[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @Optimistic24228 OptimisticRaidersFan OptimisticRaidersFan posts on X about $gpcr, $sdgr, $lly, $mplt the most. They currently have XXX followers and XXX posts still getting attention that total XXXXX engagements in the last XX hours. ### Engagements: XXXXX [#](/creator/twitter::1941951471227928576/interactions)  - X Week XXXXX -X% - X Month XXXXXX +222% ### Mentions: XX [#](/creator/twitter::1941951471227928576/posts_active)  - X Week X -XX% - X Month XXX -XXXX% ### Followers: XXX [#](/creator/twitter::1941951471227928576/followers)  - X Week XXX +9.30% - X Month XXX +28% ### CreatorRank: XXXXXXXXX [#](/creator/twitter::1941951471227928576/influencer_rank)  ### Social Influence **Social category influence** [stocks](/list/stocks) [finance](/list/finance) [currencies](/list/currencies) [cryptocurrencies](/list/cryptocurrencies) **Social topic influence** [$gpcr](/topic/$gpcr) #14, [$sdgr](/topic/$sdgr) #9, [$lly](/topic/$lly) #149, [$mplt](/topic/$mplt), [$vktx](/topic/$vktx), [$glxy](/topic/$glxy) #30, [built](/topic/built), [$zeal](/topic/$zeal), [$mtsr](/topic/$mtsr), [hmm](/topic/hmm) **Top accounts mentioned or mentioned by** [@usermaynotexist](/creator/undefined) [@biotech2k1](/creator/undefined) [@researchpulse1](/creator/undefined) [@theshadowofbong](/creator/undefined) [@gilamonstrum](/creator/undefined) [@empiricalcontra](/creator/undefined) [@pushastee](/creator/undefined) [@bidetmarxman](/creator/undefined) [@lutherml](/creator/undefined) [@rhouseresearch](/creator/undefined) [@fiorellaisabelm](/creator/undefined) [@karmotrinedrea1](/creator/undefined) [@marx2thamax](/creator/undefined) [@damnjehu](/creator/undefined) [@primarycatdad](/creator/undefined) [@gg4348745710447](/creator/undefined) [@faytuksnetwork](/creator/undefined) [@grok](/creator/undefined) [@scientistmike35](/creator/undefined) [@deemthedreem](/creator/undefined) **Top assets mentioned** [Schrodinger, Inc. Common Stock (SDGR)](/topic/$sdgr) [Eli Lilly and Company (LLY)](/topic/$lly) [Viking Therapeutics, Inc (VKTX)](/topic/$vktx) [Galaxy Digital Inc. (GLXY)](/topic/$glxy) [Metsera, Inc. Common Stock (MTSR)](/topic/$mtsr) [AstraZeneca PLC (AZN)](/topic/$azn) [Recursion Pharmaceuticals, Inc. Class A Common Stock (RXRX)](/topic/$rxrx) [Bitcoin (BTC)](/topic/bitcoin) [AltLayer (ALT)](/topic/$alt) ### Top Social Posts Top posts by engagements in the last XX hours "Out of all of them tho $SDGR has built the platform that has actually delivered molecules to its partners in clinical trials" [X Link](https://x.com/Optimistic24228/status/1992320140088860736) 2025-11-22T19:51Z XXX followers, XXX engagements "Nvm forgot Cobenfy failed for Alzheimer's as well lol no Bueno on $MPLT upside for me" [X Link](https://x.com/Optimistic24228/status/1993068935105905058) 2025-11-24T21:27Z XXX followers, XXX engagements "Waiting on to enter $MPLT as it gets closer to XX. The schizophrenia indications still hold real value. Will enter next month if the $GPCR swing goes well" [X Link](https://x.com/Optimistic24228/status/1993756863528386972) 2025-11-26T19:00Z XXX followers, XXX engagements "Both $GPCR and $VKTX have lead assets that are essentially "me toos" of Lily's top assets with worse tolerability profiles. It should become obvious over time why $ZEAL and $MTSR were valued highly over them. To me $MTSR was the clear best given dosing COGS/API and tolerability" [X Link](https://x.com/Optimistic24228/status/1993812227254899104) 2025-11-26T22:40Z XXX followers, XXX engagements "Making biological causal claims and the study didn't actually control for biomarker variance nor physiological and environmental factors is a study you shouldn't take seriously other than "this might be useful if they refined it much more for accuracy" and