentially concerned about electability and be touting Mr. Phillips (and I say this as someone who thinks Phillips is fairly compelling on the whole)" [X Link](https://x.com/ZKForTre/status/1756408326122770689) 2024-02-10T20:02Z [----] followers, [---] engagements "Editors note: its an assault weapons ban. That noted communist Bill Clinton passed one nationally in [----] The radical Communist Democrats of Minnesota just introduced a bill to ban certain types of rifles and institute a buyback program. This is what happens when you elect crazy activists to office and have complete rule over an entire state government. https://t.co/uzAXU7FP0m The radical Communist Democrats of Minnesota just introduced a bill to ban certain types of rifles and institute a buyback program. This is what happens when you elect crazy activists to office and have complete rule" [X Link](https://x.com/ZKForTre/status/1756682321518907423) 2024-02-11T14:11Z [----] followers, [---] engagements "@MichaelAlbertMD I mean thats fairly hard to argue definitely from their data. The period of reduced food intake was longer than the window in which there was active weight loss of a demonstrably lower weight gain trajectory in either sex" [X Link](https://x.com/ZKForTre/status/1756770443233542538) 2024-02-11T20:01Z [----] followers, [--] engagements "Introducing Rogans core audience These white kids havent been indoctrinated in the least. Nope. https://t.co/Lls8Jyzzeg These white kids havent been indoctrinated in the least. Nope. https://t.co/Lls8Jyzzeg" [X Link](https://x.com/ZKForTre/status/1756895100813156498) 2024-02-12T04:16Z [----] followers, [----] engagements "@elonmusk Im sure youre ready to endorse a modern tax structure that would tax you more to raise revenues to pay the interest/pay it down" [X Link](https://x.com/ZKForTre/status/1757190177380819147) 2024-02-12T23:49Z [----] followers, [--] engagements "@RPLongSW @elonmusk So this is actually a longer conversation. It is generally considered to decrease private investment (although that data is much noisier than older Econ would say). It can and has spurred public investment throughout the 1900s" [X Link](https://x.com/ZKForTre/status/1757197817674637418) 2024-02-13T00:19Z [----] followers, [--] engagements "@RPLongSW @elonmusk This is empirically false. I can pull the data when I get home" [X Link](https://x.com/ZKForTre/status/1757201044344303944) 2024-02-13T00:32Z [----] followers, [--] engagements "Here is the ingredient list for McDonalds pickles. 7/10 are ingredients for pickled cucumbers. [--] are preservatives that are well studied and safe in humans. The last is color. But cool story bro. This is CRAZY 😳 @McDonalds pickles contain [--] ingredients Over 60% of our calories come from processed foods today and I believe they are the biggest driver of chronic diseases. Ditch the processed foods and eat REAL foods https://t.co/MMe8nzAHpo This is CRAZY 😳 @McDonalds pickles contain [--] ingredients Over 60% of our calories come from processed foods today and I believe they are the biggest" [X Link](https://x.com/ZKForTre/status/1757235734648435001) 2024-02-13T02:50Z [----] followers, [----] engagements "@RobertKennedyJr I honestly cannot comprehend how any rationale actor would assess support for Ukraine and Taiwan specifically as anything short of morally correct not to mention outstanding foreign policy from just a net investment perspective" [X Link](https://x.com/ZKForTre/status/1757274963990479319) 2024-02-13T05:26Z [----] followers, [---] engagements "1. They have (arguably rightly) declared martial law which prohibit elections. Also Ukrainians dont want to have elections based on polling. [--]. This really papers of the Lira story as a political murder. Probably google the details on that. Tuckers definitely not pro-Russia BREAKING: Tucker Carlson says Ukraine shouldn't receive any more funds after canceling their elections and kiIIing an American journalist. Do you agree https://t.co/W5J2i8e7Tu BREAKING: Tucker Carlson says Ukraine shouldn't receive any more funds after canceling their elections and kiIIing an American journalist. Do you" [X Link](https://x.com/ZKForTre/status/1757283105621111281) 2024-02-13T05:58Z [----] followers, [---] engagements "@Mark_C_Casper They pushed off a full-scale takeover of at minimum the Donbas region. Russian military has regrouped after suffering major setbacks in the first phase of the war and has a larger fighting force but they are still primarily fighting as in invasion force" [X Link](https://x.com/ZKForTre/status/1757296780071366958) 2024-02-13T06:52Z [----] followers, [--] engagements "@MichaelMindrum @AKoutnik @BenBikmanPhD True but I am rather specifically noting in this case that ingestion and infusion of lipid causes a transient insulin resistance namely at the level of skeletal muscle. This may be evolutionarily tied to meal partitioning or fasting mobilization hard to say" [X Link](https://x.com/ZKForTre/status/1758354531128132079) 2024-02-16T04:56Z [----] followers, [---] engagements "@AKoutnik @UKLowCarb @BenBikmanPhD @Gonzalez_JT Dont think I am arguing this. Im very specifically arguing that there is a transient increase in muscle insulin resistance that may be somewhat sustained under chronically elevated FFA conditions. If there isnt any glucose intake or GSIS it may not matter much" [X Link](https://x.com/ZKForTre/status/1758588667268849911) 2024-02-16T20:26Z [----] followers, [--] engagements "@sdskol1983 Can you point to a professional sports franchise who has opened their books outside of the Packers reporting limited financial information required due to public ownership" [X Link](https://x.com/ZKForTre/status/1760401260719538685) 2024-02-21T20:29Z [----] followers, [--] engagements "Antivaxers: the CDC was wrong about everything. CDC issues new guidance saying its fine to do stuff while still infectious. Antivaxers: see we were right the whole time If you got vaccinated just admit you got scammed If you got vaccinated just admit you got scammed" [X Link](https://x.com/ZKForTre/status/1764158422218387627) 2024-03-03T05:18Z [----] followers, [---] engagements "@WallStreetSilv How do Twitters ad revenue since Elon bought it" [X Link](https://x.com/ZKForTre/status/1764605370104692975) 2024-03-04T10:54Z [----] followers, [--] engagements "Stop trying to make strain-specific boosters into something scary. Weve been doing it for the flu for decades. CDC now says they can stay one step ahead of a virus that's always changing. So now they can predict new mutations and when it will occur This is lunacy #vaccinesafety CDC now says they can stay one step ahead of a virus that's always changing. So now they can predict new mutations and when it will occur This is lunacy #vaccinesafety" [X Link](https://x.com/ZKForTre/status/1765582177050243493) 2024-03-07T03:36Z [----] followers, [---] engagements "@RobertKennedyJc Damn I fell for the parody account. Im better than this" [X Link](https://x.com/ZKForTre/status/1765582828811546997) 2024-03-07T03:38Z [----] followers, [--] engagements "@Justinredalen @ClayTravis I already stated that it is of no import if you want to compared red to red blue to blue or a mix. Id make the exact same argument regarding. The impacts are only so exaggerated in such a hyper-partisan decelerationist legislative body" [X Link](https://x.com/ZKForTre/status/1765853058653663595) 2024-03-07T21:32Z [----] followers, [--] engagements "@Justinredalen @ClayTravis It objectively doesnt. Its a broad hand wave to eschew actual scholarship in reporting rates for undocumented individuals which universally points to them being undercounted (for obvious and non-obvious reasons)" [X Link](https://x.com/ZKForTre/status/1766311577085424013) 2024-03-09T03:54Z [----] followers, [--] engagements "@Justinredalen @ClayTravis This same story happens for citizens at a far higher frequency according to every crime analysis This is devolving into a bad Fox News segment. Please do better or stop wasting time" [X Link](https://x.com/ZKForTre/status/1766332087592722573) 2024-03-09T05:16Z [----] followers, [--] engagements "@TomCottonAR @KatieBrittforAL They are attacking her because her chosen stock example was an event that occurred in Mexico during the Bush [--] administration. That alongside her Laken Riley response which clearly was changed last minute as she didnt expect Biden to mention her. Its okay to admit it was bad" [X Link](https://x.com/ZKForTre/status/1766770213318431021) 2024-03-10T10:16Z [----] followers, [--] engagements "Pay the toll this year draft your rookie QB (Drake Maye) come back with tons of ammo this time next year. #Vikings are now the league leader in dead money at $57.3M. Packers at number [--] at $46.5M. Seahawks are 3rd at $36M #Vikings are now the league leader in dead money at $57.3M. Packers at number [--] at $46.5M. Seahawks are 3rd at $36M" [X Link](https://x.com/ZKForTre/status/1767708271693992085) 2024-03-13T00:24Z [----] followers, [---] engagements "Lots of commentary that the Vikings are going to move to 4-8 and draft McCarthy and the cost of [--] firsts and a kicker. QBs should be considered on their own merits but here are the 4th QBs taken in recent years: 2023: Will Levis 2022: Matt Corral 2021: Justin Fields" [X Link](https://x.com/ZKForTre/status/1768855426051793259) 2024-03-16T04:22Z [----] followers, [---] engagements Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing
@ZKForTre 🐊ZK For Tre🐊🐊ZK For Tre🐊 posts on X about in the, health, this is, if you the most. They currently have [-----] followers and [----] posts still getting attention that total [------] engagements in the last [--] hours.
