[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.] #  @Dr_Oncologista Aya Mohamed | MSc, MD 🎗 Aya Mohamed | MSc, MD 🎗 posts on X about breast cancer, iv, mothers, cohort the most. They currently have XXXXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours. ### Engagements: XXXXX [#](/creator/twitter::1157309656123023361/interactions)  - X Week XXXXXX +143,488% - X Year XXXXXX +96% ### Mentions: XX [#](/creator/twitter::1157309656123023361/posts_active)  ### Followers: XXXXX [#](/creator/twitter::1157309656123023361/followers)  - X Week XXXXX +4.10% - X Months XXXXX +25% - X Year XXXXX +40% ### CreatorRank: XXXXXXXXX [#](/creator/twitter::1157309656123023361/influencer_rank)  ### Social Influence [#](/creator/twitter::1157309656123023361/influence) --- **Social topic influence** [breast cancer](/topic/breast-cancer), [iv](/topic/iv), [mothers](/topic/mothers), [cohort](/topic/cohort), [pam](/topic/pam), [efs](/topic/efs), [promising](/topic/promising), [aya](/topic/aya) #127, [os](/topic/os) #141 ### Top Social Posts [#](/creator/twitter::1157309656123023361/posts) --- Top posts by engagements in the last XX hours "PLANET: Low-dose pembrolizumab in neoadjuvant therapy for triple-negative #BreastCancer Showing that conducting quality clinical research developed and funded by government entities shouldn't be a first-world privilege. @OncoAlert #ESMO25 #bcsm" [X Link](https://x.com/Dr_Oncologista/status/1979357573347496210) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T01:23Z 1236 followers, XXX engagements "In a bold design researchers from New Delhi proposed neoadjuvant treatment of patients with TNBC with Pembrolizumab XX mg IV every X weeks And evaluate what would happen in terms of PCR But before the results some points of divergence with the KN-522:" [X Link](https://x.com/Dr_Oncologista/status/1979357577134960931) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T01:23Z 1234 followers, XX engagements "Patients under XX yrs of age with HR+ breast cancer (HER2- or HER2+) stages I-III who wish to become pregnant were enrolled in a single-arm trial to discontinue adjuvant endocrine therapy for up to X yrs become mothers and then resume treatment until completion (5-10 yrs)" [X Link](https://x.com/Dr_Oncologista/status/1979361565444051376) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T01:39Z 1234 followers, XX engagements "With the control done historically with the women of SOFT-TEXT (for ethical reasons it could not be a randomized study)" [X Link](https://x.com/Dr_Oncologista/status/1979361571056054572) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T01:39Z 1234 followers, XX engagements "VIKTORIA-1 Study Targeting HR+/HER2- PIK3CA wild-type metastatic/recurrent #breastcancer (after CDK4/6 inhibitor) Gedatolisib + Fulvestrant Palbociclib vs Fulvestrant alone PFS: @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979470795429531976) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T08:53Z 1254 followers, 1437 engagements "VIKTORIA-1 study evaluating Gedatosib a PAM inhibitor of the PI3K-AKT-mTOR pathway in association with FULV +- Palbociclib Positive study with PFS gain in this PIK3CAwt cohort will we still need to test @OncoAlert #ESMO25 @myESMO" [X Link](https://x.com/Dr_Oncologista/status/1979522350325629040) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T12:18Z 1254 followers, XXX engagements "DESTINY-Breast11 trial reported favorable EFS results with a XXXX% improvement in pCR when T-DXd was used as neoadjuvant chemotherapy followed by THP. #ESMO25 @OncoAlert" [X Link](https://x.com/Dr_Oncologista/status/1979570430680641921) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T15:29Z 1254 followers, XXX engagements "TROPION-Breast02 Another anti-TROP2 now Datopotamab Deruxtecan also in this same 1L scenario in patients not eligible for immunotherapy No crossover was allowed (Dato-DXd has no OS in subsequent lines)and about XX% of population with relapse interval 6m @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979861068509024540) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T10:43Z 1253 followers, XXX engagements "DESTINY-Breast05 Adjuvant study in residual disease with TDXd after neoadjuvance in HER2+ disease Patients at highest risk in the inclusion criteria control arm along the lines of the KATHERINE study @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979601106381553800) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T17:30Z 1254 followers, 1188 engagements "Another new standard of care for triple-negative first-line cancers A phase III trial comparing Dato-DXd vs. chemotherapy in patients with untreated metastatic/recurrent TNBC who were ineligible for ICI. @OncoAlert #ESMO25 #bcsm" [X Link](https://x.com/Dr_Oncologista/status/1979850310568018340) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T10:01Z 1252 followers, 2543 engagements "PSMAddition Scott Tagawa presents PIII trial of Lu-PSMa -XXX + ADT + ARPI in PSMA positive HSPC Discrete gain in SLPr immature SG @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979946057984291230) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T16:21Z 1252 followers, XXX engagements "🔹Innovative molecule with demonstrated efficacy control with XX Chinese that performed the same as KN407 still without OS data. 🔹 The global HARMONI-3 study of 1L NSCLC independent of histology is awaited for confirmation and validation of the data. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980161238421414259) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T06:36Z 1254 followers, XXX engagements "PSMAddition 1st line castration-sensitive metastatic prostate cancer Androgen Deprivation Therapy Antiandrogen Therapy +/- Lutecio177-PSMA617 Significant benefit for radiological progression-free survival ➡ Immature Overall Survival @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980167548470714586) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T07:01Z 1254 followers, XXX engagements "Low TGI oral session CHECKMATE 8HW data updated Result only for 1st line IPI + NIVO with relevant numerical difference in SLP in relative to NIVO Global Survival (Here in all tto lines ) Still Immature Breakwater analysis according to CTDNA dynamics @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980228980843352536) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T11:05Z 1252 followers, 1664 engagements "the beautiful data from POSITIVE now mature at X yrs Dr. Fedro Peccatori and this group of young #BreastCancer experts are conducting one of the most exciting studies of the decade. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979361561807643080) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T01:39Z 1244 followers, XXX engagements "evERA-BC trial; Giredestrant (oral SERD) + everolimus vs SOC ET + everolimus in ER+/HER2 advanced breast cancer previously treated with CDK4/6i ESR1m population: median PFS XXXX vs XXXX mo HR XXXX (p0.0001) @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979465392725856673) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T08:31Z 1237 followers, XXX engagements "evERA very interesting study competitive with the main combination in this scenario at the moment: Imlu + Abema (EMBER-3) First phase X to evaluate the oral SERD + mTOR inhibitor combination In a population of post-PD patients iCDK4/6 @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979549214645375421) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T14:04Z 1245 followers, XXX engagements "Establishing a new standard of care DESTINY-Breast05 A phase III trial comparing T-DXd (trastuzumab deruxtecan) vs. T-DM1 in high-risk HER2-positive early breast cancer with residual invasive disease (non-pCR) after neoadjuvant chemotherapy. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979569481992044986) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T15:25Z 1245 followers, XXX engagements "Results after CDK4/6 inhibitor treatment including the VIKTORIA-1 and eveERA-BC trials #ESMO25 @OncoAlert" [X Link](https://x.com/Dr_Oncologista/status/1979471281155097086) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T08:55Z 1247 followers, XXX engagements "OptiTROP-Breast02 Chinese study with new anti-TROP2 ADC after depleting HT in RH+ patients. Sacituzumab tirumotecan Results from the randomized multi-center phase Ill #ESMO25 @OncoAlert" [X Link](https://x.com/Dr_Oncologista/status/1979520169710915622) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T12:09Z 1247 followers, XXX engagements "evERA very interesting study competitive with the main combination in this scenario at the moment: Imlu + Abema (EMBER-3) First phase X to evaluate the oral SERD + mTOR inhibitor combination In a population of post-PD patients iCDK4/6" [X Link](https://x.com/Dr_Oncologista/status/1979548277201854602) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T14:01Z 1247 followers, XXX engagements "CARES-009 phase X study of perioperative camrelizumab and rivoceranib for HCC And data on perioperative immunotherapy and antiangiogenic therapy in HCC X cycles of preoperative Camrelizumab and Rivoceranib @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979867917354488034) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T11:11Z 1246 followers, XXX engagements "Positive study for PFS with gain compared to QT-10 regardless of the PD-L1 status assessed OS still immature safety data without significant increase in AE including bleeding risk" [X Link](https://x.com/Dr_Oncologista/status/1980160993973203367) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T06:35Z 1247 followers, XX engagements "FOG001 a beta-catenin TCF interaction inhibitor is effective in treating desmoid tumors even in patients previously treated with gamma-secretase inhibitors. It's showing promise. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979215012984987985) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-17T15:56Z 1252 followers, XXX engagements "DeLLphi-303: Phase 1b study evaluating tarlatamab combined with CT+10 in extensive small cell lung disease 🔹Interesting SG result in 1st @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979491386207400432) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T10:14Z 1252 followers, XXX engagements "A new standard of care for first-line triple-negative chemotherapy ASENT-03 Study: A Phase III trial comparing sacituzumab govitecan (SG)** with chemotherapy in patients with untreated metastatic TNBC who are ineligible for PD-L1 inhibitors @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979851597992935603) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T10:06Z 1254 followers, XXX engagements "Richard Finn presents the results of phase X IMbrave152/SkYSCRAPER-14 study at @myESMO Anti-TIGIT tiragolumab does not add benefit to atezolizumab-bevacizumab for patients with advanced HCC @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979869336631390382) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T11:16Z 