[GUEST ACCESS MODE: Data is scrambled or limited to provide examples. Make requests using your API key to unlock full data. Check https://lunarcrush.ai/auth for authentication information.]
@AponiaAnalytics
"🦉 Contraindications: Personal/family history of MTC or MEN2 rules out GLP-1 RA use. No routine thyroid monitoring required. FDA cites theoretical cancer risk but no human trial evidence confirms it. #GLP1 #safety $NVO $LLY $AZN $SNY $VKTX $GSK $PFE"
@AponiaAnalytics on X 2025-07-20 21:33:21 UTC 5024 followers, XXX engagements
"$LIXT $THTX $CLRB $OSTX $VRTX $ELAN $OGEN $NVS $FDMT $DYN $NKTR $IMAB $BCAB $INO" @AponiaAnalytics on X 2025-07-03 15:59:06 UTC 5019 followers, XXX engagements
"🦉 XX% of PCOS patients in a survey (n=1700) using GLP-1s reported more predictable periods; XX% had shorter bleeding days. Indicates hormonal impact beyond weight reduction. #GLP1 #PCOS $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 16:00:00 UTC 5028 followers, XXX engagements
"🦉 In REWIND dulaglutide cut cognitive decline risk by 14%. Not dementia-specific but shows neurological effects. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:23:36 UTC 5021 followers, XXX engagements
"🦉 Adverse events were inconsistently reported; no link found between adverse events and post-AOM weight regain. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:09:50 UTC 5020 followers, XXX engagements
"💼Visual demonstration of weight loss and health risk improvement with a dual GIP and GLP-1 receptor agonist $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #obesity #GIP #GLP1" @AponiaAnalytics on X 2025-07-18 14:37:49 UTC 5029 followers, XXX engagements
"🦉 Liraglutide (Victoza Saxenda): daily injection. Semaglutide (Ozempic Wegovy Rybelsus): weekly or oral. Dulaglutide (Trulicity): weekly. All deliver durable GLP-1 signaling for metabolic control. #GLP1 #Tirzepatide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 15:31:18 UTC 5032 followers, XXX engagements
"🦉 Predictors of success: HbA1c X% (aOR: XXX at X months; XXXX at XX months). Impairing factors: age XX (aOR: XXXX and 0.41) and primary care prescriptions (aOR: XXXX at X months). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 18:03:27 UTC 5029 followers, XXX engagements
"Regeneron and Sanofis EoE Study with DUPIXENT: Key Insights for Investors $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:21:16 UTC 5032 followers, XXX engagements
"🦉 GLP-1 drugs may act directly on the brain: receptors are distributed across CNS; possible effects include reducing neuroinflammation. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:24:14 UTC 5021 followers, XXX engagements
"🦉 XX% CSF/serum exenatide concentration in PD suggests limited CNS penetration. Yet motor benefits persisted up to XX weeks. #GLP1 #Parkinsons $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:39:48 UTC 5021 followers, XXX engagements
"Zepbound Market Booming with Obesity Management Demand and GLP-1 Receptor Agonist Innovations 2025-2032 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:23:57 UTC 5030 followers, XXX engagements
"Novo Nordisk's Alhemo Expansion: A Strategic Move in the Hemophilia Market $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:34:55 UTC 5025 followers, XXX engagements
"🦉 Clinical trials: Liraglutide preserved cortical bone mass during weight loss. Systematic review (25 studies): GLP-1RAs increased BMD at lumbar spine/femoral neck in T2DM XX years. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 20:09:57 UTC 5028 followers, XXX engagements
"🦉 Despite efficacy semaglutide discontinuation leads to weight regainSTEP X extension and STEP X confirm relapse within X year. Long-term therapy is necessary. #GLP1 #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 17:21:59 UTC 5028 followers, XXX engagements
"🦉 Optic neuropathy signal: semaglutide tripled NAION risk (HR: 2.81) though meta-analysis showed non-significant results (OR: 1.53). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:30:07 UTC 5020 followers, XXX engagements
"🦉 DA-JC4s BBB influx rate (Ki): XXXXXX L/g-min vs semaglutide: negligible. Acylation improves stability reduces brain permeability. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:40:54 UTC 5032 followers, XXX engagements
"🦉 EVOKE and EVOKE+ trials will test GLP-1 RAs in patients with mild cognitive impairment without diabetesresults expected 2026. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:24:37 UTC 5021 followers, XXX engagements
"🦉 Type X diabetes increases dementia risk by 60%. Both GLP-1 RAs and metformin reduce this risk but GLP-1 RAs appear more effective. #diabetes #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:23:50 UTC 5021 followers, XXX engagements
"Warning issued for 'counterfeit Ozempic' as FDA finds fake drug circulating in US $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:21:01 UTC 5032 followers, XXX engagements
"🦉 In OSCC models semaglutide reduced migration proliferation and viability in a dose-dependent way. GLP-1 receptor protein higher in tumors than in normal tissue. #GLP1 #cancer $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:45:47 UTC 5023 followers, XXX engagements
"🦉 In the study XX RCTs were pooled: X with GLP-1 RAs X placebo-controlled and X active-controlled total n=2466. #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:10:03 UTC 5020 followers, XXX engagements
"$NVDA $PLTR $TSLA $AVGO $EOSE $AMD $MU $OKLO $NBIS $ASML 🌐" @AponiaAnalytics on X 2025-07-27 21:19:27 UTC 5021 followers, XXX engagements
"🦉 Despite lower mortality in GLP-1 RA users (4.8% vs 8.8%) dementia reduction remained significantbias toward underestimation. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:05:05 UTC 5021 followers, XXX engagements
"🦉 Across XX trials GLP-1 drugs reduced inflammation and oxidative stress even when blood sugar control wasnt the main factor. Benefits go beyond diabetes. #GLP1 #inflammation $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:54:36 UTC 5024 followers, XXX engagements
"Weight loss jabs such as Mounjaro linked to lower dementia and stroke risk $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-15 19:30:23 UTC 5021 followers, XXX engagements
"Lillys orforglipron and other key catalysts set to reshape drug landscape $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-12 23:07:52 UTC 5024 followers, XXX engagements
"🦉 GLP-1RAs lowered GI cancer incidence in T2D patients no longer requiring insulin compared to insulin-only users. Suggests GLP-1RAs may neutralize T2D-linked cancer risk. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:45:25 UTC 5029 followers, XXX engagements
"🦉 XX trials included: STEP XX XX HFpEF HFpEF-DM. Intervention: semaglutide XXX mg weekly for 4468 weeks. Study populations ranged from XXX to 1900 participants. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 17:18:36 UTC 5028 followers, XXX engagements
"🦉 Reporter typesION: XX% healthcare professionals; retinal tear: XX% consumer-reported. All ION cases were classified as serious. #GLP1 #stroke $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:16:19 UTC 5030 followers, XXX engagements
"Novo Nordisk loses Wegovy patent fight against generics maker Viatris $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:22:24 UTC 5027 followers, XXX engagements
"🦉 DA-JC4 brain uptake: XXXX% per gram XXXX% reached parenchyma. Semaglutide liraglutide: no measurable influx. Acylation may limit BBB entry. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:20:28 UTC 5025 followers, XXX engagements
"💼Muscle loss from GLP-1 drugs could undermine long-term health $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 19:54:17 UTC 5032 followers, XXX engagements
"🦉 In STEP-HFpEF-DM semaglutide lowered CRP by XX% in obese patients with type X diabetestriple the drop seen with placebo. Inflammation clearly decreased. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:54:19 UTC 5024 followers, XXX engagements
"🦉 XX mg tirzepatide achieved XXXX% weight loss (17.8% placebo-subtracted) at XX weeks in SURMOUNT-1; XX% of SELECT trial participants were nonresponders to semaglutide. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:16:31 UTC 5030 followers, XXX engagements
"🦉 FLOW trial: semaglutide cut kidney complications by XX% (HR: XXXX XX% CI 0.660.88) in diabetic CKD patients. #diabetes #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:27:50 UTC 5018 followers, XXX engagements
"$ABVX $LYEL $CNTB $CRDL $DMAC $REPL X $IMNN $PHVS $MEIP $ALKS 🌐" @AponiaAnalytics on X 2025-07-25 23:14:58 UTC 5023 followers, XXX engagements
"🦉 Alzheimers Society noted stronger dementia risk reduction with GLP-1 RAs in White patients than other ethnic groups. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:24:02 UTC 5021 followers, XXX engagements
"🦉 Tirzepatide activates both GIP and GLP-1 receptors. Early data shows superior glucose and weight loss outcomes vs. semaglutide. Triple agonists targeting GLP-1/GIP/glucagon are under development. #Tirzepatide #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY" @AponiaAnalytics on X 2025-07-20 15:32:32 UTC 5023 followers, XXX engagements
"🦉 Dementia risk in White patients: AHR XXXX (95% CI 0.790.92) for GLP-1 RAs vs metformin. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:02:56 UTC 5021 followers, XXX engagements
"$APLS $ALPMY $OCUL $EYPT $REGN $SRZN $RHHBY $APLS $ALPMY 🌐" @AponiaAnalytics on X 2025-07-10 23:53:50 UTC 5027 followers, XXX engagements
"$VIR $APLM $LLY $ANAB $BHVN $RXRX $VIRX $VIRX $SWTX $KZIA $SLS $NUVL $AGEN $ACRS $CRDF $VRCA $NKTR $KAPA $CYBN $MLYS $ARCT $PROK $ANRO $SPRO $VTYX $MURA $INMB $IMRX $CRDL $ATAI $INMB $ALT $ACIU" @AponiaAnalytics on X 2025-06-15 18:19:07 UTC 5020 followers, 2700 engagements
"🦉 Exendin-4 entered brain X min post-injection. Entry inhibited by exendin-(939) confirming GLP-1 receptormediated uptake. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:40:02 UTC 5030 followers, XXX engagements
"🦉 Alcohol use disorder: semaglutide cut drinking days (: 0.41) and cravings (: 0.39). Real-world: lower hospitalization risk. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:29:41 UTC 5018 followers, XXX engagements
