[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @JacobPlieth Jacob Plieth Jacob Plieth posts on X about $azn, $gild, $mrna, $iobt the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXXX engagements in the last XX hours. ### Engagements: XXXXXX [#](/creator/twitter::873399943/interactions)  - X Week XXXXXXX +135% - X Month XXXXXXX +38% - X Months XXXXXXXXX +19% - X Year XXXXXXXXX -XX% ### Mentions: XX [#](/creator/twitter::873399943/posts_active)  - X Week XX +60% - X Month XXX +16% - X Months XXX -XXXX% - X Year XXX +8.80% ### Followers: XXXXXX [#](/creator/twitter::873399943/followers)  - X Week XXXXXX +0.18% - X Month XXXXXX +1.10% - X Months XXXXXX +6.50% - X Year XXXXXX +12% ### CreatorRank: XXXXXXX [#](/creator/twitter::873399943/influencer_rank)  ### Social Influence [#](/creator/twitter::873399943/influence) --- **Social category influence** [stocks](/list/stocks) XXXXX% [currencies](/list/currencies) #1898 [finance](/list/finance) XXX% [cryptocurrencies](/list/cryptocurrencies) XXXX% [travel destinations](/list/travel-destinations) XXXX% **Social topic influence** [$azn](/topic/$azn) #4, [$gild](/topic/$gild) #4, [$mrna](/topic/$mrna) #4, [$iobt](/topic/$iobt) #2, [$gmab](/topic/$gmab) #1, [$smmt](/topic/$smmt) #6, [$bntx](/topic/$bntx) #1, [$rhhby](/topic/$rhhby) #7, [$dsnky](/topic/$dsnky) #3, [$lly](/topic/$lly) #7 **Top accounts mentioned or mentioned by** [@apexonco](/creator/undefined) [@bymadeleinea](/creator/undefined) [@notgenentech](/creator/undefined) [@bertrandbio](/creator/undefined) [@persimmonti](/creator/undefined) [@applehelix](/creator/undefined) [@avidresearch](/creator/undefined) [@biotechobserver](/creator/undefined) [@phoenicianstrat](/creator/undefined) [@maverickny](/creator/undefined) [@jeromeleonard5](/creator/undefined) [@tman1138pm](/creator/undefined) [@notthatkindofdr](/creator/undefined) [@evaluatepharma](/creator/undefined) [@drpaulydesantis](/creator/undefined) [@paulpetertak](/creator/undefined) [@cotton67210591](/creator/undefined) [@gatoncarlos](/creator/undefined) [@oncinvestor](/creator/undefined) [@sanctuarybio](/creator/undefined) **Top assets mentioned** [AstraZeneca PLC (AZN)](/topic/$azn) [Gilead Sciences, Inc. (GILD)](/topic/$gild) [Moderna Inc (MRNA)](/topic/$mrna) [Summit Therapeutics Inc. Common Stock (SMMT)](/topic/$smmt) [Eli Lilly and Company (LLY)](/topic/$lly) [Novartis AG (NVS)](/topic/$nvs) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [AbbVie Inc (ABBV)](/topic/$abbv) [Synthetify (SNY)](/topic/$sny) [IDEAYA Biosciences, Inc. Common Stock (IDYA)](/topic/$idya) [GSK plc (GSK)](/topic/$gsk) [One Cash (ONC)](/topic/$onc) [Merus N.V. Common Shares (MRUS)](/topic/$mrus) [Nuvalent, Inc. Class A Common Stock (NUVL)](/topic/$nuvl) [Hundred Million (100M)](/topic/$100m) [Pfizer, Inc. (PFE)](/topic/$pfe) [Incyte Corporation (INCY)](/topic/$incy) [Merck & Co., Inc. (MRK)](/topic/$mrk) [Amgen, Inc. (AMGN)](/topic/$amgn) [Johnson & Johnson (JNJ)](/topic/$jnj) [Arvinas, Inc (ARVN)](/topic/$arvn) [Revolution Medicines, Inc. Common Stock (RVMD)](/topic/$rvmd) [Exelixis Inc (EXEL)](/topic/$exel) ### Top Social Posts [#](/creator/twitter::873399943/posts) --- Top posts by engagements in the last XX hours "#WCLC25 late-breaker & plenary preview via @ApexOnco $SMMT $BMY $BNTX $NUVL $CGEM" [X Link](https://x.com/JacobPlieth/status/1958202262183940590) [@JacobPlieth](/creator/x/JacobPlieth) 2025-08-20T16:19Z 30.9K followers, 17.1K engagements "Plus some other #WCLC25 presentations of note: $LEGN $TIL $NVS $BNTX $CADL" [X Link](https://x.com/JacobPlieth/status/1958616455509155996) [@JacobPlieth](/creator/x/JacobPlieth) 2025-08-21T19:45Z 30.9K followers, 5334 engagements "Remember that $MRNA mRNA-encoded triple T-cell engagers therapy vs BCMA FcRH5 & GPRC5D from #ASH24 It could be mRNA-2808" [X Link](https://x.com/JacobPlieth/status/1958850386745344176) [@JacobPlieth](/creator/x/JacobPlieth) 