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@NoseRubInvest
"@lifeisblank21 more $BMEA context of the denominator "A total of XXX patients received at least one dose of icovamenib and were considered evaluable for the modified intent-to-treat (mITT) population.""
X Link @NoseRubInvest 2025-10-06T20:18Z 1862 followers, 10.7K engagements
"$QURE Can I say something w/o ppl getting mad Isn't it totally crazy placebo beats AMT-130 at the main endpoints they're pointing to to show efficacy Pbo beats both drug arms at 12mo with cUHDRS TFC and NfL. Forget XX% slowing of dz; pbo has XXX% slowing of dz progression"
X Link @NoseRubInvest 2025-10-09T17:07Z 1862 followers, 21.8K engagements
"I think the lesson is to study the insane jedi mind tricks that made FDA allow external control here and the media to celebrate these "results" like crazy $QURE"
X Link @NoseRubInvest 2025-10-09T17:08Z 1862 followers, 4305 engagements
"@pemulisking Yea but I really what to understand how external control is even allowed here. Pbo pts aren't progressing at all and the co argues oh well there's a certain point where pbo pts wouldn't be eligible bc they progress so it would be unethical to go longer $QURE"
X Link @NoseRubInvest 2025-10-09T17:26Z 1861 followers, XXX engagements
"Pbo were eligible for crossover at 12mo and we don't know what happened to those that didn't crossover. It seems kinda funny to approve on just natural history when pbo isn't even matching natural history"
X Link @NoseRubInvest 2025-10-09T17:07Z 1862 followers, 3050 engagements