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gregmushen Avatar Greg Mushen @gregmushen on x 24.2K followers Created: 2025-07-20 13:59:21 UTC

Endogenous cholesterol synthesis is tightly regulated, especially in steroidogenic tissue like testes which mostly use locally synthesized cholesterol.

Steroid hormone production is gated by LH/FSH signaling, not dietary fat intake. No amount of suet will correct the signaling failure.

Men with primary hypogonadism cannot produce testosterone.

Men with secondary hypogonadism have a signaling failure.

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