#  @DoctorDueDiligence DoctorDueDiligence DoctorDueDiligence posts on Reddit about $kpti, linkedin, ceo, $abbv the most. They currently have [-----] followers and [---] posts still getting attention that total [---] engagements in the last [--] hours. ### Engagements: [---] [#](/creator/reddit::t2_bohskbh8/interactions)  - [--] Week [-----] -6.90% - [--] Month [-----] +436% - [--] Months [-----] +200% - [--] Year [------] +22% ### Mentions: [--] [#](/creator/reddit::t2_bohskbh8/posts_active)  - [--] Week [--] -15% - [--] Month [--] -46% - [--] Months [--] -46% - [--] Year [---] +4.80% ### Followers: [-----] [#](/creator/reddit::t2_bohskbh8/followers)  - [--] Months [-----] +0.90% - [--] Year [-----] +6.50% ### CreatorRank: [---------] [#](/creator/reddit::t2_bohskbh8/influencer_rank)  ### Social Influence **Social category influence** [finance](/list/finance) [stocks](/list/stocks) [technology brands](/list/technology-brands) [social networks](/list/social-networks) [cryptocurrencies](/list/cryptocurrencies) [travel destinations](/list/travel-destinations) [currencies](/list/currencies) [exchanges](/list/exchanges) [countries](/list/countries) [automotive brands](/list/automotive-brands) **Social topic influence** [$kpti](/topic/$kpti) #13, [linkedin](/topic/linkedin), [ceo](/topic/ceo), [$abbv](/topic/$abbv), [debt](/topic/debt), [investment](/topic/investment), [$fro](/topic/$fro), [$sage](/topic/$sage), [$crtx](/topic/$crtx) #1, [$mor](/topic/$mor) **Top accounts mentioned or mentioned by** [@duedoctor](/creator/undefined) **Top assets mentioned** [AbbVie Inc (ABBV)](/topic/$abbv) [Frontline Ltd. (FRO)](/topic/$fro) [Sage Therapeutics, Inc (SAGE)](/topic/$sage) [Bluefin (BLUE)](/topic/$blue) [Pfizer, Inc. (PFE)](/topic/$pfe) [Immunogen Inc (IMGN)](/topic/$imgn) [AstraZeneca PLC (AZN)](/topic/$azn) [Novartis AG (NVS)](/topic/$nvs) [Merck & Co., Inc. (MRK)](/topic/$mrk) [SVB Financial Group (SIVBQ)](/topic/$sivb) [TG Therapeutics, Inc. (TGTX)](/topic/$tgtx) [Icosavax, Inc. (ICVX)](/topic/$icvx) [Cere Network (CERE)](/topic/$cere) [Johnson & Johnson (JNJ)](/topic/$jnj) [Intra-Cellular Therapies Inc. (ITCI)](/topic/$itci) [Sanofi (SNY)](/topic/sanofi) [Bristol-Myers Squibb Co (BMY)](/topic/$bmy) [Biohaven Pharmaceutical Holding Company Ltd. (BHVN)](/topic/$bhvn) [BridgeBio Pharma, Inc. Common Stock (BBIO)](/topic/$bbio) [Poseida Therapeutics, Inc. (PSTX)](/topic/$pstx) [Edgewise Therapeutics, Inc. (EWTX)](/topic/$ewtx) [Biogen Inc (BIIB)](/topic/$biib) ### Top Social Posts Top posts by engagements in the last [--] hours "Letter 005: Biotech Buckets investing investing" [Reddit Link](https://redd.it/pu971x) 2025-09-07T16:48Z [--] followers, [---] engagements "Humanigen ($HGEN) and Covid Therapeutics in Late [----] by DDD Biotechplays Biotechplays" [Reddit Link](https://redd.it/p83rwh) 2024-10-29T20:45Z [--] followers, [---] engagements "Dr. DD's thoughts on 3Q21 Earnings Call $KPTI KPTI KPTI" [Reddit Link](https://redd.it/qm2t1p) 2024-10-25T10:36Z [--] followers, [---] engagements "Dr. DD AACR Frontline Myelofibrosis Phase [--] Full Patient Readout 4/18/2023 - Biggest Opportunity for the Company but does the company have enough time KPTI KPTI" [Reddit Link](https://redd.it/12rck9l) 2023-10-27T04:03Z [--] followers, [----] engagements "Humanigen ($HGEN) and Covid Therapeutics in Late [----] by DDD FluentInFinance FluentInFinance" [Reddit Link](https://redd.it/p86dbu) 2024-12-01T09:16Z [--] followers, [--] engagements "SIERRA Oncology ($SRRA): Myelofibrosis Disease State Overview & One Company's Trash is Another's Treasure Biotechplays Biotechplays" [Reddit Link](https://redd.it/tq8rse) 2024-10-22T23:29Z [--] followers, [--] engagements "Dr. DD's Thoughts on Q4 and FY2022 $KPTI Earning's Call February [--] [----] KPTI KPTI" [Reddit Link](https://redd.it/113gnj9) 2023-09-14T23:15Z [--] followers, [----] engagements "COSTS Shaking the tree let's pray they become disciplined with costs only we can stop us now. Asymmetrical upside (NFA) if costs are under revenue with this many opportunities / Biomarker testing potential. Let's leave the option open of MAKING A RUN. $157MM [----] Rev get costs down KPTI KPTI" [Reddit Link](https://redd.it/1238m2c) 2025-07-25T01:58Z [--] followers, [--] engagements "Dr. DD Thoughts on Selinexor in Advanced Endometrial Cancer post SGO - RUBY/NRG-GY018 KPTI KPTI" [Reddit Link](https://redd.it/125b761) 2023-03-29T03:01Z [--] followers, [--] engagements "$KPTI CEO Richard Paulson joining $BLUE Board of Directors April [--] [----] KPTI KPTI" [Reddit Link](https://redd.it/1260ao4) 2023-03-29T20:50Z [--] followers, [--] engagements "Dr. DD $KPTI and $TGTX Meme KPTI KPTI" [Reddit Link](https://redd.it/12i92nm) 2023-04-11T05:00Z [--] followers, [--] engagements "Investor Webcast 4/18/23 for AACR Phase [--] MF Frontline Combination Data (Ruxolitinib and Selinexor) KPTI KPTI" [Reddit Link](https://redd.it/12m3vj5) 2023-04-14T17:01Z [--] followers, [---] engagements "AACR Phase [--] February Data cutoff for Frontline MF Selinexor and Ruxolitinib KPTI KPTI" [Reddit Link](https://redd.it/12qyoi1) 2023-04-18T18:08Z [--] followers, [---] engagements "Phase 1/3 Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis - ClinicalTrials.gov KPTI KPTI" [Reddit Link](https://redd.it/14n9j82) 2026-01-07T14:09Z [--] followers, [--] engagements "Open Letter to $KPTI CEO Richard Paulson KPTI KPTI" [Reddit Link](https://redd.it/151uan5) 2023-07-17T06:54Z [--] followers, [---] engagements "Dr. DD's Thoughts on ASCO Plenary SIENDO1 Update July [----] KPTI KPTI" [Reddit Link](https://redd.it/159yzg0) 2023-10-23T22:11Z [--] followers, [----] engagements "Dr. DD's Thoughts on Q2 [----] Earnings Call - beginnings of Financial Discipline KPTI KPTI" [Reddit Link](https://redd.it/15gco9h) 2023-08-02T15:57Z [--] followers, [----] engagements "Dr. DD's Thoughts on Karyopharm Therapeutics Department Goals [----] KPTI KPTI" [Reddit Link](https://redd.it/15mc3zs) 2023-08-09T11:03Z [--] followers, [--] engagements "Dr. DDs Notes and Thoughts on $KPTI at 14th Annual Jefferies in London KPTI KPTI" [Reddit Link](https://redd.it/17wff8h) 2023-11-16T05:46Z [--] followers, [--] engagements "Icosavax $ICVX bought by $AZN Astrazeneca $15 + $5 CVR. Makes RSV/ hMPV bivalent vaccine. Currently Phase [--] Biotechplays Biotechplays" [Reddit Link](https://redd.it/18ggexm) 2024-10-23T03:03Z [--] followers, [--] engagements "Dr. DD's Top [--] points from JPM24 KPTI KPTI" [Reddit Link](https://redd.it/193x709) 2024-11-07T15:56Z [--] followers, [--] engagements "Evaluating Myelofibrosis current SOC Navitoclax ($ABBV) and Pelabresib ($MOR / $NVS) KPTI KPTI" [Reddit Link](https://redd.it/1amxbix) 2024-02-09T20:09Z [--] followers, [--] engagements "XPORT-MF-034: selinexor + ruxolitinib combination therapy for MF KPTI KPTI" [Reddit Link](https://redd.it/1b3yhbx) 2024-03-01T16:28Z [--] followers, [--] engagements "Full enrollment for SIENDO2 EC-042 in 2H [----] is waaaay to late KPTI KPTI" [Reddit Link](https://redd.it/1bf1560) 2024-03-15T00:45Z [--] followers, [--] engagements "$AZN DUO-E results for pMMR Advanced Endometrial Cancer KPTI KPTI" [Reddit Link](https://redd.it/1bmdua2) 2024-03-24T06:07Z [--] followers, [--] engagements "Lenvatinib Combo Prolongs OS PFS in Advanced Endometrial Cancer Subgroups - spoiler pMMR was worse with Lenvatinib and Keytruda KPTI KPTI" [Reddit Link](https://redd.it/1bpi0o6) 2024-03-28T00:32Z [--] followers, [--] engagements "If $KPTI submitted Adv Endometrial Cancer pMMR WTP53 for AA to FDA (not approved just submitted). KPTI KPTI" [Reddit Link](https://redd.it/1byjefj) 2024-04-07T23:55Z [--] followers, [--] engagements "Interesting comments on ASCO SIENDO1 Update by Moffitt Chair KPTI KPTI" [Reddit Link](https://redd.it/1d8uk9x) 2024-06-05T16:45Z [--] followers, [--] engagements "Constructive Feedback on $KPTI a Recap - why does Dr. DD write KPTI KPTI" [Reddit Link](https://redd.it/1dcaan6) 2024-06-10T01:54Z [--] followers, [--] engagements "Questions for Analysts to ask Q2 [----] Earnings Call (historically first week in August) KPTI KPTI" [Reddit Link](https://redd.it/1ds2xer) 2024-06-30T14:53Z [--] followers, [--] engagements "MF SENTRY Phase [--] Trial at [--] sites KPTI KPTI" [Reddit Link](https://redd.it/1f2ihmj) 2024-08-27T14:29Z [--] followers, [--] engagements "Shifted focus to SENTRY (Phase [--] MF) KPTI KPTI" [Reddit Link](https://redd.it/1faffqz) 2024-09-06T13:39Z [--] followers, [--] engagements "From OncLive the Head of UCLA Gynecologic Oncology reasons for SLOW SIENDO2 KPTI KPTI" [Reddit Link](https://redd.it/1fdx8dd) 2025-02-14T01:43Z [--] followers, [--] engagements "Myelofibrosis - Historical Ruxolitinib SVR35 - please note only [--] large trials (200+ patients - highlighted below) KPTI KPTI" [Reddit Link](https://redd.it/1feqtc6) 2024-09-12T01:28Z [--] followers, [--] engagements "Potential Presentation of Phase [--] Myelofibrosis "Initial" Data Could they be wanting to present at ASH [----] KPTI KPTI" [Reddit Link](https://redd.it/1fpdxk7) 2024-09-25T20:06Z [----] followers, [--] engagements "Comparing MF Trials - $MOR MANIFEST-2 and $KPTI SENTRY KPTI KPTI" [Reddit Link](https://redd.it/1fpjq09) 2024-10-22T20:01Z [--] followers, [--] engagements "HIghbridge Capital with 9.7MM warrants representing 7.2% of all common shares (if exercised)- SEC 13G 10/25/2024 KPTI KPTI" [Reddit Link](https://redd.it/1gc143r) 2025-02-14T01:43Z [--] followers, [--] engagements "Dr. DD's thoughts on Q3 [----] Earnings Call - just ENROLL the Trials KPTI KPTI" [Reddit Link](https://redd.it/1gkec54) 2024-11-05T19:05Z [--] followers, [--] engagements "Timeline for NASDAQ Compliance KPTI KPTI" [Reddit Link](https://redd.it/1gnjqfq) 2024-11-09T20:55Z [----] followers, [--] engagements "$ABBV buyout of $CERE for Schizophrenia drug fails $8.7BN acquisition cost Abbvie previously pursued Myelofibrosis with Navitoclax KPTI KPTI" [Reddit Link](https://redd.it/1gp4ho5) 2024-11-11T21:59Z [--] followers, [--] engagements "Have a great weekend everybody KPTI KPTI" [Reddit Link](https://redd.it/1gxn8k3) 2024-11-23T00:46Z [----] followers, [--] engagements "Piper Sandler Dec 3rd [----] 11:30 AM EST KPTI KPTI" [Reddit Link](https://redd.it/1gzht0y) 2024-11-25T12:45Z [--] followers, [--] engagements "$BLUE does [--] for [--] reverse stock split Biotechplays Biotechplays" [Reddit Link](https://redd.it/1h75ynl) 2024-12-05T10:11Z [--] followers, [--] engagements "Chimerix $XMRX submits for Accelerated Approval (AA) Biotechplays Biotechplays" [Reddit Link](https://redd.it/1haomh3) 2025-07-23T02:23Z [--] followers, [--] engagements "J&J doubles down on neurological drugs