1252 followers, XXX engagements "OptiTROP-Lung04 Sacituzumab Tirumotecan an anti-TROP2 ADC in 2L in EGFRmut NSCLC after PD to TKI Without TROP2 biomarker analysis XX% received 3rd Generation TKI Positive study for PFS and OS with median not reached with XX% risk reduction @OncoAlert #ESMO25 #lcsm" [X Link](https://x.com/Dr_Oncologista/status/1980163483590132197) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T06:45Z 1252 followers, XXX engagements "Advanced Bladder Cancer 1st line and HER2 expressed 1+ 2+ or 3+ Disitamabe Vedotin + Toripalimabe VSplatinum-based QT Significant benefit in SLP Some HER2 expression is present in up to XX% of cases Enriched in high urothelial treatment @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980171181312586066) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T07:16Z 1252 followers, XXX engagements "Encouraging Results for VT3989 in Advanced Solid Tumors Phase 1/2 study (NCT04665206) of VT3989 (a YAP/TEAD inhibitor) shows promising data: Strong Efficacy: Broad tumor shrinkage observed in mesothelioma patients at the optimized dose. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980186972741398900) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T08:18Z 1252 followers, XXX engagements "The QT interval appears to be important for improving ctDNA clearance and reducing the emergence of known resistant variants. The question is: Is this situation sustainable and does it relate to as-yet-unknown variants ZANZALITINIBE =TKI MULTIKINASE ATEZOLIZUMABE= ANTI PD-L1" [X Link](https://x.com/Dr_Oncologista/status/1980228984341463056) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T11:05Z 1252 followers, XX engagements "Phase III study of adjuvant ensartinib versus placebo for surgically resected ALK+ mutant non-small cell lung cancer (NSCLC). Ensartinib demonstrated a significant and statistically significant clinical and progression-free survival (DFS) benefit @OncoAlert #ESMO25 @Lung_Cancers" [X Link](https://x.com/Dr_Oncologista/status/1980265281919300011) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T13:30Z 1254 followers, XXX engagements "MonarchE trial - X year abemaciclib in early #breastcancer - shows a survival benefit (1.8% difference at X yrs) I was glad to see granularity in post-recurrence therapy data which are key in interpretating any survival benefit #ESMO25 @OncoAlert @myESMO #bcsm" [X Link](https://x.com/Dr_Oncologista/status/1979213560199753819) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-17T15:50Z 1246 followers, XXX engagements "The effects of HDAC inhibitors and PD-1 inhibitors. In liposarcoma the response rate was XX% for well-differentiated and dedifferentiated tumors. It is difficult to explain biologically why the combination is so effective @OncoAlert @myESMO #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979214516551311649) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-17T15:54Z 1246 followers, XXX engagements "Study evaluating multidisciplinary discussion (MDT) followed by induction chemotherapy + IO X XX and new MDT Most patients even those borderline for resection were operated on after QT + XX induction @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979494082838688098) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T10:25Z 1246 followers, XXX engagements "Presidential EVP from KN905 in MIBC at @myESMO with incredibly strong data. PathCR of XX% EFS and OS positive a game changing study continuation of treatment with EV in those with pCR Is cisplatin candidacy still relevant for MIBC @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979603650176766012) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-18T17:41Z 1247 followers, XXX engagements "DESTINY-Breast09 Updated PFS data in subgroup analysis of TDXd in 1L in HER2+ First presentation of efficacy data at this yrs ASCO CHAIRS RUPERT BARTSCH SEOCK @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979847237703520601) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T09:48Z 1247 followers, XXX engagements "ASENT-03 Study Sacituzumab Govitecan anti-TROP2 in 1L in TNBC not a candidate for immunotherapy It is worth noting that patients with a recurrence interval 6m were not included but the crossover allowed is beneficial since Saci-Gov has gained OS in 2L. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1979854524228813230) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-19T10:17Z 1247 followers, XXX engagements "HARMONI-6 Study of Ivonescimab +QT versus 10+QT 1L in patients with PD-L1-independent squamous NSCLC in a Chinese population 🔹Independent of PD-L1 in Chinese population @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980160979435450779) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-20T06:35Z 1247 followers, XXX engagements "future treatment of this patient population relies on combinations of novel SERDs/SERMs with other targeted agents particularly those inhibiting the PI3K/AKT/mTOR signaling pathway to successfully bypass the conventional 6-month PFS threshold. @OncoAlert #ESMO25" [X Link](https://x.com/Dr_Oncologista/status/1980566824812167215) [@Dr_Oncologista](/creator/x/Dr_Oncologista) 2025-10-21T09:28Z 1254 followers, 1275 engagements
[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
Aya Mohamed | MSc, MD 🎗 posts on X about breast cancer, iv, mothers, cohort the most. They currently have XXXXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours.