thats it" [X Link](https://x.com/Optimistic24228/status/1995523999233872091) 2025-12-01T16:02Z XXX followers, XXX engagements "In an era where GLP1s also have so much broad positive effects and are having an uptake in use in the population controlling for GLP1 use will also become critical. A hormone (or multiple) can help neuro function but so does reducing inflammation & high blood sugar & being fit" [X Link](https://x.com/Optimistic24228/status/1995524979950301505) 2025-12-01T16:06Z XXX followers, XXX engagements "On second thought. Double bottom on the weekly for $GPCR. Hmm" [X Link](https://x.com/Optimistic24228/status/1997007180055347455) 2025-12-05T18:16Z XXX followers, XXX engagements "Another underlooked negative aspect for $GPCR is $AZN also reporting their 2b data Orforglipron clone they got from Eccogene. The Astrazeneca small molecule has much better PK/PD than Aleniglipron" [X Link](https://x.com/Optimistic24228/status/1997390232518291928) 2025-12-06T19:38Z XXX followers, XXX engagements "Also include the morphic asset that $LLY is advancing" [X Link](https://x.com/Optimistic24228/status/1997806209857208743) 2025-12-07T23:11Z XXX followers, XXX engagements "Make or break moment for $RXRX Monday. Lead asset. If its Best in class for the rare disease indication the pipeline gets validation" [X Link](https://x.com/Optimistic24228/status/1997010172552884544) 2025-12-05T18:28Z XXX followers, XXX engagements "Went all cash again till Fed decision" [X Link](https://x.com/Optimistic24228/status/1998049143399596160) 2025-12-08T15:16Z XXX followers, XXX engagements "@JCanNuSH @RichardPociask @PharmDabbler The tolerability was fine really. It was the COGs that was the issue. Anything less than stellar with high COGS is not justifiable. Having competitive data but with way worse COGS is a no go thats why they sold off. Placebo adjusted discontinuation wasn't the issue" [X Link](https://x.com/Optimistic24228/status/1998089550418313259) 2025-12-08T17:57Z XXX followers, XX engagements "@GilaMonstrum Indeed which is why they will be raising cash immediately from this pump lol. I believe it started in August on the 15th and it's a similar XX week trial. I think enrollment finished in October so looking at next August for data there. Imo their best asset is Amylin" [X Link](https://x.com/Optimistic24228/status/1998142625015362027) 2025-12-08T21:28Z XXX followers, XXX engagements "@Luther__ML It doesnt matter if they read it or not lol its not like they'd do anything with the information atp. Plus what Lenin wrote at this time is elementary (but fundamental and foundational) to whats happening now. These folks just idealists they need a reality check first" [X Link](https://x.com/Optimistic24228/status/1998166583945093504) 2025-12-08T23:03Z XXX followers, XX engagements "@rand_Kei @jacobin Renewable energy can't power heavy industry since they are ineffective at generating thermal energy. Get a clue" [X Link](https://x.com/Optimistic24228/status/1998558703029813318) 2025-12-10T01:01Z XXX followers, XX engagements "If there is any of the Techbios that can make money off their software its definitely $SDGR. They already make high margin revenues and have partnered molecules advancing like the DACRA for $GPCR (which imo will be their best asset definitely should aleniglipron disappoint)" [X Link](https://x.com/Optimistic24228/status/1997805685044830564) 2025-12-07T23:09Z XXX followers, XXX engagements "Also TAK-279 which is in phase X for Takeda in psoriasis. $SDGR has delivered molecules that BP covets" [X Link](https://x.com/Optimistic24228/status/1997807012286238876) 2025-12-07T23:14Z XXX followers, XXX engagements "Amylin data clearly shows they don't need titration. The highest untitrated Amylin dose runs laps on GLP1 tolerability. Max