with $14.6 billion Intra-Cellular deal $JNJ $ITCI Biotechplays Biotechplays" [Reddit Link](https://redd.it/1i1khar) 2025-01-15T00:17Z [--] followers, [--] engagements "Dr. DD First half [----] Thoughts - potential catalysts and pitfalls KPTI KPTI" [Reddit Link](https://redd.it/1ijg2t4) 2025-02-06T22:59Z [--] followers, [--] engagements "CEO poll View Poll(https://www.reddit.com/poll/1itk87a) KPTI KPTI" [Reddit Link](https://redd.it/1itk87a) 2025-02-19T23:38Z [----] followers, [--] engagements "Karyopharm Therapeutics reverse split [--] to [--]. Thanks Richard KPTI KPTI" [Reddit Link](https://redd.it/1ixf5rk) 2025-02-24T22:34Z [----] followers, [--] engagements "May [--] [----] Q1 [----] Earnings Call KPTI KPTI" [Reddit Link](https://redd.it/1ki33t2) 2025-05-08T22:27Z [--] followers, [--] engagements "2 more employees hired May 31st [----] KPTI KPTI" [Reddit Link](https://redd.it/1l2209h) 2025-06-03T03:40Z [--] followers, [--] engagements "Jefferies Conference Last minute KPTI KPTI" [Reddit Link](https://redd.it/1l2a33e) 2025-06-03T12:21Z [--] followers, [--] engagements "Why does Richard Paulson keep saying frontline Myelofibrosis is only a billion dollars KPTI KPTI" [Reddit Link](https://redd.it/1l4lv60) 2025-06-06T06:48Z [--] followers, [--] engagements "Canada going Generic Ozempic A Month Supply of Semaglutide (Weight Loss) for $54 Not Compounded made by Sandoz. Available in [----] [---] days. HIMS HIMS" [Reddit Link](https://redd.it/1lbqz7d) 2025-06-15T03:48Z [--] followers, [--] engagements "If you could get real generic Semaglutide pens for $54/month instead of compounded vials $199 locked in [--] months HimsWeightloss HimsWeightloss" [Reddit Link](https://redd.it/1lbtibs) 2025-06-15T06:20Z [--] followers, [--] engagements "SVP Michael Method Leaves $KPTI after [--] months to go to $BCYC KPTI KPTI" [Reddit Link](https://redd.it/1llk7s3) 2025-06-27T04:13Z [--] followers, [--] engagements "Karyopharm Announces Completion of Enrollment in the Phase [--] SENTRY Trial in Myelofibrosis KPTI KPTI" [Reddit Link](https://redd.it/1ndd4yr) 2025-12-21T08:28Z [--] followers, [--] engagements "YOUR THOUGHTS Now that MF Phase [--] trial is fully enrolled there are a few outcomes KPTI KPTI" [Reddit Link](https://redd.it/1ndscnx) 2025-12-21T08:28Z [--] followers, [--] engagements "Sanofi To Acquire Kadmon ($KDMN) at $9.50 per share Biotechplays Biotechplays" [Reddit Link](https://redd.it/pk4y8y) 2025-07-23T22:03Z [--] followers, [--] engagements "Clovis Oncology ($CLVS) Update & Hubris with Burnrate Biotechplays Biotechplays" [Reddit Link](https://redd.it/rfixo4) 2024-12-01T09:16Z [--] followers, [--] engagements "Options for December Expire 12/17/21 - Shorts want the price to drop and why it's dropped recently KPTI KPTI" [Reddit Link](https://redd.it/ri4tna) 2021-12-17T00:49Z [--] followers, [--] engagements "The ULTIMATE Guide to SIENDO & Endometrial Cancer + Stock Price effects KPTI KPTI" [Reddit Link](https://redd.it/sd3vns) 2024-12-01T09:16Z [--] followers, [---] engagements "Dr. DD's quick thoughts post SIENDO Regulatory Update KPTI KPTI" [Reddit Link](https://redd.it/t4n00z) 2024-12-01T09:16Z [--] followers, [--] engagements "Myovant Sciences ($MYOV) Shares Drop 20% After FDA Notice for Myfembree Biotechplays Biotechplays" [Reddit Link](https://redd.it/u2a507) 2024-12-05T17:42Z [--] followers, [--] engagements "Amphista Therapeutics makes strategic collaboration with Merck ($MRK) and Bristol Myers Squibb ($BMY) for Targeted Protein Degradation Therapeutics for up to $2.25BN Biotechplays Biotechplays" [Reddit Link](https://redd.it/uiy3qo) 2022-05-05T14:00Z [--] followers, [--] engagements "Dr. DD's Quick Thoughts on $KPTI Karyopharm Earnings in Q1 [----] KPTI KPTI" [Reddit Link](https://redd.it/uj9f1d) 2025-03-25T18:20Z [--] followers, [--] engagements "Pfizer ($PFE) to Acquire Biohaven Pharmaceuticals ($BHVN) - Stock up 70%+ pre-market Biotechplays Biotechplays" [Reddit Link](https://redd.it/umi56d) 2024-11-24T08:25Z [--] followers, [---] engagements "Tsunami Hypothesis #TsunamiHypothesis KPTI KPTI" [Reddit Link](https://redd.it/w3woiw) 2025-07-25T19:32Z [--] followers, [--] engagements "Dr. DD's thoughts on Q2 [----] Earnings Call KPTI KPTI" [Reddit Link](https://redd.it/wgdot7) 2024-10-23T02:19Z [--] followers, [---] engagements "Three's a company KPTI KPTI" [Reddit Link](https://redd.it/xmf46w) 2025-07-25T12:35Z [--] followers, [---] engagements "Dr. DD's thoughts on Phase [--] Selinexor and Jakafi Combo in newly diagnosed Myelofibrosis ASH [----] update KPTI KPTI" [Reddit Link](https://redd.it/yld699) 2026-01-08T10:41Z [--] followers, [--] engagements "Doctor DD's thoughts on $KPTI Post Raise KPTI KPTI" [Reddit Link](https://redd.it/1069m3q) 2023-09-15T03:11Z [--] followers, [----] engagements "Hostile Takeover of the Board coming Rubric Capital buying and things are getting interesting KPTI KPTI" [Reddit Link](https://redd.it/11173l7) 2024-10-23T02:19Z [--] followers, [--] engagements "Karyopharm has no exposure to Silicon Valley Bank ($KPTI $SIVB) KPTI KPTI" [Reddit Link](https://redd.it/11owc1h) 2024-10-27T11:49Z [--] followers, [--] engagements "Dr. DD's quick Barclays Notes KPTI KPTI" [Reddit Link](https://redd.it/11san5t) 2023-10-27T16:33Z [--] followers, [----] engagements "Dr. DD Going to be meme'in on twitter about the dilution all week please make sure to vote with your values and don't forget to vote Likes and Retweets appreciated to try and spread the word KPTI KPTI" [Reddit Link](https://redd.it/12g4doq) 2023-04-09T01:10Z [--] followers, [---] engagements "Dr. DD's Myelofibrosis Hands down the BIGGEST SHOT on goal left - Competition Status and Catalysts for Second Line MF KPTI KPTI" [Reddit Link](https://redd.it/12jqrkr) 2023-10-27T00:35Z [--] followers, [----] engagements "Hiring Continues - New SVP for Global Medical and Scientific Affairs Amama Sadiq MD MPH - granted [------] RSUs over [--] years KPTI KPTI" [Reddit Link](https://redd.it/13d9taw) 2023-10-02T02:35Z [--] followers, [---] engagements "Dr. DD Letter 006: How to use AI as a tool for Stock Research Biotechplays Biotechplays" [Reddit Link](https://redd.it/13vaamv) 2023-10-24T12:07Z [--] followers, [----] engagements "$IMGN earnings Q2 in Ovarian a Comparison for future $KPTI in Endometrial KPTI KPTI" [Reddit Link](https://redd.it/15ehrcb) 2024-10-22T19:56Z [--] followers, [--] engagements "Had some people message me guess Im famous CafePharma KPTI KPTI" [Reddit Link](https://redd.it/16epzin) 2023-09-12T05:30Z [--] followers, [---] engagements "New Endometrial Cancer VP Clinical Development Medical Lead KPTI KPTI" [Reddit Link](https://redd.it/16xavqb) 2024-11-24T12:58Z [--] followers, [--] engagements "Management Primer on Short Psychology Game Theory KPTI KPTI" [Reddit Link](https://redd.it/17rz5hp) 2024-12-01T05:00Z [--] followers, [----] engagements "Dr. DD Morphosys $MOR wants you to take both pills Biotechplays Biotechplays" [Reddit Link](https://redd.it/180bcf6) 2023-11-21T07:23Z [--] followers, [---] engagements "$ABBV buys $IMGN for $10Bn KPTI KPTI" [Reddit Link](https://redd.it/187iyoy) 2024-10-22T19:56Z [--] followers, [--] engagements "Abbvie $ABBV buys $IMGN for $10Bn [--] percent premium to last close Biotechplays Biotechplays" [Reddit Link](https://redd.it/187j03n) 2024-10-22T19:56Z [--] followers, [--] engagements "Another ESGO Presentation mentions Selinexor in changing landscape of Endometrial Cancer KPTI KPTI" [Reddit Link](https://redd.it/1bchgvr) 2024-12-25T14:49Z [--] followers, [--] engagements "LinkedIn Open Letter to Chairman of the Board Barry Greene $KPTI $SAGE KPTI KPTI" [Reddit Link](https://redd.it/1c4zi85) 2024-10-22T20:20Z [--] followers, [--] engagements "Dr. DD's notes on $KPTI Q1 [----] - Debt Refinancing Quarter KPTI KPTI" [Reddit Link](https://redd.it/1cnhncl) 2024-05-08T22:38Z [--] followers, [--] engagements "6:41 A CEO out of his depth KPTI KPTI" [Reddit Link](https://redd.it/1d3i360) 2024-05-29T17:42Z [--] followers, [--] engagements "Board Member Deepika has been selling a LOT of her shares Petition for Replacement Many on this board have more shares than that. Rubric Capital moved to kick her off of $MREO (she ended up staying) but need someone with institutional contacts KPTI KPTI" [Reddit Link](https://redd.it/1d9wvya) 2024-12-01T06:56Z [--] followers, [--] engagements "Karyopharm CEO Richard Paulson took over a company worth $1BN. It is now about to be removed from Russell [----] under his leadership KPTI KPTI" [Reddit Link](https://redd.it/1ddjuae) 2024-10-22T20:20Z [--] followers, [--] engagements "Apple Tree Partners discussion KPTI KPTI" [Reddit Link](https://redd.it/1ds5p6d) 2024-06-30T17:00Z [--] followers, [--] engagements "NCCN discussion KPTI KPTI" [Reddit Link](https://redd.it/1dtwbr5) 2025-03-31T11:20Z [--] followers, [--] engagements "10 Key Statistical Concepts for Biotech Investors Biotechplays Biotechplays" [Reddit Link](https://redd.it/1fibbvb) 2024-09-16T17:59Z [--] followers, [---] engagements "SENTRY Phase [--] MF Update KPTI KPTI" [Reddit Link](https://redd.it/1ggv5l4) 2024-11-01T02:11Z [--] followers, [--] engagements "$BBIO Attruby (acoramidis) a Near Complete TTR Stabilizer (90%) approved by FDA to Reduce Cardiovascular Death and Cardiovascular-related Hospitalization in ATTR-CM Patients Biotechplays Biotechplays" [Reddit Link](https://redd.it/1gxnfcg) 2024-11-24T12:10Z [--] followers, [--] engagements "$PSTX Poseidon Therapeutics bought out by Roche Biotechplays Biotechplays" [Reddit Link](https://redd.it/1h07mo3) 2024-11-26T09:12Z [--] followers, [--] engagements "FDA doesn't typically meet too much around Christmas. Possible to hear back about this sooner Phase [--] MM regulatory feedback KPTI KPTI" [Reddit Link](https://redd.it/1h0uje0) 2024-11-27T03:13Z [--] followers, [--] engagements "$BLUE which has Karyopharm CEO Richard Paulson as a board member being investigated by FDA KPTI KPTI" [Reddit Link](https://redd.it/1h1rkem) 2024-11-28T08:33Z [--] followers, [--] engagements "Please read $KPTI SEC Filing for 400MM Additional Shares and Reverse Split Vote from CEO Richard Paulson KPTI KPTI" [Reddit Link](https://redd.it/1h803zk) 2024-12-06T12:19Z [--] followers, [--] engagements "$EWTX Phase [--] data in Becker Muscular Dystrophy Biotechplays Biotechplays" [Reddit Link](https://redd.it/1hfgtrd) 2024-12-16T11:35Z [--] followers, [--] engagements "Chairman Barry Greene at $KPTI selling $SAGE where he is CEO for cheap to $BIIB Biogen after offer KPTI KPTI" [Reddit Link](https://redd.it/1hynnuw) 2025-01-11T04:09Z [--] followers, [--] engagements "Merck $MRK Keytruda sales significantly increased. MGMT