Social topic influence breast cancer, iv, mothers, cohort, pam, efs, promising, aya #127, os #141
Top posts by engagements in the last XX hours
"PLANET: Low-dose pembrolizumab in neoadjuvant therapy for triple-negative #BreastCancer Showing that conducting quality clinical research developed and funded by government entities shouldn't be a first-world privilege. @OncoAlert #ESMO25 #bcsm"
X Link @Dr_Oncologista 2025-10-18T01:23Z 1236 followers, XXX engagements
"In a bold design researchers from New Delhi proposed neoadjuvant treatment of patients with TNBC with Pembrolizumab XX mg IV every X weeks And evaluate what would happen in terms of PCR But before the results some points of divergence with the KN-522:"
X Link @Dr_Oncologista 2025-10-18T01:23Z 1234 followers, XX engagements
"Patients under XX yrs of age with HR+ breast cancer (HER2- or HER2+) stages I-III who wish to become pregnant were enrolled in a single-arm trial to discontinue adjuvant endocrine therapy for up to X yrs become mothers and then resume treatment until completion (5-10 yrs)"
X Link @Dr_Oncologista 2025-10-18T01:39Z 1234 followers, XX engagements
"With the control done historically with the women of SOFT-TEXT (for ethical reasons it could not be a randomized study)"
X Link @Dr_Oncologista 2025-10-18T01:39Z 1234 followers, XX engagements
"VIKTORIA-1 Study Targeting HR+/HER2- PIK3CA wild-type metastatic/recurrent #breastcancer (after CDK4/6 inhibitor) Gedatolisib + Fulvestrant Palbociclib vs Fulvestrant alone PFS: @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T08:53Z 1254 followers, 1437 engagements
"VIKTORIA-1 study evaluating Gedatosib a PAM inhibitor of the PI3K-AKT-mTOR pathway in association with FULV +- Palbociclib Positive study with PFS gain in this PIK3CAwt cohort will we still need to test @OncoAlert #ESMO25 @myESMO"
X Link @Dr_Oncologista 2025-10-18T12:18Z 1254 followers, XXX engagements
"DESTINY-Breast11 trial reported favorable EFS results with a XXXX% improvement in pCR when T-DXd was used as neoadjuvant chemotherapy followed by THP. #ESMO25 @OncoAlert"
X Link @Dr_Oncologista 2025-10-18T15:29Z 1254 followers, XXX engagements
"TROPION-Breast02 Another anti-TROP2 now Datopotamab Deruxtecan also in this same 1L scenario in patients not eligible for immunotherapy No crossover was allowed (Dato-DXd has no OS in subsequent lines)and about XX% of population with relapse interval 6m @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T10:43Z 1253 followers, XXX engagements
"DESTINY-Breast05 Adjuvant study in residual disease with TDXd after neoadjuvance in HER2+ disease Patients at highest risk in the inclusion criteria control arm along the lines of the KATHERINE study @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T17:30Z 1254 followers, 1188 engagements
"Another new standard of care for triple-negative first-line cancers A phase III trial comparing Dato-DXd vs. chemotherapy in patients with untreated metastatic/recurrent TNBC who were ineligible for ICI. @OncoAlert #ESMO25 #bcsm"
X Link @Dr_Oncologista 2025-10-19T10:01Z 1252 followers, 2543 engagements
"PSMAddition Scott Tagawa presents PIII trial of Lu-PSMa -XXX + ADT + ARPI in PSMA positive HSPC Discrete gain in SLPr immature SG @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T16:21Z 1252 followers, XXX engagements
"🔹Innovative molecule with demonstrated efficacy control with XX Chinese that performed the same as KN407 still without OS data. 🔹 The global HARMONI-3 study of 1L NSCLC independent of histology is awaited for confirmation and validation of the data. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-20T06:36Z 1254 followers, XXX engagements
"PSMAddition 1st line castration-sensitive metastatic prostate cancer Androgen Deprivation Therapy Antiandrogen Therapy +/- Lutecio177-PSMA617 Significant benefit for radiological progression-free survival ➡ Immature Overall Survival @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-20T07:01Z 1254 followers, XXX engagements