weight loss with lowest side effects will come from Amylin. Amylin will dominate cosmetic weight loss market. GLP/GIP/Glucagon for better health outcomes" [X Link](https://x.com/Optimistic24228/status/1997839042680127900) 2025-12-08T01:22Z XXX followers, XXX engagements "I don't see $GPCR going above XXX mg for Aleniglipron btw. That liver data already risky at XXX mg. No way they do XXX or XXX. Going to cap it at XXX like $LLy capped orforglipron at XX mg and not XX mg" [X Link](https://x.com/Optimistic24228/status/1998088976083939450) 2025-12-08T17:55Z XXX followers, XXX engagements "@Biotech2k1 Definitely add an energy portfolio if you haven't already" [X Link](https://x.com/Optimistic24228/status/1998130912941559933) 2025-12-08T20:41Z XXX followers, XX engagements "@GilaMonstrum I believe AZD5004 likely comes out before years end. I bet it performs better. Also $LLY dropped the patent for their small molecule Amylin with superior receptor affinity of X nm for both Calcitonin and Amylin. The main advantage for structure is first in class atp for amylin" [X Link](https://x.com/Optimistic24228/status/1998165648246190189) 2025-12-08T22:59Z XXX followers, XX engagements "$glxy running on that bitcoin swing" [X Link](https://x.com/Optimistic24228/status/1998442372150235509) 2025-12-09T17:19Z XXX followers, XXX engagements "Thats why stanning in general aside from being embarrassing is utterly pathetic and without dignity. Worshipping someone to the point of emotional instability who would look at you in disgust generally due to class status and earning power" [X Link](https://x.com/Optimistic24228/status/1998447211194319135) 2025-12-09T17:38Z XXX followers, XXX engagements "Like conversations among the elite from entertainment to tech spaces to finance shows a common theme. Pure disdain by many for the average man. As long as they control means of production you are going to get things like what you see currently in the US" [X Link](https://x.com/Optimistic24228/status/1998447708403896518) 2025-12-09T17:40Z XXX followers, XXX engagements "Some Chinese assets in Obesity that have best in class data early on for peptides and small molecules or true differentiation in half-life for dosing. Price wars are now a given in the space also and Reta is otw. The longer any company waits to sell the worse the BO price" [X Link](https://x.com/Optimistic24228/status/1998457455508889946) 2025-12-09T18:19Z XXX followers, XXX engagements "This is something to consider for $VKTX $ALT $GPCR. Also after trying to find more good ROI plays I tend to agree with @Biotech2k1 most of the good late stage plays overvalued. Its a chase now for binary pops. Market looks toppy but there is a rate cut & QE so we will see" [X Link](https://x.com/Optimistic24228/status/1998458418034618551) 2025-12-09T18:23Z XXX followers, XXX engagements "@DeemTheDreem Rate of profit is falling so they trying to merge companies to destroy excess capital and deflation pressures and using all types of accounting and financial measures to boost growth. They so scared of deflation they conceding to stagflation to keep equities growing" [X Link](https://x.com/Optimistic24228/status/1998461687876247969) 2025-12-09T18:36Z XXX followers, XXX engagements "@DeemTheDreem Will only get worse once the bubble officially pops. Milennials better start getting used to saying goodbye to many nostalgic companies" [X Link](https://x.com/Optimistic24228/status/1998462256968069364) 2025-12-09T18:38Z XXX followers, XXX engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@Optimistic24228 OptimisticRaidersFanOptimisticRaidersFan posts on X about $gpcr, $sdgr, $lly, $mplt the most. They currently have XXX followers and XXX posts still getting attention that total XXXXX engagements in the last XX hours.
