# ![@NatureCellBio Avatar](https://lunarcrush.com/gi/w:26/cr:twitter::111305843.png) @NatureCellBio Nature Cell Biology

Nature Cell Biology posts on X about article, study, role for, route the most. They currently have [-------] followers and [---] posts still getting attention that total [-----] engagements in the last [--] hours.

### Engagements: [-----] [#](/creator/twitter::111305843/interactions)
![Engagements Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::111305843/c:line/m:interactions.svg)

- [--] Week [-----] -73%
- [--] Month [-------] +614%
- [--] Months [-------] +2,345%
- [--] Year [---------] +31%

### Mentions: [--] [#](/creator/twitter::111305843/posts_active)
![Mentions Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::111305843/c:line/m:posts_active.svg)

- [--] Week [--] +33%
- [--] Month [--] +13%
- [--] Months [--] +340%
- [--] Year [--] -30%

### Followers: [-------] [#](/creator/twitter::111305843/followers)
![Followers Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::111305843/c:line/m:followers.svg)

- [--] Month [-------] -0.16%
- [--] Months [-------] -1.40%
- [--] Year [-------] -1.40%

### CreatorRank: undefined [#](/creator/twitter::111305843/influencer_rank)
![CreatorRank Line Chart](https://lunarcrush.com/gi/w:600/cr:twitter::111305843/c:line/m:influencer_rank.svg)

### Social Influence

**Social category influence**
[finance](/list/finance)  2.54% [technology brands](/list/technology-brands)  1.69% [ncaa basketball](/list/ncaa-basketball)  1.69% [currencies](/list/currencies)  0.85% [travel destinations](/list/travel-destinations)  0.85%

**Social topic influence**
[article](/topic/article) #204, [study](/topic/study) 3.39%, [role for](/topic/role-for) 2.54%, [route](/topic/route) 1.69%, [in the](/topic/in-the) 1.69%, [acquisition](/topic/acquisition) 1.69%, [accumulation](/topic/accumulation) 1.69%, [step](/topic/step) 0.85%, [major](/topic/major) 0.85%, [key](/topic/key) 0.85%

**Top accounts mentioned or mentioned by**
[@demetriadeslab](/creator/undefined) [@cuilabchem](/creator/undefined) [@stanforduchem](/creator/undefined) [@stanfordchemh](/creator/undefined) [@bianxiaoc](/creator/undefined) [@eddagschulz](/creator/undefined) [@filipovskalab](/creator/undefined) [@kraftlabfr](/creator/undefined) [@wilflinglab](/creator/undefined) [@sloanlab](/creator/undefined) [@caitlinsojka](/creator/undefined) [@jingtaoguo](/creator/undefined) [@leqianyu](/creator/undefined) [@szmydradoslaw](/creator/undefined) [@thecesarelab](/creator/undefined) [@radoncdocgee](/creator/undefined) [@scientistjoanna](/creator/undefined) [@ruggerodavide](/creator/undefined) [@natcellbionaturecom](/creator/undefined) [@karalmckinley](/creator/undefined)

**Top assets mentioned**
[Enzyme (MLN)](/topic/enzyme) [Flux (FLUX)](/topic/flux) [Synapse (SYN)](/topic/synapse)
### Top Social Posts
Top posts by engagements in the last [--] hours

"Ectosomes step forward in -synuclein spread Nature Cell Biology Glucosylceramide accumulation — a hallmark of GBA1- and LRRK2-linked Parkinson’s disease — drives ectosome shedding from neurons. A study now shows that these plasma membrane-derived vesicles shuttle pathogenic α-synuclein across cells revealing ectosomes as an underappreciated route of pathology propagation in Parkinson’s disease"  
[X Link](https://www.nature.com/articles/s41556-026-01870-7)  2026-02-14T17:20Z 122.8K followers, [----] engagements


"Glucosylceramide-induced ectosomes propagate pathogenic -synuclein in Parkinsons disease Nature Cell Biology Jacquemyn et al. identify key lipid determinants controlling ectosome shedding from neurons. They find that ectosomes are a major route for the intercellular transport of misfolded α-synuclein with relevance to Parkinson’s disease pathology"  
[X Link](https://www.nature.com/articles/s41556-026-01871-6)  2026-02-12T17:26Z 2.1M followers, [----] engagements


"Intrinsic and niche-dependent metabolic regulation of haematopoietic stem cells and implications for leukaemogenesis Nature Cell Biology This Review presents the metabolic landscape of HSCs including the link of key metabolic features to self-renewal and differentiation and highlights how their alterations contribute to haematological disorders particularly leukaemogenesis"  
[X Link](https://www.nature.com/articles/s41556-026-01872-5)  2026-02-11T11:26Z 2.1M followers, [----] engagements


"💫NEW: @KraftLabFR @WilflingLab & co show that low-affinity cargoreceptor interactions promote #autophagy receptor mobility and condensation of the scaffold protein Atg11 to trigger initiation hub and phagophore formation. https://www.nature.com/articles/s41556-024-01572-y https://www.nature.com/articles/s41556-024-01572-y"  
[X Link](https://x.com/NatureCellBio/status/1891197974010642919)  2025-02-16T18:48Z 122.8K followers, [----] engagements


"💫NEW: Hsu et al. show that #mitochondria import blockage stress activates the ATP-dependent protease YME1L1 which degrades mitochondrial presequence translocase TIM23 subunits to promote cell growth. https://www.nature.com/articles/s41556-024-01571-z https://rdcu.be/d96cS https://www.nature.com/articles/s41556-024-01571-z https://rdcu.be/d96cS"  
[X Link](https://x.com/NatureCellBio/status/1891199152232542251)  2025-02-16T18:53Z 122.8K followers, [----] engagements


"💫NEW: @Sloan_Lab @CaitlinSojka & co analyse the transcriptomic & epigenomic landscape of human #astrocyte maturation and identify an epigenetically regulated intermediate state linked with aberrant development in #glioblastoma. https://www.nature.com/articles/s41556-024-01583-9 https://rdcu.be/eayMF https://www.nature.com/articles/s41556-024-01583-9 https://rdcu.be/eayMF"  
[X Link](https://x.com/anyuser/status/1892326150992482540)  2025-02-19T21:31Z 122.8K followers, [----] engagements


"☕@JingtaoGuo @LeqianYu & co characterize an intact Carnegie stage [--] #HumanEmbryo at single-cell resolution in a spatially resolved manner. https://bit.ly/3XhKW48 https://rdcu.be/ebq3Q https://bit.ly/3XhKW48 https://rdcu.be/ebq3Q"  
[X Link](https://x.com/anyuser/status/1894861130314448932)  2025-02-26T21:24Z 122.8K followers, [----] engagements


"☕@szmyd_radoslaw @TheCesareLab @RadOncDoc_Gee & co: #DNArepair pathways impact if cells with DNA lesions arrest in mitosis. Homologous recombination-driven double Holliday junction formation elicits mitotic #CellDeath & suppresses inflammatory signaling. https://bit.ly/4bfssHr https://bit.ly/4bfssHr"  
[X Link](https://x.com/anyuser/status/1894863874484285866)  2025-02-26T21:35Z 122.8K followers, [----] engagements