specifically mentioned Endometrial Cancer multiple times (see below) KPTI KPTI" [Reddit Link](https://redd.it/1ipj3hj) 2025-02-14T19:43Z [--] followers, [--] engagements "Dr. DD's Thoughts on $KPTI 4th Quarter Earnings Call - Get to Work KPTI KPTI" [Reddit Link](https://redd.it/1ithah1) 2025-02-19T21:37Z [--] followers, [--] engagements "Please like and retweet if you want to ask Chairman Barry Greene to step down KPTI KPTI" [Reddit Link](https://redd.it/1ixfluj) 2025-02-24T22:54Z [--] followers, [--] engagements "The Karyopharm Board just awarded [-----] shares was valued $159000 and [-----] options to CEO Richard Paulson. Since May [--] [----] the stock is down 95%. KPTI KPTI" [Reddit Link](https://redd.it/1j3v5df) 2025-03-05T04:42Z [--] followers, [--] engagements "CEO Richard Paulson could stop the bleeding at any time but he won't KPTI KPTI" [Reddit Link](https://redd.it/1jl9p2u) 2025-03-27T17:37Z [--] followers, [--] engagements "XPORT-MF-044 Phase [--] MF low platelets - Slide removed between Q4 [----] and Q1 [----]. In Q3 [----] stated preliminary data in [----] / early [----] KPTI KPTI" [Reddit Link](https://redd.it/1ksdhu9) 2025-05-22T00:25Z [--] followers, [--] engagements "Myelofibrosis Update via Corporate Slide Deck June [--] [----] and Other Agent Comparisons KPTI KPTI" [Reddit Link](https://redd.it/1l7r1am) 2025-06-10T05:46Z [--] followers, [--] engagements "Open Letter to CEO Richard Paulson years ago. KPTI KPTI" [Reddit Link](https://redd.it/1lpnz4d) 2025-07-02T05:41Z [--] followers, [--] engagements "Someone is accumulating on low volume from $32MC low up 80% KPTI KPTI" [Reddit Link](https://redd.it/1mvmi84) 2025-08-20T18:19Z [--] followers, [--] engagements "Market cap $64.69MM after 18% gain today KPTI KPTI" [Reddit Link](https://redd.it/1n0x36y) 2025-08-26T21:05Z [--] followers, [--] engagements "Down to the wire KPTI KPTI" [Reddit Link](https://redd.it/1npl0rr) 2025-09-24T19:07Z [--] followers, [--] engagements "Healthcare Royalty KPTI KPTI" [Reddit Link](https://redd.it/1nrd3nf) 2025-11-11T06:23Z [--] followers, [--] engagements "Runway thoughts KPTI KPTI" [Reddit Link](https://redd.it/1obpxeu) 2025-10-20T19:49Z [--] followers, [--] engagements "Dr. DD's thoughts on Q3 [----] Earnings Call KPTI KPTI" [Reddit Link](https://redd.it/1onjmt7) 2025-11-04T12:02Z [--] followers, [--] engagements "Clovis ($CLVS) Oncology: A Case Study of Hubris Biotechplays Biotechplays" [Reddit Link](https://redd.it/og0dbb) 2024-12-01T09:16Z [--] followers, [---] engagements "Karyopharm ($KPTI) The Biggest Turnaround Opportunity in Biotech by DDD Biotechplays Biotechplays" [Reddit Link](https://redd.it/oq8rs1) 2024-12-01T09:16Z [--] followers, [---] engagements "Cortexyme ($CRTX) GAIN Trial to make or break the Stock (Q42021) by DDD Biotechplays Biotechplays" [Reddit Link](https://redd.it/ou2l1n) 2024-11-07T18:25Z [--] followers, [---] engagements "Cortexyme ($CRTX) GAIN Trial to make or break the Stock (Q42021) by DDD FluentInFinance FluentInFinance" [Reddit Link](https://redd.it/oucwth) 2024-12-01T09:16Z [--] followers, [--] engagements "Letter 002: Discerning types of Biotech Plays Biotechplays Biotechplays" [Reddit Link](https://redd.it/owhmth) 2024-10-23T03:56Z [--] followers, [---] engagements "Letter 002: Discerning types of Biotech Plays FluentInFinance FluentInFinance" [Reddit Link](https://redd.it/owm6kp) 2024-10-23T03:56Z [--] followers, [--] engagements "Dr. Due Diligence or How I Learned to Stop Worrying and Love $KPTI Biotechplays Biotechplays" [Reddit Link](https://redd.it/p3h9bn) 2024-11-29T17:08Z [--] followers, [---] engagements "Oncolytics Biotech ($ONCY) One Piece Away from Being a Great Company by DDD Biotechplays Biotechplays" [Reddit Link](https://redd.it/ph6cdl) 2024-12-01T09:16Z [--] followers, [----] engagements "Letter 004: Biotech Venture Capital Trends and How it Impacts your Investments Biotechplays Biotechplays" [Reddit Link](https://redd.it/pkxc7m) 2024-12-01T09:16Z [--] followers, [---] engagements "Karyopharm ($KPTI) Bull & Bear Investment Thesis KPTI KPTI" [Reddit Link](https://redd.it/ppw81p) 2024-12-01T09:16Z [--] followers, [--] engagements "Karyopharm ($KPTI) Bull & Bear Investment Thesis FluentInFinance FluentInFinance" [Reddit Link](https://redd.it/prgrdy) 2024-12-01T09:16Z [--] followers, [--] engagements "Letter 005: Biotech Buckets stocks stocks" [Reddit Link](https://redd.it/pu99th) 2024-12-01T09:16Z [--] followers, [---] engagements "Letter 005: Biotech Buckets by Dr. DD FluentInFinance FluentInFinance" [Reddit Link](https://redd.it/pukdqn) 2021-09-24T14:00Z [--] followers, [--] engagements "Letter 005: Biotech Buckets by Dr. DD Biotechplays Biotechplays" [Reddit Link](https://redd.it/pukdqs) 2024-12-01T09:16Z [--] followers, [---] engagements "Board Activity - Removal of Mikael Dolsten MD PhD & Addition of Peter K Honig MD MPH KPTI KPTI" [Reddit Link](https://redd.it/rbbteg) 2025-01-07T22:43Z [--] followers, [---] engagements "FDA grants Calliditas Therapeutics ($CALT) Accelerated Approval of TARPEYO (budesonide) to Reduce Proteinuria in IgA Nephropathy Biotechplays Biotechplays" [Reddit Link](https://redd.it/rhdxgw) 2026-01-24T01:09Z [--] followers, [--] engagements "Regeneron to Acquire Checkmate Pharmaceuticals and Its Investigational Immune Activator for Potential Use in Multiple Tumor Types ($250MM) Biotechplays Biotechplays" [Reddit Link](https://redd.it/u7hgfk) 2026-01-24T02:24Z [--] followers, [--] engagements "$425MM Market Cap today $KPTI $100MM Revenue last year from US Alone KPTI KPTI" [Reddit Link](https://redd.it/ulv6h3) 2025-08-08T19:39Z [--] followers, [--] engagements "Director Deepika Pakianathan and VC investor sold 538K+ shares still owns 5368MM Shares of $KPTI KPTI KPTI" [Reddit Link](https://redd.it/v9q2lp) 2025-12-08T22:51Z [--] followers, [--] engagements "Investor Relations doesn't have it listed but CEO RP speaking at Longwood (moderated by Chen Schor - board member) - 9/21/2022 at 9:50 AM EST - more information in comments KPTI KPTI" [Reddit Link](https://redd.it/xjm2rr) 2022-09-20T22:03Z [--] followers, [---] engagements "MDS - quick update since VP Medical Strategy - MDS Q3 [----] KPTI KPTI" [Reddit Link](https://redd.it/xrn9as) 2024-12-01T09:16Z [--] followers, [--] engagements "Clovis Oncology ($CLVS) on earnings call today - we will run out of cash in January [----] (2 months until bankruptcy- shares slide to $0.27 - 71%+ loss in one day Biotechplays Biotechplays" [Reddit Link](https://redd.it/yqvoog) 2024-10-22T23:19Z [--] followers, [--] engagements "Doctor DD's thoughts on $KPTI Post Raise Thoughts post raise and ASH (written December 2022) Pros: Company currently has about $300MM cash Company is valued at about $300MM The Senior Convertible Notes (debt) are due 06/2025 I keep hearing binary for MF November Trial - but to be honest I do not see it as binary. This is not a preclinical biotech it is a commercial biotech. The company has an approved agent that will likely bring in $160MM in [----]. This number I believe will grow not diminish. Hopefully they can bring in $200MM in [----]. Additionally for MM agents knowing who will respond is" [Reddit Link](https://redd.it/1069m3q) 2023-01-08T04:25Z [----] followers, [--] engagements "Karyopharm has no exposure to Silicon Valley Bank ($KPTI $SIVB)" [Reddit Link](https://redd.it/11owc1h) 2023-03-11T21:56Z [--] followers, [--] engagements "New Karyopharm VP President of Quality Hassan Ansari (another AbbVie Hire)" [Reddit Link](https://redd.it/12d5dvu) 2023-04-06T01:50Z [----] followers, [--] engagements "Dr. DD's Myelofibrosis Hands down the BIGGEST SHOT on goal left - Competition Status and Catalysts for Second Line MF I wrote up quite a bit when I recommended $SRRA last year(https://www.reddit.com/r/Biotechplays/comments/tq8rse/sierra_oncology_srra_myelofibrosis_disease_state/) before their $1.9 Billion buyout by $GSK(https://www.reuters.com/business/healthcare-pharmaceuticals/gsk-buy-sierra-oncology-19-billion-2022-04-13/). # For ease - the important overview of Myelofibrosis from that write-up **Myelofibrosis Overview**: Myelofibrosis is a terrible rare bone cancer. Im going to give you a" [Reddit Link](https://redd.it/12jqrkr) 2023-04-12T16:03Z [--] followers, [--] engagements "Dr. DD AACR Frontline Myelofibrosis Phase [--] Full Patient Readout 4/18/2023 - Biggest Opportunity for the Company but does the company have enough time # Third Time's a Charm I saw everyone tweeting and giving their thoughts immediately after the press release. I wanted to listen to the call before I made any snap judgements. **I've now listened three times to try and get the deepest and hidden insights.** Read below and tell me what you think # Tea Leaves from China (Antengene) drank at the City of Hope My reading of the tea leaves was correct so that's a huge weight off my shoulders. The" [Reddit Link](https://redd.it/12rck9l) 2023-04-19T01:51Z [----] followers, [--] engagements "Dr. DD Letter 006: How to use AI as a tool for Stock Research To Those Who Wish to learn I feel like I may be giving away a secret. but. here it goes. Earlier today I had a twitter conversation(https://twitter.com/sentivcapital/status/1663230898702106634) about AI in regards to potential for future impact on stocks. I received a lot of DMs and to be honest I've missed posting in r/Biotechplays and thought I'd write up a little how to guide. First off if you're reading this in the future most of this will be outdated. Focus less on the details and more on the framework / thinking. Secondly I" [Reddit Link](https://redd.it/13vaamv) 2023-05-29T23:41Z [----] followers, [--] engagements "Dr. DD $MOR Morphosys MEGATHREAD - includes updated thoughts on $KPTI in Myelofibrosis" [Reddit Link](https://redd.it/142tg1y) 2023-06-06T21:13Z [----] followers, [--] engagements "State Street Corporation SEC 13G - what it means 👇🏽" [Reddit Link](https://redd.it/14w2no9) 2023-07-10T18:51Z [----] followers, [--] engagements "Open Letter to $KPTI CEO Richard Paulson To Karyopharm Therapeutics CEO Richard Paulson I write to you today because I want you to strongly consider risk aversion. When you see my writings how does it make you feel If it causes uneasiness that is your intuition speaking to you. I only tell what I believe to be the absolute truth from my perspective. Do you think there is a reason why so many people including Karyopharm Therapeutics employees read my writing Does it resonate with them When I post that the stock price has gone down from $9.55 to $1.60 under your leadership that probably doesnt" [Reddit Link](https://redd.it/151uan5) 2023-07-17T06:54Z [----] followers, [--] engagements "$MOR $KPTI and Investment Philosophy Megathread with note of appreciation - Dr. DD" [Reddit Link](https://redd.it/152lbtd) 2023-07-18T02:12Z [----] followers, [--] engagements "$GILD agent Magrolimab (CD47) bought from FortySeven for $4.9BN - Phase [--] Trial in MDS High Risk Discontinued. - Competitor to $KPTI Eltanexor" [Reddit Link](https://redd.it/156a4zw) 2023-07-22T04:33Z [----] followers, [--] engagements "Dr. DD's Thoughts on ASCO Plenary SIENDO1 Update July 2023" [Reddit Link](https://redd.it/159yzg0) 2023-07-26T07:43Z [----] followers, [----] engagements "Dr. DD's Thoughts on Q2 [----] Earnings Call - beginnings of Financial Discipline" [Reddit Link](https://redd.it/15gco9h) 2023-08-02T15:57Z [----] followers, [----] engagements "Dr. DD's Thoughts on Karyopharm Therapeutics Department Goals 2023" [Reddit Link](https://redd.it/15mc3zs) 2023-08-09T11:03Z [----] followers, [---] engagements "Letter 005: Biotech Buckets September 23rd [----] To Those Who Wish to Learn *If you dont know what you want you will probably never get it.