Upstream Bio, Inc. (UPB)

Upstream Bio's stock plummets over 30% after mixed Phase [--] trial results for severe asthma drug Verekitug, sparking investor concern and a sharp sell-off.

About Upstream Bio, Inc.

Upstream Bio, Inc. is a biotechnology company focused on developing treatments for severe conditions.
Upstream Bio, Inc. uses the ticker $UPB for trading. Listed in the Stocks category.

Insights

Upstream Bio, Inc. (UPB) mentions hit [---] which is 1074% higher than it's daily average.
Upstream Bio, Inc. (UPB) mentions near a 52-week high at [---].
Upstream Bio, Inc. (UPB) creators hit [---] which is 764% higher than it's daily average.
Upstream Bio, Inc. (UPB) social dominance hit [------] which is 628% higher than it's daily average.
Upstream Bio, Inc. (UPB) trading volume is up 571.73% from the previous month.
Upstream Bio, Inc. (UPB) social dominance is up 1295.65% from the previous [--] months.
Upstream Bio, Inc. (UPB) creators is up 145.28% from the previous week.
Upstream Bio, Inc. (UPB) engagements is up 331.79% from the previous week.
Upstream Bio, Inc. (UPB) mentions is up 99.64% from the previous week.
Upstream Bio, Inc. (UPB) posts created is up 904.4% from the previous year.
Upstream Bio, Inc. Mentions hit a 52-Week high of [---] for the day
Upstream Bio, Inc. Mentions hit an all time of [---] for the day
Upstream Bio, Inc. Galaxy Score™ hit a 52-Week high of [--] for the hour
Upstream Bio, Inc. Galaxy Score™ hit an all time of [--] for the hour
Upstream Bio, Inc. Price hit a 52-Week high of $32.80 for the hour
Upstream Bio, Inc. Price hit an all time of $32.80 for the hour

Price: $8.80

Price 24-Hour Time-Series Raw Data
The stock price has experienced a significant decline, dropping over 30% in the last [--] hours, following the release of Phase [--] trial data for their severe asthma drug, Verekitug. Mixed efficacy results appear to have spooked investors, leading to a sharp sell-off.

24-Hour: -31.05% 7-Day: -65.59% 30-Day: -71.77%

1-Year High: $32.60 on 2026-01-13
1-Year Low: $8.80 on 2026-02-13

AltRank: [---]

AltRank Line Chart
AltRank 24-Hour Time-Series Raw Data
Upstream Bio, Inc. (UPB) is currently AltRank #452 based on combined combined social and market metrics Daily Average: [-----]
[--] Week: [---] [----]
1-Year High: [-----] on 2026-02-05
1-Year Low: [---] on 2026-01-25

Galaxy Score: [-----]

Galaxy Score Line Chart
Galaxy Score 24-Hour Time-Series Raw Data
Current Value: [-----]
Daily Average: [--]
[--] Week: [--] [---]
[--] Month: [--] [---]
[--] Months: [--] +11
[--] Year: [--] [---]
1-Year High: [--] on 2026-01-26
1-Year Low: [--] on 2025-10-02

Engagements: [-----] (24h)

Engagements Line Chart
Engagements 24-Hour Time-Series Raw Data
Current Value: [-----]
Daily Average: [-----]
[--] Week: [-------] +332%
[--] Month: [-------] +298%
[--] Months: [-------] +9.10%
[--] Year: [---------] +243%
1-Year High: [-------] on 2025-03-11
1-Year Low: [--] on 2025-05-09

Engagements by network (24h): News: [--] X: [-----] Reddit: [--] YouTube: [--]

Mentions: [---] (24h)

Mentions Line Chart
Mentions 24-Hour Time-Series Raw Data
Current Value: [---]
Daily Average: [--]
[--] Week: [---] +100%
1-Year High: [---] on 2026-02-13
1-Year Low: [--] on 2025-05-09

Mentions by network (24h): News: [--] X: [---] Reddit: [--] YouTube: [--]

Creators: [---] (24h)

Creators Line Chart
Creators 24-Hour Time-Series Raw Data
[---] unique social accounts have posts mentioning Upstream Bio, Inc. (UPB) in the last [--] hours which is up 23% from [---] in the previous [--] hours Daily Average: [--]
[--] Week: [---] +145%
1-Year High: [---] on 2025-06-28
1-Year Low: [--] on 2025-05-09

The most influential creators that mention Upstream Bio, Inc. in the last [--] hours

Creator	Rank	Followers	Posts	Engagements
@BiopharmIQ	[--]	[------]	[--]	[---]
@RiskInhibitor	[--]	[--]	[--]	[---]
@CavalryCologne	[--]	[--]	[--]	[---]
@BPharmCatalyst	[--]	[------]	[--]	[---]
@ahelaahela23	[--]	[--]	[--]	[---]
@BOSSTRADING0	[--]	[-----]	[--]	[---]
@Biotech2k1	[--]	[------]	[--]	[---]
@ElMonoGran42994	[--]	[---]	[--]	[--]
@stocktreats	[--]	[-----]	[--]	[--]
@Investingcom	[--]	[------]	[--]	[--]