Social category influence stocks finance currencies cryptocurrencies
Social topic influence $gpcr #14, $sdgr #9, $lly #149, $mplt, $vktx, $glxy #30, built, $zeal, $mtsr, hmm
Top accounts mentioned or mentioned by @usermaynotexist @biotech2k1 @researchpulse1 @theshadowofbong @gilamonstrum @empiricalcontra @pushastee @bidetmarxman @lutherml @rhouseresearch @fiorellaisabelm @karmotrinedrea1 @marx2thamax @damnjehu @primarycatdad @gg4348745710447 @faytuksnetwork @grok @scientistmike35 @deemthedreem
Top assets mentioned Schrodinger, Inc. Common Stock (SDGR) Eli Lilly and Company (LLY) Viking Therapeutics, Inc (VKTX) Galaxy Digital Inc. (GLXY) Metsera, Inc. Common Stock (MTSR) AstraZeneca PLC (AZN) Recursion Pharmaceuticals, Inc. Class A Common Stock (RXRX) Bitcoin (BTC) AltLayer (ALT)
Top posts by engagements in the last XX hours
"Out of all of them tho $SDGR has built the platform that has actually delivered molecules to its partners in clinical trials"
X Link 2025-11-22T19:51Z XXX followers, XXX engagements
"Nvm forgot Cobenfy failed for Alzheimer's as well lol no Bueno on $MPLT upside for me"
X Link 2025-11-24T21:27Z XXX followers, XXX engagements
"Waiting on to enter $MPLT as it gets closer to XX. The schizophrenia indications still hold real value. Will enter next month if the $GPCR swing goes well"
X Link 2025-11-26T19:00Z XXX followers, XXX engagements
"Both $GPCR and $VKTX have lead assets that are essentially "me toos" of Lily's top assets with worse tolerability profiles. It should become obvious over time why $ZEAL and $MTSR were valued highly over them. To me $MTSR was the clear best given dosing COGS/API and tolerability"
X Link 2025-11-26T22:40Z XXX followers, XXX engagements
"Making biological causal claims and the study didn't actually control for biomarker variance nor physiological and environmental factors is a study you shouldn't take seriously other than "this might be useful if they refined it much more for accuracy" and thats it"
X Link 2025-12-01T16:02Z XXX followers, XXX engagements
"In an era where GLP1s also have so much broad positive effects and are having an uptake in use in the population controlling for GLP1 use will also become critical. A hormone (or multiple) can help neuro function but so does reducing inflammation & high blood sugar & being fit"
X Link 2025-12-01T16:06Z XXX followers, XXX engagements
"On second thought. Double bottom on the weekly for $GPCR. Hmm"
X Link 2025-12-05T18:16Z XXX followers, XXX engagements
"Another underlooked negative aspect for $GPCR is $AZN also reporting their 2b data Orforglipron clone they got from Eccogene. The Astrazeneca small molecule has much better PK/PD than Aleniglipron"
X Link 2025-12-06T19:38Z XXX followers, XXX engagements
"Also include the morphic asset that $LLY is advancing"
X Link 2025-12-07T23:11Z XXX followers, XXX engagements
"Make or break moment for $RXRX Monday. Lead asset. If its Best in class for the rare disease indication the pipeline gets validation"
X Link 2025-12-05T18:28Z XXX followers, XXX engagements
"Went all cash again till Fed decision"
X Link 2025-12-08T15:16Z XXX followers, XXX engagements
"@JCanNuSH @RichardPociask @PharmDabbler The tolerability was fine really. It was the COGs that was the issue. Anything less than stellar with high COGS is not justifiable. Having competitive data but with way worse COGS is a no go thats why they sold off. Placebo adjusted discontinuation wasn't the issue"
X Link 2025-12-08T17:57Z XXX followers, XX engagements
"@GilaMonstrum Indeed which is why they will be raising cash immediately from this pump lol. I believe it started in August on the 15th and it's a similar XX week trial. I think enrollment finished in October so looking at next August for data there. Imo their best asset is Amylin"
X Link 2025-12-08T21:28Z XXX followers, XXX engagements
