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@lowmegatron "Cocoa supports gut barrier integrity thereby lowering circulating endotoxin. High endotoxin causes: ➥ Diabetes ➥ Insulin resistance ➥ Cardiovascular disease ➥ Dementia ➥ Anhedonia ➥ Lowestosterone ➥ Thyroid issues ➥ Sociopathic tendencies Cocoa treatment ameliorated metabolic endotoxemia (40% reduction in plasma endotoxin) and improved gut barrier function. You need to ensure that you get cocoa/chocolate that is low in heavy metals. PMCID: PMC4034375 🐁"
X Link @lowmegatron 2025-10-06T20:55Z 29.8K followers, 84.3K engagements

""In the 1940s carrageenan a polysaccharide made from a type of seaweed was recognized as a dangerous allergen. Since then it has become a standard laboratory material to use to produce in-flammatory tumors (granulomas) immunodeficiency arthritis and other in-flammations. Years ago I noticed that Oregon was one of the few states that still had real whipping cream and cottage cheese without additives so I have been trustingly using cream in my coffee every day. Last week I noticed that my cream listed carrageenan in its ingredients. Over the years I have avoided carrageenan-containing foods"
X Link @lowmegatron 2025-10-13T15:55Z 29.8K followers, 85.2K engagements

"Its insane that hospitals pump seed oils directly into the veins of sick people. Seed oils were once used in organ transplants to suppress the immune system. Seed oils went from 3-8% of calories in a century with catastrophic results. If you end up in the hospital on TPN (nutrition directly into the veins) this could increase to 20-60% of your total calorie intake. This is mostly linoleic acid the n-6 fatty acid which was used for immune suppression in organ transplants. There is a shift to reducing the amount of seed oils in the mix but it remains at a harmful level. Replacing it with fish"
X Link @lowmegatron 2025-10-15T15:55Z 29.8K followers, 56.7K engagements

"GM ☕ Antidepressant mechanisms of coffee: Boosts dopamine Lowers cortisol Lowers inflammation Increases testosterone Strengthens the gut barrier Lowering endotoxin Reduces prolactin Increases energy"
X Link @lowmegatron 2025-10-11T13:55Z 29.8K followers, 13.4K engagements

"Penetrating red light is possibly the fundamental anti-stress factor for all organisms. The chronic deficiency of such light is I think the best explanation for the deterioration which occurs with aging. Enzyme changes free radical changes structural and respiratory changes are all involved as consequences of darkness stress. Ray Peat"
X Link @lowmegatron 2025-10-09T15:26Z 29.8K followers, 102.8K engagements

"Testicular degeneration will continue until the lipid peroxidation situation improves. Lipid peroxidation driven by polyunsaturated fats destroys the testicles. Shrinkage Lower testosterone Lower fertility The consumption of polyunsaturated fats from seed oils and non-ruminant fat (pork/poultry) is the main driver. Stop Vitamin E coconut oil and dietary lipid peroxidation inhibitors like those found in citrus fruits can help slow the process"
X Link @lowmegatron 2025-09-15T14:55Z 29.8K followers, 189.9K engagements

"Red light can restore the enzyme activity and they've measured rats' cognitive ability and oxygen consumption in their brains just shining red light through their head. It restores their mitochondrial oxidation very quickly. It has a certain momentum before the stress knocks it out again. So about every XX or XX minutes having a little flash of light on your body would probably help." Ray Peat"
X Link @lowmegatron 2025-10-09T19:55Z 29.8K followers, 83.7K engagements

"Things that can lower or block serotonin: Aspirin - lowers plasma serotonin L-theanine - lowers brain serotonin Thiamine - lowers brain serotonin (correcting deficiency) Glycine - lowers brain serotonin Taurine - lowers brain serotonin Thyroid hormone T3 - lowers brain and nonbrain serotonin (correcting deficiency) Ginger - lowers brain and non-brain serotonin serotonin synthesis and blocks serotonin Cyproheptadine - blocks serotonin Negative air ions - likely decrease brain and non-brain serotonin Vitamin E - lowers brain serotonin Magnesium - lowers brain serotonin (correcting deficiency)"
X Link @lowmegatron 2025-10-12T21:00Z 29.8K followers, 128.8K engagements