"🦉 Final outcome: observational data consistent with GLP-1 RAs offering stronger neuroprotection than metformin pending trial validation. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:27:20 UTC 5021 followers, XXX engagements
"🦉 Study did not report treatment durations or stratify outcomes by drug subtypelimits precision of comparative conclusions. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:24:26 UTC 5021 followers, XXX engagements
"🦉 In ESSENCE semaglutide resolved MASH in XXXX% vs. XXXX% (ETD: XXXX% XX% CI 21.136.2%) without worsening fibrosis. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:28:19 UTC 5021 followers, XXX engagements
"🦉 XX% of XX participants had type X diabetes; baseline liver fat averaged XXXX% BMI XXXX kg/m; XX% Hispanic ethnicity. #diabetes #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:35:33 UTC 5025 followers, XXX engagements
"🦉 Large-scale study (40k patients): semaglutide reduced periprosthetic infections sepsis and readmissions after knee arthroplasty. Yet increased MI AKI pneumonia also observed. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 20:41:38 UTC 5028 followers, XXX engagements
"$PFSA 🌐 $RAYA $GSIW $OXLC $SLDP $KIDZ $CANG $SQNS $GAME $EAF" @AponiaAnalytics on X 2025-07-21 19:08:38 UTC 5019 followers, XXX engagements
"🦉 Semaglutide reduced tumor volume and liver metastases in a syngeneic breast cancer model. Effect vanished if drug was stopped before tumor cell injection. #GLP1 #cancer $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:44:46 UTC 5024 followers, XXX engagements
"🦉 Liraglutide and semaglutide delay gastric emptying. Tirzepatide mimics this but effect fades. Still dose-escalation preserved delay in T2DM patients unlike constant exposure. #Semaglutide #Tirzepatide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 19:33:51 UTC 5030 followers, XXX engagements
"🦉 Lixisenatide reduced fusiform gyrus activity in obese T2DM patients when exposed to food cues. n = XX randomized study. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:40:15 UTC 5030 followers, XXX engagements
"🦉 Use of SGLT2i lower in women than men (50.2% vs. XXXX% p 0.001). In women with CKD use was XXXX% vs. XXXX% in men (p = 0.04) suggesting a sex-based treatment gap in nephroprotection. #diabetes #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 18:06:05 UTC 5027 followers, XX engagements
"🦉 XX% of participants in STEP trials reported GI disorders with XXX mg semaglutide weekly. Yet on Instagram these AEs were mentioned in X% of postsdespite being the most common reaction. #GLP1 #Semaglutide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 16:16:37 UTC 5028 followers, XX engagements
"🦉 AHR for AD in females: XXXX (95% CI 0.750.89); males: XXXX (95% CI 0.840.97). Greater cognitive protection in women. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:01:45 UTC 5021 followers, XXX engagements
"🦉 Other non-vascular dementias: XXX% with GLP-1 RAs vs XXX% with metformin (AHR XXXX XX% CI 0.700.81). #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:00:03 UTC 5021 followers, XXX engagements
"Evaluating GLP-1 receptor agonists versus metformin as first-line therapy for reducing dementia risk in type X diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:23:18 UTC 5029 followers, XXX engagements
"🦉 Lixisenatide reduced fusiform gyrus activation in obese diabetics (n=29). Lower caloric intake correlated with reduced brain response to food. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:23:20 UTC 5018 followers, XXX engagements
"🦉 All-cause mortality: XXX% with GLP-1 RAs vs XXX% with metformin (AHR XXXX XX% CI 0.810.95). #GLP1 #stroke $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:01:31 UTC 5021 followers, XXX engagements
"🦉 Neuroprotection mechanisms: GLP-1 RAs cross BBB reduce tau amyloid oxidative stress; metformin works via insulin sensitivity. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:03:49 UTC 5021 followers, XXX engagements
"🦉 Recent findings confirm GLP-1 RAs not only reduce atherosclerosis but also restore mitochondrial dynamics by inhibiting Drp-1-driven fission and activating AMPK2. These changes reshape energy metabolism in diabetic hearts. #GLP1 #cardiovascular" @AponiaAnalytics on X 2025-07-18 19:51:08 UTC 5024 followers, XX engagements
"🦉2.5x greater GLP-1 response to intraduodenal glucose in premenopausal women vs men; luteal-phase women also show stronger post-glucose GLP-1 rise. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:02:38 UTC 5019 followers, XXX engagements
"Novel Therapeutic Targets in the Management of Psoriatic Disease $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:32:22 UTC 5028 followers, XXX engagements
"$PRAX $NBIX $BHVN $XENE $AQST $BIIB $DNLI $JAZZ $UCBJF 🌐" @AponiaAnalytics on X 2025-07-10 23:54:55 UTC 5021 followers, XXX engagements
"🦉 GLP-1 receptor agonists extend activity far beyond the natural hormones few-minute lifespan. Engineered to resist DPP-4 they remain active from several hours to X daysamplifying satiety and reducing caloric intake. #GLP1 #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 15:24:50 UTC 5024 followers, XXX engagements
"🦉 Peripheral GLP-1 acts via hepatic portal vein and vagal afferents; knockdown of GLP-1R in vagal neurons increased meal size in rodents. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:18:21 UTC 5018 followers, XXX engagements
"Sanofi to Acquire Vicebio $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:20:23 UTC 5021 followers, XXX engagements
"🦉 Three RCTs now testing GLP-1 or metformin in patients with MCI without diabetes; outcomes will clarify off-label potential. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:26:26 UTC 5021 followers, XXX engagements
"🦉 Weight loss with GLP-1s varied: XXX kg with lixisenatide at XX weeks XXX kg with semaglutide after X years. Weight drop likely drives anti-inflammatory effects. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:59:02 UTC 5024 followers, XXX engagements
"$UNH 🌐 $SOFI $PYPL $BA $SPOT $UPS $MRK $PG $RCL $CVLT $LAD $JBLU $AMT $CARR $AZN $STLA $WGS $PII $DTE $SWK $SYY $PHG $ECL $EXP $CSTM $GLW $JCI $CBRE $ARCC $ABG $ACDVF $NSC" @AponiaAnalytics on X 2025-07-28 17:44:01 UTC 5021 followers, 1130 engagements
"🦉 Liraglutide increased brain glucose transport in AD from XXXX to XXX mol/g/min restoring near-normal BBB glucose uptake. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:40:42 UTC 5030 followers, XXX engagements
"🦉 Despite high ION odds ratios NAION incidence remains low (210 per 100K/year). No consistent causality established. Need for mechanistic studies persists. #GLP1 #stroke $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:18:36 UTC 5032 followers, XXX engagements
"$OSCR $ABVX $OPEN $RIOT $NIO $JOBY $TXN $RIVN $TSLA #sbhawks $SOFI $HAS $QS #AfRam $INTC $TLRY $PLTR 🌐" @AponiaAnalytics on X 2025-07-25 16:58:04 UTC 5023 followers, XXX engagements
"FDA SIDE EFFECTS UPDATE: Kidney Risks Tied to Dehydration From GLP-1 Drugs $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 20:12:23 UTC 5030 followers, XXX engagements
"🦉 Exendin-4 penetrated the brain in X minutes. XXXX% of dose reached brain tissuehighest uptake among GLP-1 RAs. Strong BBB permeability. #GLP1 #Parkinsons $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:20:12 UTC 5025 followers, XXX engagements
"🦉 GCG RAs promote lipolysis and heat generation. fat use stores. Glucose elevation balanced when combined with GLP-1 RAs. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:05:35 UTC 5030 followers, XXX engagements
"🦉 In Parkinsons exenatide/lixisenatide improved motor symptoms; liraglutide boosted non-motor function & quality of life. #Alzheimers #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:29:01 UTC 5018 followers, XXX engagements
"Novo Nordisk (NVO) Signed a MOU With Fangzhou Inc to Focus on Chronic Diseases $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:38:36 UTC 5028 followers, XXX engagements
"🦉 Tirzepatide induces fewer GI side effects than semaglutide. Likely due to GIPR+ GABAergic neurons inhibiting nausea circuits in AP/NTS. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:19:13 UTC 5030 followers, XXX engagements
"🦉 Up to XX% of total body mass lost from semaglutide may be lean mass; XX% for tirzepatide. Impact on sarcopenia risk still unclear. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:17:17 UTC 5030 followers, XXX engagements
"🦉 Dulaglutide in the REWIND trial cut cognitive decline risk by XX% vs. placebo. Newer data reinforces that GLP-1 receptor agonists may yield CNS protection beyond glycemic control. #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 20:57:31 UTC 5030 followers, XXX engagements
"🦉 Pemvidutides liver fat reduction (up to 68.5%) surpassed typical GLP-1 agonists due to added glucagon receptor action. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:35:46 UTC 5025 followers, XXX engagements
"Lobbying Update: $1050000 of SANOFI US SERVICES INC lobbying was just disclosed $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:18:46 UTC 5028 followers, XXX engagements
"🦉GLP-1R activation suppresses orexins only in females; interleukin response weaker in femalesimplying sex divergence in downstream CNS signaling. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:02:21 UTC 5024 followers, XXX engagements
"Exploring the Efficacy and Safety of Tirzepatide in Obesity Management and Cardiometabolic Risk Factors: A Comprehensive Systematic Review and Meta-Analysis $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:30:40 UTC 5023 followers, XXX engagements
"🦉 EVOKE EVOKE+ and the Metformin Alzheimers Trial are testing GLP-1 and metformin in non-diabetics with mild cognitive impairment. Endpoint: dementia prevention. Data due 2026. #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 20:58:09 UTC 5030 followers, XXX engagements