Social category influence finance technology brands countries celebrities stocks us election social networks cryptocurrencies travel destinations automotive brands
Social topic influence in the, health, this is, if you, money, elon musk, study, tre #949, rfk, weight loss
Top accounts mentioned or mentioned by @sirajahashmi @ewarren @gugahimself @northflsparky @honestballfan13 @elonmusk @doctortro @alexjleaf @biolayne @fellowshipnate @nacholeber @theproof @skl2433 @drmuniyappa @justinredalen @michaelmindrum @carnivoreaureli @emarksalot @robertkennedyjr @raphaels7
Top assets mentioned GLP1 (GLP1) Alphabet Inc Class A (GOOGL) Bitcoin (BTC) Tesla, Inc. (TSLA)
Top posts by engagements in the last [--] hours
"Fox News voters consistently rank as the least informed and most factually inaccurate voters and individuals among news watchers. Forgive me if I dont care about this stupid attempt to shame CNN. LOL @CNN just interviewed a random person at the Gillum rally who said Obamas presence helped influence her vote and it turned out she was Gillums mom. 😑 LOL @CNN just interviewed a random person at the Gillum rally who said Obamas presence helped influence her vote and it turned out she was Gillums mom. 😑"
X Link 2018-11-04T04:33Z [----] followers, [--] engagements
"There is no more paranoid group on the internet (well short of flat earthers) than the LC/Keto/Carnivore evangelists. Id say get to get a hobby to fill the time but internet evangelizing is probably taking up a lot of that time. Heh-heh . looks like "Fat Head" is the next target of @Wikipedia's Soviet-style cleansing of the historical record. (You see comrades we cannot allow the proletariat to be confused by entries about people and films that actually exist but question the party's principles.) Heh-heh . looks like "Fat Head" is the next target of @Wikipedia's Soviet-style cleansing of the"
X Link 2018-12-20T18:35Z [----] followers, [--] engagements
"@Kitt_S_N_Koola @The_Nutrivore @snoosphere @DaveKeto @TuckerGoodrich It doesnt get shut down. Statins are competitive inhibitors and dosed to reduce not eliminate. Eliminating would mean death. Cells still get sufficient lipids they just upregulation the amount that come from circulation"
X Link 2019-12-18T23:23Z [----] followers, [--] engagements
"For once hoping for sulphoraphane and HSPs if/when i get to it. Please please not Vit D =/= COVID. Please. Some incredibly important information on the podcast today from the great and powerful @foundmyfitness Dr Rhonda Patrick is one of my all time favorite guests and absolutely one of the most brilliant people I know. https://t.co/fy69KiZMIN Some incredibly important information on the podcast today from the great and powerful @foundmyfitness Dr Rhonda Patrick is one of my all time favorite guests and absolutely one of the most brilliant people I know. https://t.co/fy69KiZMIN"
X Link 2020-05-14T19:46Z [----] followers, [--] engagements
"@DaveKeto @siobhan_huggins Not to be a wet blanket but b-cell phagocytosis and self antigen presentation represents quite a small subset of b-cell/lympocyte activation. The co-stimulatory signals provided by APCs massively increase proliferation and response as well. Absolutely a cool mechanism though"
X Link 2020-05-18T23:50Z [----] followers, [--] engagements
"@DaveKeto @siobhan_huggins driven expansion too. Again just hard to take the methods used in the paper and call it representative. In clonal expansions of B-cells (like a culture) (as in germinal centers) co-stimulation by t-cells APCs and cytokines has occurred. If working as APC less so"
X Link 2020-05-19T01:35Z [----] followers, [--] engagements
"The United States in [----] described in one tweet. Americans have been consistently very wrong. https://t.co/7bcCtwcYJz https://t.co/v5GjSWHfe7 Americans have been consistently very wrong. https://t.co/7bcCtwcYJz https://t.co/v5GjSWHfe7"
X Link 2020-08-08T17:40Z [----] followers, [--] engagements
"Having GameStop the first week in august is now worth more than having Bitcoin at $1000"
X Link 2021-01-26T18:42Z [----] followers, [--] engagements
"@Chrest_brett Combining genetics and metabolic targets for individual tumors holds the key if I were to guess. Not for initial treatment but for recurrence or eliminating cancer stem cells"
X Link 2022-05-02T05:46Z [----] followers, [--] engagements
"Using the structure of this graphic a bowl of cheerios a protein shake and a fish oil is just about the healthiest thing one can consume. Stupid games stupid prizes. Imagine thinking that Red Meat is bad for you. https://t.co/2UZEAjIYti Imagine thinking that Red Meat is bad for you. https://t.co/2UZEAjIYti"
X Link 2022-10-04T06:36Z [----] followers, [--] engagements
"Free speech absolutist until it negatively impacts me. Any account doxxing real-time location info of anyone will be suspended as it is a physical safety violation. This includes posting links to sites with real-time location info. Posting locations someone traveled to on a slightly delayed basis isnt a safety problem so is ok. Any account doxxing real-time location info of anyone will be suspended as it is a physical safety violation. This includes posting links to sites with real-time location info. Posting locations someone traveled to on a slightly delayed basis isnt a safety problem so"
X Link 2022-12-15T00:35Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 Had your argument been absolutely hardline including a rejection of legacy admissions I could have at least acknowledged the case but now were are kind of just pulling from all sides haha"
X Link 2023-06-30T02:12Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 I think I can illustrate the point in [--] simple questions. [--]. For the majority of the lifespan on affirmative action laws (we can talk about recent caveats at the end of you want) do you believe/agree that a college degree was a strong stool of upward mobility in this country"
X Link 2023-06-30T02:14Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 If you mean in the last 10-20 years then fine. These were the caveats I was talking about driven mostly by rapid price escalation. Before that (and to a less extent now) we can agree that data fairly convincingly shows upward mobility for college graduates"
X Link 2023-06-30T02:24Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 I mean there is strong evidence that just isnt true at least at Harvard"
X Link 2023-06-30T02:29Z [--] followers, [--] engagements
"@AlexJLeaf @SKl2433 I am of the opinion that the majority of people in this country arent that different in terms of raw horsepower. So then the mostly reasonable interpretation here is that some kids were born into harder circumstances and did the same the kids that were born into"
X Link 2023-06-30T02:53Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 Better circumstances would have done in the same spot. Then we propagated that difference via social and even legislative forces for decades such that the gap in circumstances became quite significant at the population level"
X Link 2023-06-30T02:50Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 What affirmative action policies did then is took some of the kids that performed the same as the kids in the good circumstance if you adjust for circumstances. Its not razor-precise but it does increase the opportunity for mobility of people who were"
X Link 2023-06-30T02:52Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 But it remains an instrument to take a certain percentage of members of marginalized communities and enable them to have the same upward mobility tool. They are also more likely to reinvest that capital in their communities that an alternative candidate would be"
X Link 2023-06-30T02:58Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 From a summative article: The study published earlier this month in the National Bureau of Economic Research found that [--] percent of white students admitted to Harvard University were recruited athletes legacy students children of faculty and staff"
X Link 2023-06-30T03:00Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 Im struggling to appreciate any interpretation in which these arent in all but letter of the law exactly the same thing"
X Link 2023-06-30T03:12Z [----] followers, [--] engagements
"@AlexJLeaf @SKl2433 Like at best this is being okay with a passive version of the activity but being against an active one that was initially implemented to combat the passive version"
X Link 2023-06-30T03:12Z [--] followers, [--] engagements