2025-08-22T11:15Z 30.9K followers, 9210 engagements "In 2023 $NVS paid $LEGN $100m for an anti-DLL3 Car-T. First human data at #WCLC25 show that this still a work in progress. Via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1965744103523811398) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-10T11:48Z 30.9K followers, 5838 engagements "Interesting take on the FcRH5 landscape which seems to be one of $RHHBY's main oncology R&D areas of interest. $MRNA & $LEGN active here" [X Link](https://x.com/JacobPlieth/status/1970769553572454869) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-24T08:37Z 30.9K followers, 4483 engagements "$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24" [X Link](https://x.com/JacobPlieth/status/1866630560355061773) [@JacobPlieth](/creator/x/JacobPlieth) 2024-12-10T23:46Z 30.9K followers, 7600 engagements "So basically $SNY is a pioneer" [X Link](https://x.com/JacobPlieth/status/1976617227169489195) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-10T11:54Z 30.9K followers, 5759 engagements "@jeromeleonard5 @NotthatkindofDr GSK4418959 / IDE275 I was kind of hoping to see FIH data on that at #ESMO25 $GSK $IDYA" [X Link](https://x.com/JacobPlieth/status/1977739462793674925) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T14:13Z 30.9K followers, XXX engagements "Meanwhile here's Skyscraper-03 stage III NSCLC. #tigit combo is no better than Imfinzi but adds tox. No attempt by Rafal Dziaduszko to gloss over how bad these data are #ESMO25 $RHHBY $RCUS $GILD $AZN" [X Link](https://x.com/JacobPlieth/status/1979572793869017474) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T15:38Z 30.9K followers, 2197 engagements "A Bardia confirms: no deaths on datopotamab dxd in Tropion-Breast01 but one ILD gr X was later reanalysed and regraded gr X () $DSNKY $AZN" [X Link](https://x.com/JacobPlieth/status/1716465515919516008) [@JacobPlieth](/creator/x/JacobPlieth) 2023-10-23T14:44Z 30.9K followers, 7204 engagements "New phase X Parp1 inhibitor from Synnovation $MKGAF $GILD $AZN" [X Link](https://x.com/JacobPlieth/status/1752324510047498715) [@JacobPlieth](/creator/x/JacobPlieth) 2024-01-30T13:34Z 30.9K followers, 7669 engagements "Did the FDA tell $IOBT not to file because Keynote-D18 (technically) failed or because it enrolled only XX US patients" [X Link](https://x.com/JacobPlieth/status/1972628599963611422) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-29T11:44Z 30.9K followers, 2694 engagements "So. no $MRNA activity in PD-L1-negatives looks like a win for $IOBT no #ESMO25" [X Link](https://x.com/JacobPlieth/status/1977690767574413571) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T10:59Z 30.9K followers, 10.9K engagements "How did $AZN Potomac readout match $PFE Crest almost number for number Plus a #sadtrombone for Tecentriq in $RHHBY Alban from #ESMO25 yesterday via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1979589056502841635) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T16:43Z 30.9K followers, 2381 engagements "And here's one of the last two men standing in #tigit $RCUS $GILD domvanalimab: first disclosure of OS curves from Edge-Gastric via Yelena Janjigian #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979593749672915069) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T17:01Z 30.9K followers, 2715 engagements "Something tells me $GMAB is about to get eclipsed in folate receptor alpha ADC $LLY $AZN #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979890827871896039) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T12:42Z 30.9K followers, 3615 engagements "First patient now dosed in this study of TUB-040 Tubulis says. Relevant for $ZYME $ADCT $MRSN & MediLink" [X Link](https://x.com/JacobPlieth/status/1803793531779059837) [@JacobPlieth](/creator/x/JacobPlieth) 2024-06-20T14:14Z 30.9K followers, 4385 engagements "More doubts for $SMMT as the Harmoni