"🦉Liraglutide increased HR in heart failure patients (mean +7 bpm); serious cardiac events: XX% with liraglutide vs X% placebofemales were just XX% of trial. #GLP1 #cardiovascular $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:05:06 UTC 5019 followers, XXX engagements
"$ATNF 🌐 $MCVT $ATNF $ANGH $LOOP $SMX $LHAI $LIDR $YYAI $VCIG $HCTI" @AponiaAnalytics on X 2025-07-26 15:13:04 UTC 5015 followers, XXX engagements
"🦉 Gallbladder risk with GLP-1 RAs: cholelithiasis RR 1.27; cholecystitis RR 1.36; biliary disease RR XXXX. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:29:54 UTC 5018 followers, XXX engagements
"🦉 Study used 1:1 propensity score matching; 87229 patients per arm; all ASMDs XXX. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:03:08 UTC 5021 followers, XXX engagements
"🦉 Liraglutide preserved GLP-1R expression in osteoarthritic cartilage enhanced PKA/CREB signaling and decreased NF-B translocation. Mechanistic evidence for anti-catabolic cartilage effect. #GLP1 #arthritis $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY" @AponiaAnalytics on X 2025-07-20 20:42:25 UTC 5028 followers, XXX engagements
"$SRPT $RCKT $MBRX $DMAC $MAIA $AGEN $XXII $DNA $SDGR $PRAX $CYBN $NKGN $HROW $ALDX $BMY $RDNT $ACTU $TXG $IMAB $NLSP $KROS $AZN $JNJ $BCAB $SXTP $SXTP $OKYO $STXS $LSTA $CLSD $SRPT 🌐" @AponiaAnalytics on X 2025-07-17 16:42:54 UTC 5023 followers, 1793 engagements
"🦉 3.08-point difference in MDS-UPDRS Part III after XX months of lixisenatide vs placebo in early PD. Effect persisted post-washout. #GLP1 #Parkinsons $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:38:58 UTC 5030 followers, XXX engagements
"🦉 2024 network meta-analysis (n=35458): tirzepatide led BP reductionSBP XXXX mmHg DBP XXXX mmHg. Largest effect among all weight-loss agents. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 19:12:25 UTC 5028 followers, XXX engagements
"🦉 No difference in vascular dementia reduction was noted between GLP-1 and metformin users. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:26:02 UTC 5021 followers, XXX engagements
"Unordinary Partnerships: Novo Nordisk Leads Fight Against Obesity In Pakistan $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:40:14 UTC 5025 followers, XXX engagements
"🦉 Brain glucose metabolism amyloid burden and inflammation are targets potentially influenced by GLP-1 therapies. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:25:25 UTC 5021 followers, XXX engagements
"$ORKA $SQNS $LX $AUTL $CNL $GLUE $FFAI $VZ $CLF $DPZ $DLTR $TSLA $PET $SRPT 🌐" @AponiaAnalytics on X 2025-07-21 15:54:41 UTC 5030 followers, XX engagements
"💼Research identifies genetic predictor of weight loss with GLP-1RAs #GLP1 $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:02:20 UTC 5032 followers, XXX engagements
"🦉 Cost: $800$1300/month without insurance in the US. Limits access raises equity concerns in public systems. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:31:41 UTC 5021 followers, XXX engagements
"$DWTX $TC $JG $TCTM $ONCO $NVNI $ETNB $HOLO $MLGO $HWH 🌐" @AponiaAnalytics on X 2025-07-03 15:18:02 UTC 5028 followers, XXX engagements
"$XBI $SRPT $NWBO $CYDY $TNXP $IBRX $MRK $INCY $AMGN $AZN $REGN $SMMT 🌐" @AponiaAnalytics on X 2025-07-26 16:14:47 UTC 5021 followers, 1407 engagements
"🦉 Tirzepatide led glycaemic control with a XXXX% HbA1c drop and XXXX mmol/L fasting glucose outperforming XX other GLP-1RAs. Its dose-efficacy was linear peaking at XX mg weekly. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #glp1 #diabetes" @AponiaAnalytics on X 2025-07-19 15:25:41 UTC 5027 followers, XXX engagements
"$FI $AMZN $UNH $VICI $CNI $GOOGL $ADBE $ASML $CRM $MRK 🌐" @AponiaAnalytics on X 2025-07-27 15:43:44 UTC 5021 followers, XXX engagements
"🦉 Up to XX% of total weight loss from semaglutide and XX% from tirzepatide derives from lean body mass. Yet extremity muscle % remained stable and handgrip strength unchanged after X months. #GLP1 #Tirzepatide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY" @AponiaAnalytics on X 2025-07-20 20:07:28 UTC 5028 followers, XXX engagements
"🦉 Semaglutide was tied to fewer dementia cases while tirzepatide showed stronger results in stroke prevention and survival. Neither drug affected Parkinsons or brain bleeds pointing to a more targeted brain and vessel benefit. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #GLP1" @AponiaAnalytics on X 2025-07-18 22:12:09 UTC 5018 followers, XXX engagements
"$SRDX $MBX $BELFB $SXT $RNA $NEGG $DYN $GCL $EVTL $BRCC $ORN $CTKB $NNE $SCHL $ASPI 🌐" @AponiaAnalytics on X 2025-07-26 15:56:38 UTC 5023 followers, XXX engagements
"French pharma giant Sanofi to acquire British vaccine biotech Vicebio for 1.36B $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:21:50 UTC 5029 followers, XXX engagements
"🦉 GLP-1 drugs remain largely under patentimpacting affordability and accessibility in public healthcare. Bias: GLP-1 users may also benefit from healthier lifestyles or better care. #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 20:58:28 UTC 5023 followers, XXX engagements
"🦉 STEP-4: Discontinued semaglutide = XXX% weight regain. Continued treatment = XXX% further loss. Obesity = chronic condition. #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:30:54 UTC 5018 followers, XXX engagements
"🦉 Patients with initial BMI XX had more significant weight regain post-AOM (+1.66 kg P 0.001) vs those with BMI XX (P=0.33). #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:05:21 UTC 5021 followers, XXX engagements
"🦉Hazard ratio for depression after GLP-1 analog use: XXXX in women vs XXXX in men; for suicidal ideation: XXXX vs XXXX. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:04:00 UTC 5028 followers, XXX engagements
"🦉 X drugs approved for chronic weight loss: liraglutide (Saxenda 2014) semaglutide (Wegovy 2021) tirzepatide (Zepbound 2023). #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:03:38 UTC 5021 followers, XXX engagements
"🦉 Semaglutide caused 2545% lean mass loss during weight reduction. Raises concern in sarcopenic older populations. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:31:12 UTC 5018 followers, XXX engagements
"🦉 GATEWAY Trial: Roux-en-Y bypass + meds cut RHTN prevalence from XX% to X% in X years. Only XXX% in meds-alone arm stopped antihypertensives vs XXXX% post-surgery. #obesity #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 19:14:13 UTC 5018 followers, XXX engagements
"$ORKA $SPX $GOOGL $NVDA $XIAOMI $XK $MSFT $AAPL $TSLA $VWAGY $CAR $HTZ $AMZN $ABNB $DJT $DAL $MP $REMX $THC $INTC $AMD $CRWD $IONQ $BA $CAVA $AMRK $DLTR $EQIX $SHOP $NSC $TD $TSM $TROW $HUM $GL $SQNS $LX $AUTL $CNL $GLUE $FFAI $PET $SRPT $GLD $CL $ZC $ZN $ZT $DX 🌐" @AponiaAnalytics on X 2025-07-21 15:55:26 UTC 5019 followers, XXX engagements
"🦉 Liraglutide crossed the BBB in mice within XX min remained detectable up to X h. Increased cAMP and neurogenesis confirmed CNS activation. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:38:31 UTC 5030 followers, XXX engagements
"🦉 Psychiatric safety: large cohort found no suicidality increase vs. DPP-4i or SGLT-2i (HR range: 0.751.03). #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:32:12 UTC 5016 followers, XXX engagements
"🦉 Those with greater weight loss during AOM treatment were more likely to regain weight after stopping: +1.76 kg at XX weeks (P 0.001). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:05:36 UTC 5021 followers, XXX engagements
"🦉 Even without official approval more patients are trying GLP-1s for T1D. The spotlight is finally shifting from insulin alone to newer longer-acting and smarter treatments that could change the game. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #diabetes #GLP1" @AponiaAnalytics on X 2025-07-18 19:03:41 UTC 5028 followers, XXX engagements
"🦉 Triple agonist retatrutide outperformed semaglutide in shrinking pancreatic tumors in mice. Showed higher antigen presentation markers when combined with gemcitabine. #GLP1 #cancer $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:47:11 UTC 5023 followers, XXX engagements
"🦉 GLP-1 agonists showed sustained protective effect on AUD over X years in long-term users. Duration-based data is rare in addiction pharmacotherapy studies highlighting this as a key finding. #GLP1 #Tirzepatide $NVO $LLY $VKTX $AZN $SNY $GSK $PFE" @AponiaAnalytics on X 2025-07-20 21:12:39 UTC 5030 followers, XXX engagements
"🦉 Medication non-adherence in RHTN: 31.2%. GLP-1 trial adherence ratesSTEP-1: XX% SURMOUNT: 84%. Weekly injections may reduce pill burden and improve adherence. #GLP1 #hypertension $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 19:14:43 UTC 5020 followers, 1046 engagements
"🦉 1573 treated vs XXX control participants; GLP-1 GIP orlistat phentermine-topiramate and naltrexone-bupropion analyzed. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:04:57 UTC 5021 followers, XXX engagements
"🦉 Demographics: Mean BMI was XXXX (non-DM) vs XXXX (DM); age XXXX vs XXXX years; XXXX% vs XXXX% female. These differences likely influenced treatment responsiveness. #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 17:19:07 UTC 5028 followers, XXX engagements
"🦉 REWIND showed dulaglutide reduced MACE in lower-risk T2DM patients; benefits driven by nonfatal stroke. But XX% discontinued by study end. Tolerability remains a limiting factor in long-term outcomes. #GLP1 #stroke $NVO $LLY $ZLDPF $VANI $HIMS $AZN" @AponiaAnalytics on X 2025-07-20 21:27:43 UTC 5030 followers, XXX engagements
"🦉 Weekly titration to XXX mg liraglutide: XXXXX% reached target by week 3; XXXX% by week X. Suggests most patients tolerate standard escalation despite known GI side effects. #GLP1 #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 19:55:07 UTC 5023 followers, XXX engagements
"🦉 Pemvidutide (1.8 mg) achieved max weight loss (-4.3%) and greatest ALT reduction (-13.8 IU/L) at week XX (p=0.029 vs placebo). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:32:29 UTC 5025 followers, XXX engagements
"🦉 Tirzepatide showed only one significant ocular AE: diabetic retinopathy in FAERS (ROR = XXXX XX% CI = 2.074.90). No associations appeared in VigiBase. #GLP1 #diabetes $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:15:58 UTC 5031 followers, XXX engagements