"@DudzLightLime @dr_muniyappa @Drlipid @MattBMartin The former is my understanding for sure. I think Shulman among others has put a nice bow on that story But if thats the case how is a relatively stable hypoglycemia achieved in genetic conditions The normal arrows that drive glucose control get mixed at least a bit right"
X Link 2023-06-30T03:16Z [----] followers, [--] engagements
"@DudzLightLime @dr_muniyappa @Drlipid @MattBMartin No no I hope I dont start asking question that sense haha. I meant more than in the context that primary hyperinsulinemia drives some degree of IR (as some believe is relevant even in T2DM pathogenesis) how does this integrate into initial glycemia regulations"
X Link 2023-06-30T03:23Z [----] followers, [--] engagements
"This individual is approaching half a million followers in case you were wondering where the quality of discourse is at"
X Link 2023-07-09T02:20Z [----] followers, [----] engagements
"@Chrest_brett Cancer mitochondria probably not as dysfunctional as once presumed"
X Link 2023-07-11T00:32Z [----] followers, [---] engagements
"I do think the rebuttal questions do have to be more inciting in cases like this but I also dont know the challenges of quarterbacking such a show"
X Link 2023-07-11T02:28Z [----] followers, [---] engagements
"Now do glucose. Cholesterol is essential https://t.co/8Lb1yh2IMQ Cholesterol is essential https://t.co/8Lb1yh2IMQ"
X Link 2023-08-16T18:24Z [----] followers, [----] engagements
"@TheNutrivore I get a kick out people who claim to have optimal metabolic health being entirely destroyed by a couple of grams of added PUFA"
X Link 2023-08-20T21:54Z [----] followers, [----] engagements
"I posted my lowest lifetime A1c (4.8) despite having more carbs and a lower diet qualify overall (still good but more garbage in total) in recent months. Go figure"
X Link 2023-08-22T17:54Z [----] followers, [----] engagements
"@gerdosi @MJ18912000 Its pretty conclusive though. Maybe there will be a strong signal in the future (though the plausibility of that kind of lag time is highly questionable) but it hasnt materialized. Obviously if it does that is need-to-know information"
X Link 2023-08-23T15:26Z [----] followers, [--] engagements
"No one argues that obesity is as simple as counting calories these days. This is a straw man. What the argument actually is is that caloric balance is the inescapable underwriting principle that determines weight balance. Many strategies are in service of that target"
X Link 2023-08-24T15:31Z [----] followers, [----] engagements
"Very little evidence that glyphosate at human exposure levels does much of anything. Glyphosate is so harmful for humans. And its sprayed all over your oatmeal Organic oats arent that much better see the threads https://t.co/iXBfnTbVwW Glyphosate is so harmful for humans. And its sprayed all over your oatmeal Organic oats arent that much better see the threads https://t.co/iXBfnTbVwW"
X Link 2023-08-24T22:07Z [----] followers, [----] engagements
"@ketogrillbakery @nicknorwitz @davidludwigmd @AdrianSotoMota @DoctorTro I cannot emphasize beyond this last time that this is addressed in the article. Very early in it in fact. This constant rewinding is becoming frivolous"
X Link 2023-08-25T18:36Z [----] followers, [--] engagements
"@ketogrillbakery @ESpacetime @DoctorTro So let me drill down to brass tax here. You are parroting Nick who is partying Adrian. About right"
X Link 2023-08-25T18:52Z [----] followers, [--] engagements
"@TheNutrivore He is a serial reflexive blocker. The irony here is palpable"
X Link 2023-08-27T16:45Z [----] followers, [---] engagements
"@VigilantFox @joerogan He left because of taxes. It was taxes. My goodness"
X Link 2023-09-03T01:19Z [----] followers, [----] engagements
"@Rickyg668620362 @VigilantFox @joerogan It literally would be the 5th or 6th largest economy in the world if it were its own country. But sure economically and financially unsustainable"
X Link 2023-09-03T03:45Z [----] followers, [--] engagements
"@Rickyg668620362 @VigilantFox @joerogan The business of homelessness. Ive rarely heard such an esoteric suggestion of net profitability. You havent even touched on a top [--] industry in California. Ill let you try again if you want"
X Link 2023-09-03T04:11Z [----] followers, [--] engagements
"@Rickyg668620362 @VigilantFox @joerogan There are literally economic statistics that are easily google-able. California is a net contributor. Im going to need you to try to reference some actual datasets and not whatever hyper-politicized fever dreams youve been listening to"
X Link 2023-09-03T04:15Z [----] followers, [--] engagements
"@dbechek1 @GeoffreyStreve1 @EricRWeinstein You do realize though that it is what established prices during a period or record inflation right Those prices dont now go down. Nor are those profits solely from retailers. Consumption has continued to rise even in spite of inflated prices"
X Link 2023-09-03T14:07Z [----] followers, [--] engagements
"@dbechek1 @GeoffreyStreve1 @EricRWeinstein Moreover estimate levels of inflation that were contributed by corporate price hikes was between [--] and 60% higher by any metric that fiscal stimulus or even supply chain breakdowns in isolation. Record quarterly profits were being realized in the Same inflationary environment"
X Link 2023-09-03T14:19Z [----] followers, [--] engagements
"@dbechek1 @GeoffreyStreve1 @EricRWeinstein It is so funny to hear you claim a high ground now [--]. I am literally just echoing the conclusions of multiple economists [--]. You were the one who went on and on and on about fiscal stimulus being the cause of inflation (I can pull up there tweets) and that the USs stimulus"
X Link 2023-09-03T17:16Z [----] followers, [--] engagements
"@Justinredalen There is literally more evidence they work in an individual basis than a population basis. See above. Also they cannot work on a population basis if they do not work in an individual basis. Whatever"
X Link 2023-09-04T15:35Z [----] followers, [--] engagements
"@Jodie_Boisvert It will come back in time. Not for the material you read regularly but for other topics. If you want a bridge audiobooks can kind of ease you back into reading without actually having to look at more text"
X Link 2023-09-04T18:11Z [----] followers, [--] engagements
"@ScepticalDoctor @DudzLightLime @PlantChompers Also saying ldl/ApoB rises because of fat adaptation is a physiological tautology and is a good example of the imprecise language being derided the tweet prior"
X Link 2023-09-04T18:39Z [----] followers, [---] engagements
"@ScepticalDoctor @DudzLightLime @PlantChompers Bottom line people with low levels of insulin resistance are going to be at less risk of ascvd endpoints because IR is either a causal risk factor and/or an iterative variable on ApoB. Individuals with low ApoC3 (usually invoked as a proxy of low trigs and remnants by the low"
X Link 2023-09-04T18:42Z [----] followers, [--] engagements
"@ScepticalDoctor @DudzLightLime @PlantChompers If their LDL is [---] and they have good glycemic control and low insulin their whole (adult) life would their increased risk be especially high Idk for sure maybe not. Would it be higher than if there ldl was [--] Almost all evidence says yes"
X Link 2023-09-04T19:23Z [----] followers, [--] engagements
"@ScepticalDoctor @DudzLightLime @PlantChompers People are free to make their conclusions from there. Even if they didnt want to take a statin just taking Zetia would be a decent buffer for people going down this road. [--] of rosuvastatin and low dose zetia would give them the best of both 🤷♂"
X Link 2023-09-04T19:25Z [----] followers, [--] engagements
"@MakaiOokami @DoctorTro [--]. Non-sequitur [--]. The evidence that reductions in sugar intakes meaningfully improves AD(H)D is shockingly poor"
X Link 2023-09-05T02:23Z [----] followers, [--] engagements
"I re-amazed almost every week by how so many on this app specifically have been able to monetize or derive social capital from claiming completely invented persecution. Its always from those who claim to be rebellious free thinkers which these days might not mean much"
X Link 2023-09-09T21:47Z [----] followers, [----] engagements
"Or you know just prefers something different than you. Everyone who says strip has been brainwashed and/or bullied by their cardiologist into fearing fat and cholesterol. Everyone who says strip has been brainwashed and/or bullied by their cardiologist into fearing fat and cholesterol"
X Link 2023-09-10T02:37Z [----] followers, [---] engagements