"🍰Read also the N&Vs article. https://bit.ly/4bk4ScD https://rdcu.be/ebq9N https://bit.ly/4bk4ScD https://rdcu.be/ebq9N"  
[X Link](https://x.com/anyuser/status/1894863876816019909)  2025-02-26T21:35Z 122.8K followers, [----] engagements


"☕Interested in how cells respond to #mitochondria #ProteinImport stress Read our Review article by Nikolaus Pfanner Fabian den Brave & Thomas Becker. https://bit.ly/41oGhyD https://rdcu.be/ecb3x https://bit.ly/41oGhyD https://rdcu.be/ecb3x"  
[X Link](https://x.com/anyuser/status/1897051405560766681)  2025-03-04T22:27Z 122.8K followers, [----] engagements


"☕Afonso et al. show that during #anaphase chromosome movement can be driven by large cytoplasmic flows. These dynein-dependent cytoplasmic flows scale with cell size slowing in smaller cells thereby scaling anaphase. https://bit.ly/4bpoMCU https://bit.ly/4bpoMCU"  
[X Link](https://x.com/anyuser/status/1897053282251759834)  2025-03-04T22:35Z 122.8K followers, [----] engagements


"🍰Interested in reading more about the study Here is the N&Vs article written by Nicoletta I. Petridou. https://bit.ly/4kniCrb https://rdcu.be/ecb3M https://bit.ly/4kniCrb https://rdcu.be/ecb3M"  
[X Link](https://x.com/anyuser/status/1897053284508348895)  2025-03-04T22:35Z 122.8K followers, [----] engagements


"☕Wang et al. profile the #translatome of #hematopoietic #StemCells (HSCs) and downstream progenitors and lineages. They identify the SNORD113114 cluster as a modulator of translation and self-renewal in HSCs. https://bit.ly/4i2xxVX https://rdcu.be/ecb3W https://bit.ly/4i2xxVX https://rdcu.be/ecb3W"  
[X Link](https://x.com/anyuser/status/1897054864703938582)  2025-03-04T22:41Z 122.8K followers, [----] engagements


"☕Oborsk-Oplov et al. report a conserved #mitochondria avoidance segment in the cytosolic ribosomal protein uS5 that prevents mistargeting of uS5 to the mitochondrial matrix and ensures cytosolic #ribosomal assembly. https://bit.ly/3EZV8bi https://rdcu.be/ecb32 https://bit.ly/3EZV8bi https://rdcu.be/ecb32"  
[X Link](https://x.com/anyuser/status/1897056566702182812)  2025-03-04T22:48Z 122.8K followers, [----] engagements


"🍰Interested in reading more about the study Here is the N&Vs article written by Kanda M. Borgognoni & Robin E. Stanley. https://bit.ly/4iq3iYV https://rdcu.be/ecb4a https://bit.ly/4iq3iYV https://rdcu.be/ecb4a"  
[X Link](https://x.com/anyuser/status/1897056568878989498)  2025-03-04T22:48Z 122.8K followers, [----] engagements


"☕@ScientistJoanna @RuggeroDavide & co perform a genome-wide CRISPRi screen and identify RBM42 as a ribosome-associated protein that modulates MYC translation and an #oncogenic mRNA program required for #PancreaticCancer growth. https://bit.ly/41rGfGb https://rdcu.be/ecb4e https://bit.ly/41rGfGb https://rdcu.be/ecb4e"  
[X Link](https://x.com/anyuser/status/1897058938300064186)  2025-03-04T22:57Z 122.8K followers, [----] engagements


"🍰Interested in reading more about the study Here is the N&Vs article written by Zainab Hussain & Mara H. Sherman. https://bit.ly/4knA1js https://rdcu.be/ecb4q https://bit.ly/4knA1js https://rdcu.be/ecb4q"  
[X Link](https://x.com/anyuser/status/1897058940464324686)  2025-03-04T22:57Z 122.8K followers, [----] engagements


"👋🏽A reminder to all our authors and readers that you can now find us and connect with us on Bluesky: @natcellbio.nature.com #Science #CellBiology #ScienceCommunication"  
[X Link](https://x.com/anyuser/status/1936193339134509487)  2025-06-20T22:43Z 122.8K followers, 14.1K engagements


"LIANA+ provides an all-in-one framework for cellcell communication inference - Nature Cell Biology Dimitrov et al. present LIANA+ a framework that unifies and extends approaches to study inter- and intracellular signalling from diverse mediators captured from single-cell spatially resolved and multi-omics data"  
[X Link](https://www.nature.com/articles/s41556-024-01469-w)  2024-09-02T00:00Z 125.6K followers, 29K engagements


"EPAC1 enhances brown fat growth and beige adipogenesis Nature Cell Biology Reverte-Salisa et al. show that in preadipocytes EPAC1 enhances brown adipose tissue growth and increases the function of thermogenic fat in obesogenic conditions. Activation of EPAC1 induces human brown adipocyte proliferation and differentiation"  
[X Link](https://www.nature.com/articles/s41556-023-01311-9)  2024-03-06T17:30Z 208.1M followers, [---] engagements


"H3K27 dimethylation dynamics reveal stepwise establishment of facultative heterochromatin in early mouse embryos - Nature Cell Biology Matsuwaka et al. show that JARID2-PRC2 initiates H3K27me2 deposition during the eight-cell-to-morula transition following H2AK119 mono-ubiquitylation deposition. It is also required for the subsequent H3K27me3 deposition at the blastocyst stage"  
[X Link](https://www.nature.com/articles/s41556-024-01553-1)  2024-10-31T00:00Z 125.3K followers, 41.1K engagements


"Gasdermins as evolutionarily conserved executors of inflammation and cell death - Nature Cell Biology Gasdermins are a family of proteins that form membrane pores and elicit pyroptosis. This Review discusses recent work highlighting their regulation and emerging biological roles including in non-lethal pore formation and host defence"  
[X Link](https://www.nature.com/articles/s41556-024-01474-z)  2024-08-26T00:00Z 2.1M followers, [----] engagements


"Perturbing TET2 condensation promotes aberrant genome-wide DNA methylation and curtails leukaemia cell growth - Nature Cell Biology Guo Hong et al. report that TET2 condensation maintains proper DNA demethylation at specific genomic loci which can be targeted to alter gene expression and impair leukaemia growth"  
[X Link](https://www.nature.com/articles/s41556-024-01496-7)  2024-09-09T00:00Z 125.6K followers, 12.2K engagements


"Solid tumour-induced systemic immunosuppression involves dichotomous myeloidB cell interactions Nature Cell Biology Hao Shen and colleagues identify and characterize two distinct types of myeloidB cell interaction that may signal solid tumour-induced immunosuppression and can correlate with complete responses to immunotherapy in patients with breast cancer"  
[X Link](https://www.nature.com/articles/s41556-024-01508-6)  2024-09-27T01:00Z 228.6M followers, [----] engagements