* - Justice Oliver Wendell Holmes Everyone sees biotech investing as largely risky and it is but that is not why you are here(https://www.youtube.com/watchv=4nFNJSIaR7c). There are a million ways for you to lose money and only a few for you to make money. With that being said at the root of biotechs there are essentially [--] categories - New Frontier Platform Copycat Spinoffs and Behemoths with varying potential investment returns. **New Frontier:** These" [Reddit Link](https://redd.it/pu99th) 2021-09-24T01:18Z [----] followers, [--] engagements "Letter 005: Biotech Buckets by Dr. DD September 24th [----] **DoctorDueDiligence**(https://docs.google.com/forms/d/e/1FAIpQLSfaW9CrhylAMyHwsT36VSmEH9cF4cZmnq_wCKkN7stbZxlZKg/viewformusp=sf_link) To Those Who Wish to Learn *If you dont know what you want you will probably never get it.* - Justice Oliver Wendell Holmes Everyone sees biotech investing as largely risky and it is but that is not why you are here(https://www.youtube.com/watchv=4nFNJSIaR7c). There are a million ways for you to lose money and only a few for you to make money. With that being said at the root of biotechs there are" [Reddit Link](https://redd.it/pukdqn) 2021-09-24T14:00Z [----] followers, [--] engagements "Dr. DD SVB Quick Feedback February [--] [----] # Sohanya Chang was the best presenter today * Had adequate but tough questions and had smart answers - Community Oncology is defensible and likely not to get T-cell therapy there. * Seems more confident than earlier last year * Fleshed out Xpovio pre and post Car-T benefits * While the low end of revenue projections is static (same as 2022) hopefully they under promise and over deliver. MM is a slow building disease state area. Sales specialists usually do better over time (relationship knowledge disease state). Here's to [----] # Mike Mason * I don't" [Reddit Link](https://redd.it/114ipuw) 2023-02-17T12:01Z [----] followers, [--] engagements "Karyopharm Announces Updated Selinexor Data in Patients with Treatment-Nave Myelofibrosis to be Presented at AACR 2023" [Reddit Link](https://redd.it/11rfjk2) 2023-03-15T00:11Z [----] followers, [---] engagements "Dr. DD Is Eltanexor a Dark Horse MDS Interim Data coming soon The deeper I dive the more I find out. I originally expected the Interim Analysis of [--] patients (expected Q2 2023) was a toss-up. **The more I go back and look at older posters and publications the more I think we might have a dark horse.** # What we know so far * Second Generation XPO1 Inhibitor * Animal models have shown that there is less weight loss than selinexor = hypothesized it does not cross CNS as much = lower side effects * Has been dosed much more frequently in humans without significant increase in ADEs (caveat -" [Reddit Link](https://redd.it/12855i0) 2023-04-01T00:19Z [----] followers, [--] engagements "Poll What do you think the SVR35 will be of the [--] patient update at AACR 2023" [Reddit Link](https://redd.it/12f67f0) 2023-04-08T01:01Z [----] followers, [---] engagements "Dr. DD Poll on $KPTI CEO Richard Paulson KPTI KPTI" [Reddit Link](https://redd.it/12i1dfo) 2023-04-10T23:58Z [----] followers, [--] engagements "Dr. DD Twitter Thread on my thoughts on Shorts and MF before AACR Poster - I'M NOT LEAVING 🤣" [Reddit Link](https://redd.it/12krrq0) 2023-04-13T14:51Z [--] followers, [---] engagements "An Open Letter to the Board" [Reddit Link](https://redd.it/1387pep) 2023-05-05T02:20Z [----] followers, [----] engagements "Meme Theme Vote KPTI KPTI" [Reddit Link](https://redd.it/13ccgr7) 2023-05-09T02:17Z [----] followers, [--] engagements "How to Stem the Bleeding of $KPTI - The Answers Right now with **no near term catalysts** and **likely dilution coming up Management must act.** But how can you act when you have no trial readouts and you just lowered guidance If you are leading a company and you believe it to be undervalued **Buy the stock.** This is something that multiple c-suite (and Board) could do and it would show confidence that the stock is undervalued. The more bought the more confidence the more the stock moves. This would be an immediate move and if it goes up high enough could dilute at that point if need be. I" [Reddit Link](https://redd.it/13hpvvd) 2023-05-14T22:47Z [----] followers, [---] engagements "Flurry of Form 4s for Board of Directors (SEC Form 4s 5/25/2023)" [Reddit Link](https://redd.it/13rtnbg) 2023-05-25T21:16Z [----] followers, [---] engagements "McDreamy Charity sponsored by $KPTI (presenting sponsor much more then even Amgen Spent at $100000) SVP(s) and C-suite headed to Main to drink with Patrick Dempsey" [Reddit Link](https://redd.it/14nd4yx) 2023-06-30T21:46Z [----] followers, [---] engagements "My Most Viewed LinkedIn Post Ever - even current and former $KPTI high level employees are liking. #FinancialDiscipline #McDreamy Asking Lead $KPTI Director Barry Greene to evaluate Financial Spending and Discipline after hyperlocal Patrick Dempsey focused Charity Spending to be Presenting Sponsor" [Reddit Link](https://redd.it/14rkzaw) 2023-07-05T19:37Z [----] followers, [---] engagements "$GILD agent Magrolimab (CD47) bought from FortySeven for $4.9BN - Phase [--] Trial in MDS High Risk Discontinued. - Competitor to $KPTI Eltanexor" [Reddit Link](https://redd.it/156a4zw) 2023-07-24T10:37Z [----] followers, [----] engagements "Breaking Bad Dr. DD Crossover $KPTI Meme KPTI KPTI" [Reddit Link](https://redd.it/162pj54) 2023-08-27T12:47Z [----] followers, [---] engagements "Letter 007: On the Nature of Value in Biotech To Those Who Wish to Learn If the market is efficient then all companies are accurately priced. If they are not why When a buyout happens in biotech is there a premium If there is a premium then is the market truly efficient It means that there was one or more companies that strongly believe that the biotech is *undervalued*. Biotech compared to other areas has a higher premium during buyout. It is not unusual to see 100% premium. This means that biotech in general is more affected by the *perception* rather than the true *value.* Why [--]. Consumer" [Reddit Link](https://redd.it/165df5w) 2023-08-30T12:32Z [----] followers, [----] engagements "Comments on what Management can do to help stock price $KPTI" [Reddit Link](https://redd.it/16cljtp) 2023-09-07T17:22Z [----] followers, [---] engagements "Dr. DD's Thoughts on Karyopharm $KPTI September [----] Investor Calls . KPTI KPTI" [Reddit Link](https://redd.it/16iwogr) 2023-09-14T22:55Z [----] followers, [--] engagements "DoctorDueDiligence on X In a widely expected move momelotinib was approved in an unexpected move super broad label $GSK $SRRA #FDA Myelofibrosis KPTI KPTI" [Reddit Link](https://redd.it/16jqfcz) 2023-09-15T22:07Z [--] followers, [--] engagements "New Board Member Zhen Su MD MBA (CEO Marengo Therapeutics + loves Apple Tree Partners) giving two talks recently (details in body)" [Reddit Link](https://redd.it/16mbjsp) 2023-09-18T23:55Z [----] followers, [---] engagements "Doctor DueDiligence on LinkedIn: SIENDO2 needs more SITES 51/85 Challenge and BANGING THE DRUM" [Reddit Link](https://redd.it/16n751h) 2023-09-20T00:31Z [----] followers, [---] engagements "The drum beats on - new position created [--] day after for Site Recruitment - Senior Manager Site Relationship & Recruitment Lead" [Reddit Link](https://redd.it/16p2bjw) 2023-09-22T05:49Z [----] followers, [---] engagements "20th IMS Abstracts - [--] Abstracts Multiple Myeloma" [Reddit Link](https://redd.it/16wi0oi) 2023-09-30T21:12Z [----] followers, [--] engagements "Senior Manager Site Relationship & Recruitment Lead - job tips for $KPTI" [Reddit Link](https://redd.it/179etdi) 2023-10-16T19:46Z [----] followers, [---] engagements "The 9th Board Member - Zhen Su MBA MD" [Reddit Link](https://redd.it/179paqo) 2023-10-17T03:45Z [----] followers, [---] engagements "News High Risk MDS study + Eltanexor Guidance" [Reddit Link](https://redd.it/17ad44v) 2023-10-18T00:19Z [----] followers, [---] engagements "LinkedIn Letter to $KPTI Chairman Barry Greene as Stock Price hits all time low - $0.80 KPTI KPTI" [Reddit Link](https://redd.it/17gi3n9) 2023-10-25T23:11Z [----] followers, [--] engagements "Impacting T-cell fitness in multiple myeloma: potential roles for selinexor and XPO1 inhibitors" [Reddit Link](https://redd.it/17h61if) 2023-10-26T20:38Z [--] followers, [---] engagements "$KPTI Earnings" [Reddit Link](https://redd.it/17l0o4q) 2023-11-01T01:13Z [----] followers, [--] engagements "Society for Immunotherapy of Cancer (SITC) on LinkedIn: #biotech #io - Zhen Su MD MBA in NYC KPTI KPTI" [Reddit Link](https://redd.it/17lnrem) 2023-11-01T22:10Z [----] followers, [--] engagements "Q3 Earnings Call - post your thoughts KPTI KPTI" [Reddit Link](https://redd.it/17lxdmn) 2023-11-02T06:32Z [----] followers, [--] engagements "Dr. DDs Thoughts on $KPTI Q3 [----] Earning Call" [Reddit Link](https://redd.it/17mopd1) 2023-11-03T06:24Z [----] followers, [----] engagements "Well I know the stock is down near [--] cents but on the bright side remember when $KPTI was the official presenting partner for the McDreamy charity Hes now Peoples Sexiest Man Alive 🤣" [Reddit Link](https://redd.it/17qt3nz) 2023-11-08T19:13Z [----] followers, [---] engagements "A Letter of Appreciation" [Reddit Link](https://redd.it/17u8brz) 2023-11-13T11:06Z [----] followers, [---] engagements "Positives for End of Year [----] $KPTI **Wider appreciation for T cell fitness** https://www.reddit.com/r/KPTI/s/ICY7k90sbj This is an area of research in Multiple Myeloma but basically