"@CaloriesProper Doesnt his wife also sell keto baking mixes or something"
X Link 2023-09-10T04:26Z [----] followers, [--] engagements
"@Timcast Imagine in the morass of what you regularly defend or explain away identifying this endeavor as evil"
X Link 2023-09-15T21:43Z [----] followers, [--] engagements
"Nope. Still a calorie problem. Thanks for the thought though"
X Link 2023-09-17T17:01Z [----] followers, [----] engagements
"I can imagine few things Im less interested in than Hubermans take on seed oils/PUFAs"
X Link 2023-09-19T20:53Z [----] followers, [----] engagements
"@fire_bottle RCTs with hard outcomes on a nutrient is virtually impossible to conduct or fund in the modern day. The old ones that tried almost universally had brutal flaws. You are left to conduct shorter studies and then extrapolate which people are terrible at"
X Link 2023-09-22T06:57Z [----] followers, [--] engagements
"We live in the dumbest timeline"
X Link 2023-09-22T08:45Z [----] followers, [---] engagements
"To the whole keto/carnivore crowd you are very very fond of claiming your voice is suppressed at various levels. Youll have to explain the following to me then: Dave Feldman: blocked me have repeated offered to discuss/debate all rejected aside from offering to have a beer"
X Link 2023-09-24T21:20Z [----] followers, [----] engagements
"Ivor Cummins: blocked after constant attempts to get him to answer basic methodological questions (I realize hes now moved on to COVID grifts and such now) Ketocarnivore gal: pushed back on her various extrapolations especially regarding mental health instant block"
X Link 2023-09-24T21:20Z [----] followers, [---] engagements
"Your gut health will be much better supported by a generally healthy dietary pattern than from consuming lactations as an adult that are meant to bridge an infant mammal during the earliest stages of post-natal development"
X Link 2023-09-26T22:05Z [----] followers, [----] engagements
"Worlds richest man and purported super genius unwilling or unable to google vaccine efficacy calculation"
X Link 2023-09-27T00:12Z [----] followers, [---] engagements
"@JimJohnsonSci @mario_kratz Im going to hold off on wasting your time asking about the details until Ive had time to dive more into this literature"
X Link 2023-09-27T21:40Z [----] followers, [--] engagements
"This is the football contract equivalent of offering an RB2 and a WR2 for a blue chip player. His open market value is like 50% higher than this minimum. This offer is insulting (and Im lukewarm on Kirk at best)"
X Link 2023-09-30T21:02Z [----] followers, [---] engagements
"Not trying to rip the explanation given as to the sales pitch its actually pretty transparent. I just cant even imagine his agent running it by him given that number. Id try 3/$80 and expect a sizable counter"
X Link 2023-09-30T21:03Z [----] followers, [--] engagements
"@KevinH_PhD Sorry probably shouldnt have tagged you. Its not apples-to-apples but Im referring to this. The paradigms are definitely not the same should have been more careful With the characterization"
X Link 2023-10-17T17:33Z [----] followers, [---] engagements
"@AlexMicheletti Im starting to worry about him (or maybe his dad). Now hes saying he wants an ownership stake in whatever teams drafts him (if I read correctly)"
X Link 2023-10-22T04:45Z [----] followers, [---] engagements
"@anymanfitness But the job/employment environment does contribute to that. With relative wage deflation at its current level the ability to live within that kind of radius for employment is a lot lower especially in bigger cities"
X Link 2023-10-25T23:23Z [----] followers, [---] engagements
"@fellowshipnate @CarnivoreAureli @BioLayne @EMarksalot 31**. Sorry for the typographical error"
X Link 2023-10-27T03:18Z [----] followers, [---] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot Suggesting that within-individual changes with a co-occurring psych intervention is a placebo is patently false btw"
X Link 2023-10-27T03:35Z [----] followers, [---] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot Therapeutic value in epilepsy is seen for a subset of seizure disorders. Im not arguing thats not the case. But its universality for seizure is a matter of serious debate and the extrapolability to non-seizure disorders is essentially null"
X Link 2023-10-27T03:46Z [----] followers, [--] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot The latter comments are of course frankly nonsense"
X Link 2023-10-27T03:46Z [--] followers, [--] engagements
"@fellowshipnate @CarnivoreAureli @BioLayne @EMarksalot Idk if you guys know this but schizophrenia (what was initially invoked) is not a seizure disorder"
X Link 2023-10-27T03:48Z [----] followers, [--] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot You realize this objection means nothing right"
X Link 2023-10-27T03:49Z [----] followers, [--] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot So let me square this you pivot from schizophrenia to epilepsy at a whim then get worked up when I note that the therapeutic value of ketones (BHB) in seizure disorders may not be universal Neat. Neat"
X Link 2023-10-27T03:50Z [----] followers, [--] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot That fine just so long as you acknowledge that a baseless comment of as much is entirely meaningless"
X Link 2023-10-27T03:52Z [----] followers, [--] engagements
"@CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot A nebulous term for someone arguing for nebulous endpoints. But sure"
X Link 2023-10-27T03:53Z [----] followers, [--] engagements
"@LochNessDragon @CarnivoreAureli @fellowshipnate @BioLayne @EMarksalot Wrong carnivore Aurelius my man. This one has like [--] followers. I got duped too"
X Link 2023-10-29T01:58Z [----] followers, [--] engagements
"I dont know that Ive ever understood a move less than this one"
X Link 2023-10-31T18:10Z [----] followers, [---] engagements
"@AlexMicheletti Im convinced there is a cultural movement in Brazil that just involves getting AI to do crazy but themed stuff"
X Link 2023-11-02T05:18Z [----] followers, [---] engagements
"@galaxysplain This conversation has become such an abstraction that Im not even sure what is being discussed anymore. Should I mute the exchange or can we land on a common point of discussion"
X Link 2023-11-06T02:26Z [----] followers, [--] engagements
"@jpegan10 @TheSens1990 @DoctorTro I havent had it measured in years. My last A1c was [---]. Likely given my genetically low LDL my fasting insulin would run slightly higher. But it was [---] last it was measured if I remember correctly. Happy to track it as well if I do this project"
X Link 2023-11-07T20:34Z [----] followers, [--] engagements
"@ZsoltNagy7 @DoctorTro You are now hard pivoting from predictions that would be directly made from the conservation of mass principles. I suspected you didnt actually believe it and now weve illustrated you dont. Thanks for playing"
X Link 2023-11-10T22:40Z [----] followers, [--] engagements
"@ZsoltNagy7 @DoctorTro In an isocaloric setting when consuming relatively more carbs. Net fat mass comes down to you guessed it overall energy balance. Weve come full circle Im so glad you lead us right to the biochemical principle underwriting adipose flux"
X Link 2023-11-10T22:42Z [----] followers, [--] engagements
"@ZsoltNagy7 @DoctorTro Also this paper is about dichotomous energy system switching during exercise used to float an unnecessarily dichotomous view of how energy systems function during exercise"
X Link 2023-11-10T23:27Z [----] followers, [--] engagements
"This is such a willfully poor attempt at critiquing SELECT that is makes me wonder if he A) has shorted Novos stock at some point B) just doesnt especially appreciate trial design C) does appreciate the totality of evidence or the ability to correct for a variable (weight)"
X Link 2023-11-19T15:25Z [----] followers, 16.2K engagements
"He (and a co-author) essentially spend most of an article setting up an argument thats says yeah this is huge effect size but they didnt have a weight-loss matched control. First of all who cares They had a placebo group to compare event rates to and thats the"
X Link 2023-11-19T15:25Z [----] followers, [---] engagements
"Important takeaway. Secondary analysis and partner studies can answer to what extent its weight loss dependent or independent. I tend to like Attia for the most part but the spot in the hill hes carved out for GLP1 drug continues to be just odd"
X Link 2023-11-19T15:25Z [----] followers, [---] engagements
"Did you buy a [--] pound bird"