"$ZYNE $ENTA $RLYB $KALA $ASMB $CAPR $RPTX $ASMB $XCUR 🌐" @AponiaAnalytics on X 2025-07-25 21:23:54 UTC 5019 followers, XXX engagements
"Viking Therapeutics Reports Second Quarter 2025 Financial Results and Provides Corporate Update VKTX Stock News $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:19:17 UTC 5019 followers, XXX engagements
"🦉 In mice GLP-1 from ileal L-cells activates a spinal circuit via sympathetic neurons nitric oxide gastric distension eating suppression. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:16:48 UTC 5030 followers, XXX engagements
"@FDA FDAs Concerns with Unapproved #GLP1 Drugs Used for Weight Loss As of April XX 2025 the @FDA has received: XXX reports of adverse events associated with compounded semaglutide. XXX reports of adverse events associated with compounded tirzepatide" @AponiaAnalytics on X 2025-07-29 20:14:49 UTC 5021 followers, X engagements
"🦉 XXXX% vs 11.57%: Weight loss difference between diabetic and non-diabetic groups receiving semaglutide XXX mg. A clinically and statistically significant gap (p 0.001). #weightloss #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI" @AponiaAnalytics on X 2025-07-20 17:17:25 UTC 5028 followers, XXX engagements
"🦉 In vitro GLP-1R loss-of-function mutations impair insulin response; associated with increased adiposity in 200K UK Biobank participants. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:18:46 UTC 5030 followers, XXX engagements
"🦉 Oral GLP-1RA semaglutide: X week half-life via albumin binding; now available daily with an absorption enhancer. Approved 2017. $21.1B in 2023 global sales. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:47:47 UTC 5024 followers, XXX engagements
"🦉 In SELECT semaglutide cut MACE risk by XX% (HR: 0.80; XXX% vs. 8.0%) in patients with obesity and CVD but no diabetes. #stroke #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:27:34 UTC 5018 followers, XXX engagements
"🦉Semaglutide was found in the nucleus accumbens of both sexes but most brain penetration studies used only male animalssex-based brain entry data lacking. #GLP1 #stroke $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:04:39 UTC 5024 followers, XXX engagements
"🦉 Weight regain began at X weeks post-AOM discontinuation and peaked by week 20: +1.50 kg at X weeks +2.50 kg at XX weeks (P XXXXXX for both). #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:03:37 UTC 5023 followers, XXX engagements
"$cycc $BLNE $CTOR $PCSA $Btog $onmd $cyn $pew $sbet $ndra $wff $XXII $gctk $bglc $atnf $ptnm $VLCN 🌐" @AponiaAnalytics on X 2025-07-17 20:34:01 UTC 5023 followers, XXX engagements
"Hims & Hers (HIMS) Faces Legal Storm Post Novo Nordisk Breakup $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-17 16:56:07 UTC 5024 followers, XXX engagements
"🦉 A four-year follow-up is insufficient to fully assess dementia onset. Longitudinal trials needed for causality confirmation. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:25:13 UTC 5021 followers, XXX engagements
"Lilly confirms date and conference call for second-quarter 2025 financial results announcement $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 20:09:33 UTC 5030 followers, XXX engagements
"🦉 Elecsys pTau181 becomes the first IVDR-approved blood test in the EU to exclude Alzheimers. It showed XXXX% NPV and XXXX% false negatives in XXX patients aged 5580 benchmarked against PET amyloid scans. $ROG #Roche #Alzheimers" @AponiaAnalytics on X 2025-07-25 18:35:34 UTC 5030 followers, XXX engagements
"Ozempic & Wegovy Users Report Vision Loss: Could Semaglutide Be Linked to NAION $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:37:02 UTC 5028 followers, XXX engagements
"$UNH 🌐 $SPY $CI $HUM $CVS $OSCR $MOH $CNC $ELV $QQQ" @AponiaAnalytics on X 2025-07-24 18:30:59 UTC 5031 followers, 1064 engagements
"🦉 GLP-1 receptor antagonist exendin-(939) reduced brain uptake of labeled GLP-1 and exendin-4 by 50%. Confirms receptor-mediated BBB transport. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:23:38 UTC 5025 followers, XXX engagements
"Regeneron and Sanofis Dupixent Study: Real-World Insights for Investors $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-12 22:58:59 UTC 5032 followers, XXX engagements
"🦉 Diagnoses in the study relied on routine clinical codingnot confirmed by neuroimaging or biomarkers. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:25:51 UTC 5021 followers, XXX engagements
"Cheaper Wegovy alternative set to launch in Canada as generics enter global markets $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:43:11 UTC 5028 followers, XXX engagements
"🦉 Earlier trials in systolic heart failure didnt show big gains but GLP-1s helped in HFpEF by easing pressure in the heart and reducing inflammation. #GLP1 #heartfailure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:59:13 UTC 5024 followers, XXX engagements
"🦉 No follow-up data linked post-discontinuation regain to progression of metabolic disease but blood pressure increases were noted. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:10:33 UTC 5019 followers, XXX engagements
"🦉 Socioeconomic variablesdiet education healthcare accesslikely influenced results in favor of GLP-1 group. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:27:03 UTC 5021 followers, XXX engagements
"🦉 Most frequent side effects: nausea vomiting diarrhea constipation abdominal pain. Rare risks: pancreatitis and gallstones. Contraindicated in MEN X and medullary thyroid carcinoma. #GLP1 #Tirzepatide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 15:33:42 UTC 5030 followers, XXX engagements
"🦉 In meta-regression variablessex age indication BMI control groupwere not significantly associated with weight regain risk. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:07:54 UTC 5021 followers, XXX engagements
"🦉 Dementia risk in patients aged 80: AHR XXXX (95% CI 0.740.88) with GLP-1 RAs vs metformin. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:02:12 UTC 5021 followers, XXX engagements
"🦉 SUSTAIN-6: semaglutide led to higher DR complications (HR = XXXX XX% CI = 1.112.78) XXX% vs XXX% (P = .02); increased vitreous hemorrhage and photocoagulation need. #GLP1 #diabetes $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:17:44 UTC 5031 followers, XXX engagements
"Hengrui Pharmas Potential Rival to El Lillys Zepbound Leads to XX% Weight Loss in Key Study #glp-1marketing #feedly $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-15 19:31:28 UTC 5021 followers, XXX engagements
"🦉 Tirzepatide example: XX% of lost weight was regained within XX months after switching to placebo post-treatment. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:09:22 UTC 5021 followers, XXX engagements
"$ABVX $PAPL $WLGS $ANEB $AMOD $GPRO $KOSS $DNUT $TMO $GEV $BSX 🌐" @AponiaAnalytics on X 2025-07-23 18:26:28 UTC 5032 followers, XXX engagements
"🦉 GLP-1 RAs suppress appetite via the hypothalamic arcuate nucleus: POMC NPY & AgRP. Resultless intake more energy expenditure. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:03:23 UTC 5030 followers, XXX engagements
"🦉 In XXX women with T2D oral semaglutide reduced HbA1c by XXX% at X months and XXX% at XX months. Median weight loss reached XXX% at XX months; XXXX% achieved XX% weight reduction. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 18:00:58 UTC 5028 followers, XXX engagements
"🦉Anxiogenic effects of GLP-1 and exendin-4 shown in male rodents; only X study confirmed similar results in femalesdata remain sparse. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:04:24 UTC 5019 followers, XXX engagements
"China GLP-1 drug study suggests pound rebound likely after treatment $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:24:51 UTC 5030 followers, XXX engagements
"💼GIPR-Ab/GLP-1 peptideantibody conjugate requires brain GIPR and GLP-1R for additive weight loss in obese mice $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #obesity #GLP1" @AponiaAnalytics on X 2025-07-19 20:19:48 UTC 5024 followers, XXX engagements
"🦉 Effect sizes (Cohens d): waist circumference 1.01; triglycerides 0.53; HbA1c 0.51; final waist d=0.85; final BMI d=0.35; final HbA1c d=0.43. #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:20:25 UTC 5028 followers, XXX engagements
"🦉 Three retrospective studies support GLP-1 efficacy in reducing: (1) AUD onset (2) AUD recurrence (3) intoxication events (4) hospitalizationsacross US and Nordic cohorts. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI" @AponiaAnalytics on X 2025-07-20 21:11:11 UTC 5024 followers, XXX engagements
"🦉 Female sex high baseline BMI and absence of diabetes are emerging predictors of superior response to semaglutide. Supports patient stratification in obesity care. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 17:21:28 UTC 5028 followers, XXX engagements
"🦉 No data on exact GLP-1 agents used. Outcome may vary between liraglutide semaglutide dulaglutide etc. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:26:51 UTC 5021 followers, XXX engagements
"🦉 XXX X% final HbA1c in DD vs. XXX XXX% in nonDD (p=0.01). Yet HbA1c: XXX XXX% vs. XXX XXX% (p=0.8) baseline difference not treatment attenuation. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:18:22 UTC 5028 followers, XXX engagements
"$COUR $SNV $ETN $RVMD $EWC $GNW $GRND $NNDM $YETI $FHN $CHTR $LYV $IRDM $PARA $FNGR $UUP $OPAD $FND $LKQ $EIX $BBWI $OKTA $RNA $SVXY $CMCSA $GEO $JCI $LBRT $PEW $FE" @AponiaAnalytics on X 2025-07-26 15:58:14 UTC 5021 followers, XXX engagements
"#FDAs Concerns with Unapproved #GLP1 Drugs Used for Weight Loss As of April XX 2025 the FDA has received: XXX reports of adverse events associated with compounded semaglutide. XXX reports of adverse events associated with compounded tirzepatide" @AponiaAnalytics on X 2025-07-29 20:16:42 UTC 5021 followers, XX engagements
"🦉 GLP-1 discontinuation may trigger hunger via hormonal changes: reduced satiety delayed gastric emptying lower energy expenditure. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:09:37 UTC 5021 followers, XXX engagements