MM is a non curable disease state. The immune system is highly important for cancer and cancer growth. Older patients have worse immune systems so that is why they generally have higher incidence rates of cancer. Many therapies focus on using the immune system this can lead to burnout. Other therapies directly hurt fast growing cells like T cells - these are chemotherapeutic in nature. There is a deep growing" [Reddit Link](https://redd.it/17uz48k) 2023-11-14T10:06Z [----] followers, [----] engagements "Apple Tree Partners - the 9th Board Member Zhen Su Michael Kauffman Barry Greene" [Reddit Link](https://redd.it/17vq3eq) 2023-11-15T09:36Z [----] followers, [---] engagements "MEME Some Men just want to See the World Burn" [Reddit Link](https://redd.it/17yr00z) 2023-11-19T06:39Z [----] followers, [---] engagements "Posting lots of $KPTI memes today :)" [Reddit Link](https://redd.it/182u3xt) 2023-11-24T15:06Z [----] followers, [---] engagements "Need a strong ASH 2023" [Reddit Link](https://redd.it/1842ijp) 2023-11-26T04:28Z [----] followers, [---] engagements "SIENDO2 life calculation cost for delays (oversimplified)" [Reddit Link](https://redd.it/185xp4i) 2023-11-28T14:45Z [----] followers, [---] engagements "Roche to buy Obesity Biotech Carmot Therapeutics for $2.7BN upfront and potential additional $400MM" [Reddit Link](https://redd.it/18aei14) 2023-12-04T06:44Z [----] followers, [----] engagements "Happy Holidays" [Reddit Link](https://redd.it/18dg8hz) 2023-12-08T06:01Z [----] followers, [---] engagements "$KPTI Post ASH data desert what I would do if I was management - Leadership for Execution needed I think if the leadership doesn't take action it is very possible a reverse share occurs if it stays below $1. By action (NFA what I would do personally): Convert some of salary to equity or buy a large buy on open market Push SIENDO2. This means trial sites and enrollment. Given the likely power you (if you execute) get this to read out quicker. Myelofibrosis I think won't read out by estimated timeline. [--] sites What is going on with Clin Ops JPM needs to be executed well. You need to generate" [Reddit Link](https://redd.it/18eu83d) 2023-12-10T03:14Z [----] followers, [--] engagements "What do you want to hear from $KPTI Management at JPM I'd love to hear *color on number of SIENDO2 patients enrolled and projected full enrollment *MDS Guidance *CCO either increasing sales or getting out of the way (assuming Q4 announced) *Cost cutting *MF update (Phase [--] and 3) *Up to date site count of all trials *Potentially seeking sale of company or ATP involvement and update *Form 4s of retail buying by management (NFA) *Repeat NCCN category [--] update and provide color on T cell fitness *have another top call with key KOLs for SIENDO1 data planned and or announce FDA sNDA if when OS" [Reddit Link](https://redd.it/18xelwv) 2024-01-03T08:33Z [----] followers, [--] engagements "Need a TEAM member to show up and get costs down. Need: care about stock can use excel persuasive Vince Vaughn was not available KPTI KPTI" [Reddit Link](https://redd.it/19ec65w) 2024-01-24T08:09Z [----] followers, [--] engagements "$1 Meme Team Hot TEAM Summer 🔥 How good was Joaquin in this though KPTI KPTI" [Reddit Link](https://redd.it/1ahwp72) 2024-02-03T13:59Z [----] followers, [--] engagements Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing
@DoctorDueDiligence DoctorDueDiligenceDoctorDueDiligence posts on Reddit about $kpti, linkedin, ceo, $abbv the most. They currently have [-----] followers and [---] posts still getting attention that total [---] engagements in the last [--] hours.
Social category influence finance stocks technology brands social networks cryptocurrencies travel destinations currencies exchanges countries automotive brands
Social topic influence $kpti #13, linkedin, ceo, $abbv, debt, investment, $fro, $sage, $crtx #1, $mor
Top accounts mentioned or mentioned by @duedoctor
Top assets mentioned AbbVie Inc (ABBV) Frontline Ltd. (FRO) Sage Therapeutics, Inc (SAGE) Bluefin (BLUE) Pfizer, Inc. (PFE) Immunogen Inc (IMGN) AstraZeneca PLC (AZN) Novartis AG (NVS) Merck & Co., Inc. (MRK) SVB Financial Group (SIVBQ) TG Therapeutics, Inc. (TGTX) Icosavax, Inc. (ICVX) Cere Network (CERE) Johnson & Johnson (JNJ) Intra-Cellular Therapies Inc. (ITCI) Sanofi (SNY) Bristol-Myers Squibb Co (BMY) Biohaven Pharmaceutical Holding Company Ltd. (BHVN) BridgeBio Pharma, Inc. Common Stock (BBIO) Poseida Therapeutics, Inc. (PSTX) Edgewise Therapeutics, Inc. (EWTX) Biogen Inc (BIIB)
Top posts by engagements in the last [--] hours
"Letter 005: Biotech Buckets investing investing"
Reddit Link 2025-09-07T16:48Z [--] followers, [---] engagements
"Humanigen ($HGEN) and Covid Therapeutics in Late [----] by DDD Biotechplays Biotechplays"
Reddit Link 2024-10-29T20:45Z [--] followers, [---] engagements
"Dr. DD's thoughts on 3Q21 Earnings Call $KPTI KPTI KPTI"
Reddit Link 2024-10-25T10:36Z [--] followers, [---] engagements
"Dr. DD AACR Frontline Myelofibrosis Phase [--] Full Patient Readout 4/18/2023 - Biggest Opportunity for the Company but does the company have enough time KPTI KPTI"
Reddit Link 2023-10-27T04:03Z [--] followers, [----] engagements
"Humanigen ($HGEN) and Covid Therapeutics in Late [----] by DDD FluentInFinance FluentInFinance"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"SIERRA Oncology ($SRRA): Myelofibrosis Disease State Overview & One Company's Trash is Another's Treasure Biotechplays Biotechplays"
Reddit Link 2024-10-22T23:29Z [--] followers, [--] engagements
"Dr. DD's Thoughts on Q4 and FY2022 $KPTI Earning's Call February [--] [----] KPTI KPTI"
Reddit Link 2023-09-14T23:15Z [--] followers, [----] engagements
"COSTS Shaking the tree let's pray they become disciplined with costs only we can stop us now. Asymmetrical upside (NFA) if costs are under revenue with this many opportunities / Biomarker testing potential. Let's leave the option open of MAKING A RUN. $157MM [----] Rev get costs down KPTI KPTI"
Reddit Link 2025-07-25T01:58Z [--] followers, [--] engagements
"Dr. DD Thoughts on Selinexor in Advanced Endometrial Cancer post SGO - RUBY/NRG-GY018 KPTI KPTI"
Reddit Link 2023-03-29T03:01Z [--] followers, [--] engagements
"$KPTI CEO Richard Paulson joining $BLUE Board of Directors April [--] [----] KPTI KPTI"
Reddit Link 2023-03-29T20:50Z [--] followers, [--] engagements
"Dr. DD $KPTI and $TGTX Meme KPTI KPTI"
Reddit Link 2023-04-11T05:00Z [--] followers, [--] engagements
"Investor Webcast 4/18/23 for AACR Phase [--] MF Frontline Combination Data (Ruxolitinib and Selinexor) KPTI KPTI"
Reddit Link 2023-04-14T17:01Z [--] followers, [---] engagements
"AACR Phase [--] February Data cutoff for Frontline MF Selinexor and Ruxolitinib KPTI KPTI"
Reddit Link 2023-04-18T18:08Z [--] followers, [---] engagements
"Phase 1/3 Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis - ClinicalTrials.gov KPTI KPTI"
Reddit Link 2026-01-07T14:09Z [--] followers, [--] engagements
"Open Letter to $KPTI CEO Richard Paulson KPTI KPTI"
Reddit Link 2023-07-17T06:54Z [--] followers, [---] engagements
"Dr. DD's Thoughts on ASCO Plenary SIENDO1 Update July [----] KPTI KPTI"
Reddit Link 2023-10-23T22:11Z [--] followers, [----] engagements
"Dr. DD's Thoughts on Q2 [----] Earnings Call - beginnings of Financial Discipline KPTI KPTI"
Reddit Link 2023-08-02T15:57Z [--] followers, [----] engagements
"Dr. DD's Thoughts on Karyopharm Therapeutics Department Goals [----] KPTI KPTI"
Reddit Link 2023-08-09T11:03Z [--] followers, [--] engagements
"Dr. DDs Notes and Thoughts on $KPTI at 14th Annual Jefferies in London KPTI KPTI"
Reddit Link 2023-11-16T05:46Z [--] followers, [--] engagements
"Icosavax $ICVX bought by $AZN Astrazeneca $15 + $5 CVR. Makes RSV/ hMPV bivalent vaccine. Currently Phase [--] Biotechplays Biotechplays"
Reddit Link 2024-10-23T03:03Z [--] followers, [--] engagements
"Dr. DD's Top [--] points from JPM24 KPTI KPTI"
Reddit Link 2024-11-07T15:56Z [--] followers, [--] engagements
"Evaluating Myelofibrosis current SOC Navitoclax ($ABBV) and Pelabresib ($MOR / $NVS) KPTI KPTI"
Reddit Link 2024-02-09T20:09Z [--] followers, [--] engagements
"XPORT-MF-034: selinexor + ruxolitinib combination therapy for MF KPTI KPTI"
Reddit Link 2024-03-01T16:28Z [--] followers, [--] engagements
"Full enrollment for SIENDO2 EC-042 in 2H [----] is waaaay to late KPTI KPTI"
Reddit Link 2024-03-15T00:45Z [--] followers, [--] engagements
"$AZN DUO-E results for pMMR Advanced Endometrial Cancer KPTI KPTI"
Reddit Link 2024-03-24T06:07Z [--] followers, [--] engagements
"Lenvatinib Combo Prolongs OS PFS in Advanced Endometrial Cancer Subgroups - spoiler pMMR was worse with Lenvatinib and Keytruda KPTI KPTI"
Reddit Link 2024-03-28T00:32Z [--] followers, [--] engagements
"If $KPTI submitted Adv Endometrial Cancer pMMR WTP53 for AA to FDA (not approved just submitted). KPTI KPTI"
Reddit Link 2024-04-07T23:55Z [--] followers, [--] engagements
"Interesting comments on ASCO SIENDO1 Update by Moffitt Chair KPTI KPTI"
Reddit Link 2024-06-05T16:45Z [--] followers, [--] engagements
"Constructive Feedback on $KPTI a Recap - why does Dr. DD write KPTI KPTI"
Reddit Link 2024-06-10T01:54Z [--] followers, [--] engagements
"Questions for Analysts to ask Q2 [----] Earnings Call (historically first week in August) KPTI KPTI"
Reddit Link 2024-06-30T14:53Z [--] followers, [--] engagements
"MF SENTRY Phase [--] Trial at [--] sites KPTI KPTI"
Reddit Link 2024-08-27T14:29Z [--] followers, [--] engagements
"Shifted focus to SENTRY (Phase [--] MF) KPTI KPTI"
Reddit Link 2024-09-06T13:39Z [--] followers, [--] engagements
"From OncLive the Head of UCLA Gynecologic Oncology reasons for SLOW SIENDO2 KPTI KPTI"
Reddit Link 2025-02-14T01:43Z [--] followers, [--] engagements
"Myelofibrosis - Historical Ruxolitinib SVR35 - please note only [--] large trials (200+ patients - highlighted below) KPTI KPTI"
Reddit Link 2024-09-12T01:28Z [--] followers, [--] engagements
"Potential Presentation of Phase [--] Myelofibrosis "Initial" Data Could they be wanting to present at ASH [----] KPTI KPTI"
Reddit Link 2024-09-25T20:06Z [----] followers, [--] engagements
"Comparing MF Trials - $MOR MANIFEST-2 and $KPTI SENTRY KPTI KPTI"
Reddit Link 2024-10-22T20:01Z [--] followers, [--] engagements
"HIghbridge Capital with 9.7MM warrants representing 7.2% of all common shares (if exercised)- SEC 13G 10/25/2024 KPTI KPTI"
Reddit Link 2025-02-14T01:43Z [--] followers, [--] engagements
"Dr. DD's thoughts on Q3 [----] Earnings Call - just ENROLL the Trials KPTI KPTI"
Reddit Link 2024-11-05T19:05Z [--] followers, [--] engagements
"Timeline for NASDAQ Compliance KPTI KPTI"