X Link 2023-11-22T01:57Z [----] followers, [----] engagements
"Every voter sentiment survey I see heaps criticism on the Biden admin for economic conditions but frankly it should be praise. [--]. S&P up 14% in the last year [--]. Gas down almost [--] cents in recent months [--]. Inflation approaching 3% (borderline miracle [--]. Inflation peak"
X Link 2023-11-22T19:13Z [----] followers, [---] engagements
"@AntiheroMD Oh I do love when people bury themselves. If we can agree that retention time in the intimal space correlates with oxidation level we can move on here. Tell me what biomarker is strongly correlated with ApoB particle flux into the vessel wall"
X Link 2023-11-24T02:54Z [----] followers, [--] engagements
"@AntiheroMD Trust me I know more about lipidology than you do and Ive spent more time around the nutrition/cardio social media circles than you. Ill be fine. Weve already established LDL oxidation is not necessary for intimal invasion (it literally was in the first set of responses)"
X Link 2023-11-24T03:01Z [----] followers, [--] engagements
"@AntiheroMD Oxidation of LDL contents in the intimal space is a core mechanism by which atheroma maturity takes places. Whether recirculated oxidized lipid or lipoprotein contents are a major nidus of atheroma formation is somewhat debatable but they appear to play a small role in a"
X Link 2023-11-24T03:03Z [----] followers, [--] engagements
"@AntiheroMD Concentration basis. Now lets get back to business. What serum lipid value correlates with ApoB/LDL particle flux into the intimal space"
X Link 2023-11-24T03:04Z [----] followers, [--] engagements
"@AntiheroMD Species on (proportionally very small) peripheral levels the correlations between atheroma burden and plasma levels and what tracing studies exist and you have a nice solid evidence base"
X Link 2023-11-24T03:55Z [----] followers, [--] engagements
"@AntiheroMD Tack on the immunohistological differences in vascular lesions relative to serum concentrations total proportion of circulating LDL that is oxidized in any given case and the increased proportion that occurs in individuals specifically following an MI & you have quite the case"
X Link 2023-11-24T04:25Z [----] followers, [--] engagements
"@AaronLepeska @AntiheroMD @dylanarmbruste3 I spent half of last night walking him back from retention to SFA increasing ApoB serum levels. He either will have to reject the relationship of ApoB out of whole clothe or is just unaware of the lipid content data regarding impact on ApoB levels. Neither is good"
X Link 2023-11-25T00:32Z [----] followers, [--] engagements
"The evidence that heat stress positively influences accumulation or preservation of skeletal muscle is about the same as the evidence that Im a good NBA prospect. The most important players for muscle mass: 1) Protein intake (at least 1.6g/kg body weight) 2) Resistance training 3) Omega-3s (2-4g/day triglyceride form) 4) Heat stress (from a sauna or hot tub) https://t.co/M1oOYx0rV6 The most important players for muscle mass: 1) Protein intake (at least 1.6g/kg body weight) 2) Resistance training 3) Omega-3s (2-4g/day triglyceride form) 4) Heat stress (from a sauna or hot tub)"
X Link 2023-11-25T04:57Z [----] followers, 26.9K engagements
"@DolfDoofinsky Im no apologist for carnivore but thats clearly nonsense"
X Link 2023-11-25T16:05Z [----] followers, [---] engagements
"Look for little slices of datasets and case reports that can be used for what technically counts as a publication Or would it be much much better if the same student contributed to just one or two rigorous studies that asked and evaluated important research questions"
X Link 2023-11-25T23:54Z [----] followers, [---] engagements
"That a particular field needs answered (but which take a year or more to assess) I know what my answer is. Make the tradeoff in increased workload is just too high idk. We have these brilliant med students going into fantastically competitive specialties that clearly"
X Link 2023-11-25T23:54Z [----] followers, [---] engagements
"@MedDevTX @B_Holmer Some people think Bosa is racist is an interesting way to frame the individual saying/endorsing some racist things. This is before getting into some of the other colorful parts of his personality"
X Link 2023-11-26T02:15Z [----] followers, [---] engagements
"@JTMarlin77 @MedDevTX @B_Holmer Scouting for an example of an athlete who eschews carbs and landing on that personality because you are just in search of validating a worldview doesnt strike you as at all poetic"
X Link 2023-11-26T02:35Z [----] followers, [--] engagements
"@bakrantz So you simply just dont grasp it. You are basically saying (with a dataset that is biased towards underrating the effect size) that one of the biggest demonstrated mortality benefits in medicine (1000 patient-years/95k/4.25 years) even assuming that doesnt compound and"
X Link 2023-11-27T00:11Z [----] followers, [--] engagements
"@TPenic @TalkinBaseball_ This is one of the worst copes Ive seen in a long time and I spend a non-trivial amount of time on this app which is the zenith of coping"
X Link 2023-11-27T19:46Z [----] followers, [--] engagements
"@TPenic @TalkinBaseball_ It really is only on this site that someone could so definitively argue against their own position and then try to claim some kind of intellectual victory. The unearned intellectual arrogance truly knows no bounds"
X Link 2023-11-27T20:33Z [----] followers, [--] engagements
"@TPenic @TalkinBaseball_ You literally just posted the baseball reference page confirming what i said. Im assuming this is trolling because if its not this has entered the realm of being sad"
X Link 2023-11-27T20:55Z [----] followers, [--] engagements
"College football has become such a strange game"
X Link 2023-11-28T18:15Z [----] followers, [---] engagements
"@TheBhupiThakur @paulsaladinomd @TheNutrivore @drmatthewnagra I am shocked shocked I tell you At the trials hes deemed to be the best of the bunch"
X Link 2023-11-28T21:52Z [----] followers, [---] engagements
"@JTMarlin77 You can put me in the camp that at least half of the seed oil trials have such massive flaws that its hard to interpret the aggregated data"
X Link 2023-11-29T00:40Z [----] followers, [--] engagements
"@CaloriesProper @hubermanlab Can start with the fact that they are intertwined"
X Link 2023-11-30T05:13Z [----] followers, [--] engagements
"@drscottyk I think thats a reasonable take but how would that be actionable independent of what would be done anyway"
X Link 2023-12-01T18:51Z [----] followers, [---] engagements
"Ive heard Dean Phillips talk in an extended capacity a half dozen times now. I find him eminently reasonable. Much More than most politicians Ive heard in my lifetime"
X Link 2023-12-01T19:48Z [----] followers, [---] engagements
"Changes in glucose metabolism preceding clinical symptoms has been demonstrated in various capacities for at least [--] years. Virtually anyone who was well-versed in the literature has been aware of this relationship and were able to hold neuropathology and cerebrometabolism"
X Link 2023-12-01T20:59Z [----] followers, [----] engagements
"In their head at the same time. The grant and clinical space has been dominated by the neuropathology side but its disingenuous to continue to try to bifurcate the interrelationship of the two sides or to suggest metabolism wasnt appreciated"
X Link 2023-12-01T20:59Z [----] followers, [---] engagements
"@SweetCainMusic Idk. Its a long conversation that may not be a Friday night topic"
X Link 2023-12-02T01:32Z [----] followers, [--] engagements
"Georgia and Bama both roll FSU even with Jordan Travis but you have to put FSU in otherwise why even bother with the regular season"
X Link 2023-12-03T06:40Z [----] followers, [---] engagements
"@cohensa I dont think its that cut and dry. Should it be at the discretion of the committee to discount the undefeated ACC champ with a win over LSU because their QB got hurt Thats at best a philosophical discussion where honest brokers might disagree"
X Link 2023-12-03T07:15Z [----] followers, [--] engagements
"For instance this paper does the thing that so many do they reference an athlete (LeBron in this case) as a cudgel against BMI. This is so lazy that you lose me instantly. First it is almost never reasonable to use an extreme outlier to categorize a metric broadly. Second"
X Link 2023-12-03T17:27Z [----] followers, [---] engagements
"There exists virtually no doctors or prescribers (Im sure you can find a couple of isolated nutcases) that would look at lebron and his profile and say that his BMI is concerning for adiposity. The additional case here is that AO medication cutoffs are BMI dependent"