"@Luther__ML It doesnt matter if they read it or not lol its not like they'd do anything with the information atp. Plus what Lenin wrote at this time is elementary (but fundamental and foundational) to whats happening now. These folks just idealists they need a reality check first"
X Link 2025-12-08T23:03Z XXX followers, XX engagements
"@rand_Kei @jacobin Renewable energy can't power heavy industry since they are ineffective at generating thermal energy. Get a clue"
X Link 2025-12-10T01:01Z XXX followers, XX engagements
"If there is any of the Techbios that can make money off their software its definitely $SDGR. They already make high margin revenues and have partnered molecules advancing like the DACRA for $GPCR (which imo will be their best asset definitely should aleniglipron disappoint)"
X Link 2025-12-07T23:09Z XXX followers, XXX engagements
"Also TAK-279 which is in phase X for Takeda in psoriasis. $SDGR has delivered molecules that BP covets"
X Link 2025-12-07T23:14Z XXX followers, XXX engagements
"Amylin data clearly shows they don't need titration. The highest untitrated Amylin dose runs laps on GLP1 tolerability. Max weight loss with lowest side effects will come from Amylin. Amylin will dominate cosmetic weight loss market. GLP/GIP/Glucagon for better health outcomes"
X Link 2025-12-08T01:22Z XXX followers, XXX engagements
"I don't see $GPCR going above XXX mg for Aleniglipron btw. That liver data already risky at XXX mg. No way they do XXX or XXX. Going to cap it at XXX like $LLy capped orforglipron at XX mg and not XX mg"
X Link 2025-12-08T17:55Z XXX followers, XXX engagements
"@Biotech2k1 Definitely add an energy portfolio if you haven't already"
X Link 2025-12-08T20:41Z XXX followers, XX engagements
"@GilaMonstrum I believe AZD5004 likely comes out before years end. I bet it performs better. Also $LLY dropped the patent for their small molecule Amylin with superior receptor affinity of X nm for both Calcitonin and Amylin. The main advantage for structure is first in class atp for amylin"
X Link 2025-12-08T22:59Z XXX followers, XX engagements
"$glxy running on that bitcoin swing"
X Link 2025-12-09T17:19Z XXX followers, XXX engagements
"Thats why stanning in general aside from being embarrassing is utterly pathetic and without dignity. Worshipping someone to the point of emotional instability who would look at you in disgust generally due to class status and earning power"
X Link 2025-12-09T17:38Z XXX followers, XXX engagements
"Like conversations among the elite from entertainment to tech spaces to finance shows a common theme. Pure disdain by many for the average man. As long as they control means of production you are going to get things like what you see currently in the US"
X Link 2025-12-09T17:40Z XXX followers, XXX engagements
"Some Chinese assets in Obesity that have best in class data early on for peptides and small molecules or true differentiation in half-life for dosing. Price wars are now a given in the space also and Reta is otw. The longer any company waits to sell the worse the BO price"
X Link 2025-12-09T18:19Z XXX followers, XXX engagements
"This is something to consider for $VKTX $ALT $GPCR. Also after trying to find more good ROI plays I tend to agree with @Biotech2k1 most of the good late stage plays overvalued. Its a chase now for binary pops. Market looks toppy but there is a rate cut & QE so we will see"
X Link 2025-12-09T18:23Z XXX followers, XXX engagements
"@DeemTheDreem Rate of profit is falling so they trying to merge companies to destroy excess capital and deflation pressures and using all types of accounting and financial measures to boost growth. They so scared of deflation they conceding to stagflation to keep equities growing"
X Link 2025-12-09T18:36Z XXX followers, XXX engagements
"@DeemTheDreem Will only get worse once the bubble officially pops. Milennials better start getting used to saying goodbye to many nostalgic companies"
X Link 2025-12-09T18:38Z XXX followers, XXX engagements
/creator/twitter::Optimistic24228