guessing game continues at #WCLC25. Via @ApexOnco - $BNTX $TIL $BMY" [X Link](https://x.com/JacobPlieth/status/1964771632154812790) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-07T19:23Z 30.9K followers, 11.4K engagements "First $AFMD now $IPHA. what say $ONC & any others still involved in NK-cell engagers" [X Link](https://x.com/JacobPlieth/status/1968302921881370818) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-17T13:16Z 30.9K followers, 5042 engagements "New players in dual-payload ADCs: Lonza Synaffix & Qurient Therapeutics. CDK7 inhibitor" [X Link](https://x.com/JacobPlieth/status/1971118656919830596) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-25T07:44Z 30.9K followers, 2127 engagements "LOL that was quick" [X Link](https://x.com/JacobPlieth/status/1971573097573851440) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-26T13:50Z 30.9K followers, 18.2K engagements "43 patients' worth of data = $8bn of which $5.5bn is being financed through debt $MRUS $GMAB" [X Link](https://x.com/JacobPlieth/status/1972611899255873631) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-29T10:38Z 30.9K followers, 16.6K engagements "Keep them coming big pharma $AZN" [X Link](https://x.com/JacobPlieth/status/1976560869464039797) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-10T08:10Z 30.9K followers, 3195 engagements "Is this a world record Seven days from data toplining to appearance in an #ESMO25 late-breaker $AZN" [X Link](https://x.com/JacobPlieth/status/1977658793690591360) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T08:52Z 30.9K followers, 3612 engagements "$MRNA mRNA-4359 at #ESMO25: ORR XX% (n=9) but no activity at all in PD-L1 non-expressers (n=13) $IOBT" [X Link](https://x.com/JacobPlieth/status/1977669398149427663) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T09:35Z 30.9K followers, 3625 engagements "@avidresearch One caveat is $IOBT is 1st-line whereas $MRNA is checkpoint-refractory but PD-L1-negative comps are probably accurate #ESMO25" [X Link](https://x.com/JacobPlieth/status/1977713645841731736) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T12:30Z 30.9K followers, 1459 engagements "#ESMO25 regular abstracts are now live with first-in-human data being revealed by $LLY $INCY $DSNKY $MRNA $NVS Parabilis & others. Preview via @ApexOnco" [X Link](https://x.com/JacobPlieth/status/1977743598129926308) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-13T14:29Z 30.9K followers, 6401 engagements "V early solid tumour data for Synnovation's Parp1 inhibitor SNV1521 via Pat LoRusso #ESMO25 $AZN $GILD $MKGAF" [X Link](https://x.com/JacobPlieth/status/1979193474214670481) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-17T14:31Z 30.9K followers, 2846 engagements "Fascinating Evercore ISI webinar going on right now about disconnect between value of Sino deal and what $MRK owes Lanova on the PD-1 x VEGF. In summary: XX% of $588m MRK up front and XX% of the $300m tech transfer actually went to Genscript () $LEGN" [X Link](https://x.com/JacobPlieth/status/1946199171704242199) [@JacobPlieth](/creator/x/JacobPlieth) 2025-07-18T13:23Z 30.9K followers, 11.4K engagements "Wow so $AMGN slipped out that bemarituzumab's positive final OS analysis slipped into negative territory at longer follow-up. $ZLAB off X% yesterday -X% premarket today" [X Link](https://x.com/JacobPlieth/status/1963525096221364576) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-04T08:50Z 30.9K followers, 8712 engagements "#ESMO25 Sunday late-breakers: LBA20 - $GILD Ascent-03 "One LBA TBC" LBA21 - unassigned $DSNKY $AZN" [X Link](https://x.com/JacobPlieth/status/1975117046531977337) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-06T08:32Z 30.9K followers, 6993 engagements "How bad was $RHHBY Skyscraper-07 Adding Tigit to PD-L1 + chemo actually shortened survival (prob owing to more AEs). Question now: does Tecentriq + chemo (without tira) have a future in this setting #ESMO25" [X Link](https://x.com/JacobPlieth/status/1978736114006388877) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-16T08:13Z 30.9K followers, 3370 engagements "@raffcolo You saw this detail Gr5 events include X x ILD X x respiratory tract infection X x acute respiratory faillure X x ARDS. Adjuvant setting $DSNKY $AZN #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979573764791652681) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T15:42Z 30.9K followers, XXX engagements "Catching up on some #ASCO25 sessions I came across this on dual-payload ADCs from Patricia LoRusso's clinical science symposium" [X Link](https://x.com/JacobPlieth/status/1930975237924893057) [@JacobPlieth](/creator/x/JacobPlieth) 2025-06-06T13:09Z 30.9K followers, 6710 engagements "First human data for a DNA pol theta inhibitor Artios's ART6043 +/-Lynparza in solid tumours shows X cPR + X uCR. via Tim Yap #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979195138388754918) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-17T14:37Z 30.9K followers, 6941 engagements "Almost the last #tigit standing: $RCUS $GILD domvanalimab flies the flag at #ESMO25. Via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1979801959264866426) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T06:49Z 30.9K followers, 2922 engagements "@ohadhammer Apparently no PFS data on torvuta-S which $AZN had promised in the #ESMO25 abstract" [X Link](https://x.com/JacobPlieth/status/1979878792685666503) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T11:54Z 30.9K followers, XXX engagements "@NotGenentech Unfortunately 120mg/m2 is the only one where $GMAB can claim activity "regardless of FR expression"" [X Link](https://x.com/JacobPlieth/status/1979921653711642743) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T14:44Z 30.9K followers, XXX engagements "$LLY (ex Mablink) anti-FR ADC LY4170156 starts phase X this month $ABBV $GMAB $STRO" [X Link](https://x.com/JacobPlieth/status/1787773937142653204) [@JacobPlieth](/creator/x/JacobPlieth) 2024-05-07T09:18Z 30.9K followers, 3770 engagements "Now $BMY buys Orbital for. $1.5bn Focus seems to be autoimmune but pipeline also includes some oncology work $AZN $ABBV $GILD $SNY $ALPMF" [X Link](https://x.com/JacobPlieth/status/1976608534839357772) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-10T11:19Z 30.9K followers, 14.3K engagements "Napistar1-01 data from Tubulis's TUB-040 coming at an #ESMO25 late-breaker. Meanwhile Tubulis just closed a 308m series C which it claims is the largest series C for a European biotech ever" [X Link](https://x.com/JacobPlieth/status/1978393122263412923) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-15T09:30Z 30.9K followers, 5069 engagements "PD-1 x VEGF news: Shanghai Junshi says it's got FDA approval to start a US ph2/3 trial of JS207 head-to-head vs Opdivo in neoadjuvant NSCLC $SMMT $TIL $BNTX" [X Link](https://x.com/JacobPlieth/status/1978809705532203166) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-16T13:06Z 30.9K followers, 7453 engagements "Novel synthetic lethality approaches from Synnovation Artios & $NVS leave much to prove. Via @ApexOnco at #ESMO25 - $IDYA $RPTX $GSK" [X Link](https://x.com/JacobPlieth/status/1979589418492063916) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T16:44Z 30.9K followers, 2937 engagements "Someone at $AZN might be getting fired for failing to organise a standing ovation for Destiny-Breast05 & XX #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979599455071478251) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-18T17:24Z 30.9K followers, 14.9K engagements "Pretty decent #ESMO25 data for $LLY Mablink-derived FR ADC LY4170156 which is about to go into phase X. XX% ORR in FR 0-24% expressers $GILD $ABBV $AZN" [X