Sentiment: 48%

Sentiment Line Chart
Sentiment 24-Hour Time-Series Raw Data
Current Value: 48%
Daily Average: 81%
[--] Week: 50% no change
[--] Month: 35% -8%
[--] Months: 35% -45%
[--] Year: 35% -65%
1-Year High: 100% on 2025-02-17
1-Year Low: 10% on 2026-01-20

Most Supportive Themes:

Creator Engagement: (99%) The number of engagements on posts mentioning $upb has seen a significant increase over the past year, indicating growing community interest and interaction.
Creator Activity: (95%) The number of unique creators posting about $upb has also shown substantial growth over the past year, suggesting a broadening base of influencers discussing the topic.

Most Critical Themes:

Recent Engagement Dip: (-71%) While yearly trends are positive, recent 24-hour engagements are down significantly compared to the daily average, suggesting a temporary lull in immediate community buzz.
Mentions Decline: (-71%) The number of mentions has decreased over the past month, which could indicate a slight reduction in overall conversation volume around $upb.

Social Dominance: 0.027%

Social Dominance Line Chart
Social Dominance 24-Hour Time-Series Raw Data
Current Value: 0.027%
Daily Average: 0.00441%
[--] Week: 0.025% +0.019%
[--] Month: 0.032% +0.029%
[--] Months: 0.032% +0.03%
[--] Year: 0.032% +0.029%
1-Year High: 0.049% on 2025-03-11
1-Year Low: 0.0002% on 2025-05-09

Market Dominance: 0.0005386780130073258%

Market Dominance Line Chart
Market Dominance 24-Hour Time-Series Raw Data
Current Value: 0.0005386780130073258%
Daily Average: 0%
1-Year High: 0.00205% on 2026-01-13
1-Year Low: 0.00054% on 2026-02-16

Market Cap: $475,539,601

Market Cap Line Chart
Market Cap 24-Hour Time-Series Raw Data
Current Value: $475,539,601
Daily Average: $1,439,958,615
[--] Week: $475,539,601 -66%
[--] Month: $472,837,671 -72%
1-Year High: $1,761,658,067 on 2026-01-13
1-Year Low: $472,837,671 on 2026-02-13

Top Upstream Bio, Inc. Social Posts

Top posts by engagements in the last [--] hours

Showing a maximum of [--] top social posts without a LunarCrush subscription.

"📉🔻 Top Losers 🔻📉Last Week $AIM $OBAI $POAS $LIMN $AZI $PLYX $BRTX $AREB $SSKN $UOKA $UPB $LHSW $ANPA $ELPW $PFSA"
X Link @PeterJantsch 2026-02-15T20:05Z [---] followers, [---] engagements

"$UPB The market overreacted. The selloff is overdone. The stock is worth at least $11 in my view. This is gearing up for a massive short squeeze on Tuesday. Shorts will cover and the move up will be violent. $GME $OPEN"
X Link @CavalryCologne 2026-02-15T19:12Z [--] followers, [---] engagements

"🧬 Biotech Weekly News Largest single-day stock moves during the week ending 02/13/26 📈 $EVMN 71% EVO301 Topline data $NKTR 51% REZOLVE-AD Maintenance Data $HUMA 30% New Defense Funding for Blood Vessels $PHIO 24% Positive SMC wrap-up on PH-762 $NVCR 19% FDA Approves Optune Pax for Cancer 📉 $UPB -47% VALIANT Trial Results $MCRB -42% Program and Corporate Updates $CHRS -20% Pricing of Public Offering $1.75/sh $OKYO -19% Pricing of $20M Offering $1.85/sh $RGNX -14% Regulatory Update on RGX-121 BLA See image below. *** AD momentum continues. $NKTR maintenance data + early Ph2a from $EVMN in a"
X Link @BiopharmIQ 2026-02-14T14:02Z 28.9K followers, [----] engagements

"$ONCY reported significant coordinated insider buying across all executive and board levels on February [----] [----]. Purchases between $0.83 and $0.86 per share signal strong confidence at the current price; shares closed up 26%. $IRON $ONCY $PHIO $CHRS $OKYO $EVMN $AIM $ICLR $INTS $UPB See More Biotech Updates👇 https://www.biopharmcatalyst.com/news/2026/disc-iron-22-complete-response-letter-crl-oncolytics-oncy-27-insider-buys https://www.biopharmcatalyst.com/news/2026/disc-iron-22-complete-response-letter-crl-oncolytics-oncy-27-insider-buys"
X Link @BPharmCatalyst 2026-02-13T21:35Z 30.7K followers, [----] engagements

Limited data mode. Full metrics available with subscription: lunarcrush.com/pricing