"My friends with the progesterone babies had all kinds of stories about the precocious things they would do. The most recent story I heard about a couple of them one of them I think shes four years old she had just started a notebook. The grandfather told me that she had written out in her notebook some pages with her eight-year-old brothers name and the grandfathers name and had drawn three lines under her brothers and five lines under her grandfathers name. And he asked what that was for and she said I want each of you to teach new things every day. He asked why he had five lines and her"
X Link @lowmegatron 2025-10-15T18:10Z 29.8K followers, 14.5K engagements

"Fasting kills hair stem cells. It is worth noting that dramatic weight loss by any means is also known to be associated with hair loss known as telogen ef uvium. Fasting is a great way to lower thyroid hormone activity increase stress hormones and boost "fat burning" all of which contribute to hair loss. Upon fasting adrenal glands produce hormones cortisol and epinephrine which then cause lipolysis to release free fatty acids. The release of these free fatty acids near the hair follicles causes apoptosis of HFSC and subsequently blocks hair growth. Ketogenic and high-fat diets are known to"
X Link @lowmegatron 2025-10-14T14:55Z 29.8K followers, 99.2K engagements

"They looked at longevity figures for I think it was in the hundreds of thousands of women in Hungary and they saw a very neat relationship. Lifespan increased in proportion to the number of babies they had had up to eight babies per woman. They had the longest life expectancy showing apparently the same pregnancy effect leaving a residually higher progesterone level in the body reversing the pro-aging effects of estrogen. Ray Peat"
X Link @lowmegatron 2025-10-14T17:35Z 29.8K followers, 5905 engagements

"Some people get hives just from getting cold or from exercising or from not eating soon enough. Just dropping your blood sugar works the same as cutting off the oxygen supply. It keeps that crucial oxidative enzyme from getting the energy from the glucose and the carbon dioxide which should be produced from burning the carbohydrate. And in the absence of sugar oxygen or carbon dioxide that enzyme is going to fail and that causes the cell to produce lactic acid defensively. The lactic acid then triggers chain reactions causes fat to break down (lipolysis increasing free fatty acids) and if you"
X Link @lowmegatron 2025-10-10T18:55Z 29.8K followers, 8133 engagements

"Hypothyroid people are XX times more likely to have SIBO. Hypothyroidism: ➥ Slows gut transit time ➥ Swells the gut lining ➥ Reduces stomach acid SIBO (small intestinal bacterial overgrowth is one of the most common causes of chronic bloating. It causes: ➥ Excess fermentation in the small intestine ➥ Gas accumulation and distension/bloat ➥ Inflammation and water retention ➥ Slowed motility "A very hypothyroid person sometimes has bacteria and yeast living in the stomach." Ray Peat The history of overt hypothyroidism is associated with bacterial overgrowth development. PMID: 17698907"
X Link @lowmegatron 2025-09-26T13:55Z 29.8K followers, 115.6K engagements

""I saw some people with extreme hypothyroidism who would oscillate between extreme depression and extreme mania. When they were going into depression their temperature would be consistently low and once they switched over to the manic phase they would wake up with a pulse rate of maybe XX or XX and a temperature right where Broda Barnes wanted it." Ray Peat"
X Link @lowmegatron 2025-10-14T18:10Z 29.8K followers, 11.8K engagements

"Light is the most effective treatment for Hashimotos TSH Waist Weight Antibodies Inflammation Medication use Thyroid hormone (T3) Structural abnormalities XX% no longer needed thyroid meds But it has to be done correctly. Lets look at the research 🧵"
X Link @lowmegatron 2025-10-09T17:55Z 29.8K followers, 120.7K engagements

"If artificial light is bright enough it is as effective as sunlight at stopping the stress reaction but people seldom use lights that are bright enough. Generally people and animals are healthier when days are longer than XX hours that is after March XX and before September XX. When days are shorter than XX hours artificial lights should be used from sunset until bedtime but the greatest brightness probably doesn't have to be continuous. Studies on isolated organs and tissues suggest that a few seconds of penetrating bright light are enough to break the free radical chain reactions slowing"
X Link @lowmegatron 2025-10-12T14:55Z 29.6K followers, 9067 engagements