"ARF1 compartments direct cargo flow via maturation into recycling endosomes - Nature Cell Biology Stockhammer Adarska et al. describe ARF1 compartments as the site of adaptor- and clathrin-dependent post-Golgi sorting. Shedding of ARF1 and maturation into recycling endosomes drives sorting of secretory and endocytic recycling cargo"  
[X Link](https://www.nature.com/articles/s41556-024-01518-4)  2024-10-04T00:00Z 125.4K followers, 18.3K engagements


"HSF1 renders NK cells too stressed to respond - Nature Cell Biology The tumour microenvironment propagates stress responses in resident cells. In tumour-infiltrating natural killer (NK) cells the HSF1 transcription factor binds to mediators of effector function negatively regulating NK cytotoxicity. These findings provide important mechanistic insights that may enhance NK cell cancer therapy"  
[X Link](https://www.nature.com/articles/s41556-024-01472-1)  2024-09-02T00:00Z 125.6K followers, [--] engagements


"Spatiotemporal coordination of actin regulators generates invasive protrusions in cellcell fusion - Nature Cell Biology Lu et al. reveal the spatiotemporal coordination between two nucleation-promoting factors WAVE and N-WASP and two actin-bundling proteins dynamin and WIP in generating invasive protrusions at the mammalian myoblast fusogenic synapse"  
[X Link](https://www.nature.com/articles/s41556-024-01541-5)  2024-11-01T00:00Z 125.3K followers, [----] engagements


"Decapping enzyme 1A breaks X-chromosome symmetry by controlling Tsix elongation and RNA turnover - Nature Cell Biology Aeby et al. report that DCP1A negatively regulates Tsix RNA abundance by suppressing its transcriptional elongation and RNA stability thus contributing to X-chromosome inactivation"  
[X Link](https://www.nature.com/articles/s41556-020-0558-0)  2020-08-17T00:00Z 125.6K followers, [--] engagements


"p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells - Nature Cell Biology Majewska et al. show that p16-expressing senescent cells enhance the stability of the immune checkpoint PD-L1 by downregulating its proteasome-mediated ubiquitin-dependent degradation leading to their accumulation in ageing and chronic inflammation"  
[X Link](https://www.nature.com/articles/s41556-024-01465-0)  2024-08-05T00:00Z 125.6K followers, [--] engagements


"Blood-generating heart-forming organoids recapitulate co-development of the human haematopoietic system and the embryonic heart Nature Cell Biology Dardano et al. generate human pluripotent stem cell-derived cardiac organoids capable of undergoing endothelial-to-haematopoietic transition and producing haematopoietic cells"  
[X Link](https://www.nature.com/articles/s41556-024-01526-4)  2024-10-17T06:00Z 124.5K followers, [----] engagements


"Docking a flexible basket onto the core of the nuclear pore complex - Nature Cell Biology Stankunas and Khler define how the nucleoplasmic portion of the nuclear pore complex (NPC) the basket docks onto the NPC core by integrating AlphaFold-based interaction screens electron microscopy and membrane-templated reconstitutions"  
[X Link](https://www.nature.com/articles/s41556-024-01484-x)  2024-08-13T00:00Z 125.6K followers, [--] engagements


"Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells Nature Cell Biology McCreery Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes"  
[X Link](https://www.nature.com/articles/s41556-025-01767-x)  2025-09-30T19:18Z 121.8K followers, [--] engagements


"Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor - Nature Cell Biology Nicastro Brohe et al. find that the fatty acid synthesis intermediate malonyl-CoA inhibits mTORC1 showing mTORC1 senses the capacity of a cell to synthesise fatty acids and linking fatty acid generation with the overall biosynthetic output through mTORC1"  
[X Link](https://www.nature.com/articles/s41556-023-01198-6)  2023-08-10T00:00Z 125.6K followers, 11.2K engagements


"On the causal role of retromer-dependent endosomal recycling in Alzheimers disease - Nature Cell Biology Recent findings ranging from genetics to structural biology together with studies in human neurons animal models and patient brains implicate the retromer-dependent endosomal recycling pathway as both causal and common in Alzheimers disease"  
[X Link](https://www.nature.com/articles/s41556-023-01245-2)  2023-10-06T00:00Z 125.5K followers, [----] engagements


"Exploiting ferroptosis vulnerabilities in cancer - Nature Cell Biology Ferroptosis is a form of cell death that is characterized by morphological abnormalities of mitochondria and the overwhelming peroxidation of phospholipids. Certain tumours are susceptible to ferroptosis which could be exploited to treat cancers"  
[X Link](https://www.nature.com/articles/s41556-024-01425-8)  2024-06-10T00:00Z 2.1M followers, [----] engagements


"Chromatin remodelling in damaged intestinal crypts orchestrates redundant TGF and Hippo signalling to drive regeneration - Nature Cell Biology Using deep single-nucleus multi-omics profiling Fink et al. report transition states between crypt epithelial cells and a revival stem cell lineage. They find that the TGF and Hippo signalling pathways cooperatively drive intestinal regeneration"  
[X Link](https://www.nature.com/articles/s41556-024-01550-4)  2024-11-15T00:00Z 125.1K followers, [----] engagements


"A subset of transposable elements as mechano-response enhancer elements in controlling human embryonic stem cell fate Nature Cell Biology Sun et al. identify a subset of transposable elements that serve as mechano-response enhancer elements that control gene expression and human stem cell fate"  
[X Link](https://www.nature.com/articles/s41556-025-01770-2)  2025-09-17T20:32Z 208.1M followers, [----] engagements


"Hepatocellular senescence induces multi-organ senescence and dysfunction via TGF - Nature Cell Biology Kiourtis et al. show that liver senescence triggers senescence and dysfunction in other organs through TGF secretion from the liver"  
[X Link](https://www.nature.com/articles/s41556-024-01543-3)  2024-11-13T00:00Z 125K followers, 10.7K engagements


"Blebbisomes are large organelle-rich extracellular vesicles with cell-like properties Nature Cell Biology Jeppesen Sanchez et al. identify blebbisomes as large membrane-enclosed vesicles containing organelles and secreted by cells. Blebbisomes can both secrete and internalize exosomes and microvesicles"  
[X Link](https://www.nature.com/articles/s41556-025-01621-0)  2025-02-22T08:34Z 2.1M followers, 61.8K engagements


"The ETS transcription factor ETV6 constrains the transcriptional activity of EWSFLI to promote Ewing sarcoma - Nature Cell Biology Independent but complementary studies from Vakoc and Stegmaier identify and characterize a role for ETV6 in counteracting the transcriptional activity of EWSFLI during Ewing sarcoma development which may be targeted for therapeutic benefits"  
[X Link](https://www.nature.com/articles/s41556-022-01059-8)  2023-01-19T00:00Z 208.1M followers, [---] engagements


"An overview of contemporary theories of ageing Nature Cell Biology This Review provides an overview of modern mechanistic theories and critically examines two main groups of ageing theories—error and program based—in the context of ageing patterns genetic manipulations and longevity drugs"  
[X Link](https://www.nature.com/articles/s41556-025-01698-7)  2025-07-01T09:42Z 2.1M followers, 41.7K engagements


"Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis - Nature Cell Biology Zhou et al. describe an intracellular transport pathway of low-density lipoprotein (LDL)LDL receptor from the plasma membrane that bypasses lysosomes and delivers cholesterol to mitochondria for steroidogenesis"  
[X Link](https://www.nature.com/articles/s41556-023-01160-6)  2023-06-05T00:00Z 125.2K followers, 27.5K engagements


"Emerging connections between myelin and Alzheimers disease Nature Cell Biology Recent literature has explored the contributions of oligodendrocytes and myelin dysfunction to Alzheimer’s disease. Here we discuss emerging evidence that oligodendrocytes may directly contribute to disease pathology and progression"  
[X Link](https://www.nature.com/articles/s41556-025-01701-1)  2025-08-01T15:35Z 228.6M followers, [----] engagements


"FOXO1-mediated lipid metabolism maintains mammalian embryos in dormancy - Nature Cell Biology van der Weijden et al. perform genomic proteomic and metabolic analyses and find that FOXO1-mediated fatty acid oxidation maintains mouse embryos in diapause"  
[X Link](https://www.nature.com/articles/s41556-023-01325-3)  2024-01-04T00:00Z 125.1K followers, [----] engagements


"Shell protein composition specified by the lncRNA NEAT1 domains dictates the formation of paraspeckles as distinct membraneless organelles - Nature Cell Biology Takakuwa Yamazaki et al. show that the long noncoding RNA NEAT1 domains specify a set of proteins that localize to the outer shell and distinguish nuclear speckles from paraspeckles to preserve their structural identity"  
[X Link](https://www.nature.com/articles/s41556-023-01254-1)  2023-11-06T00:00Z 125K followers, [----] engagements


"MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death Nature Cell Biology Nguyen Collier et al. find a mitochondrialysosome inflammatory pathway regulated by the SUMO E3 ligase MAPL which promotes vesicular mtDNA transport to lysosomes and subsequent gasdermin-dependent lysosomal permeabilization to activate pyroptosis"  
[X Link](https://www.nature.com/articles/s41556-025-01774-y)  2025-10-13T17:44Z 228.6M followers, 10.8K engagements


"Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition - Nature Cell Biology Yuzhalin et al. report that astrocyte-mediated upregulation of Cdk5 in metastatic breast cancer cells inhibits MHC-I expression on the cell surface thereby enabling escape from killing by CD8+ T cells and facilitating brain metastasis"  
[X Link](https://www.nature.com/articles/s41556-024-01509-5)  2024-09-20T00:00Z 125.6K followers, [----] engagements


"FMRP regulates MFF translation to locally direct mitochondrial fission in neurons - Nature Cell Biology Fenton et al. show that FMRP granules dock at the mitochondrial midzone in a Rab7-dependent manner in axons and dendrites where they promote local MFF synthesis and fission at the mitochondrial midzone"  
[X Link](https://www.nature.com/articles/s41556-024-01544-2)  2024-11-15T00:00Z 125.1K followers, 10.7K engagements


"Distinct H3K9me3 heterochromatin maintenance dynamics govern different gene programmes and repeats in pluripotent cells - Nature Cell Biology Zhang et al. uncover different dynamics underlying the maintenance and regulation of H3K9me3-enriched heterochromatin domains in mouse embryonic stem cells and propose that loss of H3K9me3 occurs through two distinct dynamic modes: passive dilution and active removal"  
[X Link](https://www.nature.com/articles/s41556-024-01547-z)  2024-10-31T00:00Z 125.1K followers, 10.9K engagements


"Basic science is not just a foundation Nature Cell Biology Intellectual freedom for scientists unconstrained by commercial interests and direct application fuels unexpected discoveries. Curiosity-driven basic science has yielded a deeper understanding of how life forms develop and function in their environment and has had wide implications for health and our planet. Investing in this is vital for scientific progress and is worth protecting in a democracy"  
[X Link](https://www.nature.com/articles/s41556-023-01308-4)  2024-01-17T12:49Z 208.1M followers, [---] engagements


"Recording morphogen signals reveals mechanisms underlying gastruloid symmetry breaking - Nature Cell Biology Toettcher McNamara and colleagues use synthetic signal-recording gene circuits on mouse gastruloids and find that cell sorting rearranges patchy domains of Wnt activity into a single pole which defines the gastruloid anteriorposterior axis"  
[X Link](https://www.nature.com/articles/s41556-024-01521-9)  2024-10-02T00:00Z 125.6K followers, [----] engagements


"Mitochondrial heterogeneity and adaptations to cellular needs - Nature Cell Biology Granath-Panelo and Kajimura review emerging evidence of mitochondrial heterogeneity in different contexts and discuss how mitochondrial malleability contributes to cell fate determination and tissue remodelling"  
[X Link](https://www.nature.com/articles/s41556-024-01410-1)  2024-05-16T00:00Z 2.1M followers, [----] engagements


"Single-cell multi-omics sequencing of human spermatogenesis reveals a DNA demethylation event associated with male meiotic recombination - Nature Cell Biology Huang Li An Yang Cui et al. perform a single-cell multi-omics analysis of human spermatogenesis and identify a DNA demethylation event upon meiosis initiation which is associated with meiotic recombination"  
[X Link](https://www.nature.com/articles/s41556-023-01232-7)  2023-09-18T00:00Z 125.5K followers, [----] engagements


"Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments Nature Cell Biology Janiszewska et al. show that minor subpopulations expressing IL11 and FIGF in breast cancer cells promote metastasis through altering local and systemic tumour microenvironments including neutrophils"  
[X Link](https://www.nature.com/articles/s41556-019-0346-x)  2019-07-18T10:12Z 124.5K followers, [--] engagements


"Building the epigenetic fortress with PRC2.2 - Nature Cell Biology How heterochromatin is established de novo in early embryos is unknown. A study now shows that the sequential recruitment of the key regulator JARID2 recruits PRC2.2 to H2AK119ub and ensures proper H3K27me2/3 deposition. This prevents premature enhancer activation which is crucial for gene regulation and lineage specification"  
[X Link](https://www.nature.com/articles/s41556-024-01551-3)  2024-10-31T00:00Z 125.6K followers, [---] engagements


"Spindle architecture constrains karyotype evolution - Nature Cell Biology Helsen et al. use experimental evolution and chromosome engineering to probe the link between karyotype changes and the cell division machinery. They conclude that spindle organization dictates the available trajectories for karyotype evolution"  
[X Link](https://www.nature.com/articles/s41556-024-01485-w)  2024-08-08T00:00Z 125.6K followers, [--] engagements


"Chaperone-mediated autophagy regulates neuronal activity by sex-specific remodelling of the synaptic proteome Nature Cell Biology Khawaja et al. show sex-specific differences in neuronal-activity regulation by chaperone-mediated autophagy and that loss of chaperone-mediated autophagy leads to defective neuronal physiology and increased seizure susceptibility linking chaperone-mediated autophagy to neuronal excitability"  
[X Link](https://www.nature.com/articles/s41556-025-01771-1)  2025-10-16T14:38Z 208.1M followers, [---] engagements