Reddit Link 2024-11-09T20:55Z [----] followers, [--] engagements
"$ABBV buyout of $CERE for Schizophrenia drug fails $8.7BN acquisition cost Abbvie previously pursued Myelofibrosis with Navitoclax KPTI KPTI"
Reddit Link 2024-11-11T21:59Z [--] followers, [--] engagements
"Have a great weekend everybody KPTI KPTI"
Reddit Link 2024-11-23T00:46Z [----] followers, [--] engagements
"Piper Sandler Dec 3rd [----] 11:30 AM EST KPTI KPTI"
Reddit Link 2024-11-25T12:45Z [--] followers, [--] engagements
"$BLUE does [--] for [--] reverse stock split Biotechplays Biotechplays"
Reddit Link 2024-12-05T10:11Z [--] followers, [--] engagements
"Chimerix $XMRX submits for Accelerated Approval (AA) Biotechplays Biotechplays"
Reddit Link 2025-07-23T02:23Z [--] followers, [--] engagements
"J&J doubles down on neurological drugs with $14.6 billion Intra-Cellular deal $JNJ $ITCI Biotechplays Biotechplays"
Reddit Link 2025-01-15T00:17Z [--] followers, [--] engagements
"Dr. DD First half [----] Thoughts - potential catalysts and pitfalls KPTI KPTI"
Reddit Link 2025-02-06T22:59Z [--] followers, [--] engagements
"CEO poll View Poll(https://www.reddit.com/poll/1itk87a) KPTI KPTI"
Reddit Link 2025-02-19T23:38Z [----] followers, [--] engagements
"Karyopharm Therapeutics reverse split [--] to [--]. Thanks Richard KPTI KPTI"
Reddit Link 2025-02-24T22:34Z [----] followers, [--] engagements
"May [--] [----] Q1 [----] Earnings Call KPTI KPTI"
Reddit Link 2025-05-08T22:27Z [--] followers, [--] engagements
"2 more employees hired May 31st [----] KPTI KPTI"
Reddit Link 2025-06-03T03:40Z [--] followers, [--] engagements
"Jefferies Conference Last minute KPTI KPTI"
Reddit Link 2025-06-03T12:21Z [--] followers, [--] engagements
"Why does Richard Paulson keep saying frontline Myelofibrosis is only a billion dollars KPTI KPTI"
Reddit Link 2025-06-06T06:48Z [--] followers, [--] engagements
"Canada going Generic Ozempic A Month Supply of Semaglutide (Weight Loss) for $54 Not Compounded made by Sandoz. Available in [----] [---] days. HIMS HIMS"
Reddit Link 2025-06-15T03:48Z [--] followers, [--] engagements
"If you could get real generic Semaglutide pens for $54/month instead of compounded vials $199 locked in [--] months HimsWeightloss HimsWeightloss"
Reddit Link 2025-06-15T06:20Z [--] followers, [--] engagements
"SVP Michael Method Leaves $KPTI after [--] months to go to $BCYC KPTI KPTI"
Reddit Link 2025-06-27T04:13Z [--] followers, [--] engagements
"Karyopharm Announces Completion of Enrollment in the Phase [--] SENTRY Trial in Myelofibrosis KPTI KPTI"
Reddit Link 2025-12-21T08:28Z [--] followers, [--] engagements
"YOUR THOUGHTS Now that MF Phase [--] trial is fully enrolled there are a few outcomes KPTI KPTI"
Reddit Link 2025-12-21T08:28Z [--] followers, [--] engagements
"Sanofi To Acquire Kadmon ($KDMN) at $9.50 per share Biotechplays Biotechplays"
Reddit Link 2025-07-23T22:03Z [--] followers, [--] engagements
"Clovis Oncology ($CLVS) Update & Hubris with Burnrate Biotechplays Biotechplays"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"Options for December Expire 12/17/21 - Shorts want the price to drop and why it's dropped recently KPTI KPTI"
Reddit Link 2021-12-17T00:49Z [--] followers, [--] engagements
"The ULTIMATE Guide to SIENDO & Endometrial Cancer + Stock Price effects KPTI KPTI"
Reddit Link 2024-12-01T09:16Z [--] followers, [---] engagements
"Dr. DD's quick thoughts post SIENDO Regulatory Update KPTI KPTI"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"Myovant Sciences ($MYOV) Shares Drop 20% After FDA Notice for Myfembree Biotechplays Biotechplays"
Reddit Link 2024-12-05T17:42Z [--] followers, [--] engagements
"Amphista Therapeutics makes strategic collaboration with Merck ($MRK) and Bristol Myers Squibb ($BMY) for Targeted Protein Degradation Therapeutics for up to $2.25BN Biotechplays Biotechplays"
Reddit Link 2022-05-05T14:00Z [--] followers, [--] engagements
"Dr. DD's Quick Thoughts on $KPTI Karyopharm Earnings in Q1 [----] KPTI KPTI"
Reddit Link 2025-03-25T18:20Z [--] followers, [--] engagements
"Pfizer ($PFE) to Acquire Biohaven Pharmaceuticals ($BHVN) - Stock up 70%+ pre-market Biotechplays Biotechplays"
Reddit Link 2024-11-24T08:25Z [--] followers, [---] engagements
"Tsunami Hypothesis #TsunamiHypothesis KPTI KPTI"
Reddit Link 2025-07-25T19:32Z [--] followers, [--] engagements
"Dr. DD's thoughts on Q2 [----] Earnings Call KPTI KPTI"
Reddit Link 2024-10-23T02:19Z [--] followers, [---] engagements
"Three's a company KPTI KPTI"
Reddit Link 2025-07-25T12:35Z [--] followers, [---] engagements
"Dr. DD's thoughts on Phase [--] Selinexor and Jakafi Combo in newly diagnosed Myelofibrosis ASH [----] update KPTI KPTI"
Reddit Link 2026-01-08T10:41Z [--] followers, [--] engagements
"Doctor DD's thoughts on $KPTI Post Raise KPTI KPTI"
Reddit Link 2023-09-15T03:11Z [--] followers, [----] engagements
"Hostile Takeover of the Board coming Rubric Capital buying and things are getting interesting KPTI KPTI"
Reddit Link 2024-10-23T02:19Z [--] followers, [--] engagements
"Karyopharm has no exposure to Silicon Valley Bank ($KPTI $SIVB) KPTI KPTI"
Reddit Link 2024-10-27T11:49Z [--] followers, [--] engagements
"Dr. DD's quick Barclays Notes KPTI KPTI"
Reddit Link 2023-10-27T16:33Z [--] followers, [----] engagements
"Dr. DD Going to be meme'in on twitter about the dilution all week please make sure to vote with your values and don't forget to vote Likes and Retweets appreciated to try and spread the word KPTI KPTI"
Reddit Link 2023-04-09T01:10Z [--] followers, [---] engagements
"Dr. DD's Myelofibrosis Hands down the BIGGEST SHOT on goal left - Competition Status and Catalysts for Second Line MF KPTI KPTI"
Reddit Link 2023-10-27T00:35Z [--] followers, [----] engagements
"Hiring Continues - New SVP for Global Medical and Scientific Affairs Amama Sadiq MD MPH - granted [------] RSUs over [--] years KPTI KPTI"
Reddit Link 2023-10-02T02:35Z [--] followers, [---] engagements
"Dr. DD Letter 006: How to use AI as a tool for Stock Research Biotechplays Biotechplays"
Reddit Link 2023-10-24T12:07Z [--] followers, [----] engagements
"$IMGN earnings Q2 in Ovarian a Comparison for future $KPTI in Endometrial KPTI KPTI"
Reddit Link 2024-10-22T19:56Z [--] followers, [--] engagements
"Had some people message me guess Im famous CafePharma KPTI KPTI"
Reddit Link 2023-09-12T05:30Z [--] followers, [---] engagements
"New Endometrial Cancer VP Clinical Development Medical Lead KPTI KPTI"
Reddit Link 2024-11-24T12:58Z [--] followers, [--] engagements
"Management Primer on Short Psychology Game Theory KPTI KPTI"
Reddit Link 2024-12-01T05:00Z [--] followers, [----] engagements
"Dr. DD Morphosys $MOR wants you to take both pills Biotechplays Biotechplays"
Reddit Link 2023-11-21T07:23Z [--] followers, [---] engagements
"$ABBV buys $IMGN for $10Bn KPTI KPTI"
Reddit Link 2024-10-22T19:56Z [--] followers, [--] engagements
"Abbvie $ABBV buys $IMGN for $10Bn [--] percent premium to last close Biotechplays Biotechplays"
Reddit Link 2024-10-22T19:56Z [--] followers, [--] engagements
"Another ESGO Presentation mentions Selinexor in changing landscape of Endometrial Cancer KPTI KPTI"
Reddit Link 2024-12-25T14:49Z [--] followers, [--] engagements
"LinkedIn Open Letter to Chairman of the Board Barry Greene $KPTI $SAGE KPTI KPTI"
Reddit Link 2024-10-22T20:20Z [--] followers, [--] engagements
"Dr. DD's notes on $KPTI Q1 [----] - Debt Refinancing Quarter KPTI KPTI"
Reddit Link 2024-05-08T22:38Z [--] followers, [--] engagements
"6:41 A CEO out of his depth KPTI KPTI"
Reddit Link 2024-05-29T17:42Z [--] followers, [--] engagements
"Board Member Deepika has been selling a LOT of her shares Petition for Replacement Many on this board have more shares than that. Rubric Capital moved to kick her off of $MREO (she ended up staying) but need someone with institutional contacts KPTI KPTI"
Reddit Link 2024-12-01T06:56Z [--] followers, [--] engagements
"Karyopharm CEO Richard Paulson took over a company worth $1BN. It is now about to be removed from Russell [----] under his leadership KPTI KPTI"
Reddit Link 2024-10-22T20:20Z [--] followers, [--] engagements
"Apple Tree Partners discussion KPTI KPTI"
Reddit Link 2024-06-30T17:00Z [--] followers, [--] engagements
"NCCN discussion KPTI KPTI"
Reddit Link 2025-03-31T11:20Z [--] followers, [--] engagements
"10 Key Statistical Concepts for Biotech Investors Biotechplays Biotechplays"
Reddit Link 2024-09-16T17:59Z [--] followers, [---] engagements
"SENTRY Phase [--] MF Update KPTI KPTI"
Reddit Link 2024-11-01T02:11Z [--] followers, [--] engagements
"$BBIO Attruby (acoramidis) a Near Complete TTR Stabilizer (90%) approved by FDA to Reduce Cardiovascular Death and Cardiovascular-related Hospitalization in ATTR-CM Patients Biotechplays Biotechplays"
Reddit Link 2024-11-24T12:10Z [--] followers, [--] engagements
"$PSTX Poseidon Therapeutics bought out by Roche Biotechplays Biotechplays"
Reddit Link 2024-11-26T09:12Z [--] followers, [--] engagements
"FDA doesn't typically meet too much around Christmas. Possible to hear back about this sooner Phase [--] MM regulatory feedback KPTI KPTI"
Reddit Link 2024-11-27T03:13Z [--] followers, [--] engagements
"$BLUE which has Karyopharm CEO Richard Paulson as a board member being investigated by FDA KPTI KPTI"
Reddit Link 2024-11-28T08:33Z [--] followers, [--] engagements
"Please read $KPTI SEC Filing for 400MM Additional Shares and Reverse Split Vote from CEO Richard Paulson KPTI KPTI"
Reddit Link 2024-12-06T12:19Z [--] followers, [--] engagements
"$EWTX Phase [--] data in Becker Muscular Dystrophy Biotechplays Biotechplays"
Reddit Link 2024-12-16T11:35Z [--] followers, [--] engagements
"Chairman Barry Greene at $KPTI selling $SAGE where he is CEO for cheap to $BIIB Biogen after offer KPTI KPTI"
Reddit Link 2025-01-11T04:09Z [--] followers, [--] engagements
"Merck $MRK Keytruda sales significantly increased. MGMT specifically mentioned Endometrial Cancer multiple times (see below) KPTI KPTI"
Reddit Link 2025-02-14T19:43Z [--] followers, [--] engagements
"Dr. DD's Thoughts on $KPTI 4th Quarter Earnings Call - Get to Work KPTI KPTI"
Reddit Link 2025-02-19T21:37Z [--] followers, [--] engagements
"Please like and retweet if you want to ask Chairman Barry Greene to step down KPTI KPTI"
Reddit Link 2025-02-24T22:54Z [--] followers, [--] engagements
"The Karyopharm Board just awarded [-----] shares was valued $159000 and [-----] options to CEO Richard Paulson. Since May [--] [----] the stock is down 95%. KPTI KPTI"
Reddit Link 2025-03-05T04:42Z [--] followers, [--] engagements
"CEO Richard Paulson could stop the bleeding at any time but he won't KPTI KPTI"