X Link 2023-12-03T17:32Z [----] followers, [---] engagements
"@nacholeber They were doomed either way. Alabama is clearly the superior team as it stands. FSU has the resume. Their mandate is technically to choose the best teams its written into their criteria. I dont love that they can wipe away the regular season based on injury but they can"
X Link 2023-12-03T17:56Z [----] followers, [----] engagements
"@AKoutnik I think its reactionary to not having Jordan Travis and having a fairly soft schedule outside of LSU more than it is to one week of games. The argument for reacting to this week is to drop Georgia if anything"
X Link 2023-12-03T18:15Z [----] followers, [--] engagements
"If one is drinking to the point they need to be administered NAC and glutathione we need a serious caveat on the amount of alcohol or existing liver disease going on here. Also vitamin C Please 🤦♂"
X Link 2023-12-04T21:10Z [----] followers, [----] engagements
"If you conflate lean mass loss with skeletal muscle loss youre going to have a bad time"
X Link 2023-12-08T04:24Z [----] followers, [----] engagements
"Its really difficult to combat misinformation in a world where this is viewed as a strong argument. And I say this as someone who is probably more tolerant of neutral sat fat arguments than most. I want to respond to the commenter (to my dec [--] post) who posted a graph showing that cardiovascular deaths have declined since [----] in men and women. This correlation might make one think that the American Heart Association's campaign to lower cholesterol is the driving factor. https://t.co/qdQE2XL0gF I want to respond to the commenter (to my dec [--] post) who posted a graph showing that"
X Link 2023-12-10T18:20Z [----] followers, [----] engagements
"That might have been good from 70"
X Link 2023-12-11T01:58Z [----] followers, [---] engagements
"Epidemiology is trash science Look at this graph of butter consumption versus obesity rates Yall are going to have to pick one. Butter consumption has dropped 62.5% over the last [---] years while obesity and vegetable oils have soared. Must be the butter. https://t.co/3om0hfVK4i Butter consumption has dropped 62.5% over the last [---] years while obesity and vegetable oils have soared. Must be the butter. https://t.co/3om0hfVK4i"
X Link 2023-12-11T17:14Z [----] followers, [----] engagements
"Inflation is 1% away from historical target levels (which are malleable in the first place). Driver is rent which the president has minimal to modest control over in terms of driving supply. Structural problems drive these metrics to reflect a good Econ environment"
X Link 2023-12-12T18:10Z [----] followers, [---] engagements
"I dont care for Elon at all but can someone tell me why this isnt vindictive and dumb"
X Link 2023-12-13T15:01Z [----] followers, [----] engagements
"@DoctorTro It may be worth it to read the trial design before commenting in the future"
X Link 2023-12-16T15:34Z [----] followers, [---] engagements
"Now imagine people tried to argue that any of these wasnt the fundamental underwriting principle that everyone was working from"
X Link 2023-12-16T17:47Z [----] followers, [---] engagements
"@DavidB50863 Disease in these communities"
X Link 2023-12-17T19:20Z [----] followers, [--] engagements
"@DavidB50863 But lets not pretend that such an approach is a panacea. There is ample prescription of these GLP1 drug in affluent and/or economically stable populations and not just for vanity weight loss. If it was only a resources issue the use of these drugs in this population would"
X Link 2023-12-17T19:22Z [----] followers, [--] engagements
"Editors note: They replaced SGLt2s with LC and a caloric deficit. Weight loss on SGLT2s alone is pretty modest even if metabolic improvements exceed weight loss"
X Link 2023-12-19T00:37Z [----] followers, [----] engagements
"Printing money. Thats all smaller and smaller fractions is in practice. Also not for nothing but the dollar is literally the most trusted and democratized store of value in the world. Find a better specter to argue against"
X Link 2023-12-21T02:50Z [----] followers, [---] engagements
"Im not going to pretend I watch every 76ers playoff game but is part of the reason his number (and efficiency numbers) tank in the playoff is because they stop giving him a patently absurd whistle"
X Link 2023-12-21T17:04Z [----] followers, [---] engagements
"Cholesterol-containing lipoprotein infiltration of the vessel wall is literally the spearhead of the atherosclerotic cascade. Even if one was trying pitch an argument that the role of lipoproteins are over-emphasized this is essentially the selectively worst version"
X Link 2023-12-22T14:15Z [----] followers, [----] engagements
"@kunningdruger23 Its a bias towards the confluence of data. Im not in the camp that says its only ApoB as far and away the lone causal risk factor but the evidence of its sentinel role (and its validity as a therapeutic target) has been demonstrated countless times and ways"
X Link 2023-12-22T20:50Z [----] followers, [--] engagements
"Why is it always the keto/carnivore crowd that experiences the worlds most asshole-ish doctors is a seemingly selective manner"
X Link 2023-12-22T20:53Z [----] followers, [----] engagements
"@Chaddadbod Cutting out an entire food group will make it decidedly less likely and will minimize glucose spikes but total glycemic exposure is dictated by AUC exposure not transient prandial spikes. But youve consumed all the kool aid so this is fruitless"
X Link 2023-12-23T00:05Z [----] followers, [--] engagements
"Semaglutides weight loss effects extend well beyond delaying gastric emptying. Ceasing prior to surgery (and associated ileus risk) should be considered and studied"
X Link 2023-12-24T04:03Z [----] followers, [----] engagements
"Probably social media apps that feature science influencers and political zealots. If you had to pick only [--] non-negotiable (once you decide) No more ______ for me once in [----] what is that thing behavior thought etc. If you had to pick only [--] non-negotiable (once you decide) No more ______ for me once in [----] what is that thing behavior thought etc"
X Link 2023-12-26T21:18Z [----] followers, [---] engagements
"@RosenelliEM @BioLayne I will literally go through Richard Johnson claims one by one if you want. We are departing the realm of real concerns about fructose and departing for mouse megadose extrapolations"
X Link 2023-12-31T21:34Z [--] followers, [---] engagements
"I overcame playing against CeeDee lamb Flacco and Jerome Ford to win this week and its maybe the only meaningful accomplishment I had this year"
X Link 2024-01-01T00:27Z [--] followers, [---] engagements
"@CharlesMBrenner Thats like a week or more for humans. Not that its a linear comparison but it is a looooooooong time without eating for a mouse"
X Link 2024-01-04T04:30Z [--] followers, [---] engagements
"It is interesting to compare these to the reports of malaise/generalized/GI discomfort for individuals on these drugs. As in the two dont seem to line up even if they arent a direct 1:1 comparison 📣New study: semaglutide compared with non-GLP1R agonist anti-obesity medications associated with lower risk for incident (HR = 0.27) and recurrent (HR = 0.44) suicidal ideation consistent across sex age and ethnicity stratification. https://t.co/aBB3kAnKxJ H/t @ChrisPalmerMD 📣New study: semaglutide compared with non-GLP1R agonist anti-obesity medications associated with lower risk for incident (HR"
X Link 2024-01-05T19:25Z [----] followers, [---] engagements
"@MichaelMindrum Those reporting long-term mild to moderate nausea with things that used to not produce the same symptoms"
X Link 2024-01-05T20:51Z [--] followers, [--] engagements
"@Gaardsy I mean the Wolves traded [--] picks (3 unprotected) a [----] swap Kessler and others for a [--] footer in his 30s. Hed essentially have to play his contract out at this level to even reach acceptable. Indiana traded [--] of their 1st and next years (probably) OKC pick plus Bruce brown"
X Link 2024-01-17T20:53Z [----] followers, [---] engagements
"@DavidB50863 @travelingenes Im fine with improving hospital nutrition broadly but if the argument is that transient meals in hospitals are the breaking point for cancer therapy or nutritional practice I mean thats just not supported in any way"
X Link 2024-01-20T00:28Z [----] followers, [--] engagements