"Telomere dysfunction in ageing and age-related diseases Nature Cell Biology Rossiello et al. review the contributions of telomere shortening and/or dysfunction to ageing and a broad spectrum of age-associated human diseases"  
[X Link](https://www.nature.com/articles/s41556-022-00842-x)  2025-10-11T17:22Z 2.1M followers, 70.4K engagements


"Plasma membrane curvature regulates the formation of contacts with the endoplasmic reticulum - Nature Cell Biology Yang et al. show that plasma membrane curvature promotes the site-specific formation of contacts with the endoplasmic reticulum through junctophilin-2 tethers in cardiomyocytes"  
[X Link](https://www.nature.com/articles/s41556-024-01511-x)  2024-09-17T00:00Z 125.6K followers, 18.4K engagements


"Specialized post-arterial capillaries facilitate adult bone remodelling - Nature Cell Biology Mohanakrishnan et al. identify a distinct subset of post-arterial capillaries termed type R. They show that type R capillaries contribute to trabecular bone formation in the diaphysis and respond to anti-osteoporosis treatments"  
[X Link](https://www.nature.com/articles/s41556-024-01545-1)  2024-11-11T00:00Z 125.2K followers, [----] engagements


"NEW ONLINE: We spoke to Kara McKinley (@karalmckinley) assistant professor of stem cell and regenerative biology at @HSCRB about her career and goals for our research community. Find the Q&A here: https://www.nature.com/articles/s41556-022-01083-8 https://rdcu.be/c4poh https://www.nature.com/articles/s41556-022-01083-8 https://rdcu.be/c4poh"  
[X Link](https://x.com/NatureCellBio/status/1619800765484376064)  2023-01-29T20:52Z 124.5K followers, 62.3K engagements


"☕NEW: Zhou et al. describe an intracellular transport pathway of low-density lipoprotein (LDL)LDL receptor from the plasma membrane that bypasses lysosomes and delivers cholesterol to mitochondria for steroidogenesis. https://www.nature.com/articles/s41556-023-01160-6 https://rdcu.be/demjw https://www.nature.com/articles/s41556-023-01160-6 https://rdcu.be/demjw"  
[X Link](https://x.com/NatureCellBio/status/1668351785411436570)  2023-06-12T20:17Z 125.2K followers, 19.4K engagements


"🧋NEW: Chung et al. identify the Troyer syndrome protein spartin as a #lipophagy receptor for #lipiddroplet clearance in vitro and in vivo. @TobiWalther @BobFarese @FandWLab @JeeyunC @MCB_Harvard @SKI_CellBiology"  
[X Link](https://x.com/NatureCellBio/status/1681279274303537154)  2023-07-19T08:18Z 122.4K followers, 16.9K engagements


"🧋NEW: Nicastro Brohe et al. find that #malonylCoA inhibits #mTORC1 thus linking #fattyacid generation with the overall biosynthetic output through mTORC1. @Raf_Nic @laura_brohee @LabVanni @TelemanLab @CDV1893 @DemetriadesLab https://www.nature.com/articles/s41556-023-01198-6 https://www.nature.com/articles/s41556-023-01198-6"  
[X Link](https://x.com/NatureCellBio/status/1692230488243458247)  2023-08-17T17:42Z 125.6K followers, 11.2K engagements


"🍹NEW: Romanauska and Khler manipulate the levels of endogenously produced saturated acyl chains in yeast and show that #NuclearEnvelope and #NuclearPoreComplex function are uniquely sensitive to #lipid acyl chain unsaturation. @MaxPerutzLabs"  
[X Link](https://x.com/NatureCellBio/status/1693967033992446137)  2023-08-22T12:43Z 121.7K followers, [----] engagements


"🍹NEW: @bernstein_lab & co show that macroH2A deficiency in #CancerAssociatedFibroblasts alters #chromatinlooping and #inflammatory gene expression and limits the #AntiTumor response in #melanoma. @TischCancer @IcahnMountSinai @MelanomaReAlli"  
[X Link](https://x.com/NatureCellBio/status/1698740530752991617)  2023-09-04T16:51Z 121.8K followers, [----] engagements


"🍹NEW: Surani Irie & co show that #DMRT1 induction in #PrimordialGermCell-like cells triggers germline commitment but suppresses #pluripotency genes thus promoting the onset of #gametogenesis. @GurdonInstitute"  
[X Link](https://x.com/NatureCellBio/status/1704839113764184205)  2023-09-21T12:44Z 121.7K followers, [----] engagements


"🍹NEW: Huang Li An Yang Cui et al. perform a #singlecell #multiomics analysis of human #spermatogenesis and identify a DNA demethylation event upon #meiosis initiation which is associated with #MeioticRecombination. https://www.nature.com/articles/s41556-023-01232-7 https://rdcu.be/dmW9M https://www.nature.com/articles/s41556-023-01232-7 https://rdcu.be/dmW9M"  
[X Link](https://x.com/NatureCellBio/status/1706295417816670339)  2023-09-25T13:11Z 125.5K followers, [----] engagements


"🍹NEW: @yamashitaflylab @zamore_lab & co show that Y-linked Su(Ste) #piRNAs are produced via 5-to-3 phased-biogenesis initiated by maternally deposited 1360/Hoppel-derived piRNAs silencing Ste in male #germline. @IGainetdinov @WhiteheadInst @MITBiology"  
[X Link](https://x.com/NatureCellBio/status/1706815969492959343)  2023-09-26T23:40Z 122.4K followers, [----] engagements


"🍹NEW: Bernab-Rubio et al. report that #dedifferentiation of Gata6+ #EpidermalCells occurs during #woundhealing or mechanical expansion of the #epidermis through a Myc-dependent process that resembles reversal of differentiation. @KCLstemcells https://www.nature.com/articles/s41556-023-01234-5 https://www.nature.com/articles/s41556-023-01234-5"  
[X Link](https://x.com/NatureCellBio/status/1707497246642540812)  2023-09-28T20:47Z 125.6K followers, [----] engagements


"🍹NEW:@ArdehaliHossein & co find a role for the #HistoneDemethylase KDM3B in sensing #ironlevels and regulating #mTORC1 via #transcriptional repression of mTORC1 pathway components. @nu_fcvrri @NUFeinbergMed @NorthwesternMed @NUMSTP https://www.nature.com/articles/s41556-023-01225-6 https://rdcu.be/dnhYk https://www.nature.com/articles/s41556-023-01225-6 https://rdcu.be/dnhYk"  
[X Link](https://x.com/NatureCellBio/status/1707504621982204119)  2023-09-28T21:16Z 125.5K followers, [----] engagements


"🍹NEW: Timms Mena et al. present a multiplex #CRISPR #screeningplatform capable of assigning #E3ligases to their substrates and degrons at scale. #CRISPRscreening"  
[X Link](https://x.com/NatureCellBio/status/1707779640490676318)  2023-09-29T15:29Z 122.4K followers, [----] engagements