"Whats going on with Coke and testicles Higher testosterone Bigger cajones Increased androgen receptor expression On day XX the mass of the mice's testicles was significantly higher in the groups that drank Coca-Cola and XXX percent Pepsi compared to the XX percent Pepsi and control groups. After XX days the control group's testosterone concentration was around XX nanomoles (nmol) per liter whereas the groups which drank pure Coca-Cola and Pepsi had a concentration that was roughly XX nmol/L. a high dose of Pepsi-Cola or Coca-Cola could promote testis growth and development. the concentrations"
X Link @lowmegatron 2025-10-12T16:55Z 29.8K followers, 177.3K engagements

"GM ☕ The risk of depression drops X% per cup of coffee. The risk of depression decreases at XX mg of caffeine/day. The risk gets progressively lower up to XXX mg/day. PMID: 26339067"
X Link @lowmegatron 2025-10-13T13:55Z 29.8K followers, 6342 engagements

"Most unexpected sleep aid"
X Link @lowmegatron 2025-10-09T20:55Z 29.8K followers, 51.9K engagements

"In the 30s it was standard knowledge that arthritis was usually a sign of hypothyroidism. I had a friend who was in his 70s and had an accident and immediately started developing arthritis and was crippled pretty suddenly by arthritis in his hands and feet and knees. And he luckily had a doctor who had been educated in the 1930s who immediately tested his thyroid because stress and injury can lower your thyroid. And my friend was grumpy and said I didnt go to have you fix my thyroid. I wanted you to fix the arthritis. But within two weeks his arthritis cleared up and he lived XX years more"
X Link @lowmegatron 2025-10-01T15:55Z 29.8K followers, 166.1K engagements

"B1 and B2 are essential for estrogen detoxification. . deficiency of either one effectively aborts the estradiol inactivation process. "B2 and B1 are essential in the metabolism of esradiol by liver slices. The inactivation of esradiol is dependent upon the concentration of these vitamins in the liver.""
X Link @lowmegatron 2025-10-09T14:43Z 29.8K followers, 15.8K engagements

"@PetFish__ I have seen people note effects from XXX to 2000 mg"
X Link @lowmegatron 2025-10-13T15:24Z 29.7K followers, XXX engagements

"I can and they are. The fact that you don't understand the cause someone elses condition does not mean that it is psychosomatic. I don't like the way psychobabblers attribute things they don't understand to things that are not real. There is plenty we don't know sure but in this case "we" know quite a lot you don't"
X Link @lowmegatron 2025-10-13T11:33Z 29.7K followers, XX engagements

"T2 works just the same as T3 practically. The characteristic of a thyroid product (NDT) is that it's almost pure protein defatted and we digest it and in the process of digesting the thyroglobulin our enzymes release the T4 and T3 and some T2 hormone. Ray Peat"
X Link @lowmegatron 2025-10-08T20:23Z 29.8K followers, 8378 engagements

"Aspirin may prevent colorectal cancer by improving gut microbiota. Aspirin is associated with decreased risk of colorectal cancer (CRC) potentially by modulating the gut microbiome. Compared to placebo aspirin intake influenced several microbial taxa in a direction consistent with a priori hypothesis based on their association with CRC. This suggests that aspirin may influence CRC development through an effect on the gut microbiome. PMID: 32770859"
X Link @lowmegatron 2025-10-11T15:55Z 29.8K followers, 57.4K engagements

"Thyroid hormone (T3) increases brain energy and reduces depression in some patients. When thyroid treatment for depression is successful ATP (energy molecule) is increased while phosphocreatine (energy backup) is decreased. As energy production increases depression fades. Most of the brain's energy comes from glucose oxidation in normal circumstances and when glucose oxidation is impaired ATP/energy drops. "The antidepressant effect of thyroid hormone (T3) augmentation of SSRIs is correlated with significant changes in the brain bioenergetic metabolism. This seems to be a re-normalization of"
X Link @lowmegatron 2025-10-02T15:55Z 29.8K followers, 135.7K engagements

"Infertility has many possible causes-and certainly among them is thyroid deficiency. Animals thyroidectomized at an early age lack reproductive power. Baby rabbits whose thyroids are removed at the age of three weeks never mate. Cretinized female swine in experiments I have carried out have never come into detectable estrus. Broda Barnes"
X Link @lowmegatron 2025-10-15T16:55Z 29.8K followers, 3259 engagements