Link](https://x.com/JacobPlieth/status/1979811830295040264) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T07:28Z 30.9K followers, 6127 engagements "Meanwhile here's $AZN FR ADC torvutatug samrotecan in first-in-human Fontana study. No clear cut by FR expression #ESMO25 via Ana Oaknin" [X Link](https://x.com/JacobPlieth/status/1979834467411010011) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T08:58Z 30.9K followers, 1509 engagements "So the ILD grading shenanigans continue. Here's another grade X event adjudicated as grade X ILD $DSNKY $AZN #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979850770834141407) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T10:03Z 30.9K followers, 2853 engagements "Does this mean $MRUS $GMAB is screwed" [X Link](https://x.com/JacobPlieth/status/1979919452788380074) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T14:35Z 30.9K followers, 15.4K engagements "Fun facts from the #ESMO25 exhibition hall: $BNTX booth is almost next to $SMMT $IOBT booth is at least twice as big as $MRNA Menarini booth is FREAKIN HUGE" [X Link](https://x.com/JacobPlieth/status/1979935091842236885) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T15:38Z 30.9K followers, 6706 engagements "If you didn't already feel sorry for $IOBT check this out. Presumably paid for before XX Sep #ESMO25" [X Link](https://x.com/JacobPlieth/status/1979980409707307083) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-19T18:38Z 30.9K followers, 3772 engagements "From #ESMO25 yesterday via @ApexOnco - how $LLY sprang a surprise for $AZN in FR. Also key datasets for $GMAB" [X Link](https://x.com/JacobPlieth/status/1980166382575894819) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-20T06:57Z 30.9K followers, 2342 engagements "Hopefully more Harmoni-3 details on today's $SMMT investor call" [X Link](https://x.com/JacobPlieth/status/1980175849904042087) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-20T07:34Z 30.9K followers, 4140 engagements "You already have a small-molecule inhibitor so do you also need a degrader $ONC $BGNE thinks yes for BTK CDK2 & Kras. Via @ApexOnco - $ARVN $GILD $RVMD" [X Link](https://x.com/JacobPlieth/status/1939696857925533733) [@JacobPlieth](/creator/x/JacobPlieth) 2025-06-30T14:45Z 30.9K followers, 4695 engagements "#ESMO25 late-breaker LBA53 but now $IOBT says it can't file on IOB-013 study" [X Link](https://x.com/JacobPlieth/status/1972619740578521276) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-29T11:09Z 30.9K followers, 15.6K engagements "$IOBT (-75% this am) $LPTX $CELC & some other #ESMO25 late breakers via @ApexOnco $EXEL $RHHBY $AZN" [X Link](https://x.com/JacobPlieth/status/1972666229681713650) [@JacobPlieth](/creator/x/JacobPlieth) 2025-09-29T14:14Z 30.9K followers, 3656 engagements "Especially for the science nerds I looked at $AZN's latest attempt at CD8-guided T-cell engagement which seems to be a new take on the Titan planform. Via @ApexOnco -" [X Link](https://x.com/JacobPlieth/status/1973733499749421391) [@JacobPlieth](/creator/x/JacobPlieth) 2025-10-02T12:55Z 30.9K followers, 4557 engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@JacobPlieth Jacob Plieth
Jacob Plieth posts on X about $azn, $gild, $mrna, $iobt the most. They currently have XXXXXX followers and XXX posts still getting attention that total XXXXXX engagements in the last XX hours.
Engagements: XXXXXX #
- X Week XXXXXXX +135%
- X Month XXXXXXX +38%
- X Months XXXXXXXXX +19%
- X Year XXXXXXXXX -XX%
Mentions: XX #
- X Week XX +60%
- X Month XXX +16%
- X Months XXX -XXXX%
- X Year XXX +8.80%
Followers: XXXXXX #
- X Week XXXXXX +0.18%
- X Month XXXXXX +1.10%
- X Months XXXXXX +6.50%
- X Year XXXXXX +12%
CreatorRank: XXXXXXX #
Social Influence #
Social category influence stocks XXXXX% currencies #1898 finance XXX% cryptocurrencies XXXX% travel destinations XXXX%
Social topic influence $azn #4, $gild #4, $mrna #4, $iobt #2, $gmab #1, $smmt #6, $bntx #1, $rhhby #7, $dsnky #3, $lly #7