"☕NEW: Zhang et al. report curved adhesions which are #integrin-based adhesions formed in response to membrane curvatures that can be imposed by the overlying #extracellularmatrix fibre geometry. @cuilab_chem @StanfordUChem @Stanford_CHEMH @BianxiaoC"  
[X Link](https://x.com/NatureCellBio/status/1708963076140089558)  2023-10-02T21:52Z 121.7K followers, [----] engagements


"☕NEW: Churchman & co share #CRISPRscreen for factors altering the levels of [--] dual-genome-encoded #ComplexIV subunits and identify PREPL and NME6 as genes that connect #MitochondrialMetabolism to #mtDNA expression. @fiddle @GyPrak"  
[X Link](https://x.com/NatureCellBio/status/1709553146916143352)  2023-10-04T12:56Z 121.5K followers, [----] engagements


"🍵Read our new Comment by Small & co on #retromer-dependent #endosomal recycling in #Alzheimersdisease. PDF: https://www.nature.com/articles/s41556-023-01245-2 https://rdcu.be/dn6Le https://www.nature.com/articles/s41556-023-01245-2 https://rdcu.be/dn6Le"  
[X Link](https://x.com/NatureCellBio/status/1711358078879170720)  2023-10-09T12:28Z 125.5K followers, [----] engagements


"☕NEW: Lusk King (@LuskingL @Plusk4u) & co find a grommet-like role for #ESCRTs. The grommet works with #spindle pole body components that establish a #diffusionbarrier to maintain compartmentalization. @NicholasAder @YaleCellBio"  
[X Link](https://x.com/NatureCellBio/status/1711362794199581164)  2023-10-09T12:47Z 122.4K followers, [----] engagements


"☕NEW: @YoshiakiKubota Takubo & co perform #SingleCellRNASequencing and identify a #BoneMarrow #EndothelialCell subtype that contributes to the acquisition of bone strength and offers a distinct #HematopoieticStemCell niche. @Keio_univ_PR"  
[X Link](https://x.com/NatureCellBio/status/1712817922781921493)  2023-10-13T13:09Z 121.8K followers, [----] engagements


"🍵Read our new Comment by @CreweLab @SnigdhaTiash and @BrestoffLab on #MitochondriaTransfer:"  
[X Link](https://x.com/NatureCellBio/status/1717511398857879895)  2023-10-26T12:00Z 121.3K followers, [----] engagements


"☕NEW: Wang Chen & co report that the secretory coat protein complex COPII undergoes liquidliquid #PhaseSeparation that is tuned by #manganese in the cytosol to impact #lipoprotein secretion"  
[X Link](https://x.com/NatureCellBio/status/1721522489388331068)  2023-11-06T13:38Z 121.5K followers, 17.6K engagements


"☕NEW: Hicks (@Mic_Hicks) Pyle (@apyle) & co report in an Open Access study that human regenerating #myofibres expressing #ACTC1 substantially contribute to supporting #PAX7+ #skeletalmuscle progenitor cells. #MuscleRegeneration"  
[X Link](https://x.com/NatureCellBio/status/1722609735872938015)  2023-11-09T13:39Z 121.5K followers, [----] engagements


"☕NEW: Through a #CRISPR-activation screen Ravid Lustig et al. show that #GATA transcription factors activate long-range Xist enhancers to upregulate Xist expression and initiate #Xchromosome inactivation in early #MouseEmbryos. @EddaGSchulz @MPI_MolGen"  
[X Link](https://x.com/NatureCellBio/status/1724417896493826260)  2023-11-14T13:23Z 122.4K followers, [----] engagements


"☕NEW: Takakuwa Yamazaki et al. show that the #LongnoncodingRNA #NEAT1 domains specify a set of proteins that localize to the outer shell and distinguish #nuclearspeckles from #paraspeckles to preserve their structural identity. https://www.nature.com/articles/s41556-023-01254-1 https://rdcu.be/dq96p https://www.nature.com/articles/s41556-023-01254-1 https://rdcu.be/dq96p"  
[X Link](https://x.com/NatureCellBio/status/1724770964733346246)  2023-11-15T12:46Z 125K followers, [----] engagements


"🎁Interested in reading more about the study Here is the N&Vs article written by Miroslav Dundr and Jeremy D. Schmit: https://www.nature.com/articles/s41556-023-01265-y https://rdcu.be/dq96V https://www.nature.com/articles/s41556-023-01265-y https://rdcu.be/dq96V"  
[X Link](https://x.com/NatureCellBio/status/1724770967799419062)  2023-11-15T12:46Z 125K followers, [----] engagements


"☕In this issue: Through a #CRISPR-activation screen @EddaGSchulz & co show that #GATA transcription factors activate long-range Xist enhancers to upregulate Xist expression and initiate #Xchromosome inactivation in early #MouseEmbryos"  
[X Link](https://x.com/NatureCellBio/status/1727416661165101446)  2023-11-22T20:00Z 121.8K followers, [----] engagements


"💫NEW: Tang & co from @Westlake_Uni describe #mitopherogenesis: the secretion of #mitochondria in mitophers during #SpermDevelopment in C. elegans which controls the #mitochondrial pool and ensure #fertility. #ExtracellularVesicles"  
[X Link](https://x.com/NatureCellBio/status/1728897341527335219)  2023-11-26T22:03Z 121.7K followers, [----] engagements


"💫NEW: @DLawsonlab & co identify and characterize a #tumour-suppressive role for #microglia that mediates a pro-inflammatory response to restrict brain #metastasis in #BreastCancer. #CancerResearch"  
[X Link](https://x.com/NatureCellBio/status/1729325739248427020)  2023-11-28T02:26Z 121.7K followers, 11K engagements


"💫NEW: @SJMorrison_ @Bo_Shen_ & co report that #LeptinReceptor+ #StromalCells sustain #BoneMarrow nerves by producing NGF. Upon myeloablation nerves promote marrow regeneration by increasing the production of growth factors by leptin receptor+ cells"  
[X Link](https://x.com/NatureCellBio/status/1730938617214759227)  2023-12-02T13:15Z 121.7K followers, [----] engagements


"☕🎄In this issue: Munk et al. show that exogenous NAD+ but not its precursors induces metabolic changes in #mitochondria affecting #nucleotide metabolism with impacts on genomic #DNAsynthesis and #GenomeIntegrity. @cancer_dk"  
[X Link](https://x.com/NatureCellBio/status/1735295827697115491)  2023-12-14T13:49Z 121.8K followers, [----] engagements


"💫NEW: @FilipovskaLab & co use 3D cell reconstruction of focused ion beam scanning electron #microscopy data and #multiomics to show that ether-#lipid #metabolism regulates inter-organelle biogenesis and dynamics"  
[X Link](https://x.com/NatureCellBio/status/1742179183944417654)  2024-01-02T13:41Z 121.7K followers, [----] engagements


"🎂Nature Cell Biology is turning [--] and we are celebrating [--] years of excellence in #cellbiology with a series of commissioned content and a collection of research articles across the journals broad scope. Read the Editorial:"  
[X Link](https://x.com/NatureCellBio/status/1747983759335461049)  2024-01-18T14:06Z 122.4K followers, [----] engagements