"$NVCR $SNDX $DCTH $AUTL $GERN $DAWN $IMCR $XBI 🌐" @AponiaAnalytics on X 2025-07-19 19:04:22 UTC 5031 followers, XXX engagements
"🦉 Energy metabolism shift: GLP-1 agonists promote lipid over carb utilization. Preserves muscle glycogen. Exendin-4 induces mitochondrial biogenesis in muscle. AMPK stability vital. #GLP1 #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 19:34:14 UTC 5028 followers, XXX engagements
"$UNH $AAPL $META $MSFT $AMZN $SOFI $HOOD $PYPL $MSTR $BA $V $APLD $CLS $UPS $CVNA $SPOT $LRCX $MARA $QCOM $COIN $RDDT $KGC $F $VRT $WM $ARM $CVS $SBUX $BKNG $STX $CDNS $MO $MRK $RIOT $RMBS $NGD $XOM $NUE $TLRY $ALB 🌐" @AponiaAnalytics on X 2025-07-25 14:49:10 UTC 5021 followers, XXX engagements
"🦉 In FAERS semaglutide showed strong associations with diabetic retinopathy (ROR = XXXXX XX% CI = 13.6221.91) and vitreous hemorrhage (ROR = XXXX XX% CI = 3.878.97). #GLP1 #diabetes $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:14:04 UTC 5031 followers, XXX engagements
"🦉 BMI rebound was seen at XX weeks (+0.70 kg/m) and XX weeks (+0.82 kg/m) post-discontinuation (P 0.0001) reversing earlier reductions. #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:04:21 UTC 5023 followers, XXX engagements
"🦉 24-month minimum follow-up with 6-month washout excluded early-onset dementia and pre-existing cases. #diabetes #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:00:35 UTC 5021 followers, XXX engagements
"🦉 GLP-1Rs in synovium and cartilage regulate TNF- IL-6 IL-1. Liraglutide and dulaglutide reduced MMP-3/13 ADAMTS4/5 and ROS. Results: decreased chondrocyte apoptosis and joint degradation. #GLP1 #Semaglutide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY" @AponiaAnalytics on X 2025-07-20 20:39:37 UTC 5028 followers, XXX engagements
"🦉 Weight regain was consistent regardless of baseline weight ( or XXXXX kg): +1.45 kg vs +2.24 kg; no intergroup significance (P=0.73). #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:07:12 UTC 5018 followers, XXX engagements
"🦉 Subgroup with continuous lifestyle intervention had greater weight regain (+1.83 kg) than those without (+1.1 kg P=0.30). #obesity #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:04:37 UTC 5021 followers, XXX engagements
"🦉 Tirzepatide reduced apnea events by 23.8/hour (95% CI XXXX 17.9). Mechanism: airway fat loss + systemic inflammation drop. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:28:31 UTC 5018 followers, XXX engagements
"🦉 UK health leaders emphasize the need for trials that include biomarker confirmation and longer follow-up durations. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:26:39 UTC 5021 followers, XXX engagements
"🦉 GLP-1R neurons in the area postrema (AP) not NTS drive semaglutide-induced nausea. Selective activation matters for side effect profile. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:17:03 UTC 5030 followers, XXX engagements
"🦉 In X RCTs (n=1872) with type X diabetes patients once-weekly semaglutide XXX mg led to a mean weight reduction of XXXX% (95% CI: XXXX to 5.69) vs placebo. No heterogeneity (I = 0%). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 17:16:40 UTC 5028 followers, XXX engagements
"Malnutrition with use of GLP-1 agonists is an underestimated real world harm $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 19:55:39 UTC 5021 followers, XXX engagements
"$KURA $RPTX $TCRX $IOVA $ACRV $NUVB $RCKT $IDYA $DCTH $RYTM $TARS $ARQT $ASND 🌐" @AponiaAnalytics on X 2025-07-03 22:54:05 UTC 5024 followers, XXX engagements
"🦉 No severe adverse events with pemvidutide; mild nausea (35.7%) vomiting (9.5%) diarrhea (13.1%) constipation (10.7%). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:33:34 UTC 5018 followers, XXX engagements
"🦉 Metformins cognitive benefit remains inconsistent across studies. GLP-1 RAs show broader support in real-world datasets. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:25:01 UTC 5021 followers, XXX engagements
"🦉 In T2DM patients exenatide reversed amygdala overactivation caused by dapagliflozin. Indicates direct CNS interaction. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:25:15 UTC 5021 followers, XXX engagements
"$NKTR $CRVS Conjunctivitis has emerged as a persistent adverse effect tied specifically to IL-4/IL-13 pathway inhibition in atopic dermatitis (AtD) biologics like Dupixent and Ebglyss. New evidence links this to IL-4RA expression on conjunctival goblet cellscreating an inherent ocular vulnerability in this mechanism. This opens a differentiated safety windowand possibly a major market advantagefor $NKTR (Rezpeg) and $CRVS (Soquelitinib). Both use novel mechanisms (Treg proliferation and ITK inhibition respectively) and have shown zero conjunctivitis events across XXX patients combined. If" @AponiaAnalytics on X 2025-07-08 13:41:18 UTC 5019 followers, 1833 engagements
"Hims & Hers Brass Face Suit Over 'Knockoff' Wegovy Sales $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-17 16:52:41 UTC 5023 followers, XXX engagements
"🦉 5-day dosing of semaglutide led to CNS access beyond circumventricular organslateral septum arcuate nucleus and hypothalamic regions. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:18:36 UTC 5030 followers, XXX engagements
"🦉 Semaglutide showed the lowest dropout rate due to side effects and fewer severe GI issues than liraglutide despite nausea remaining frequent in early use. Tolerability remains its comparative edge. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #GLP1" @AponiaAnalytics on X 2025-07-19 15:04:41 UTC 5030 followers, XXX engagements
"🦉 More trials are needed to know how well GLP-1s prevent death or hospital visits in heart failure. Early results are promisingespecially for obese inflamed patients. #GLP1 #HFpEF $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:59:33 UTC 5024 followers, XXX engagements
"🦉 Brown adipose tissue (BAT) immune-regulated. Neuronal GLP-1R deletion energy expenditure UCP1. iNKT cells and monocyte IL-6 activation mediate BAT thermogenesis via GLP-1. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 19:32:42 UTC 5028 followers, XXX engagements
"🦉 In mice with endometrial tumors tirzepatide cut tumor weight regardless of diet. GLP-1 receptor expression in tumors was higher in lean mice then dropped with treatment. #GLP1 #cancer $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:43:55 UTC 5024 followers, XXX engagements
"🦉 No link between faster/slower weight reduction rate during treatment and regain magnitude. +1.94 kg vs +2.0 kg P=0.69. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:08:57 UTC 5021 followers, XXX engagements
"🦉 In age 6079 GLP-1 RAs reduced dementia risk (AHR XXXX XX% CI 0.800.90). No benefit shown for younger groups. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:02:24 UTC 5021 followers, XXX engagements
"🦉 Dropout rate in women: 18.2%. Main reasonsGI intolerance (9.8%) and lack of follow-up (4.4%). No severe adverse events reported; discontinuation not linked to any baseline factor. #GLP1 #Semaglutide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 18:04:49 UTC 5019 followers, XXX engagements
"🦉 Semaglutide activates hypothalamic anorexigenic neurons despite poor BBB permeability. Effect likely via circumventricular organs. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:40:29 UTC 5018 followers, XXX engagements
"🦉 GLP-1 RAs vs metformin in T2DM: dementia incidence dropped by half2.4% vs 4.8%. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:03:34 UTC 5020 followers, XXX engagements
"🦉 Of XX semaglutide-related ION reports XXXX% were unrelated to diabetes. XXXX% were linked to weight-related conditions. Only XXXX% had diabetes. #GLP1 #weightloss $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:14:35 UTC 5032 followers, XXX engagements
"🦉 Sipes prescribed Zepbound in Sep 2024 lost 60+ lbs in X months. Symptoms improved: regular periods reduced cysts joint pain cravings. GLP-1s may modify inflammatory and hormonal drivers of PCOS. #Zepbound #PCOS $NVO $LLY $AZN $SNY $GSK $PFE $RHHB" @AponiaAnalytics on X 2025-07-20 16:01:08 UTC 5030 followers, XXX engagements
"🦉 T2D raises GI cancer risk. Chronic hyperglycemia inflammation and insulin promote tumor growth. GLP-1RAs mitigate all three possibly improving prognosis and response. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:47:29 UTC 5024 followers, XXX engagements
"🦉 At week XX XXXX% on pemvidutide XXX mg had XX ms drop in cT1 (inflammation marker); placebo: X% (p=0.0004). #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:32:43 UTC 5025 followers, XXX engagements
"🦉 At week XX post-AOM GLP-1 users had significant regain: +1.78 kg vs control (95% CI 0.762.80 P=0.006). Non-GLP-1 treatments showed no significant gain. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:03:52 UTC 5018 followers, XXX engagements
"🦉 Tirzepatide (Mounjaro 2022) and Zepbound (2023) are dual GLP-1/GIP receptor agonists. Both FDA-approved for obesity or type X diabetes. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:03:07 UTC 5021 followers, XXX engagements
"$JUSHF $MSOS $YOLO $PSIL $CXXIF $GLASF 🌐" @AponiaAnalytics on X 2025-07-11 13:20:40 UTC 5028 followers, XXX engagements
"🦉 This observational study can't prove causality but it strengthens a recurring pattern: GLP-1 receptor agonists are linked with reduced risk of Alzheimers and all-cause dementia in T2D. #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI" @AponiaAnalytics on X 2025-07-23 20:59:19 UTC 5028 followers, XXX engagements
"$UNH $MOH $CNC $SPY $QQQ $OSCR $HUM $ELV $CI $CVS 🌐" @AponiaAnalytics on X 2025-07-24 18:45:27 UTC 5027 followers, XXX engagements
"Novo Nordisk gets EU backing to update Alhemo label (NVO:NYSE) $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:37:20 UTC 5025 followers, XXX engagements
"A decade of progress in type X diabetes and cardiovascular disease: advances in SGLT2 inhibitors and GLP-1 receptor agonists - a comprehensive review $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:22:21 UTC 5023 followers, XXX engagements
