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@JacobPlieth Avatar @JacobPlieth Jacob Plieth

Jacob Plieth posts on X about $onc, $nrix, $jnj, $tern the most. They currently have XXXXXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours.

Engagements: XXXXX #

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Mentions: XX #

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Followers: XXXXXX #

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Social Influence

Social category influence cryptocurrencies XXXXX% stocks XXXXX% currencies XXXX%

Social topic influence $onc #1, $nrix #3, $jnj #15, $tern #1, $smmt #7, tern #11, $aclx #2, $elvn #1, $azn #37, $lly #81

Top accounts mentioned or mentioned by @apexonco @avidresearch @bymadeleinea @ablt315i @bllphd @drpaulydesantis @s86coffeedev @houndcl @financebully @bananaoncology @stlbiotech @jq1234t @kinatsofrim @hartungingo @hothomaswphelps @biotwit1 @chuminhua432 @charlene_liao @hall8jack @learnbiotech

Top assets mentioned One Cash (ONC) Johnson & Johnson (JNJ) Terns Pharmaceuticals, Inc. Common Stock (TERN) Summit Therapeutics Inc. Common Stock (SMMT) Arcellx, Inc. Common Stock (ACLX) AstraZeneca PLC (AZN) Eli Lilly and Company (LLY) Pfizer, Inc. (PFE) Janux Therapeutics, Inc. Common Stock (JANX) AbbVie Inc (ABBV) Bristol-Myers Squibb Co (BMY) Dawn Protocol (DAWN) Novartis AG (NVS) Regeneron Pharmaceuticals Inc (REGN) Allora (ALLO) BOLT Token (BOLT) Revolution Medicines, Inc. Common Stock (RVMD) Royalty Pharma plc Class A Ordinary Shares (RPRX) Incyte Corporation (INCY) Jazz Pharmaceuticals, Inc. (JAZZ)

Top Social Posts

Top posts by engagements in the last XX hours

"By my calculation $ONC now has an efficacy edge vs $NRIX in BTK degradation. Caveats: small pt numbers X-trial comparison and Nurix might have the safety advantage #ASH25"
X Link 2025-12-08T11:12Z 31.3K followers, 2476 engagements

"$TERN looks like the winner of #ASH25 then +37% yesterday and +600% since November's abstract lift. Funny when I last wrote about it in May it was worth a quarter of $ELVN"
X Link 2025-12-09T09:55Z 31.3K followers, 7320 engagements

"$LLY Jaypirca looks best. up to a point. Via @ApexOnco from #ASH25 $ONC $AZN $JNJ $ABBV $NRIX"
X Link 2025-12-09T12:45Z 31.3K followers, 4057 engagements

"$TERN wins #ASH25 via @ApexOnco - $ELVN $NVS"
X Link 2025-12-09T14:07Z 31.3K followers, 5726 engagements

"If you enjoyed #ASH25 you can catch up on all @ApexOnco coverage including previews here - $TERN $JNJ $LLY $CGEM $ONC $NRIX $PFE $REGN $KURA"
X Link 2025-12-09T14:41Z 31.3K followers, 4099 engagements

"Allogeneic FTW $CLLS $ALLO"
X Link 2023-11-28T17:00Z 31.3K followers, 4642 engagements

"Let's go $LEGN (H/t Umer Raffat)"
X Link 2024-05-13T13:20Z 31.3K followers, 4668 engagements

"Jaypirca shocker XX% crossover in confirmatory Bruin CLL-321 trial - obviously unavoidable and obviously trashes the OS benefit. $LLY toplined it positive for PFS which will surely confirm approval. Via Jeff Sharman #ASH24 $BGNE $ABBV $AZN $JNJ"
X Link 2024-12-09T23:35Z 31.3K followers, 13.3K engagements

"$BGNE -XX% $NRIX +8%. I'm puzzled. #ASH24 data:"
X Link 2024-12-10T15:50Z 31.3K followers, 16.1K engagements

"$BGNE vs $NRIX in BTG degradation. I can't remember the last time I saw two separate datasets yield results that look so similar #ASH24"
X Link 2024-12-10T23:46Z 31.3K followers, 9766 engagements

"Catching up on some #ASCO25 sessions I came across this on dual-payload ADCs from Patricia LoRusso's clinical science symposium"
X Link 2025-06-06T13:09Z 31.3K followers, 6825 engagements

"@DrPaulyDeSantis See $INBX acasunlimab (also to an extent Silverback & $BOLT) & others"
X Link 2025-07-25T08:27Z 31.3K followers, XXX engagements

"Reminder: Akeso Harmoni-A interim OS hazard ratios went from XXXX - XXXX (again no p values or significance thresholds revealed). Final OS HR is likely worse than XXXX. $SMMT Harmoni interim OS HR=0.79 (p=0.057). I don't see how $SMMT p value now magically goes below 0.05"
X Link 2025-08-27T10:33Z 31.3K followers, 5052 engagements

"New players in dual-payload ADCs: Lonza Synaffix & Qurient Therapeutics. CDK7 inhibitor"
X Link 2025-09-25T07:44Z 31.3K followers, 2151 engagements

"Gammadelta T cells FTW $IPN.PA buying Imcheck for EUR350m. Approach seems not dissimilar to the now departed $LVTX"
X Link 2025-10-22T06:12Z 31.3K followers, 11.8K engagements