"☕In this issue: @FilipovskaLab & co use 3D cell reconstruction of focused ion beam scanning electron #microscopy data and #multiomics to show that ether-#lipid #metabolism regulates inter-organelle biogenesis and dynamics"  
[X Link](https://x.com/NatureCellBio/status/1751061461399420985)  2024-01-27T01:56Z 121.8K followers, [----] engagements


"☕In this issue: Son et al. show that #AMPK- & PP2A-dependent #p300 nucleocytoplasmic shuttling regulates #mTORC1 activity in response to nutrient status. Models of HutchinsonGilford #progeria display increased cytoplasmic p300 and mTORC1 hyperactivation"  
[X Link](https://x.com/NatureCellBio/status/1764470821194465548)  2024-03-04T02:00Z 122.9K followers, 13K engagements


"📢Join us in this Nature conference on September 23-25 in Beijing Register now for the '#Mitochondria and #Immunity' meeting organized by @NatureCellBio @NatMetabolism @NatImmunol and Nankai University. Abstract submission deadline: Aug [--] [----] https://conferences.nature.com/event/Mitochondria/summary https://conferences.nature.com/event/Mitochondria/summary"  
[X Link](https://x.com/NatureCellBio/status/1775875262594400658)  2024-04-04T13:17Z 123.3K followers, [----] engagements


"☕In this issue: New Review article by @OlzmannLab & @alymathiowetz on #LipidDroplet biogenesis mechanisms their role in fatty acid flux in lipotoxicity and #CellDeath and more 👉🏽Read here: https://rdcu.be/dEmCO https://www.nature.com/articles/s41556-024-01364-4 https://rdcu.be/dEmCO https://www.nature.com/articles/s41556-024-01364-4"  
[X Link](https://x.com/NatureCellBio/status/1778215134005211453)  2024-04-11T00:15Z 123.3K followers, 15.2K engagements


"A study by @Marteijnlab @oncodeinstitute @MolecularGenet3 & co: https://www.nature.com/articles/s41556-024-01394-y https://www.nature.com/articles/s41556-024-01394-y"  
[X Link](https://x.com/NatureCellBio/status/1785284319482712195)  2024-04-30T12:25Z 123.5K followers, [----] engagements


"☕In this issue: A Comment on #VolumeElectronMicroscopy standards in sample preparation and image acquisition for enhanced reproducibility and data reuse. https://www.nature.com/articles/s41556-024-01381-3 https://rdcu.be/dGMhZ https://www.nature.com/articles/s41556-024-01381-3 https://rdcu.be/dGMhZ"  
[X Link](https://x.com/NatureCellBio/status/1786922508911853800)  2024-05-05T00:55Z 123.6K followers, [----] engagements


"💫NEW by Palmulli Couty et al: CD63 promotes #cholesterol accumulation in intraluminal vesicles (ILVs) at the expense of retrieval from #endosomes; cholesterol stored in ILVs and exosomes is recovered in an NPC1-dependent manner. https://www.nature.com/articles/s41556-024-01432-9 https://rdcu.be/dNCzQ https://www.nature.com/articles/s41556-024-01432-9 https://rdcu.be/dNCzQ"  
[X Link](https://x.com/NatureCellBio/status/1811869465446924521)  2024-07-12T21:05Z 124.4K followers, [----] engagements


"💫2 new studies by Agarwal et al. and Wang et al. show that vesicle-associated membrane protein [--] (VAMP2) interacts with and regulates #AlphaSynuclein #BiomolecularCondensation affecting -synuclein function which may prevent pathological amyloid aggregation. 👇🏾see below:"  
[X Link](https://x.com/NatureCellBio/status/1815434803145027613)  2024-07-22T17:12Z 124.4K followers, [----] engagements


"💫NEW: Sun Tao Han et al. identify the Rabs involved in unconventional protein secretion mediated by TMED10 and in ERGolgi intermediate compartment organization. https://www.nature.com/articles/s41556-024-01445-4 https://rdcu.be/dOAv5 https://www.nature.com/articles/s41556-024-01445-4 https://rdcu.be/dOAv5"  
[X Link](https://x.com/NatureCellBio/status/1815507116335227112)  2024-07-22T22:00Z 124.5K followers, [----] engagements


"💫NEW: Wu & co report that upon ultraviolet-C radiation full-length #GSDME can induce #pyroptosis without cleavage. https://www.nature.com/articles/s41556-024-01463-2 https://rdcu.be/dQQA5 https://www.nature.com/articles/s41556-024-01463-2 https://rdcu.be/dQQA5"  
[X Link](https://x.com/NatureCellBio/status/1823426525632348488)  2024-08-13T18:28Z 124.2K followers, [----] engagements


"💫NEW: Schwab Rao et al. report that Zeb1 mediates enhanced #ferroptosis sensitivity in #cancer cells after #EMT activation associated with altered expression of selected lipogenic enzymes and an subsequent increase in the PUFA:MUFA ratio. https://www.nature.com/articles/s41556-024-01464-1 https://www.nature.com/articles/s41556-024-01464-1"  
[X Link](https://x.com/NatureCellBio/status/1824006567898779879)  2024-08-15T08:53Z 125.6K followers, [----] engagements


"💫NEW: @JuliaMMagdalena @amitmechaging @KrizhanovskyLab & co show that #p16-expressing #senescent cells enhance PD-L1 stability by downregulating its proteasome-mediated degradation leading to their accumulation in aging and chronic inflammation. https://www.nature.com/articles/s41556-024-01465-0 https://www.nature.com/articles/s41556-024-01465-0"  
[X Link](https://x.com/NatureCellBio/status/1830646620687360123)  2024-09-02T16:39Z 125.6K followers, [----] engagements


"💫NEW: Guo Hong et al. report that #TET2 condensation maintains proper #DNAdemethylation at specific genomic loci which can be targeted to alter gene expression and impair #leukemia growth. @Yun_Nancy_Huang @ZhouLaboratory https://www.nature.com/articles/s41556-024-01496-7 https://rdcu.be/dUBQM https://www.nature.com/articles/s41556-024-01496-7 https://rdcu.be/dUBQM"  
[X Link](https://x.com/NatureCellBio/status/1837467060114231460)  2024-09-21T12:21Z 125.6K followers, 12.2K engagements


"💫NEW: Yang et al show that #PlasmaMembrane curvature promotes the site-specific formation of contacts with the #EndoplasmicReticulum through junctophilin-2 tethers in #cardiomyocytes. @cuilab_chem @StanfordUChem @Stanford_CHEMH @BianxiaoC @YangYang0511 https://www.nature.com/articles/s41556-024-01511-x https://www.nature.com/articles/s41556-024-01511-x"  
[X Link](https://x.com/NatureCellBio/status/1839643401270292945)  2024-09-27T12:29Z 125.6K followers, [----] engagements