"🦉 At XX weeks pemvidutide (1.8 mg) cut liver fat by XXXX% vs. XXX% placebo; XXXX% achieved XX% LFC drop XXXX% normalized (5% fat). #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:32:09 UTC 5025 followers, XXX engagements
""Disruptions in Aesthetic Medicine: A Global Analysis of GLP-1 Agonists Using Punctuated Equilibrium Framework" $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:25:40 UTC 5033 followers, XXX engagements
"Hims & Hers plans Canada expansion to time patent cliff for Novos Weogvy $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-12 23:02:48 UTC 5021 followers, XXX engagements
"$BYND $PMN $AIRE $DEVS $PET $BENF $DYNX $HSDT $SABS $AMIX $OPAD $SPY 🌐" @AponiaAnalytics on X 2025-07-21 19:14:22 UTC 5030 followers, XXX engagements
"🦉 Among XX cases with age data XX were children. Infection sources remain unclear but poultry exposure remains the likely vector. The outbreak remains confined to mainland China. #H9N2 #China @CIDRAP" @AponiaAnalytics on X 2025-07-23 20:03:16 UTC 5025 followers, XX engagements
"🦉 Despite continuous intervention patients still regained weighthighlighting possible biological dominance over behavioral control. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:10:16 UTC 5021 followers, XXX engagements
"$BIIB $ACAD $BMY $OTSKY $HLBBF $EIASY $PFE $NVS $JNJ $LLY $ABBV $NMRA 🌐" @AponiaAnalytics on X 2025-07-28 16:17:46 UTC 5019 followers, XXX engagements
"B.C. limits sale of X more diabetes drugs used for weight loss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-18 16:06:51 UTC 5029 followers, XXX engagements
"🦉 Retinopathy risk may relate to rapid glucose shifts: early worsening then improvementconsistent with DCCT/UKPDS trials. Not specific to semaglutide alone. #GLP1 #diabetes $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:17:00 UTC 5032 followers, XXX engagements
"🦉 87229 matched patients per group: GLP-1 RAs reduced dementia incidence to XXX% vs XXX% with metformin (AHR XXXX XX% CI 0.850.95). #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:59:25 UTC 5021 followers, XXX engagements
"Kidney Outcomes With Glucagon-Like Peptide-1 Receptor Agonists Versus Other Glucose-Lowering Agents in People With Type X Diabetes: A Systematic Review and Meta-Analysis of Real-World Data $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:22:08 UTC 5030 followers, XXX engagements
"$MRK $MRK $PTGX $BMY $NUVL $BIIB $KRRO $SRPT 🌐" @AponiaAnalytics on X 2025-07-21 18:45:27 UTC 5021 followers, XXX engagements
"💼Shifting obesity treatment paradigms: Trends of glucagon-like peptide-1 receptor agonists and bariatric surgery in the United States $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #obesity #GLP1" @AponiaAnalytics on X 2025-07-18 14:54:10 UTC 5019 followers, XXX engagements
"🦉 5%8% of U.S. adults use GLP-1RAs. With cancer and diabetes both rising with age overlap of GLP-1RA use in cancer patients is growing fast. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:45:06 UTC 5024 followers, XXX engagements
"Novo Nordisk (NVO) Gains Positive CHMP Nod for Alhemo Label Expa $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:39:28 UTC 5025 followers, XXX engagements
"💼Advances in GLP-1 receptor agonists for pain treatment and their future potential $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #GLP1" @AponiaAnalytics on X 2025-07-19 21:47:16 UTC 5030 followers, XXX engagements
"$ATYR $PRAX $ANAB $ARCT $BNTC $DRUG $EWTX $GPCR $KRRO $NAMS $NKTR $PRAX $TVRD $UPB $VTYX $PRTA $TECX 🌐" @AponiaAnalytics on X 2025-07-07 13:26:43 UTC 5024 followers, XXX engagements
"🟠 #IntelliaTherapeutics has dosed the first participant in a global Phase III trial for #NTLA-2002 targeting hereditary angioedema (#HAE). #Intellia @intelliatx $NTLA #CRISPR #biotech" @AponiaAnalytics on X 2025-01-24 18:17:54 UTC 5027 followers, XX engagements
"$ITOS 🌐 $PMN $HSDT $ZIMV $SABS $NCNA $AUTL $EVO" @AponiaAnalytics on X 2025-07-21 15:11:49 UTC 5031 followers, XXX engagements
"🦉 In a 174000-person retrospective cohort GLP-1 receptor agonists were linked to a XX% lower risk of all-cause dementia vs. metformin over X years. Source: Mingyang Sun et al. BMJ Open Diabetes Res & Care. #GLP1 $NVO $AZN $SNY $GSK $PFE $RHHBY $VKTX" @AponiaAnalytics on X 2025-07-23 20:51:15 UTC 5031 followers, XXX engagements
"Roche joins Pfizer Amgen in abandoning obesity drug development - CHOSUNBIZ $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:34:36 UTC 5030 followers, XXX engagements
"🦉 Liraglutide increased intrinsic connectivity in the DMN of AD-risk individuals. Suggests central neural activity beyond glycemic effect. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:24:59 UTC 5025 followers, XXX engagements
"🦉 VaD risk remained unchanged between groups: XXX% vs 1.3%; AHR XXXX (95% CI 0.911.14). #dementia #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:00:18 UTC 5021 followers, XXX engagements
"🦉 Roche's pTau-217 test outperformed ratio-based assays in temperature stability. This simplifies logistics and supports broader use. Both Elecsys tests target earlier less invasive Alzheimers exclusion. $ROG #Roche #Alzheimers" @AponiaAnalytics on X 2025-07-25 18:35:34 UTC 5023 followers, XXX engagements
"🦉 12-month lixisenatide trial in early PD: motor decline slowed by XXXX points vs placebo. Benefit persisted post-washout. #GLP1 #Parkinsons $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:20:44 UTC 5025 followers, XXX engagements
"🦉 XXX mg pemvidutide lowered liver fat XXXX% placebo just 4.4%; ALT dropped XX IU/L in patients starting XX IU/L (p=0.006). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:35:59 UTC 5025 followers, XXX engagements
"$CLSD $ABVX $ANEB $CLSD $IMNN $GHRS $PHVS $IOVA $LTRN 🌐" @AponiaAnalytics on X 2025-07-23 20:46:05 UTC 5021 followers, XXX engagements
"🦉 Semaglutide was significantly associated with ischemic optic neuropathy: FAERS ROR = XXXXX (95% CI = 8.1515.16) VigiBase ROR = XXXXX (95% CI = 16.75280.67) both P .0001. #GLP1 #diabetes $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:13:46 UTC 5031 followers, XXX engagements
"🦉 Retatrutide: a triple GLP-1/GIP/GCG agonistSBP fell XXXX mmHg DBP XXX mmHg in 48-week phase II trial. Up to XX% stopped 1+ antihypertensive drug. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 19:13:17 UTC 5023 followers, XXX engagements
"🦉 Liraglutide increased BBB glucose transport from XXXX to XXX mol/g/min in AD patientsmatching healthy levels. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:21:45 UTC 5025 followers, XXX engagements
"🦉 Prior liraglutide RCTs showed cognitive improvement and less cerebral amyloid; aligns with this cohort study. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:04:17 UTC 5021 followers, XXX engagements
"🦉 Semaglutide vs dulaglutide: higher reporting odds in VigiBase for ION (ROR = 75.01) DR (ROR = 1.96) vitreous hemorrhage (ROR = 7.88). #GLP1 #diabetes $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:17:28 UTC 5032 followers, XXX engagements
"🦉 With FDA removing semaglutide and tirzepatide from its shortage list 503A pharmacies now face stricter compounding rules tied to essentially a copy standards and specific clinical difference justifications. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #GLP1" @AponiaAnalytics on X 2025-07-19 14:45:54 UTC 5030 followers, XXX engagements
"🦉 With diabetes: regain +2.24 kg. Obesity alone: +1.31 kg. Difference between subgroups not significant (P=0.06). #diabetes #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:07:26 UTC 5018 followers, XXX engagements
"🦉 XXXX% of Instagram before/after posts were likely AI-generated (DeepFake-o-meter). TikToks average was 51.6%. High AI use may distort expectations and fuel unregulated semaglutide use. #GLP1 #Semaglutide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 16:23:09 UTC 5027 followers, XXX engagements
"🦉 Dopaminergic modulation. GLP-1 agonists suppress mesolimbic dopamine. May reduce reward-seeking behavior but raise risk of depression in DRD2 Taq1A polymorphism carriers. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:34:55 UTC 5028 followers, XXX engagements
"🦉 In just six weeks tirzepatide slashed calorie intake by 72%without participants trying to restrict food. Unlike semaglutide or liraglutide it blunted hunger by rewiring activity in key brain regions tied to cravings. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #tirzepatide" @AponiaAnalytics on X 2025-07-18 22:17:52 UTC 5021 followers, XXX engagements
"🦉 GLP-1 users had a XX% lower dementia risk than metformin users over X years in a 174000-person observational study. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:23:11 UTC 5021 followers, XXX engagements
"🦉 Four design gaps: no data on treatment duration unmatched group characteristics dementia diagnoses not biomarker-confirmed and a short 4-year observation window. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 20:56:56 UTC 5032 followers, XXX engagements
"🦉 Exclusion: prior dementia ESRD dialysis psychiatric/neurodegenerative disorders or crossover drug use. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:03:22 UTC 5021 followers, XXX engagements
"🦉 XXXX% of injected exendin-4 reached brain tissue. Liraglutide and semaglutide showed no significant brain uptake in the same study. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:38:45 UTC 5030 followers, XXX engagements
"🦉GLP-1 plus estrogen in female rats: enhanced brain activation synergistic food reward suppression greater weight loss restored post-ovariectomy satiety response. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:00:34 UTC 5021 followers, XXX engagements
"Semaglutide-Induced Small Bowel Pseudo-Obstruction and Ileitis in a Patient With Type X Diabetes: A Case Report $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:26:52 UTC 5028 followers, XXX engagements
"MaineGeneral files lawsuit against insulin makers and pharmacy benefit managers for inflating prices $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:20:13 UTC 5032 followers, XXX engagements