"$PFE moves its $1.25bn PD-1 x VEGF bispecific bet quickly into pivotal trials with NSCLC & colorectal efforts mirroring $SMMT & $BNTX / $BMY. Via @ApexOnco -"
X Link 2025-11-06T11:12Z 31.3K followers, 5977 engagements

"Well I was wrong about Harmoni-A: OS HR went from XXXX (30% maturity) - XXXX (52% maturity) - XXXX (final analysis). #SITC25 $SMMT Hail Mary for Harmoni which already failed for OS at final analysis appears to be this "tail":"
X Link 2025-11-10T09:09Z 31.3K followers, 2337 engagements

".as such this appears to be the far more important $SMMT disclosure about its global Harmoni study: final OS fail (HR=0.79 p=0.057) but subsequent analysis - HR=0.78 (CI upper bound now XXXX not 1.01) suggesting long-term tail developing"
X Link 2025-11-10T09:21Z 31.3K followers, 4372 engagements

"Does this all matter $SMMT already said it would file on Harmoni anyway and the September OS analysis appears to have been the trigger for this. Now we wait and see"
X Link 2025-11-10T10:27Z 31.3K followers, 2589 engagements

"$DAWN to the rescue $MRSN"
X Link 2025-11-13T11:21Z 31.3K followers, 10.9K engagements

"What has $DAWN seen in $MRSN Via @ApexOnco -"
X Link 2025-11-13T13:32Z 31.3K followers, 3333 engagements

"@s86CoffeeDev @houndcl @financebully @avidresearch @Banana_Oncology $ERAS says ERAS-0015 uses different scaffold vs daraxonrasib. Not sure if that circumvents $RVMD patent"
X Link 2025-11-19T11:17Z 31.3K followers, XXX engagements

"$ZYME becomes more selective in R&D and moves to royalty aggregation & share buybacks. Via @ApexOnco - $RPRX $XOMA"
X Link 2025-11-19T14:38Z 31.3K followers, 2806 engagements

"Just accepted for FDA priorty review. "The treatment was well tolerated and the risks were manageable" so that's all right then $ONC"
X Link 2025-11-26T11:11Z 31.3K followers, 8512 engagements

"If you need some biotech reading over Thanksgiving check out @ApexOnco previews of #ASH25 -- Starts in just over a week $ACLX $ONC $CRVS $TERN $KURA $SNDX $CGEM $INCY"
X Link 2025-11-27T13:37Z 31.3K followers, 5863 engagements

"A year ago we were warning you that $JANX was cherrypicking data. It all seems to be unravelling today stock -50%"
X Link 2025-12-02T14:40Z 31.3K followers, 19.9K engagements

"@STL_Biotech That CRS prophylaxis tidbit might be the most deranged aspect of today's $JANX collapse. Wild"
X Link 2025-12-02T21:33Z 31.3K followers, 1615 engagements

"$JAZZ Ziihera data from Herizon-GEA-01 study coming at #GI26"
X Link 2025-12-03T07:45Z 31.3K followers, 2462 engagements

"$JANX ended -XX% $CTMX -11%. Here's yesterday's take from @ByMadeleineA at @ApexOnco"
X Link 2025-12-03T07:57Z 31.3K followers, 2212 engagements

"So basically since I wrote this in Jan 2024 the $SGN $PFE patent was "revalidated" and it's just been invalidated again"
X Link 2025-12-03T11:21Z 31.3K followers, 4303 engagements

"@avidresearch Be fair though that's actually not saying a lot LOL"
X Link 2025-12-03T17:11Z 31.3K followers, 2249 engagements

"$NRIX +23% surprises me. I thought the #ASH25 data showed $ONC to be better on efficacy (with caveats) albeit worse on safety. My earlier take on @ApexOnco -"
X Link 2025-12-08T15:41Z 31.3K followers, 4841 engagements

"@avidresearch OS even with slightly fugly crossover gives HR=0.46 $JNJ #ASH25 As ever infection risk is very real with CD3-targeting T-cell engagers"
X Link 2025-12-09T13:07Z 31.3K followers, XXX engagements

"@avidresearch Wait until you see $AZN CD8-based T-cell engagers (Perhaps.)"
X Link 2025-12-09T13:11Z 31.3K followers, 1427 engagements

"@jq1234t Hmm I think I might be getting it confused with 35T. Thx"
X Link 2025-12-09T14:00Z 31.3K followers, XXX engagements

"@ablT315I And. here come the sellside notes defending $ACLX"
X Link 2025-12-09T17:14Z 31.3K followers, XXX engagements

"$ELVN vs $TERN: game over #ASH25"
X Link 2025-12-09T11:03Z 31.3K followers, 5330 engagements

"Wow check out the $JNJ Tecvayli survival curves in Majestec-3 #ASH25"
X Link 2025-12-09T13:02Z 31.3K followers, 6516 engagements

"$JNJ Tecvayli (& $LEGN Carvykti) "entering a new era of resetting survival expectations in a cancer historically described as incurable". @ByMadeleineA @ApexOnco from #ASH25 on Majestec-3 $ACLX $BMY"
X Link 2025-12-09T13:05Z 31.3K followers, 5725 engagements

"What a stinker of an #ASH25 for $ACLX -XX% since Nov abstract drop. Inconsequential Immagine-1 update while others making huge strides"
X Link 2025-12-09T17:30Z 31.3K followers, 4991 engagements