Top accounts mentioned or mentioned by @apexonco @bymadeleinea @notgenentech @bertrandbio @persimmonti @applehelix @avidresearch @biotechobserver @phoenicianstrat @maverickny @jeromeleonard5 @tman1138pm @notthatkindofdr @evaluatepharma @drpaulydesantis @paulpetertak @cotton67210591 @gatoncarlos @oncinvestor @sanctuarybio
Top assets mentioned AstraZeneca PLC (AZN) Gilead Sciences, Inc. (GILD) Moderna Inc (MRNA) Summit Therapeutics Inc. Common Stock (SMMT) Eli Lilly and Company (LLY) Novartis AG (NVS) Bristol-Myers Squibb Co (BMY) AbbVie Inc (ABBV) Synthetify (SNY) IDEAYA Biosciences, Inc. Common Stock (IDYA) GSK plc (GSK) One Cash (ONC) Merus N.V. Common Shares (MRUS) Nuvalent, Inc. Class A Common Stock (NUVL) Hundred Million (100M) Pfizer, Inc. (PFE) Incyte Corporation (INCY) Merck & Co., Inc. (MRK) Amgen, Inc. (AMGN) Johnson & Johnson (JNJ) Arvinas, Inc (ARVN) Revolution Medicines, Inc. Common Stock (RVMD) Exelixis Inc (EXEL)
Top Social Posts #
Top posts by engagements in the last XX hours
"#WCLC25 late-breaker & plenary preview via @ApexOnco $SMMT $BMY $BNTX $NUVL $CGEM"
X Link @JacobPlieth 2025-08-20T16:19Z 30.9K followers, 17.1K engagements
"Plus some other #WCLC25 presentations of note: $LEGN $TIL $NVS $BNTX $CADL"
X Link @JacobPlieth 2025-08-21T19:45Z 30.9K followers, 5334 engagements
"Remember that $MRNA mRNA-encoded triple T-cell engagers therapy vs BCMA FcRH5 & GPRC5D from #ASH24 It could be mRNA-2808"
X Link @JacobPlieth 2025-08-22T11:15Z 30.9K followers, 9210 engagements
"In 2023 $NVS paid $LEGN $100m for an anti-DLL3 Car-T. First human data at #WCLC25 show that this still a work in progress. Via @ApexOnco -"
X Link @JacobPlieth 2025-09-10T11:48Z 30.9K followers, 5838 engagements
"Interesting take on the FcRH5 landscape which seems to be one of $RHHBY's main oncology R&D areas of interest. $MRNA & $LEGN active here"
X Link @JacobPlieth 2025-09-24T08:37Z 30.9K followers, 4483 engagements
"$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24"
X Link @JacobPlieth 2024-12-10T23:46Z 30.9K followers, 7600 engagements
"So basically $SNY is a pioneer"
X Link @JacobPlieth 2025-10-10T11:54Z 30.9K followers, 5759 engagements
"@jeromeleonard5 @NotthatkindofDr GSK4418959 / IDE275 I was kind of hoping to see FIH data on that at #ESMO25 $GSK $IDYA"
X Link @JacobPlieth 2025-10-13T14:13Z 30.9K followers, XXX engagements
"Meanwhile here's Skyscraper-03 stage III NSCLC. #tigit combo is no better than Imfinzi but adds tox. No attempt by Rafal Dziaduszko to gloss over how bad these data are #ESMO25 $RHHBY $RCUS $GILD $AZN"
X Link @JacobPlieth 2025-10-18T15:38Z 30.9K followers, 2197 engagements
"A Bardia confirms: no deaths on datopotamab dxd in Tropion-Breast01 but one ILD gr X was later reanalysed and regraded gr X () $DSNKY $AZN"
X Link @JacobPlieth 2023-10-23T14:44Z 30.9K followers, 7204 engagements
"New phase X Parp1 inhibitor from Synnovation $MKGAF $GILD $AZN"
X Link @JacobPlieth 2024-01-30T13:34Z 30.9K followers, 7669 engagements
"Did the FDA tell $IOBT not to file because Keynote-D18 (technically) failed or because it enrolled only XX US patients"
X Link @JacobPlieth 2025-09-29T11:44Z 30.9K followers, 2694 engagements
"So. no $MRNA activity in PD-L1-negatives looks like a win for $IOBT no #ESMO25"
X Link @JacobPlieth 2025-10-13T10:59Z 30.9K followers, 10.9K engagements
"How did $AZN Potomac readout match $PFE Crest almost number for number Plus a #sadtrombone for Tecentriq in $RHHBY Alban from #ESMO25 yesterday via @ApexOnco -"
X Link @JacobPlieth 2025-10-18T16:43Z 30.9K followers, 2381 engagements
"And here's one of the last two men standing in #tigit $RCUS $GILD domvanalimab: first disclosure of OS curves from Edge-Gastric via Yelena Janjigian #ESMO25"
X Link @JacobPlieth 2025-10-18T17:01Z 30.9K followers, 2715 engagements
"Something tells me $GMAB is about to get eclipsed in folate receptor alpha ADC $LLY $AZN #ESMO25"
