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@nicknorwitz Avatar @nicknorwitz Nick Norwitz MD PhD

Nick Norwitz MD PhD posts on X about icy, health, derivatives, scale the most. They currently have XXXXXXX followers and XX posts still getting attention that total XXXXX engagements in the last XX hours.

Engagements: XXXXX #

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Mentions: XX #

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Followers: XXXXXXX #

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Social Influence

Social category influence finance X%

Social topic influence icy #130, health 10%, derivatives 5%, scale 5%, science 5%, buckle 5%, reduce 5%, mice 5%, cascade X%

Top accounts mentioned or mentioned by @realdavefeldman @adriansotomota @apodudz @ldlskeptic @akoutnik @janellison @bschermd @mlipivore @jon_8675309 @drericrodgers @dominicdagosti2 @bryanjohnson @natureaging @bryanjohnsons @derekfitness @stevenbartlett @hubermanlab @kimkardashian @jeverettlearned @lipofan

Top Social Posts

Top posts by engagements in the last XX hours

"I just completed a month-long sardine diet. 1/5)The results were. surprising 😳 👉Body fat (7%) 👉Omega-3 levels off the chart (literally XX% higher than the visual scale goes and XXX% above reference range) 👉Energy = Excellent (after some tweaks) 👉Cold Resistant. Maybe an impact of omega-3 on thermogenesis (via omega-3 derivatives e.g. 12-HEPE)"
X Link 2025-11-13T12:15Z 114.2K followers, 937.2K engagements

"4/7) As the authors themselves concluded these associations were too weak to fulfill the conditions required for a surrogate LDL cholesterol to be considered valid. Simply put: this calls into serious question whether LDL can be used as a surrogate for clinical outcomes in statin trials"
X Link 2025-12-06T12:10Z 114.2K followers, XXX engagements

"When The Cholesterol Drop Misses the Mark (Links in 6/7 and 7/7) 1/7) Can we assume that how much LDL drops tells us how much cardiovascular risk is reduced A new meta-analysis in the European Heart Journal says No. In fact it suggests the link between LDL-C reduction and actual cardiovascular outcomes is incredibly weak. So have we built a multi-billion-dollar industry on the assumption that hot chocolate equals real illness Lets unpack that cc @realDaveFeldman @AdrianSotoMota @ApoDudz @DrEricRodgers @LDLSkeptic @AKoutnik @janellison @bschermd"
X Link 2025-12-06T12:10Z 114.2K followers, 21.7K engagements

"Sardines Accidentally Supercharged my Metabolism(link in 8/8) 1/8) Now I want to follow-up on one of the strangest findings from the Sardine Diet Experiment. I became cold-resistant. Taking off my shirt on an icy Boston winter day felt almost like a cool soothing summer breeze. It felt weird. It was unexpected. But it also makes sense. Let's discuss"
X Link 2025-12-11T12:07Z 114.2K followers, 303.1K engagements

"Sardines Sleep & Super-Longevity 👇 Youre going to love this one Professor @DominicDAgosti2 is back to dive into sardine fasting sleep science melatonin myths and the pursuit of super longevity. Ive got nothing else to say except: buckle up. 🔗"
X Link 2025-12-10T12:06Z 114.2K followers, 28.3K engagements

"Meta-analysis of XXX RCTs find #lowcarb diets improve heart health across populations. They're always more nuances but the myth that low-carb is bad for heart health is as ridiculous as. 👇"
X Link 2025-12-11T19:36Z 114.2K followers, 13.7K engagements

"Omega-3 (1/g) $X Million Anti-Aging Protocol Okay this is interesting @bryan_johnson: A paper was published in @NatureAging (PMID: 39900648) investigating the effect of Omega-3 w/ and w/o vitamin D and/or Exercise on X biological aging clocks. One DunedinPACE measures estimate the rate of biological aging defined as the rate of decline in overall system integrity. Pace-of-aging values correspond to the years of biological aging experienced during a single calendar year. A value of X represents the typical pace of aging in a reference population. This appears to be the "rate of aging" clock"
X Link 2025-03-01T14:33Z 114.2K followers, 25.6K engagements

"🚨How Berberine Lowers Cholesterol: Blew My Mind (link at the end) 1/6) I just learned how berberine lowers LDL-C/ApoB and the mechanism blew my mind. Unlike statins it doesnt inhibit cholesterol synthesis or harm mitochondria and doesnt worsen insulin resistance. In fact it improves features of metabolic health while also lowering LDL and ApoB in a totally unexpected way. Lets break it down. ⚠ Warning: This is a heart-health nerd's only zone. Proceed at your own risk especially with 4/6. @ApoDudz @lipo_fan @realDaveFeldman @AdrianSotoMota @LDLSkeptic @AKoutnik @janellison @bschermd"
X Link 2025-11-25T12:03Z 114.1K followers, 59.5K engagements

"4/8) The researchers started with a mouse model. Mice were exposed to cold temperatures (5C) or thermoneutrality (room temperature). After cold exposure researchers measured changes in circulating blood metabolites. Several metabolites increased with cold exposure but one that stood out was 12-HEPE"
X Link 2025-12-11T12:07Z 114.1K followers, 1827 engagements

"5/8) Further experiments showed that cold exposure activated a signaling cascade: Cold exposure activates -adrenergic signaling. This triggers activation of 12-LOX (short-term); and it triggers increased 12-LOX gene expression (longer term) amplifying its effect. 12-LOX turns omega-3 into 12-HEPE. 12-HEPE is secreted and can act on brown fat to increase glucose uptake and thermogenesis (heat production) and increase glucose uptake into muscle"
X Link 2025-12-11T12:07Z 114.1K followers, 1700 engagements

"5/7) These data arent an outlier. Another study published in JAMA Internal Medicine reviewed XX RCTs comparing. Heres what they found and Ill quote directly:"
X Link 2025-12-06T12:10Z 114.2K followers, XXX engagements

"Sardines Made Me Cold Resistant 🐟❄ It Was the WEIRDEST Feeling. There's a biological basis for how this could work: Omega-3 turned into a hormone called 12-HEPE that stimulates thermogenesis 🙋♀ Questions (Planning an interview with a world-leader in Omega-3 metabolism) 🔗 at the end of associated thread"
X Link 2025-12-12T15:14Z 114.2K followers, 7749 engagements