Reddit Link 2025-03-27T17:37Z [--] followers, [--] engagements
"XPORT-MF-044 Phase [--] MF low platelets - Slide removed between Q4 [----] and Q1 [----]. In Q3 [----] stated preliminary data in [----] / early [----] KPTI KPTI"
Reddit Link 2025-05-22T00:25Z [--] followers, [--] engagements
"Myelofibrosis Update via Corporate Slide Deck June [--] [----] and Other Agent Comparisons KPTI KPTI"
Reddit Link 2025-06-10T05:46Z [--] followers, [--] engagements
"Open Letter to CEO Richard Paulson years ago. KPTI KPTI"
Reddit Link 2025-07-02T05:41Z [--] followers, [--] engagements
"Someone is accumulating on low volume from $32MC low up 80% KPTI KPTI"
Reddit Link 2025-08-20T18:19Z [--] followers, [--] engagements
"Market cap $64.69MM after 18% gain today KPTI KPTI"
Reddit Link 2025-08-26T21:05Z [--] followers, [--] engagements
"Down to the wire KPTI KPTI"
Reddit Link 2025-09-24T19:07Z [--] followers, [--] engagements
"Healthcare Royalty KPTI KPTI"
Reddit Link 2025-11-11T06:23Z [--] followers, [--] engagements
"Runway thoughts KPTI KPTI"
Reddit Link 2025-10-20T19:49Z [--] followers, [--] engagements
"Dr. DD's thoughts on Q3 [----] Earnings Call KPTI KPTI"
Reddit Link 2025-11-04T12:02Z [--] followers, [--] engagements
"Clovis ($CLVS) Oncology: A Case Study of Hubris Biotechplays Biotechplays"
Reddit Link 2024-12-01T09:16Z [--] followers, [---] engagements
"Karyopharm ($KPTI) The Biggest Turnaround Opportunity in Biotech by DDD Biotechplays Biotechplays"
Reddit Link 2024-12-01T09:16Z [--] followers, [---] engagements
"Cortexyme ($CRTX) GAIN Trial to make or break the Stock (Q42021) by DDD Biotechplays Biotechplays"
Reddit Link 2024-11-07T18:25Z [--] followers, [---] engagements
"Cortexyme ($CRTX) GAIN Trial to make or break the Stock (Q42021) by DDD FluentInFinance FluentInFinance"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"Letter 002: Discerning types of Biotech Plays Biotechplays Biotechplays"
Reddit Link 2024-10-23T03:56Z [--] followers, [---] engagements
"Letter 002: Discerning types of Biotech Plays FluentInFinance FluentInFinance"
Reddit Link 2024-10-23T03:56Z [--] followers, [--] engagements
"Dr. Due Diligence or How I Learned to Stop Worrying and Love $KPTI Biotechplays Biotechplays"
Reddit Link 2024-11-29T17:08Z [--] followers, [---] engagements
"Oncolytics Biotech ($ONCY) One Piece Away from Being a Great Company by DDD Biotechplays Biotechplays"
Reddit Link 2024-12-01T09:16Z [--] followers, [----] engagements
"Letter 004: Biotech Venture Capital Trends and How it Impacts your Investments Biotechplays Biotechplays"
Reddit Link 2024-12-01T09:16Z [--] followers, [---] engagements
"Karyopharm ($KPTI) Bull & Bear Investment Thesis KPTI KPTI"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"Karyopharm ($KPTI) Bull & Bear Investment Thesis FluentInFinance FluentInFinance"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"Letter 005: Biotech Buckets stocks stocks"
Reddit Link 2024-12-01T09:16Z [--] followers, [---] engagements
"Letter 005: Biotech Buckets by Dr. DD FluentInFinance FluentInFinance"
Reddit Link 2021-09-24T14:00Z [--] followers, [--] engagements
"Letter 005: Biotech Buckets by Dr. DD Biotechplays Biotechplays"
Reddit Link 2024-12-01T09:16Z [--] followers, [---] engagements
"Board Activity - Removal of Mikael Dolsten MD PhD & Addition of Peter K Honig MD MPH KPTI KPTI"
Reddit Link 2025-01-07T22:43Z [--] followers, [---] engagements
"FDA grants Calliditas Therapeutics ($CALT) Accelerated Approval of TARPEYO (budesonide) to Reduce Proteinuria in IgA Nephropathy Biotechplays Biotechplays"
Reddit Link 2026-01-24T01:09Z [--] followers, [--] engagements
"Regeneron to Acquire Checkmate Pharmaceuticals and Its Investigational Immune Activator for Potential Use in Multiple Tumor Types ($250MM) Biotechplays Biotechplays"
Reddit Link 2026-01-24T02:24Z [--] followers, [--] engagements
"$425MM Market Cap today $KPTI $100MM Revenue last year from US Alone KPTI KPTI"
Reddit Link 2025-08-08T19:39Z [--] followers, [--] engagements
"Director Deepika Pakianathan and VC investor sold 538K+ shares still owns 5368MM Shares of $KPTI KPTI KPTI"
Reddit Link 2025-12-08T22:51Z [--] followers, [--] engagements
"Investor Relations doesn't have it listed but CEO RP speaking at Longwood (moderated by Chen Schor - board member) - 9/21/2022 at 9:50 AM EST - more information in comments KPTI KPTI"
Reddit Link 2022-09-20T22:03Z [--] followers, [---] engagements
"MDS - quick update since VP Medical Strategy - MDS Q3 [----] KPTI KPTI"
Reddit Link 2024-12-01T09:16Z [--] followers, [--] engagements
"Clovis Oncology ($CLVS) on earnings call today - we will run out of cash in January [----] (2 months until bankruptcy- shares slide to $0.27 - 71%+ loss in one day Biotechplays Biotechplays"
Reddit Link 2024-10-22T23:19Z [--] followers, [--] engagements
"Doctor DD's thoughts on $KPTI Post Raise Thoughts post raise and ASH (written December 2022) Pros: Company currently has about $300MM cash Company is valued at about $300MM The Senior Convertible Notes (debt) are due 06/2025 I keep hearing binary for MF November Trial - but to be honest I do not see it as binary. This is not a preclinical biotech it is a commercial biotech. The company has an approved agent that will likely bring in $160MM in [----]. This number I believe will grow not diminish. Hopefully they can bring in $200MM in [----]. Additionally for MM agents knowing who will respond is"
Reddit Link 2023-01-08T04:25Z [----] followers, [--] engagements
"Karyopharm has no exposure to Silicon Valley Bank ($KPTI $SIVB)"
Reddit Link 2023-03-11T21:56Z [--] followers, [--] engagements
"New Karyopharm VP President of Quality Hassan Ansari (another AbbVie Hire)"
Reddit Link 2023-04-06T01:50Z [----] followers, [--] engagements
"Dr. DD's Myelofibrosis Hands down the BIGGEST SHOT on goal left - Competition Status and Catalysts for Second Line MF I wrote up quite a bit when I recommended $SRRA last year(https://www.reddit.com/r/Biotechplays/comments/tq8rse/sierra_oncology_srra_myelofibrosis_disease_state/) before their $1.9 Billion buyout by $GSK(https://www.reuters.com/business/healthcare-pharmaceuticals/gsk-buy-sierra-oncology-19-billion-2022-04-13/). # For ease - the important overview of Myelofibrosis from that write-up Myelofibrosis Overview: Myelofibrosis is a terrible rare bone cancer. Im going to give you a"
Reddit Link 2023-04-12T16:03Z [--] followers, [--] engagements
"Dr. DD AACR Frontline Myelofibrosis Phase [--] Full Patient Readout 4/18/2023 - Biggest Opportunity for the Company but does the company have enough time # Third Time's a Charm I saw everyone tweeting and giving their thoughts immediately after the press release. I wanted to listen to the call before I made any snap judgements. I've now listened three times to try and get the deepest and hidden insights. Read below and tell me what you think # Tea Leaves from China (Antengene) drank at the City of Hope My reading of the tea leaves was correct so that's a huge weight off my shoulders. The"
Reddit Link 2023-04-19T01:51Z [----] followers, [--] engagements
"Dr. DD Letter 006: How to use AI as a tool for Stock Research To Those Who Wish to learn I feel like I may be giving away a secret. but. here it goes. Earlier today I had a twitter conversation(https://twitter.com/sentivcapital/status/1663230898702106634) about AI in regards to potential for future impact on stocks. I received a lot of DMs and to be honest I've missed posting in r/Biotechplays and thought I'd write up a little how to guide. First off if you're reading this in the future most of this will be outdated. Focus less on the details and more on the framework / thinking. Secondly I"
Reddit Link 2023-05-29T23:41Z [----] followers, [--] engagements
"Dr. DD $MOR Morphosys MEGATHREAD - includes updated thoughts on $KPTI in Myelofibrosis"
Reddit Link 2023-06-06T21:13Z [----] followers, [--] engagements
"State Street Corporation SEC 13G - what it means 👇🏽"
Reddit Link 2023-07-10T18:51Z [----] followers, [--] engagements
"Open Letter to $KPTI CEO Richard Paulson To Karyopharm Therapeutics CEO Richard Paulson I write to you today because I want you to strongly consider risk aversion. When you see my writings how does it make you feel If it causes uneasiness that is your intuition speaking to you. I only tell what I believe to be the absolute truth from my perspective. Do you think there is a reason why so many people including Karyopharm Therapeutics employees read my writing Does it resonate with them When I post that the stock price has gone down from $9.55 to $1.60 under your leadership that probably doesnt"
Reddit Link 2023-07-17T06:54Z [----] followers, [--] engagements
"$MOR $KPTI and Investment Philosophy Megathread with note of appreciation - Dr. DD"
Reddit Link 2023-07-18T02:12Z [----] followers, [--] engagements
"$GILD agent Magrolimab (CD47) bought from FortySeven for $4.9BN - Phase [--] Trial in MDS High Risk Discontinued. - Competitor to $KPTI Eltanexor"
Reddit Link 2023-07-22T04:33Z [----] followers, [--] engagements
"Dr. DD's Thoughts on ASCO Plenary SIENDO1 Update July 2023"
Reddit Link 2023-07-26T07:43Z [----] followers, [----] engagements
"Dr. DD's Thoughts on Q2 [----] Earnings Call - beginnings of Financial Discipline"
Reddit Link 2023-08-02T15:57Z [----] followers, [----] engagements
"Dr. DD's Thoughts on Karyopharm Therapeutics Department Goals 2023"
Reddit Link 2023-08-09T11:03Z [----] followers, [---] engagements
"Letter 005: Biotech Buckets September 23rd [----] To Those Who Wish to Learn If you dont know what you want you will probably never get it. - Justice Oliver Wendell Holmes Everyone sees biotech investing as largely risky and it is but that is not why you are here(https://www.youtube.com/watchv=4nFNJSIaR7c). There are a million ways for you to lose money and only a few for you to make money. With that being said at the root of biotechs there are essentially [--] categories - New Frontier Platform Copycat Spinoffs and Behemoths with varying potential investment returns. New Frontier: These"
Reddit Link 2021-09-24T01:18Z [----] followers, [--] engagements
"Letter 005: Biotech Buckets by Dr. DD September 24th [----] DoctorDueDiligence(https://docs.google.com/forms/d/e/1FAIpQLSfaW9CrhylAMyHwsT36VSmEH9cF4cZmnq_wCKkN7stbZxlZKg/viewformusp=sf_link) To Those Who Wish to Learn If you dont know what you want you will probably never get it. - Justice Oliver Wendell Holmes Everyone sees biotech investing as largely risky and it is but that is not why you are here(https://www.youtube.com/watchv=4nFNJSIaR7c). There are a million ways for you to lose money and only a few for you to make money. With that being said at the root of biotechs there are"