"💫NEW: Yuzhalin et al. show that #astrocyte-mediated Cdk5 upregulation in metastatic #BreastCancer inhibits MHC-I cell surface expression thus enabling escape from killing by #CD8T cells and facilitating #BrainMetastasis. https://www.nature.com/articles/s41556-024-01509-5 https://rdcu.be/dVNgf https://www.nature.com/articles/s41556-024-01509-5 https://rdcu.be/dVNgf"  
[X Link](https://x.com/NatureCellBio/status/1841508240162529712)  2024-10-02T15:59Z 125.6K followers, [----] engagements


"💫NEW: Bose (@MainakB78580463) Rankovic et al. show that a specific RNARNA kissing-loop interaction plays a crucial role in driving #BiomolecularCondensation of #ribonucleoprotein granules in the Drosophila #germline. @embl https://www.nature.com/articles/s41556-024-01519-3 https://www.nature.com/articles/s41556-024-01519-3"  
[X Link](https://x.com/NatureCellBio/status/1841768420917846400)  2024-10-03T09:13Z 124.3K followers, [----] engagements


"💫NEW by @toettch @h4rrymcnamara & co: synthetic signal-recording gene circuits on mouse #gastruloids show that cell sorting rearranges patchy domains of Wnt activity into a single pole that defines the anteriorposterior axis. https://www.nature.com/articles/s41556-024-01521-9 https://rdcu.be/dVTQc https://www.nature.com/articles/s41556-024-01521-9 https://rdcu.be/dVTQc"  
[X Link](https://x.com/NatureCellBio/status/1841818231683874848)  2024-10-03T12:31Z 125.6K followers, [----] engagements


"💫NEW: @fran_bottanelli @A_STEDhammer @petiaadarska & co describe ARF1 compartments as the site of adaptor- and clathrin-dependent post-#Golgi sorting. @fubcp @FU_Berlin https://www.nature.com/articles/s41556-024-01518-4 https://www.nature.com/articles/s41556-024-01518-4"  
[X Link](https://x.com/NatureCellBio/status/1844720857509433558)  2024-10-11T12:45Z 125.6K followers, [----] engagements


"💫NEW: Dardano et al. generate human pluripotent stem cell-derived #cardiac #organoids capable of undergoing endothelial-to-hematopoietic transition and producing #hematopoietic cells. https://www.nature.com/articles/s41556-024-01526-4 https://www.nature.com/articles/s41556-024-01526-4"  
[X Link](https://x.com/NatureCellBio/status/1846793392459538633)  2024-10-17T06:00Z 124.4K followers, [----] engagements


"💫NEW: @DemetriadesLab @stephalcantara @DAngelidaki & co dissect the spatial separation of #mTORC1 activation and signaling. Differentially localized mTORC1 complexes phosphorylate distinct substrates in response to different amino acid supplies. https://www.nature.com/articles/s41556-024-01523-7 https://www.nature.com/articles/s41556-024-01523-7"  
[X Link](https://x.com/NatureCellBio/status/1846893926675841520)  2024-10-17T12:40Z 125.5K followers, [----] engagements


"💫NEW: Zaret & co uncover different dynamics underlying the maintenance & regulation of #H3K9me3-enriched heterochromatin domains in mouse #ESCs: loss of H3K9me3 occurs through [--] distinct modes: passive dilution & active removal. https://www.nature.com/articles/s41556-024-01547-z https://rdcu.be/dZPNu https://www.nature.com/articles/s41556-024-01547-z https://rdcu.be/dZPNu"  
[X Link](https://x.com/NatureCellBio/status/1856330858942345504)  2024-11-12T13:39Z 125.1K followers, [----] engagements


"💫NEW: @EChenLab & co reveal spatiotemporal coordination between [--] nucleation-promoting factors WAVE & N-WASP and [--] actin-bundling proteins dynamin & WIP in generating invasive protrusions at the #myoblast fusogenic synapse. https://www.nature.com/articles/s41556-024-01541-5 https://rdcu.be/d0cTg https://www.nature.com/articles/s41556-024-01541-5 https://rdcu.be/d0cTg"  
[X Link](https://x.com/NatureCellBio/status/1857056703251988529)  2024-11-14T13:43Z 125.2K followers, [----] engagements


"👋🏻Our November issue's out Cover: Imaging #Ovulation 👉🏼Comments on #embryo models & #MembraneContactSites 🔬on: #PlasmaMembrane #endosomes #CellDeath #metabolism #mTOR #BiomolecularCondensation #gastruloids #organoids #ProteinQualityControl & more https://www.nature.com/ncb/volumes/26/issues/11 https://www.nature.com/ncb/volumes/26/issues/11"  
[X Link](https://x.com/NatureCellBio/status/1858501004867547565)  2024-11-18T13:22Z 125.1K followers, 18.2K engagements


"💫NEW: @CKiourtis et al. show that #liver #senescence triggers senescence and dysfunction in other organs through TGF secretion from the liver. @CRUK_SI @EdinUni_IRR @EdinUni_CIR @krikirschner @RajivJalan1 #endocrinesenescence https://www.nature.com/articles/s41556-024-01543-3 https://www.nature.com/articles/s41556-024-01543-3"  
[X Link](https://x.com/NatureCellBio/status/1864313808145056227)  2024-12-04T14:20Z 125K followers, [----] engagements


"💫NEW: Fenton et al. show that FMRP granules dock at the mitochondrial midzone in a Rab7-dependent manner in axons and dendrites where they promote local MFF synthesis and fission at the #mitochondrial midzone. https://www.nature.com/articles/s41556-024-01544-2 https://www.nature.com/articles/s41556-024-01544-2"  
[X Link](https://x.com/NatureCellBio/status/1867467779604922404)  2024-12-13T07:13Z 125.1K followers, [----] engagements


"💫NEW: Fink et al. report transition states between crypt epithelial cells and a revival stem cell lineage. They find that the TGF and Hippo signalling pathways cooperatively drive #intestinal #regeneration. https://www.nature.com/articles/s41556-024-01550-4 https://rdcu.be/d3pp5 https://www.nature.com/articles/s41556-024-01550-4 https://rdcu.be/d3pp5"  
[X Link](https://x.com/NatureCellBio/status/1867563121130217976)  2024-12-13T13:32Z 125.1K followers, [----] engagements


"And another new kid on the Nature journals block. Welcome Nature Biomedical Engineering https://x.com/natBME/status/707935609684410369 Hello world This is Nature Biomedical Engineering and we are now live. https://t.co/hUm007UFmO https://t.co/psrLpJfj0w https://x.com/natBME/status/707935609684410369 Hello world This is Nature Biomedical Engineering and we are now live. https://t.co/hUm007UFmO https://t.co/psrLpJfj0w"  
[X Link](https://x.com/NatureCellBio/status/707993483915751424)  2016-03-10T18:16Z 124.5K followers, [--] engagements


"A new collection on organoid research is now available Covering recent reviews & perspectives research articles methods & protocols from Nature research journals http://go.nature.com/2LiSPja http://go.nature.com/2LiSPja"  
[X Link](https://x.com/NatureCellBio/status/998759448494538752)  2018-05-22T02:56Z 125.2K followers, [---] engagements

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