"@PowerTripBets Im certainly am in favor of gearing up to to get a QB. But getting to [--] or [--] is going to take the whole farm and Jayden Daniels is a high risk guy. I think one of Nix Penix McCarthy Travis etc will be good but its a roll of the dice and I dont think any are transcendent"
X Link 2024-01-22T02:59Z [----] followers, [---] engagements
"1. Less frequent eating doesnt increase ldl per se. Long-term fasting does but thats a unique case. [--]. Weight loss on overweight or obese individuals routinely decreases ldl in the intermediate to long term. This requires hyper fixation on lean individuals 🤔Eating less frequently RAISES LDL ☠Snacking more DECREASES LDL 🤔Lowering carbs RAISES LDL ☠Processed carbs DECREASES LDL 🤔Low BMI RAISES LDL ☠High BMI DECREASES LDL Focusing on LDL while disregarding obesity & metabolic syndrome is MALPRACTICE 🤔Eating less frequently RAISES LDL ☠Snacking more DECREASES LDL 🤔Lowering carbs RAISES LDL"
X Link 2024-01-26T18:59Z [----] followers, [---] engagements
"@JonKrawczynski True but its time to go. They have reasonably [--] months to correct what are now a lot of non-trivial concerns on offense and in the playoffs teams will space them out such that it will be harder to have the same defensive advantage"
X Link 2024-01-28T22:52Z [----] followers, [---] engagements
"@JonKrawczynski I would agree if not for the fact that the problems that absolutely plagued them last year (including early year with KAT) werent showing back up. Turnovers are A1 and maybe can be fixed but they also have become reliant on isolation possessions especially in the late game"
X Link 2024-01-28T23:11Z [----] followers, [--] engagements
"@JonKrawczynski Where they arent very efficient unless Ant is having one of his superhero nights. They struggle with teams that can out [--] shooter in the floor which are OKC Den LAC Pho etc. Conley keeps them settled when hes out there but he cant play [--] minutes/game"
X Link 2024-01-28T23:12Z [----] followers, [--] engagements
"This game is a full-fledged treatise on how probability is taught in the American educational system and how Americans do (or more accurately do not) understand variance"
X Link 2024-01-29T02:39Z [----] followers, [---] engagements
"@BHBEnjoyer Among others"
X Link 2024-01-31T15:41Z [----] followers, [--] engagements
"@BHBEnjoyer Prior to [----] Idk id have to look. Im hardly a fan of convenient timeframes and not sure why it matters"
X Link 2024-01-31T15:42Z [----] followers, [--] engagements
"I could unpack this [--] ways to Sunday but Ill leave it at this: In sports it is quite rare to see an outstanding player (elite professional) become a best in class coach. It is much more common to see guys who barely spent time on a roster or came up through the film room. I think its fair to ask if the MD or scientist or public health official saying to do X or not do Y looks and sounds healthy and vital. I avoid going to a dentist with bad teeth. What do you think I sense diverging opinions on this. I think its fair to ask if the MD or scientist or public health official saying to do X or"
X Link 2024-01-31T23:01Z [----] followers, [----] engagements
"@GeorgiaEdeMD So they are making a common mistake here assuming their 60-70% claim is accurate (it would be essentially the highest suggested by any group and should be validated and published) LBM cannot be equated to muscle mass directly. There are a number of sources of lean mass"
X Link 2024-02-04T18:01Z [----] followers, [---] engagements
"@GeorgiaEdeMD Including organ weights which would be expected to decline with corresponding weight loss. Further data on loss of muscle strength has been much more modest even in the presence of (not half) confirmed muscle loss"
X Link 2024-02-04T18:03Z [----] followers, [--] engagements
"@GeorgiaEdeMD Further still the side effects noted are overwhelmingly nausea and GI side effects that lessen over time. And while they may try to suggest that 70% come off them within a year thats largely due time accessibility and affordability"
X Link 2024-02-04T18:05Z [----] followers, [--] engagements
"@GeorgiaEdeMD Moreover if they are accurate in that they were treating patients with Ozempic for glycemia management they werent even utilizing it for a weight loss indication. If they were they were utilizing it off label or just substituting Ozempic for WeGovy. This is before"
X Link 2024-02-04T18:07Z [----] followers, [--] engagements
"@GeorgiaEdeMD We would even talk about them using tirzepatide which appears to result in less lean mass loss overall (relevance tbd)"
X Link 2024-02-04T18:08Z [----] followers, [--] engagements
"@GeorgiaEdeMD As for there ability to sustain GLP1-induced weight loss its not uncommon for weight loss to be sustained for a year with intensive clinical intervention (theyve published their own data that presumably reinforces this concept)but they also show regression past this timepoint"
X Link 2024-02-04T18:12Z [----] followers, [--] engagements
"@GeorgiaEdeMD So Im not really sure what relevance theyre claiming this has outside of trying to denigrate the drugs. There are real problems with the utilization of these drugs. The need to hand wave false flag concerns is totally unnecessary and makes one wonder about motivations"
X Link 2024-02-04T18:14Z [----] followers, [--] engagements
"Its hard to exaggerate how bad this logic is. Treatments with high efficacy have no obligation to be the core driver of the development of the pathology. See melanoma and checkpoint inhibitors as perhaps the best example. There arent enough facepalm emojis for this rationale Obesity is not an Ozempic deficiency. Heart disease is not a statin deficiency. Diabetes is not a metformin deficiency. Depression is not an SSRI deficiency. ADHD is not an Adderall deficiency. Were being lied to. Obesity is not an Ozempic deficiency. Heart disease is not a statin deficiency. Diabetes is not a metformin"
X Link 2024-02-07T06:03Z [----] followers, [----] engagements
"Dictators and authoritarians across the hemispheric north love Tucker Carlson and the American right needs their forum from which to lap it up. @elonmusk please confirm I hope X has enough server capacity for when this interview drops. @elonmusk please confirm I hope X has enough server capacity for when this interview drops. @elonmusk please confirm"
X Link 2024-02-07T06:17Z [----] followers, [---] engagements
"@Justinredalen @elonmusk [--] million is n cable news is massive. His videos on Twitter get millions to tens of millions of views. He gets lots of YouTube traction beyond this. But okay"
X Link 2024-02-07T06:32Z [----] followers, [--] engagements
"@fellowshipnate @hammerotass Safety record is extremely good. Weve covered recidivism muscle loss (exaggerated as it is) can be mitigated. Look I get you are incentivized to be against these drugs on multiple levels but stick to empirically supported arguments against them at minimum"
X Link 2024-02-07T22:27Z [----] followers, [--] engagements
"@fellowshipnate @hammerotass @pfizer Also you have but to simply google why the [--] years of cover (it actually wasnt [--] but you do you) as a prevention from getting sued is a comically dumb argument but weve already demonstrated that youre unwilling to google to help your case so 🤷♂"
X Link 2024-02-08T17:06Z [----] followers, [--] engagements
"@fellowshipnate @hammerotass @pfizer I will again ask you to pick a specific point in which you would like to defend empirically. You can pick literally any of them. Weve established that you have a strong fear of any level of institutional authority such that you dont even trust randomized controlled trials"
X Link 2024-02-09T18:13Z [----] followers, [--] engagements
"Do people that are calling Tucker an American hero (real thing not an exaggeration) want to go ahead and mention that he was literally hand-picked by the Kremlin for his pro-Russian and authoritarian-tolerant positions"
X Link 2024-02-09T19:10Z [----] followers, [---] engagements
"@Mark_C_Casper We could go through his commentary and leave it open to individual interpretation but the Kremlin phrased it has having ideas that differed from the main contingent of American journalistic outlets. Which one can interpret however you want coming from the Kremlin"
X Link 2024-02-09T19:54Z [----] followers, [--] engagements
"@Mark_C_Casper Nope I very clearly laid out the context here. Spin to your leisure I didnt leave much ambiguity"
X Link 2024-02-09T21:48Z [----] followers, [--] engagements
"@Mark_C_Casper And I very clearly delineated that this was not based on being a mouthpiece for the administration. Its based on pro-Russia rhetoric over and over and over again. Its really not tough"