X Link @JacobPlieth 2025-10-19T12:42Z 30.9K followers, 3615 engagements
"First patient now dosed in this study of TUB-040 Tubulis says. Relevant for $ZYME $ADCT $MRSN & MediLink"
X Link @JacobPlieth 2024-06-20T14:14Z 30.9K followers, 4385 engagements
"More doubts for $SMMT as the Harmoni guessing game continues at #WCLC25. Via @ApexOnco - $BNTX $TIL $BMY"
X Link @JacobPlieth 2025-09-07T19:23Z 30.9K followers, 11.4K engagements
"First $AFMD now $IPHA. what say $ONC & any others still involved in NK-cell engagers"
X Link @JacobPlieth 2025-09-17T13:16Z 30.9K followers, 5042 engagements
"New players in dual-payload ADCs: Lonza Synaffix & Qurient Therapeutics. CDK7 inhibitor"
X Link @JacobPlieth 2025-09-25T07:44Z 30.9K followers, 2127 engagements
"LOL that was quick"
X Link @JacobPlieth 2025-09-26T13:50Z 30.9K followers, 18.2K engagements
"43 patients' worth of data = $8bn of which $5.5bn is being financed through debt $MRUS $GMAB"
X Link @JacobPlieth 2025-09-29T10:38Z 30.9K followers, 16.6K engagements
"Keep them coming big pharma $AZN"
X Link @JacobPlieth 2025-10-10T08:10Z 30.9K followers, 3195 engagements
"Is this a world record Seven days from data toplining to appearance in an #ESMO25 late-breaker $AZN"
X Link @JacobPlieth 2025-10-13T08:52Z 30.9K followers, 3612 engagements
"$MRNA mRNA-4359 at #ESMO25: ORR XX% (n=9) but no activity at all in PD-L1 non-expressers (n=13) $IOBT"
X Link @JacobPlieth 2025-10-13T09:35Z 30.9K followers, 3625 engagements
"@avidresearch One caveat is $IOBT is 1st-line whereas $MRNA is checkpoint-refractory but PD-L1-negative comps are probably accurate #ESMO25"
X Link @JacobPlieth 2025-10-13T12:30Z 30.9K followers, 1459 engagements
"#ESMO25 regular abstracts are now live with first-in-human data being revealed by $LLY $INCY $DSNKY $MRNA $NVS Parabilis & others. Preview via @ApexOnco"
X Link @JacobPlieth 2025-10-13T14:29Z 30.9K followers, 6401 engagements
"V early solid tumour data for Synnovation's Parp1 inhibitor SNV1521 via Pat LoRusso #ESMO25 $AZN $GILD $MKGAF"
X Link @JacobPlieth 2025-10-17T14:31Z 30.9K followers, 2846 engagements
"Fascinating Evercore ISI webinar going on right now about disconnect between value of Sino deal and what $MRK owes Lanova on the PD-1 x VEGF. In summary: XX% of $588m MRK up front and XX% of the $300m tech transfer actually went to Genscript () $LEGN"
X Link @JacobPlieth 2025-07-18T13:23Z 30.9K followers, 11.4K engagements
"Wow so $AMGN slipped out that bemarituzumab's positive final OS analysis slipped into negative territory at longer follow-up. $ZLAB off X% yesterday -X% premarket today"
X Link @JacobPlieth 2025-09-04T08:50Z 30.9K followers, 8712 engagements
"#ESMO25 Sunday late-breakers: LBA20 - $GILD Ascent-03 "One LBA TBC" LBA21 - unassigned $DSNKY $AZN"
X Link @JacobPlieth 2025-10-06T08:32Z 30.9K followers, 6993 engagements
"How bad was $RHHBY Skyscraper-07 Adding Tigit to PD-L1 + chemo actually shortened survival (prob owing to more AEs). Question now: does Tecentriq + chemo (without tira) have a future in this setting #ESMO25"
X Link @JacobPlieth 2025-10-16T08:13Z 30.9K followers, 3370 engagements
"@raffcolo You saw this detail Gr5 events include X x ILD X x respiratory tract infection X x acute respiratory faillure X x ARDS. Adjuvant setting $DSNKY $AZN #ESMO25"
X Link @JacobPlieth 2025-10-18T15:42Z 30.9K followers, XXX engagements
"Catching up on some #ASCO25 sessions I came across this on dual-payload ADCs from Patricia LoRusso's clinical science symposium"
X Link @JacobPlieth 2025-06-06T13:09Z 30.9K followers, 6710 engagements
"First human data for a DNA pol theta inhibitor Artios's ART6043 +/-Lynparza in solid tumours shows X cPR + X uCR. via Tim Yap #ESMO25"
X Link @JacobPlieth 2025-10-17T14:37Z 30.9K followers, 6941 engagements
"Almost the last #tigit standing: $RCUS $GILD domvanalimab flies the flag at #ESMO25. Via @ApexOnco -"
X Link @JacobPlieth 2025-10-19T06:49Z 30.9K followers, 2922 engagements