"🦉 Cocaine-seeking behavior after EX-4 injections into VTA NAc and LDT. Dosages: 0.0050.05 g. Result: blocked cue/drug-induced reinstatement in male rats. #GLP1 #cocaine $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 18:14:11 UTC 5031 followers, XXX engagements
"🦉 Blood pressure lowered within X weeks of liraglutide therapy suggesting vascular effects beyond weight loss. DURATION-1 showed XXX mmHg SBP drop with exenatide X mg/week; other trials reported less. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $VKTX" @AponiaAnalytics on X 2025-07-20 21:29:59 UTC 5030 followers, XXX engagements
"Obesity and the Gut-Brain Axis in Type X Diabetes Mellitus: Terra Incognita $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:44:20 UTC 5029 followers, XXX engagements
"🦉 In STEP-HFpEF weekly semaglutide (2.4 mg) cut CRP levels by XXXX% vs just XXX% on placebo. Patients lost XXXX% body weight and felt significantly better physically. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:53:59 UTC 5024 followers, XXX engagements
"🦉 STEP-HFpEF trials: semaglutide improved heart failure symptoms exercise toleranceregardless of diabetes status. #bloodpressure #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:28:02 UTC 5018 followers, XXX engagements
"🦉 GLP-1 RAs cut LDL triglycerides and hepatic glucose production. thermogenesis. Net result: improved fat mobilization higher energy use. #GLP1 #diabetes $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:04:56 UTC 5030 followers, XXX engagements
"🦉 5065% of lost weight is typically regained within XX months after GLP-1RA cessation. SELECT trial showed XXX% placebo-subtracted loss at XXX weeks. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:18:06 UTC 5021 followers, XXX engagements
"Novel glucose-lowering agents that benefit diabetic foot: icing on the cake $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-17 16:47:55 UTC 5024 followers, XXX engagements
"💼Pfizer Invites Public to View and Listen to Webcast of August X Conference Call with Analysts $PFE NEW YORK June 25Pfizer Inc. (NYSE: PFE) invites investors and the general public to view and listen to a webcast of a conference call with investment analysts at 10:00 a.m. EDT on Tuesday August X 2025. The purpose of the call is to provide an update on Pfizers results as reflected in the companys Second Quarter 2025 Performance Report to be issued that morning" @AponiaAnalytics on X 2025-07-09 12:13:46 UTC 5021 followers, 1992 engagements
"🦉 Sulfonylurea and insulin use in DM may blunt weight reduction from GLP-1 agonists. Insulin promotes fat storage opposing the catabolic effects of semaglutide. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 17:20:58 UTC 5019 followers, XXX engagements
"🦉Roche axes Carmot obesity asset X cancer drugs in R&D clear-out $ROG #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 13:32:48 UTC 5026 followers, XXX engagements
"🦉 One hormone three effectsstimulates insulin (when glucose is high) suppresses glucagon and delays gastric emptying. Together these regulate post-meal glucose and appetite with high precision. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 15:29:23 UTC 5028 followers, XX engagements
"🦉 Among 12.9M FAERS reports semaglutide was involved in 29934 AE cases. XXXX% were female mean age XXXX years. Most ocular AEs affected women. #GLP1 #stroke $NVO $LLY $AZN $SNY $VKTX $GSK $PFE $ZLDPF $VANI $MRK $BIIB" @AponiaAnalytics on X 2025-07-21 20:18:02 UTC 5033 followers, XXX engagements
"🦉 Patients on GLP-1 RAs may also benefit from healthier lifestylesconfounding the dementia outcomes. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:26:14 UTC 5021 followers, XXX engagements
"🦉 Peripheral effect: ghrelin peptide YY & cholecystokinin slower gastric emptying stronger satiety signals. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:04:07 UTC 5030 followers, XXX engagements
"🦉 GLP-1 RAs lowered Alzheimers risk to XXX% vs XXX% with metformin (AHR XXXX XX% CI 0.830.94). #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:59:45 UTC 5021 followers, XXX engagements
"🦉 Oral semaglutide reduced MACE in SOUL trial; orforglipron (non-peptide oral) shows promise in phase X for weight and glucose control. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:31:26 UTC 5015 followers, XXX engagements
"🦉 GLP-1 RAsliraglutide semaglutide exenatide beinaglutide AMG133were the only group consistently linked to significant post-treatment weight regain. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:04:06 UTC 5018 followers, XXX engagements
"🦉 VaD reduction was observed only in females (AHR XXXX XX% CI 0.790.99) not in males or overall. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:01:59 UTC 5021 followers, XXX engagements
"Dulaglutide markedly prevents peritoneal fibrosis in a rodent model of chronic kidney disease: Insights into the pathogenesis $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:44:08 UTC 5029 followers, XXX engagements
"Viking Therapeutics Inc. (NASDAQ:VKTX) Q2 2025 Earnings Call Transcript $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:43:30 UTC 5029 followers, XXX engagements
"🦉 Correlations: female sex + weight loss (r=0.2 p=0.02); insulin use weight loss (r=0.347 p0.001); alcohol XX g/day weight loss (r=0.229 p=0.01). #GLP1 #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:18:51 UTC 5029 followers, XXX engagements
"Sanofis Phase X Study on Frexalimab: A Potential Game-Changer for Multiple Sclerosis Treatment $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:21:32 UTC 5030 followers, XXX engagements
"$PMN $DYNX $HSDT $WLGS $IXHL $TNFA $SQNS $LMFA $AIRE $GCTK $BNAI $SPY 🌐" @AponiaAnalytics on X 2025-07-21 19:27:02 UTC 5019 followers, XXX engagements
"💼Roche nets European approval for blood test to rule out Alzheimers disease $ROG #Roche #Alzheimers" @AponiaAnalytics on X 2025-07-25 18:35:33 UTC 5030 followers, XXX engagements
"$NCNA $HCTI $SPZI $PNPN $CNRC $SAGMF $CFTN $ADHC $TWOH $CBRA $EHVVF ✍" @AponiaAnalytics on X 2025-07-16 19:25:36 UTC 5024 followers, XXX engagements
"🦉 Real-world semaglutide use dropped TUD-related diagnosis (HR: 0.68) cessation meds (HR: 0.32) and counseling (HR: 0.72). #GLP1 #stroke $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:29:27 UTC 5018 followers, XXX engagements
"🦉 GLP-1 RAs remain under patent protection. Could skew outcomes by selecting for patients with higher socioeconomic status. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:24:49 UTC 5018 followers, XXX engagements
"🦉 XX% and XX% lower risk of AUD-related hospitalization with semaglutide and liraglutide respectively per Swedish population-wide analysis. Approved AUD meds reduced this risk by only 2%. #GLP1 #Semaglutide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY" @AponiaAnalytics on X 2025-07-20 21:09:25 UTC 5019 followers, XXX engagements
"$ZYNE $ENTA $RLYB $KALA $ASMB $CAPR $RPTX $ASMB $XCUR 🌐" @AponiaAnalytics on X 2025-07-28 16:46:19 UTC 5031 followers, XX engagements
"Swedish biotech backed by former Novo Nordisk researcher completes share issue above expectations $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-23 21:25:18 UTC 5033 followers, XXX engagements
"🦉 Pemvidutide XXX mg significantly reduced triglycerides (-130.4 mg/dl p=0.032) and systolic BP (-10.4 mmHg p0.001) vs placebo. #bloodpressure #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:34:57 UTC 5030 followers, XXX engagements
"🦉 X XXX% weight loss in DD vs. XXX XXX% in nonDD (p=0.4). BMI weight waist reduction showed no significant group difference. #GLP1 #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:17:37 UTC 5028 followers, XXX engagements
"🦉 GIP RAs: insulin glucagon regulate lipid storage. When combined with GLP-1 RAs metabolic flexibility increases. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:05:11 UTC 5021 followers, XXX engagements
"🦉 Weight Loss That Lasts: Reviewing the Long-Term Impact of GLP-1 Receptor Agonists In SELECT (Kushner 2025) semaglutide XXX mg reduced serious adverse events in obese CVD patients. GI side effects caused higher discontinuation. #SELECT #safety $NVO $SNY" @AponiaAnalytics on X 2025-07-20 14:20:56 UTC 5031 followers, XX engagements
"🦉 In STEP-1 semaglutide XXX mg weekly cut SBP by XXX mmHg DBP by XXX mmHg and XX% of patients stopped antihypertensives. Duration: XX weeks. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-24 19:11:29 UTC 5030 followers, XXX engagements
"🦉 Despite lack of VAT difference liraglutide reactivated GLUT4 MAPK PPAR- reduced TGF- and lowered TNF- IL-6 IL-1. Mechanisms may explain stronger metabolic benefit in T2D. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 19:56:22 UTC 5028 followers, XXX engagements
"$capc $hmbl $gtch $atvk $qind $ipsi $rdar $psww $psru $rkar $hysr $shmp $nwbo $smce $hcti 🌐" @AponiaAnalytics on X 2025-07-18 17:28:44 UTC 5030 followers, 2514 engagements
"🦉 Semaglutide indirectly activated arcuate POMC neurons despite low BBB permeabilityvia CVO engagement. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:22:03 UTC 5025 followers, XXX engagements
"🦉 Liraglutide didnt boost ejection fraction in older trials but did reduce left atrial size and pressurekey signs of HFpEF improvement. #GLP1 #heartfailure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:55:53 UTC 5024 followers, XXX engagements
"🦉 Dulaglutide failed to improve smoking cessation in RCT; semaglutide lowered real-world smoking-related healthcare use. #GLP1 #stroke $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:31:59 UTC 5021 followers, XXX engagements
"🦉 Weekly semaglutide or dulaglutide shrank epicardial fat around the heartfat that fuels inflammation and worsens heart failure in obesity. #GLP1 #heartfailure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:54:53 UTC 5024 followers, XXX engagements
"🦉 GLP-1 RAs produce 1520% weight losshigher than other anti-obesity drugs (39%) and less than bariatric surgery (22.7 kg). #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:27:15 UTC 5018 followers, XXX engagements
