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@ByMadeleineA
"eVOLVE-RCC02 paused after "potential immune-mediated adverse events" $RCUS $AZN"
X Link @ByMadeleineA 2025-10-29T09:19Z 8120 followers, 1829 engagements
"It's officially over for cobolimab although that's been on the cards for a while $GSK"
X Link @ByMadeleineA 2025-10-29T09:50Z 8120 followers, 2150 engagements
"$AVBP looks for lung cancer white space with its EGFR inhibitor firmonertinib at #WCLC24. Via @ApexOnco"
X Link @ByMadeleineA 2024-09-09T16:32Z 8112 followers, 4394 engagements
"Carvykti is nearly a blockbuster: $963m in sales in FY 2024 ($334m in Q4 ) $JNJ $LEGN"
X Link @ByMadeleineA 2025-01-22T12:15Z 8119 followers, 10.6K engagements
"And another trial failure sneaked into Q2 earnings this time for $GSK's anti-TIM3 MAb cobolimab"
X Link @ByMadeleineA 2025-07-30T09:09Z 8116 followers, 5185 engagements
"Sounds like more bad news for $IPHA's NK engagers. Here's my previous take on $SNY handing back other NK projects"
X Link @ByMadeleineA 2025-09-17T08:51Z 8115 followers, 2267 engagements
"$AZN gives the PDUFA date for Enhertu + Perjeta in 1st-line HER2+ve as "Q1 2026" but $DSKNY is more specific: XX Jan (use based on Destiny-Breast09)"
X Link @ByMadeleineA 2025-09-24T08:35Z 8112 followers, 2959 engagements
"Compare the wording on OS from $AZN & $DSKNY on Tropion-Breast02 vs $GILD on Ascent-03. Datroway "stat sig & clinically meaningful" on both PFS & OS but only "no OS detriment" for Trodelvy"
X Link @ByMadeleineA 2025-10-06T08:24Z 8116 followers, 9456 engagements
"We were right about Tropion-Breast02 $AZN #ESMO25"
X Link @ByMadeleineA 2025-10-13T08:52Z 8112 followers, 5315 engagements
"Enhertus perioperative Destiny beckons but watch out for ILD. The @ApexOnco take on Destiny-Breast05 & Destiny-Breast11 data at #ESMO25 $AZN $DSKNY"
X Link @ByMadeleineA 2025-10-18T17:46Z 8116 followers, 3089 engagements
"Cross-trial comparison of Datroway vs Trodelvy in first-line TNBC at #ESMO25. $AZN & $DSNKY have the edge over $GILD (OS data immature with Trodelvy)"
X Link @ByMadeleineA 2025-10-19T06:51Z 8115 followers, 5773 engagements
"PFS curves with Trodelvy in Ascent-03 $GILD #ESMO25"
X Link @ByMadeleineA 2025-10-19T07:23Z 8115 followers, XXX engagements
"The #ESMO25 discussant Dr Ana Garrido-Castro weighs in on how to choose between Trodelvy & Datroway"
X Link @ByMadeleineA 2025-10-19T07:59Z 8112 followers, 1214 engagements
"Missed this at the time of the presentation as footnote is so small: X gr3 pneumonitis then death in Tropion-Breast02 was deemed related to disease $AZN $DSNKY #ESMO25"
X Link @ByMadeleineA 2025-10-19T09:44Z 8112 followers, 4135 engagements
"Responses across cancer types and in PDAC with $INCY's KRAS G12D inhibitor at #ESMO25"
X Link @ByMadeleineA 2025-10-19T13:16Z 8115 followers, 2578 engagements
"German Merck's #ESMO25 booth. Well that's one way to wake yourself up on a tired Monday morning"
X Link @ByMadeleineA 2025-10-20T07:15Z 8115 followers, 2411 engagements
"More info on Stellar-303 deaths #ESMO25"
X Link @ByMadeleineA 2025-10-20T07:39Z 8119 followers, 1147 engagements
"Am I reading this right That XX% 2L pancreatic ORR with vopimetostat came in X patients Why hasn't $TNGX provided a waterfall plot"
X Link @ByMadeleineA 2025-10-23T15:21Z 8115 followers, 14.5K engagements
"Another project gone: $INCY's BET inhibitor INCB57643"
X Link @ByMadeleineA 2025-10-28T12:01Z 8120 followers, 3916 engagements
"As for $GSK's IDRx buy the second-line StrateGIST X trial of GSK6042981 has just been unveiled and a first-line trial is to start in 2026"
X Link @ByMadeleineA 2025-10-29T10:02Z 8120 followers, 1046 engagements
"More $GSK discontinuations. As well as cobolimab GSK4381562 (anti-PVRIG) & nelistotug (anti-CD96) are also gone"
X Link @ByMadeleineA 2025-10-29T10:12Z 8120 followers, XXX engagements
"$BMY has removed a SOS1 inhibitor from its pipeline. Must be BMS-986509 or MRTX0902 originally from Mirati"
X Link @ByMadeleineA 2025-10-30T12:09Z 8120 followers, 1322 engagements
"BMS-986506 is possibly a HIF2 inhibitor. No idea about BMS-986523 $BMY"
X Link @ByMadeleineA 2025-10-30T12:11Z 8120 followers, XXX engagements