Reddit Link 2021-09-24T14:00Z [----] followers, [--] engagements
"Dr. DD SVB Quick Feedback February [--] [----] # Sohanya Chang was the best presenter today * Had adequate but tough questions and had smart answers - Community Oncology is defensible and likely not to get T-cell therapy there. * Seems more confident than earlier last year * Fleshed out Xpovio pre and post Car-T benefits * While the low end of revenue projections is static (same as 2022) hopefully they under promise and over deliver. MM is a slow building disease state area. Sales specialists usually do better over time (relationship knowledge disease state). Here's to [----] # Mike Mason * I don't"
Reddit Link 2023-02-17T12:01Z [----] followers, [--] engagements
"Karyopharm Announces Updated Selinexor Data in Patients with Treatment-Nave Myelofibrosis to be Presented at AACR 2023"
Reddit Link 2023-03-15T00:11Z [----] followers, [---] engagements
"Dr. DD Is Eltanexor a Dark Horse MDS Interim Data coming soon The deeper I dive the more I find out. I originally expected the Interim Analysis of [--] patients (expected Q2 2023) was a toss-up. The more I go back and look at older posters and publications the more I think we might have a dark horse. # What we know so far * Second Generation XPO1 Inhibitor * Animal models have shown that there is less weight loss than selinexor = hypothesized it does not cross CNS as much = lower side effects * Has been dosed much more frequently in humans without significant increase in ADEs (caveat -"
Reddit Link 2023-04-01T00:19Z [----] followers, [--] engagements
"Poll What do you think the SVR35 will be of the [--] patient update at AACR 2023"
Reddit Link 2023-04-08T01:01Z [----] followers, [---] engagements
"Dr. DD Poll on $KPTI CEO Richard Paulson KPTI KPTI"
Reddit Link 2023-04-10T23:58Z [----] followers, [--] engagements
"Dr. DD Twitter Thread on my thoughts on Shorts and MF before AACR Poster - I'M NOT LEAVING 🤣"
Reddit Link 2023-04-13T14:51Z [--] followers, [---] engagements
"An Open Letter to the Board"
Reddit Link 2023-05-05T02:20Z [----] followers, [----] engagements
"Meme Theme Vote KPTI KPTI"
Reddit Link 2023-05-09T02:17Z [----] followers, [--] engagements
"How to Stem the Bleeding of $KPTI - The Answers Right now with no near term catalysts and likely dilution coming up Management must act. But how can you act when you have no trial readouts and you just lowered guidance If you are leading a company and you believe it to be undervalued Buy the stock. This is something that multiple c-suite (and Board) could do and it would show confidence that the stock is undervalued. The more bought the more confidence the more the stock moves. This would be an immediate move and if it goes up high enough could dilute at that point if need be. I"
Reddit Link 2023-05-14T22:47Z [----] followers, [---] engagements
"Flurry of Form 4s for Board of Directors (SEC Form 4s 5/25/2023)"
Reddit Link 2023-05-25T21:16Z [----] followers, [---] engagements
"McDreamy Charity sponsored by $KPTI (presenting sponsor much more then even Amgen Spent at $100000) SVP(s) and C-suite headed to Main to drink with Patrick Dempsey"
Reddit Link 2023-06-30T21:46Z [----] followers, [---] engagements
"My Most Viewed LinkedIn Post Ever - even current and former $KPTI high level employees are liking. #FinancialDiscipline #McDreamy Asking Lead $KPTI Director Barry Greene to evaluate Financial Spending and Discipline after hyperlocal Patrick Dempsey focused Charity Spending to be Presenting Sponsor"
Reddit Link 2023-07-05T19:37Z [----] followers, [---] engagements
"$GILD agent Magrolimab (CD47) bought from FortySeven for $4.9BN - Phase [--] Trial in MDS High Risk Discontinued. - Competitor to $KPTI Eltanexor"
Reddit Link 2023-07-24T10:37Z [----] followers, [----] engagements
"Breaking Bad Dr. DD Crossover $KPTI Meme KPTI KPTI"
Reddit Link 2023-08-27T12:47Z [----] followers, [---] engagements
"Letter 007: On the Nature of Value in Biotech To Those Who Wish to Learn If the market is efficient then all companies are accurately priced. If they are not why When a buyout happens in biotech is there a premium If there is a premium then is the market truly efficient It means that there was one or more companies that strongly believe that the biotech is undervalued. Biotech compared to other areas has a higher premium during buyout. It is not unusual to see 100% premium. This means that biotech in general is more affected by the perception rather than the true value. Why [--]. Consumer"
Reddit Link 2023-08-30T12:32Z [----] followers, [----] engagements
"Comments on what Management can do to help stock price $KPTI"
Reddit Link 2023-09-07T17:22Z [----] followers, [---] engagements
"Dr. DD's Thoughts on Karyopharm $KPTI September [----] Investor Calls . KPTI KPTI"
Reddit Link 2023-09-14T22:55Z [----] followers, [--] engagements
"DoctorDueDiligence on X In a widely expected move momelotinib was approved in an unexpected move super broad label $GSK $SRRA #FDA Myelofibrosis KPTI KPTI"
Reddit Link 2023-09-15T22:07Z [--] followers, [--] engagements
"New Board Member Zhen Su MD MBA (CEO Marengo Therapeutics + loves Apple Tree Partners) giving two talks recently (details in body)"
Reddit Link 2023-09-18T23:55Z [----] followers, [---] engagements
"Doctor DueDiligence on LinkedIn: SIENDO2 needs more SITES 51/85 Challenge and BANGING THE DRUM"
Reddit Link 2023-09-20T00:31Z [----] followers, [---] engagements
"The drum beats on - new position created [--] day after for Site Recruitment - Senior Manager Site Relationship & Recruitment Lead"
Reddit Link 2023-09-22T05:49Z [----] followers, [---] engagements
"20th IMS Abstracts - [--] Abstracts Multiple Myeloma"
Reddit Link 2023-09-30T21:12Z [----] followers, [--] engagements
"Senior Manager Site Relationship & Recruitment Lead - job tips for $KPTI"
Reddit Link 2023-10-16T19:46Z [----] followers, [---] engagements
"The 9th Board Member - Zhen Su MBA MD"
Reddit Link 2023-10-17T03:45Z [----] followers, [---] engagements
"News High Risk MDS study + Eltanexor Guidance"
Reddit Link 2023-10-18T00:19Z [----] followers, [---] engagements
"LinkedIn Letter to $KPTI Chairman Barry Greene as Stock Price hits all time low - $0.80 KPTI KPTI"
Reddit Link 2023-10-25T23:11Z [----] followers, [--] engagements
"Impacting T-cell fitness in multiple myeloma: potential roles for selinexor and XPO1 inhibitors"
Reddit Link 2023-10-26T20:38Z [--] followers, [---] engagements
"$KPTI Earnings"
Reddit Link 2023-11-01T01:13Z [----] followers, [--] engagements
"Society for Immunotherapy of Cancer (SITC) on LinkedIn: #biotech #io - Zhen Su MD MBA in NYC KPTI KPTI"
Reddit Link 2023-11-01T22:10Z [----] followers, [--] engagements
"Q3 Earnings Call - post your thoughts KPTI KPTI"
Reddit Link 2023-11-02T06:32Z [----] followers, [--] engagements
"Dr. DDs Thoughts on $KPTI Q3 [----] Earning Call"
Reddit Link 2023-11-03T06:24Z [----] followers, [----] engagements
"Well I know the stock is down near [--] cents but on the bright side remember when $KPTI was the official presenting partner for the McDreamy charity Hes now Peoples Sexiest Man Alive 🤣"
Reddit Link 2023-11-08T19:13Z [----] followers, [---] engagements
"A Letter of Appreciation"
Reddit Link 2023-11-13T11:06Z [----] followers, [---] engagements
"Positives for End of Year [----] $KPTI Wider appreciation for T cell fitness https://www.reddit.com/r/KPTI/s/ICY7k90sbj This is an area of research in Multiple Myeloma but basically MM is a non curable disease state. The immune system is highly important for cancer and cancer growth. Older patients have worse immune systems so that is why they generally have higher incidence rates of cancer. Many therapies focus on using the immune system this can lead to burnout. Other therapies directly hurt fast growing cells like T cells - these are chemotherapeutic in nature. There is a deep growing"
Reddit Link 2023-11-14T10:06Z [----] followers, [----] engagements
"Apple Tree Partners - the 9th Board Member Zhen Su Michael Kauffman Barry Greene"
Reddit Link 2023-11-15T09:36Z [----] followers, [---] engagements
"MEME Some Men just want to See the World Burn"
Reddit Link 2023-11-19T06:39Z [----] followers, [---] engagements
"Posting lots of $KPTI memes today :)"
Reddit Link 2023-11-24T15:06Z [----] followers, [---] engagements
"Need a strong ASH 2023"
Reddit Link 2023-11-26T04:28Z [----] followers, [---] engagements
"SIENDO2 life calculation cost for delays (oversimplified)"
Reddit Link 2023-11-28T14:45Z [----] followers, [---] engagements
"Roche to buy Obesity Biotech Carmot Therapeutics for $2.7BN upfront and potential additional $400MM"
Reddit Link 2023-12-04T06:44Z [----] followers, [----] engagements
"Happy Holidays"
Reddit Link 2023-12-08T06:01Z [----] followers, [---] engagements
"$KPTI Post ASH data desert what I would do if I was management - Leadership for Execution needed I think if the leadership doesn't take action it is very possible a reverse share occurs if it stays below $1. By action (NFA what I would do personally): Convert some of salary to equity or buy a large buy on open market Push SIENDO2. This means trial sites and enrollment. Given the likely power you (if you execute) get this to read out quicker. Myelofibrosis I think won't read out by estimated timeline. [--] sites What is going on with Clin Ops JPM needs to be executed well. You need to generate"
Reddit Link 2023-12-10T03:14Z [----] followers, [--] engagements
"What do you want to hear from $KPTI Management at JPM I'd love to hear *color on number of SIENDO2 patients enrolled and projected full enrollment *MDS Guidance *CCO either increasing sales or getting out of the way (assuming Q4 announced) *Cost cutting *MF update (Phase [--] and 3) *Up to date site count of all trials *Potentially seeking sale of company or ATP involvement and update *Form 4s of retail buying by management (NFA) *Repeat NCCN category [--] update and provide color on T cell fitness *have another top call with key KOLs for SIENDO1 data planned and or announce FDA sNDA if when OS"
Reddit Link 2024-01-03T08:33Z [----] followers, [--] engagements
"Need a TEAM member to show up and get costs down. Need: care about stock can use excel persuasive Vince Vaughn was not available KPTI KPTI"
Reddit Link 2024-01-24T08:09Z [----] followers, [--] engagements
"$1 Meme Team Hot TEAM Summer 🔥 How good was Joaquin in this though KPTI KPTI"
Reddit Link 2024-02-03T13:59Z [----] followers, [--] engagements
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/creator/reddit::DoctorDueDiligence