"🦉 Triple agonist retatrutide (GLP-1/GIP/glucagon) shows highest weight loss in early trials; potential next-gen obesity drug. #obesity #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:32:26 UTC 5021 followers, XXX engagements
"🦉 12-week oral semaglutide study: XXXX% energy intake vs placebo stronger satiety appetite control. Effects due to increased PYY decreased postprandial GLP-1 and cravings. #Semaglutide #weightloss $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 19:36:06 UTC 5030 followers, XXX engagements
"🦉 With statins: dementia risk further reduced (AHR XXXX XX% CI 0.740.91). With insulin: AHR XXXX (95% CI 0.700.86). #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:02:40 UTC 5021 followers, XXX engagements
"Fake weight loss drugs spark alarm: Warning sent to FDA FTC over counterfeit GLP-1s $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-18 16:07:42 UTC 5030 followers, XXX engagements
"💼New investigation launched after health experts find potentially fatal side effect of taking weight loss drugs According to UK reports there have been approximately XX deaths linked to this condition thanks to the GLP1 drugs. $NVO $LLY $AZN $SNY $GSK" @AponiaAnalytics on X 2025-07-20 16:32:47 UTC 5030 followers, XXX engagements
"🦉 XXX T2DM patients treated with GLP1 RAs X months: XXXX% (53/115) had documented depressive disorder (DD) via clinical diagnosis chronic antidepressants or BDI XX. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:15:09 UTC 5028 followers, XXX engagements
"🦉 Active control trials showed a regain of +2.37 kg (95% CI 0.304.44 P=0.02) slightly more than placebo control trials (+1.72 kg P0.001). #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:06:55 UTC 5020 followers, XXX engagements
"🦉 XXX mg/day liraglutide over X months: G2 (obesity + T2D) had greater A1c% reduction (1.15%; p = 0.001) vs. G1 (obesity + prediabetes) (0.5%; p = 0.000). Indicates enhanced glycemic response in T2D. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE" @AponiaAnalytics on X 2025-07-20 19:50:20 UTC 5029 followers, XXX engagements
"🦉 GLP-1 activation in the brainstem (NTS) boosts serotonin and glutamate triggering fullness and limiting food reward signaling. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:03:50 UTC 5030 followers, XXX engagements
"🦉 In obese mice: GLP-1RA upregulated muscle oxidative fibers glycogen stores and mitochondrial activity. In humans muscle fatty infiltration decreased despite modest SMI reduction. #GLP1 #Tirzepatide $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 20:39:05 UTC 5028 followers, XXX engagements
"$MDGL $IVA $AKRO $ALGS $VKTX $ETNB $SGMT $LLY #MASH 🌐" @AponiaAnalytics on X 2025-07-22 22:02:06 UTC 5030 followers, XXX engagements
"🦉 Lean mass loss on GLP-1RAs is less than fat mass loss. In many cases lean mass proportion increases. Exercise preserves muscle and boosts therapy response. #GLP1 #cachexia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:48:03 UTC 5024 followers, XXX engagements
"🦉 LEADER trial: liraglutide reduced major cardiovascular events in type X diabetes patients. Heart protectionnow a confirmed clinical endpoint for several GLP-1 receptor agonists. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF" @AponiaAnalytics on X 2025-07-20 15:31:52 UTC 5028 followers, XXX engagements
"🦉 In AD trials liraglutide increased default mode network connectivitysuggesting neural target engagement beyond metabolic control. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:41:06 UTC 5021 followers, XXX engagements
"💼Beyond Blood Sugar: A Scoping Review of GLP-1Receptor Agonists in Cardiovascular Care $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #GLP1" @AponiaAnalytics on X 2025-07-19 21:48:57 UTC 5028 followers, XXX engagements
"🦉 All patients showed clinical insulin resistance signs. Baseline visceral fat: G1 = XXXX (IQR 830); G2 = XXXX (IQR 920). Liraglutide improved insulin sensitivity in both. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 19:55:59 UTC 5028 followers, XXX engagements
"HIMS Lawsuit Alert Hims & Hers Faces Class Action Lawsuit After Wegovy Scandal $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-22 19:28:14 UTC 5023 followers, XXX engagements
"🦉 XXXX% on pemvidutide XXX mg reached XX% liver fat reduction at week XX compared to XXX% placebo (p0.0001). #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:33:50 UTC 5025 followers, XXX engagements
"🦉 GLP-1 drugs turn down NF-kB a major switch that controls inflammation. In animal studies this helped reduce organ stress and damage. #GLP1 #inflammation $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:55:08 UTC 5024 followers, XXX engagements
"🦉 In PCOS GLP-1 RAs improved menstrual regularity (SMD: 1.72) and pregnancy rates (RR: 1.72) vs. metformin. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:28:44 UTC 5018 followers, XXX engagements
"🦉 Baseline metabolic disparity: DD group had HbA1c XXX X% vs. XXX XXX% (p=0.01); fasting glucose XXXXX XXXX vs. XXXXX XXXX mg/dL (p=0.02); triglycerides XXXXX XXXXX vs. XXXXX XXXX mg/dL (p=0.001). #GLP1 #diabetes $NVO $LLY" @AponiaAnalytics on X 2025-07-20 19:15:50 UTC 5028 followers, XXX engagements
"🦉 Younger people are picking up GLP-1s faster but those under XX still lean more toward surgery. Only a tiny fraction who start GLP-1s end up getting surgery showing most stick to one route. $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #obesity #GLP1" @AponiaAnalytics on X 2025-07-18 14:54:11 UTC 5027 followers, XXX engagements
"🦉 Blunted response in DM group may stem from: 1) insulin resistance 2) chronic hyperinsulinemia 3) glycemic control reducing glycosuriadiminishing net energy loss. #diabetes #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-20 17:18:53 UTC 5020 followers, XXX engagements
"GLP1 weight loss injections may reduce asthma symptoms $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-26 15:36:46 UTC 5030 followers, XXX engagements
"🦉 XXXX% of Ser8GLP-1 entered brain parenchyma in mice. Entry was passive not saturableindependent of lipid solubility. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 17:22:26 UTC 5025 followers, XXX engagements
"💼Comparative effectiveness of GLP-1 receptor agonists on glycaemic control body weight and lipid profile for type X diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #glp1 #diabetes" @AponiaAnalytics on X 2025-07-19 15:25:40 UTC 5024 followers, XXX engagements
"🦉 Dual/triple agonists (GLP-1/GIP/GCG) target multiple receptorssynergistic benefits: appetite suppression thermogenesis glycemic control. #GLP1 #obesity $LLY $NVO $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:05:23 UTC 5021 followers, XXX engagements
"🦉 High CRP = higher heart risk. GLP-1 drugs drop CRP levels substantiallyshowing they ease inflammation even when blood sugar isnt the issue. #GLP1 #bloodpressure $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:58:18 UTC 5024 followers, XXX engagements
"🦉 Alzheimers Research UK emphasized observational studies cant assess GLP-1 RAs' effects on dementia-causing biology. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:25:39 UTC 5021 followers, XXX engagements
"🦉Women in STEP trials showed greater mean weight loss with semaglutide: XXXX% vs XXX% (STEP 1) XXX% vs XXX% (STEP 2) XXXX% vs XXX% (STEP 4). #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 18:00:15 UTC 5029 followers, XXX engagements
"🦉 Semaglutide reached XXXX% total weight loss in STEP-1 at XX weeks but only XXX% in SELECT after XXX weeks. Trial design impacts outcomes. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 16:18:59 UTC 5030 followers, XXX engagements
"🦉 In Alzheimers liraglutide reduced brain atrophy and slowed cognitive decline by XX% over X year vs. placebo. #dementia #GLP1 $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 16:29:14 UTC 5018 followers, XXX engagements
"🦉 Cachexia: XX% of cancer deaths. Risk that GLP-1RAs may worsen it by inducing muscle loss. But semaglutide-treated obese mice showed improved muscle fiber size and density. #GLP1 #cachexia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-25 21:46:06 UTC 5024 followers, XXX engagements
"🦉 Pemvidutide at XXX mg weekly reduced liver volume by XXXX% vs. placebo's +1.4% (p0.001) correlating with liver fat decrease. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-27 15:35:14 UTC 5025 followers, XXX engagements
"🦉 Kaplan-Meier curves confirm lower dementia incidence with GLP-1 RAs throughout follow-up. #GLP1 #Alzheimers $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:04:50 UTC 5021 followers, XXX engagements
"💼Activation of GLP-1 receptors enhances the osteogenic differentiation process of STRO-1-positive BMSCs $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS #GLP1" @AponiaAnalytics on X 2025-07-19 20:50:49 UTC 5028 followers, XXX engagements
"🦉 Weight Loss That Lasts: Reviewing the Long-Term Impact of GLP-1 Receptor Agonists Head-to-head trials directly comparing tirzepatide vs. semaglutide or exenatide remain absent. Agent selection remains data-limited. #GLP1 #trialgap $LLY $VKTX" @AponiaAnalytics on X 2025-07-20 14:25:28 UTC 5030 followers, XXX engagements
"SK bioscience Sanofi receive approval for pneumococcal vaccine trials in China - CHOSUNBIZ $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-18 16:05:40 UTC 5033 followers, XXX engagements
"🦉 GLP-1 RAs modulate BDNF enhance synaptic plasticity and strengthen blood-brain barrier integrity. #GLP1 #dementia $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 17:04:31 UTC 5021 followers, XXX engagements
"🦉 Weight loss persisted through week X post-AOM: WMD XXXX kg (P = 0.85) but regain started by week X and climbed through week XX. #GLP1 #obesity $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX $VANI $HIMS" @AponiaAnalytics on X 2025-07-28 20:07:39 UTC 5018 followers, XXX engagements
"🦉 At XX months XXXX% of women and XXXX% of men on oral semaglutide reached HbA1c 7%. No significant sex difference in glycaemic control dose persistence or side effect profile. #GLP1 #diabetes $NVO $LLY $AZN $SNY $GSK $PFE $RHHBY $ZLDPF $VKTX" @AponiaAnalytics on X 2025-07-20 18:03:54 UTC 5028 followers, XXX engagements