"Low TGI oral session CHECKMATE 8HW data updated Result only for 1st line IPI + NIVO with relevant numerical difference in SLP in relative to NIVO Global Survival (Here in all tto lines ) Still Immature Breakwater analysis according to CTDNA dynamics @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-20T11:05Z 1252 followers, 1664 engagements
"the beautiful data from POSITIVE now mature at X yrs Dr. Fedro Peccatori and this group of young #BreastCancer experts are conducting one of the most exciting studies of the decade. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T01:39Z 1244 followers, XXX engagements
"evERA-BC trial; Giredestrant (oral SERD) + everolimus vs SOC ET + everolimus in ER+/HER2 advanced breast cancer previously treated with CDK4/6i ESR1m population: median PFS XXXX vs XXXX mo HR XXXX (p0.0001) @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T08:31Z 1237 followers, XXX engagements
"evERA very interesting study competitive with the main combination in this scenario at the moment: Imlu + Abema (EMBER-3) First phase X to evaluate the oral SERD + mTOR inhibitor combination In a population of post-PD patients iCDK4/6 @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T14:04Z 1245 followers, XXX engagements
"Establishing a new standard of care DESTINY-Breast05 A phase III trial comparing T-DXd (trastuzumab deruxtecan) vs. T-DM1 in high-risk HER2-positive early breast cancer with residual invasive disease (non-pCR) after neoadjuvant chemotherapy. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T15:25Z 1245 followers, XXX engagements
"Results after CDK4/6 inhibitor treatment including the VIKTORIA-1 and eveERA-BC trials #ESMO25 @OncoAlert"
X Link @Dr_Oncologista 2025-10-18T08:55Z 1247 followers, XXX engagements
"OptiTROP-Breast02 Chinese study with new anti-TROP2 ADC after depleting HT in RH+ patients. Sacituzumab tirumotecan Results from the randomized multi-center phase Ill #ESMO25 @OncoAlert"
X Link @Dr_Oncologista 2025-10-18T12:09Z 1247 followers, XXX engagements
"evERA very interesting study competitive with the main combination in this scenario at the moment: Imlu + Abema (EMBER-3) First phase X to evaluate the oral SERD + mTOR inhibitor combination In a population of post-PD patients iCDK4/6"
X Link @Dr_Oncologista 2025-10-18T14:01Z 1247 followers, XXX engagements
"CARES-009 phase X study of perioperative camrelizumab and rivoceranib for HCC And data on perioperative immunotherapy and antiangiogenic therapy in HCC X cycles of preoperative Camrelizumab and Rivoceranib @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T11:11Z 1246 followers, XXX engagements
"Positive study for PFS with gain compared to QT-10 regardless of the PD-L1 status assessed OS still immature safety data without significant increase in AE including bleeding risk"
X Link @Dr_Oncologista 2025-10-20T06:35Z 1247 followers, XX engagements
"FOG001 a beta-catenin TCF interaction inhibitor is effective in treating desmoid tumors even in patients previously treated with gamma-secretase inhibitors. It's showing promise. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-17T15:56Z 1252 followers, XXX engagements
"DeLLphi-303: Phase 1b study evaluating tarlatamab combined with CT+10 in extensive small cell lung disease 🔹Interesting SG result in 1st @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T10:14Z 1252 followers, XXX engagements
"A new standard of care for first-line triple-negative chemotherapy ASENT-03 Study: A Phase III trial comparing sacituzumab govitecan (SG)** with chemotherapy in patients with untreated metastatic TNBC who are ineligible for PD-L1 inhibitors @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T10:06Z 1254 followers, XXX engagements
"Richard Finn presents the results of phase X IMbrave152/SkYSCRAPER-14 study at @myESMO Anti-TIGIT tiragolumab does not add benefit to atezolizumab-bevacizumab for patients with advanced HCC @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T11:16Z 1252 followers, XXX engagements
"OptiTROP-Lung04 Sacituzumab Tirumotecan an anti-TROP2 ADC in 2L in EGFRmut NSCLC after PD to TKI Without TROP2 biomarker analysis XX% received 3rd Generation TKI Positive study for PFS and OS with median not reached with XX% risk reduction @OncoAlert #ESMO25 #lcsm"