X Link 2024-02-09T21:52Z [----] followers, [--] engagements
"@Mark_C_Casper I defined pro-Russia as be pro-Russia because the implication is self evident. This isnt complicated nor was it intended to be"
X Link 2024-02-09T23:59Z [----] followers, [--] engagements
"@AndrewYang He lost to Marianne Williamson dude. You cant claim to be existentially concerned about electability and be touting Mr. Phillips (and I say this as someone who thinks Phillips is fairly compelling on the whole)"
X Link 2024-02-10T20:02Z [----] followers, [---] engagements
"Editors note: its an assault weapons ban. That noted communist Bill Clinton passed one nationally in [----] The radical Communist Democrats of Minnesota just introduced a bill to ban certain types of rifles and institute a buyback program. This is what happens when you elect crazy activists to office and have complete rule over an entire state government. https://t.co/uzAXU7FP0m The radical Communist Democrats of Minnesota just introduced a bill to ban certain types of rifles and institute a buyback program. This is what happens when you elect crazy activists to office and have complete rule"
X Link 2024-02-11T14:11Z [----] followers, [---] engagements
"@MichaelAlbertMD I mean thats fairly hard to argue definitely from their data. The period of reduced food intake was longer than the window in which there was active weight loss of a demonstrably lower weight gain trajectory in either sex"
X Link 2024-02-11T20:01Z [----] followers, [--] engagements
"Introducing Rogans core audience These white kids havent been indoctrinated in the least. Nope. https://t.co/Lls8Jyzzeg These white kids havent been indoctrinated in the least. Nope. https://t.co/Lls8Jyzzeg"
X Link 2024-02-12T04:16Z [----] followers, [----] engagements
"@elonmusk Im sure youre ready to endorse a modern tax structure that would tax you more to raise revenues to pay the interest/pay it down"
X Link 2024-02-12T23:49Z [----] followers, [--] engagements
"@RPLongSW @elonmusk So this is actually a longer conversation. It is generally considered to decrease private investment (although that data is much noisier than older Econ would say). It can and has spurred public investment throughout the 1900s"
X Link 2024-02-13T00:19Z [----] followers, [--] engagements
"@RPLongSW @elonmusk This is empirically false. I can pull the data when I get home"
X Link 2024-02-13T00:32Z [----] followers, [--] engagements
"Here is the ingredient list for McDonalds pickles. 7/10 are ingredients for pickled cucumbers. [--] are preservatives that are well studied and safe in humans. The last is color. But cool story bro. This is CRAZY 😳 @McDonalds pickles contain [--] ingredients Over 60% of our calories come from processed foods today and I believe they are the biggest driver of chronic diseases. Ditch the processed foods and eat REAL foods https://t.co/MMe8nzAHpo This is CRAZY 😳 @McDonalds pickles contain [--] ingredients Over 60% of our calories come from processed foods today and I believe they are the biggest"
X Link 2024-02-13T02:50Z [----] followers, [----] engagements
"@RobertKennedyJr I honestly cannot comprehend how any rationale actor would assess support for Ukraine and Taiwan specifically as anything short of morally correct not to mention outstanding foreign policy from just a net investment perspective"
X Link 2024-02-13T05:26Z [----] followers, [---] engagements
"1. They have (arguably rightly) declared martial law which prohibit elections. Also Ukrainians dont want to have elections based on polling. [--]. This really papers of the Lira story as a political murder. Probably google the details on that. Tuckers definitely not pro-Russia BREAKING: Tucker Carlson says Ukraine shouldn't receive any more funds after canceling their elections and kiIIing an American journalist. Do you agree https://t.co/W5J2i8e7Tu BREAKING: Tucker Carlson says Ukraine shouldn't receive any more funds after canceling their elections and kiIIing an American journalist. Do you"
X Link 2024-02-13T05:58Z [----] followers, [---] engagements
"@Mark_C_Casper They pushed off a full-scale takeover of at minimum the Donbas region. Russian military has regrouped after suffering major setbacks in the first phase of the war and has a larger fighting force but they are still primarily fighting as in invasion force"
X Link 2024-02-13T06:52Z [----] followers, [--] engagements
"@MichaelMindrum @AKoutnik @BenBikmanPhD True but I am rather specifically noting in this case that ingestion and infusion of lipid causes a transient insulin resistance namely at the level of skeletal muscle. This may be evolutionarily tied to meal partitioning or fasting mobilization hard to say"
X Link 2024-02-16T04:56Z [----] followers, [---] engagements
"@AKoutnik @UKLowCarb @BenBikmanPhD @Gonzalez_JT Dont think I am arguing this. Im very specifically arguing that there is a transient increase in muscle insulin resistance that may be somewhat sustained under chronically elevated FFA conditions. If there isnt any glucose intake or GSIS it may not matter much"
X Link 2024-02-16T20:26Z [----] followers, [--] engagements
"@sdskol1983 Can you point to a professional sports franchise who has opened their books outside of the Packers reporting limited financial information required due to public ownership"
X Link 2024-02-21T20:29Z [----] followers, [--] engagements
"Antivaxers: the CDC was wrong about everything. CDC issues new guidance saying its fine to do stuff while still infectious. Antivaxers: see we were right the whole time If you got vaccinated just admit you got scammed If you got vaccinated just admit you got scammed"
X Link 2024-03-03T05:18Z [----] followers, [---] engagements
"@WallStreetSilv How do Twitters ad revenue since Elon bought it"
X Link 2024-03-04T10:54Z [----] followers, [--] engagements
"Stop trying to make strain-specific boosters into something scary. Weve been doing it for the flu for decades. CDC now says they can stay one step ahead of a virus that's always changing. So now they can predict new mutations and when it will occur This is lunacy #vaccinesafety CDC now says they can stay one step ahead of a virus that's always changing. So now they can predict new mutations and when it will occur This is lunacy #vaccinesafety"
X Link 2024-03-07T03:36Z [----] followers, [---] engagements
"@RobertKennedyJc Damn I fell for the parody account. Im better than this"
X Link 2024-03-07T03:38Z [----] followers, [--] engagements
"@Justinredalen @ClayTravis I already stated that it is of no import if you want to compared red to red blue to blue or a mix. Id make the exact same argument regarding. The impacts are only so exaggerated in such a hyper-partisan decelerationist legislative body"
X Link 2024-03-07T21:32Z [----] followers, [--] engagements
"@Justinredalen @ClayTravis It objectively doesnt. Its a broad hand wave to eschew actual scholarship in reporting rates for undocumented individuals which universally points to them being undercounted (for obvious and non-obvious reasons)"
X Link 2024-03-09T03:54Z [----] followers, [--] engagements
"@Justinredalen @ClayTravis This same story happens for citizens at a far higher frequency according to every crime analysis This is devolving into a bad Fox News segment. Please do better or stop wasting time"
X Link 2024-03-09T05:16Z [----] followers, [--] engagements
"@TomCottonAR @KatieBrittforAL They are attacking her because her chosen stock example was an event that occurred in Mexico during the Bush [--] administration. That alongside her Laken Riley response which clearly was changed last minute as she didnt expect Biden to mention her. Its okay to admit it was bad"
X Link 2024-03-10T10:16Z [----] followers, [--] engagements
"Pay the toll this year draft your rookie QB (Drake Maye) come back with tons of ammo this time next year. #Vikings are now the league leader in dead money at $57.3M. Packers at number [--] at $46.5M. Seahawks are 3rd at $36M #Vikings are now the league leader in dead money at $57.3M. Packers at number [--] at $46.5M. Seahawks are 3rd at $36M"
X Link 2024-03-13T00:24Z [----] followers, [---] engagements
"Lots of commentary that the Vikings are going to move to 4-8 and draft McCarthy and the cost of [--] firsts and a kicker. QBs should be considered on their own merits but here are the 4th QBs taken in recent years: 2023: Will Levis 2022: Matt Corral 2021: Justin Fields"
X Link 2024-03-16T04:22Z [----] followers, [---] engagements
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