"@ohadhammer Apparently no PFS data on torvuta-S which $AZN had promised in the #ESMO25 abstract"
X Link @JacobPlieth 2025-10-19T11:54Z 30.9K followers, XXX engagements
"@NotGenentech Unfortunately 120mg/m2 is the only one where $GMAB can claim activity "regardless of FR expression""
X Link @JacobPlieth 2025-10-19T14:44Z 30.9K followers, XXX engagements
"$LLY (ex Mablink) anti-FR ADC LY4170156 starts phase X this month $ABBV $GMAB $STRO"
X Link @JacobPlieth 2024-05-07T09:18Z 30.9K followers, 3770 engagements
"Now $BMY buys Orbital for. $1.5bn Focus seems to be autoimmune but pipeline also includes some oncology work $AZN $ABBV $GILD $SNY $ALPMF"
X Link @JacobPlieth 2025-10-10T11:19Z 30.9K followers, 14.3K engagements
"Napistar1-01 data from Tubulis's TUB-040 coming at an #ESMO25 late-breaker. Meanwhile Tubulis just closed a 308m series C which it claims is the largest series C for a European biotech ever"
X Link @JacobPlieth 2025-10-15T09:30Z 30.9K followers, 5069 engagements
"PD-1 x VEGF news: Shanghai Junshi says it's got FDA approval to start a US ph2/3 trial of JS207 head-to-head vs Opdivo in neoadjuvant NSCLC $SMMT $TIL $BNTX"
X Link @JacobPlieth 2025-10-16T13:06Z 30.9K followers, 7453 engagements
"Novel synthetic lethality approaches from Synnovation Artios & $NVS leave much to prove. Via @ApexOnco at #ESMO25 - $IDYA $RPTX $GSK"
X Link @JacobPlieth 2025-10-18T16:44Z 30.9K followers, 2937 engagements
"Someone at $AZN might be getting fired for failing to organise a standing ovation for Destiny-Breast05 & XX #ESMO25"
X Link @JacobPlieth 2025-10-18T17:24Z 30.9K followers, 14.9K engagements
"Pretty decent #ESMO25 data for $LLY Mablink-derived FR ADC LY4170156 which is about to go into phase X. XX% ORR in FR 0-24% expressers $GILD $ABBV $AZN"
X Link @JacobPlieth 2025-10-19T07:28Z 30.9K followers, 6127 engagements
"Meanwhile here's $AZN FR ADC torvutatug samrotecan in first-in-human Fontana study. No clear cut by FR expression #ESMO25 via Ana Oaknin"
X Link @JacobPlieth 2025-10-19T08:58Z 30.9K followers, 1509 engagements
"So the ILD grading shenanigans continue. Here's another grade X event adjudicated as grade X ILD $DSNKY $AZN #ESMO25"
X Link @JacobPlieth 2025-10-19T10:03Z 30.9K followers, 2853 engagements
"Does this mean $MRUS $GMAB is screwed"
X Link @JacobPlieth 2025-10-19T14:35Z 30.9K followers, 15.4K engagements
"Fun facts from the #ESMO25 exhibition hall: $BNTX booth is almost next to $SMMT $IOBT booth is at least twice as big as $MRNA Menarini booth is FREAKIN HUGE"
X Link @JacobPlieth 2025-10-19T15:38Z 30.9K followers, 6706 engagements
"If you didn't already feel sorry for $IOBT check this out. Presumably paid for before XX Sep #ESMO25"
X Link @JacobPlieth 2025-10-19T18:38Z 30.9K followers, 3772 engagements
"From #ESMO25 yesterday via @ApexOnco - how $LLY sprang a surprise for $AZN in FR. Also key datasets for $GMAB"
X Link @JacobPlieth 2025-10-20T06:57Z 30.9K followers, 2342 engagements
"Hopefully more Harmoni-3 details on today's $SMMT investor call"
X Link @JacobPlieth 2025-10-20T07:34Z 30.9K followers, 4140 engagements
"You already have a small-molecule inhibitor so do you also need a degrader $ONC $BGNE thinks yes for BTK CDK2 & Kras. Via @ApexOnco - $ARVN $GILD $RVMD"
X Link @JacobPlieth 2025-06-30T14:45Z 30.9K followers, 4695 engagements
"#ESMO25 late-breaker LBA53 but now $IOBT says it can't file on IOB-013 study"
X Link @JacobPlieth 2025-09-29T11:09Z 30.9K followers, 15.6K engagements
"$IOBT (-75% this am) $LPTX $CELC & some other #ESMO25 late breakers via @ApexOnco $EXEL $RHHBY $AZN"
X Link @JacobPlieth 2025-09-29T14:14Z 30.9K followers, 3656 engagements
"Especially for the science nerds I looked at $AZN's latest attempt at CD8-guided T-cell engagement which seems to be a new take on the Titan planform. Via @ApexOnco -"
X Link @JacobPlieth 2025-10-02T12:55Z 30.9K followers, 4557 engagements