X Link @Dr_Oncologista 2025-10-20T06:45Z 1252 followers, XXX engagements
"Advanced Bladder Cancer 1st line and HER2 expressed 1+ 2+ or 3+ Disitamabe Vedotin + Toripalimabe VSplatinum-based QT Significant benefit in SLP Some HER2 expression is present in up to XX% of cases Enriched in high urothelial treatment @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-20T07:16Z 1252 followers, XXX engagements
"Encouraging Results for VT3989 in Advanced Solid Tumors Phase 1/2 study (NCT04665206) of VT3989 (a YAP/TEAD inhibitor) shows promising data: Strong Efficacy: Broad tumor shrinkage observed in mesothelioma patients at the optimized dose. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-20T08:18Z 1252 followers, XXX engagements
"The QT interval appears to be important for improving ctDNA clearance and reducing the emergence of known resistant variants. The question is: Is this situation sustainable and does it relate to as-yet-unknown variants ZANZALITINIBE =TKI MULTIKINASE ATEZOLIZUMABE= ANTI PD-L1"
X Link @Dr_Oncologista 2025-10-20T11:05Z 1252 followers, XX engagements
"Phase III study of adjuvant ensartinib versus placebo for surgically resected ALK+ mutant non-small cell lung cancer (NSCLC). Ensartinib demonstrated a significant and statistically significant clinical and progression-free survival (DFS) benefit @OncoAlert #ESMO25 @Lung_Cancers"
X Link @Dr_Oncologista 2025-10-20T13:30Z 1254 followers, XXX engagements
"MonarchE trial - X year abemaciclib in early #breastcancer - shows a survival benefit (1.8% difference at X yrs) I was glad to see granularity in post-recurrence therapy data which are key in interpretating any survival benefit #ESMO25 @OncoAlert @myESMO #bcsm"
X Link @Dr_Oncologista 2025-10-17T15:50Z 1246 followers, XXX engagements
"The effects of HDAC inhibitors and PD-1 inhibitors. In liposarcoma the response rate was XX% for well-differentiated and dedifferentiated tumors. It is difficult to explain biologically why the combination is so effective @OncoAlert @myESMO #ESMO25"
X Link @Dr_Oncologista 2025-10-17T15:54Z 1246 followers, XXX engagements
"Study evaluating multidisciplinary discussion (MDT) followed by induction chemotherapy + IO X XX and new MDT Most patients even those borderline for resection were operated on after QT + XX induction @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T10:25Z 1246 followers, XXX engagements
"Presidential EVP from KN905 in MIBC at @myESMO with incredibly strong data. PathCR of XX% EFS and OS positive a game changing study continuation of treatment with EV in those with pCR Is cisplatin candidacy still relevant for MIBC @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-18T17:41Z 1247 followers, XXX engagements
"DESTINY-Breast09 Updated PFS data in subgroup analysis of TDXd in 1L in HER2+ First presentation of efficacy data at this yrs ASCO CHAIRS RUPERT BARTSCH SEOCK @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T09:48Z 1247 followers, XXX engagements
"ASENT-03 Study Sacituzumab Govitecan anti-TROP2 in 1L in TNBC not a candidate for immunotherapy It is worth noting that patients with a recurrence interval 6m were not included but the crossover allowed is beneficial since Saci-Gov has gained OS in 2L. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-19T10:17Z 1247 followers, XXX engagements
"HARMONI-6 Study of Ivonescimab +QT versus 10+QT 1L in patients with PD-L1-independent squamous NSCLC in a Chinese population 🔹Independent of PD-L1 in Chinese population @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-20T06:35Z 1247 followers, XXX engagements
"future treatment of this patient population relies on combinations of novel SERDs/SERMs with other targeted agents particularly those inhibiting the PI3K/AKT/mTOR signaling pathway to successfully bypass the conventional 6-month PFS threshold. @OncoAlert #ESMO25"
X Link @Dr_Oncologista 2025-10-21T09:28Z 1254 followers, 1275 engagements
/creator/twitter::Dr_Oncologista